<i>N-tert</i>-Butoxycarbonyl (BOC) Deprotection Using Boron Trifluoride Etherate

Name: Work Video:
Duration: 3 min 30 s
Description: Abstract A mild and efficient procedure is described for the removal of the tert-butoxycarbonyl (BOC) group using boron trifluoride etherate and molecular sieves in dichloromethane at room temperature. The scope of this procedure is explored for the deprotection of a variety of amines including amino acid derivatives.
Emily F. Evans; Norman Lewis; Isabelle Kapfer; Gregor J. Macdonald; Richard J. K. Taylor
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