Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2065385356', 'doi': 'https://doi.org/10.1016/s0958-1669(02)00279-3', 'title': 'Metabolomics and microarrays for improved understanding of phenotypic characteristics controlled by both genomics and environmental constraints', 'display_name': 'Metabolomics and microarrays for improved understanding of phenotypic characteristics controlled by both genomics and environmental constraints', 'publication_year': 2002, 'publication_date': '2002-02-01', 'ids': {'openalex': 'https://openalex.org/W2065385356', 'doi': 'https://doi.org/10.1016/s0958-1669(02)00279-3', 'mag': '2065385356', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11849953'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0958-1669(02)00279-3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S23939942', 'display_name': 'Current Opinion in Biotechnology', 'issn_l': '0958-1669', 'issn': ['0958-1669', '1879-0429'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5034666752', 'display_name': 'Tommy J. Phelps', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289243028', 'display_name': 'Oak Ridge National Laboratory', 'ror': 'https://ror.org/01qz5mb56', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289243028', 'https://openalex.org/I1330989302', 'https://openalex.org/I39565521', 'https://openalex.org/I4210159294']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tommy J Phelps', 'raw_affiliation_strings': ['Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6038, USA'], 'affiliations': [{'raw_affiliation_string': 'Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6038, USA', 'institution_ids': ['https://openalex.org/I1289243028']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049270295', 'display_name': 'Anthony V. Palumbo', 'orcid': 'https://orcid.org/0000-0002-1102-3975'}, 'institutions': [{'id': 'https://openalex.org/I1289243028', 'display_name': 'Oak Ridge National Laboratory', 'ror': 'https://ror.org/01qz5mb56', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289243028', 'https://openalex.org/I1330989302', 'https://openalex.org/I39565521', 'https://openalex.org/I4210159294']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anthony V Palumbo', 'raw_affiliation_strings': ['Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6038, USA'], 'affiliations': [{'raw_affiliation_string': 'Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6038, USA', 'institution_ids': ['https://openalex.org/I1289243028']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060699453', 'display_name': 'Alex Beliaev', 'orcid': 'https://orcid.org/0000-0002-6766-4632'}, 'institutions': [{'id': 'https://openalex.org/I1289243028', 'display_name': 'Oak Ridge National Laboratory', 'ror': 'https://ror.org/01qz5mb56', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289243028', 'https://openalex.org/I1330989302', 'https://openalex.org/I39565521', 'https://openalex.org/I4210159294']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alex S Beliaev', 'raw_affiliation_strings': ['Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6038, USA'], 'affiliations': [{'raw_affiliation_string': 'Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6038, USA', 'institution_ids': ['https://openalex.org/I1289243028']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4890, 'currency': 'USD', 'value_usd': 4890, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.641, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 90, 'citation_normalized_percentile': {'value': 0.669123, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '13', 'issue': '1', 'first_page': '20', 'last_page': '24'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10836', 'display_name': 'Advances in Metabolomics Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10836', 'display_name': 'Advances in Metabolomics Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10885', 'display_name': 'Microarray Data Analysis and Gene Expression Profiling', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11970', 'display_name': 'Real-Time Polymerase Chain Reaction', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/functional-genomics', 'display_name': 'Functional genomics', 'score': 0.6412504}, {'id': 'https://openalex.org/keywords/metabolomics', 'display_name': 'Metabolomics', 'score': 0.563994}, {'id': 'https://openalex.org/keywords/genomics', 'display_name': 'Genomics', 'score': 0.526442}, {'id': 'https://openalex.org/keywords/pharmacometabolomics', 'display_name': 'Pharmacometabolomics', 'score': 0.512213}, {'id': 'https://openalex.org/keywords/profiling', 'display_name': 'Profiling (computer programming)', 'score': 0.45443127}], 'concepts': [{'id': 'https://openalex.org/C21565614', 'wikidata': 'https://www.wikidata.org/wiki/Q12149006', 'display_name': 'Metabolomics', 'level': 2, 'score': 0.7808892}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.7170831}, {'id': 'https://openalex.org/C189206191', 'wikidata': 'https://www.wikidata.org/wiki/Q222046', 'display_name': 'Genomics', 'level': 4, 'score': 0.68559265}, {'id': 'https://openalex.org/C161078062', 'wikidata': 'https://www.wikidata.org/wiki/Q1068690', 'display_name': 'Functional genomics', 'level': 5, 'score': 0.6412504}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5958729}, {'id': 'https://openalex.org/C95371953', 'wikidata': 'https://www.wikidata.org/wiki/Q591745', 'display_name': 'DNA microarray', 'level': 4, 'score': 0.59580815}, {'id': 'https://openalex.org/C46111723', 'wikidata': 'https://www.wikidata.org/wiki/Q471857', 'display_name': 'Proteomics', 'level': 3, 'score': 0.5686465}, {'id': 'https://openalex.org/C187191949', 'wikidata': 'https://www.wikidata.org/wiki/Q1138496', 'display_name': 'Profiling (computer programming)', 'level': 2, 'score': 0.45443127}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.44932514}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.42911676}, {'id': 'https://openalex.org/C18431079', 'wikidata': 'https://www.wikidata.org/wiki/Q1502169', 'display_name': 'Gene expression profiling', 'level': 4, 'score': 0.4252369}, {'id': 'https://openalex.org/C14036430', 'wikidata': 'https://www.wikidata.org/wiki/Q3736076', 'display_name': 'Function (biology)', 'level': 2, 'score': 0.41182125}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.35270217}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.34760094}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.33817124}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2559545}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.16153193}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020412', 'descriptor_name': 'Multifactorial Inheritance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002250', 'descriptor_name': 'Carbon Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004777', 'descriptor_name': 'Environment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008401', 'descriptor_name': 'Gas Chromatography-Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009682', 'descriptor_name': 'Magnetic Resonance Spectroscopy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0958-1669(02)00279-3', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S23939942', 'display_name': 'Current Opinion in Biotechnology', 'issn_l': '0958-1669', 'issn': ['0958-1669', '1879-0429'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11849953', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Responsible consumption and production', 'score': 0.42, 'id': 'https://metadata.un.org/sdg/12'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W1491527738', 'https://openalex.org/W1549912426', 'https://openalex.org/W1865440815', 'https://openalex.org/W1894848931', 'https://openalex.org/W1914762032', 'https://openalex.org/W1964227455', 'https://openalex.org/W1965321163', 'https://openalex.org/W1966302864', 'https://openalex.org/W1970152947', 'https://openalex.org/W1971649516', 'https://openalex.org/W1979335383', 'https://openalex.org/W1989845358', 'https://openalex.org/W1999234724', 'https://openalex.org/W1999830094', 'https://openalex.org/W2006062850', 'https://openalex.org/W2013947082', 'https://openalex.org/W2030309374', 'https://openalex.org/W2034354682', 'https://openalex.org/W2041183456', 'https://openalex.org/W2049167322', 'https://openalex.org/W2050161149', 'https://openalex.org/W2057134455', 'https://openalex.org/W2059918229', 'https://openalex.org/W2068728888', 'https://openalex.org/W2069271664', 'https://openalex.org/W2080760786', 'https://openalex.org/W2082920045', 'https://openalex.org/W2085662298', 'https://openalex.org/W2088836626', 'https://openalex.org/W2092265987', 'https://openalex.org/W2099245280', 'https://openalex.org/W2103453943', 'https://openalex.org/W2104140801', 'https://openalex.org/W2113310577', 'https://openalex.org/W2120714068', 'https://openalex.org/W2126821981', 'https://openalex.org/W2132809900', 'https://openalex.org/W2134483262', 'https://openalex.org/W2146789938', 'https://openalex.org/W2147454875', 'https://openalex.org/W2151727574', 'https://openalex.org/W2162314707', 'https://openalex.org/W2162621033', 'https://openalex.org/W2163388517', 'https://openalex.org/W2165762336', 'https://openalex.org/W2167945159', 'https://openalex.org/W2168846334', 'https://openalex.org/W2769081716', 'https://openalex.org/W4206594368', 'https://openalex.org/W4240842438', 'https://openalex.org/W4248959400', 'https://openalex.org/W643275671'], 'related_works': ['https://openalex.org/W3032874291', 'https://openalex.org/W2419660104', 'https://openalex.org/W2416004817', 'https://openalex.org/W2261819947', 'https://openalex.org/W2158455641', 'https://openalex.org/W2134884997', 'https://openalex.org/W2065385356', 'https://openalex.org/W2039940120', 'https://openalex.org/W2009365322', 'https://openalex.org/W2007091097'], 'abstract_inverted_index': {'Advances': [0], 'in': [1, 81], 'our': [2], 'understanding': [3], 'of': [4, 16, 55, 84], 'functional': [5], 'genomics': [6], 'are': [7], 'best': [8], 'addressed': [9], 'by': [10], 'integrative': [11], 'studies': [12], 'that': [13], 'include': [14], 'measurements': [15], 'mRNA,': [17], 'proteins,': [18], 'and': [19, 26, 46, 51, 60, 77], 'low': [20, 56], 'molecular': [21, 57], 'weight': [22, 58], 'metabolites': [23], 'over': [24], 'time': [25], 'varied': [27], 'conditions.': [28], 'Bioinformatics': [29], 'can': [30], 'then': [31], 'be': [32], 'used': [33], 'to': [34, 38], 'relate': [35], 'this': [36, 66], 'data': [37], 'the': [39, 82], 'genome.': [40], 'Current': [41], 'technology': [42], 'allows': [43], 'for': [44, 73], 'comprehensive': [45], 'rapid': [47], 'mRNA': [48], 'expression': [49], 'profiling': [50], 'mass': [52], 'spectrophotometric': [53], 'measurement': [54], 'intermediates': [59], 'metabolic': [61], 'products.': [62], 'In': [63], 'prokaryotic': [64], 'organisms,': [65], 'combination': [67], 'provides': [68], 'a': [69, 85], 'potentially': [70], 'powerful': [71], 'tool': [72], 'identifying': [74], 'gene': [75], 'function': [76], 'regulatory': [78], 'networks': [79], 'even': [80], 'absence': [83], 'combined': [86], 'proteomic': [87], 'approach.': [88]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2065385356', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-08-15T07:58:09.653451', 'created_date': '2016-06-24'}