Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2061533356', 'doi': 'https://doi.org/10.1016/j.febslet.2007.09.015', 'title': 'The two divergent PEP‐carboxylase catalytic subunits in the green microalga <i>Chlamydomonas reinhardtii</i> respond reversibly to inorganic‐N supply and co‐exist in the high‐molecular‐mass, hetero‐oligomeric Class‐2 PEPC complex', 'display_name': 'The two divergent PEP‐carboxylase catalytic subunits in the green microalga <i>Chlamydomonas reinhardtii</i> respond reversibly to inorganic‐N supply and co‐exist in the high‐molecular‐mass, hetero‐oligomeric Class‐2 PEPC complex', 'publication_year': 2007, 'publication_date': '2007-09-17', 'ids': {'openalex': 'https://openalex.org/W2061533356', 'doi': 'https://doi.org/10.1016/j.febslet.2007.09.015', 'mag': '2061533356', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17888908'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.febslet.2007.09.015', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2007.09.015', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2007.09.015', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5026615757', 'display_name': 'Eric R. Moellering', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114395901', 'display_name': 'University of Nebraska–Lincoln', 'ror': 'https://ror.org/043mer456', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114395901']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eric R. Moellering', 'raw_affiliation_strings': ['Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA', 'institution_ids': ['https://openalex.org/I114395901']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057193364', 'display_name': 'Yexin Ouyang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114395901', 'display_name': 'University of Nebraska–Lincoln', 'ror': 'https://ror.org/043mer456', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114395901']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yexin Ouyang', 'raw_affiliation_strings': ['Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA', 'institution_ids': ['https://openalex.org/I114395901']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109164328', 'display_name': 'Tarlan Mamedov', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114395901', 'display_name': 'University of Nebraska–Lincoln', 'ror': 'https://ror.org/043mer456', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114395901']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tarlan G. Mamedov', 'raw_affiliation_strings': ['Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA', 'institution_ids': ['https://openalex.org/I114395901']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5070949945', 'display_name': 'Raymond Chollet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114395901', 'display_name': 'University of Nebraska–Lincoln', 'ror': 'https://ror.org/043mer456', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I114395901']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Raymond Chollet', 'raw_affiliation_strings': ['Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA', 'Plant Science Initiative, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0660, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0664, USA', 'institution_ids': ['https://openalex.org/I114395901']}, {'raw_affiliation_string': 'Plant Science Initiative, University of Nebraska-Lincoln, George W. Beadle Center, Lincoln, NE 68588-0660, USA', 'institution_ids': ['https://openalex.org/I114395901']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5070949945'], 'corresponding_institution_ids': ['https://openalex.org/I114395901'], 'apc_list': {'value': 3610, 'currency': 'USD', 'value_usd': 3610, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.793, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.701426, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '581', 'issue': '25', 'first_page': '4871', 'last_page': '4876'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10303', 'display_name': 'Photosynthetic Processes and Mechanisms', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11162', 'display_name': 'Enzyme Structure and Function', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chlamydomonas-reinhardtii', 'display_name': 'Chlamydomonas reinhardtii', 'score': 0.9463198}, {'id': 'https://openalex.org/keywords/phosphoenolpyruvate-carboxylase', 'display_name': 'Phosphoenolpyruvate carboxylase', 'score': 0.91457886}, {'id': 'https://openalex.org/keywords/homotetramer', 'display_name': 'Homotetramer', 'score': 0.8883134}, {'id': 'https://openalex.org/keywords/molecular-mass', 'display_name': 'Molecular mass', 'score': 0.5312564}, {'id': 'https://openalex.org/keywords/chlamydomonas', 'display_name': 'Chlamydomonas', 'score': 0.42132488}], 'concepts': [{'id': 'https://openalex.org/C2777727519', 'wikidata': 'https://www.wikidata.org/wiki/Q291827', 'display_name': 'Chlamydomonas reinhardtii', 'level': 4, 'score': 0.9463198}, {'id': 'https://openalex.org/C111341932', 'wikidata': 'https://www.wikidata.org/wiki/Q908180', 'display_name': 'Phosphoenolpyruvate carboxylase', 'level': 3, 'score': 0.91457886}, {'id': 'https://openalex.org/C2778481663', 'wikidata': 'https://www.wikidata.org/wiki/Q3408232', 'display_name': 'Homotetramer', 'level': 4, 'score': 0.8883134}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.60320574}, {'id': 'https://openalex.org/C140137476', 'wikidata': 'https://www.wikidata.org/wiki/Q21114968', 'display_name': 'Pyruvate carboxylase', 'level': 3, 'score': 0.55430675}, {'id': 'https://openalex.org/C58121356', 'wikidata': 'https://www.wikidata.org/wiki/Q182854', 'display_name': 'Molecular mass', 'level': 3, 'score': 0.5312564}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5113382}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.5074379}, {'id': 'https://openalex.org/C104292427', 'wikidata': 'https://www.wikidata.org/wiki/Q899781', 'display_name': 'Protein subunit', 'level': 3, 'score': 0.49797893}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.49064007}, {'id': 'https://openalex.org/C50212798', 'wikidata': 'https://www.wikidata.org/wiki/Q422516', 'display_name': 'RuBisCO', 'level': 3, 'score': 0.48276392}, {'id': 'https://openalex.org/C2776580309', 'wikidata': 'https://www.wikidata.org/wiki/Q133008', 'display_name': 'Chlamydomonas', 'level': 4, 'score': 0.42132488}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.35874876}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D020418', 'descriptor_name': 'Algal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016825', 'descriptor_name': 'Chlamydomonas reinhardtii', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D010730', 'descriptor_name': 'Phosphoenolpyruvate Carboxylase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020418', 'descriptor_name': 'Algal Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D020418', 'descriptor_name': 'Algal Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D020418', 'descriptor_name': 'Algal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000918', 'descriptor_name': 'Antibody Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020134', 'descriptor_name': 'Catalytic Domain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016825', 'descriptor_name': 'Chlamydomonas reinhardtii', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003470', 'descriptor_name': 'Culture Media', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015180', 'descriptor_name': 'Electrophoresis, Gel, Two-Dimensional', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004591', 'descriptor_name': 'Electrophoresis, Polyacrylamide Gel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015151', 'descriptor_name': 'Immunoblotting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010730', 'descriptor_name': 'Phosphoenolpyruvate Carboxylase', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D010730', 'descriptor_name': 'Phosphoenolpyruvate Carboxylase', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D010730', 'descriptor_name': 'Phosphoenolpyruvate Carboxylase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011489', 'descriptor_name': 'Protein Denaturation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021122', 'descriptor_name': 'Protein Subunits', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D021122', 'descriptor_name': 'Protein Subunits', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D021122', 'descriptor_name': 'Protein Subunits', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D021122', 'descriptor_name': 'Protein Subunits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000644', 'descriptor_name': 'Quaternary Ammonium Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000644', 'descriptor_name': 'Quaternary Ammonium Compounds', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003313', 'descriptor_name': 'Zea mays', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D003313', 'descriptor_name': 'Zea mays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.febslet.2007.09.015', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2007.09.015', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17888908', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.febslet.2007.09.015', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.febslet.2007.09.015', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/15', 'display_name': 'Life on land', 'score': 0.52}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 22, 'referenced_works': ['https://openalex.org/W1963530308', 'https://openalex.org/W1985019648', 'https://openalex.org/W2003357793', 'https://openalex.org/W2005065858', 'https://openalex.org/W2010971306', 'https://openalex.org/W2030698162', 'https://openalex.org/W2054173524', 'https://openalex.org/W2059781914', 'https://openalex.org/W2063331014', 'https://openalex.org/W2087812644', 'https://openalex.org/W2099977944', 'https://openalex.org/W2108900585', 'https://openalex.org/W2118008650', 'https://openalex.org/W2119133512', 'https://openalex.org/W2132734243', 'https://openalex.org/W2136296341', 'https://openalex.org/W2138154963', 'https://openalex.org/W2142094348', 'https://openalex.org/W2145013322', 'https://openalex.org/W2145253477', 'https://openalex.org/W2156632286', 'https://openalex.org/W2161070187'], 'related_works': ['https://openalex.org/W982160137', 'https://openalex.org/W4385658311', 'https://openalex.org/W4245886947', 'https://openalex.org/W3092054307', 'https://openalex.org/W2529233322', 'https://openalex.org/W230946013', 'https://openalex.org/W2144145338', 'https://openalex.org/W2058875539', 'https://openalex.org/W2041808497', 'https://openalex.org/W1964404589'], 'abstract_inverted_index': {'Our': [0], 'recent': [1], 'molecular': [2, 61], 'studies': [3], 'revealed': [4], 'two': [5, 51, 85], 'divergent': [6], 'PEP‐carboxylase': [7], '(PEPC': [8], '[Ppc])': [9], 'encoding': [10, 57], 'genes': [11, 56], 'in': [12, 29, 67, 89], 'the': [13, 35, 68, 81, 90, 98, 133, 148], 'green': [14, 69], 'microalga': [15, 70], 'Chlamydomonas': [16], 'reinhardtii': [17, 72], ',': [18, 22, 73], 'CrPpc1': [19, 110], 'and': [20, 31, 42, 47, 54, 59, 93, 112], 'CrPpc2': [21, 113], 'which': [23, 101], 'are': [24], 'coordinately': [25], 'responsive': [26], 'to': [27, 147], 'changes': [28], 'inorganic‐N': [30], '‐C': [32], 'supply': [33], 'at': [34], 'transcript': [36], 'level': [37], '[Mamedov,': [38], 'T.G.,': [39], 'Moellering,': [40], 'E.R.': [41], 'Chollet,': [43], 'R.': [44], '(2005)': [45], 'Identification': [46], 'expression': [48], 'analysis': [49], 'of': [50, 63, 83, 100, 127, 135, 145], 'inorganic': [52], 'C‐': [53], 'N‐responsive': [55], 'novel': [58, 104], 'distinct': [60], 'forms': [62], 'eukaryotic': [64], 'phosphoenolpyruvate': [65], 'carboxylase': [66], 'C.': [71], 'Plant': [74], 'J.': [75], '42,': [76], '832–843].': [77], 'Here,': [78], 'we': [79], 'report': [80], 'distribution': [82], 'these': [84], 'encoded': [86], 'catalytic': [87, 138], 'subunits': [88, 139], 'minor': [91], 'Class‐1': [92, 117], 'predominant': [94], 'Class‐2': [95], 'PEPC': [96, 123], 'enzyme‐forms,': [97], 'latter': [99], 'is': [102, 120, 140], 'a': [103, 121], 'high‐molecular‐mass,': [105], 'hetero‐oligomeric': [106], 'complex': [107], 'containing': [108], 'both': [109, 136], '(p109)': [111], '(p131)': [114], 'polypeptides.': [115], 'The': [116], 'enzyme,': [118], 'however,': [119], 'typical': [122], 'homotetramer': [124], 'comprised': [125], 'solely': [126], 'p109.': [128], 'We': [129], 'also': [130], 'document': [131], 'that': [132], 'amount': [134], 'CrPpc1/2': [137], 'up‐/down‐regulated': [141], 'by': [142], 'varying': [143], 'levels': [144], 'supplied': [146], 'culture': [149], 'medium.': [150]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2061533356', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-09T04:43:43.487274', 'created_date': '2016-06-24'}