Title: A Review of Recent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor Research Activity
Abstract:This non-nucleoside reverse transcriptase inhibitor review covers the patent and published literature from January, 1998-August, 2001. Major advances have been made in the past decade in discovering n...This non-nucleoside reverse transcriptase inhibitor review covers the patent and published literature from January, 1998-August, 2001. Major advances have been made in the past decade in discovering non-nucleoside reverse transcriptase inhibitors that are effective in inhibiting replication of wild-type virus. Attention is now focused upon the discovery of agents that are effective in inhibiting replication of virus with singly and doubly mutated HIV-1 reverse transcriptase. Notable advances in the discovery of such broad spectrum therapeutics are SG-153 and the quinazolines DPC961 and DPC083. Attempts at discovering other broad spectrum anti-viral agents are presented herein. Keywords: Hiv-1 non-nucleoside reverse transcriptase inhibitor, nnrti, stavudineRead More
Publication Year: 2002
Publication Date: 2002-04-01
Language: en
Type: review
Indexed In: ['crossref']
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Cited By Count: 23
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