Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2065699789', 'doi': 'https://doi.org/10.1021/bi001416s', 'title': 'The Active Site Structure of <i>Thalassiosira weissflogii </i>Carbonic Anhydrase 1', 'display_name': 'The Active Site Structure of <i>Thalassiosira weissflogii </i>Carbonic Anhydrase 1', 'publication_year': 2000, 'publication_date': '2000-09-13', 'ids': {'openalex': 'https://openalex.org/W2065699789', 'doi': 'https://doi.org/10.1021/bi001416s', 'mag': '2065699789', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11015190'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi001416s', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5042148058', 'display_name': 'E C Cox', 'orcid': 'https://orcid.org/0000-0003-0467-6609'}, 'institutions': [{'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Elizabeth H. Cox', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I4210120900', 'https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I20089843']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072963758', 'display_name': 'George McLendon', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'George L. McLendon', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I4210120900', 'https://openalex.org/I20089843']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066620798', 'display_name': 'François M. M. Morel', 'orcid': 'https://orcid.org/0000-0002-6311-7826'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'François M. M. Morel', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I4210120900', 'https://openalex.org/I20089843']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041106553', 'display_name': 'Todd W. Lane', 'orcid': 'https://orcid.org/0000-0002-5816-2649'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Todd W. Lane', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I4210120900', 'https://openalex.org/I20089843']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027466445', 'display_name': 'Roger C. Prince', 'orcid': 'https://orcid.org/0000-0002-5174-4216'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Roger C. Prince', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I4210120900', 'https://openalex.org/I20089843']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028738166', 'display_name': 'Ingrid J. Pickering', 'orcid': 'https://orcid.org/0000-0002-0936-2994'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ingrid J. Pickering', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I4210120900', 'https://openalex.org/I20089843']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058639044', 'display_name': 'Graham N. George', 'orcid': 'https://orcid.org/0000-0002-0420-7493'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I923382979', 'display_name': 'ExxonMobil (United States)', 'ror': 'https://ror.org/01xcepn55', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I923382979']}, {'id': 'https://openalex.org/I4210120900', 'display_name': 'Stanford Synchrotron Radiation Lightsource', 'ror': 'https://ror.org/02vzbm991', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1330989302', 'https://openalex.org/I2801935854', 'https://openalex.org/I39565521', 'https://openalex.org/I4210120900', 'https://openalex.org/I97018004']}, {'id': 'https://openalex.org/I20089843', 'display_name': 'Princeton University', 'ror': 'https://ror.org/00hx57361', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I20089843']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Graham N. George', 'raw_affiliation_strings': ['Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309'], 'affiliations': [{'raw_affiliation_string': 'Center for Environmental Bioinorganic Chemistry, Departments of Chemistry and Geosciences, Princeton University, Princeton, New Jersey 08544, ExxonMobil Research and Engineering Company, Annandale, New Jersey 08801, and Stanford Synchrotron Radiation Laboratory, SLAC, Stanford University, P.O. Box 20450, MS 69, Stanford, California 94309', 'institution_ids': ['https://openalex.org/I97018004', 'https://openalex.org/I923382979', 'https://openalex.org/I4210120900', 'https://openalex.org/I20089843']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.287, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 115, 'citation_normalized_percentile': {'value': 0.951172, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '39', 'issue': '40', 'first_page': '12128', 'last_page': '12130'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12412', 'display_name': 'Role of Carbonic Anhydrases in Medicine and Biotechnology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12412', 'display_name': 'Role of Carbonic Anhydrases in Medicine and Biotechnology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11924', 'display_name': 'Polyamines and Biogenic Amines in Biology and Health', 'score': 0.9601, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11626', 'display_name': 'Biological and Synthetic Hydrogenases: Mechanisms and Applications', 'score': 0.9551, 'subfield': {'id': 'https://openalex.org/subfields/2105', 'display_name': 'Renewable Energy, Sustainability and the Environment'}, 'field': {'id': 'https://openalex.org/fields/21', 'display_name': 'Energy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thalassiosira-weissflogii', 'display_name': 'Thalassiosira weissflogii', 'score': 0.62904453}, {'id': 'https://openalex.org/keywords/carbonic-anhydrases', 'display_name': 'Carbonic Anhydrases', 'score': 0.553311}, {'id': 'https://openalex.org/keywords/carbonic-anhydrase-ii', 'display_name': 'Carbonic anhydrase II', 'score': 0.5050171}], 'concepts': [{'id': 'https://openalex.org/C2775914622', 'wikidata': 'https://www.wikidata.org/wiki/Q284089', 'display_name': 'Carbonic anhydrase', 'level': 3, 'score': 0.9273189}, {'id': 'https://openalex.org/C41183919', 'wikidata': 'https://www.wikidata.org/wiki/Q423026', 'display_name': 'Active site', 'level': 3, 'score': 0.6550098}, {'id': 'https://openalex.org/C2778460671', 'wikidata': 'https://www.wikidata.org/wiki/Q485277', 'display_name': 'Histidine', 'level': 3, 'score': 0.6508767}, {'id': 'https://openalex.org/C2779673048', 'wikidata': 'https://www.wikidata.org/wiki/Q16993037', 'display_name': 'Thalassiosira weissflogii', 'level': 4, 'score': 0.62904453}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6143443}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.55663496}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.5177447}, {'id': 'https://openalex.org/C2780416268', 'wikidata': 'https://www.wikidata.org/wiki/Q18021049', 'display_name': 'Carbonic anhydrase II', 'level': 4, 'score': 0.5050171}, {'id': 'https://openalex.org/C535196362', 'wikidata': 'https://www.wikidata.org/wiki/Q758', 'display_name': 'Zinc', 'level': 2, 'score': 0.45205563}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.06741303}, {'id': 'https://openalex.org/C2780892065', 'wikidata': 'https://www.wikidata.org/wiki/Q184755', 'display_name': 'Phytoplankton', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C142796444', 'wikidata': 'https://www.wikidata.org/wiki/Q181394', 'display_name': 'Nutrient', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002256', 'descriptor_name': 'Carbonic Anhydrases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D002256', 'descriptor_name': 'Carbonic Anhydrases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017377', 'descriptor_name': 'Diatoms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002256', 'descriptor_name': 'Carbonic Anhydrases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002417', 'descriptor_name': 'Cattle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017377', 'descriptor_name': 'Diatoms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005583', 'descriptor_name': 'Fourier Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012542', 'descriptor_name': 'Scattering, Radiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013057', 'descriptor_name': 'Spectrum Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018724', 'descriptor_name': 'Spinacia oleracea', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D018724', 'descriptor_name': 'Spinacia oleracea', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014965', 'descriptor_name': 'X-Rays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015032', 'descriptor_name': 'Zinc', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D015032', 'descriptor_name': 'Zinc', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015032', 'descriptor_name': 'Zinc', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi001416s', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11015190', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life below water', 'score': 0.89, 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 8, 'referenced_works': ['https://openalex.org/W1540876114', 'https://openalex.org/W1823556928', 'https://openalex.org/W1975763169', 'https://openalex.org/W1984907902', 'https://openalex.org/W1992220816', 'https://openalex.org/W2035046825', 'https://openalex.org/W2078000104', 'https://openalex.org/W2103210188'], 'related_works': ['https://openalex.org/W3207131410', 'https://openalex.org/W3178245966', 'https://openalex.org/W2588869820', 'https://openalex.org/W2172288068', 'https://openalex.org/W2072464466', 'https://openalex.org/W2065007096', 'https://openalex.org/W2020142163', 'https://openalex.org/W1991900549', 'https://openalex.org/W1978474786', 'https://openalex.org/W1969599525'], 'abstract_inverted_index': {'X-ray': [0], 'absorption': [1], 'spectroscopy': [2], 'at': [3, 40, 90], 'the': [4, 9, 13, 48, 91], 'Zn': [5], 'K-edge': [6], 'indicates': [7], 'that': [8, 24], 'active': [10], 'site': [11], 'of': [12, 25, 51, 87], 'marine': [14], 'diatom': [15, 70], 'Thalassiosira': [16], 'weissflogii': [17], 'carbonic': [18, 71, 80], 'anhydrase': [19, 28, 72], 'is': [20, 44, 57], 'strikingly': [21], 'similar': [22], 'to': [23], 'mammalian': [26], 'α-carbonic': [27], 'enzymes.': [29], 'The': [30, 69], 'zinc': [31, 56], 'has': [32], 'three': [33], 'histidine': [34], 'ligands': [35], 'and': [36, 65, 82], 'a': [37, 66], 'single': [38], 'water': [39, 67], '1.98': [41], 'Å.': [42], 'This': [43], 'quite': [45], 'different': [46], 'from': [47], 'β-carbonic': [49], 'anhydrases': [50, 81], 'higher': [52], 'plants': [53], 'in': [54], 'which': [55], 'coordinated': [58], 'by': [59], 'two': [60], 'cysteine': [61], 'thiolates,': [62], 'one': [63], 'histidine,': [64], 'molecule.': [68], 'shows': [73], 'no': [74], 'significant': [75], 'sequence': [76], 'similarity': [77], 'with': [78], 'other': [79], 'may': [83], 'represent': [84], 'an': [85], 'example': [86], 'convergent': [88], 'evolution': [89], 'molecular': [92], 'level.': [93]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2065699789', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-08-27T22:41:51.130288', 'created_date': '2016-06-24'}