Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2065847009', 'doi': 'https://doi.org/10.1053/gast.2001.24053', 'title': 'The cardiac K+ channel KCNQ1 is essential for gastric acid secretion', 'display_name': 'The cardiac K+ channel KCNQ1 is essential for gastric acid secretion', 'publication_year': 2001, 'publication_date': '2001-05-01', 'ids': {'openalex': 'https://openalex.org/W2065847009', 'doi': 'https://doi.org/10.1053/gast.2001.24053', 'mag': '2065847009', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11313306'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1053/gast.2001.24053', 'pdf_url': 'http://www.gastrojournal.org/article/S0016508501333565/pdf', 'source': {'id': 'https://openalex.org/S143352558', 'display_name': 'Gastroenterology', 'issn_l': '0016-5085', 'issn': ['0016-5085', '1528-0012'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.gastrojournal.org/article/S0016508501333565/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004648123', 'display_name': 'Florian Grahammer', 'orcid': 'https://orcid.org/0000-0002-7851-754X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Florian Grahammer', 'raw_affiliation_strings': ['Physiology'], 'affiliations': [{'raw_affiliation_string': 'Physiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064913810', 'display_name': 'Oliver H. Wittekindt', 'orcid': 'https://orcid.org/0000-0002-1890-6471'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Oliver H. Wittekindt', 'raw_affiliation_strings': ['Physiology'], 'affiliations': [{'raw_affiliation_string': 'Physiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063313893', 'display_name': 'Roland Nitschke', 'orcid': 'https://orcid.org/0000-0002-9397-8475'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Roland Nitschke', 'raw_affiliation_strings': ['Physiology'], 'affiliations': [{'raw_affiliation_string': 'Physiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060556419', 'display_name': 'Andreas W. Herling', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Andreas W. Herling', 'raw_affiliation_strings': ['Aventis Pharma GmbH Frankfurt am Main (Germany)'], 'affiliations': [{'raw_affiliation_string': 'Aventis Pharma GmbH Frankfurt am Main (Germany)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114044863', 'display_name': 'Hans J. Lang', 'orcid': None}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Hans J. Lang', 'raw_affiliation_strings': ['Aventis Pharma GmbH Frankfurt am Main (Germany)'], 'affiliations': [{'raw_affiliation_string': 'Aventis Pharma GmbH Frankfurt am Main (Germany)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036442263', 'display_name': 'Markus Bleich', 'orcid': 'https://orcid.org/0000-0002-1745-2295'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Markus Bleich', 'raw_affiliation_strings': ['Aventis Pharma GmbH Frankfurt am Main (Germany)'], 'affiliations': [{'raw_affiliation_string': 'Aventis Pharma GmbH Frankfurt am Main (Germany)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027936838', 'display_name': 'Annette Schmitt‐Graeff', 'orcid': 'https://orcid.org/0000-0001-5082-7979'}, 'institutions': [{'id': 'https://openalex.org/I161046081', 'display_name': 'University of Freiburg', 'ror': 'https://ror.org/0245cg223', 'country_code': 'DE', 'type': 'funder', 'lineage': ['https://openalex.org/I161046081']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Annette Schmitt–Gräff', 'raw_affiliation_strings': ['Pathology, Albert-Ludwigs-University, Freiburg, Germany;'], 'affiliations': [{'raw_affiliation_string': 'Pathology, Albert-Ludwigs-University, Freiburg, Germany;', 'institution_ids': ['https://openalex.org/I161046081']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013230246', 'display_name': 'Jacques Barhanin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210160500', 'display_name': 'Institut de Pharmacologie Moléculaire et Cellulaire', 'ror': 'https://ror.org/05k4ema52', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I201841394', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210160500']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jacques Barhanin', 'raw_affiliation_strings': ['IPMC, CNRS, Valbonne Sophia Antipolis, France'], 'affiliations': [{'raw_affiliation_string': 'IPMC, CNRS, Valbonne Sophia Antipolis, France', 'institution_ids': ['https://openalex.org/I4210160500', 'https://openalex.org/I1294671590']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006230926', 'display_name': 'Richard Warth', 'orcid': 'https://orcid.org/0000-0001-6084-0659'}, 'institutions': [{'id': 'https://openalex.org/I4210160500', 'display_name': 'Institut de Pharmacologie Moléculaire et Cellulaire', 'ror': 'https://ror.org/05k4ema52', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I201841394', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210160500']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Richard Warth', 'raw_affiliation_strings': ['IPMC, CNRS, Valbonne Sophia Antipolis, France'], 'affiliations': [{'raw_affiliation_string': 'IPMC, CNRS, Valbonne Sophia Antipolis, France', 'institution_ids': ['https://openalex.org/I4210160500', 'https://openalex.org/I1294671590']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3800, 'currency': 'USD', 'value_usd': 3800, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.563, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 176, 'citation_normalized_percentile': {'value': 0.974107, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '120', 'issue': '6', 'first_page': '1363', 'last_page': '1371'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10724', 'display_name': 'Ion Transport and Channel Regulation', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/parietal-cell', 'display_name': 'Parietal cell', 'score': 0.6996309}, {'id': 'https://openalex.org/keywords/gastric-chief-cell', 'display_name': 'Gastric chief cell', 'score': 0.51165277}], 'concepts': [{'id': 'https://openalex.org/C2777504413', 'wikidata': 'https://www.wikidata.org/wiki/Q846270', 'display_name': 'Gastric acid', 'level': 3, 'score': 0.77821445}, {'id': 'https://openalex.org/C49039625', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretion', 'level': 2, 'score': 0.70481396}, {'id': 'https://openalex.org/C2779743957', 'wikidata': 'https://www.wikidata.org/wiki/Q1640093', 'display_name': 'Parietal cell', 'level': 4, 'score': 0.6996309}, {'id': 'https://openalex.org/C83743174', 'wikidata': 'https://www.wikidata.org/wiki/Q423778', 'display_name': 'Potassium channel', 'level': 2, 'score': 0.5299134}, {'id': 'https://openalex.org/C66595182', 'wikidata': 'https://www.wikidata.org/wiki/Q2595765', 'display_name': 'Gastric chief cell', 'level': 4, 'score': 0.51165277}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5102391}, {'id': 'https://openalex.org/C2779422922', 'wikidata': 'https://www.wikidata.org/wiki/Q1029907', 'display_name': 'Stomach', 'level': 2, 'score': 0.4673277}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4453552}, {'id': 'https://openalex.org/C147944092', 'wikidata': 'https://www.wikidata.org/wiki/Q176366', 'display_name': 'Patch clamp', 'level': 3, 'score': 0.42881843}, {'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.42699277}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.38822702}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3333419}, {'id': 'https://openalex.org/C185263204', 'wikidata': 'https://www.wikidata.org/wiki/Q1154774', 'display_name': 'Electrophysiology', 'level': 2, 'score': 0.3253696}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25542998}, {'id': 'https://openalex.org/C2781443798', 'wikidata': 'https://www.wikidata.org/wiki/Q383249', 'display_name': 'Gastric mucosa', 'level': 3, 'score': 0.24133256}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.15373805}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.111389905}], 'mesh': [{'descriptor_ui': 'D005744', 'descriptor_name': 'Gastric Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015221', 'descriptor_name': 'Potassium Channels', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D024642', 'descriptor_name': 'Potassium Channels, Voltage-Gated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016466', 'descriptor_name': 'CHO Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006224', 'descriptor_name': 'Cricetinae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004285', 'descriptor_name': 'Dogs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005744', 'descriptor_name': 'Gastric Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005745', 'descriptor_name': 'Gastric Acidity Determination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006632', 'descriptor_name': 'Histamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006632', 'descriptor_name': 'Histamine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051656', 'descriptor_name': 'KCNQ Potassium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051657', 'descriptor_name': 'KCNQ1 Potassium Channel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D026902', 'descriptor_name': 'Potassium Channel Blockers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015221', 'descriptor_name': 'Potassium Channels', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D015221', 'descriptor_name': 'Potassium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013045', 'descriptor_name': 'Species Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1053/gast.2001.24053', 'pdf_url': 'http://www.gastrojournal.org/article/S0016508501333565/pdf', 'source': {'id': 'https://openalex.org/S143352558', 'display_name': 'Gastroenterology', 'issn_l': '0016-5085', 'issn': ['0016-5085', '1528-0012'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11313306', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1053/gast.2001.24053', 'pdf_url': 'http://www.gastrojournal.org/article/S0016508501333565/pdf', 'source': {'id': 'https://openalex.org/S143352558', 'display_name': 'Gastroenterology', 'issn_l': '0016-5085', 'issn': ['0016-5085', '1528-0012'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1520699352', 'https://openalex.org/W1566584097', 'https://openalex.org/W1578508637', 'https://openalex.org/W1602958737', 'https://openalex.org/W1668163968', 'https://openalex.org/W190493681', 'https://openalex.org/W1967880298', 'https://openalex.org/W1970005475', 'https://openalex.org/W1971935780', 'https://openalex.org/W1979005514', 'https://openalex.org/W1979320338', 'https://openalex.org/W1981877077', 'https://openalex.org/W1983137097', 'https://openalex.org/W1990913409', 'https://openalex.org/W1991662012', 'https://openalex.org/W1996847026', 'https://openalex.org/W2001879508', 'https://openalex.org/W2002042370', 'https://openalex.org/W2002422701', 'https://openalex.org/W2010900780', 'https://openalex.org/W2018409817', 'https://openalex.org/W2018840519', 'https://openalex.org/W2019973925', 'https://openalex.org/W2031468523', 'https://openalex.org/W2035424140', 'https://openalex.org/W2044779639', 'https://openalex.org/W2061334771', 'https://openalex.org/W2065148702', 'https://openalex.org/W2091470808', 'https://openalex.org/W2101310027', 'https://openalex.org/W2107618443', 'https://openalex.org/W2115160551', 'https://openalex.org/W2116616972', 'https://openalex.org/W2136759184', 'https://openalex.org/W2148701127', 'https://openalex.org/W2152115272', 'https://openalex.org/W2178057176', 'https://openalex.org/W2273943985', 'https://openalex.org/W2307595411', 'https://openalex.org/W2339521230', 'https://openalex.org/W2401737803', 'https://openalex.org/W2415168605', 'https://openalex.org/W2417313482', 'https://openalex.org/W93308564'], 'related_works': ['https://openalex.org/W580609289', 'https://openalex.org/W343153712', 'https://openalex.org/W3175002232', 'https://openalex.org/W30141755', 'https://openalex.org/W2985640214', 'https://openalex.org/W2499467363', 'https://openalex.org/W2319735687', 'https://openalex.org/W2175739831', 'https://openalex.org/W2137696524', 'https://openalex.org/W2100787917'], 'abstract_inverted_index': None, 'abstract_inverted_index_v3': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2065847009', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2025-01-25T22:42:09.046516', 'created_date': '2016-06-24'}