Publication Information

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3859, 4074, 4162, 4236, 4282], 'critical': [4, 212, 1021, 3336], 'role': [5, 213, 1625], 'in': [6, 109, 165, 214, 317, 373, 429, 452, 501, 513, 520, 681, 691, 986, 1191, 1240, 1465, 1596, 1630, 1634, 1766, 1800, 1851, 1858, 1954, 1982, 2027, 2069, 2110, 2205, 2304, 2325, 2352, 2410, 2753, 2945, 3072, 3150, 3327, 3339, 3447, 3471, 3868, 3897, 3981, 4039, 4049, 4131, 4187], 'NF-κB': [7, 157, 215, 365, 667, 823, 835, 991, 1111, 1616, 2675, 2699], 'activation.': [8, 216, 1617], 'Diverse': [9, 217], 'stimuli': [10, 218, 433, 735, 767, 1002], 'appear': [11, 42, 219, 250], 'to': [12, 65, 86, 220, 273, 294, 431, 506, 545, 818, 857, 934, 1199, 1488, 1615, 1771, 2181, 2254, 2289, 2542, 2692, 2967, 2986, 3009, 3566, 3582, 3601, 3828, 4073, 4119, 4176], 'utilize': [13, 221], 'reactive': [14, 222, 419, 443, 754], 'oxygen': [15, 223, 420, 444, 755], 'species': [16, 224, 421, 756, 2170, 2756], '(e.g.': [17, 225, 3594], 'hydrogen': [18, 226, 1233, 3741], 'peroxide)': [19, 227], 'as': [20, 57, 187, 199, 228, 265, 395, 407, 423, 435, 556, 558, 759, 936, 1004, 1600, 1686, 1829, 2018, 2323, 2424, 2518, 2561, 2697, 2734, 3359, 3738, 3858, 4052], 'common': [21, 229, 761], 'effectors': [22, 230], 'for': [23, 49, 111, 190, 231, 257, 319, 398, 484, 764, 861, 1001, 1093, 1110, 1431, 1514, 1626, 1809, 1919, 2097, 2132, 2251, 2275, 2317, 3013, 3362, 3460, 3538, 3555, 3787, 3792, 4002, 4062, 4084, 4181, 4239], 'activating': [24, 232], 'NF-κB.': [25, 58, 207, 233, 266, 415, 666, 750], 'Antioxidants': [26, 234, 1044], 'govern': [27, 235, 1045], 'intracellular': [28, 112, 236, 320, 495, 539, 1046, 1493], 'redox': [29, 50, 152, 237, 258, 360, 540, 1047, 1095, 1193, 1504, 1611, 2944], 'status,': [30, 238], 'and': [31, 239, 428, 458, 479, 516, 554, 745, 813, 846, 1009, 1053, 1183, 1242, 1443, 1460, 1490, 1692, 1742, 1786, 1813, 1821, 1848, 1886, 1890, 1932, 1952, 2010, 2036, 2088, 2095, 2117, 2139, 2174, 2176, 2185, 2195, 2242, 2246, 2270, 2294, 2343, 2367, 2378, 2385, 2398, 2409, 2488, 2511, 2538, 2555, 2614, 2618, 2680, 2702, 2707, 2711, 2717, 2728, 2761, 3154, 3229, 3233, 3274, 3350, 3454, 3551, 3560, 3579, 3598, 3791, 3806, 3819, 3824, 3871, 3925, 3951, 3959, 3966, 3971, 4014, 4042, 4111, 4145, 4263, 4273], 'many': [32, 240, 2754, 3445], 'such': [33, 56, 241, 264, 422, 434, 1003, 1221, 4051], 'molecules': [34, 242], 'can': [35, 243, 748, 3094, 4166], 'reduce': [36, 244], 'H2O2.': [37, 245], 'However,': [38, 246, 3931], 'functionally,': [39, 247], 'it': [40, 248, 3581], 'does': [41, 249], 'that': [43, 81, 154, 170, 251, 289, 362, 378, 491, 678, 816, 828, 852, 1086, 1103, 1195, 1231, 1435, 1503, 1583, 1613, 3091, 3183, 3221, 3987, 4011, 4261], 'different': [44, 252, 1087, 2169, 2182, 3938, 4063], 'antioxidants': [45, 253, 480, 1088], 'are': [46, 254, 1187, 1237, 2696, 2750, 4147], 'variously': [47, 255], 'selective': [48, 256], 'regulation': [51, 259, 493], 'of': [52, 84, 128, 135, 162, 203, 206, 260, 292, 336, 343, 370, 411, 414, 462, 488, 494, 560, 671, 675, 734, 822, 834, 840, 939, 989, 998, 1015, 1099, 1397, 1403, 1406, 1474, 1495, 1518, 1621, 1664, 1710, 1739, 1811, 1861, 1907, 1915, 1927, 2000, 2007, 2171, 2208, 2259, 2347, 2552, 2724, 2943, 2948, 2971, 3084, 3103, 3121, 3163, 3180, 3238, 3318, 3364, 3571, 3615, 3624, 3815, 3865, 3885, 3996, 4006, 4086, 4124, 4161, 4214, 4224, 4231, 4255], 'certain': [53, 261], 'transcription': [54, 262, 676], 'factors': [55, 263, 677], 'For': [59, 267], 'NF-κB,': [60, 268, 1016], 'thioredoxin': [61, 91, 120, 197, 269, 299, 328, 405, 577, 582, 1054, 1104, 1181, 1184, 1476, 1606, 1628, 3736, 3817, 3862], 'has': [62, 106, 270, 314, 542, 849, 930, 3184, 3191, 3222, 3240, 3881], 'been': [63, 94, 107, 271, 302, 315, 543, 850, 932, 1413, 2493, 2621, 3357], 'described': [64, 272, 1830, 2425, 2494, 2519, 2562, 2622], 'be': [66, 274, 1507, 2987, 3602, 3990], 'more': [68, 276, 4046], 'potent': [69, 277, 1108], 'antioxidant': [70, 122, 192, 278, 330, 400, 449, 1109, 3249, 3569, 3613, 3834], 'than': [71, 279], 'either': [72, 176, 280, 384, 3227, 4094, 4198], 'glutathione': [73, 281, 2334], 'orN-acetylcysteine.': [74, 282], 'Thioredoxin': [75, 283, 1178, 1235], 'peroxidase': [76, 198, 284, 406, 1185, 1477, 1629, 2407, 3689, 3795], 'is': [77, 141, 173, 285, 349, 381, 481, 508, 665, 668, 824, 1078, 1083, 1105, 1227, 1487, 1603, 3146, 3158, 3171, 3201, 3325, 3542, 3621, 3684, 3894, 4233], 'the': [78, 133, 166, 286, 341, 374, 459, 492, 672, 682, 819, 858, 990, 1012, 1073, 1081, 1228, 1470, 1492, 1501, 1635, 1657, 1661, 1677, 1688, 1698, 1743, 1748, 1772, 1933, 2020, 2118, 2126, 2271, 2291, 2295, 2318, 2344, 2556, 2681, 2969, 2992, 3014, 3085, 3104, 3115, 3125, 3149, 3161, 3164, 3334, 3344, 3442, 3461, 3539, 3556, 3568, 3612, 3622, 3813, 3932, 3994, 4003, 4012, 4032, 4121, 4135, 4151, 4159, 4178, 4188, 4222, 4225], 'immediate': [79, 201, 287, 409, 1229], 'enzyme': [80, 123, 288, 331, 1230, 1592], 'links': [82, 290], 'reduction': [83, 291, 1198], 'H2O2': [85, 293, 424, 809], 'thioredoxin.': [87, 295], 'Several': [88, 296, 486], 'putative': [89, 297, 1409, 3223], 'human': [90, 119, 147, 298, 327, 355, 569, 602, 1475, 1515, 1605, 1627, 1643, 1791, 2001, 2008, 2014, 2972, 3015, 3323, 3341, 3861, 3869, 3900, 4174], 'peroxidases': [92, 300, 1236], 'have': [93, 301, 447, 752, 1090, 1101, 1412, 1425, 2491, 2620, 3356], 'identified': [95, 125, 303, 333, 1414, 3078], 'using': [96, 304, 1680, 1747, 2043, 2165, 2339, 3118], 'recursive': [97, 305], 'sequence': [98, 306, 1416, 1653, 3130, 3167, 3237, 3472, 4085], 'searches/alignments': [99, 307], 'with': [100, 132, 180, 308, 340, 388, 440, 686, 1419, 1697, 1715, 1782, 1789, 1912, 1949, 1994, 2075, 2093, 2103, 2120, 2147, 2154, 2198, 2313, 2359, 2601, 3114, 3187, 3203, 3243, 3320, 3821, 3940, 4026, 4093, 4150, 4197, 4211, 4235, 4266], 'yeast': [101, 309, 1420, 1573, 1767, 2489, 2993, 3247], 'or': [102, 178, 310, 386, 1421, 1472, 2362, 2416, 3231, 4101, 4206], 'prokaryotic': [103, 311], 'enzymes.': [104, 312, 1423, 1499], 'None': [105, 313], 'characterized': [108, 316, 3831, 4270, 4284], 'detail': [110, 318], 'function(s).': [113, 321], 'Here,': [114, 322, 3735], 'we': [115, 323, 1512, 1576, 2990, 3077, 3610, 3999, 4068, 4172], 'describe': [116, 324], 'new': [118, 326, 1429, 1586, 1598, 3528, 3535], 'peroxidase,': [121, 329], 'AOE372,': [124, 332, 2002, 4067], 'by': [126, 334, 1415, 1660, 1676, 1892, 1903, 1944, 2033, 2052, 2144, 2164, 2372, 2393, 2399, 2611, 3473, 3591, 3629, 3686, 3876, 4126, 4251], 'virtue': [127, 335], 'its': [129, 337, 3197], 'protein-protein': [130, 338, 1510, 3011], 'interaction': [131, 339], 'product': [134, 342], 'proliferation': [137, 345], 'associationgene,': [138, 346], 'pag,': [139, 347], 'which': [140, 348, 1007, 3200], 'also': [142, 350, 931, 2492, 4000], 'thiol-specific': [144, 352, 1498, 1521, 3016, 3248, 3549, 3833], 'antioxidant.': [145, 353], 'In': [146, 354, 536, 981, 1220, 3124, 3797, 4031], 'cells,': [148, 356, 538, 1050, 1225], 'AOE372': [149, 171, 194, 357, 379, 402, 1593, 1608, 1622, 1637, 1669, 2321, 2349, 2363, 2366, 3170, 3190, 3239, 3319, 3332, 3448, 3520, 3540, 3588, 3800, 3810, 3857, 3866, 3879, 3892, 3976, 4013, 4044, 4079, 4105, 4125, 4183, 4232, 4262], 'defines': [150, 358, 1609], 'pathway': [153, 361, 833, 860, 1612], 'specifically': [155, 363, 1107, 4092], 'regulates': [156, 364], 'activity': [158, 172, 366, 380, 1014, 1620, 3570, 3620, 3690], 'via': [159, 367, 684], 'modulation': [161, 369], 'IκB-α': [163, 371, 841, 1017, 1632], 'phosphorylation': [164, 372, 839, 854, 941, 984, 1633], 'cytoplasm.': [167, 375, 1636], 'We': [168, 376, 3564, 3573, 3783, 4009, 4115], 'show': [169, 377], 'regulated': [174, 382, 1508, 3992], 'through': [175, 383, 1509, 1895, 2333], 'homo-': [177, 385], 'heterodimerization': [179, 387], 'other': [181, 389, 3097, 3462], 'thiol': [182, 390, 3688, 3794], 'peroxidases,': [183, 391], 'implicating': [184, 392], 'subunit': [185, 393], 'assortment': [186, 394], 'mechanism': [189, 397, 512], 'regulating': [191, 399], 'specificities.': [193, 401], 'function': [195, 403, 821], 'suggests': [196, 404, 1399], 'an': [200, 408, 825, 987, 1995, 2314, 3882, 4212], 'regulator': [202, 410], 'H2O2-mediated': [204, 412], 'activation': [205, 413, 559, 836, 1022, 1112], 'Living': [416], 'organisms': [417, 502], 'produce': [418, 2543, 2693], 'during': [425], 'physiological': [426, 1485], 'processes': [427], 'response': [430, 599], 'external': [432], 'UV': [436], 'radiation.': [437], 'To': [438, 3985, 4065], 'cope': [439], 'potentially': [441], 'destructive': [442], 'species,': [445], 'cells': [446, 1850, 2058, 2122, 2192, 2554, 4165, 4175], 'evolved': [448], 'defenses': [450], '(reviewed': [451, 519, 690], 'Ref.': [453, 521], '1Scandalios': [454], 'J.G.': [455, 2625], 'Oxidative': [456], 'Stress': [457], 'Molecular': [460], 'Biology': [461], 'Antioxidant': [463], 'Defenses.': [464], 'Cold': [465, 469], 'Spring': [466, 470], 'Harbor': [467], 'Laboratory,': [468], 'Harbor,': [471], 'NY1997Google': [472], 'Scholar).': [473, 535, 661, 730, 807, 924, 980, 1043, 1177, 1219, 1393, 1570, 1731, 1760, 1845, 2485, 2508, 2534, 2594, 2670, 2748, 2939, 3065, 3313, 3440, 3681, 3734, 3782, 3852], 'A': [474, 731, 1097, 3107, 3617, 3805, 3970], 'delicate': [475], 'balance': [476], 'between': [477, 3937], 'oxidants': [478], 'pivotally': [482], 'important': [483, 826, 3361, 4168], 'homeostasis.': [485], 'lines': [487, 3873, 3902], 'evidence': [489, 1082], 'suggest': [490], 'redox,': [496], 'process': [498], 'highly': [499, 1238, 2751, 3802, 4047], 'conserved': [500, 1239, 2752], 'ranging': [503], 'from': [504, 618, 1641, 1656, 1819, 2168, 2266, 2307, 2355, 3457, 3523, 3627, 4277], 'bacteria': [505, 1422], 'human,': [507, 2758], 'versatile': [510], 'control': [511], 'signal': [514, 762, 994, 3205], 'transduction': [515], 'gene': [517, 2949], 'expression': [518, 1810, 2950, 3933, 4004, 4016, 4060, 4123], '2Sen': [522], 'C.K.': [523, 2952], 'Packer': [524, 2953], 'L.': [525, 908, 1721, 2643, 2954], 'FASEB': [526, 2955], 'J.': [527, 627, 896, 1149, 1166, 1208, 1278, 1298, 1361, 1378, 1453, 1532, 1752, 2432, 2454, 2474, 2741, 2797, 2817, 2880, 2897, 2956, 3027, 3262, 3372, 3425, 3504, 3670, 3697, 3719, 3749, 3841, 4293], '1996;': [528, 718, 912, 968, 1755, 2957, 3407, 3428, 3722], '10:': [529, 629, 2958], '709-720Crossref': [530, 2959], 'PubMed': [531, 631, 657, 708, 726, 778, 803, 878, 900, 920, 976, 1039, 1067, 1133, 1155, 1175, 1217, 1257, 1287, 1307, 1326, 1344, 1366, 1389, 1541, 1566, 1758, 2441, 2463, 2483, 2590, 2634, 2666, 2746, 2776, 2806, 2826, 2845, 2863, 2885, 2908, 2935, 2960, 3004, 3036, 3061, 3141, 3216, 3271, 3309, 3381, 3400, 3410, 3436, 3492, 3515, 3655, 3679, 3706, 3730, 3758, 3778, 3850, 4299], 'Scopus': [532, 632, 658, 709, 727, 779, 804, 879, 901, 921, 977, 1040, 1068, 1134, 1156, 1258, 1327, 1345, 1367, 1390, 1567, 1842, 2505, 2531, 2574, 2591, 2635, 2667, 2777, 2846, 2864, 2886, 2909, 2936, 2961, 3005, 3062, 3142, 3217, 3310, 3401, 3411, 3437, 3493, 3516, 3656, 3731, 3779], '(1781)': [533, 2962], 'Google': [534, 634, 660, 711, 729, 781, 806, 881, 903, 923, 979, 1042, 1070, 1136, 1158, 1176, 1218, 1260, 1288, 1308, 1329, 1347, 1369, 1392, 1542, 1569, 1730, 1759, 1844, 2442, 2464, 2484, 2507, 2533, 2576, 2593, 2637, 2669, 2747, 2779, 2807, 2827, 2848, 2866, 2888, 2911, 2938, 2963, 3007, 3037, 3064, 3144, 3219, 3272, 3312, 3382, 3403, 3413, 3439, 3495, 3518, 3658, 3680, 3707, 3733, 3759, 3781, 3851], 'mammalian': [537, 1432, 2755], 'status': [541], 'linked': [544, 1189], 'cellular': [546, 1516], 'differentiation,': [547], 'immune': [548], 'response,': [549], 'growth': [550], 'control,': [551], 'tumor': [552, 573, 737], 'promotion,': [553], 'apoptosis,': [555], 'well': [557, 4269, 4283], 'viruses,': [561], 'notably': [562], 'HIV,': [563, 568], '1The': [564], 'abbreviations': [565], 'used': [566, 2541, 2691, 2991, 4116], 'are:': [567], 'immunodeficiency': [570], 'virus;': [571, 605], 'TNF,': [572], 'necrosis': [574, 738], 'factor;': [575], 'TR,': [576], 'reductase;': [578], 'Trx,': [579], 'thioredoxin;': [580], 'Tpx,': [581], 'peroxidase;': [583], 'bp,': [584], 'base': [585], 'pair(s);': [586], 'PAGE,': [587], 'polyacrylamide': [588], 'gel': [589, 1956, 2029, 2512], 'electrophoresis;': [590], 'PBS,': [591], 'phosphate-buffered': [592], 'saline;': [593], 'CAT,': [594], 'chloramphenicol': [595], 'acetyltransferase;': [596], 'SRE,': [597, 2679, 2709], 'serum': [598, 4200], 'element;': [600], 'HTLV,': [601], 'T-cell': [603], 'lymphotrophic': [604], 'LTR,': [606], 'long': [607], 'terminal': [608], 'repeat;': [609], 'α-Pag,': [610], 'anti-Pag': [611, 1970], 'antibody;': [612], 'TPA,': [613], '12-O-tetradecanoylphorbol-13-acetate;': [614], 'PDC,': [615], 'paraquat': [616, 2414], 'dichloride.': [617], 'latency': [619], '(3Schreck': [620], 'R.': [621, 1060], 'Rieber': [622], 'P.': [623, 962], 'Baeuerle': [624, 893, 963], 'P.A.': [625, 714, 769, 894, 964], 'EMBO': [626, 895], '1991;': [628, 654], '2247-2258Crossref': [630], '(3430)': [633], 'Scholar,4Kalebic': [635], 'T.': [636, 771, 870, 888, 910, 1139, 1143, 1147, 1161, 1165, 1245, 1263, 1356, 1360, 2764, 2782, 2875, 2879], 'Kinter': [637], 'A.': [638, 644, 653, 799, 950, 1129, 1145, 1322, 1562, 2647, 2662, 2841, 2931, 3057, 3305, 3396, 3488, 3651], 'Poli': [639], 'G.': [640, 1297, 1462, 1531, 1551, 1553, 2651, 2816, 2920, 2922, 3026, 3046, 3048, 3209, 3294, 3296, 3640, 3642], 'Anderson': [641], 'M.E.': [642], 'Meister': [643], 'Fauci': [645], 'A.S.': [646], 'Proc.': [647, 793, 1123, 1316, 1556, 2656, 2835, 2925, 3051, 3299, 3390, 3482, 3645], 'Natl.': [648, 794, 1124, 1317, 1557, 2657, 2836, 2926, 3052, 3300, 3391, 3483, 3646], 'Acad.': [649, 795, 1125, 1318, 1558, 2658, 2837, 2927, 3053, 3301, 3392, 3484, 3647], 'Sci.': [650, 796, 1126, 1319, 1559, 2659, 2838, 2928, 3054, 3302, 3393, 3485, 3648], 'U.': [651, 797, 1127, 1320, 1384, 1560, 2660, 2839, 2903, 2929, 3055, 3303, 3394, 3486, 3510, 3649], 'S.': [652, 702, 798, 892, 1033, 1128, 1249, 1271, 1277, 1321, 1350, 1372, 1461, 1561, 2661, 2768, 2790, 2796, 2840, 2869, 2891, 2930, 2997, 3056, 3304, 3395, 3487, 3498, 3650], '88:': [655], '986-990Crossref': [656], '(319)': [659], 'One': [662, 832, 1481, 1905], 'redox-regulated': [663], 'protein': [664, 1711, 1928, 1980, 2301, 2322, 2330, 2726, 3093, 3176, 3236, 3281, 3576, 4098, 4106, 4122, 4136, 4163], 'member': [670], 'Rel': [673], 'family': [674], 'exist': [679, 4058], 'ambiently': [680], 'cytoplasm': [683, 4189], 'association': [685], 'inhibitor': [687], 'protein,': [688, 4281], 'IκB': [689, 856, 925], 'Refs.': [692], '5Verma': [693], 'I.M.': [694, 1025], 'Stevenson': [695, 1026], 'J.K.': [696, 1027], 'Schwarz': [697, 1028], 'E.M.': [698, 1029], 'Antwerp': [699, 1030], 'D.V.': [700, 1031], 'Miyamoto': [701, 1032], 'Genes': [703, 1034], 'Dev.': [704, 1035], '1995;': [705, 897, 1036, 1064, 1386, 2905, 3512], '9:': [706, 1037], '2723-2735Crossref': [707, 1038], '(1665)': [710, 1041], 'Scholar': [712], 'and6Baeuerle': [713], 'Baltimore': [715], 'D.': [716, 958, 1293, 1527, 2812, 3022], 'Cell.': [717, 871, 911, 967, 2585, 3134], '87:': [719], '13-20Abstract': [720], 'Full': [721, 723, 875, 915, 917, 971, 973, 1172, 1214, 1284, 1304, 1538, 2438, 2460, 2480, 2803, 2823, 3033, 3138, 3268, 3378, 3431, 3433, 3676, 3703, 3725, 3727, 3755, 3847], 'Text': [722, 724, 876, 916, 918, 972, 974, 1173, 1215, 1285, 1305, 1539, 2439, 2461, 2481, 2804, 2824, 3034, 3139, 3269, 3379, 3432, 3434, 3677, 3704, 3726, 3728, 3756, 3848], 'PDF': [725, 877, 919, 975, 1174, 1216, 1286, 1306, 1540, 2440, 2462, 2482, 2805, 2825, 3035, 3140, 3270, 3380, 3435, 3678, 3705, 3729, 3757, 3849], '(2935)': [728], 'wide': [732], 'variety': [733], 'including': [736, 2757, 3246, 3903], 'factor-α': [739], '(TNF-α),': [740], 'phorbol': [741], 'ester,': [742], 'bacterial': [743, 3275], 'lipopolysaccharide,': [744], 'virus': [746], 'infection': [747], 'activate': [749], 'Studies': [751], 'implicated': [753, 3358], '(i.e.': [757, 2413, 3343], 'H2O2)': [758], 'one': [760], 'transducer': [763], 'these': [765, 2694], 'diverse': [766], '(7Baeuerle': [768], 'Henkel': [770, 887], 'Annu.': [772], 'Rev.': [773], 'Immunol.': [774, 1151], '1994;': [775, 800, 872, 1130, 1211, 1323, 1341, 1363, 1563, 2435, 2842, 2860, 2882, 2932, 3058, 3306, 3375, 3397, 3489, 3652, 3700, 3752, 3775, 3844], '12:': [776], '141-179Crossref': [777], '(4602)': [780], 'Scholar,': [782, 882, 904, 1137, 1159, 1261, 1289, 1309, 1330, 1348, 1370, 1543, 2443, 2465, 2577, 2780, 2808, 2828, 2849, 2867, 2889, 2912, 3038, 3383, 3414, 3496, 3659, 3708, 3760], '8Anderson': [783], 'M.T.': [784], 'Staal': [785], 'F.J.T.': [786], 'Gilter': [787], 'C.': [788, 956, 1458], 'Herzenberg': [789, 791], 'L.A.': [790, 792], '91:': [801, 1131, 1324, 1564, 2843, 2933, 3059, 3307, 3398, 3490, 3653], '11527-11531Crossref': [802], '(362)': [805], 'How': [808], 'might': [810, 1506], 'affect': [811], 'cytoplasmic': [812, 4229, 4271], 'nuclear': [814, 992, 996, 1013, 2296, 4285], 'events': [815], 'lead': [817], 'activated': [820], 'issue': [827], 'remains': [829], 'incompletely': [830], 'elucidated.': [831], 'involves': [837], 'site-specific': [838], 'on': [842, 942, 1439, 1673, 1736, 2062, 2113, 2152, 2249, 2381, 2596, 2687], 'serine': [843, 853], 'residues': [844, 3446], '32': [845], '36.': [847], 'It': [848, 1077], 'suggested': [851, 1102, 1427, 3536], 'targets': [855], 'ubiquitin-proteasome': [859], 'degradation': [862], '(9Palombella': [863], 'V.J.': [864], 'Rando': [865], 'O.J.': [866], 'Goldberg': [867], 'A.L.': [868, 1380, 2899, 3506], 'Maniatis': [869, 909], '78:': [873], '773-785Abstract': [874], '(1922)': [880], '10Traenckner': [883], 'E.B.-M.': [884, 954], 'Pahl': [885, 951], 'H.L.': [886, 952], 'Schmidt': [889], 'K.N.': [890], 'Wilk': [891], '14:': [898, 3214], '2876-2883Crossref': [899], '(934)': [902], '11Chen': [905], 'Z.J.': [906], 'Parent': [907], '84:': [913], '853-862Abstract': [914], '(871)': [922], 'inactivation,': [926], 'without': [927], 'proteolytic': [928], 'degradation,': [929], 'reported': [933, 2736], 'occur': [935], 'consequence': [938], 'tyrosine': [940], 'residue': [943], '42': [944], '(12Imbert': [945], 'V.': [946], 'Rupec': [947], 'R.A.': [948], 'Livolsi': [949], 'Traenckner': [953], 'Mueller-Dieckmann': [955], 'Farahifar': [957], 'Rossi': [959], 'B.': [960, 1058, 3330], 'Auberger': [961], 'Peyron': [965], 'J.-F.': [966], '86:': [969], '787-798Abstract': [970], '(627)': [978], 'both': [982, 1674, 3798], 'instances,': [983], 'results': [985, 3854], 'unmasking': [988], 'localization': [993], 'facilitating': [995], 'entry': [997], 'protein.': [999], 'Thus,': [1000, 4056], 'oxidative': [1005], 'stress,': [1006], 'potently': [1008], 'rapidly': [1010], 'modulates': [1011], 'may': [1018], 'represent': [1019, 1072, 3553], 'target': [1023], '(5Verma': [1024], 'status.': [1048], 'Inside': [1049], 'glutathione,': [1051], 'glutaredoxin,': [1052], '(13Thomas': [1055], 'J.A.': [1056], 'Poland': [1057], 'Honzatko': [1059], 'Arch.': [1061], 'Biochem.': [1062, 1362, 2881, 3771], 'Biophys.': [1063, 3772], '319:': [1065], '1-9Crossref': [1066], '(365)': [1069], 'Scholar)': [1071, 2964, 3008, 3145, 3220, 3273], 'major': [1074], 'reducing': [1075, 3592], 'agents.': [1076], 'reasonable,': [1079], 'although': [1080], 'not': [1084, 3979], 'clear-cut,': [1085], 'should': [1089], 'preferential': [1091], 'specificities': [1092], 'discrete': [1094, 3605], 'pathways.': [1096], 'number': [1098, 2065], 'studies': [1100], '(14Schenk': [1113], 'H.': [1114, 1141, 1267, 1352, 1354, 1374, 1449, 1452, 2786, 2871, 2873, 2893, 3500], 'Klein': [1115], 'M.': [1116, 1251, 1265, 1269, 1723, 2770, 2784, 2788, 3133], 'Erdbrugger': [1117], 'W.': [1118, 1120, 1447, 2629, 2641], 'Droge': [1119], 'Schulze-Osthoff': [1121], 'K.': [1122, 1273, 1455, 1547, 2445, 2471, 2792, 2916, 3042, 3259, 3290, 3636, 3661, 3770], '1672-1676Crossref': [1132], '(644)': [1135], '15Okamoto': [1138], 'Ogiwara': [1140], 'Hayashi': [1142], 'Mitsui': [1144], 'Kawabe': [1146], 'Yodoi': [1148], 'Int.': [1150], '1992;': [1152, 4296], '4:': [1153], '811-819Crossref': [1154], '(134)': [1157, 1391, 2910, 3517], '16Hayashi': [1160], 'Ueno': [1162], 'Y.': [1163, 1247, 1275, 1382, 2766, 2794, 2901, 3508], 'Okamoto': [1164], 'Biol.': [1167, 1209, 1279, 1299, 1533, 1725, 2433, 2455, 2475, 2586, 2798, 2818, 3028, 3263, 3373, 3426, 3671, 3698, 3720, 3750, 3842, 4295], 'Chem.': [1168, 1210, 1280, 1300, 1534, 2434, 2456, 2476, 2799, 2819, 3029, 3264, 3374, 3427, 3672, 3699, 3721, 3751, 3843], '1993;': [1169, 1281, 1301, 1535, 2477, 2743, 2800, 2820, 3030, 3265], '268:': [1170, 1282, 1302, 1536, 2478, 2801, 2821, 3031, 3266], '11380-11388Abstract': [1171], 'reductase': [1179, 3279], '(TR),': [1180], '(Trx),': [1182], '(Tpx)': [1186], 'three': [1188, 1947], 'components': [1190], 'chain': [1194, 2980], 'couples': [1196], 'peroxide': [1197], 'NADPH': [1200, 3820], 'oxidation': [1201, 3632], '(17Chae': [1202, 2426, 3366, 3691, 3743, 3835], 'H.Z.': [1203, 1311, 1545, 2427, 2467, 2830, 2914, 3040, 3255, 3288, 3367, 3385, 3418, 3477, 3634, 3692, 3712, 3744, 3836], 'Chung': [1204, 2428, 3368, 3693, 3745, 3837], 'S.J.': [1205, 2429, 3369, 3694, 3746, 3762, 3838], 'Rhee': [1206, 1314, 1554, 2430, 2450, 2472, 2833, 2923, 3049, 3260, 3297, 3370, 3388, 3421, 3480, 3643, 3666, 3695, 3715, 3747, 3839], 'S.G.': [1207, 1315, 1555, 2431, 2451, 2473, 2834, 2924, 3050, 3261, 3298, 3371, 3389, 3422, 3481, 3644, 3667, 3696, 3716, 3748, 3840], '269:': [1212, 2436, 3376, 3701, 3753, 3845], '27670-27678Abstract': [1213, 2437, 3377, 3702, 3754, 3846], 'scheme,': [1223], 'within': [1224], 'Tpx': [1226], 'detoxifies': [1232], 'peroxide.': [1234], 'eukaryotes': [1241], 'prokaryotes': [1243], '(18Yamamoto': [1244, 2763], 'Matsui': [1246, 2765], 'Natori': [1248, 2767], 'Obinata': [1250, 2769], 'Gene': [1252, 1339, 2771, 2858], '(Amst.).': [1253, 1340, 2772, 2859], '1989;': [1254, 2773, 3001], '80:': [1255, 2774], '337-343Crossref': [1256, 2775], '(110)': [1259, 2778], '19Ishii': [1262, 2781], 'Yamada': [1264, 2783], 'Sato': [1266, 2785], 'Matsue': [1268, 2787], 'Taketani': [1270, 2789], 'Nakayama': [1272, 2791], 'Sugita': [1274, 2793], 'Bannai': [1276, 2795], '18633-18636Abstract': [1283, 2802], '20Prosperi': [1290, 2809], 'M.-T.': [1291, 1525, 2810, 3020], 'Ferbus': [1292, 1526, 2811, 3021], 'Karczinski': [1294, 1528, 2813, 3023], 'I.': [1295, 1457, 1529, 2814, 3024, 4290], 'Goubin': [1296, 1530, 2815, 3025], '11050-11056Abstract': [1303, 1537, 2822, 3032], '21Chae': [1310, 2829, 3384], 'Uhm': [1312, 2831, 3386, 3478], 'T.B.': [1313, 2832, 3387, 3479], '7022-7026Crossref': [1325, 2844, 3399, 3491], '(281)': [1328, 2847, 3402, 3494], '22Lim': [1331, 2850], 'Y.-S.': [1332, 2851], 'Cha': [1333, 2852], 'M.-K.': [1334, 2853], 'Kim': [1335, 1337, 2446, 2468, 2470, 2854, 2856, 3256, 3258, 3662, 3767, 3769], 'H.-K.': [1336, 2855], 'I.-H.': [1338, 2469, 2857, 3257], '140:': [1342, 2861], '279-284Crossref': [1343, 2862], '(68)': [1346, 2865], '23Watabe': [1349, 2868], 'Kohno': [1351, 2870], 'Kouyama': [1353, 2872], 'Hiroi': [1355, 2874], 'Yago': [1357, 2876], 'N.': [1358, 2877], 'Nakazawa': [1359, 2878], '115:': [1364, 2883], '648-654Crossref': [1365, 2884], '(99)': [1368, 2887], '24Iwahara': [1371, 2890, 3497], 'Satoh': [1373, 2892, 3499], 'Song': [1375, 2894, 2998, 3501], 'D.-X.': [1376, 2895, 3502], 'Webb': [1377, 2896, 3503], 'Burlingame': [1379, 2898, 3505], 'Nagae': [1381, 2900, 3507], 'Muller-Eberhard': [1383, 2902, 3509], 'Biochemistry.': [1385, 2904, 3406, 3511], '34:': [1387, 2906, 3513], '13398-13406Crossref': [1388, 2907, 3514], 'Their': [1394], 'high': [1395], 'degree': [1396], 'conservation': [1398], 'biological': [1401, 1619], 'importance': [1402, 2942], 'this': [1404, 3546, 3608, 4117], 'type': [1405], 'enzyme.': [1407], 'Some': [1408], '"Tpx"': [1410], 'proteins': [1411, 2369, 2390], 'alignment': [1417, 3317], 'searches': [1418], '2We': [1424], 'recently': [1426], 'nomenclature': [1430, 3537], 'peroxiredoxins,': [1433], 'Prx,': [1434], 'classifies': [1436], 'them': [1437], 'based': [1438, 1735, 2686], 'amino': [1440, 3315], 'acid': [1441, 3175, 3316], 'sequences': [1442, 1694, 1712], 'immunological': [1444], 'reactivities': [1445], '(S.': [1446], 'Kang,': [1448], 'Z.': [1450], 'Chae,': [1451], 'Kim,': [1454, 1456], 'Baines,': [1459], 'Rhee,': [1463], 'manuscript': [1464], 'preparation).': [1466], 'At': [1467, 3441], 'present,': [1468], 'however,': [1469], 'functions': [1471], 'properties': [1473], 'remain': [1478], 'ill': [1479], 'defined.': [1480], 'step': [1482], 'toward': [1483, 4170], 'better': [1484], 'understanding': [1486], 'identify': [1489, 3010, 3856], 'characterize': [1491, 4066], 'activities': [1494], 'bona': [1496], 'fide': [1497], 'With': [1500], 'idea': [1502], 'enzymes': [1505], 'interactions,': [1511], 'searched': [1513], 'partners': [1517, 3012], 'known': [1520, 3244, 3322, 3524, 3618], 'antioxidant,': [1522, 3017], 'Pag': [1523, 1579, 1979, 2342, 2368, 3018, 3092, 4240, 4264], '(20Prosperi': [1524, 3019], '25Chae': [1544, 2913, 3039], 'Robison': [1546, 2915, 3041, 3289, 3635], 'Poole': [1548, 2917, 3043, 3291, 3637], 'L.B.': [1549, 2918, 3044, 3292, 3405, 3638], 'Church': [1550, 2919, 3045, 3293, 3639], 'Storz': [1552, 2921, 3047, 3295, 3641], '7017-7021Crossref': [1565, 2934, 3060, 3308, 3654], '(706)': [1568, 2937, 3063, 3311, 3657], 'Using': [1571, 3607], 'two-hybrid': [1574, 1762, 2994], 'approach,': [1575], 'isolated': [1577, 1640], '(as': [1578], 'partner)': [1580], 'cDNA': [1582, 1638, 1647, 1665, 1670, 1797, 2016, 3075, 3109, 3122], 'encodes': [1584], 'prototype': [1587], 'peroxiredoxin.': [1588, 3189], 'This': [1589, 3682], 'peroxiredoxin,': [1590, 3832], 'designatedantioxidant': [1591], '(and': [1594], 'classified': [1595], 'nomenclature2': [1599], 'subfamily': [1601, 3529, 3541], 'IV),': [1602], 'peroxidase.': [1607, 3863], 'leads': [1614], 'The': [1618, 1650, 2200, 2401, 2940, 3096, 3235, 4228, 4246], 'implicates': [1623], 'modulating': [1631], 'was': [1639, 1654, 1671, 1734, 1745, 1764, 1780, 1817, 1901, 1910, 1930, 1935, 1973, 2203, 2247, 2268, 2273, 2302, 2331, 2599, 2982, 3110, 3589, 3599, 3801, 3874, 3978, 4036, 4045, 4184], 'HeLa': [1644, 1792, 1847, 2057, 2191, 2553, 3074, 3907, 4103], 'S3': [1645, 1793], 'Matchmaker': [1646, 1773, 1796], 'library': [1648, 1659, 1798], '(HL4000A1;CLONTECH).': [1649], '5′': [1651], '95-bp': [1652], 'obtained': [1655], 'same': [1658, 3105, 3443, 4033], 'rapid': [1662], 'amplification': [1663, 3120], 'ends': [1666], 'procedure.': [1667], 'Double-stranded': [1668], 'sequenced': [1672], 'strands': [1675], 'dideoxy': [1678], 'method': [1679], 'Sequenase': [1681], '2.0': [1682], '(U.S.': [1683], 'Biochemical': [1684], 'Corp.)': [1685, 2042], 'per': [1687, 2019], "manufacturer's": [1689], 'protocol.': [1690, 2022], 'Nucleotide': [1691], 'peptide': [1693, 3206, 4080, 4216], 'were': [1695, 1713, 1807, 1827, 1856, 1942, 1991, 2025, 2050, 2059, 2091, 2108, 2123, 2129, 2142, 2150, 2162, 2193, 2282, 2350, 2370, 2391, 2421, 2516, 2540, 2559, 2685, 2732, 3087, 4248, 4274], 'analyzed': [1696, 3875], 'Wisconsin': [1699], 'software': [1700], 'package': [1701], '(version': [1702], '8.1,': [1703], 'Genetics': [1704], 'Computer': [1705], 'Group,': [1706], 'Inc.).': [1707], 'Multiple': [1708], 'alignments': [1709], 'generated': [1714], 'progressive': [1717], 'pairwise': [1718], 'algorithm': [1719, 1750], '(26Jin': [1720], 'Nei': [1722], 'Mol.': [1724, 2584], 'Evol.': [1726], '1990;': [1727], '7:': [1728], '82-102PubMed': [1729], 'Phylogenetic': [1732], 'analysis': [1733, 2723], 'matrix': [1738], 'evolutionary': [1740], 'distances,': [1741], 'phylogeny': [1744], 'reconstructed': [1746], 'UPGMA': [1749], '(27Felsenstein': [1751], 'Methods': [1753], 'Enzymol.': [1754], '266:': [1756], '418-427Crossref': [1757], 'Yeast': [1761, 2486], 'screening': [1763], 'performed': [1765, 1828, 2163, 2422, 2517, 2560, 2733, 3784, 4196], 'strain': [1768], 'CG-1945': [1769, 1779, 1820], 'according': [1770], 'Two-hybrid': [1774], 'System': [1775], '2': [1776, 1859, 1913, 2085, 2219], 'protocol': [1777], '(CLONTECH).': [1778], 'transformed': [1781], 'bait': [1783], 'plasmid': [1784, 1801, 2308, 2356], '(pAS2–1/Pag)': [1785], 'then': [1787, 2283], 'screened': [1788], 'cell': [1794, 1908, 2201, 3872, 3901, 4104], 'line': [1795], 'constructed': [1799, 3111], 'pGADGH': [1802], '(HL4000A1;': [1803], 'CLONTECH).': [1804], 'Positive': [1805], 'clones': [1806, 3099], 'selected': [1808], 'His3p': [1812], 'β-galactosidase.': [1814], 'Plasmid': [1815], 'DNA': [1816], 'recovered': [1818], 'electroporated': [1822], 'intoEscherichia': [1823], 'coli.': [1824, 1984], 'Reporter': [1825, 2607, 2671], 'assays': [1826, 3786], 'previously': [1831, 2520, 2563, 2735, 3830], '(28Jin': [1832, 2495, 2521], 'D.-Y.': [1833, 2496, 2522], 'Jeang': [1834, 2497, 2523, 2739], 'K.-T.': [1835, 2498, 2524, 2740], 'Nucleic': [1836, 2499, 2525, 3210], 'Acids': [1837, 2500, 2526, 3211], 'Res.': [1838, 2501, 2527, 3212, 3773], '1997;': [1839, 2502, 2528], '25:': [1840, 2503, 2529], '378-387Crossref': [1841, 2504, 2530], '(66)': [1843, 2506, 2532], 'Monolayer': [1846, 2056], 'HepG2': [1849], '100-mm': [1853], 'Petri': [1854], 'disk': [1855], 'harvested': [1857, 2194], 'ml': [1860, 1906], 'immunoprecipitation': [1862, 1950], 'buffer': [1863, 1958, 2210], '(PBS,': [1864], '1%': [1865], 'Nonidet': [1866, 2261], 'P-40,': [1867], '0.5%': [1868], 'deoxycholate,': [1869], '0.1%': [1870], 'SDS,': [1871, 1964], '1': [1872, 1875, 1878, 1881, 1887, 1920, 2066, 2133, 2188, 2228, 2231, 2234, 2237, 2243, 3067, 3329, 3465, 3532, 4083], 'μg/ml': [1873, 1876, 1879, 1888, 2229, 2232, 2235, 2244], 'antipain,': [1874, 2230], 'leupeptin,': [1877, 2233], 'pepstatin,': [1880, 2236], 'mg/ml': [1882, 2238], 'aminoethyl': [1883, 2239], 'benzenesulfonyl': [1884, 2240], 'fluoride,': [1885, 2241], 'aprotinin)': [1889, 2245], 'disrupted': [1891], 'repeated': [1893], 'aspiration': [1894], '21-gauge': [1897], 'needle.': [1898], 'Cell': [1899, 4294], 'debris': [1900], 'removed': [1902, 2143], 'centrifugation.': [1904], 'extract': [1909], 'incubated': [1911, 2131, 2248], 'μg': [1914], 'mouse': [1916], 'monoclonal': [1917], 'antibody': [1918, 4118, 4208], 'h': [1921, 2134], 'at': [1922, 1938, 2100, 2135, 2278, 2286, 3148, 3160, 3196, 3226, 3993], '4': [1923, 1939, 2279, 4133], '°C.': [1924, 1940, 2280], '20': [1925], 'μl': [1926, 2207, 2258], 'G-agarose': [1929], 'added,': [1931, 2269], 'mixture': [1934, 2272], 'rotated': [1936], 'overnight': [1937, 2061], 'Immunoprecipitates': [1941], 'collected': [1943], 'centrifugation,': [1945], 'washed': [1946, 2092, 2196], 'times': [1948], 'buffer,': [1951, 2031], 'resuspended': [1953, 2204], 'SDS': [1955, 2028], 'loading': [1957, 2030], '(60': [1959], 'mm': [1960, 2086, 2212, 2217, 2220, 2223, 2226], 'Tris': [1961], 'base,': [1962], '2%': [1963], '10%': [1965, 2081, 2260], 'glycerol,': [1966], '5%': [1967], '2-mercaptoethanol).': [1968], 'Rabbit': [1969], 'antiserum': [1971, 4071], '(α-Pag)': [1972], 'raised': [1974, 4069], 'against': [1975], 'full-length': [1977, 2319, 3108, 3575], 'recombinant': [1978, 3809, 4095], 'produced': [1981], 'E.': [1983, 2305, 2353], 'Human': [1985], 'multiple': [1986], 'tissue': [1987, 2072, 2114], 'Northern': [1988, 3877, 3974], 'blots': [1989], '(CLONTECH)': [1990], 'probed': [1992, 4001], 'individually': [1993, 2610], '850-bp': [1996], '32P-labeled': [1997], 'BamHI-XhoI': [1998], 'fragment': [1999, 2006], '900-bp': [2004], 'EcoRI-XhoI': [2005], 'Pag,': [2009, 3548], '2-kilobase': [2012], 'pair': [2013, 3166, 3888], 'β-actin': [2015], 'probe': [2017], 'CLONTECH': [2021], 'Protein': [2023], 'samples': [2024], 'solubilized': [2026], 'separated': [2032, 4275], '12%': [2034], 'SDS-PAGE,': [2035], 'electroblotted': [2037], 'onto': [2038, 2125], 'Immobilon-P': [2039], 'membranes': [2040], '(Millipore': [2041], 'semidry': [2045], 'blotter': [2046], '(MilliBlot-SDE,': [2047], 'Millipore).': [2048], 'Blots': [2049], 'visualized': [2051], 'chemiluminescence': [2053], '(Western-Light,': [2054], 'Tropix).': [2055], 'grown': [2060], '18-mm': [2063], 'diameter': [2064], 'glass': [2067], 'coverslips': [2068, 2119], '60': [2070], 'mm-diameter': [2071], 'culture': [2073, 2115], 'dishes': [2074], "Dulbecco's": [2076], 'modified': [2077], "Eagle's": [2078], 'medium': [2079], 'containing': [2080, 2673], 'fetal': [2082], 'calf': [2083], 'serum,': [2084], 'glutamine,': [2087], 'antibiotics.': [2089], 'Cells': [2090, 2281], 'PBS': [2094], 'fixed': [2096, 2121], '10': [2098, 2216, 2276], 'min': [2099, 2253, 2277], '−20': [2101], '°C': [2102], 'absolute': [2104], 'methanol.': [2105], 'Diluted': [2106], 'antibodies': [2107, 2141, 2167, 2179], 'added': [2109], '60-μl': [2111], 'volumes': [2112], 'dishes,': [2116], 'inverted': [2124], 'antibodies.': [2127], 'Antibodies': [2128], 'typically': [2130], 'room': [2136], 'temperature.': [2137], 'Fixative': [2138], 'excess': [2140, 4213], 'several': [2145], 'washes': [2146], 'PBS.': [2148, 2199], 'Coverslips': [2149], 'mounted': [2151], 'slides': [2153], 'Fluormount': [2155], '(Virotech': [2156], 'International).': [2157], 'Double': [2158], 'label': [2159], 'immunofluorescence': [2160], 'experiments': [2161], 'primary': [2166], 'animal': [2172], '(rabbit': [2173], 'mouse)': [2175], 'species-specific': [2177], 'secondary': [2178], 'conjugated': [2180], 'fluorophores': [2183], '(fluorescein': [2184], 'Texas': [2186], 'Red).': [2187], '×': [2189, 3068], '107': [2190], 'twice': [2197], 'pellet': [2202], '400': [2206], 'extraction': [2209], '(10': [2211], 'Hepes,': [2213], 'pH': [2214], '7.5,': [2215], 'KCl,': [2218], 'MgCl2,': [2221], '0.1': [2222], 'EDTA,': [2224], '0.5': [2225], 'dithiothreitol,': [2227], 'ice': [2250], '15': [2252], 'swell': [2255], 'cells.': [2256, 4256], '25': [2257], 'P-40': [2262], '(or': [2263], 'IGEPAL': [2264], 'CA-630': [2265], 'Sigma)': [2267], 'vortexed': [2274], 'spun': [2284], 'briefly': [2285], 'top': [2287, 4023], 'speed': [2288], 'separate': [2290], 'cytosolic': [2292], '(supernatant)': [2293], '(pellet)': [2297], 'fractions.': [2298], 'GST-AOE372': [2299, 4096], 'fusion': [2300, 2329, 4097], 'expressed': [2303, 2351, 3896, 4048], 'coli': [2306, 2354, 3578], 'pGEX-4T-3': [2309], '(Pharmacia': [2310], 'Biotech': [2311], 'Inc.)': [2312], 'insert': [2315], 'coding': [2316], 'mature': [2320, 2345], 'indicated': [2324], 'Fig.': [2326, 3328, 3595, 4021, 4027, 4082, 4132, 4257], '1.': [2327], 'GlutathioneS-transferase': [2328], 'purified': [2332, 2371, 3580], 'Sepharose': [2335], '4B': [2336], 'affinity': [2337], 'columns': [2338], "Pharmacia's": [2340], 'procedures.': [2341], 'form': [2346], 'native': [2348, 4102], 'pKK223–3': [2357], '(Pharmacia)': [2358], 'pag': [2361, 4007, 4015], 'insert.': [2364], 'Recombinant': [2365], 'ammonium': [2373], 'sulfate': [2374], 'fractionation': [2375], '(40–60%': [2376], 'saturation)': [2377], 'sequential': [2379], 'HPLC': [2380], 'DEAE-Sephacel': [2382], 'ion': [2383], 'exchange': [2384], 'TSK': [2386], 'heparin-5PW': [2387], 'columns.': [2388], 'Target': [2389], 'followed': [2392], 'glutamine': [2394, 2402, 3625, 3788], 'synthetase': [2395, 2403, 3626, 3789], 'protection': [2396, 2404, 3623, 3683, 3790], 'assay': [2397, 2420, 2515, 2558, 2731, 2995], 'immunoblotting.': [2400], 'assay,': [2405, 2408], 'indirect': [2406], 'vivo': [2411], 'oxidant': [2412], 'dichloride': [2415], 't-butyl': [2417], 'hydroperoxide)': [2418], 'resistance': [2419], 'essentially': [2423], '29Kim': [2444, 3660], 'I.H.': [2447, 3663, 3768], 'Lee': [2448, 3664], 'K.-Y.': [2449, 3665], 'Stadtman': [2452, 3423, 3668, 3717], 'E.R.': [2453, 3424, 3669, 3718], '1988;': [2457, 3673], '263:': [2458, 3674], '4704-4711Abstract': [2459, 3675], '30Chae': [2466], '16815-16821Abstract': [2479, 3267], 'cultivation': [2487], 'transformation': [2490], 'Probe': [2509], 'labeling': [2510], 'mobility': [2513], 'shift': [2514], 'Two': [2535], 'oligonucleotides': [2536], '5′-AGCTTGGGGAATCTCCGGATCCGGGGAATCTCCA-3′': [2537, 2701], '5′-AGCTTGGAGATTCCCCGGATCCGGAGATTCCCCA-3′': [2539], 'consensus': [2545, 3458], 'κB': [2546], 'site': [2547], 'probe.': [2548], 'Calcium': [2549], 'phosphate': [2550], 'transfection': [2551], 'CAT': [2557], '(31Graham': [2564], 'F.L.': [2565], 'Van': [2566], 'der': [2567], 'Eb': [2568], 'A.J.': [2569], 'Virology.': [2570], '1973;': [2571], '52:': [2572], '457-467Crossref': [2573], '(6499)': [2575], '32Gorman': [2578], 'C.M.': [2579], 'Moffat': [2580], 'L.F.': [2581], 'Howard': [2582], 'B.H.': [2583], '1982;': [2587], '2:': [2588], '1044-1051Crossref': [2589], '(5292)': [2592], 'Radioactivity': [2595], 'TLC': [2597], 'plates': [2598], 'quantitated': [2600], 'Fuji': [2603], 'BAS2000': [2604], 'phosphor': [2605], 'imager.': [2606], 'plasmids': [2608, 2672], 'driven': [2609], 'HTLV-1': [2612, 2682, 2713], 'LTR': [2613, 2616], 'HIV-1': [2615], '(pU3RCAT': [2617], 'pBENNCAT)': [2619], 'elsewhere': [2623], '(33Sodroski': [2624], 'Rosen': [2626], 'C.A.': [2627], 'Haseltine': [2628], 'Science.': [2630], '1984;': [2631], '225:': [2632], '381-384Crossref': [2633], '(487)': [2636], 'Scholar,34Gendelman': [2638], 'H.E.': [2639], 'Phelps': [2640], 'Feigenbaum': [2642], 'Ostrove': [2644], 'J.M': [2645], 'Adashi': [2646], 'Howley': [2648], 'P.M.': [2649], 'Khoury': [2650], 'Ginsberg': [2652], 'H.S.': [2653], 'Martin': [2654], 'M.A.': [2655], '1986;': [2663, 3135, 3213], '83:': [2664], '9759-9763Crossref': [2665], '(275)': [2668], 'synthetic': [2674, 4087], 'motif,': [2676, 2678, 2700, 2705, 2715], 'Sp1': [2677, 2704], '21-bp': [2683, 2714], 'motif': [2684], 'pCAT-Basic': [2688], '(Promega).': [2689], 'Oligonucleotides': [2690], 'motifs': [2695, 3185, 3337, 3355], 'follows:': [2698], '5′-AGCTTGGAGATTCCCCGGATCCGGAGATTCCCCA-3′;': [2703], '5′-AGCTTGGGGAGTGGCGGATCCGGGGAGTGGCA-3′': [2706], '5′-AGCTTGCCACTCCCCGGATCCGCCACTCCCCA-3′;': [2708], '5′-AGCTACCATATTAGGATCCATATTAGGT-3′': [2710], '5′-AGCTACCTAATATGGATCCTAATATGGT-3′;': [2712], '5′-AGCTTAGGCCCTGACGTGTCCCCCTGGATCCTAGGCCCTGACGTGTCCCCCTA-3′': [2716], '5′-AGCTTAGGGGGACACGTCAGGGCCTAGGATCCAGGGGGACACGTCAGGGCCTA-3′.': [2718], 'HIV': [2719], 'infection,': [2720], 'Western': [2721, 4127], 'blot': [2722], 'viral': [2725], 'p24,': [2727], 'reverse': [2729], 'transcriptase': [2730], '(35Huang': [2737], 'L.-M.': [2738], 'Virol.': [2742], '67:': [2744], '6937-6944Crossref': [2745], 'Peroxiredoxins': [2749], 'mouse,': [2759], 'rat,': [2760], 'bovine': [2762], 'emerging': [2941], 'various': [2946], 'aspects': [2947], '(2Sen': [2951], 'prompted': [2965], 'us': [2966], 'investigate': [2968], 'function(s)': [2970], 'peroxiredoxins.': [2973, 4064], 'An': [2974, 3314], 'initial': [2975], 'approach': [2976], 'employing': [2977], 'degenerate': [2978], 'polymerase': [2979], 'reaction': [2981, 3822], 'attempted': [2983], 'but': [2984], 'found': [2985, 3159, 3338, 3459, 4010, 4185], 'unsuccessful.': [2988], 'Subsequently,': [2989], '(36Fields': [2996], 'O.': [2999], 'Nature.': [3000], '340:': [3002], '245-246Crossref': [3003], '(4880)': [3006], 'From': [3066], '109': [3069], 'individual': [3070], 'transformants': [3071], 'library,': [3076], 'six': [3079, 3086], 'interactive': [3080], 'clones.': [3081], 'Interestingly,': [3082], 'two': [3083, 3335, 3785], 'derivatives': [3088], 'ofpag,': [3089], 'indicating': [3090], 'homodimerize.': [3095], 'four': [3098, 3321], 'all': [3100, 3340, 3898], 'contained': [3101], 'portions': [3102], 'cDNA.': [3106], '(clone': [3112], '372)': [3113], '5′-sequence': [3116], 'repaired': [3117], '5′-rapid': [3119], 'ends.': [3123], 'intact': [3126], 'cDNA,': [3127], 'Kozak': [3129], '(GTGGTCATGG)': [3131], '(37Kozak': [3132], '44:': [3136], '283-292Abstract': [3137], '(3599)': [3143], 'present': [3147], 'frame': [3151], 'initiation': [3152], 'codon,': [3153], 'poly(A)': [3156], 'tail': [3157], '3′-end': [3162], '0.95-kilobase': [3165], '(Fig.': [3168, 3464, 3531, 3928, 3968, 4054, 4109, 4154, 4190, 4201, 4217, 4241], '1).': [3169], 'novel': [3173], '271-amino': [3174], '(apparent': [3177], 'molecular': [3178], 'mass': [3179], '31': [3181], 'kDa)': [3182, 4100, 4108], 'consistent': [3186, 4149, 4234], 'distinctly': [3193, 4019, 4276], 'hydrophobic': [3194], 'region': [3195], 'N': [3198], 'terminus,': [3199], 'compatible': [3202], '(38von': [3207], 'Heijne': [3208], '4683-4690Crossref': [3215], '(3693)': [3218], 'cleavage': [3224], 'sites': [3225], 'Ser77': [3228], 'Lys78': [3230], 'Ala79': [3232], 'Lys80.': [3234], '40–85%': [3241], 'homology': [3242], 'peroxiredoxins': [3245, 3324, 3342, 3463, 3525, 3988], '(70%': [3250], 'identity,': [3251, 3284], '82%': [3252], 'similarity)': [3253, 3286], '(30Chae': [3254], 'AhpC': [3276], '(alkyl': [3277], 'hydroperoxide': [3278], '22-kDa': [3280], 'component;': [3282], '51%': [3283], '67%': [3285], '(25Chae': [3287, 3633], 'presented': [3326], 'Notably,': [3331], 'conserves': [3333], 'cysteine-containing': [3345], 'segments': [3346], 'surrounding': [3347], 'Cys47': [3348], '(FFYPLDFTFVCPTEI)': [3349], 'Cys168': [3351], '(HGEVCPA)).': [3352], 'These': [3353, 3853], 'cysteine': [3354], 'being': [3360], 'catalysis': [3363], 'peroxides': [3365], 'Scholar,39Poole': [3404], '35:': [3408], '65-75Crossref': [3409], '(108)': [3412], '40Netto': [3415, 3709], 'L.E.S.': [3416, 3710], 'Chae': [3417, 3711], 'Kang': [3419, 3713], 'S.-W.': [3420, 3714], '271:': [3429, 3723], '15315-15321Abstract': [3430, 3724], '(204)': [3438, 3732], 'time,': [3444], '(e.g.Thr67,': [3449], 'Arg106,': [3450], 'Tyr114,': [3451], 'Lys186,': [3452], 'Leu187,': [3453], 'Lys188)': [3455], 'differ': [3456], 'B).': [3466, 3807, 3972, 4157], 'Because': [3467, 4158], 'peroxiredoxin': [3468, 3543, 3557, 3619], 'subfamilies': [3469], 'diverge': [3470], 'approximately': [3474], '5–10%': [3475], '(21Chae': [3476], 'Scholar),': [3519], 'phylogenetically': [3521], 'segregates': [3522], 'into': [3526], 'branch': [3530], 'C).': [3533, 3930], '(A': [3534], 'IV.': [3544], 'By': [3545, 3973], 'convention,': [3547], 'antioxidant/Tpx,': [3550], 'MER5': [3552], 'prototypes': [3554], 'I,': [3558], 'II,': [3559], 'III': [3561], 'subfamilies,': [3562], 'respectively.)2': [3563], 'wished': [3565], 'assess': [3567, 4120], 'AOE372.': [3572, 3616, 4182], 'overexpressed': [3574], 'inE.': [3577], 'stainable': [3583], 'single': [3584, 3604], 'polypeptide': [3585], 'homogeneity.': [3586], 'Purified': [3587], 'assessed': [3590], 'SDS-PAGE': [3593], '6': [3596], 'A)': [3597], 'verified': [3600, 4221, 4249], 'band.': [3606], 'preparation,': [3609], 'assayed': [3611], 'potential': [3614], 'inactivation': [3628], 'thiol-dependent': [3630], 'metal-catalyzed': [3631], 'conferred': [3685], 'serves': [3737], 'bioactive': [3740], 'donor': [3742], '41Kwon': [3761], 'Park': [3763], 'J.W.': [3764], 'Choi': [3765], 'W.K.': [3766], 'Commun.': [3774], '201:': [3776], '8-15Crossref': [3777], '(100)': [3780], 'thioredoxin-linked': [3793], 'activity.': [3796], 'assays,': [3799], 'active': [3803], '(Fig.2,': [3804], 'Accordingly,': [3808], 'scavenged': [3811], 'H2O2in': [3812], 'presence': [3814], 'thioredoxin,': [3816], 'reductase,': [3818], 'kinetics': [3823], 'potency': [3825], 'virtually': [3826], 'identical': [3827], 'biochemically': [3855, 4250], 'functional': [3860], 'Expression': [3864], 'mRNA': [3867, 3893, 3977, 4152], 'tissues': [3870, 4050], 'blotting.': [3878, 4128], 'transcript': [3880], 'apparent': [3883], 'size': [3884], '1.0': [3886], 'kilobase': [3887], '(Fig.3,': [3889], 'upper': [3890], 'panel).': [3891], 'ubiquitously': [3895], 'tested': [3899], 'promyelocytic': [3904], 'leukemia': [3905, 3911, 3914], 'HL60,': [3906], 'S3,': [3908], 'chronic': [3909], 'myelogenous': [3910], 'K562,': [3912], 'lymphoblastic': [3913], 'MOLT-4,': [3915], "Burkitt's": [3916], 'lymphoma': [3917], 'Raji,': [3918], 'colorectal': [3919], 'adenocarcinoma': [3920], 'SW480,': [3921], 'lung': [3922], 'carcinoma': [3923], 'A549,': [3924], 'melanoma': [3926], 'G361': [3927], '3': [3929], 'levels': [3934], 'vary': [3935], 'significantly': [3936], 'tissues,': [3939], 'pancreas': [3941, 4053], '>': [3942, 3944, 3953, 3955, 3961, 4139, 4141, 4143], 'liver': [3943, 4140], 'heart,': [3945], '(skeletal)': [3946], 'muscle,': [3947], 'colon': [3948], '(mucosal': [3949], 'lining)': [3950], 'testis': [3952], 'ovary': [3954], 'placenta,': [3956], 'lung,': [3957], 'kidney,': [3958], 'prostate': [3960], '(small)': [3962], 'intestine,': [3963], 'thymus,': [3964, 4041], 'spleen,': [3965, 4040], 'brain': [3967], '3,': [3969, 4022, 4155], 'blotting,': [3975], 'detected': [3980], 'peripheral': [3982], 'blood': [3983], 'leukocytes.': [3984], 'check': [3986], 'could': [3989], 'differentially': [3991], 'level': [3995], 'tissue-specific': [3997], 'expression,': [3998], 'profile': [4005], 'mRNA.': [4008], 'patterns': [4017, 4137], 'contrasted': [4018], '(compare': [4020], 'panels,': [4024, 4029], 'AOE372;': [4025], '3,middle': [4028], 'pag).': [4030], 'blots,': [4034], 'whereaspag': [4035], 'preferentially': [4037], 'abundant': [4038], 'brain,': [4043], '3).': [4055], 'there': [4057], 'tissue-distinct': [4059], 'profiles': [4061, 4153], 'rabbit': [4070], '(372-1)': [4072], 'keyhole': [4075], 'limpet': [4076], 'hemocyanin-conjugated': [4077], 'C-terminal': [4078], '(see': [4081], 'peptide).': [4088], 'Antibody': [4089], '372-1': [4090, 4207], 'reacts': [4091], '(55': [4099], '(23': [4107], '4,A': [4110], 'B,': [4112], 'lane': [4113], '2).': [4114, 4193], 'As': [4129], 'shown': [4130], 'C,': [4134], '(pancreas': [4138], 'heart': [4142], 'spleen': [4144], 'thymus)': [4146], 'generally': [4148], 'Aand': [4156], 'location': [4160], 'inside': [4164], 'provide': [4167], 'information': [4169], 'function,': [4171], 'stained': [4173, 4226], 'determine': [4177], 'subcellular': [4179], 'locale(s)': [4180], 'predominantly': [4186], '5': [4191, 4202, 4218, 4242, 4258], 'A,panel': [4192, 4219], 'Control': [4194], 'stainings': [4195], 'preimmune': [4199], 'A,': [4203, 4243], 'panel': [4204, 4244], '1)': [4205], 'first': [4209], 'neutralized': [4210], 'immunizing': [4215], '3)': [4220], 'specificity': [4223], 'signals.': [4227], 'staining': [4230], 'similar': [4237], 'compartmentalization': [4238], '4).': [4245], 'immunostainings': [4247], 'parallel': [4252], 'detergent': [4253], 'fractionations': [4254], 'B': [4259], 'shows': [4260], 'co-fractionated': [4265], 'β-tubulin': [4267], '(a': [4268], 'protein)': [4272], 'NuMA': [4278], '(nuclear/mitotic': [4279], 'apparatus': [4280], 'marker)': [4286], '(42Compton': [4287], 'D.A.': [4288], 'Szilak': [4289], 'Cleveland': [4291], 'D.W.': [4292], '116:': [4297], '1395-1408Crossref': [4298]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2059129711', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 12}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 13}, {'year': 2014, 'cited_by_count': 13}, {'year': 2013, 'cited_by_count': 13}, {'year': 2012, 'cited_by_count': 11}], 'updated_date': '2024-12-13T08:24:42.596085', 'created_date': '2016-06-24'}