Publication Information

{'id': 'https://openalex.org/W2058601709', 'doi': 'https://doi.org/10.1002/1439-7633(20010903)2:9<706::aid-cbic706>3.0.co;2-j', 'title': 'Studies on DNA Cleavage by Cytotoxic Pyrrole Alkaloids Reveal the Distinctly Different Behavior of Roseophilin and Prodigiosin Derivatives', 'display_name': 'Studies on DNA Cleavage by Cytotoxic Pyrrole Alkaloids Reveal the Distinctly Different Behavior of Roseophilin and Prodigiosin Derivatives', 'publication_year': 2001, 'publication_date': '2001-09-03', 'ids': {'openalex': 'https://openalex.org/W2058601709', 'doi': 'https://doi.org/10.1002/1439-7633(20010903)2:9<706::aid-cbic706>3.0.co;2-j', 'mag': '2058601709', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11828508'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1439-7633(20010903)2:9<706::aid-cbic706>3.0.co;2-j', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S154285657', 'display_name': 'ChemBioChem', 'issn_l': '1439-4227', 'issn': ['1439-4227', '1439-7633'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5054667122', 'display_name': 'Alois Fürstner', 'orcid': 'https://orcid.org/0000-0003-0098-3417'}, 'institutions': [{'id': 'https://openalex.org/I4210090782', 'display_name': 'Max-Planck-Institut für Kohlenforschung', 'ror': 'https://ror.org/00a7vgh58', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210090782']}, {'id': 'https://openalex.org/I149899117', 'display_name': 'Max Planck Society', 'ror': 'https://ror.org/01hhn8329', 'country_code': 'DE', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I149899117']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Alois Fürstner', 'raw_affiliation_strings': ['Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society'], 'affiliations': [{'raw_affiliation_string': 'Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society', 'institution_ids': ['https://openalex.org/I4210090782', 'https://openalex.org/I149899117']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5055115614', 'display_name': 'Eric Jarek Grabowski', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090782', 'display_name': 'Max-Planck-Institut für Kohlenforschung', 'ror': 'https://ror.org/00a7vgh58', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210090782']}, {'id': 'https://openalex.org/I149899117', 'display_name': 'Max Planck Society', 'ror': 'https://ror.org/01hhn8329', 'country_code': 'DE', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I149899117']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Eric Jarek Grabowski', 'raw_affiliation_strings': ['Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society'], 'affiliations': [{'raw_affiliation_string': 'Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society', 'institution_ids': ['https://openalex.org/I4210090782', 'https://openalex.org/I149899117']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.648, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 64, 'citation_normalized_percentile': {'value': 0.902651, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '2', 'issue': '9', 'first_page': '706', 'last_page': '709'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12673', 'display_name': 'Microbial Metabolism and Applications', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12673', 'display_name': 'Microbial Metabolism and Applications', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10252', 'display_name': 'Microbial Natural Products and Biosynthesis', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Natural Compounds', 'score': 0.9794, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cleavage', 'display_name': 'Cleavage (geology)', 'score': 0.6691476}, {'id': 'https://openalex.org/keywords/prodigiosin', 'display_name': 'Prodigiosin', 'score': 0.66187656}, {'id': 'https://openalex.org/keywords/pyrrole', 'display_name': 'Pyrrole', 'score': 0.41266838}], 'concepts': [{'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.74579346}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.6921145}, {'id': 'https://openalex.org/C175156509', 'wikidata': 'https://www.wikidata.org/wiki/Q1990218', 'display_name': 'Cleavage (geology)', 'level': 3, 'score': 0.6691476}, {'id': 'https://openalex.org/C2779337610', 'wikidata': 'https://www.wikidata.org/wiki/Q415663', 'display_name': 'Prodigiosin', 'level': 5, 'score': 0.66187656}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.6029676}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.53577214}, {'id': 'https://openalex.org/C2779400197', 'wikidata': 'https://www.wikidata.org/wiki/Q242627', 'display_name': 'Pyrrole', 'level': 2, 'score': 0.41266838}, {'id': 'https://openalex.org/C109316439', 'wikidata': 'https://www.wikidata.org/wiki/Q246181', 'display_name': 'Cytotoxicity', 'level': 3, 'score': 0.41013968}, {'id': 'https://openalex.org/C21951064', 'wikidata': 'https://www.wikidata.org/wiki/Q899212', 'display_name': 'Combinatorial chemistry', 'level': 1, 'score': 0.34313062}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.265068}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.17340353}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.14801183}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.14521843}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C43369102', 'wikidata': 'https://www.wikidata.org/wiki/Q2307625', 'display_name': 'Fracture (geology)', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2776309202', 'wikidata': 'https://www.wikidata.org/wiki/Q140004', 'display_name': 'Serratia marcescens', 'level': 4, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000470', 'descriptor_name': 'Alkaloids', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D006575', 'descriptor_name': 'Heterocyclic Compounds, 3-Ring', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011353', 'descriptor_name': 'Prodigiosin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011758', 'descriptor_name': 'Pyrroles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000470', 'descriptor_name': 'Alkaloids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000470', 'descriptor_name': 'Alkaloids', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004587', 'descriptor_name': 'Electrophoresis, Agar Gel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006575', 'descriptor_name': 'Heterocyclic Compounds, 3-Ring', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006575', 'descriptor_name': 'Heterocyclic Compounds, 3-Ring', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011353', 'descriptor_name': 'Prodigiosin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011353', 'descriptor_name': 'Prodigiosin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011758', 'descriptor_name': 'Pyrroles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011758', 'descriptor_name': 'Pyrroles', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1439-7633(20010903)2:9<706::aid-cbic706>3.0.co;2-j', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S154285657', 'display_name': 'ChemBioChem', 'issn_l': '1439-4227', 'issn': ['1439-4227', '1439-7633'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11828508', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4225000451', 'https://openalex.org/W3179131569', 'https://openalex.org/W3159145342', 'https://openalex.org/W2979842092', 'https://openalex.org/W2627006785', 'https://openalex.org/W2385741271', 'https://openalex.org/W2081937938', 'https://openalex.org/W2051442694', 'https://openalex.org/W1980788001', 'https://openalex.org/W1597713798'], 'abstract_inverted_index': {'Similar': [0], 'structure,': [1], 'same': [2], 'effect,': [3], 'different': [4], 'mechanism:': [5], 'The': [6], 'alkaloids': [7, 50], 'nonylprodigiosin': [8], '(1)': [9], 'and': [10, 17], 'roseophilin': [11], '(2)': [12], 'share': [13], 'several': [14], 'structural': [15], 'motifs': [16], 'are': [18], 'both': [19], 'highly': [20], 'cytotoxic.': [21], 'While': [22], 'the': [23, 33, 37], 'former': [24], 'induces': [25], 'effective': [26], 'strand': [27], 'cleavage': [28], 'of': [29, 35, 48, 58], 'supercoiled': [30], 'DNA': [31], 'in': [32], 'presence': [34], 'CuII,': [36], 'latter': [38], 'is': [39], 'totally': [40], 'inactive.': [41], 'A': [42], 'structure–activity': [43], 'profile': [44], 'for': [45], 'this': [46], 'class': [47], 'pyrrole': [49], 'has': [51], 'been': [52], 'established': [53], 'by': [54], 'testing': [55], 'various': [56], 'analogues': [57], 'these': [59], 'lead': [60], 'compounds.': [61]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2058601709', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-05T05:24:33.227890', 'created_date': '2016-06-24'}