Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2059646524', 'doi': 'https://doi.org/10.1016/j.psyneuen.2009.03.016', 'title': 'Hypothalamic–pituitary–adrenal axis dysregulation in depressed children and adolescents: A meta-analysis', 'display_name': 'Hypothalamic–pituitary–adrenal axis dysregulation in depressed children and adolescents: A meta-analysis', 'publication_year': 2009, 'publication_date': '2009-05-06', 'ids': {'openalex': 'https://openalex.org/W2059646524', 'doi': 'https://doi.org/10.1016/j.psyneuen.2009.03.016', 'mag': '2059646524', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19406581', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2796553'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.psyneuen.2009.03.016', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S81924583', 'display_name': 'Psychoneuroendocrinology', 'issn_l': '0306-4530', 'issn': ['0306-4530', '1873-3360'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2796553?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5037223745', 'display_name': 'Nestor L. Lopez‐Duran', 'orcid': 'https://orcid.org/0000-0003-0666-496X'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nestor L. Lopez-Duran', 'raw_affiliation_strings': ['University of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, United States of America.'], 'affiliations': [{'raw_affiliation_string': 'University of Pittsburgh School of Medicine, Department of Psychiatry, Pittsburgh, United States of America.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077048656', 'display_name': 'Mária Kovács', 'orcid': 'https://orcid.org/0000-0001-5274-5045'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maria Kovacs', 'raw_affiliation_strings': ['University of Pittsburgh, School of Medicine, Department of Psychiatry, United States.'], 'affiliations': [{'raw_affiliation_string': 'University of Pittsburgh, School of Medicine, Department of Psychiatry, United States.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111606667', 'display_name': 'Charles J. George', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Charles J. George', 'raw_affiliation_strings': ['University of Pittsburgh, School of Medicine, Department of Psychiatry, United States.'], 'affiliations': [{'raw_affiliation_string': 'University of Pittsburgh, School of Medicine, Department of Psychiatry, United States.', 'institution_ids': ['https://openalex.org/I170201317']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3850, 'currency': 'USD', 'value_usd': 3850, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.425, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 397, 'citation_normalized_percentile': {'value': 0.982609, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '34', 'issue': '9', 'first_page': '1272', 'last_page': '1283'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10529', 'display_name': 'Stress Responses and Cortisol', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2802', 'display_name': 'Behavioral Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10529', 'display_name': 'Stress Responses and Cortisol', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2802', 'display_name': 'Behavioral Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11541', 'display_name': 'Neuroendocrine regulation and behavior', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/3207', 'display_name': 'Social Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}, {'id': 'https://openalex.org/T11337', 'display_name': 'Tryptophan and brain disorders', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hypothalamic–pituitary–adrenal-axis', 'display_name': 'Hypothalamic–pituitary–adrenal axis', 'score': 0.7315164}, {'id': 'https://openalex.org/keywords/dexamethasone-suppression-test', 'display_name': 'Dexamethasone suppression test', 'score': 0.6462507}, {'id': 'https://openalex.org/keywords/basal', 'display_name': 'Basal (medicine)', 'score': 0.5653355}, {'id': 'https://openalex.org/keywords/stressor', 'display_name': 'Stressor', 'score': 0.54857194}, {'id': 'https://openalex.org/keywords/corticotropin-releasing-hormone', 'display_name': 'Corticotropin-releasing hormone', 'score': 0.4378531}, {'id': 'https://openalex.org/keywords/depression', 'display_name': 'Depression', 'score': 0.4228195}], 'concepts': [{'id': 'https://openalex.org/C2779146795', 'wikidata': 'https://www.wikidata.org/wiki/Q1369123', 'display_name': 'Hypothalamic–pituitary–adrenal axis', 'level': 3, 'score': 0.7315164}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.71559}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6623406}, {'id': 'https://openalex.org/C2780455818', 'wikidata': 'https://www.wikidata.org/wiki/Q1207196', 'display_name': 'Dexamethasone suppression test', 'level': 3, 'score': 0.6462507}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.5702703}, {'id': 'https://openalex.org/C2778024521', 'wikidata': 'https://www.wikidata.org/wiki/Q55639806', 'display_name': 'Basal (medicine)', 'level': 3, 'score': 0.5653355}, {'id': 'https://openalex.org/C125370674', 'wikidata': 'https://www.wikidata.org/wiki/Q1527480', 'display_name': 'Stressor', 'level': 2, 'score': 0.54857194}, {'id': 'https://openalex.org/C2778458438', 'wikidata': 'https://www.wikidata.org/wiki/Q386664', 'display_name': 'Corticotropin-releasing hormone', 'level': 3, 'score': 0.4378531}, {'id': 'https://openalex.org/C2776867660', 'wikidata': 'https://www.wikidata.org/wiki/Q1814941', 'display_name': 'Depression (economics)', 'level': 2, 'score': 0.4228195}, {'id': 'https://openalex.org/C2780401358', 'wikidata': 'https://www.wikidata.org/wiki/Q422252', 'display_name': 'Dexamethasone', 'level': 2, 'score': 0.36498553}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.29411483}, {'id': 'https://openalex.org/C70410870', 'wikidata': 'https://www.wikidata.org/wiki/Q199906', 'display_name': 'Clinical psychology', 'level': 1, 'score': 0.28597683}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.21413258}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C162324750', 'wikidata': 'https://www.wikidata.org/wiki/Q8134', 'display_name': 'Economics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C139719470', 'wikidata': 'https://www.wikidata.org/wiki/Q39680', 'display_name': 'Macroeconomics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003865', 'descriptor_name': 'Depressive Disorder, Major', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D019263', 'descriptor_name': 'Dysthymic Disorder', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D006854', 'descriptor_name': 'Hydrocortisone', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007030', 'descriptor_name': 'Hypothalamo-Hypophyseal System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D010913', 'descriptor_name': 'Pituitary-Adrenal System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000367', 'descriptor_name': 'Age Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003346', 'descriptor_name': 'Corticotropin-Releasing Hormone', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003346', 'descriptor_name': 'Corticotropin-Releasing Hormone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003865', 'descriptor_name': 'Depressive Disorder, Major', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003907', 'descriptor_name': 'Dexamethasone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019263', 'descriptor_name': 'Dysthymic Disorder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006854', 'descriptor_name': 'Hydrocortisone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007030', 'descriptor_name': 'Hypothalamo-Hypophyseal System', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D007030', 'descriptor_name': 'Hypothalamo-Hypophyseal System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010913', 'descriptor_name': 'Pituitary-Adrenal System', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D010913', 'descriptor_name': 'Pituitary-Adrenal System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012737', 'descriptor_name': 'Sex Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013315', 'descriptor_name': 'Stress, Psychological', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013315', 'descriptor_name': 'Stress, Psychological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.psyneuen.2009.03.016', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S81924583', 'display_name': 'Psychoneuroendocrinology', 'issn_l': '0306-4530', 'issn': ['0306-4530', '1873-3360'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2796553', 'pdf_url': 'https://europepmc.org/articles/pmc2796553?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796553', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19406581', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2796553', 'pdf_url': 'https://europepmc.org/articles/pmc2796553?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'score': 0.79, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 75, 'referenced_works': ['https://openalex.org/W1508825618', 'https://openalex.org/W1563481933', 'https://openalex.org/W1612015840', 'https://openalex.org/W182302130', 'https://openalex.org/W1963943711', 'https://openalex.org/W1965739510', 'https://openalex.org/W1969288273', 'https://openalex.org/W1972193475', 'https://openalex.org/W1973119983', 'https://openalex.org/W1981864453', 'https://openalex.org/W1982686484', 'https://openalex.org/W1988112619', 'https://openalex.org/W1989004477', 'https://openalex.org/W1991353592', 'https://openalex.org/W2001006634', 'https://openalex.org/W2003715347', 'https://openalex.org/W2003994681', 'https://openalex.org/W2010449391', 'https://openalex.org/W2011943672', 'https://openalex.org/W2012890086', 'https://openalex.org/W2014289746', 'https://openalex.org/W2017538352', 'https://openalex.org/W2017598240', 'https://openalex.org/W2021634787', 'https://openalex.org/W2024756109', 'https://openalex.org/W2030272615', 'https://openalex.org/W2032538888', 'https://openalex.org/W2033493592', 'https://openalex.org/W2033585778', 'https://openalex.org/W2036151629', 'https://openalex.org/W2038352072', 'https://openalex.org/W2040053981', 'https://openalex.org/W2040744674', 'https://openalex.org/W2040975346', 'https://openalex.org/W2043985373', 'https://openalex.org/W2045200465', 'https://openalex.org/W2047744566', 'https://openalex.org/W2053007325', 'https://openalex.org/W2064015154', 'https://openalex.org/W2074836353', 'https://openalex.org/W2076837989', 'https://openalex.org/W2081948812', 'https://openalex.org/W2084907923', 'https://openalex.org/W2088068432', 'https://openalex.org/W2088379584', 'https://openalex.org/W2091413411', 'https://openalex.org/W2094115622', 'https://openalex.org/W2094859166', 'https://openalex.org/W2096829505', 'https://openalex.org/W2097879830', 'https://openalex.org/W2107168377', 'https://openalex.org/W2116112775', 'https://openalex.org/W2119761620', 'https://openalex.org/W2121358117', 'https://openalex.org/W2126602143', 'https://openalex.org/W2134639622', 'https://openalex.org/W2137625559', 'https://openalex.org/W2144112749', 'https://openalex.org/W2153074769', 'https://openalex.org/W2158326806', 'https://openalex.org/W2162783686', 'https://openalex.org/W2166475459', 'https://openalex.org/W2170210994', 'https://openalex.org/W2171823433', 'https://openalex.org/W2395625506', 'https://openalex.org/W2406182358', 'https://openalex.org/W2406895737', 'https://openalex.org/W2409021924', 'https://openalex.org/W2411040017', 'https://openalex.org/W2412227877', 'https://openalex.org/W2419593263', 'https://openalex.org/W2435625873', 'https://openalex.org/W3142879079', 'https://openalex.org/W4247581045', 'https://openalex.org/W4255987418'], 'related_works': ['https://openalex.org/W83272993', 'https://openalex.org/W49144085', 'https://openalex.org/W3029151032', 'https://openalex.org/W2966285610', 'https://openalex.org/W2158465596', 'https://openalex.org/W2151774672', 'https://openalex.org/W2137579450', 'https://openalex.org/W2055544673', 'https://openalex.org/W2040744674', 'https://openalex.org/W1986584153'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2059646524', 'counts_by_year': [{'year': 2024, 'cited_by_count': 18}, {'year': 2023, 'cited_by_count': 18}, {'year': 2022, 'cited_by_count': 20}, {'year': 2021, 'cited_by_count': 38}, {'year': 2020, 'cited_by_count': 29}, {'year': 2019, 'cited_by_count': 19}, {'year': 2018, 'cited_by_count': 22}, {'year': 2017, 'cited_by_count': 33}, {'year': 2016, 'cited_by_count': 35}, {'year': 2015, 'cited_by_count': 31}, {'year': 2014, 'cited_by_count': 31}, {'year': 2013, 'cited_by_count': 35}, {'year': 2012, 'cited_by_count': 29}], 'updated_date': '2024-12-09T14:14:57.808381', 'created_date': '2016-06-24'}