Title: A Phase I Study of an Adeno-Associated Virus-CFTR Gene Vector in Adult CF Patients with Mild Lung Disease. Johns Hopkins Children's Center, Baltimore, Maryland
Abstract: Human Gene TherapyVol. 7, No. 9 Clinical ProtocolsA Phase I Study of an Adeno-Associated Virus-CFTR Gene Vector in Adult CF Patients with Mild Lung Disease. Johns Hopkins Children's Center, Baltimore, MarylandPRINCIPAL INVESTIGATOR Terence Flotte, CO-INVESTIGATORS Barrie Carter, Carol Conrad, William Guggino, Thomas Reynolds, Beryl Rosenstein, George Taylor, Sandra Walden, and Randall WetzelPRINCIPAL INVESTIGATOR Terence FlotteSearch for more papers by this author, CO-INVESTIGATORS Barrie CarterSearch for more papers by this author, Carol ConradSearch for more papers by this author, William GugginoSearch for more papers by this author, Thomas ReynoldsSearch for more papers by this author, Beryl RosensteinSearch for more papers by this author, George TaylorSearch for more papers by this author, Sandra WaldenSearch for more papers by this author, and Randall WetzelSearch for more papers by this authorPublished Online:20 Mar 2008https://doi.org/10.1089/hum.1996.7.9-1145AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetailsCited byImmunosuppression reduces rAAV2.5T neutralizing antibodies that limit efficacy following repeat dosing to ferret lungsMolecular Therapy - Methods & Clinical Development, Vol. 29Immune responses in the mammalian inner ear and their implications for AAV-mediated inner ear gene therapyHearing Research, Vol. 432Nucleic Acid Delivery to the Vascular Endothelium17 October 2022 | Molecular Pharmaceutics, Vol. 19, No. 12Gene Therapy for Cardiac Transplantation13 July 2022Approaches to Gene Modulation Therapy for ALS6 September 2022 | Neurotherapeutics, Vol. 19, No. 4Gene therapy: challenges in cell culture scale-upCurrent Opinion in Biotechnology, Vol. 75Durability of transgene expression after rAAV gene therapyMolecular Therapy, Vol. 30, No. 4AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airwayMolecular Therapy, Vol. 30, No. 1Viral vector platforms within the gene therapy landscape8 February 2021 | Signal Transduction and Targeted Therapy, Vol. 6, No. 1Gene Therapy for Duchenne Muscular DystrophyJournal of Neuromuscular Diseases, Vol. 8, No. s2Engineering Gene Therapy: Advances and Barriers20 June 2021 | Advanced Therapeutics, Vol. 4, No. 9Adeno-Associated Vector-Delivered CRISPR/SaCas9 System Reduces Feline Leukemia Virus Production In Vitro18 August 2021 | Viruses, Vol. 13, No. 8Strategies for Targeting Retroviral Integration for Safer Gene Therapy: Advances and Challenges12 May 2021 | Frontiers in Molecular Biosciences, Vol. 8Evolving AAV-delivered therapeutics towards ultimate cures16 February 2021 | Journal of Molecular Medicine, Vol. 99, No. 5Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention8 February 2021 | JCI Insight, Vol. 6, No. 3Development challenges associated with rAAV-based gene therapiesThe Journal of Toxicological Sciences, Vol. 46, No. 2Quantification of Adeno-Associated Virus with Safe Nucleic Acid Dyes Jian Xu, Steven H. 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Johns Hopkins Children's Center, Baltimore, Maryland.Human Gene Therapy.Jun 1996.1145-1159.http://doi.org/10.1089/hum.1996.7.9-1145Published in Volume: 7 Issue 9: March 20, 2008PDF download
Publication Year: 1996
Publication Date: 1996-06-10
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 261
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