Publication Information

{'id': 'https://openalex.org/W2059534238', 'doi': 'https://doi.org/10.1111/j.1365-2958.2009.06648.x', 'title': 'The nature of<i>Staphylococcus aureus</i>MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors', 'display_name': 'The nature of<i>Staphylococcus aureus</i>MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors', 'publication_year': 2009, 'publication_date': '2009-03-04', 'ids': {'openalex': 'https://openalex.org/W2059534238', 'doi': 'https://doi.org/10.1111/j.1365-2958.2009.06648.x', 'mag': '2059534238', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19298367'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2958.2009.06648.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2009.06648.x', 'source': {'id': 'https://openalex.org/S102549058', 'display_name': 'Molecular Microbiology', 'issn_l': '0950-382X', 'issn': ['0950-382X', '1365-2958'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2009.06648.x', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5032244635', 'display_name': 'Katy L. Blake', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130828816', 'display_name': 'University of Leeds', 'ror': 'https://ror.org/024mrxd33', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I130828816']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Katy L. Blake', 'raw_affiliation_strings': ['Institute of Molecular and Cellular Biology and Antimicrobial Research Centre, University of Leeds, Leeds, UK.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular and Cellular Biology and Antimicrobial Research Centre, University of Leeds, Leeds, UK.', 'institution_ids': ['https://openalex.org/I130828816']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061329142', 'display_name': 'Alex J. O’Neill', 'orcid': 'https://orcid.org/0000-0003-3222-5493'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': "Alex J. O'Neill", 'raw_affiliation_strings': ['Institute of Molecular and Cellular Biology and Antimicrobial Research Centre,'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular and Cellular Biology and Antimicrobial Research Centre,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068216286', 'display_name': 'Dominique Mengin‐Lecreulx', 'orcid': 'https://orcid.org/0000-0003-3205-0275'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Dominique Mengin‐Lecreulx', 'raw_affiliation_strings': ['Institut de Biochimie et Biophysique Moléculaire et Cellulaire, UMR 8619 CNRS, Université de Paris‐Sud, 91405\u2003Orsay, France.'], 'affiliations': [{'raw_affiliation_string': 'Institut de Biochimie et Biophysique Moléculaire et Cellulaire, UMR 8619 CNRS, Université de Paris‐Sud, 91405\u2003Orsay, France.', 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I204730241']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055099992', 'display_name': 'Peter J. F. Henderson', 'orcid': 'https://orcid.org/0000-0002-9187-0938'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Peter J. F. Henderson', 'raw_affiliation_strings': ['Institute of Membrane and Systems Biology and Antimicrobial Research Centre,'], 'affiliations': [{'raw_affiliation_string': 'Institute of Membrane and Systems Biology and Antimicrobial Research Centre,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046964047', 'display_name': 'Julieanne M. Bostock', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Julieanne M. Bostock', 'raw_affiliation_strings': ['Institute of Molecular and Cellular Biology and Antimicrobial Research Centre,'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular and Cellular Biology and Antimicrobial Research Centre,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027618254', 'display_name': 'Colin J. Dunsmore', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130828816', 'display_name': 'University of Leeds', 'ror': 'https://ror.org/024mrxd33', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I130828816']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Colin J. Dunsmore', 'raw_affiliation_strings': ['School of Chemistry and Antimicrobial Research Centre, University of Leeds, Leeds, LS2\u20039JT, UK.'], 'affiliations': [{'raw_affiliation_string': 'School of Chemistry and Antimicrobial Research Centre, University of Leeds, Leeds, LS2\u20039JT, UK.', 'institution_ids': ['https://openalex.org/I130828816']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033547380', 'display_name': 'Katie J. Simmons', 'orcid': 'https://orcid.org/0000-0003-4846-9097'}, 'institutions': [{'id': 'https://openalex.org/I130828816', 'display_name': 'University of Leeds', 'ror': 'https://ror.org/024mrxd33', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I130828816']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Katie J. Simmons', 'raw_affiliation_strings': ['School of Chemistry and Antimicrobial Research Centre, University of Leeds, Leeds, LS2\u20039JT, UK.'], 'affiliations': [{'raw_affiliation_string': 'School of Chemistry and Antimicrobial Research Centre, University of Leeds, Leeds, LS2\u20039JT, UK.', 'institution_ids': ['https://openalex.org/I130828816']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053440553', 'display_name': 'Colin W. G. Fishwick', 'orcid': 'https://orcid.org/0000-0003-1283-2181'}, 'institutions': [{'id': 'https://openalex.org/I130828816', 'display_name': 'University of Leeds', 'ror': 'https://ror.org/024mrxd33', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I130828816']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Colin W. G. Fishwick', 'raw_affiliation_strings': ['School of Chemistry and Antimicrobial Research Centre, University of Leeds, Leeds, LS2\u20039JT, UK.'], 'affiliations': [{'raw_affiliation_string': 'School of Chemistry and Antimicrobial Research Centre, University of Leeds, Leeds, LS2\u20039JT, UK.', 'institution_ids': ['https://openalex.org/I130828816']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084193524', 'display_name': 'Jennifer A. Leeds', 'orcid': 'https://orcid.org/0000-0003-2244-4713'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jennifer A. Leeds', 'raw_affiliation_strings': ['Infectious Diseases Area, Novartis Institutes for Biomedical Research, Cambridge, MA\u200302139, USA.'], 'affiliations': [{'raw_affiliation_string': 'Infectious Diseases Area, Novartis Institutes for Biomedical Research, Cambridge, MA\u200302139, USA.', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5114016529', 'display_name': 'Ian Chopra', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ian Chopra', 'raw_affiliation_strings': ['Institute of Molecular and Cellular Biology and Antimicrobial Research Centre,'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular and Cellular Biology and Antimicrobial Research Centre,', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.153, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 84, 'citation_normalized_percentile': {'value': 0.999951, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '72', 'issue': '2', 'first_page': '335', 'last_page': '343'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mura', 'display_name': 'Mura', 'score': 0.78901815}, {'id': 'https://openalex.org/keywords/transferase', 'display_name': 'Transferase', 'score': 0.4823503}], 'concepts': [{'id': 'https://openalex.org/C2776634448', 'wikidata': 'https://www.wikidata.org/wiki/Q206920', 'display_name': 'Peptidoglycan', 'level': 3, 'score': 0.9665285}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8487942}, {'id': 'https://openalex.org/C2776147852', 'wikidata': 'https://www.wikidata.org/wiki/Q6937160', 'display_name': 'Mura', 'level': 3, 'score': 0.78901815}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.644457}, {'id': 'https://openalex.org/C553450214', 'wikidata': 'https://www.wikidata.org/wiki/Q851162', 'display_name': 'Biosynthesis', 'level': 3, 'score': 0.62165284}, {'id': 'https://openalex.org/C2779489039', 'wikidata': 'https://www.wikidata.org/wiki/Q188121', 'display_name': 'Staphylococcus aureus', 'level': 3, 'score': 0.619812}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.52248365}, {'id': 'https://openalex.org/C2776376580', 'wikidata': 'https://www.wikidata.org/wiki/Q407355', 'display_name': 'Transferase', 'level': 3, 'score': 0.4823503}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.4657147}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.4466213}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.14409626}, {'id': 'https://openalex.org/C128019096', 'wikidata': 'https://www.wikidata.org/wiki/Q83341', 'display_name': 'Liquid-crystal display', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019883', 'descriptor_name': 'Alkyl and Aryl Transferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010457', 'descriptor_name': 'Peptidoglycan', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D019883', 'descriptor_name': 'Alkyl and Aryl Transferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019883', 'descriptor_name': 'Alkyl and Aryl Transferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005578', 'descriptor_name': 'Fosfomycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005578', 'descriptor_name': 'Fosfomycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005798', 'descriptor_name': 'Genes, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010457', 'descriptor_name': 'Peptidoglycan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017384', 'descriptor_name': 'Sequence Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2958.2009.06648.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2009.06648.x', 'source': {'id': 'https://openalex.org/S102549058', 'display_name': 'Molecular Microbiology', 'issn_l': '0950-382X', 'issn': ['0950-382X', '1365-2958'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19298367', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2958.2009.06648.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2009.06648.x', 'source': {'id': 'https://openalex.org/S102549058', 'display_name': 'Molecular Microbiology', 'issn_l': '0950-382X', 'issn': ['0950-382X', '1365-2958'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.5, 'id': 'https://metadata.un.org/sdg/15', 'display_name': 'Life on land'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1479743133', 'https://openalex.org/W1558571934', 'https://openalex.org/W1577742856', 'https://openalex.org/W1839855594', 'https://openalex.org/W1901118952', 'https://openalex.org/W1964141703', 'https://openalex.org/W1965760881', 'https://openalex.org/W1971961760', 'https://openalex.org/W1979089302', 'https://openalex.org/W1995405638', 'https://openalex.org/W1999589592', 'https://openalex.org/W2013319822', 'https://openalex.org/W2015642465', 'https://openalex.org/W2029584311', 'https://openalex.org/W2051135826', 'https://openalex.org/W2051192457', 'https://openalex.org/W2053543821', 'https://openalex.org/W2060836091', 'https://openalex.org/W2069420516', 'https://openalex.org/W2098829256', 'https://openalex.org/W2110336020', 'https://openalex.org/W2111993374', 'https://openalex.org/W2115317294', 'https://openalex.org/W2119629693', 'https://openalex.org/W2130150648', 'https://openalex.org/W2138081694', 'https://openalex.org/W2151693231', 'https://openalex.org/W2152301430', 'https://openalex.org/W2157220975', 'https://openalex.org/W2161945811', 'https://openalex.org/W2164997719', 'https://openalex.org/W2166676445', 'https://openalex.org/W2167925521'], 'related_works': ['https://openalex.org/W4386322441', 'https://openalex.org/W4285891574', 'https://openalex.org/W4250391367', 'https://openalex.org/W2987133734', 'https://openalex.org/W2569210251', 'https://openalex.org/W2109929344', 'https://openalex.org/W2059534238', 'https://openalex.org/W2000341751', 'https://openalex.org/W1979703273', 'https://openalex.org/W1523447849'], 'abstract_inverted_index': {'Staphylococcus': [0], 'aureus': [1, 37, 107], 'and': [2, 13, 33, 38, 46, 51, 101], 'a': [3], 'number': [4], 'of': [5, 26, 48, 105, 115, 123, 144, 174], 'other': [6], 'Gram-positive': [7], 'organisms': [8], 'harbour': [9], 'two': [10], 'genes': [11], '(murA': [12], 'murZ)': [14], 'encoding': [15], 'UDP-N-acetylglucosamine': [16], 'enolpyruvyl': [17], 'transferase': [18], 'activity': [19], 'for': [20, 68, 151, 163], 'catalysing': [21], 'the': [22, 49, 69, 79, 84, 102, 175], 'first': [23], 'committed': [24], 'step': [25], 'peptidoglycan': [27, 103, 145, 169], 'biosynthesis.': [28], 'We': [29], 'independently': [30], 'inactivated': [31], 'murA': [32, 88], 'murZ': [34, 96, 132], 'in': [35, 60, 83, 155], 'S.': [36, 106], 'established': [39], 'that': [40, 55], 'either': [41], 'can': [42], 'sustain': [43], 'viability.': [44], 'Purification': [45], 'characterization': [47], 'MurA': [50, 75], 'MurZ': [52], 'enzymes': [53], 'indicated': [54], 'they': [56], 'are': [57], 'biochemically': [58], 'similar': [59, 64], 'vitro,': [61], 'consistent': [62], 'with': [63], 'overall': [65], 'structures': [66], 'predicted': [67], 'isozymes': [70], 'by': [71, 110], 'molecular': [72], 'modelling.': [73], 'Nevertheless,': [74], 'appears': [76], 'to': [77, 138, 142], 'be': [78], 'primary': [80], 'enzyme': [81], 'utilized': [82], 'staphylococcal': [85], 'cell.': [86], 'Accordingly,': [87], 'expression': [89, 97, 128, 133], 'was': [90, 108, 134, 148], 'approximately': [91, 111], 'five': [92], 'times': [93], 'greater': [94], 'than': [95], 'during': [98, 129], 'exponential': [99], 'growth,': [100, 131], 'content': [104], 'reduced': [109], '25%': [112], 'following': [113, 121, 140], 'inactivation': [114, 122], 'murA,': [116], 'but': [117], 'remained': [118], 'almost': [119], 'unchanged': [120], 'murZ.': [124], 'Despite': [125], 'low': [126], 'level': [127], 'normal': [130], 'strongly': [135], 'induced': [136], '(up': [137], 'sixfold)': [139], 'exposure': [141], 'inhibitors': [143, 173], 'biosynthesis,': [146], 'which': [147], 'not': [149], 'observed': [150], 'murA.': [152], 'Strains': [153], 'generated': [154], 'this': [156], 'study': [157], 'were': [158], 'validated': [159], 'as': [160], 'potential': [161], 'tools': [162], 'identifying': [164], 'novel': [165], 'anti-staphylococcal': [166], 'agents': [167], 'targeting': [168], 'biosynthesis': [170], 'using': [171], 'known': [172], 'pathway.': [176]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2059534238', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-09T12:36:13.835574', 'created_date': '2016-06-24'}