Effects of γ2S subunit incorporation on GABAA receptor macroscopic kinetics

Name: Work Video:
Duration: 3 min 30 s
Andrew J. Boileau; T. Li; Claudia Benkwitz; Cynthia Czajkowski; Robert A. Pearce
{'id': 'https://openalex.org/W2064354423', 'doi': 'https://doi.org/10.1016/s0028-3908(03)00114-x', 'title': 'Effects of γ2S subunit incorporation on GABAA receptor macroscopic kinetics', 'display_name': 'Effects of γ2S subunit incorporation on GABAA receptor macroscopic kinetics', 'publication_year': 2003, 'publication_date': '2003-05-19', 'ids': {'openalex': 'https://openalex.org/W2064354423', 'doi': 'https://doi.org/10.1016/s0028-3908(03)00114-x', 'mag': '2064354423', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12763093'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0028-3908(03)00114-x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S160566677', 'display_name': 'Neuropharmacology', 'issn_l': '0028-3908', 'issn': ['0028-3908', '1873-7064'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081025343', 'display_name': 'Andrew J. Boileau', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'A.J. Boileau', 'raw_affiliation_strings': ['Department of Physiology, University of Wisconsin, Madison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075057331', 'display_name': 'T. Li', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T. Li', 'raw_affiliation_strings': ['Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026367002', 'display_name': 'Claudia Benkwitz', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C. Benkwitz', 'raw_affiliation_strings': ['Department of Anesthesiology, University of Wisconsin, Madison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079209684', 'display_name': 'Cynthia Czajkowski', 'orcid': 'https://orcid.org/0000-0002-4578-3964'}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C. Czajkowski', 'raw_affiliation_strings': ['Department of Physiology, University of Wisconsin, Madison, WI 53706, USA', 'Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}, {'raw_affiliation_string': 'Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5087838557', 'display_name': 'Robert A. Pearce', 'orcid': 'https://orcid.org/0000-0002-1516-6260'}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'R.A. Pearce', 'raw_affiliation_strings': ['Department of Anatomy, University of Wisconsin, Madison, WI 53706, USA', 'Department of Anesthesiology, University of Wisconsin, Madison, WI 53706, USA', 'Department of Physiology, University of Wisconsin, Madison, WI 53706, USA', 'Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}, {'raw_affiliation_string': 'Department of Anesthesiology, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}, {'raw_affiliation_string': 'Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}, {'raw_affiliation_string': 'Department of Physiology, University of Wisconsin, Madison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5087838557'], 'corresponding_institution_ids': ['https://openalex.org/I135310074'], 'apc_list': {'value': 4050, 'currency': 'USD', 'value_usd': 4050, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.127, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 56, 'citation_normalized_percentile': {'value': 0.708107, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '44', 'issue': '8', 'first_page': '1003', 'last_page': '1012'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/gabaa-rho-receptor', 'display_name': 'GABAA-rho receptor', 'score': 0.7337493}, {'id': 'https://openalex.org/keywords/cys-loop-receptors', 'display_name': 'Cys-loop receptors', 'score': 0.62483466}, {'id': 'https://openalex.org/keywords/class-c-gpcr', 'display_name': 'Class C GPCR', 'score': 0.4974256}, {'id': 'https://openalex.org/keywords/hek-293-cells', 'display_name': 'HEK 293 cells', 'score': 0.45375252}], 'concepts': [{'id': 'https://openalex.org/C168258287', 'wikidata': 'https://www.wikidata.org/wiki/Q60147', 'display_name': 'GABAA receptor', 'level': 3, 'score': 0.8944992}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.78901005}, {'id': 'https://openalex.org/C9224880', 'wikidata': 'https://www.wikidata.org/wiki/Q798179', 'display_name': 'GABAA-rho receptor', 'level': 4, 'score': 0.7337493}, {'id': 'https://openalex.org/C104292427', 'wikidata': 'https://www.wikidata.org/wiki/Q899781', 'display_name': 'Protein subunit', 'level': 3, 'score': 0.67745006}, {'id': 'https://openalex.org/C2779779143', 'wikidata': 'https://www.wikidata.org/wiki/Q3493547', 'display_name': 'Desensitization (medicine)', 'level': 3, 'score': 0.6274295}, {'id': 'https://openalex.org/C19876734', 'wikidata': 'https://www.wikidata.org/wiki/Q5201170', 'display_name': 'Cys-loop receptors', 'level': 5, 'score': 0.62483466}, {'id': 'https://openalex.org/C2779535977', 'wikidata': 'https://www.wikidata.org/wiki/Q1342298', 'display_name': 'Xenopus', 'level': 3, 'score': 0.5903205}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5192854}, {'id': 'https://openalex.org/C203270574', 'wikidata': 'https://www.wikidata.org/wiki/Q24725121', 'display_name': 'Class C GPCR', 'level': 5, 'score': 0.4974256}, {'id': 'https://openalex.org/C17077164', 'wikidata': 'https://www.wikidata.org/wiki/Q1185869', 'display_name': 'Inhibitory postsynaptic potential', 'level': 2, 'score': 0.4838211}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.45957327}, {'id': 'https://openalex.org/C174510640', 'wikidata': 'https://www.wikidata.org/wiki/Q489618', 'display_name': 'HEK 293 cells', 'level': 3, 'score': 0.45375252}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.43869126}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41896874}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.3093965}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.29593843}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.2507379}, {'id': 'https://openalex.org/C80161118', 'wikidata': 'https://www.wikidata.org/wiki/Q408520', 'display_name': 'Acetylcholine receptor', 'level': 3, 'score': 0.18909734}, {'id': 'https://openalex.org/C26702167', 'wikidata': 'https://www.wikidata.org/wiki/Q901988', 'display_name': 'Metabotropic receptor', 'level': 4, 'score': 0.13356933}, {'id': 'https://openalex.org/C2779570518', 'wikidata': 'https://www.wikidata.org/wiki/Q412256', 'display_name': 'Nicotinic acetylcholine receptor', 'level': 4, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D011963', 'descriptor_name': 'Receptors, GABA-A', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018408', 'descriptor_name': 'Patch-Clamp Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021122', 'descriptor_name': 'Protein Subunits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021122', 'descriptor_name': 'Protein Subunits', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011963', 'descriptor_name': 'Receptors, GABA-A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0028-3908(03)00114-x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S160566677', 'display_name': 'Neuropharmacology', 'issn_l': '0028-3908', 'issn': ['0028-3908', '1873-7064'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12763093', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1482497049', 'https://openalex.org/W1504992746', 'https://openalex.org/W1538927534', 'https://openalex.org/W1550693429', 'https://openalex.org/W1595197310', 'https://openalex.org/W1684501056', 'https://openalex.org/W1748513738', 'https://openalex.org/W1798308120', 'https://openalex.org/W1827031147', 'https://openalex.org/W1846189485', 'https://openalex.org/W1941659122', 'https://openalex.org/W1971170321', 'https://openalex.org/W1973238622', 'https://openalex.org/W1985024007', 'https://openalex.org/W1990761201', 'https://openalex.org/W1991847312', 'https://openalex.org/W1993095599', 'https://openalex.org/W1994261508', 'https://openalex.org/W2001173861', 'https://openalex.org/W2007262222', 'https://openalex.org/W2015236121', 'https://openalex.org/W2022378061', 'https://openalex.org/W2023468172', 'https://openalex.org/W2029291515', 'https://openalex.org/W2033801272', 'https://openalex.org/W2041203007', 'https://openalex.org/W2043385322', 'https://openalex.org/W2044669542', 'https://openalex.org/W2066232912', 'https://openalex.org/W2067237230', 'https://openalex.org/W2068375642', 'https://openalex.org/W2079319779', 'https://openalex.org/W2083793877', 'https://openalex.org/W2089518161', 'https://openalex.org/W2099883420', 'https://openalex.org/W2118922355', 'https://openalex.org/W2123606404', 'https://openalex.org/W2129842868', 'https://openalex.org/W2131645763', 'https://openalex.org/W2136786332', 'https://openalex.org/W2139773174', 'https://openalex.org/W2143252669', 'https://openalex.org/W2162666247', 'https://openalex.org/W2222229019', 'https://openalex.org/W2225745550', 'https://openalex.org/W2341270633', 'https://openalex.org/W2343819992', 'https://openalex.org/W2407931818', 'https://openalex.org/W2410908424', 'https://openalex.org/W2415545141', 'https://openalex.org/W2443450049', 'https://openalex.org/W303540388', 'https://openalex.org/W4317707744', 'https://openalex.org/W77926042'], 'related_works': ['https://openalex.org/W4242690077', 'https://openalex.org/W2803898079', 'https://openalex.org/W2322979411', 'https://openalex.org/W2084480455', 'https://openalex.org/W2046755082', 'https://openalex.org/W2010231019', 'https://openalex.org/W1992589532', 'https://openalex.org/W1977647232', 'https://openalex.org/W1975539866', 'https://openalex.org/W1973557083'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2064354423', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-10T15:50:39.409593', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
