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2335, 2423, 2430, 2457, 2621, 2650, 2652, 2758, 2822, 2847], 'phosphorylation': [13, 295, 316, 393, 418, 463, 480, 497, 546, 775, 1187, 1297, 1444, 1482, 1597, 1630, 1765, 2047, 2112, 2381, 2651, 2684], 'connexin43': [15, 301, 957, 1128, 1299, 1388, 1409, 1446, 1484, 1596, 1632, 1701, 1767, 1793, 1930, 2007, 2116, 2242, 2387, 2536], 'are': [16, 1197, 1937], 'not': [17, 412, 477, 537, 1390, 2567], 'sufficient': [18, 390, 2565], 'for': [19, 60, 77, 92, 109, 142, 159, 174, 191, 391, 427, 565, 984, 1417, 1537, 1874, 1925, 2209, 2357, 2361, 2390, 2595], 'the': [20, 239, 249, 294, 356, 479, 495, 516, 522, 549, 566, 646, 679, 727, 779, 783, 985, 996, 1022, 1055, 1078, 1131, 1136, 1165, 1171, 1306, 1418, 1538, 1569, 1589, 1605, 1660, 1847, 1923, 1926, 1934, 2049, 2091, 2140, 2383, 2391, 2454, 2460, 2491, 2505, 2532, 2596, 2680, 2687, 2777], 'disruption': [21, 420, 448, 533, 1438, 1476, 1590], 'gap': [23, 275, 298, 805, 887, 1099, 1125, 1292, 1376, 1421, 1440, 1478, 1543, 1592, 1680, 1760, 1820, 1905, 1927, 1953, 2050, 2081, 2172, 2233, 2298, 2384, 2455, 2487, 2533, 2560, 2689, 2710, 2819], 'junctional': [24, 276, 299, 806, 1293, 1377, 1422, 1441, 1479, 1544, 1593, 1761, 1821, 1824, 1906, 1928, 1954, 2082, 2173, 2234, 2299, 2561, 2711, 2820], 'communication': [25, 277, 808, 927, 955, 1106, 1294, 1378, 1442, 1480, 1594, 1682, 1762, 1825, 1956, 2022, 2200, 2235, 2301, 2332, 2562, 2713, 2821], 'by': [26, 63, 80, 95, 112, 145, 162, 177, 194, 279, 293, 360, 484, 515, 521, 540, 685, 782, 856, 1074, 1235, 1338, 1347, 1379, 1447, 1633, 1637, 1795, 1878, 1939, 2146, 2202, 2238, 2306, 2428, 2714, 2761, 2783], 'platelet-derived': [27, 308, 647, 1448, 2362], 'growth': [28, 283, 309, 365, 648, 829, 1201, 1449, 1474, 1510, 1586, 1735, 1757, 1899, 2148, 2309, 2363, 2597, 2786, 2804], 'factor': [29, 310, 366, 649, 830, 1450, 1511, 1587, 1758, 2310, 2364, 2598], 'tetradecanoylphorbol': [31], 'acetate': [32], 'Mohammad': [33, 38, 115, 120], 'Z.': [34, 39, 116, 121], 'Hossain,': [35, 117], 'Corresponding': [36, 118], 'Author': [37, 119], 'Hossain': [40, 122, 1396, 1430, 1466, 2221], '[email': [41, 123], 'protected]': [42, 124], 'Molecular': [43, 71, 86, 103, 125, 153, 168, 185], 'Medicine,': [44, 49, 72, 87, 104, 126, 131, 154, 169, 186], 'Northwest': [45, 50, 73, 88, 105, 127, 132, 155, 170, 187], 'Hospital,': [46, 51, 74, 89, 106, 128, 133, 156, 171, 188], 'Seattle,': [47, 57, 75, 90, 107, 129, 139, 157, 172, 189], 'WashingtonMolecular': [48, 130], '120': [52, 134], 'Northgate': [53, 135], 'Plaza,': [54, 136], 'Suite': [55, 137], '230,': [56, 138], 'WA': [58, 140], '98125.Search': [59, 141], 'more': [61, 78, 93, 110, 143, 160, 175, 192], 'papers': [62, 79, 94, 111, 144, 161, 176, 193], 'this': [64, 81, 96, 113, 146, 163, 178, 195, 258], 'authorAjit': [65, 147], 'B.': [66, 69, 148, 151, 1841, 1919, 2017, 2639], 'Jagdale,': [67, 149], 'Ajit': [68, 150], 'Jagdale': [70, 152], 'WashingtonSearch': [76, 91, 108, 158, 173, 190], 'authorPeng': [82, 164], 'Ao,': [83, 165], 'Peng': [84, 166], 'Ao': [85, 167, 1432, 1468], 'authorAlton': [97, 179], 'L.': [98, 101, 180, 183, 642, 826], 'Boynton,': [99, 181], 'Alton': [100, 182], 'Boynton': [102, 184, 1434, 1470, 1753, 2158, 2405], 'author': [114, 196], 'First': [197], 'published:': [198], '26': [199], 'February': [200], '1999': [201, 578], 'https://doi.org/10.1002/(SICI)1097-4652(199904)179:1<87::AID-JCP11>3.0.CO;2-KCitations:': [202], '41AboutPDF': [203], 'ToolsRequest': [204], 'permissionExport': [205], 'citationAdd': [206], 'to': [207, 229, 252, 290, 494, 1164, 2780, 2830], 'favoritesTrack': [208], 'citation': [209], 'ShareShare': [210], 'Give': [211], 'accessShare': [212, 215], 'full': [213, 2496], 'text': [214], 'full-text': [216, 231, 255], 'accessPlease': [217], 'review': [218], 'our': [219, 381, 529], 'Terms': [220, 243], 'Conditions': [222, 245], 'Use': [224], 'check': [226], 'box': [227], 'below': [228, 251], 'share': [230, 253], 'version': [232, 256], 'article.I': [234], 'have': [235, 304], 'read': [236], 'accept': [238], 'Wiley': [240], 'Online': [241], 'Library': [242], 'UseShareable': [247], 'LinkUse': [248], 'link': [250], 'a': [254, 269, 297, 307, 399, 425, 436, 452, 467, 686, 695, 1348, 1534, 1557, 1699, 2029, 2206, 2312, 2785], 'article': [259], 'with': [260, 415, 432, 473, 478, 504, 725, 755, 1130, 1564, 1901, 1963, 2537, 2852], 'your': [261], 'friends': [262], 'colleagues.': [264], 'Learn': [265], 'more.Copy': [266], 'URL': [267], 'Share': [268], 'linkShare': [270], 'onEmailFacebookTwitterLinkedInRedditWechat': [271], 'Abstract': [272], 'Disruption': [273], '(GJC)': [278], 'various': [280], 'compounds,': [281], 'including': [282, 363], 'factors': [284], 'tumor': [286, 687, 1829, 2751], 'promoters,': [287], 'is': [288, 411, 536, 562, 653, 1072, 1206, 1389, 1635, 1706, 2236, 2388, 2593], 'believed': [289], 'be': [291, 513], 'modulated': [292], 'protein,': [300], '(Cx43).': [302], 'We': [303], 'previously': [305], 'demonstrated': [306], '(PDGF)–induced': [311], 'blockade': [312], 'GJC': [314, 359, 395, 465, 474, 501, 535], 'Cx43': [318, 392, 417, 462, 482, 496, 545, 886], 'in': [319, 355, 492, 612, 645, 655, 691, 812, 864, 890, 958, 1107, 1199, 1238, 1269, 1300, 1341, 1383, 1412, 1451, 1665, 1703, 1826, 1846, 1957, 2023, 2054, 2117, 2262, 2539, 2563, 2729, 2756, 2759, 2803, 2826], 'T51B': [320, 1452], 'rat': [321, 696, 1342, 1453, 2425], 'liver': [322, 697, 1343, 1454, 2265, 2426], 'epithelial': [323, 698, 1344, 1455], 'cells': [324, 1346, 1456, 1532, 1705, 1961, 2144, 2305, 2427], 'expressing': [325, 1457], 'wild-type': [326], 'PDGF': [327, 336, 485, 1458, 2163], 'receptor': [328, 831, 2164], 'β': [329], '(PDGFrβ).': [330], 'Both': [331], 'these': [333, 375], 'actions': [334, 1894, 1903], 'required': [337, 2389], 'participation': [338, 550], 'C': [342, 1488], '(PKC)': [343], 'mitogen-activated': [345, 851, 1023, 1161, 1232, 1307, 1335, 1490, 1609, 2681, 2715, 2853], '(MAPK).': [348], 'Similar': [349], 'requirements': [350], 'MAPK': [352, 388, 402, 410, 438, 543], 'were': [353], 'suggested': [354], 'modulation': [357], 'other': [361, 505], 'agents,': [362], 'epidermal': [364, 1200, 1734], '(EGF)': [367], 'lysophosphatidic': [369], 'acid': [370, 1290, 1340], '(LPA).': [371], 'Since': [372], 'many': [373], 'agents': [376, 1261], 'activate': [377, 2258], 'additional': [378, 428, 552], 'kinases,': [380], 'present': [382], 'study': [383], 'examined': [384], 'whether': [385], 'activation': [386, 408, 1875, 2782], 'was': [389], 'blockade.': [396], 'By': [397], 'utilizing': [398], 'variety': [400], 'activators,': [403], 'we': [404], 'now': [405], 'show': [406], 'that': [407, 532, 1205, 1387, 1561], 'always': [413], 'associated': [414], 'either': [416, 541], 'or': [419, 446, 520, 544], 'GJC,': [422], 'which': [423], 'suggests': [424], 'requirement': [426], 'factors.': [429], 'Furthermore,': [430], 'pretreatment': [431, 456], 'hydrogen': [433, 2753], 'peroxide': [434, 2558, 2754], '(H2O2),': [435], 'potent': [437], 'activator': [439], 'but': [440, 476, 547, 2566], 'inefficient': [441], 'GJC/Cx43': [442], 'modulator,': [443], 'abrogated': [444], 'PDGF-': [445, 459], 'TPA-induced': [447, 461], 'GJC.': [450, 571], 'While': [451], '5': [453], 'min': [454], 'H2O2': [455, 469, 1262, 2360], 'abolished': [457], 'both': [458], 'blockade,': [466], 'simultaneous': [468], 'treatment': [470], 'interfered': [471], 'only': [472, 1411], 'closure': [475], 'induced': [483, 684, 2145], 'TPA.': [487], 'This': [488, 557], 'finding': [489], 'indicates': [490], 'that,': [491], 'addition': [493], 'step,': [498], 'inhibition': [499, 1103, 2170, 2393], 'requires': [502, 548, 2495], 'interaction': [503, 2848], 'components.': [506, 556], 'H2O2-mediated': [507], 'abrogation': [508], 'PDGF/TPA': [510], 'signaling': [511, 787, 1204, 1983], 'can': [512], 'neutralized': [514], 'antioxidant': [517], 'N-acetylcysteine': [518], '(NAC)': [519], 'tyrosine': [523, 1267, 1797, 2165], 'inhibitor': [525, 1020], 'genistein.': [526, 2762], 'Taken': [527], 'together,': [528], 'results': [530], 'suggest': [531], 'solely': [538], 'mediated': [539, 1636], 'activated': [542, 1796], 'kinases': [553, 607, 2261, 2620], 'regulatory': [555], 'complex': [558, 781], 'mode': [559], 'regulation': [561, 987, 1049, 1728, 2005], 'perhaps': [563], 'essential': [564], 'proposed': [567], 'functional': [568, 1935, 2027], 'role': [569, 1419, 2208], 'J.': [572], 'Cell.': [573], 'Physiol.': [574], '179:87–96,': [575], '1999.': [576], '©': [577], 'Wiley-Liss,': [579], 'Inc.': [580], 'LITERATURE': [581], 'CITED': [582], 'Aikawa': [583], 'R,': [584, 718, 796, 992, 1255, 1858, 2087, 2226, 2745], 'Komuro': [585], 'I,': [586, 596, 1253], 'Yamazaki': [587], 'T,': [588, 1720, 2129, 2184, 2282, 2288, 2517, 2523, 2614], 'Zou': [589], 'Y,': [590, 598, 1222, 1504, 1860, 2015, 2286, 2290, 2635, 2840], 'Kudoh': [591], 'S,': [592, 636, 1364, 1623, 1752, 2280, 2474], 'Tanaka': [593], 'M,': [594, 743, 845, 970, 1182, 1224, 1654, 1917, 2218, 2274, 2292, 2346, 2412, 2519, 2525, 2584], 'Shiojima': [595], 'Hiroi': [597], 'Yazaki': [599], 'Y.': [600, 1257, 2075, 2294], '1997.': [601, 801, 848, 1096, 1185, 1628, 1978, 2255, 2295, 2447, 2556], 'Oxidative': [602], 'stress': [603], 'activates': [604, 1509], 'extracellular': [605, 857, 2259], 'signal-regulated': [606, 2260], 'through': [608], 'src': [609], 'ras': [611, 659], 'cultured': [613], 'cardiac': [614, 2540], 'myocytes': [615], 'neonatal': [617], 'rats.': [618], 'J': [619, 702, 735, 789, 833, 867, 964, 1059, 1084, 1113, 1173, 1244, 1272, 1312, 1353, 1460, 1493, 1517, 1643, 1668, 1711, 1739, 1800, 1832, 1908, 2010, 2032, 2060, 2150, 2175, 2211, 2267, 2316, 2542, 2658, 2692, 2718, 2856], 'Clin': [620], 'Invest': [621], '100:': [622], '1813–1821.': [623], 'Medline': [624, 666, 739, 764, 794, 824, 872, 903, 936, 968, 1034, 1062, 1089, 1118, 1144, 1178, 1218, 1249, 1277, 1315, 1358, 1395, 1429, 1465, 1498, 1522, 1549, 1617, 1648, 1673, 1687, 1716, 1744, 1775, 1805, 1837, 1856, 1885, 1913, 1946, 1969, 1993, 2013, 2036, 2065, 2125, 2155, 2180, 2216, 2250, 2272, 2322, 2344, 2370, 2400, 2440, 2468, 2547, 2574, 2608, 2633, 2697, 2723, 2737, 2793, 2809, 2838, 2861], 'Arvidsson': [625], 'A-K,': [626], 'Rupp': [627], 'E,': [628, 630, 2470], 'Nanberg': [629], 'Downward': [631], 'J,': [632, 638, 841, 1093, 2186, 2326, 2476, 2580, 2769], 'Ronnstrand': [633], 'L,': [634, 1010, 2069, 2127, 2741], 'Wennstron': [635], 'Schlessinger': [637], 'Heldin': [639], 'CH,': [640], 'Claesson-Welsh': [641, 825], '1994.': [643, 1288, 1400, 1951, 2160, 2617, 2632], 'Tyr-716': [644], 'β-receptor': [650], 'insert': [652], 'involved': [654, 1198], 'GRB2': [656], 'binding': [657], 'activation.': [660, 1212, 1738], 'Mol': [661, 898, 1213, 1612, 1770, 1941, 2246, 2603], 'Cell': [662, 703, 899, 1174, 1214, 1424, 1461, 1494, 1518, 1614, 1684, 1712, 1772, 1833, 1852, 1909, 1943, 1989, 2061, 2176, 2212, 2340, 2396, 2604, 2628, 2733], 'Biol': [663, 704, 790, 834, 868, 900, 1085, 1115, 1141, 1175, 1215, 1245, 1273, 1354, 1519, 1613, 1644, 1669, 1740, 1771, 1834, 1853, 1910, 1942, 1990, 2062, 2151, 2213, 2268, 2465, 2543, 2605, 2629, 2659, 2693, 2719, 2734, 2857], '14:': [664], '6715–6726.': [665], 'Berthoud': [667], 'VM,': [668], 'Rook': [669], 'MB,': [670], 'Traub': [671], 'O,': [672, 1973], 'Hertzberg': [673], 'EL,': [674], 'Saez': [675], 'JC.': [676], '1993.': [677, 709, 1157, 1584, 2748], 'On': [678], 'mechanisms': [680, 2079], 'cell': [682, 699, 1166, 1239, 1405, 1830, 2058, 2601], 'uncoupling': [683, 757], 'promoter': [688], 'phorbol': [689, 2313], 'ester': [690, 2110, 2314], 'clone': [692], '9': [693], 'cells,': [694], 'line.': [700], 'Eur': [701, 734, 2031], '61:': [705], '384–396.': [706], 'Beyer': [707, 875], 'EC.': [708], 'Gap': [710, 999, 1572, 2019, 2094, 2508, 2727], 'junctions.': [711], 'Int': [712, 963], 'Rev': [713, 2627], 'Cytol': [714], '137C:': [715], '1–37.': [716], 'Bruzzone': [717], 'White': [719], 'TW,': [720], 'Paul': [721, 877, 1810, 2377], 'DL.': [722, 2378], '1996.': [723, 773, 1047, 1229, 1507, 1527, 1657, 1678, 1790, 2000, 2018, 2677, 2774, 2798, 2845], 'Connection': [724], 'connexins:': [726], 'molecular': [728, 1052, 2078], 'basis': [729], 'direct': [731], 'intercellular': [732, 807, 926, 954, 1105, 1955, 2300, 2712], 'signalling.': [733], 'Biochem': [736, 1311], '238:': [737], '1–27.': [738], 'Callero': [740], 'G,': [741, 911, 1038], 'Kanemitsu': [742, 1580, 1618, 1747, 2669], 'Taffet': [744, 977, 1043, 1996, 2473], 'SM,': [745, 1044, 1997], 'Lau': [746, 881, 1552, 1582, 1624, 1694, 1745, 1776, 2481, 2675, 2704], 'AF,': [747, 1625, 1746, 1777], 'Delmar': [748, 969, 1045, 1998], 'M.': [749, 1046, 1184, 1999, 2527], '1998.': [750, 979, 1067, 1123, 1554, 1696, 1869, 2076, 2195, 2485, 2528, 2706], 'A': [751, 980, 1018], '17mer': [752], 'peptide': [753], 'interferes': [754], 'acidification-induced': [756], 'connexin43.': [759, 989, 1565, 2657], 'Circ': [760], 'Res': [761, 2319, 2341], '82:': [762], '929–935.': [763], 'Chen': [765, 2074], 'D,': [766, 1251, 1811], 'Waters': [767], 'SB,': [768], 'Holt': [769], 'KH,': [770], 'Pessin': [771], 'JE.': [772, 2555], 'SOS': [774], 'disassociation': [777], 'Grb2-SOS': [780], 'ERK': [784], 'JNK': [786], 'pathway.': [788], 'Chem': [791, 835, 869, 1086, 1246, 1274, 1355, 1645, 1670, 1741, 2152, 2269, 2544, 2660, 2694, 2720, 2858], '271:': [792, 1247, 1671, 2661, 2695, 2859], '6328–6332.': [793], 'Choudhry': [795], 'Pitts': [797], 'JD,': [798], 'Hodgins': [799], 'MB.': [800], 'Changing': [802], 'patterns': [803], 'connexin': [810, 2801], 'distribution': [811], 'mouse': [813, 2264], 'epidermis': [814], 'hair': [816], 'follicle': [817], 'during': [818], 'development.': [819], 'Dev': [820, 2464], 'Dyn': [821], '210:': [822], '417–430.': [823], '1995.': [827, 1017, 1725, 2134, 2355, 2589, 2640], 'Platelet-derived': [828, 1473], 'signals.': [832], '269:': [836], '32023–32026.': [837], 'Cook': [838], 'SJ,': [839, 1012, 2131], 'Beltman': [840], 'Cadwallader': [842], 'KA,': [843], 'McMahon': [844, 1653], 'McCormick': [846], 'F.': [847], 'Regulation': [849, 1791, 2418, 2707, 2846], 'phosphatase-1': [854], 'expression': [855, 1410, 1932], 'signal-related': [858], 'kinase-dependent': [859], 'Ca2+-dependent': [861], 'signal': [862, 1081, 2365, 2623], 'pathways': [863], 'Rat-1': [865], 'cells.': [866, 932, 1112, 1271, 2119, 2266, 2338, 2570], '272:': [870, 1646, 2270], '13309–13319.': [871], 'Crow': [873], 'DS,': [874, 1152], 'EC,': [876], 'DL,': [878, 1150], 'Kobe': [879], 'SS,': [880], 'AF.': [882, 1553, 1583, 1695, 2676, 2705], '1990.': [883, 1258, 2045, 2231, 2379], 'Phosphorylation': [884], 'junction': [888, 1100, 1126, 1681, 2051, 2385, 2488, 2534, 2690], 'uninfected': [891], 'Rous': [893], 'sarcoma': [894], 'virus–transformed': [895], 'mammlian': [896], 'fibroblasts.': [897], '10:': [901, 2630], '1754–1763.': [902], 'Cruciani': [904, 937], 'V,': [905, 938], 'Rast': [906], 'C,': [907, 1551, 1809, 1862, 2842], 'Durand': [908], 'M-J,': [909], 'Nguyen-Ba': [910], 'Vasseur': [912, 941], 'P.': [913], '1997a.': [914], 'Comparative': [915], 'effects': [916, 2450], 'clofibrate': [918], 'methyl': [920], 'clofenapate': [921], 'on': [922, 953, 1768, 1897, 1904, 2453, 2686], 'morphological': [923], 'transformation': [924], 'Syrian': [929, 1958], 'hamster': [930, 960, 1959], 'embryo': [931, 1960], 'Carcinogenesis': [933, 1392, 1546, 1966, 2571, 2806, 2835], '18:': [934, 2572], '701–706.': [935], 'Mikalsen': [939, 1947], 'SO,': [940], 'P,': [942, 1433, 1469, 2472, 2612], 'Sanner': [943, 1949], 'T.': [944, 1950, 2354], '1997b.': [945], 'Effects': [946], 'peroxisome': [948], 'proliferators': [949, 2257], '12-O-tetradecanoyl': [951], 'phorbol-13-acetate': [952], 'two': [959], 'fibroblast': [961, 2308], 'systems.': [962], 'Cancer': [965, 2765], '73:': [966], '240–248.': [967], 'Stergiopoulos': [971], 'K,': [972, 1813, 2192, 2278, 2284, 2352, 2478, 2521, 2743], 'Homma': [973], 'N,': [974, 1180], 'Ek-Vitorin': [975, 1035], 'JF,': [976, 1036, 2404], 'SM.': [978], 'ball-and': [981], 'chain': [982], 'model': [983], 'chemical': [986], 'In:': [990, 1566, 2085, 2499], 'Werner': [991, 2086], 'editor.': [993, 2088, 2502], 'Proceedings': [994, 1567, 2089, 2503], '1997': [997, 1570, 2092, 2506], 'International': [998, 1571, 2093, 2507], 'Junctional': [1000, 1573, 2095, 2509], 'Conference.': [1001, 1574, 2096, 2510], 'Amsterdam:': [1002, 1575, 2097, 2511], 'IOS': [1003, 1576, 2098, 2512], 'Press.': [1004, 1577, 2099, 2513], 'p': [1005, 1578, 2100, 2514], '8–12.': [1006], 'Dudley': [1007], 'DT,': [1008], 'Pang': [1009, 2126], 'Decker': [1011, 2130], 'Bridges': [1013], 'AJ,': [1014], 'Saltiel': [1015, 1721, 2132], 'AR.': [1016, 2133], 'synthetic': [1019], 'cascade.': [1026, 1310], 'Proc': [1027], 'Natl': [1028], 'Acad': [1029, 2436], 'Sci': [1030, 1713, 2437], 'USA': [1031], '92:': [1032], '7686–7689.': [1033], 'Calero': [1037], 'Morley': [1039], 'GE,': [1040, 1995], 'Coombs': [1041], 'W,': [1042, 1787, 2480, 2674], 'pH': [1048, 2004], 'connexin43:': [1051], 'analysis': [1053], 'gating': [1056], 'particle.': [1057], 'Biophys': [1058, 2009, 2121], '71:': [1060], '1273–1284.': [1061], 'Falk': [1063], 'MM,': [1064], 'Gilula': [1065, 1676], 'NB.': [1066, 1677], 'Connexin': [1068], 'membrane': [1069, 1169], 'biosynthesis': [1071], 'influenced': [1073], 'polypeptide': [1075], 'positioning': [1076], 'within': [1077], 'translocon': [1079], 'peptidase': [1082], 'access.': [1083], '273:': [1087, 2545, 2721, 2791], '7856–7864.': [1088], 'Feldman': [1090], 'PA,': [1091], 'Kim': [1092], 'Laird': [1094], 'DW.': [1095], 'Loss': [1097], 'plaques': [1101], 'ilimaquinone-treated': [1108], 'BICR-M1Rk': [1109], 'NRK': [1111], 'Membr': [1114], '155:': [1116], '275–287.': [1117], 'Giepmans': [1119, 2187], 'BNG,': [1120, 2188], 'Moolenaar': [1121, 1970, 2193], 'WH.': [1122, 2194], 'The': [1124, 1259, 1528, 1679, 1843, 1893, 2448], 'interacts': [1129], 'second': [1132], 'PDZ': [1133], 'domain': [1134, 1641], 'zona': [1137], 'occludens-1': [1138], 'protein.': [1139, 2245, 2691], 'Curr': [1140, 1987], '8:': [1142], '931–934.': [1143], 'Gonzalez': [1145], 'FA,': [1146], 'Seth': [1147], 'A,': [1148, 1319, 1329, 1362, 1370, 2482, 2586], 'Raden': [1149], 'Bowman': [1151], 'Fay': [1153], 'FS,': [1154], 'Davis': [1155], 'RJ.': [1156], 'Serum-induced': [1158], 'translocation': [1159], 'surface': [1167], 'ruffling': [1168], 'nucleus.': [1172], '122:': [1176], '1089–1101.': [1177], 'Gotoh': [1179], 'Toyoda': [1181], 'Shibuya': [1183], 'Tyrosine': [1186, 1629, 2380], 'sites': [1188, 2685], 'at': [1189], 'amino': [1190], 'acids': [1191, 1382], '239': [1192], '240': [1194], 'shc': [1196], 'factor-induced': [1202], 'mitogenic': [1203], 'distinct': [1207, 1700], 'from': [1208, 2168], 'ras/mitogen-activated': [1209], '17:': [1216, 1547, 2807], '1824–1831.': [1217], 'Guyton': [1219], 'KZ,': [1220], 'Liu': [1221], 'Gorospe': [1223], 'Xu': [1225], 'Q,': [1226], 'Holbrook': [1227], 'NJ.': [1228], 'Activation': [1230, 1333], 'H2O2.': [1236], 'Role': [1237, 1658, 2799], 'survival': [1240], 'following': [1241, 2490], 'oxidant': [1242], 'injury.': [1243], '4138–4142.': [1248], 'Heffetz': [1250], 'Bushkin': [1252], 'Dror': [1254], 'Zick': [1256], 'insulinomimetic': [1260], 'vanadate': [1264], 'stimulate': [1265], 'phsophorylation': [1268], 'intact': [1270], '265:': [1275], '2896–2902.': [1276], 'Hii': [1278, 1316, 1359], 'CS,': [1279, 1317, 1360], 'Oh': [1280, 2102], 'SY,': [1281, 2103], 'Schmidt': [1282, 1363], 'SA,': [1283], 'Clark': [1284], 'KJ,': [1285], 'Murray': [1286, 1330, 1371, 2106], 'AW.': [1287, 1331, 1372, 2107], 'Lysophosphatidic': [1289, 1979], 'inhibits': [1291, 2559], 'stimulates': [1296, 1588], 'WB': [1301, 1345, 1384, 2118], 'cells:': [1302, 1385, 1415, 2828], 'possible': [1303, 1606], 'involvement': [1304, 1607], '303:': [1313], '475–479.': [1314], 'Ferrante': [1318, 1361], 'Edwards': [1320], 'YS,': [1321], 'Huang': [1322, 1499], 'ZH,': [1323], 'Hartfield': [1324], 'PJ,': [1325], 'Rathjen': [1326, 1365], 'DA,': [1327, 1366], 'Poulos': [1328, 1369], '1995a.': [1332], 'arachidonic': [1339], 'C–dependent': [1351], 'mechanism.': [1352], '270:': [1356, 1742, 2153, 2368], '4201–4204.': [1357], 'Robinson': [1367], 'BS,': [1368], '1995b.': [1373], 'Inhibition': [1374, 2135, 2641, 2749], 'polyunsaturated': [1380], 'fatty': [1381], 'evidence': [1386], 'hyperphosphorylated.': [1391], '16:': [1393], '1505–1511.': [1394], 'MZ,': [1397, 1431, 1467, 2222], 'Bertram': [1398, 1888, 2229, 2814], 'JS.': [1399, 2230, 2815], 'Retinoids': [1401], 'suppress': [1402], 'proliferation,': [1403], 'induce': [1404], 'spreading': [1406], 'up-regulate': [1408], 'post-confluent': [1413], '10T1/2': [1414], 'implications': [1416], 'communication.': [1423, 1545, 1907, 2174, 2395], 'Growth': [1425], 'Differ': [1426], '5:': [1427], '1253–1261.': [1428], 'AL.': [1435, 1471, 1754, 2159], '1998a.': [1436], 'Rapid': [1437], 'receptor.': [1459], 'Physiol': [1462, 1495, 2177], '174:': [1463], '66–77.': [1464], '1998b.': [1472], 'factor–induced': [1475], 'involves': [1485], 'kinase.': [1492, 1611, 1710, 2717, 2789, 2855], '176:': [1496], '332–341.': [1497], 'RP,': [1500], 'Wu': [1501], 'JX,': [1502], 'Fan': [1503], 'Adamson': [1505], 'ED.': [1506], 'UV': [1508], 'receptors': [1512], 'via': [1513], 'reactive': [1514], 'oxygen': [1515], 'intermediates.': [1516], '133:': [1520], '211–220.': [1521], 'Jansen': [1523], 'LAM,': [1524], 'Jongen': [1525], 'WMF.': [1526], 'use': [1529], 'initiated': [1531], 'as': [1533], 'test': [1535], 'system': [1536], 'detection': [1539], 'inhibitors': [1541], '333–339.': [1548], 'Jin': [1550], 'Characterization': [1555, 2678], 'novel': [1558], 'SH3-containing': [1559], 'may': [1562], 'interact': [1563], '230–234.': [1579], 'MY,': [1581, 1619, 1748, 1781, 2670], 'Epidermal': [1585, 1756], 'independent': [1598], '12-O-tetradecanoylphorbol': [1600], '13-acetate–sensitive': [1601], 'C:': [1604], '4:': [1615], '837–848.': [1616], 'Loo': [1620, 1782, 2671], 'LWM,': [1621, 1783, 2672], 'Simon': [1622], 'Eckhert': [1626], 'W.': [1627], 'v-src': [1634], 'SH2': [1638], 'SH3': [1640], 'interaction.': [1642], '22824–22831.': [1647], 'Klarlund': [1649], 'JK,': [1650], 'Cherniack': [1651], 'AD,': [1652], 'Czech': [1655], 'MP.': [1656], 'raf/mitogen-activated': [1661], 'pathway': [1664, 2779], 'p21ras': [1666, 1737], 'desensitization.': [1667], '16674–16677.': [1672], 'Kumar': [1674], 'NM,': [1675], 'channel.': [1683], '84:': [1685], '381–388.': [1686], 'Lampe': [1688, 1788, 2471, 2665], 'PD,': [1689, 2666], 'Kurata': [1690, 1749, 1778, 2479, 2667], 'WE,': [1691, 1750, 1779], 'Warn-Cramer': [1692, 1784, 2663, 2698], 'BJ,': [1693, 1785, 2067, 2228, 2664, 2699], 'Formation': [1697], 'phosphoisoform': [1702], 'mitotic': [1704, 2334], 'dependent': [1707], 'upon': [1708], 'p34cdc2': [1709], '111:': [1714, 2063], '833–841.': [1715], 'Langlois': [1717], 'WJ,': [1718], 'Sasaoka': [1719], 'AR,': [1722], 'Olefsky': [1723], 'JM.': [1724], 'Negative': [1726], 'feedback': [1727], 'desensitization': [1730], 'insulin-': [1732], 'factor–stimulated': [1736], '25320–25323.': [1743], 'Danesh': [1751], '1992.': [1755, 1816, 1842, 1920, 2329, 2726], 'disrupts': [1759], 'induces': [1764, 2111, 2644], 'serine.': [1769], '3:': [1773, 1854, 1944, 2248, 2735], '865–874.': [1774], 'Kanetmitsu': [1780], 'Eckhart': [1786, 2673], 'PD.': [1789], 'function': [1794], 'kinases.': [1799], 'Bioenerg': [1801], 'Biomembr': [1802], '28:': [1803], '359–368.': [1804], 'Lee': [1806], 'SW,': [1807], 'Tomasetto': [1808], 'Keyomarsi': [1812], 'Sager': [1814], 'R.': [1815, 2446, 2484], 'Transcriptional': [1817], 'downregulation': [1818], 'proteins': [1822], 'blocks': [1823, 2139], 'human': [1827], 'mammary': [1828], 'lines.': [1831, 2059], '118:': [1835], '1213–1221.': [1836], 'Loewenstein': [1838, 1890], 'WR,': [1839], 'Rose': [1840, 1918, 2638], 'cell-cell': [1844, 2199, 2331], 'channel': [1845, 2083], 'control': [1848], 'growth.': [1850], 'Semin': [1851, 2732], '59–79.': [1855], 'Marais': [1857], 'Light': [1859], 'Mason': [1861], 'Paterson': [1863], 'H,': [1864, 2073, 2276, 2374, 2376, 2739, 2795], 'Olson': [1865], 'MF,': [1866], 'Marshall': [1867], 'CJ.': [1868], 'Requirement': [1870, 2356], 'ras-GTP-raf': [1872], 'complexes': [1873], 'raf-1': [1877], 'C.': [1881], 'Science': [1882, 2367, 2790], '280:': [1883], '109–112.': [1884], 'Mehta': [1886, 1914, 2636], 'PP,': [1887, 1915, 2637], 'JS,': [1889], 'WR.': [1891], '1989.': [1892], 'retinoids': [1896], 'cellular': [1898, 1985], 'correlate': [1900], 'their': [1902, 2622, 2831], '108:': [1911], '1053–1065.': [1912], 'Yamamoto': [1916], 'Transcription': [1921], 'gene': [1924, 2781], 'channels': [1936, 2649], 'regulated': [1938], 'cAMP.': [1940], '839–850.': [1945], 'S-O,': [1948], 'Increased': [1952], 'treated': [1962], 'oxidative': [1964], 'agents.': [1965], '15:': [1967, 2606], '381–387.': [1968], 'WH,': [1971], 'Kranenburg': [1972], 'Postma': [1974, 2181], 'FR,': [1975, 2182], 'Zondag': [1976, 2189], 'GCM.': [1977], 'acid:': [1980], 'G': [1981, 2203], 'responses.': [1986], 'Opin': [1988], '9:': [1991], '168–173.': [1992], 'Morely': [1994], 'Intramolecular': [2001], 'interactions': [2002], 'mediate': [2003], 'channels.': [2008], '70:': [2011], '1294–1302.': [2012], 'Munari-Silem': [2014], 'Rousset': [2016], 'junction–mediated': [2020], 'cell-to-cell': [2021, 2648], 'endocrine': [2024], 'glands—molecular': [2025], 'aspects:': [2028], 'review.': [2030], 'Endocrinol': [2033], '135:': [2034], '251–264.': [2035], 'Musil': [2037], 'LS,': [2038, 2324], 'Cunningham': [2039], 'BA,': [2040], 'Edelman': [2041], 'GA,': [2042], 'Goodenough': [2043], 'DA.': [2044], 'Differential': [2046], 'connexin-43': [2053, 2688, 2709], 'communication-competent': [2055], '-deficient': [2057], '2077–2088.': [2064], 'Nicholson': [2066, 2227], 'Zhou': [2068], 'Cao': [2070], 'F,': [2071], 'Zhu': [2072], 'Diverse': [2077], 'gating.': [2084], '3–7.': [2101], 'Grupen': [2104], 'GS,': [2105], '1991.': [2108, 2816], 'Phorbol': [2109], 'down-regulation': [2114], 'Biochim': [2120], 'Acta': [2122], '1094:': [2123], '243–248.': [2124], 'Sawada': [2128], 'MAP': [2137], 'differentiation': [2141], 'PC-12': [2143], 'nerve': [2147], 'factor.': [2149], '13585–13588.': [2154], 'Pelletier': [2156], 'DB,': [2157], 'Dissociation': [2161], 'activity': [2167], 'PDGF-mediated': [2169], '158:': [2178], '427–434.': [2179], 'Hengeveld': [2183], 'Alblas': [2185], 'GCM,': [2190], 'Jalnik': [2191], 'Acute': [2196], 'loss': [2197], 'caused': [2201], 'protein–coupled': [2204], 'receptors:': [2205], 'critical': [2207], 'c-src.': [2210], '140:': [2214], '1199–1209.': [2215], 'Rogers': [2217], 'Berestecky': [2219], 'JM,': [2220, 2703], 'Guo': [2223], 'HM,': [2224], 'Kadle': [2225], 'Retinoid-enhanced': [2232], 'achieved': [2237], 'increased': [2239], 'levels': [2240], 'mRNA': [2243], 'Carcinog': [2247], '335–343.': [2249], 'Rokos': [2251], 'CL,': [2252], 'Ledwith': [2253], 'BJ.': [2254], 'Peroxisome': [2256], 'immortalized': [2263], '13452–13457.': [2271], 'Shiokawa-Sawada': [2273], 'Mano': [2275], 'Hanada': [2277], 'Kakudo': [2279], 'Kameda': [2281], 'Miyazawa': [2283], 'Nakamaru': [2285], 'Yuasa': [2287], 'Mori': [2289], 'Kumegawa': [2291], 'Hakeda': [2293], 'Down-regulation': [2296], 'between': [2302, 2333], 'osteoblastic': [2303], 'MC3T3-E1': [2304], 'basic': [2307], '(12-O-tetradecanoylphorbol-13-acetate).': [2315], 'Bone': [2317], 'Miner': [2318], '12:': [2320, 2836], '1165–1173.': [2321], 'Stein': [2323], 'Boonstra': [2325], 'Burghardt': [2327], 'RC.': [2328], 'Reduced': [2330], 'non-mitotic': [2336], 'coupled': [2337], 'Exp': [2339], '198:': [2342], '1–7.': [2343], 'Sundaresan': [2345], 'Yu': [2347], 'Z-X,': [2348], 'Ferrans': [2349], 'VJ,': [2350], 'Irani': [2351], 'Finkel': [2353], 'generation': [2358], 'transduction.': [2366], '296–299.': [2369], 'Swenson': [2371], 'KI,': [2372], 'Piwnica-Worms': [2373], 'McNamee': [2375], 'pp60v-src–induced': [2392], 'Regul': [2397], '1:': [2398], '989–1002.': [2399], 'Swierenga': [2401], 'SHH,': [2402], 'Whitfield': [2403], 'AL,': [2406], 'MacManus': [2407], 'JP,': [2408], 'Rixon': [2409], 'RH,': [2410], 'Sikorska': [2411], 'Tsang': [2413], 'BK,': [2414], 'Walker': [2415], 'PR.': [2416], '1980.': [2417], 'proliferation': [2420], 'normal': [2422], 'neoplastic': [2424], 'calcium': [2429], 'cyclic': [2431], 'AMP.': [2432], 'Ann': [2433], 'N': [2434], 'Y': [2435], '349:': [2438], '294–311.': [2439], 'TenBroek': [2441, 2469], 'EM,': [2442], 'Louis': [2443], 'CF,': [2444], 'Johnson': [2445, 2483, 2587], 'differential': [2449], '12-O-tetradecanoylphorbol-13-acetate': [2452], 'junctions': [2456, 2728], 'connexins': [2458], 'developing': [2461], 'mammalian': [2462], 'lens.': [2463], '191:': [2466], '88–102.': [2467], 'Reynhout': [2475], 'Martyn': [2477], 'Enhanced': [2486], 'assembly': [2489], 'elevation': [2492], 'cAMP': [2494], 'length': [2497], 'Cx43.': [2498], 'R': [2500], 'Werner,': [2501], '215–219.': [2515], 'Toyofuku': [2516], 'Yabuki': [2518], 'Otsu': [2520], 'Kuzuya': [2522], 'Hori': [2524], 'Tada': [2526], 'Direct': [2529], 'association': [2530], 'ZO-1': [2538], 'myocytes.': [2541], '12725–12731.': [2546], 'Upham': [2548], 'BL,': [2549], 'Kang': [2550], 'K-S,': [2551], 'Cho': [2552], 'H-Y,': [2553], 'Trosko': [2554], 'Hydrogen': [2557], 'glutathione': [2564, 2568], 'deficient': [2569], '37–42.': [2573], 'Vaillancourt': [2575], 'RV,': [2576, 2813], 'Heasley': [2577], 'LE,': [2578], 'Zamarripa': [2579], 'Storey': [2581], 'B,': [2582], 'Valius': [2583], 'Kazlauskas': [2585], 'GL.': [2588], 'insufficient': [2594], 'receptor–mediated': [2599], 'PC12': [2600], 'differentiation.': [2602], '3644–3653.': [2607], 'van': [2609], 'der': [2610], 'Geer': [2611], 'Hunter': [2613], 'Lindberg': [2615], 'RA.': [2616], 'Receptor': [2618], 'protein-tyrosine': [2619], 'transduction': [2624], 'pathways.': [2625], 'Annu': [2626], '251–337,': [2631], 'Wang': [2634], 'glycosylation': [2643], 'formation': [2645, 2755], 'open-connexin43': [2647], 'Triton': [2653], 'X-100': [2654], 'insolubility': [2655], '3779–3786.': [2662, 2696], 'WF,': [2668], 'Cottrell': [2700], 'GT,': [2701], 'Burt': [2702], '9188–9196.': [2722], 'Warner': [2724], 'AE.': [2725], 'development—a': [2730], 'perspective.': [2731], '81–91.': [2736], 'Wei': [2738, 2740], 'Frenkel': [2742], 'Bowen': [2744], 'Barnes': [2746], 'S.': [2747], 'promoter–induced': [2752], 'vitro': [2757], 'vivo': [2760], 'S': [2763], 'Nutr': [2764], '20:': [2766], '1–12.': [2767], 'Xing': [2768], 'Ginty': [2770], 'DD,': [2771], 'Greenberg': [2772], 'ME.': [2773], 'Coupling': [2775], 'RAS-MAPK': [2778], 'RSK2,': [2784], 'factor-regulated': [2787], 'CREB': [2788], '959–963.': [2792], 'Yamasaki': [2794], 'Naus': [2796], 'CCG.': [2797], 'genes': [2802], 'control.': [2805], '1199–1213.': [2808], 'Zhang': [2810], 'L-X,': [2811], 'Cooney': [2812], 'Carotenoids': [2817], 'enhance': [2818], 'inhibit': [2823], 'lipid': [2824], 'peroxidation': [2825], 'C3H/10T1/2': [2827], 'relationship': [2829], 'cancer': [2832], 'chemopreventive': [2833], 'action.': [2834], '2109–2114.': [2837], 'Zhao': [2839], 'Bjorbaek': [2841], 'Moller': [2843], 'DE.': [2844], 'pp90rsk': [2850], 'isoforms': [2851], '29773–29779.': [2860], 'Citing': [2862], 'Literature': [2863], 'Volume179,': [2864], 'Issue1April': [2865], '1999Pages': [2866], 'ReferencesRelatedInformation': [2868]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2063379016', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-16T13:02:00.275487', 'created_date': '2016-06-24'}