Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2063781606', 'doi': 'https://doi.org/10.1016/j.toxlet.2014.05.005', 'title': 'miR-21 regulates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2', 'display_name': 'miR-21 regulates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2', 'publication_year': 2014, 'publication_date': '2014-08-01', 'ids': {'openalex': 'https://openalex.org/W2063781606', 'doi': 'https://doi.org/10.1016/j.toxlet.2014.05.005', 'mag': '2063781606', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24821435'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.toxlet.2014.05.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S205878144', 'display_name': 'Toxicology Letters', 'issn_l': '0378-4274', 'issn': ['0378-4274', '1879-3169'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057791401', 'display_name': 'Qiaoyuan Yang', 'orcid': 'https://orcid.org/0000-0003-1720-9057'}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qiaoyuan Yang', 'raw_affiliation_strings': ['Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China'], 'affiliations': [{'raw_affiliation_string': 'Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050646003', 'display_name': 'Enwu Xu', 'orcid': 'https://orcid.org/0000-0003-2596-2030'}, 'institutions': [{'id': 'https://openalex.org/I4210099466', 'display_name': 'General Hospital of Guangzhou Military Command', 'ror': 'https://ror.org/00hfbva78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210099466']}, {'id': 'https://openalex.org/I4210160531', 'display_name': "Chinese People's Liberation Army", 'ror': 'https://ror.org/05tf9r976', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I4210160531']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Enwu Xu', 'raw_affiliation_strings': ["Department of Thoracic Surgery, General Hospital of Guangzhou Military Command of Chinese People's Liberation Army, Guangzhou 510010, PR China"], 'affiliations': [{'raw_affiliation_string': "Department of Thoracic Surgery, General Hospital of Guangzhou Military Command of Chinese People's Liberation Army, Guangzhou 510010, PR China", 'institution_ids': ['https://openalex.org/I4210099466', 'https://openalex.org/I4210160531']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023601320', 'display_name': 'Jiabin Dai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiabin Dai', 'raw_affiliation_strings': ['Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China'], 'affiliations': [{'raw_affiliation_string': 'Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100599435', 'display_name': 'Jian Wu', 'orcid': 'https://orcid.org/0000-0002-3394-1507'}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianjun Wu', 'raw_affiliation_strings': ['Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China'], 'affiliations': [{'raw_affiliation_string': 'Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043826855', 'display_name': 'Shaozhu Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shaozhu Zhang', 'raw_affiliation_strings': ['Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China'], 'affiliations': [{'raw_affiliation_string': 'Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048143687', 'display_name': 'Baoying Peng', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Baoying Peng', 'raw_affiliation_strings': ['Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China'], 'affiliations': [{'raw_affiliation_string': 'Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010427741', 'display_name': 'Yiguo Jiang', 'orcid': 'https://orcid.org/0000-0002-9499-2594'}, 'institutions': [{'id': 'https://openalex.org/I4210154954', 'display_name': 'State Key Laboratory of Respiratory Disease', 'ror': 'https://ror.org/04hja5e04', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154954']}, {'id': 'https://openalex.org/I92039509', 'display_name': 'Guangzhou Medical University', 'ror': 'https://ror.org/00zat6v61', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I92039509']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yiguo Jiang', 'raw_affiliation_strings': ['Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China'], 'affiliations': [{'raw_affiliation_string': 'Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510182, PR China', 'institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5010427741'], 'corresponding_institution_ids': ['https://openalex.org/I4210154954', 'https://openalex.org/I92039509'], 'apc_list': {'value': 3990, 'currency': 'USD', 'value_usd': 3990, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.509, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 40, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '228', 'issue': '3', 'first_page': '147', 'last_page': '156'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13157', 'display_name': 'Protein Arginine Methylation in Mammals', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13157', 'display_name': 'Protein Arginine Methylation in Mammals', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/arginine-methylation', 'display_name': 'Arginine Methylation', 'score': 0.482742}], 'concepts': [{'id': 'https://openalex.org/C555283112', 'wikidata': 'https://www.wikidata.org/wiki/Q1637543', 'display_name': 'Carcinogenesis', 'level': 3, 'score': 0.9443042}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.7135905}, {'id': 'https://openalex.org/C114246631', 'wikidata': 'https://www.wikidata.org/wiki/Q187661', 'display_name': 'Carcinogen', 'level': 2, 'score': 0.70483416}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.6137743}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53322846}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.34453002}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2788586}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2158233}], 'mesh': [{'descriptor_ui': 'D002273', 'descriptor_name': 'Carcinogens', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D053222', 'descriptor_name': 'Fas Ligand Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017874', 'descriptor_name': 'Immediate-Early Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008769', 'descriptor_name': 'Methylnitronitrosoguanidine', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D025521', 'descriptor_name': 'Tumor Suppressor Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020413', 'descriptor_name': "3' Untranslated Regions", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002273', 'descriptor_name': 'Carcinogens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053222', 'descriptor_name': 'Fas Ligand Protein', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D053222', 'descriptor_name': 'Fas Ligand Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055785', 'descriptor_name': 'Gene Knockdown Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017874', 'descriptor_name': 'Immediate-Early Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017874', 'descriptor_name': 'Immediate-Early Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008769', 'descriptor_name': 'Methylnitronitrosoguanidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025521', 'descriptor_name': 'Tumor Suppressor Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D025521', 'descriptor_name': 'Tumor Suppressor Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.toxlet.2014.05.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S205878144', 'display_name': 'Toxicology Letters', 'issn_l': '0378-4274', 'issn': ['0378-4274', '1879-3169'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24821435', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1509359211', 'https://openalex.org/W1557444671', 'https://openalex.org/W1963640511', 'https://openalex.org/W1968582610', 'https://openalex.org/W1969495433', 'https://openalex.org/W1978561866', 'https://openalex.org/W1983392124', 'https://openalex.org/W1987021965', 'https://openalex.org/W1994517596', 'https://openalex.org/W1996479975', 'https://openalex.org/W1999360191', 'https://openalex.org/W2000093333', 'https://openalex.org/W2008594130', 'https://openalex.org/W2008955962', 'https://openalex.org/W2014946489', 'https://openalex.org/W2016414952', 'https://openalex.org/W2019268693', 'https://openalex.org/W2028164074', 'https://openalex.org/W2038786311', 'https://openalex.org/W2046240292', 'https://openalex.org/W2050079849', 'https://openalex.org/W2059978499', 'https://openalex.org/W2061245152', 'https://openalex.org/W2069104846', 'https://openalex.org/W2075258024', 'https://openalex.org/W2076237302', 'https://openalex.org/W2081879088', 'https://openalex.org/W2097416376', 'https://openalex.org/W2101406042', 'https://openalex.org/W2101465187', 'https://openalex.org/W2112785261', 'https://openalex.org/W2112880435', 'https://openalex.org/W2112916657', 'https://openalex.org/W2123266023', 'https://openalex.org/W2126532720', 'https://openalex.org/W2131597845', 'https://openalex.org/W2132834292', 'https://openalex.org/W2135810600', 'https://openalex.org/W2140481064', 'https://openalex.org/W2142709908', 'https://openalex.org/W2144872854', 'https://openalex.org/W2148417110', 'https://openalex.org/W2150536104', 'https://openalex.org/W2398046266', 'https://openalex.org/W4237011200'], 'related_works': ['https://openalex.org/W3144241576', 'https://openalex.org/W2443952664', 'https://openalex.org/W2416560908', 'https://openalex.org/W2113725788', 'https://openalex.org/W2042073451', 'https://openalex.org/W2041390973', 'https://openalex.org/W2030108052', 'https://openalex.org/W1998898023', 'https://openalex.org/W1988174701', 'https://openalex.org/W161652093'], 'abstract_inverted_index': {'MicroRNAs': [0], '(miRNAs)': [1], 'are': [2, 10, 26], 'recently': [3], 'discovered': [4], 'regulators': [5], 'of': [6, 15, 52, 61, 111, 172, 183, 193], 'gene': [7, 133], 'expression': [8, 85], 'and': [9, 80, 99, 117, 130, 165, 188], 'important': [11], 'in': [12, 39, 63, 83, 96, 113, 146, 160, 163, 166, 185], 'the': [13, 34, 40, 58, 64, 70, 100, 109, 114, 126, 141, 151, 173, 180, 194], 'regulation': [14, 169], 'many': [16], 'cellular': [17], 'events.': [18], 'Evidence': [19], 'collected': [20], 'to': [21, 30, 56, 69, 140, 154], 'date': [22], 'shows': [23], 'that': [24, 36, 125, 156], 'miRNAs': [25, 184], 'altered': [27], 'after': [28], 'exposure': [29, 68], 'environmental': [31, 45], 'toxicants.': [32], 'However,': [33], 'role': [35, 60], 'miR-21': [37, 62, 84, 91, 112, 157, 171], 'plays': [38], 'gastric': [41, 101, 174], 'tumorigenesis': [42, 102, 118], 'induced': [43, 103, 143, 176], 'by': [44, 120, 137, 144, 170, 177], 'carcinogens': [46], 'remains': [47], 'largely': [48], 'unknown.': [49], 'The': [50, 168], 'aim': [51], 'this': [53], 'study': [54, 153], 'was': [55], 'characterize': [57], 'regulatory': [59], 'carcinogenic': [65], 'processes': [66], 'following': [67, 86], 'N-nitroso': [71], 'carcinogen': [72], "N-methyl-N-nitro-N'-nitrosoguanidine": [73], '(MNNG).': [74], 'We': [75, 122], 'found': [76], 'a': [77, 190], 'progressive': [78], 'dose-': [79], 'time-dependent': [81], 'increase': [82], 'treatment': [87], 'with': [88, 104], 'MNNG.': [89, 105, 121], 'Dysregulated': [90], 'affected': [92], 'both': [93], 'cell': [94], 'growth': [95], 'GES-1': [97, 147], 'cells': [98], 'These': [106], 'data': [107], 'demonstrate': [108], 'involvement': [110], 'malignant': [115], 'transformation': [116, 142], 'activated': [119], 'also': [123], 'established': [124], 'Fas': [127], 'ligand': [128], '(FASLG)': [129], 'B-cell': [131], 'translocation': [132], '2': [134], '(BTG2),': [135], 'regulated': [136], 'miR-21,': [138], 'contribute': [139], 'MNNG': [145, 178], 'cells.': [148], 'This': [149], 'is': [150, 158], 'first': [152], 'show': [155], 'involved': [159], 'chemical': [161, 186, 197], 'carcinogenesis': [162, 175], 'vivo': [164], 'vitro.': [167], 'highlights': [179], 'functional': [181], 'roles': [182], 'carcinogenesis,': [187], 'offers': [189], 'new': [191], 'explanation': [192], 'mechanisms': [195], 'underlying': [196], 'carcinogenesis.': [198]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2063781606', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-08-13T12:38:08.702628', 'created_date': '2016-06-24'}