Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2068146558', 'doi': 'https://doi.org/10.1016/s0006-291x(03)00615-6', 'title': 'Mechanisms of cytochrome c release by proapoptotic BCL-2 family members', 'display_name': 'Mechanisms of cytochrome c release by proapoptotic BCL-2 family members', 'publication_year': 2003, 'publication_date': '2003-04-30', 'ids': {'openalex': 'https://openalex.org/W2068146558', 'doi': 'https://doi.org/10.1016/s0006-291x(03)00615-6', 'mag': '2068146558', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12729577'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0006-291x(03)00615-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5051195022', 'display_name': 'Luca Scorrano', 'orcid': 'https://orcid.org/0000-0002-8515-8928'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Luca Scorrano', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.', 'institution_ids': ['https://openalex.org/I1344073410']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109113107', 'display_name': 'Stanley J. Korsmeyer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stanley J. Korsmeyer', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.', 'institution_ids': ['https://openalex.org/I1344073410']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2770, 'currency': 'USD', 'value_usd': 2770, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 8.187, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 705, 'citation_normalized_percentile': {'value': 0.999693, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '304', 'issue': '3', 'first_page': '437', 'last_page': '444'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10294', 'display_name': 'Cell death mechanisms and regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10294', 'display_name': 'Cell death mechanisms and regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12763', 'display_name': 'ATP Synthase and ATPases Research', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 0.9918, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bcl-2-family', 'display_name': 'Bcl-2 Family', 'score': 0.8507794}, {'id': 'https://openalex.org/keywords/mitochondrial-apoptosis-induced-channel', 'display_name': 'Mitochondrial apoptosis-induced channel', 'score': 0.6759403}, {'id': 'https://openalex.org/keywords/apoptosome', 'display_name': 'Apoptosome', 'score': 0.6178313}], 'concepts': [{'id': 'https://openalex.org/C29311851', 'wikidata': 'https://www.wikidata.org/wiki/Q408223', 'display_name': 'Cytochrome c', 'level': 3, 'score': 0.88548416}, {'id': 'https://openalex.org/C149150037', 'wikidata': 'https://www.wikidata.org/wiki/Q554446', 'display_name': 'Bcl-2 family', 'level': 4, 'score': 0.8507794}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.7189616}, {'id': 'https://openalex.org/C28859421', 'wikidata': 'https://www.wikidata.org/wiki/Q39572', 'display_name': 'Mitochondrion', 'level': 2, 'score': 0.70681375}, {'id': 'https://openalex.org/C173358068', 'wikidata': 'https://www.wikidata.org/wiki/Q6881847', 'display_name': 'Mitochondrial apoptosis-induced channel', 'level': 4, 'score': 0.6759403}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.63956654}, {'id': 'https://openalex.org/C2780768313', 'wikidata': 'https://www.wikidata.org/wiki/Q408068', 'display_name': 'Cytochrome', 'level': 3, 'score': 0.62647194}, {'id': 'https://openalex.org/C193349765', 'wikidata': 'https://www.wikidata.org/wiki/Q2061363', 'display_name': 'Apoptosome', 'level': 5, 'score': 0.6178313}, {'id': 'https://openalex.org/C75385678', 'wikidata': 'https://www.wikidata.org/wiki/Q4896390', 'display_name': 'Inner mitochondrial membrane', 'level': 3, 'score': 0.5183281}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.45558697}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37234318}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.27322698}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.22830132}, {'id': 'https://openalex.org/C98424977', 'wikidata': 'https://www.wikidata.org/wiki/Q25805', 'display_name': 'Caspase', 'level': 4, 'score': 0.17775717}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.077993244}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003574', 'descriptor_name': 'Cytochrome c Group', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019253', 'descriptor_name': 'Proto-Oncogene Proteins c-bcl-2', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003574', 'descriptor_name': 'Cytochrome c Group', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007425', 'descriptor_name': 'Intracellular Membranes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019253', 'descriptor_name': 'Proto-Oncogene Proteins c-bcl-2', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D019253', 'descriptor_name': 'Proto-Oncogene Proteins c-bcl-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050998', 'descriptor_name': 'bcl-2 Homologous Antagonist-Killer Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051028', 'descriptor_name': 'bcl-2-Associated X Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0006-291x(03)00615-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12729577', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.66}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 87, 'referenced_works': ['https://openalex.org/W1497532563', 'https://openalex.org/W1507812324', 'https://openalex.org/W1557686543', 'https://openalex.org/W1566777539', 'https://openalex.org/W1593219141', 'https://openalex.org/W1593734817', 'https://openalex.org/W1594300713', 'https://openalex.org/W1644794975', 'https://openalex.org/W1913661233', 'https://openalex.org/W1920479129', 'https://openalex.org/W1963715201', 'https://openalex.org/W1970842110', 'https://openalex.org/W1976720365', 'https://openalex.org/W1982687089', 'https://openalex.org/W1984547206', 'https://openalex.org/W1987785848', 'https://openalex.org/W1987952787', 'https://openalex.org/W1988178204', 'https://openalex.org/W1988353980', 'https://openalex.org/W1993059855', 'https://openalex.org/W1994611236', 'https://openalex.org/W2000352412', 'https://openalex.org/W2000834350', 'https://openalex.org/W2001543531', 'https://openalex.org/W2002350157', 'https://openalex.org/W2002973070', 'https://openalex.org/W2003346050', 'https://openalex.org/W2003507857', 'https://openalex.org/W2005593970', 'https://openalex.org/W2006897943', 'https://openalex.org/W2008348307', 'https://openalex.org/W2009032298', 'https://openalex.org/W2010953153', 'https://openalex.org/W2012173926', 'https://openalex.org/W2012974735', 'https://openalex.org/W2013091489', 'https://openalex.org/W2013319326', 'https://openalex.org/W2013364831', 'https://openalex.org/W2018119239', 'https://openalex.org/W2024996523', 'https://openalex.org/W2025713422', 'https://openalex.org/W2026873116', 'https://openalex.org/W2028023732', 'https://openalex.org/W2032233723', 'https://openalex.org/W2039276913', 'https://openalex.org/W2049873418', 'https://openalex.org/W2052793452', 'https://openalex.org/W2053509579', 'https://openalex.org/W2054820743', 'https://openalex.org/W2057713336', 'https://openalex.org/W2062853648', 'https://openalex.org/W2063362926', 'https://openalex.org/W2063817664', 'https://openalex.org/W2070764343', 'https://openalex.org/W2075477970', 'https://openalex.org/W2081690888', 'https://openalex.org/W2083038107', 'https://openalex.org/W2083906562', 'https://openalex.org/W2086735769', 'https://openalex.org/W2093628776', 'https://openalex.org/W2109564403', 'https://openalex.org/W2113999599', 'https://openalex.org/W2116722945', 'https://openalex.org/W2126376871', 'https://openalex.org/W2131630711', 'https://openalex.org/W2132411546', 'https://openalex.org/W2135167542', 'https://openalex.org/W2136269288', 'https://openalex.org/W2139150415', 'https://openalex.org/W2140967934', 'https://openalex.org/W2146983373', 'https://openalex.org/W2147551208', 'https://openalex.org/W2152247516', 'https://openalex.org/W2154778632', 'https://openalex.org/W2158398965', 'https://openalex.org/W2158498299', 'https://openalex.org/W2158552404', 'https://openalex.org/W2160169717', 'https://openalex.org/W2164799217', 'https://openalex.org/W2166601968', 'https://openalex.org/W2167293805', 'https://openalex.org/W2320279754', 'https://openalex.org/W2408879144', 'https://openalex.org/W2415446381', 'https://openalex.org/W35060329', 'https://openalex.org/W52745064', 'https://openalex.org/W80462140'], 'related_works': ['https://openalex.org/W34494205', 'https://openalex.org/W2321985754', 'https://openalex.org/W2086365629', 'https://openalex.org/W2085715411', 'https://openalex.org/W2068146558', 'https://openalex.org/W2002716364', 'https://openalex.org/W2000605323', 'https://openalex.org/W1644794975', 'https://openalex.org/W1586631084', 'https://openalex.org/W1497764537'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2068146558', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 19}, {'year': 2021, 'cited_by_count': 26}, {'year': 2020, 'cited_by_count': 19}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 24}, {'year': 2017, 'cited_by_count': 21}, {'year': 2016, 'cited_by_count': 29}, {'year': 2015, 'cited_by_count': 41}, {'year': 2014, 'cited_by_count': 25}, {'year': 2013, 'cited_by_count': 30}, {'year': 2012, 'cited_by_count': 24}], 'updated_date': '2025-01-05T09:29:47.811311', 'created_date': '2016-06-24'}