Title: Inhibitory Effects of Onion Against α-Glucosidase Activity and its Correlation with Phenolic Antioxidants
Abstract: Onion is used for treating diabetes in Chinese civil practices; however, the anti-diabetic mechanism was not clear. To investigate the potential mechanism of onion in diabetes treatment, total phenolic content, antioxidant activity, and α-glucosidase and α-amylase inhibitory activity were assessed. Both 70% ethanol extracts and boiling water extracts from white onion, red onion, and commercial dry onion powder, bitter melon, pumpkin, yam, and medlar exhibited inhibitory activities against α-glucosidase. Total phenolic content values of samples were positively related to α-glucosidase inhibitory activities (p < 0.05). Antioxidant analyses suggested that onions possessed strong free radical scavenging capacities. These results indicated that onions showed potential to be effective anti-diabetic agents.
Publication Year: 2013
Publication Date: 2013-11-08
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 41
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