Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2068055758', 'doi': 'https://doi.org/10.1006/jmbi.1998.1654', 'title': 'The muscle thin filament as a classical cooperative/allosteric regulatory system', 'display_name': 'The muscle thin filament as a classical cooperative/allosteric regulatory system', 'publication_year': 1998, 'publication_date': '1998-04-01', 'ids': {'openalex': 'https://openalex.org/W2068055758', 'doi': 'https://doi.org/10.1006/jmbi.1998.1654', 'mag': '2068055758', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9571024'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1006/jmbi.1998.1654', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S46058472', 'display_name': 'Journal of Molecular Biology', 'issn_l': '0022-2836', 'issn': ['0022-2836', '1089-8638'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5064474716', 'display_name': 'Sherwin S. Lehrer', 'orcid': 'https://orcid.org/0000-0002-0284-4472'}, 'institutions': [{'id': 'https://openalex.org/I1309400984', 'display_name': 'Boston Biomedical Research Institute', 'ror': 'https://ror.org/04rqpth59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1309400984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sherwin S Lehrer', 'raw_affiliation_strings': ['Muscle Research Group Boston Biomedical Research Institute, Boston, MA 01224, USA'], 'affiliations': [{'raw_affiliation_string': 'Muscle Research Group Boston Biomedical Research Institute, Boston, MA 01224, USA', 'institution_ids': ['https://openalex.org/I1309400984']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5039484661', 'display_name': 'Michael A. Geeves', 'orcid': 'https://orcid.org/0000-0002-9364-8898'}, 'institutions': [{'id': 'https://openalex.org/I4210130622', 'display_name': 'Max Planck Institute of Molecular Physiology', 'ror': 'https://ror.org/03vpj4s62', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210130622']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Michael A Geeves', 'raw_affiliation_strings': ['Max Planck Institut f. Molekulare Physiologie D-44139, Dortmund Germany'], 'affiliations': [{'raw_affiliation_string': 'Max Planck Institut f. Molekulare Physiologie D-44139, Dortmund Germany', 'institution_ids': ['https://openalex.org/I4210130622']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4250, 'currency': 'USD', 'value_usd': 4250, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 9.325, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 203, 'citation_normalized_percentile': {'value': 0.999899, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '277', 'issue': '5', 'first_page': '1081', 'last_page': '1089'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10882', 'display_name': 'Cardiomyopathy and Myosin Studies', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10882', 'display_name': 'Cardiomyopathy and Myosin Studies', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12094', 'display_name': 'Hemoglobin structure and function', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10949', 'display_name': 'Genetic Neurodegenerative Diseases', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tropomyosin', 'display_name': 'Tropomyosin', 'score': 0.83149195}], 'concepts': [{'id': 'https://openalex.org/C166342909', 'wikidata': 'https://www.wikidata.org/wiki/Q845326', 'display_name': 'Allosteric regulation', 'level': 3, 'score': 0.87335604}, {'id': 'https://openalex.org/C205875245', 'wikidata': 'https://www.wikidata.org/wiki/Q418454', 'display_name': 'Tropomyosin', 'level': 3, 'score': 0.83149195}, {'id': 'https://openalex.org/C6997183', 'wikidata': 'https://www.wikidata.org/wiki/Q271727', 'display_name': 'Myosin', 'level': 2, 'score': 0.74748814}, {'id': 'https://openalex.org/C125705527', 'wikidata': 'https://www.wikidata.org/wiki/Q185269', 'display_name': 'Actin', 'level': 2, 'score': 0.7245579}, {'id': 'https://openalex.org/C36036425', 'wikidata': 'https://www.wikidata.org/wiki/Q7846262', 'display_name': 'Troponin', 'level': 3, 'score': 0.63706696}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5681594}, {'id': 'https://openalex.org/C104292427', 'wikidata': 'https://www.wikidata.org/wiki/Q899781', 'display_name': 'Protein subunit', 'level': 3, 'score': 0.5590867}, {'id': 'https://openalex.org/C15954220', 'wikidata': 'https://www.wikidata.org/wiki/Q24780076', 'display_name': 'Myosin head', 'level': 4, 'score': 0.52565753}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.47514176}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.43874574}, {'id': 'https://openalex.org/C2776050358', 'wikidata': 'https://www.wikidata.org/wiki/Q127006', 'display_name': 'Muscle contraction', 'level': 2, 'score': 0.42850265}, {'id': 'https://openalex.org/C8035138', 'wikidata': 'https://www.wikidata.org/wiki/Q6017854', 'display_name': 'Myosin light-chain kinase', 'level': 3, 'score': 0.41113883}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3219869}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.16279736}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.12375188}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C500558357', 'wikidata': 'https://www.wikidata.org/wiki/Q12152', 'display_name': 'Myocardial infarction', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009124', 'descriptor_name': 'Muscle Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000205', 'descriptor_name': 'Actomyosin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000205', 'descriptor_name': 'Actomyosin', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D000251', 'descriptor_name': 'Adenosine Triphosphatases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000251', 'descriptor_name': 'Adenosine Triphosphatases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000494', 'descriptor_name': 'Allosteric Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000494', 'descriptor_name': 'Allosteric Regulation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001221', 'descriptor_name': 'Aspartate Carbamoyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001221', 'descriptor_name': 'Aspartate Carbamoyltransferase', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006454', 'descriptor_name': 'Hemoglobins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006454', 'descriptor_name': 'Hemoglobins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009124', 'descriptor_name': 'Muscle Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014335', 'descriptor_name': 'Tropomyosin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014335', 'descriptor_name': 'Tropomyosin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014336', 'descriptor_name': 'Troponin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014336', 'descriptor_name': 'Troponin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1006/jmbi.1998.1654', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S46058472', 'display_name': 'Journal of Molecular Biology', 'issn_l': '0022-2836', 'issn': ['0022-2836', '1089-8638'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9571024', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W100430351', 'https://openalex.org/W14251027', 'https://openalex.org/W1490442168', 'https://openalex.org/W1575133104', 'https://openalex.org/W1589610797', 'https://openalex.org/W1595817081', 'https://openalex.org/W1603479071', 'https://openalex.org/W1620274191', 'https://openalex.org/W1692710312', 'https://openalex.org/W1747748421', 'https://openalex.org/W1959167627', 'https://openalex.org/W1974381583', 'https://openalex.org/W1975475509', 'https://openalex.org/W1988036478', 'https://openalex.org/W1992924616', 'https://openalex.org/W1998093640', 'https://openalex.org/W2003300699', 'https://openalex.org/W2005809336', 'https://openalex.org/W2008186189', 'https://openalex.org/W2010536798', 'https://openalex.org/W2017331175', 'https://openalex.org/W2018225090', 'https://openalex.org/W2019642924', 'https://openalex.org/W2025071422', 'https://openalex.org/W2026145805', 'https://openalex.org/W2028569629', 'https://openalex.org/W2036414089', 'https://openalex.org/W2036925114', 'https://openalex.org/W2039817964', 'https://openalex.org/W2045156603', 'https://openalex.org/W2046919025', 'https://openalex.org/W2048114117', 'https://openalex.org/W2049350695', 'https://openalex.org/W2049607475', 'https://openalex.org/W2059086329', 'https://openalex.org/W2062792913', 'https://openalex.org/W2070037836', 'https://openalex.org/W2072366123', 'https://openalex.org/W2080309405', 'https://openalex.org/W2086375139', 'https://openalex.org/W2088432680', 'https://openalex.org/W2105944799', 'https://openalex.org/W2113092027', 'https://openalex.org/W2170249054', 'https://openalex.org/W2175328062', 'https://openalex.org/W2180504913', 'https://openalex.org/W2210986612', 'https://openalex.org/W2312518076', 'https://openalex.org/W2334869316', 'https://openalex.org/W2435566390', 'https://openalex.org/W4230158786'], 'related_works': ['https://openalex.org/W3224045', 'https://openalex.org/W2176481193', 'https://openalex.org/W2120759692', 'https://openalex.org/W2068551528', 'https://openalex.org/W2048114117', 'https://openalex.org/W2025536895', 'https://openalex.org/W2010503455', 'https://openalex.org/W2009749095', 'https://openalex.org/W1965571199', 'https://openalex.org/W1566819067'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2068055758', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-15T23:41:58.587903', 'created_date': '2016-06-24'}