Publication Information

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1483, 1602, 1621, 1735, 1885, 2019, 2089, 2154, 2216, 2280, 2385, 2394, 2939, 3062, 3400, 4397, 4455, 4842, 5290, 5441], 'an': [21, 221, 477, 819, 991, 2039, 2466, 2473, 2569, 2641, 2952, 3134, 3165, 3452, 3627, 4376, 4456, 4843, 5442], 'intermediate.': [22, 222], 'The': [23, 52, 66, 111, 223, 252, 266, 311, 797, 979, 1298, 1335, 1514, 1827, 2022, 2049, 2092, 2156, 2185, 2237, 2403, 2452, 2479, 2531, 2557, 2611, 2817, 3037, 3123, 3144, 3191, 3681, 3795, 4234, 4275, 4340, 4729, 4859, 4929, 5183], 'regulatory': [24, 224, 1092, 5002], 'role': [25, 225, 661, 3581], 'of': [26, 119, 139, 146, 226, 319, 339, 346, 424, 432, 437, 448, 465, 482, 485, 508, 600, 630, 665, 815, 958, 981, 994, 1005, 1015, 1100, 1145, 1215, 1219, 1234, 1242, 1247, 1410, 1432, 1443, 1516, 1524, 1532, 1614, 1656, 1727, 1740, 1763, 1767, 1804, 1817, 1824, 1840, 1852, 1867, 1882, 1907, 1922, 1976, 1996, 2025, 2053, 2095, 2164, 2183, 2188, 2199, 2242, 2245, 2257, 2269, 2273, 2315, 2343, 2376, 2380, 2388, 2391, 2413, 2427, 2430, 2441, 2454, 2469, 2476, 2481, 2510, 2516, 2551, 2559, 2564, 2604, 2640, 2643, 2651, 2749, 2765, 2789, 2822, 2863, 2868, 2897, 2924, 2998, 3009, 3040, 3114, 3121, 3146, 3200, 3216, 3261, 3264, 3271, 3283, 3323, 3347, 3359, 3387, 3393, 3398, 3411, 3420, 3427, 3435, 3456, 3464, 3499, 3512, 3528, 3531, 3539, 3560, 3564, 3570, 3575, 3582, 3598, 3639, 3677, 3782, 3810, 3864, 3871, 3902, 3920, 3939, 3948, 3955, 3961, 3981, 3989, 3999, 4019, 4043, 4166, 4186, 4226, 4277, 4290, 4312, 4323, 4343, 4348, 4379, 4388, 4394, 4405, 4452, 4463, 4500, 4513, 4537, 4652, 4731, 4744, 4772, 4800, 4853, 4862, 4886, 4931, 4946, 4956, 4972, 5037, 5043, 5081, 5088, 5092, 5103, 5154, 5171, 5206, 5256, 5286, 5303, 5307, 5335, 5353, 5445, 5510, 5617], 'isochorismate': [27, 227, 400, 1222, 1237, 1307, 1384, 2392, 2401, 2656, 3203, 3515, 3640, 3678, 4676, 5555], 'synthase,': [28, 228], 'first': [30, 230, 472, 514, 612, 620, 1217, 1434, 2981, 3562, 3584, 4539], 'enzyme': [31, 40, 68, 231, 240, 268, 473, 518, 647, 1218, 1230, 2381, 2417, 2652, 2871, 3060, 3113, 3485, 3519, 3563, 3585, 4566, 4632, 4872, 5509, 5577], 'in': [32, 48, 73, 123, 126, 131, 144, 151, 232, 248, 273, 323, 326, 331, 344, 351, 462, 580, 597, 616, 649, 662, 676, 787, 941, 1087, 1251, 1349, 1388, 1413, 1521, 1724, 1919, 2123, 2196, 2278, 2311, 2496, 2505, 2518, 2568, 2633, 2637, 2679, 2777, 2906, 3073, 3133, 3300, 3368, 3417, 3424, 3443, 3482, 3520, 3551, 3586, 3610, 3667, 3780, 3972, 3986, 3997, 4016, 4052, 4183, 4252, 4262, 4327, 4354, 4468, 4525, 4559, 4571, 4596, 4622, 4627, 4741, 4769, 4880, 4889, 4907, 4939, 4959, 5009, 5040, 5231, 5341, 5350, 5428, 5550], 'biosynthetic': [35, 174, 235, 374, 408, 582, 652, 679, 829, 960, 1018, 1150, 1446, 4471], 'pathway,': [36, 236, 1078, 3566, 3601], 'was': [37, 55, 69, 237, 255, 269, 1605, 1617, 1789, 1808, 1901, 1914, 1939, 1962, 2027, 2055, 2098, 2175, 2191, 2408, 2460, 2484, 2566, 2589, 2613, 2631, 2658, 2734, 2901, 2928, 2936, 2987, 3017, 3139, 3183, 3197, 3274, 3415, 3437, 3459, 3467, 3487, 3624, 3674, 4260, 4280, 4287, 5451], 'studied.': [38, 238], 'This': [39, 239, 1229, 1436, 1912, 2772, 3016, 3447, 3497, 5235], 'encoded': [42, 242, 4293], 'by': [43, 243, 415, 476, 839, 1003, 1303, 1391, 1424, 1429, 1653, 1810, 1860, 1964, 1993, 2029, 2057, 2100, 2219, 2266, 2336, 2410, 2424, 2436, 2462, 2538, 2615, 2742, 2828, 3019, 3030, 3052, 3195, 3402, 3439, 3626, 3917, 3969, 3994, 4258, 4264, 4283, 4402, 4486, 4564, 4737, 4765, 4856, 4900, 5187, 5239, 5561], 'pchA,': [44, 244, 1243], 'last': [46, 246, 1245, 4621], 'gene': [47, 142, 247, 342, 1246, 1337, 2669, 2676, 4326, 4618], 'pchDCBA': [50, 250, 1020, 1249, 4407], 'operon.': [51, 251], 'PchA': [53, 113, 178, 253, 313, 378, 1807, 1830, 1900, 1961, 2026, 2054, 2097, 2190, 2275, 2512, 2565, 2586, 2706, 2733, 2824, 2870, 2932, 2947, 2986, 3010, 3112, 3124, 3155, 3196, 3201, 3361, 3394, 3441, 3458, 3508, 3982, 4256, 4344, 4357, 4389, 4863, 4898, 5036, 5433], 'protein': [54, 254, 1764, 1948, 2141, 2764, 3673, 3683, 4279, 4295, 4740], 'purified': [56, 256, 1401, 1620, 2274, 2344, 2511, 2735, 3457, 3532], 'to': [57, 134, 257, 334, 670, 673, 784, 811, 1085, 1236, 1407, 1415, 1791, 2060, 2177, 2347, 2415, 2528, 2548, 2649, 2661, 2725, 2736, 3492, 3516, 3542, 3590, 3616, 3957, 4028, 4036, 4040, 4213, 4221, 4315, 4363, 4399, 4474, 4873, 4948, 5168, 5337, 5417, 5453, 5520], 'apparent': [58, 258, 2180, 2737, 3166], 'electrophoretic': [59, 259], 'homogeneity': [60, 260, 2738], 'a': [62, 70, 87, 93, 184, 191, 197, 262, 270, 287, 293, 384, 391, 397, 413, 658, 937, 1603, 1606, 1743, 1792, 1821, 1838, 1879, 1920, 1942, 1973, 2011, 2090, 2217, 2312, 2487, 2634, 2760, 2888, 2907, 2915, 3063, 3174, 3259, 3373, 3552, 3742, 3746, 3852, 3861, 3900, 4253, 4400, 4469, 4568, 4630, 4650, 4810, 5041, 5044, 5104, 5203, 5426, 5562, 5575, 5615], 'PchA-overexpressingP.': [63, 263], 'strain.': [65, 265], 'native': [67, 267, 2096, 2189, 3031, 4614], '52-kDa': [71, 271], 'monomer': [72, 272], 'solution,': [74, 274], 'its': [76, 276, 828, 959, 997, 2463, 3161, 4613, 5415], 'activity': [77, 277, 1214, 2382, 2563, 2630, 2935, 3072, 3151, 3182, 3273, 3358, 3559, 3688, 5439], 'strictly': [78, 278, 1339, 5195], 'depended': [79, 279, 3117], 'on': [80, 280, 1012, 2038, 2104, 2561, 2984, 3001, 3023, 3118, 3984, 4534, 4876, 5202], 'Mg2+.': [81, 281, 3122], 'At': [82, 282], 'pH': [83, 283, 1775, 2322, 2577, 3186], '7.0,': [84, 284, 2323, 2578], 'optimum,': [86, 286], 'Km': [88, 288, 3167], '=': [89, 95, 289, 295, 3168, 3176, 4867], '4.5': [90, 290, 3169, 4868], 'ॖm': [91, 291, 2333, 2493, 2622, 3172, 3422], 'kcat': [94, 294, 3175], '43.1': [96, 296, 3177], 'min−1': [97, 297], 'were': [98, 109, 298, 309, 1651, 1708, 1833, 1858, 1876, 1983, 1991, 2159, 2250, 2264, 2445, 2503, 2546, 2600, 3480, 3614, 3778, 3966, 4010, 4045, 4177, 4228], 'determined': [99, 116, 182, 299, 316, 382, 1422, 1992, 2028, 2485], 'for': [100, 300, 1097, 1440, 1530, 1737, 2167, 2398, 2500, 2594, 3213, 3634, 4062, 4242, 4864, 4969, 5251, 5414, 5424, 5606, 5614], 'chorismate.': [101, 301], 'No': [102, 302], 'feedback': [103, 303, 422, 628, 4482], 'inhibitors': [104, 304], 'or': [105, 305, 434, 1616, 3269, 3297, 3316, 3326, 3345, 3788, 4004, 4171, 4371, 5210], 'other': [106, 306, 4392, 4597, 4884], 'allosteric': [107, 307, 1430], 'effectors': [108, 308, 3263], 'found.': [110, 310], 'intracellular': [112, 312, 795, 4341], 'concentration': [114, 314, 1426, 2249, 3442, 4342, 4358, 4499], 'critically': [115, 315, 4532], 'rate': [118, 318, 1823, 1975, 3463, 3574, 4347, 4910], 'formation': [121, 321, 1420, 2387, 3434, 3588], 'both': [122, 322, 2715, 3214, 3912], 'vitro': [124, 324, 5429], 'vivo.': [127, 327], 'cultures': [129, 329, 3781, 3977], 'grown': [130, 330, 1723, 3381, 4011, 4178], 'iron-limiting': [132, 332], 'media': [133, 333], 'high': [135, 335, 2337, 4860], 'cell': [136, 336, 1706, 2878], 'densities,': [137, 337], 'overexpression': [138, 338, 3605, 3792, 3915, 3971, 3983], 'pchA': [141, 341, 1336, 2668, 3914, 3970, 4617], 'resulted': [143, 343], 'overproduction': [145, 345, 3930], 'well': [149, 349, 429, 1482, 2991], 'enhanced': [152, 352, 3952], 'formation.': [154, 354], 'From': [155, 355, 4332], 'this': [156, 356, 982, 1075, 3388, 3719, 4366, 4565, 4628, 4727, 4732, 4871], 'work': [157, 357], 'earlier': [159, 359], 'studies,': [160, 360], 'it': [161, 361, 1938, 3738], 'proposed': [163, 363], 'that': [164, 364, 1381, 1400, 1418, 2781, 2832, 2946, 3058, 3341, 3506, 3550, 3666, 3727, 4309, 4497, 4849, 4918, 4936, 5048, 5224, 5242, 5301, 5506, 5549], 'one': [165, 365, 607, 645, 4507], 'important': [166, 366, 783], 'factor': [167, 367, 3367], 'influencing': [168, 368], 'flux': [170, 370, 4362], 'through': [171, 371], 'pathway': [175, 375, 439, 487, 3292, 3350, 4396, 4472, 4516, 4855], 'concentration,': [179, 379], 'which': [180, 380, 419, 799, 834, 1010, 1140, 1331, 2713, 3611, 3873, 4625, 5248, 5314], 'at': [183, 383, 592, 1820, 1870, 1972, 1987, 2405, 2591, 2602, 3033, 3185, 4013, 4180, 4809], 'transcriptional': [185, 385, 526, 1007], 'level,': [186, 386], 'with': [187, 387, 996, 1341, 1457, 1731, 1801, 1814, 1848, 1864, 1878, 1903, 1952, 1968, 2126, 2207, 2438, 2491, 2507, 2522, 2647, 2739, 2780, 3127, 3160, 3164, 3202, 3741, 3787, 3867, 3908, 3935, 3974, 4005, 4172, 4882, 5099, 5161, 5198, 5608], 'acting': [189, 389, 4841], 'positive': [192, 392], 'signal': [193, 393, 1076], 'iron': [195, 395, 843, 1134, 3383, 3812, 4314, 4384, 4773, 4837], 'negative': [198, 398], 'signal.': [199, 399], 'synthase': [401, 624, 1223, 5083, 5091, 5438], 'dihydroaeruginoate': [402, 1647, 3298], 'dithiothreitol': [403], 'isopropyl-औ-d-': [404], 'thiogalactopyranoside': [405], 'bacteria,': [407], 'pathways': [409, 583, 4599], 'are': [410, 794, 835, 1386, 2885, 2912, 4845, 5001, 5049, 5249, 5254, 5292, 5315, 5323], 'regulated,': [411], 'rule,': [414], 'their': [416], 'end': [417, 586, 792, 1080, 1408, 3286, 4488], 'products,': [418, 3859], 'can': [420, 1354, 3355], 'cause': [421], 'inhibition': [423, 629, 3268, 4483], 'early': [425], 'key': [426, 646, 4508], 'enzymes': [427, 436, 484, 961, 4393, 4885], 'repression': [431, 957, 4404, 4485], 'some': [433, 2943], 'all': [435, 483, 791, 1395], '(1Madigan': [440], 'M.T.': [441], 'Martinko': [442], 'J.M.': [443], 'Parker': [444], 'J.': [445, 536, 551, 567, 704, 722, 740, 771, 854, 885, 929, 1044, 1064, 1165, 1290, 1315, 1574, 1630, 1673, 1692, 2068, 2288, 2356, 3077, 3101, 3220, 3648, 3702, 3839, 3884, 4197, 4423, 4544, 4668, 4684, 4787, 5137, 5269, 5387, 5529, 5588], 'Brock': [446], 'Biology': [447], 'Microorganisms.': [449], '9th': [450], 'Ed.': [451], 'Prentice-Hall,': [452], 'Inc.,': [453], 'Upper': [454], 'Saddle': [455], 'River,': [456], 'NJ2000:': [457], '212-235Google': [458], 'Scholar).': [459, 504, 574, 780, 869, 978, 1073, 1128, 1208, 1297, 1513, 1598, 1645, 1758, 2236, 2303, 2816, 2977, 3256, 3663, 3717, 3773, 3849, 3895, 4447, 4557, 4594, 4794, 4835, 4993, 5150, 5278, 5406, 5486, 5544, 5601], 'For': [460, 595], 'example,': [461, 820, 4457], 'histidine': [463, 468], 'biosynthesis': [464, 507, 599, 664, 4573], 'Salmonella': [466], 'enterica,': [467], 'allosterically': [469], 'inhibits': [470, 512, 606, 618, 644], 'represses,': [475], 'attenuation': [478], 'mechanism,': [479], 'expression': [481, 1144, 1352, 4272, 4322, 4387, 4799, 4899], '(2Winkler': [488], 'M.E.': [489], 'Escherichia': [490, 3074], 'coli': [491, 3075, 3218, 5447], 'Salmonella,': [493], 'Cellular': [494], 'Molecular': [496], 'Biology.': [497], 'ASM': [498, 5217], 'Press,': [499], 'Washington,': [500], 'D.': [501, 530, 547, 904, 928, 969, 1030, 1063, 1164, 1180, 1265, 1289, 1314, 1368, 1502, 1549, 1573, 1589, 1629, 1672, 1694, 2224, 2287, 2355, 2692, 2805, 2848, 2966, 3647, 3701, 3762, 3821, 4422, 4438, 4667, 4683, 4714, 4753, 4786, 4824, 5066, 5120, 5261, 5475, 5528], 'C.1996:': [502], '485-505Google': [503], 'arginine': [506, 511], 'aeruginosa,': [510, 1102], 'second': [517, 632, 3518, 3693], 'represses': [520], 'sixth': [522], 'enzyme,': [523, 622, 3125, 4504, 4540], 'involving': [524], 'regulator': [527, 1008], 'ArgR': [528], '(3Haas': [529], 'Kurer': [531], 'V.': [532, 926, 1162, 1287, 1571, 1670, 4420, 4665, 4784], 'Leisinger': [533, 548], 'T.': [534, 549, 878, 4978, 5116], 'Eur.': [535, 550], 'Biochem.': [537, 552, 2001, 2228], '1972;': [538], '31:': [539], '290-295Crossref': [540], 'PubMed': [541, 556, 572, 693, 713, 731, 745, 776, 865, 890, 911, 934, 974, 1035, 1049, 1069, 1124, 1170, 1185, 1272, 1295, 1326, 1375, 1476, 1509, 1556, 1579, 1594, 1641, 1678, 1754, 2005, 2074, 2232, 2299, 2367, 2699, 2812, 2855, 2973, 3088, 3106, 3231, 3252, 3659, 3713, 3769, 3826, 3845, 3893, 4203, 4428, 4443, 4553, 4590, 4645, 4673, 4695, 4721, 4758, 4792, 4831, 4989, 5030, 5073, 5129, 5146, 5274, 5379, 5402, 5482, 5540, 5597], 'Scopus': [542, 557, 694, 777, 866, 912, 975, 1036, 1070, 1125, 1186, 1205, 1273, 1327, 1376, 1477, 1510, 1557, 1595, 1642, 1700, 1755, 2006, 2075, 2233, 2300, 2368, 2700, 2813, 2856, 2974, 3089, 3107, 3232, 3253, 3660, 3714, 3770, 3827, 3846, 4204, 4444, 4554, 4591, 4646, 4696, 4722, 4759, 4832, 4990, 5031, 5074, 5130, 5147, 5275, 5380, 5403, 5483, 5541, 5598], '(50)': [543, 5276], 'Google': [544, 559, 573, 696, 714, 732, 746, 763, 779, 868, 891, 914, 935, 977, 1038, 1050, 1072, 1127, 1171, 1188, 1207, 1275, 1296, 1329, 1378, 1479, 1512, 1559, 1580, 1597, 1644, 1679, 1702, 1757, 2008, 2077, 2235, 2302, 2370, 2702, 2815, 2858, 2976, 3091, 3109, 3234, 3255, 3662, 3716, 3772, 3829, 3848, 3894, 4206, 4429, 4446, 4556, 4593, 4648, 4674, 4698, 4724, 4761, 4793, 4834, 4992, 5033, 5076, 5132, 5149, 5277, 5382, 5405, 5485, 5543, 5600], 'Scholar,': [545, 560, 697, 715, 733, 747, 764, 892, 915, 1039, 1051, 1172, 1189, 1276, 1560, 1581, 3092, 3235, 3830, 4430, 4725, 5133, 5383], '4Haas': [546], '1975;': [553], '52:': [554], '377-383Crossref': [555], '(26)': [558], '5Park': [561], 'S.M.': [562], 'Lu': [563], 'C.D.': [564, 846, 884, 1195], 'Abdelal': [565], 'A.T.': [566], 'Bacteriol.': [568, 741, 772, 886, 930, 1045, 1065, 1166, 1291, 1575, 1674, 3102, 4424, 4669, 4788], '1997;': [569, 931, 1167, 1292, 1576, 1675, 1697, 3103, 4425, 4670, 4789], '179:': [570, 932, 1168, 1293, 1577, 1676, 3104, 4426, 4671, 4790], '5309-5317Crossref': [571], 'A': [575, 1090, 1769, 1819, 1869, 1955, 1971, 2125, 2128, 2142, 3385, 4519, 5012, 5565], 'more': [576, 2539], 'complicated': [577], 'situation': [578, 5567], 'arises': [579], 'branched': [581], 'where': [584, 4464, 4528, 5574], 'products': [587, 793, 1409], 'may': [588, 5568], 'exert': [589], 'control': [590, 1431, 4305], 'functions': [591], 'several': [593], 'checkpoints.': [594], 'instance,': [596], 'aromatic': [598, 663, 942, 1411, 3307, 3342, 4887], 'P.': [601, 666, 840, 902, 921, 1101, 1157, 1252, 1263, 1282, 1312, 1366, 1448, 1500, 1533, 1547, 1566, 1627, 1665, 1688, 1711, 2031, 2285, 2353, 2690, 2708, 2803, 2846, 2873, 2964, 3115, 3554, 3645, 3699, 3760, 3995, 4000, 4167, 4415, 4453, 4660, 4681, 4712, 4779, 4822, 4890, 4973, 4980, 5010, 5038, 5064, 5473, 5511, 5526], '(Fig.': [603, 654, 832, 949, 1720, 3206, 3353, 3495, 3545, 3608, 4330, 4892, 5016, 5180, 5190, 5320, 5430], '1),': [604, 833], 'tryptophan': [605, 678, 3310], 'isoenzyme': [608, 634], 'carrying': [609, 2711, 5448, 5460], 'out': [610, 5331], 'reaction': [613, 1300, 2404, 2450, 2612, 4562, 5427, 5557], '(AroA)': [614], 'and,': [615, 5289], 'addition,': [617, 3963], 'tryptophan-specific': [621], 'anthranilate': [623, 5082], '(TrpEG).': [625], 'Tyrosine': [626], 'causes': [627, 953], 'AroA': [633], 'tyrosine-specific': [637], 'enzymes.': [638], 'Furthermore,': [639, 3320, 4558], 'tyrosine': [640, 3313], 'activates': [641], 'phenylalanine': [643, 651, 3317], '(AroQ-PheA)': [648], 'branch': [653, 680, 938], '1).': [655, 950, 4893], 'Repression': [656], 'plays': [657], 'relatively': [659], 'minor': [660], 'appears': [669], 'be': [671, 1355, 3449, 3733, 5284, 5502, 5559], 'limited': [672, 3438, 3811], 'three': [674, 2743, 2892, 2919, 3054, 4063, 4243], 'steps': [675, 2745, 4605], '(6Calhoun': [681], 'D.H.': [682, 749, 4579], 'Pierson': [683, 700], 'D.L.': [684, 701], 'Jensen': [685, 702, 720, 738, 756, 769], 'R.A.': [686, 703, 721, 739, 757, 770], 'Mol.': [687, 905, 1200, 1266, 1369, 1503, 1550, 2069, 2693, 2806, 2849, 2967, 3763, 4547, 4715, 4825, 4983, 5067, 5476], 'Gen.': [688, 906, 1267, 1370, 1504, 1551, 2694, 2807, 2850, 2968, 3764, 4548, 4716, 4826, 5068, 5477], 'Genet.': [689, 907, 1268, 1371, 1505, 1552, 2695, 2808, 2851, 2969, 3765, 4549, 4717, 4827, 5069, 5478], '1973;': [690, 2071], '121:': [691], '117-132Crossref': [692], '(30)': [695, 3254], '7Patel': [698], 'N.': [699, 3079, 3222, 4583], 'Biol.': [705, 723, 759, 1316, 1631, 2070, 2289, 2357, 3649, 3703, 3885, 4685, 5372, 5395, 5530], 'Chem.': [706, 724, 1317, 1632, 1696, 2290, 2358, 3650, 3704, 3886, 4686, 5371, 5394, 5531], '1977;': [707], '252:': [708], '5839-5846Abstract': [709], 'Full': [710, 728, 1321, 1323, 1636, 1638, 2294, 2296, 2362, 2364, 3654, 3656, 3708, 3710, 3890, 4690, 4692, 5376, 5399, 5535, 5537], 'Text': [711, 729, 1322, 1324, 1637, 1639, 2295, 2297, 2363, 2365, 3655, 3657, 3709, 3711, 3891, 4691, 4693, 5377, 5400, 5536, 5538], 'PDF': [712, 730, 1325, 1640, 2298, 2366, 3658, 3712, 3892, 4694, 5378, 5401, 5539], '8Whitaker': [716], 'R.J.': [717, 737], 'Gaines': [718], 'C.G.': [719], '1982;': [725], '257:': [726], '13550-13556Abstract': [727], '9Fiske': [734], 'M.J.': [735], 'Whitaker': [736], '1983;': [742], '154:': [743], '623-631Crossref': [744], '10Calhoun': [748], 'Bonner': [750, 767], 'C.A.': [751, 768, 3883, 5267], 'Gu': [752], 'W.': [753, 1611, 5214], 'Xie': [754], 'G.': [755, 766, 3241, 4546, 5139, 5590], 'Genome': [758], '2001;': [760, 773, 1066, 5143, 5271, 5594], '2:': [761], '30.1-30.16Crossref': [762], '11Gosset': [765], '183:': [774, 1067], '4061-4070Crossref': [775], '(47)': [778], 'It': [781, 4994, 5297, 5545], 'note': [785], 'that,': [786], 'examples': [789], 'cited,': [790], 'metabolites.': [796, 817], 'question': [798, 4462], 'concerns': [800], 'us': [801], 'here': [802], 'whether': [804, 4370, 4999], 'same': [806, 5458], 'general': [807], 'rules': [808], 'also': [809, 1437, 2192, 2937, 3210, 3684, 3898, 4281, 4359, 4934, 5283, 5517, 5570], 'apply': [810], 'bacterial': [813, 4470, 4598], 'production': [814, 3808, 4350, 4530], 'As': [818, 5052], 'we': [821, 1210, 1398, 2704, 3371, 3602, 3723, 4307, 4335, 4458, 4495], 'will': [822], 'consider': [823], 'precursor': [830], 'produced': [836, 1387], 'excreted': [838], 'during': [842, 2663, 2979, 3931, 4950], 'limitation': [844], '(12Cox': [845], 'Rinehart': [847, 881], 'Jr.,': [848, 853], 'K.': [849, 1043, 3243, 4976], 'Moore': [850], 'M.L.': [851, 1113, 1199], 'Cook': [852], 'Proc.': [855, 1114], 'Natl.': [856, 1115], 'Acad.': [857, 1116, 4585], 'Sci.': [858, 1117, 4586], 'U.': [859, 1109, 1118], 'S.': [860, 1119, 3834, 4192], 'A.': [861, 880, 1120, 1471, 1749, 1806, 1850, 2226, 4575, 5118, 5265], '1981;': [862], '78:': [863], '4256-4260Crossref': [864], '(308)': [867], 'Pyochelin': [870], 'synthesis': [871, 3466, 3569, 3988, 4921, 5008], 'starts': [872], '(13Ankenbauer': [875], 'R.G.': [876], 'Toyokuni': [877], 'Staley': [879], 'K.L.': [882], 'Cox': [883, 1194], '1988;': [887], '170:': [888], '5344-5351Crossref': [889], '14Serino': [893, 4703], 'L.': [894, 917, 965, 1026, 1057, 1153, 1176, 1255, 1278, 1358, 1492, 1539, 1562, 1585, 1661, 2682, 2795, 2838, 2956, 3752, 3817, 4411, 4434, 4656, 4704, 4749, 4775, 4814, 5056, 5114, 5465, 5604], 'Reimmann': [895, 918, 1154, 1256, 1279, 1359, 1493, 1540, 1563, 1662, 2683, 2796, 2839, 2957, 3753, 4412, 4657, 4705, 4776, 4815, 5057, 5466], 'C.': [896, 919, 963, 1024, 1053, 1155, 1174, 1257, 1280, 1310, 1360, 1494, 1541, 1564, 1583, 1625, 1663, 1686, 2283, 2351, 2684, 2797, 2840, 2958, 3237, 3643, 3697, 3754, 3815, 4413, 4432, 4658, 4679, 4706, 4747, 4777, 4816, 5058, 5263, 5467, 5524], 'Baur': [897, 1258, 1361, 1495, 1542, 2685, 2798, 2841, 2959, 3755, 4707, 4817, 5059, 5468], 'H.': [898, 1259, 1362, 1496, 1543, 2686, 2799, 2842, 2960, 3756, 4708, 4818, 5060, 5469], 'Beyeler': [899, 922, 966, 1027, 1158, 1177, 1260, 1283, 1363, 1497, 1544, 1567, 1586, 1666, 2687, 2800, 2843, 2961, 3757, 3818, 4416, 4435, 4661, 4709, 4750, 4780, 4819, 5061, 5470], 'M.': [900, 923, 967, 1028, 1059, 1159, 1178, 1261, 1284, 1364, 1498, 1545, 1568, 1587, 1667, 1999, 2067, 2688, 2801, 2844, 2962, 3758, 3819, 4417, 4436, 4662, 4710, 4751, 4781, 4820, 4982, 5062, 5471], 'Visca': [901, 920, 1156, 1262, 1281, 1365, 1499, 1546, 1565, 1664, 2689, 2802, 2845, 2963, 3759, 4414, 4659, 4711, 4778, 4821, 5063, 5472], 'Haas': [903, 927, 968, 1029, 1062, 1163, 1179, 1264, 1288, 1313, 1367, 1501, 1548, 1572, 1588, 1628, 1671, 2286, 2354, 2691, 2804, 2847, 2965, 3646, 3700, 3761, 3820, 4421, 4437, 4666, 4682, 4713, 4752, 4785, 4823, 5065, 5474, 5527], '1995;': [908, 1269, 1372, 1506, 1553, 2696, 2809, 2852, 2970, 3766, 4718, 4828, 5070, 5479], '249:': [909, 1270, 1373, 1507, 1554, 2697, 2810, 2853, 2971, 3767, 4719, 4829, 5071, 5480], '217-228Crossref': [910, 1271, 1374, 1508, 1555, 2698, 2811, 2854, 2972, 3768, 4720, 4830, 5072, 5481], '(152)': [913, 1274, 1377, 1511, 1558, 2701, 2814, 2857, 2975, 3771, 4723, 4833, 5075, 5484], '15Serino': [916, 1277, 1561], 'Della': [924, 1160, 1285, 1569, 1668, 4418, 4663, 4782], 'Chiesa': [925, 1161, 1286, 1570, 1669, 4419, 4664, 4783], '248-257Crossref': [933, 1169, 1294, 1578, 1677, 4427, 4672, 4791], 'Scholar),': [936, 1330, 1379, 1703, 2371, 2703, 3110, 4649, 4675, 4699, 5077, 5222], 'point': [939], 'intermediate': [940, 3514], 'biosynthesis,': [943, 1221, 1412, 5253], 'uses': [945], 'molecules': [947], 'ofl-cysteine': [948], 'Interestingly,': [951], 'induction': [954, 4257, 4299], 'rather': [955, 1427], 'than': [956, 1428, 2540, 5327], '(16Reimmann': [962, 1023, 3814, 4746], 'Serino': [964, 1025, 1056, 1175, 1584, 1657, 3816, 4433, 4748], 'Microbiology.': [970, 1031, 1181, 1590, 3822, 4439, 4754, 5270], '1998;': [971, 1032, 1182, 1591, 3249, 3823, 4440, 4755, 5373, 5396], '144:': [972, 1033, 1183, 1592, 3824, 4441, 4756], '3135-3148Crossref': [973, 1034, 1184, 1593, 3825, 4442, 4757], '(107)': [976, 1037, 1187, 1328, 1596, 1643, 2301, 2369, 3661, 3715, 3828, 4445, 4697, 4760, 5542], 'mechanism': [980, 1093], 'autoinduction': [983], 'not': [985, 2536, 2770, 3005, 3014, 3153, 3189, 3331, 3406, 3535, 3690, 4301, 4372, 4491, 4915, 4923, 4996, 5159, 5435], 'entirely': [986], 'clear': [987], 'but': [988, 5420, 5578], 'probably': [989], 'involves': [990], 'initial': [992], 'interaction': [993], 'outer': [998], 'membrane': [999], 'receptor,': [1000], 'FptA,': [1001], 'followed': [1002, 2435, 4282], 'activation': [1004, 3270], 'PchR,': [1009], 'turns': [1011], 'transcription': [1014], 'operons': [1019, 4409], 'pchEFGHI': [1022], '17Heinrichs': [1040], 'D.E.': [1041], 'Poole': [1042], '1993;': [1046], '175:': [1047], '5882-5889Crossref': [1048], '18Reimmann': [1052], 'Patel': [1054, 4637], 'H.M.': [1055, 4638], 'Barone': [1058], 'Walsh': [1060, 3082, 3225, 4639, 5369, 5392], 'C.T.': [1061, 3083, 3226, 4640, 5370, 5393], '813-820Crossref': [1068], '(97)': [1071, 1206], 'transduction': [1077], 'product': [1081, 1241, 2453, 3287], 'unlikely': [1084], 'accumulate': [1086], 'cytoplasm.': [1089], 'similar': [1091, 1744, 4520, 5566], 'has': [1094, 1438, 3209, 4522, 5194, 5298, 5347, 5582], 'been': [1095, 1488, 1535, 2942, 3211, 4523, 4610, 4967, 5299, 5348, 5583], 'observed': [1096, 1356, 3184, 3212, 4492], 'another': [1098, 4304, 4970, 5499], 'pyoverdin': [1103, 1149], '(19Lamont': [1104], 'I.L.': [1105], 'Beare': [1106], 'P.A.': [1107], 'Ochsner': [1108], 'Vasil': [1110, 1112, 1196, 1198], 'A.I.': [1111, 1197], '2002;': [1121, 1318, 1633, 2291, 2359, 3651, 3705, 4687, 4986, 5532], '99:': [1122], '7072-7077Crossref': [1123], '(438)': [1126], 'When': [1129], 'cells': [1130, 1393, 3380], 'have': [1131, 1487, 4459, 4606, 4965, 5228, 5408, 5436], 'accumulated': [1132], 'excess': [1133, 2642, 3453, 4313], 'Fur': [1136, 4767], 'repressor': [1137, 4768], 'activated,': [1139], 'switches': [1141], 'off': [1142], 'genes': [1151, 2718, 3613, 4805, 5227, 5281, 5356], '(15Serino': [1152, 1660, 4410, 4655, 4774], '16Reimmann': [1173, 1582, 4431], '20Barton': [1190], 'H.A.': [1191], 'Johnson': [1192], 'Z.': [1193], 'Microbiol.': [1201], '1996;': [1202, 4550, 4587], '21:': [1203], '1005-1017Crossref': [1204], 'Here,': [1209, 1397], 'ask': [1211], 'how': [1212, 3592], '(ICS1;': [1224], 'EC': [1225], '5.4.99.6),': [1226], 'regulated.': [1228], 'catalyzes': [1231], 'conversion': [1233, 3954, 4945, 5334], 'operon': [1250, 4733], '(14Serino': [1254, 1357, 1491, 1538, 2681, 2794, 2837, 2955, 3751, 4813, 5055, 5464], 'subsequent': [1299], 'catalyzed': [1302, 3194, 4563, 5494], 'pchB': [1305, 1344, 2675, 5345], 'product,': [1306, 4489], 'pyruvate-lyase': [1308, 1385, 3641, 3679, 4677, 5556], '(21Gaille': [1309, 1624, 2282, 2350, 3642, 3696, 4678, 5523], 'Kast': [1311, 1626, 1687, 2284, 2352, 3644, 3698, 4680, 5525], '277:': [1319, 1634, 2292, 2360, 3652, 3706, 4688, 5533], '21768-21775Abstract': [1320, 1635, 2293, 2361, 3653, 3707, 4689, 5534], 'produces': [1332], '(Fig.1).': [1334], 'co-expressed': [1340], 'upstream': [1343], 'gene;': [1345], 'withoutpchB': [1346], 'being': [1347, 4296], 'present': [1348, 2678], 'cis': [1350, 2680], 'no': [1351, 3339, 4288, 4904, 5196, 5344, 5422, 5579], 'ofpchA': [1353], 'suggesting': [1380, 4917, 5223], 'ICS': [1382, 1402, 2399, 2629, 3071, 3272, 3334, 4701, 5156, 5184, 5226, 5280, 5317, 5355, 5413], 'proportional': [1389], 'amounts': [1390], 'under': [1394, 2730, 3276, 3382], 'circumstances.': [1396], 'report': [1399], 'ofP.': [1403], 'insensitive': [1406], 'particular': [1414], 'salicylate,': [1416, 2459, 3990, 5338, 5455], 'essentially': [1423, 5101], 'enzyme.': [1435, 3362], 'implications': [1439], 'productivity': [1442, 3597, 4512, 4852], 'pathway.': [1447], 'strains': [1450], 'PAO1': [1451, 3377, 3556, 4329], '(wild': [1452], 'type)': [1453], 'ADD1976': [1455, 1713, 2710], '(PAO1': [1456], 'T7': [1459, 1716, 2721], 'RNA': [1460], 'polymerase,': [1461], 'chromosomally': [1462, 4292], 'expressed': [1463, 2671, 3734], 'lac': [1466], 'promoter)': [1467], '(25Brunschwig': [1468, 1746], 'E.': [1469, 1610, 1747, 3217, 3245, 3836, 4194, 5360, 5446], 'Darzins': [1470, 1748], 'Gene.': [1472, 1750], '1992;': [1473, 1751], '111:': [1474, 1752], '35-41Crossref': [1475, 1753], '(68)': [1478, 1756], 'Scholar)': [1480, 1680, 2009, 2078, 2859, 4207, 4762, 5034], 'plasmid': [1484, 1517, 3606, 4008, 4175], 'pME3359': [1485, 1719], '(PT7-pchBA)': [1486], 'described': [1489, 1622, 1736, 2281, 2729], 'previously': [1490, 1623, 5054], 'construction': [1515], 'pME3395': [1518, 3607, 5449], 'detailed': [1520], 'legend': [1523], 'Fig.2.': [1525], 'Media': [1526], 'culture': [1528, 4053], 'conditions': [1529, 3279, 3479], 'growth': [1531, 3796, 4041, 4317, 4909, 4912, 4941, 4951], 'aeruginosahave': [1534], 'given': [1536, 4056, 4236], 'elsewhere': [1537], 'Sodium': [1599], 'isochorismate,': [1600, 3571], 'used': [1601, 2176, 2277, 3798], 'reference,': [1604], 'kind': [1607], 'gift': [1608, 5616], 'Leistner': [1612, 3244, 5613], '(University': [1613], 'Cologne)': [1615], 'prepared': [1618, 1652, 1709, 3372], 'Racemic': [1646], '(Dha)': [1648], 'methods': [1655], 'et': [1658, 1683], 'al.': [1659, 1684], 'Grisostomi': [1682], '(26Grisostomi': [1685], 'Pulido': [1689], 'R.': [1690, 3094, 3100, 3239, 3832, 4190], 'Huynh': [1691], 'Hilvert': [1693], 'Bioorg.': [1695], '25:': [1698], '297-305Crossref': [1699], '(43)': [1701], 'respectively.': [1704, 2610], 'Crude': [1705, 1785], 'extracts': [1707, 3000], 'harboring': [1714], 'promoter': [1717, 2722, 3744, 4730], 'construct': [1718, 3793], '2)': [1721, 3609], '750': [1725], 'ml': [1726, 1816, 1866, 1906, 2440, 4018, 4185], 'nutrient': [1728], 'yeast': [1729], 'broth': [1730], 'isopropyl-औ-d-thiogalactopyranoside': [1732], '(IPTG)': [1733], 'induction,': [1734], 'extraction': [1739, 2437], 'PchB': [1741, 2345, 2517, 2617, 2644, 2934, 2949, 3012, 3533, 3672, 3694, 4278, 4294, 5508, 5580], 'strain': [1745, 4328, 4895, 4971, 5459], 'Extracts': [1759], 'contained': [1760], '∼8': [1761], 'mg': [1762], 'per': [1765, 2396, 3408], 'milliliter': [1766], 'buffer': [1768, 1805, 1818, 1849, 1868, 1921, 1954, 1970, 2124, 2521], '(50': [1770], 'mm': [1771, 1935, 1958, 2330, 2574, 2580, 2606, 3129, 3148], 'potassium': [1772, 1959, 2575], 'phosphate': [1773, 2320, 2576], 'buffer,': [1774, 2321], '7.5,': [1776, 2200], 'containing': [1777, 1829, 1956, 2572, 3390, 3855, 4023, 4208], '107': [1778, 2326, 2583], '(v/v)': [1779, 1909, 1927, 1931, 2327], 'glycerol': [1780, 2584, 3801, 4024, 4209], '1': [1782, 1825, 1871, 1934, 1977, 2329, 2389, 2527, 2579, 2605, 3128, 4047, 4230], 'mmdithiothreitol': [1783], '(DTT)).': [1784], 'extract': [1786, 3375, 3389, 3445, 3541, 3557], '(15': [1787], 'ml)': [1788, 1832, 1982], 'applied': [1790], 'DEAE-Sepharose': [1793], 'CL-6B': [1794], 'column': [1795, 1813, 1839, 1863, 1946, 1967], '(1.6': [1796, 1843, 2107, 2116], '×': [1797, 1844, 2108, 2117], '20': [1798], 'cm)': [1799, 1846], 'equilibrated': [1800, 1847, 1951], '10': [1802, 1845, 1923, 1957, 2324, 2428, 2595, 2608, 3147], 'volumes': [1803, 2158], 'eluted': [1809, 1859, 1877, 1902, 1963, 2988], 'washing': [1811, 1861, 1965], '300': [1815], 'flow': [1822, 1974], 'ml/min.': [1826, 1872, 1978], 'fractions': [1828, 1980], '(180': [1831], 'combined': [1834], 'loaded': [1836, 1940], 'onto': [1837, 1941], 'phenyl-Sepharose': [1841], 'CL-4B': [1842], 'Most': [1851], 'contaminant': [1854], 'proteins,': [1855], 'including': [1856], 'PchB,': [1857, 3399], '200': [1865, 4017, 4184], 'More': [1873], 'hydrophobic': [1874], 'proteins': [1875, 5212, 5326, 5493], 'step': [1880, 2758, 2983, 4570], 'gradient': [1881], 'ethylene': [1883, 1910, 1928], 'glycol': [1884], 'follows:': [1886], '257': [1887], '(v/v),': [1888, 1892, 1897], '60': [1889, 1893], 'ml;': [1890, 1894], '25–407': [1891], '407': [1896, 1908], '65': [1898], 'ml.': [1899], 'about': [1904, 2270, 2766], '40': [1905], 'glycol.': [1911], 'fraction': [1913, 2751, 3854], 'diluted': [1915], 'five': [1916], 'times,': [1917], 'resulting': [1918], 'mmpotassium': [1924, 2319], 'phosphate,': [1925], '87': [1926], 'glycol,': [1929], '27': [1930], 'glycerol,': [1932, 2328], 'DTT,': [1936, 2331, 2581], 'MonoQ': [1943, 2756], 'HR': [1944, 2882], '5/5': [1945], '(fast': [1947], 'liquid': [1949, 2339], 'chromatography)': [1950], 'modified': [1953], 'phosphate.': [1960], 'standard': [1969, 2259, 2488, 2519, 3277], 'PchA-containing': [1979], '(4': [1981], 'pooled': [1984], 'stored': [1986], '−80°C.': [1988], 'Protein': [1989], 'concentrations': [1990, 2524, 2603, 3965], 'method': [1995], 'Bradford': [1997], '(27Bradford': [1998], 'Anal.': [2000, 2227], '1976;': [2002], '72:': [2003], '248-254Crossref': [2004], '(222903)': [2007], 'using': [2010, 2046, 2079, 2465, 2553, 3904], 'commercial': [2012], 'reagent': [2013], '(Bio-Rad)': [2014], 'bovine': [2016, 2149], 'serum': [2017, 2150], 'albumin': [2018, 2151], 'standard.': [2021, 2091], 'N-terminal': [2023, 2818, 2865], 'sequence': [2024, 2788, 2821, 2835, 5014, 5097, 5188, 5204], 'Dr.': [2030], 'James': [2032], '(Eidgenössische': [2033], 'Technische': [2034], 'Hochschule,': [2035], 'Zürich,': [2036], 'Switzerland)': [2037], 'Applied': [2040], 'Biosystems': [2041], 'peptide': [2042], 'sequencer': [2043], 'model': [2044], '473A': [2045], 'Edman': [2047, 2829], 'degradation.': [2048], 'subunit': [2050, 2773], 'molecular': [2051, 2082, 2093, 2165, 2181, 2186, 2210, 2254, 2774, 3038], 'mass': [2052, 2094, 2182, 2187, 2255, 2775], 'estimated': [2056, 2099, 2193, 3018], 'SDS-PAGE': [2058, 2748], 'according': [2059, 2724], 'Lämmli': [2061], 'Favre': [2063, 2066], '(28Lämmli': [2064], 'U.K.': [2065], '80:': [2072], '575-599Crossref': [2073], '(3072)': [2076], 'low': [2081, 2209], 'weight': [2083, 2211], 'calibration': [2084, 2212], 'kit': [2085, 2213], 'Amersham': [2087], 'Biosciences': [2088, 2215], 'gel': [2101, 2996, 3020], 'filtration': [2102, 2997], 'chromatography': [2103, 2757, 3022], 'Sephadex': [2105, 3024], 'G-150': [2106, 3025], '70': [2109, 2118], 'cm,': [2110, 2119], '0.1': [2111, 2120], 'ml/min)': [2112, 2121], 'Bio-Gel': [2114, 3002, 3027], 'P100': [2115, 3003, 3028], 'columns': [2122], 'ribonuclease': [2127], '(13.7': [2129], 'kDa),': [2130, 2133, 2137, 2140, 2144, 2147], 'lysozyme': [2131], '(14.6': [2132], 'proteinase': [2134], 'K': [2135], '(28.8': [2136], 'pepsin': [2138], '(34.5': [2139], '(42': [2143], 'ovalbumin': [2145], '(43': [2146], '(67': [2152], 'kDa)': [2153, 2783], 'markers.': [2155], 'elution': [2157], 'plotted': [2160, 2251], 'against': [2161, 2252], 'logarithm': [2163, 2244], 'masses': [2166, 3039], 'standards,': [2169], 'linear': [2172], 'regression': [2173], 'curve': [2174, 2489], 'estimate': [2178], 'PchA.': [2184, 2377, 3265], 'PAGE': [2195, 3032], 'non-denaturing': [2197], 'gels': [2198], '10,': [2201], '12,': [2202], '15,': [2203], '207': [2205], 'polyacrylamide,': [2206], 'fromAmersham': [2214], 'standard,': [2218], 'Ferguson': [2220], 'plot': [2221], 'analysis': [2222, 4267], '(29Tietz': [2223], 'Chrambach': [2225], '1987;': [2229], '161:': [2230], '395-411Crossref': [2231], '(49)': [2234], 'slopes': [2238], 'obtained': [2239, 2446, 2490, 2752, 2827, 3051], 'plots': [2241], 'relative': [2246], 'mobilityversus': [2247], 'polyacrylamide': [2248, 3035], 'values': [2256, 2534, 4055, 4235], 'proteins.': [2260], 'Rabbit': [2261], 'polyclonal': [2262], 'antibodies': [2263], 'generated': [2265], 'subcutaneous': [2267], 'injection': [2268], '410': [2271], 'ॖg': [2272, 2509, 2515, 3410], 'immunoblots': [2279], 'Unless': [2304], 'otherwise': [2305], 'stated,': [2306], 'incubation': [2308, 2520, 2570, 3135, 3199, 3428], 'mixture': [2309, 2571, 3136], 'contained,': [2310], 'final': [2313, 2755], 'volume': [2314], '500': [2316, 2332, 2529, 3425, 3529], 'ॖl,': [2317], '100': [2318, 2573, 2621, 3421], 'mmMgCl2,': [2325], '(purified': [2335], 'pressure': [2338], 'chromatography),': [2340], '48': [2341, 3041], 'units': [2342, 2375, 2650], '(corresponding': [2346], '3.7': [2348, 2514], 'ॖg)': [2349, 2588, 2619], '≤': [2373], '2': [2374, 3050, 3909, 3949], 'One': [2378], 'unit': [2379, 4034, 4219], 'defined': [2384], 'nmol': [2390], '(assayed': [2393], 'salicylate)': [2395], 'minute': [2397], 'pyruvate-lyase.': [2402], '37': [2406, 2592, 4014, 4181], '°C': [2407, 2593, 4015, 4182], 'initiated': [2409], 'addition': [2412, 2426, 3145, 3282, 3322, 3527, 3919, 3947, 4311, 4902], 'solution': [2418], 'terminated': [2420], 'after': [2421, 2626, 2753, 2989, 3280], '5': [2422, 2627], 'min': [2423, 3491, 3494], 'ॖl': [2429, 3426], 'concentrated': [2431], 'HCl': [2432], '(10': [2433, 3295], 'm),': [2434], '3': [2439], 'ethyl': [2442, 2497], 'acetate.': [2443, 2498], 'Blanks': [2444], 'non-incubated': [2448], 'complete': [2449], 'mixtures.': [2451], 'coupled': [2456, 2635, 3484], 'enzymatic': [2457, 2953], 'reaction,': [2458, 3486], 'measured': [2461, 2632, 3779], 'fluorescence': [2464], 'excitation': [2467], 'wavelength': [2468, 2475], '305': [2470], 'nm': [2471], 'emission': [2474], '440': [2477], 'nm.': [2478], 'amount': [2480, 4276, 4536], 'formed': [2483, 2657], '0.5–8': [2492], 'salicylic': [2494], 'acid': [2495, 2820], 'Assays': [2499], 'kinetic': [2501, 2533], 'studies': [2502], 'performed': [2504], 'triplicate': [2506], '0.96': [2508], 'varying': [2525, 3034], 'ॖm.': [2530], 'steady-state': [2532], 'did': [2535, 3004, 3330, 3534, 5434, 5463], 'vary': [2537], '±': [2541, 2902, 2929, 3042, 3045, 3049, 3170, 3178, 4060, 4073, 4075, 4077, 4079, 4081, 4083, 4085, 4087, 4090, 4092, 4094, 4096, 4098, 4100, 4102, 4104, 4107, 4109, 4111, 4113, 4115, 4117, 4119, 4121, 4124, 4126, 4128, 4130, 4132, 4135, 4137, 4139, 4141, 4143, 4145, 4149, 4151, 4153, 4155, 4157, 4159, 4161, 4163, 4240], '107.': [2542, 2903, 2930], 'Initial': [2543], 'velocity': [2544], 'data': [2545, 2836, 4930], 'fitted': [2547], 'equation': [2550], 'Hanes,': [2552], 'Enzpack': [2554], 'software': [2555], '(Biosoft).': [2556], 'influence': [2558], 'Mg2+': [2560], 'studied': [2567], '(v/v).': [2585], '(3.9': [2587], 'preincubated': [2590], 'min.': [2596, 2628], 'EDTA': [2597, 3130], 'MgCl2': [2599, 3149], 'added': [2601, 3507], 'mm,': [2609], 'started': [2614], 'adding': [2616], '(0.54': [2618], 'stopped': [2625], 'assay': [2636, 3278], 'presence': [2639, 3120, 3419, 4743, 4771], '(typically': [2645], '∼30-fold': [2646], 'respect': [2648], 'activity).': [2653, 3143], 'Thus,': [2654, 3336, 4836], 'converted': [2659], 'quantitatively': [2660], 'incubation.': [2665], 'Because': [2666], 'only': [2672], 'when': [2673, 3451, 3737], 'isolated': [2705], 'pME3359,': [2712], 'expresses': [2714], 'pchBA': [2717, 4804], '(Fig.2),': [2723], 'purification': [2727, 2899, 2926, 2933], 'scheme': [2728], '"Experimental': [2731], 'Procedures."': [2732], '587': [2740], 'yield': [2741, 4913, 4955], 'chromatographic': [2744, 2982], '(Table': [2746, 3978, 4517], 'I).': [2747], 'indicated': [2759], '≥': [2761], '987': [2762], 'pure': [2763], '50': [2767, 3044, 3048], 'kDa': [2768], '(data': [2769, 3013, 3152, 3188, 3405, 3689, 4300, 4914], 'shown).': [2771, 3015, 3154, 3190, 4302], 'good': [2778, 3747], 'agreement': [2779], '(52.1': [2782], 'calculated': [2784], 'deduced': [2787], '476': [2790], 'amino': [2791, 2819, 3308, 3343, 3865], 'acids': [2792, 3309, 3344, 3866], 'residues': [2793], 'polypeptide': [2825], '(Ser-Arg-Leu-Ala-Pro-Leu-Ser-Gln)': [2826], 'degradation': [2830], 'matched': [2831], 'predicted': [2833], 'indicates': [2861], 'cleavage': [2862, 3858], 'methionine.Table': [2866], 'IPurification': [2867], 'ADD1976/pME3359Purification': [2875], 'stepProteinActivitySpecific': [2876], 'activityYieldPurificationmgunitsunits/mg7-foldCrude': [2877], 'extract13310,369781001DEAE-Sepharose': [2879], 'CL-6B31.68,814279853.6Phenyl-Sepharose': [2880], 'CL-4B8.07,1058906911.4MonoQ': [2881], '5/53.66,0151,6715821.4Data': [2883], 'shown': [2884, 2911], 'taken': [2886, 2913], 'typical': [2889, 2916], 'preparation.': [2890, 2917], 'independent': [2893, 2920, 4064, 4244], 'experiments,': [2894, 2921], 'reproducibility': [2896, 2923], 'factors': [2900, 2927], 'Open': [2904, 4250], 'table': [2905, 4251], 'new': [2908, 4254], 'tab': [2909, 4255], 'Data': [2910], 'During': [2931, 3942], 'followed,': [2938], 'there': [2940, 3337, 4286, 5000], 'had': [2941], 'previous': [2944], 'speculation': [2945], 'might': [2950, 5282, 5329, 5558], 'form': [2951], 'complex': [2954], 'However,': [2978, 3266, 4595, 5151], 'DEAE-Sepharose,': [2985], 'separated': [2992], 'PchB.': [2994, 3523], 'Moreover,': [2995], 'crude': [2999, 3374, 3553], 'reveal': [3006], 'any': [3007], 'association': [3008], 'exclusion': [3021], 'concentrations.': [3036], '2,': [3043, 3046], 'methods,': [3055], 'respectively,': [3056], 'indicate': [3057, 3549], 'exists': [3061], 'monomer.': [3064], 'Like': [3065], 'entC': [3067, 5443], 'andmenF': [3068], 'isoenzymes': [3069], 'having': [3070], '(30Liu': [3076, 3219], 'Quinn': [3078, 3221], 'Berchtold': [3080, 3223], 'G.A.': [3081, 3224], 'Biochemistry.': [3084, 3227, 4641], '1990;': [3085, 3228], '29:': [3086, 3229], '1417-1425Crossref': [3087, 3230], '(101)': [3090, 3233], '31Daruwala': [3093], 'Bhattacharyya': [3095], 'D.K.': [3096], 'Kwon': [3097], 'O.': [3098], 'Meganathan': [3099], '3133-3138Crossref': [3105], '(42)': [3108], 'aeruginosastrictly': [3116], 'pretreated': [3126], 'incubated': [3132, 3416], 'without': [3137, 3789, 4003, 4170], 'Mg2+,': [3138], 'inactive': [3140], '(≤': [3141], '1.17': [3142], 'restored': [3150], 'showed': [3156, 4269], 'hyperbolic': [3157], 'saturation': [3158], 'kinetics': [3159], 'substrate,': [3162], 'chorismate,': [3163], '0.5': [3171], '4.9': [3179], 'min−1.': [3180], 'Optimal': [3181], '7.0': [3187], 'chorismate-isochorismate': [3192], 'interconversion': [3193], 'reversible;': [3198], 'yielded': [3204], '3).': [3207], 'Reversibility': [3208], 'ICSs': [3215, 5047], '32Dahm': [3236], 'Müller': [3238], 'Schulte': [3240], 'Schmidt': [3242], 'Biochim.': [3246], 'Biophys.': [3247], 'Acta.': [3248], '1425:': [3250], '377-386Crossref': [3251], 'We': [3257, 3664, 3896, 5407, 5504, 5602], 'tested': [3258], 'range': [3260], 'potential': [3262], '<107': [3267], 'found': [3275, 5349, 5421, 5505, 5584], 'either': [3284], '(100': [3289, 3303, 3311, 3314, 3318], 'ॖm),': [3290, 3304, 3312], 'intermediates': [3293], 'ॖm)': [3296, 3315, 3325, 3329, 4869], '(Dha': [3299], 'Fig.': [3301], '1)': [3302, 3354], 'ॖm).': [3319], 'Fe2+(100': [3324], 'cysteine': [3327, 3962, 4937, 5007], '(200': [3328], 'significantly': [3332, 3951], 'alter': [3333], 'activity.': [3335, 3680], 'evidence': [3340, 5423], 'metabolites': [3346], 'inP.': [3351], 'regulate': [3356], 'To': [3363, 3578], 'determine': [3364, 4850], 'rate-limiting': [3366, 4569, 4604], 'production,': [3370], 'wild': [3378, 3784, 3975], 'type': [3379, 3785, 3976], 'limitation.': [3384], 'sample': [3386], '∼150': [3391], 'ng': [3392, 3397, 3530], '∼100': [3396], 'judged': [3401], 'Western': [3403, 4265, 4284], 'blots': [3404], 'shown)': [3407], '290': [3409], 'total': [3412], 'cellular': [3413], 'protein,': [3414], 'buffer.': [3429], 'Under': [3430], 'these': [3431, 4333, 5342], 'conditions,': [3432], '(Fig.4).': [3446], 'could': [3448], 'seen': [3450, 4369], '(500': [3454], 'ng)': [3455], 'added;': [3460], 'thereby,': [3461], 'increased': [3468, 3937, 3968], '∼3-fold': [3469], 'transient': [3472, 3501], 'time,i.e.': [3473], 'lag': [3475], 'before': [3476], 'steady': [3477], 'state': [3478], 'reached': [3481], 'shortened': [3488], '1.5': [3490], '<0.1': [3493], '4).': [3496, 3546], 'reduction': [3498, 4906], 'time': [3502], 'illustrates': [3503], 'fact': [3505], 'enhances': [3509, 4953], 'availability': [3511, 3594, 3813, 4838, 4938], 'extract,': [3522], 'By': [3524], 'contrast,': [3525], 'enhance': [3536], 'capacity': [3538], 'synthesize': [3543], 'These': [3547], 'results': [3548, 4334], 'i.e.': [3567, 4481], 'limits': [3572], 'production.': [3577], 'test': [3579], 'see': [3591], 'influences': [3595], 'constructed': [3603, 5186], 'thepchA': [3604, 3728], 'thepchBA': [3612], 'fused': [3615], 'inducible': [3618], 'tacpromoter': [3619], '(Ptac),': [3620], 'pchBfunction': [3623], 'inactivated': [3625], 'in-frame': [3628], 'deletion,': [3629], 'removing': [3630], 'notably': [3631], 'codon': [3633], 'essential': [3636], 'Ile-88': [3637], 'residue': [3638], 'verified': [3665], 'vivo': [3668, 3987, 4352], 'internally': [3670], 'truncated': [3671], 'totally': [3675], 'devoid': [3676], 'mutated': [3682], 'lacked': [3685], 'mutase': [3687, 5522], 'shown),': [3691, 4916], 'function': [3695, 4654], 'Using': [3718, 4448], 'somewhat': [3720], 'unconventional': [3721], 'construct,': [3722], 'overcame': [3724], 'problem': [3726], 'open': [3729], 'reading': [3730], 'frame': [3731], 'cannot': [3732], 'alone,': [3735], 'even': [3736], 'equipped': [3740], 'strong': [3743, 3925], 'ribosome': [3748], 'binding': [3749, 5107], 'site': [3750], 'Salicylate,': [3774], 'Dha,': [3775, 3991], 'PAO1,': [3786, 4002, 4169], 'PtacpchA': [3791], 'pME3395.': [3794], 'medium': [3797, 3906, 4021, 4188, 4318, 4374, 4942], '(GGP)': [3799], 'contains': [3800, 4375], 'proteose': [3803, 4026, 4211], 'peptone': [3804, 4027, 4212], 'favors': [3806], 'because': [3809, 5102, 5340], '33Carmi': [3831], 'Varmeli': [3833, 4191], 'Levy': [3835, 4193], 'Gough': [3837, 4195], 'F.G.': [3838, 4196], 'Nat.': [3840, 4198], 'Prod.': [3841, 4199], '1994;': [3842, 4200, 5027], '57:': [3843, 4201], '1200-1205Crossref': [3844, 4202], '(51)': [3847, 4205], 'Proteose': [3850], 'peptone,': [3851], 'milk': [3853], 'mostly': [3856], 'casein': [3857], 'rich': [3862], 'source': [3863], 'notable': [3869], 'exception': [3870], 'cysteine,': [3872], 'underrepresented': [3875], '(34Steele': [3876], 'B.F.': [3877], 'Sauberlich': [3878], 'H.E.': [3879], 'Reynolds': [3880], 'M.S.': [3881], 'Baumann': [3882], '1949;': [3887], '177:': [3888], '533-544Abstract': [3889], 'therefore': [3897, 5547], 'conducted': [3899], 'series': [3901], 'experiments': [3903], 'GGP': [3905, 4020, 4187], 'amended': [3907], 'mml-cysteine.': [3910], 'media,': [3913], 'driven': [3916], 'inducer': [3922], 'IPTG': [3923, 4259, 4901], 'caused': [3924, 4903], 'accumulation': [3927, 3938], 'stationary': [3932, 4961], 'phase,': [3933, 3945], 'concomitant': [3934], 'Dha': [3940], '(TableII).': [3941], 'late': [3943, 4071, 4248], 'exponential': [3944, 4908], 'mml-cysteine': [3950], 'pyochelin;': [3958], 'however,': [3959, 4998], 'irrespective': [3960], 'consistently': [3967], 'comparison': [3973, 5205], 'II).Table': [3979], 'IIEffects': [3980], 'aeruginosaPlasmid': [3996], 'PAO12-aCells': [3998], 'pchA+': [4007, 4174], 'pME3395,': [4009, 4176], 'aerobically': [4012, 4179], '(33)': [4022], 'OD600nm': [4030, 4033, 4215, 4218], 'indicated.': [4031, 4216], '1.0': [4032, 4217], 'corresponds': [4035, 4220], 'approx.': [4037, 4222], '109': [4038, 4223], 'cells/ml.Addition': [4039], 'medium2-bConcentration': [4042], 'supplements': [4044, 4227], 'IPTG,': [4046, 4229], 'mM;l-cysteine': [4048, 4231], '(Cys),': [4049, 4232], '2mm.Growth': [4050], 'phaseOD600nmConcentration': [4051], 'supernatant2-cThe': [4054], 'represent': [4057, 4237], 'means': [4059, 4239], 'S.D.': [4061, 4241], 'experiments.SalicylateDhaPyochelinnmol': [4065], 'ml−1nmol': [4066, 4067], 'ml−1NoneNoneLate': [4068], 'exp.2-dLate': [4069], 'exp.,': [4070, 4247], 'exponential.3.9': [4072], '0.29.0': [4074], '8.01.5': [4076], '1.3173.5': [4078], '24.0Stationary5.9': [4080], '0.527.4': [4082], '23.811.8': [4084], '3.2550.0': [4086], '81.3pME3395NoneLate': [4088], 'exp.3.2': [4089], '0.413.7': [4091], '2.96.4': [4093], '0.5307.8': [4095], '31.6Stationary5.9': [4097], '0.38.4': [4099], '7.949.1': [4101], '6.4741.4': [4103], '53.4pME3395IPTGLate': [4105], 'exp.4.1': [4106], '0.2267.6': [4108], '34.19.3': [4110], '0.4516.0': [4112], '10.3Stationary6.6': [4114], '0.5914.9': [4116], '130.773.5': [4118], '2.41007.6': [4120], '34.2NoneCysLate': [4122], 'exp.3.8': [4123], '0.2<8<1.2159.0': [4125], '19.2Stationary5.5': [4127], '0.1<85.1': [4129], '0.7730.8': [4131], '56.1pME3395CysLate': [4133], 'exp.3.5': [4134], '0.3<82.8': [4136], '0.2363.6': [4138], '9.0Stationary6.6': [4140], '0.1<860.1': [4142], '6.31314.8': [4144], '102.3pME3395Cys,': [4146], 'IPTGLate': [4147], 'exp.4.5': [4148], '0.116.8': [4150], '1.49.2': [4152], '1.21072.4': [4154], '96.6Stationary6.6': [4156], '0.2744.7': [4158], '85.7128.3': [4160], '44.01708.6': [4162], '210.82-a': [4164], 'Cells': [4165], '(33Carmi': [4189], 'cells/ml.2-b': [4224], 'Concentration': [4225], '2mm.2-c': [4233], 'experiments.2-d': [4245], 'Late': [4246], 'exponential.': [4249], 'monitored': [4261], 'parallel': [4263], 'blot': [4266], 'expected': [4271], 'pattern': [4273], '(Fig.5A).': [4274], 'blots;': [4285], 'indication': [4289], 'overexpressed': [4297], 'duringpchA': [4298], 'experiment': [4306], 'confirmed': [4308], 'completely': [4319], 'abolished': [4320], 'chromosomalpchA': [4325], '5B).': [4331], 'conclude': [4336], 'following.': [4338], '(i)': [4339], 'determines': [4345, 4360], 'bothin': [4351], 'vitro.': [4355], '(ii)': [4356], 'pyochelin,': [4364, 4957], 'effect': [4367], 'extra': [4377], 'supply': [4378], 'cosubstratel-cysteine.': [4381], '(iii)': [4382], 'Excess': [4383], 'brings': [4385], '(and': [4390], 'well)': [4398], 'halt': [4401], 'Fur-mediated': [4403], 'andpchEFGHI': [4408], 'addressed': [4460], 'bottleneck': [4466], 'lies': [4467], 'leading': [4473], 'products.': [4476], 'Clearly,': [4477], 'classical': [4479], 'pattern,': [4480], 'here.': [4493], 'Instead,': [4494], 'propose': [4496], 'first,': [4502], 'non-allosteric': [4503], 'ICS,': [4505], 'determinant': [4509], 'controlling': [4510], 'II).': [4518], 'observation': [4521], 'made': [4524], 'filamentous': [4526], 'fungi': [4527], 'penicillin': [4529], 'dependent': [4533], 'δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine': [4541], 'synthetase': [4542], '(35Kennedy': [4543], 'Turner': [4545], '253:': [4551], '189-197Crossref': [4552], '(83)': [4555], 'Streptomyces': [4560], 'clavuligerusthe': [4561], 'cephalosporin': [4572], '(36Khetan': [4574], 'Malmberg': [4576], 'L.H.': [4577], 'Sherman': [4578], 'Hu': [4580], 'W.S.': [4581], 'Ann.': [4582], 'Y.': [4584, 5110], '782:': [4588], '17-24Crossref': [4589], '(12)': [4592], 'producing': [4600], 'compounds,': [4602], 'rarely': [4607], '(if': [4608], 'ever)': [4609], 'investigated.': [4611], 'context,': [4615], 'placed': [4620], 'thepchDCBA': [4623], 'operon,': [4624, 4797], 'encodes,': [4626], 'order,': [4629], 'salicylate-activating': [4631], '(22Quadri': [4633], 'L.E.': [4634, 5385], 'Keating': [4635, 5388], 'T.A.': [4636, 5389], '1999;': [4642, 5219], '38:': [4643], '14941-14954Crossref': [4644], '(119)': [4647], 'thioesterase': [4651], 'unknown': [4653], '(Ref.': [4702], 'study).': [4728], 'positively': [4735], 'controlled': [4736], 'PchR': [4739], 'negatively': [4764], 'Within': [4795], 'pchDC': [4802], 'tightly': [4807], 'coordinated': [4808], 'post-transcriptional': [4811], 'level': [4812], 'autoinducer': [4844], 'signals': [4848], 'regulatingpchA': [4857], 'expression.': [4858], 'affinity': [4861], '(Km': [4866], 'enables': [4870], 'draw': [4874], 'effectively': [4875], 'pool': [4879], 'competition': [4881], 'metabolism': [4888], 'PAO1/pME3395,': [4896], 'maximizing': [4897], 'measurable': [4905], 'maximal': [4919], 'does': [4922], 'seriously': [4924], 'deplete': [4925], 'resources.': [4928], 'Table': [4932], 'II': [4933], 'show': [4935, 5095], 'improves': [4943], 'especially': [4958], 'phase.': [4962], 'Similar': [4963], 'observations': [4964], 'recently': [4966], 'reported': [4968], '(37Audenaert': [4975], 'Pattery': [4977], 'Cornelis': 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'traveled': [5229], 'widely': [5230], 'world.': [5234], 'idea': [5236], 'supported': [5238], 'finding': [5241], 'irp-9': [5244], 'ybtS': [5246], 'genes,': [5247], 'required': [5250], 'yersiniabactin': [5252], 'part': [5255, 5285], 'mobile': [5257], 'pathogenicity': [5258, 5287], 'islands': [5259, 5288], '(42Brem': [5260], 'Pelludat': [5262], 'Rakin': [5264], 'Jacobi': [5266], 'Heesemann': [5268], '147:': [5272], '1115-1127Crossref': [5273], 'Other': [5279], 'such,': [5291], 'transmissible': [5293], 'different': [5295], 'bacteria.': [5296], 'speculated': [5300], 'MbtI': [5302], 'Mycobacterium': [5304], 'tuberculosis,': [5305], 'YbtS': [5306], 'Yersinia': [5308, 5551], 'pestis,': [5309], 'Irp-9': [5311, 5492], 'ofYersinia': [5312], 'enterocolitica,': [5313], 'peripheral': [5316], 'slightly': [5324], 'smaller': [5325], 'carry': [5330], 'direct': [5333], 'basically': [5339], 'organisms': [5343], 'homolog': [5346, 5581], 'vicinity': [5352], '(43Gehring': [5357], 'A.M.': [5358], 'DeMoll': 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[5572], 'thaliana,': [5573], 'PchA-like': [5576], '(40Wildermuth': [5585], 'thank': [5603], 'Rindisbacher': [5605], 'help': [5607], 'antibody': [5609], 'preparation': [5610], 'E.W.': [5612], 'isochorismate.': [5618]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2058780226', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2025-01-07T23:23:27.951695', 'created_date': '2016-06-24'}