Prediction of Capsular Perforation and Seminal Vesicle Invasion in Prostate Cancer

Name: Work Video:
Duration: 3 min 30 s
David G. Bostwick; Junqi Qian; Erik J. Bergstralh; Paul A. Dundore; Dugan James; Robert P. Myers; Joseph E. Oesterling
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'nerve': [119], 'sparing': [120], 'radical': [121, 191, 358, 411, 473, 583, 634, 744, 767, 958, 1005, 1048], 'prostatectomy': [122, 193, 205, 373, 499, 584, 746, 769, 959, 1049], 'watchful': [124], 'waiting.': [125], 'However,': [126], 'current': [127], 'methods': [128], 'imprecise': [130], 'at': [131, 1004], 'predicting': [132], 'the': [133, 150, 172, 272, 296, 312, 316, 348, 362, 461, 488, 495, 548, 701, 712, 715, 775, 791, 833, 922, 946, 952, 957, 997, 1058, 1077, 1123, 1175, 1300, 1803], 'presence': [134], 'extent': [136, 1023], 'factors.': [139], 'We': [140, 170], 'determined': [141], 'which': [142], 'combination': [143, 301, 330], 'commonly': [145], 'available': [146], 'variables': [148, 236, 383], 'provides': [149, 315], 'best': [151, 317], 'capsular': [154, 239, 282, 320, 1050], 'with': [162, 182, 545, 614, 631, 698, 751, 821, 828, 884, 906, 992, 1174], 'localized': [164, 615, 830], 'Materials': [167], 'Methods:': [169], 'reviewed': [171], 'medical': [174], 'records': [175], 'biopsy': [177, 273, 297, 313, 947, 1046], 'findings': [178, 630, 1019], 'from': [179], '314': [180], 'clinical': [183, 255, 526, 603, 811, 1018, 1053], 'stages': [184], 'T1cN0M0': [185], 'T2cN0M0': [187], 'cancer': [188, 270, 294, 310, 405, 864, 944, 955, 994, 1096, 1173], 'who': [189], 'underwent': [190], 'retropubic': [192, 635, 745, 768], 'bilateral': [195], 'pelvic': [196, 741, 764, 1001], 'lymphadenectomy': [197, 742, 765], 'between': [198, 1040], 'September': [199], '1991': [200], 'June': [202], '1993.': [203], 'Radical': [204, 372, 498, 559], 'specimens': [206, 314], 'were': [207, 248, 288], 'embedded': [208], 'evaluated': [210], 'by': [211, 361, 655, 794, 865, 1099, 1129, 1205, 1833, 1844, 1851, 1858, 1865, 1872, 1880, 1900], 'whole': [212], 'mount': [213], 'sections.': [214], 'Results:': [215], 'was': [218, 229], 'observed': [219], '104': [221], '(33.1': [223], 'percent)': [224], 'noted': [230], '46': [232], '(14.6': [233], 'percent).': [234], 'Preoperative': [235], 'predictive': [237], 'on': [245, 328, 387, 961, 1044, 1802], 'univariate': [246], 'analysis': [247, 277], 'serum': [249, 303, 513, 813], 'specific': [251, 485, 601, 798], 'antigen': [252, 486, 515, 880, 919], '(PSA)': [253, 920], 'concentration,': [254, 305], 'stage,': [256, 604, 812], 'Gleason': [257, 262, 290, 306, 606, 819], 'primary': [258], 'secondary': [260], 'patterns,': [261], 'score,': [263], 'nuclear': [264], 'grade,': [265], 'perineural': [266, 1041, 1073], 'percent': [269, 293, 309], 'specimens.': [274, 298], 'On': [275], 'multivariate': [276], 'independent': [278], 'PSA,': [289], 'score': [291, 307, 607], 'Conclusions:': [299], 'The': [300, 597, 646, 688, 844, 876, 896, 940, 1070, 1227], 'PSA': [304, 409], 'invasion.': [325], 'Models': [326], 'based': [327], 'this': [329, 1845, 1852, 1859, 1866, 1873, 1881, 1901], 'may': [333], 'stratify': [338], 'nonoperative': [341], 'treatment.': [342, 447], 'References': [343], '1': [344], ':': [345, 371, 396, 421, 436, 457, 483, 509, 537, 558, 575, 596, 626, 645, 667, 687, 709, 739, 762, 783, 808, 843, 857, 875, 895, 914, 939, 973, 986, 1015, 1038, 1069, 1091, 1114, 1140, 1168, 1453], 'Carcinoma': [346], 'prostate:': [349], 'evaluation': [351], 'certain': [353], 'pathologic': [354, 375, 382, 519, 610, 629, 823], 'features': [355], '208': [357], 'prostatectomies.': [359], 'Examined': [360], 'step-section': [363], 'technique.': [364], 'Cancer1972;': [365], '30:': [366], '5.': [367], 'Google': [368, 393, 418, 433, 454, 480, 506, 534, 555, 572, 593, 623, 642, 664, 684, 706, 736, 759, 780, 805, 840, 854, 872, 892, 911, 936, 970, 983, 1012, 1035, 1066, 1088, 1111, 1137, 1165, 1186], 'Scholar': [369, 394, 419, 434, 455, 481, 507, 535, 556, 573, 594, 624, 643, 665, 685, 707, 737, 760, 781, 806, 841, 855, 873, 893, 912, 937, 971, 984, 1013, 1036, 1067, 1089, 1112, 1138, 1166, 1187], '2': [370], 'stage': [376, 520, 527, 611, 771, 787, 824, 1054], 'C': [377, 772, 1430, 1519], 'cancer:': [379], 'influence': [380, 469], 'adjuvant': [385], 'treatment': [386, 491], 'disease': [388], 'outcome.': [389], 'Urology1993;': [390, 531], '42:': [391], '283.': [392], '3': [395, 1640], 'Systematic': [397], 'biopsies': [398, 1121], 'accurately': [399], 'predict': [400, 518, 609, 951, 1021], 'extracapsular': [401], 'extension': [402, 995], 'persistent/recurrent': [407], 'detectable': [408], 'after': [410, 472, 633], 'prostatectomy.': [412, 636, 1006], 'Urology1994;': [413, 1183], '44:': [414], '371.': [415], 'Crossref,': [416, 431, 640, 1033], 'Medline,': [417, 432, 641, 1034], '4': [420], 'Patterns': [422], 'progression': [424, 632], 'Lancet1986;': [428], '1:': [429], '60.': [430, 982], '5': [435], 'penetration': [438, 1051], 'Significance': [442, 538], 'natural': [444], 'history': [445], 'Amer.': [448, 658, 1060], 'J.': [449, 476, 502, 551, 567, 588, 618, 659, 679, 731, 800, 835, 965, 1007, 1061, 1083, 1132, 1161], 'Surg.': [450, 660, 979, 1062], 'Path.1990;': [451], '14:': [452], '240.': [453], '6': [456, 1553], 'Does': [458], 'microinvasion': [459], 'capsule': [462], 'and/or': [463], 'micrometastases': [464], 'regional': [466, 752], 'lymph': [467, 753], 'nodes': [468], 'disease-free': [470], 'survival': [471, 577], 'prostatectomy?.': [474], 'Brit.': [475, 550], 'Urol.1990;': [477, 552, 680], '66:': [478], '177.': [479], '7': [482], 'diagnosis': [489], 'adenocarcinoma': [493, 699, 748, 773, 831, 1056], 'prostate.': [496, 549, 702, 776, 834, 1059], 'II.': [497], 'treated': [500], 'patients.': [501], 'Urol.1989;': [503, 1084], '11:': [504], '1076.': [505], '8': [508], 'Ability': [510], 'prostate-specific': [514, 879, 918], 'value': [516], 'DNA': [522], 'ploidy.': [523], 'Influence': [524], 'tumor': [529, 722, 1022, 1042], 'grade.': [530], '41:': [532], '207.': [533], '9': [536], 'histological': [540], 'indicators': [542], 'carcinoma': [546, 789], '65:': [553], '46.': [554], '10': [557, 1546], 'prostatectomy:': [560], 'anatomical': [561], 'predictors': [562], 'success': [564], 'or': [565], 'failure.': [566], 'Urol.1986;': [568, 589], '136:': [569, 590], '1041.': [570], 'Link,': [571, 592, 683, 735, 804, 969, 1011, 1087, 1136], '11': [574], 'Patient': [576], 'local': [579, 1078], 'recurrence': [580], 'rate': [581], 'following': [582], 'prostatic': [586, 677, 814, 863, 1081], 'carcinoma.': [587], '422.': [591], '12': [595], 'use': [598, 877, 1176], 'antigen,': [602], 'men': [613], 'Urol.1993;': [619, 732, 1008, 1133], '150:': [620, 1009], '110.': [621], 'Abstract,': [622, 839], '13': [625], 'Correlation': [627, 809], 'Cancer1993;': [637], '71:': [638], '3582.': [639], '14': [644], 'mechanisms': [647], 'significance': [650, 671, 691], 'involvement': [654], 'Path.1993;': [661, 1063], '17:': [662, 1064], '1252.': [663], '15': [666], 'Pathogenesis': [668], 'biological': [670], 'adenocarcinoma.': [678, 1082], '143:': [681], '1183.': [682], '16': [686], 'incidence': [689], 'Cancer1987;': [703], '59:': [704], '1535.': [705], '17': [708], 'Adenocarcinoma': [710, 1231], 'invading': [714], 'vesicle:': [717], 'definition': [718], 'relation': [720], 'volume,': [723], 'grade': [724, 820], 'margins': [726], 'resection': [728], 'prognosis.': [730], '149:': [733, 1134], '1040.': [734], '18': [738], 'Bilateral': [740, 763], 'node': [754, 1002], 'involvement.': [755], 'Urology1982;': [756], '19:': [757], '238.': [758], '19': [761], 'Urology1984;': [777], '24:': [778], '532.': [779], '20': [782], 'Tumor': [784], 'volume': [785, 941], 'detected': [793, 1098], 'elevations': [795], 'antigen.': [799], 'Urol.1994;': [801], '152:': [802], '129.': [803, 853], '21': [807], 'acid': [815], 'phosphatase': [816], 'final': [822], '275': [826], 'Urol.1987;': [836], '138:': [837], '92.': [838], '22': [842], 'TNM': [845], 'classification': [846], 'Prostate,': [850], 'suppl.1992;': [851], '4:': [852], '23': [856], 'Case-control': [858], 'study': [859], 'screening': [861], 'digital': [866], 'rectal': [867], 'examinations.': [868], 'Lancet1991;': [869], '337:': [870], '1526.': [871], '24': 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[1031], '368.': [1032], '31': [1037], 'Relationship': [1039], 'needle': [1045, 1105], 'B': [1055], '336.': [1065], '32': [1068], 'role': [1071], 'space': [1074], 'spread': [1079], '142:': [1085], '763.': [1086], '33': [1090], 'Potential': [1092], 'markers': [1093], 'aggressiveness': [1097], 'fluorescence': [1100], 'situ': [1102], 'hybridization': [1103], 'biopsies.': [1106], 'Res.1994;': [1108], '54:': [1109], '3574.': [1110], '34': [1113], 'Efficacy': [1115], 'transrectal': [1117], 'ultrasound-guided': [1118], 'detection': [1124], '1035.': [1135], '35': [1139], 'Comparison': [1141], 'magnetic': [1143], 'resonance': [1144], 'imaging': [1145], 'ultrasonography': [1147], 'early': [1150], 'Results': [1153], 'a': [1155], 'multi-institutional': [1156], 'cooperative': [1157], 'trial.': [1158], 'New': [1159], 'Engl.': [1160], 'Med.1990;': [1162], '323:': [1163], '621.': [1164], '36': [1167], 'Molecular': [1169], 'enhanced': [1179], 'reverse': [1180], 'transcriptase-PCR': [1181], 'assay.': [1182], '43:': [1184], '765.': [1185], 'Departments': [1188], 'Pathology': [1190], 'Urology,': [1192, 1237, 1273, 1309, 1355, 1385, 1409, 1459, 1498, 1549, 1592, 1636, 1669, 1704, 1750, 1780, 1813, 1890], 'Section': [1194], 'Biostatistics,': [1196], 'Mayo': [1197, 1200], 'Clinic': [1198], 'Foundation,': [1201], 'Rochester,': [1202], 'Minnesota©': [1203], '1996': [1204, 1832], 'American': [1206, 1834], 'Urological': [1207, 1835], 'Association,': [1208, 1836], 'Inc.FiguresReferencesRelatedDetailsCited': [1209], 'bySOFER': [1210], 'M,': [1211, 1213, 1512, 1514, 1602, 1608, 1722], 'SAVOIE': [1212], 'KIM': [1214], 'S,': [1215, 1287], 'CIVANTOS': [1216], 'F': [1217, 1251], 'SOLOWAY': [1219], 'M': [1220, 1294, 1400, 1516, 1796], '(2018)': [1221, 1255, 1295, 1331, 1369, 1401, 1431, 1483, 1520, 1571, 1618, 1652, 1687, 1728, 1766, 1800], 'Biochemical': [1222], 'And': [1223], 'Pathological': [1224, 1304], 'Predictors': [1225], 'Of': [1226, 1229, 1297], 'Recurrence': [1228], 'Prostatic': [1230], 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