Synergistic Lewis base and anion-binding catalysis for the enantioselective vinylogous addition of deconjugated butenolides to allenoates

Name: Work Video:
Duration: 3 min 30 s
Description: An enantioselective vinylogous umpolung addition of deconjugated butenolides to allenoates has been developed for the first time with the help of synergistic combination of an achiral phosphine and a chiral squaramide, and represents the first example of a catalytic enantioselective Cγ–Cγ bond formation between two different carbonyl partners.
Vikas Kumar; Santanu Mukherjee
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