Publication Information

{'id': 'https://openalex.org/W2059068497', 'doi': 'https://doi.org/10.1001/jama.1976.03270200046031', 'title': 'Neurosyphilis and Penicillin Levels in Cerebrospinal Fluid', 'display_name': 'Neurosyphilis and Penicillin Levels in Cerebrospinal Fluid', 'publication_year': 1976, 'publication_date': '1976-11-08', 'ids': {'openalex': 'https://openalex.org/W2059068497', 'doi': 'https://doi.org/10.1001/jama.1976.03270200046031', 'mag': '2059068497', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/989815'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/jama.1976.03270200046031', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S172573765', 'display_name': 'JAMA', 'issn_l': '0098-7484', 'issn': ['0098-7484', '1538-3598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025298181', 'display_name': 'John A. Mohr', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'John A. Mohr', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5025298181'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.47, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 169, 'citation_normalized_percentile': {'value': 0.993022, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '236', 'issue': '19', 'first_page': '2208', 'last_page': '2208'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11934', 'display_name': 'Syphilis Diagnosis and Treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11934', 'display_name': 'Syphilis Diagnosis and Treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10428', 'display_name': 'Reproductive tract infections research', 'score': 0.992, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11660', 'display_name': 'Blood groups and transfusion', 'score': 0.9818, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pleocytosis', 'display_name': 'Pleocytosis', 'score': 0.8055778}, {'id': 'https://openalex.org/keywords/neurosyphilis', 'display_name': 'Neurosyphilis', 'score': 0.7653766}, {'id': 'https://openalex.org/keywords/intramuscular-injection', 'display_name': 'Intramuscular injection', 'score': 0.60717237}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9662062}, {'id': 'https://openalex.org/C174802600', 'wikidata': 'https://www.wikidata.org/wiki/Q12190', 'display_name': 'Penicillin', 'level': 3, 'score': 0.9154719}, {'id': 'https://openalex.org/C2777483564', 'wikidata': 'https://www.wikidata.org/wiki/Q749881', 'display_name': 'Pleocytosis', 'level': 3, 'score': 0.8055778}, {'id': 'https://openalex.org/C2781319584', 'wikidata': 'https://www.wikidata.org/wiki/Q7888578', 'display_name': 'Neurosyphilis', 'level': 4, 'score': 0.7653766}, {'id': 'https://openalex.org/C2779651940', 'wikidata': 'https://www.wikidata.org/wiki/Q54196', 'display_name': 'Cerebrospinal fluid', 'level': 2, 'score': 0.733106}, {'id': 'https://openalex.org/C2776291583', 'wikidata': 'https://www.wikidata.org/wiki/Q432083', 'display_name': 'Intramuscular injection', 'level': 2, 'score': 0.60717237}, {'id': 'https://openalex.org/C2776983459', 'wikidata': 'https://www.wikidata.org/wiki/Q41083', 'display_name': 'Syphilis', 'level': 3, 'score': 0.5488676}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.4538057}, {'id': 'https://openalex.org/C2781026528', 'wikidata': 'https://www.wikidata.org/wiki/Q48143', 'display_name': 'Meningitis', 'level': 2, 'score': 0.44306406}, {'id': 'https://openalex.org/C2779828710', 'wikidata': 'https://www.wikidata.org/wiki/Q423741', 'display_name': 'Procaine', 'level': 2, 'score': 0.4293018}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34390813}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.34106773}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.32309428}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.12856352}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.07470721}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D009494', 'descriptor_name': 'Neurosyphilis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D010400', 'descriptor_name': 'Penicillin G', 'qualifier_ui': 'Q000134', 'qualifier_name': 'cerebrospinal fluid', 'is_major_topic': True}, {'descriptor_ui': 'D002555', 'descriptor_name': 'Cerebrospinal Fluid', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D002555', 'descriptor_name': 'Cerebrospinal Fluid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007273', 'descriptor_name': 'Injections, Intramuscular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007275', 'descriptor_name': 'Injections, Intravenous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008214', 'descriptor_name': 'Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009494', 'descriptor_name': 'Neurosyphilis', 'qualifier_ui': 'Q000134', 'qualifier_name': 'cerebrospinal fluid', 'is_major_topic': False}, {'descriptor_ui': 'D009494', 'descriptor_name': 'Neurosyphilis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010400', 'descriptor_name': 'Penicillin G', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D010400', 'descriptor_name': 'Penicillin G', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D010400', 'descriptor_name': 'Penicillin G', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/jama.1976.03270200046031', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S172573765', 'display_name': 'JAMA', 'issn_l': '0098-7484', 'issn': ['0098-7484', '1538-3598'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/989815', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 12, 'referenced_works': ['https://openalex.org/W1999564203', 'https://openalex.org/W2012367340', 'https://openalex.org/W2023619098', 'https://openalex.org/W2044656416', 'https://openalex.org/W2058346936', 'https://openalex.org/W2075551512', 'https://openalex.org/W2094066755', 'https://openalex.org/W2119151330', 'https://openalex.org/W2339925772', 'https://openalex.org/W2344770554', 'https://openalex.org/W2409700289', 'https://openalex.org/W56744347'], 'related_works': ['https://openalex.org/W88550938', 'https://openalex.org/W810545828', 'https://openalex.org/W4220771317', 'https://openalex.org/W2968974283', 'https://openalex.org/W2947123155', 'https://openalex.org/W2444471620', 'https://openalex.org/W2417106868', 'https://openalex.org/W2416192898', 'https://openalex.org/W2411753238', 'https://openalex.org/W2315065641'], 'abstract_inverted_index': {'Because': [0], 'neurosyphilis': [1], 'may': [2], 'progress': [3], 'despite': [4], 'therapy': [5], 'with': [6, 13], 'the': [7, 19, 95, 102, 118, 127], 'recommended': [8], 'penicillin': [9, 36, 51, 68, 88, 100, 111, 116, 125], 'regimens,': [10], '15': [11], 'subjects': [12], 'positive': [14], 'tests': [15], 'for': [16], 'syphilis': [17], 'in': [18, 101, 117, 126], 'serum': [20], 'and': [21, 39, 47, 65, 94], 'cerebrospinal': [22], 'fluid': [23], '(CSF)': [24], 'were': [25, 80], 'studied.': [26], 'All': [27], 'of': [28, 105], 'these': [29], 'patients': [30, 84, 107], 'had': [31, 91, 97, 113, 122], 'CSF': [32], 'pleocytosis.': [33], 'Two': [34], 'received': [35, 49, 86, 109], 'G': [37, 112], '(5': [38], '10': [40], 'million': [41, 54], 'units': [42, 55], 'per': [43, 56], 'day': [44], 'intravenously,': [45], 'respectively)': [46], '13': [48, 106], 'benzathine': [50, 110], 'G,': [52, 89], '3.6': [53], 'week': [57], 'intramuscularly;': [58], 'treatment': [59], 'lasted': [60], 'four': [61], 'weeks.': [62], 'During': [63], 'intravenous': [64, 87], 'after': [66], 'intramuscular': [67], 'therapy,': [69], 'a': [70], 'spinal': [71], 'tap': [72], 'was': [73], 'performed': [74], 'on': [75], 'all': [76], 'subjects;': [77], 'later,': [78], 'assays': [79], 'done.': [81], 'Of': [82], 'two': [83], 'who': [85, 108], 'one': [90, 120], '0.3': [92], 'mug/ml': [93, 99, 124], 'other': [96], '2.4': [98], 'CSF.': [103, 128], 'Twelve': [104], 'no': [114], 'detectable': [115], 'CSF;': [119], 'patient': [121], '0.1': [123]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2059068497', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2025-01-07T09:19:02.382620', 'created_date': '2016-06-24'}