Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2066118258', 'doi': 'https://doi.org/10.1083/jcb.138.3.657', 'title': 'Suppression of KIF2 in PC12 Cells Alters the Distribution of a Growth Cone Nonsynaptic Membrane Receptor and Inhibits Neurite Extension', 'display_name': 'Suppression of KIF2 in PC12 Cells Alters the Distribution of a Growth Cone Nonsynaptic Membrane Receptor and Inhibits Neurite Extension', 'publication_year': 1997, 'publication_date': '1997-08-11', 'ids': {'openalex': 'https://openalex.org/W2066118258', 'doi': 'https://doi.org/10.1083/jcb.138.3.657', 'mag': '2066118258', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9245793', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2141628'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.138.3.657', 'pdf_url': 'https://rupress.org/jcb/article-pdf/138/3/657/1272077/32807.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://rupress.org/jcb/article-pdf/138/3/657/1272077/32807.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070073548', 'display_name': 'Gerardo Morfini', 'orcid': 'https://orcid.org/0000-0001-6059-5518'}, 'institutions': [{'id': 'https://openalex.org/I4210112829', 'display_name': 'Research Centre in Biological Chemistry of Córdoba', 'ror': 'https://ror.org/023dgw813', 'country_code': 'AR', 'type': 'facility', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829', 'https://openalex.org/I4210123736', 'https://openalex.org/I4210130626', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Gerardo Morfini', 'raw_affiliation_strings': ["*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115"], 'affiliations': [{'raw_affiliation_string': "*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115", 'institution_ids': ['https://openalex.org/I4210112829', 'https://openalex.org/I151201029', 'https://openalex.org/I166401450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078649753', 'display_name': 'Santiago Quiroga', 'orcid': 'https://orcid.org/0000-0001-9087-7591'}, 'institutions': [{'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I4210112829', 'display_name': 'Research Centre in Biological Chemistry of Córdoba', 'ror': 'https://ror.org/023dgw813', 'country_code': 'AR', 'type': 'facility', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829', 'https://openalex.org/I4210123736', 'https://openalex.org/I4210130626', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Santiago Quiroga', 'raw_affiliation_strings': ["*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115"], 'affiliations': [{'raw_affiliation_string': "*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115", 'institution_ids': ['https://openalex.org/I151201029', 'https://openalex.org/I4210112829', 'https://openalex.org/I166401450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039071726', 'display_name': 'Alberto L. Rosa', 'orcid': 'https://orcid.org/0000-0001-8701-4525'}, 'institutions': [{'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}, {'id': 'https://openalex.org/I4210112829', 'display_name': 'Research Centre in Biological Chemistry of Córdoba', 'ror': 'https://ror.org/023dgw813', 'country_code': 'AR', 'type': 'facility', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829', 'https://openalex.org/I4210123736', 'https://openalex.org/I4210130626', 'https://openalex.org/I4387155568']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Alberto Rosa', 'raw_affiliation_strings': ["*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115"], 'affiliations': [{'raw_affiliation_string': "*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115", 'institution_ids': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016853030', 'display_name': 'Kenneth S. Kosik', 'orcid': 'https://orcid.org/0000-0003-3224-5179'}, 'institutions': [{'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}, {'id': 'https://openalex.org/I4210112829', 'display_name': 'Research Centre in Biological Chemistry of Córdoba', 'ror': 'https://ror.org/023dgw813', 'country_code': 'AR', 'type': 'facility', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829', 'https://openalex.org/I4210123736', 'https://openalex.org/I4210130626', 'https://openalex.org/I4387155568']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Kenneth Kosik', 'raw_affiliation_strings': ["*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115"], 'affiliations': [{'raw_affiliation_string': "*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115", 'institution_ids': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5012979018', 'display_name': 'Alfredo Cáceres', 'orcid': 'https://orcid.org/0000-0002-4163-9068'}, 'institutions': [{'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}, {'id': 'https://openalex.org/I4210112829', 'display_name': 'Research Centre in Biological Chemistry of Córdoba', 'ror': 'https://ror.org/023dgw813', 'country_code': 'AR', 'type': 'facility', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829', 'https://openalex.org/I4210123736', 'https://openalex.org/I4210130626', 'https://openalex.org/I4387155568']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Alfredo Cáceres', 'raw_affiliation_strings': ["*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115"], 'affiliations': [{'raw_affiliation_string': "*Instituto Investigación Médica Mercedes y Martín Ferreyra, 5000 Córdoba, Argentina; ‡Departamento Química Biológica, Facultad Ciencias Químicas (CIQUIBIC) Universidad Nacional de Córdoba/CONICET, 5000 Córdoba, Argentina; and §Department of Neurology (Neuroscience), Harvard Medical School and Center for Neurological Diseases, Department of Medicine (Division of Neurology), Brigham and Women's Hospital, Boston, Massachusetts 02115", 'institution_ids': ['https://openalex.org/I151201029', 'https://openalex.org/I166401450', 'https://openalex.org/I4210112829']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.045, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 78, 'citation_normalized_percentile': {'value': 0.839128, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '138', 'issue': '3', 'first_page': '657', 'last_page': '669'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10617', 'display_name': 'Mechanisms of Intracellular Membrane Trafficking', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Regulation of Chromatin Structure and Function', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/growth-cone', 'display_name': 'Growth cone', 'score': 0.84347486}, {'id': 'https://openalex.org/keywords/neurite', 'display_name': 'Neurite', 'score': 0.8397473}, {'id': 'https://openalex.org/keywords/synapsin-i', 'display_name': 'Synapsin I', 'score': 0.57956725}, {'id': 'https://openalex.org/keywords/gap-43-protein', 'display_name': 'Gap-43 protein', 'score': 0.5725281}, {'id': 'https://openalex.org/keywords/synaptophysin', 'display_name': 'Synaptophysin', 'score': 0.55451757}, {'id': 'https://openalex.org/keywords/cell-division', 'display_name': 'Cell Division', 'score': 0.476053}, {'id': 'https://openalex.org/keywords/synaptogenesis', 'display_name': 'Synaptogenesis', 'score': 0.44707292}], 'concepts': [{'id': 'https://openalex.org/C135903288', 'wikidata': 'https://www.wikidata.org/wiki/Q559423', 'display_name': 'Growth cone', 'level': 3, 'score': 0.84347486}, {'id': 'https://openalex.org/C113246987', 'wikidata': 'https://www.wikidata.org/wiki/Q1534415', 'display_name': 'Neurite', 'level': 3, 'score': 0.8397473}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.81050897}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6822637}, {'id': 'https://openalex.org/C148785051', 'wikidata': 'https://www.wikidata.org/wiki/Q671136', 'display_name': 'Synaptic vesicle', 'level': 4, 'score': 0.62743616}, {'id': 'https://openalex.org/C50493954', 'wikidata': 'https://www.wikidata.org/wiki/Q18031806', 'display_name': 'Synapsin I', 'level': 5, 'score': 0.57956725}, {'id': 'https://openalex.org/C90770895', 'wikidata': 'https://www.wikidata.org/wiki/Q14906268', 'display_name': 'Gap-43 protein', 'level': 3, 'score': 0.5725281}, {'id': 'https://openalex.org/C2777209535', 'wikidata': 'https://www.wikidata.org/wiki/Q14864388', 'display_name': 'Synaptophysin', 'level': 3, 'score': 0.55451757}, {'id': 'https://openalex.org/C65232495', 'wikidata': 'https://www.wikidata.org/wiki/Q1813773', 'display_name': 'Synaptogenesis', 'level': 2, 'score': 0.44707292}, {'id': 'https://openalex.org/C130316041', 'wikidata': 'https://www.wikidata.org/wiki/Q189206', 'display_name': 'Vesicle', 'level': 3, 'score': 0.3464163}, {'id': 'https://openalex.org/C2779530196', 'wikidata': 'https://www.wikidata.org/wiki/Q178999', 'display_name': 'Axon', 'level': 2, 'score': 0.2511317}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.21969435}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.09979409}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.099199295}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016547', 'descriptor_name': 'Kinesins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D016501', 'descriptor_name': 'Neurites', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015388', 'descriptor_name': 'Organelles', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016564', 'descriptor_name': 'Amyloid beta-Protein Precursor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D016564', 'descriptor_name': 'Amyloid beta-Protein Precursor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019922', 'descriptor_name': 'GAP-43 Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016547', 'descriptor_name': 'Kinesins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016547', 'descriptor_name': 'Kinesins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D016547', 'descriptor_name': 'Kinesins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016547', 'descriptor_name': 'Kinesins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D008562', 'descriptor_name': 'Membrane Glycoproteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D008562', 'descriptor_name': 'Membrane Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009414', 'descriptor_name': 'Nerve Growth Factors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D009414', 'descriptor_name': 'Nerve Growth Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016501', 'descriptor_name': 'Neurites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D016376', 'descriptor_name': 'Oligonucleotides, Antisense', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016376', 'descriptor_name': 'Oligonucleotides, Antisense', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015388', 'descriptor_name': 'Organelles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015388', 'descriptor_name': 'Organelles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D016716', 'descriptor_name': 'PC12 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017526', 'descriptor_name': 'Receptor, IGF Type 1', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D017526', 'descriptor_name': 'Receptor, IGF Type 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016704', 'descriptor_name': 'Synapsins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D016704', 'descriptor_name': 'Synapsins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013572', 'descriptor_name': 'Synaptic Vesicles', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013572', 'descriptor_name': 'Synaptic Vesicles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013572', 'descriptor_name': 'Synaptic Vesicles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016708', 'descriptor_name': 'Synaptophysin', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D016708', 'descriptor_name': 'Synaptophysin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013873', 'descriptor_name': 'Thionucleotides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013873', 'descriptor_name': 'Thionucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.138.3.657', 'pdf_url': 'https://rupress.org/jcb/article-pdf/138/3/657/1272077/32807.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2141628', 'pdf_url': 'https://europepmc.org/articles/pmc2141628?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141628', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9245793', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.138.3.657', 'pdf_url': 'https://rupress.org/jcb/article-pdf/138/3/657/1272077/32807.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 55, 'referenced_works': ['https://openalex.org/W1514231771', 'https://openalex.org/W1520783088', 'https://openalex.org/W1558257544', 'https://openalex.org/W1931843124', 'https://openalex.org/W1967533184', 'https://openalex.org/W1970587959', 'https://openalex.org/W1974337221', 'https://openalex.org/W1974548484', 'https://openalex.org/W1980617751', 'https://openalex.org/W1985480042', 'https://openalex.org/W1993672117', 'https://openalex.org/W1993762028', 'https://openalex.org/W1995545777', 'https://openalex.org/W1998225973', 'https://openalex.org/W2000303735', 'https://openalex.org/W2003084435', 'https://openalex.org/W2008288388', 'https://openalex.org/W2012855723', 'https://openalex.org/W2013042948', 'https://openalex.org/W2015289511', 'https://openalex.org/W2021008086', 'https://openalex.org/W2021271933', 'https://openalex.org/W2029120000', 'https://openalex.org/W2031316544', 'https://openalex.org/W2032342779', 'https://openalex.org/W2036464759', 'https://openalex.org/W2039901479', 'https://openalex.org/W2042931626', 'https://openalex.org/W2043343021', 'https://openalex.org/W2043706080', 'https://openalex.org/W2051647145', 'https://openalex.org/W2055144059', 'https://openalex.org/W2058040654', 'https://openalex.org/W2073174918', 'https://openalex.org/W2074867892', 'https://openalex.org/W2075095119', 'https://openalex.org/W2078023075', 'https://openalex.org/W2092682565', 'https://openalex.org/W2095476922', 'https://openalex.org/W2100624617', 'https://openalex.org/W2123513862', 'https://openalex.org/W2126955433', 'https://openalex.org/W2131832714', 'https://openalex.org/W2133300036', 'https://openalex.org/W2136354065', 'https://openalex.org/W2136479304', 'https://openalex.org/W2149312421', 'https://openalex.org/W2150287123', 'https://openalex.org/W2153647147', 'https://openalex.org/W2164477294', 'https://openalex.org/W2169832500', 'https://openalex.org/W2170463530', 'https://openalex.org/W2182661714', 'https://openalex.org/W2189214793', 'https://openalex.org/W993271046'], 'related_works': ['https://openalex.org/W2615052221', 'https://openalex.org/W2419191705', 'https://openalex.org/W2167692103', 'https://openalex.org/W2075524910', 'https://openalex.org/W2071037804', 'https://openalex.org/W2026347543', 'https://openalex.org/W2008767130', 'https://openalex.org/W1991471030', 'https://openalex.org/W1986512833', 'https://openalex.org/W1529673013'], 'abstract_inverted_index': {'In': [0], 'the': [1, 8, 29, 32, 101, 113, 117, 152, 166, 184, 198, 263], 'present': [2, 5], 'study,': [3], 'we': [4, 71], 'evidence': [6], 'about': [7], 'cellular': [9], 'functions': [10], 'of': [11, 31, 58, 77, 86, 112, 116, 145, 154, 168, 181, 200, 215, 230, 266, 269, 276], 'KIF2,': [12], 'a': [13, 18, 75, 109, 178, 227, 256, 267, 279, 286], 'kinesin-like': [14], 'superfamily': [15], 'member': [16], 'having': [17], 'unique': [19], 'structure': [20], 'in': [21, 124, 136, 142, 177, 188, 197, 210, 253, 290], 'that': [22, 80, 258, 272], 'its': [23, 189, 277], 'motor': [24], 'domain': [25], 'is': [26, 108, 121], 'localized': [27], 'at': [28, 220], 'center': [30], 'molecule': [33], '(Noda': [34], 'Y.,': [35], 'Y.': [36], 'Sato-Yoshitake,': [37], 'S.': [38], 'Kondo,': [39], 'M.': [40], 'Nangaku,': [41], 'and': [42, 66, 130, 139, 165, 170, 187], 'N.': [43], 'Hirokawa.': [44], '1995.': [45], 'J.': [46], 'Cell': [47], 'Biol.': [48], '129:157–167.).': [49], 'Using': [50], 'subcellular': [51], 'fractionation': [52], 'techniques,': [53], 'isopicnic': [54], 'sucrose': [55], 'density': [56], 'centrifugation': [57], 'microsomal': [59], 'fractions': [60], 'from': [61, 192, 240], 'developing': [62, 146], 'rat': [63], 'cerebral': [64], 'cortex,': [65], 'immunoisolation': [67], 'with': [68, 82, 262], 'KIF2': [69, 131, 155, 174, 223, 252], 'antibodies,': [70], 'have': [72, 149], 'now': [73], 'identified': [74], 'type': [76, 85, 268], 'nonsynaptic': [78, 171, 270], 'vesicle': [79, 90, 172, 271], 'associates': [81], 'KIF2.': [83], 'This': [84], 'organelle': [87], 'lacks': [88], 'synaptic': [89, 169], 'markers': [91], '(synapsin,': [92], 'synaptophysin),': [93], 'amyloid': [94, 205], 'precursor': [95], 'protein,': [96], 'GAP-43,': [97, 203], 'or': [98, 204], 'N-cadherin.': [99], 'On': [100], 'other': [102], 'hand,': [103], 'it': [104], 'contains': [105, 273], 'βgc,': [106], 'which': [107, 120], 'novel': [110], 'variant': [111], 'β': [114], 'subunit': [115], 'IGF-1': [118], 'receptor,': [119], 'highly': [122, 140, 218], 'enriched': [123, 219], 'growth': [125, 143, 193, 241, 280, 287], 'cone': [126, 281], 'membranes.': [127], 'Both': [128], 'βgc': [129, 182, 237], 'are': [132, 208], 'upregulated': [133], 'by': [134, 157], 'NGF': [135], 'PC12': [137], 'cells': [138], 'concentrated': [141], 'cones': [144], 'neurons.': [147, 212], 'We': [148], 'also': [150, 225], 'analyzed': [151], 'consequences': [153], 'suppression': [156, 175, 224], 'antisense': [158], 'oligonucleotide': [159], 'treatment': [160], 'on': [161], 'nerve': [162, 221, 291], 'cell': [163, 185, 292], 'morphogenesis': [164], 'distribution': [167, 199], 'markers.': [173], 'results': [176, 246], 'dramatic': [179, 228], 'accumulation': [180], 'within': [183], 'body': [186], 'complete': [190], 'disappearance': [191], 'cones;': [194], 'no': [195], 'alterations': [196], 'synapsin,': [201], 'synaptophysin,': [202], 'percursor': [206], 'protein': [207], 'detected': [209], 'KIF2-suppressed': [211], 'Instead,': [213], 'all': [214], 'them': [216], 'remained': [217], 'terminals.': [222], 'produces': [226], 'inhibition': [229], 'neurite': [231, 254], 'outgrowth;': [232], 'this': [233], 'phenomenon': [234, 257], 'occurs': [235], 'after': [236], 'has': [238], 'disappeared': [239], 'cones.': [242], 'Taken': [243], 'collectively,': [244], 'our': [245], 'suggest': [247], 'an': [248], 'important': [249], 'role': [250], 'for': [251, 284], 'extension,': [255], 'may': [259], 'be': [260], 'related': [261], 'anterograde': [264], 'transport': [265], 'as': [274], 'one': [275], 'components': [278], 'membrane': [282], 'receptor': [283], 'IGF-1,': [285], 'factor': [288], 'implicated': [289], 'development.': [293]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2066118258', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-13T14:20:07.919890', 'created_date': '2016-06-24'}