Title: Two novel polycyclic spiro lignans from Gymnotheca involucrata
Abstract: Two novel lignans, gymnothespirolignans A (1) and B (2), possessing a rare polycyclic spiro skeleton, were isolated from the endemic plant of Gymnotheca involucrata Pei. Their structures were determined by spectroscopic evidences and the absolute configurations were confirmed by single crystal X-ray diffraction analysis. Compounds 1 and 2 showed promising antiviral activities against RSV with an IC50 value of 31.87 and 17.51 mu M, respectively. (C) 2014 Elsevier Ltd. All rights reserved.
Publication Year: 2014
Publication Date: 2014-10-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 14
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