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3834, 3917, 3924, 4071, 4108, 4119, 4133, 4136, 4242, 4274, 4332, 4377, 4383, 4393, 4500, 4515, 4518, 4561, 4574, 4721, 4735, 4839, 4841, 4888, 4979, 5052, 5063, 5112, 5119, 5217, 5283, 5285, 5307, 5362, 5379, 5386, 5404], 'glucocorticoid': [3, 36, 110, 129, 162, 236, 255, 592, 778, 4611], 'hormones': [4, 111, 130, 237, 256], 'elicit': [5, 131], 'divergent': [6, 132], 'often': [8, 134], 'opposing': [9, 103, 135, 229, 333, 707, 4557], 'effects': [10, 105, 136, 231, 259, 281, 334, 708, 732, 1191, 2908, 4389, 4558, 4630, 4659], 'in': [11, 79, 82, 137, 205, 208, 325, 507, 527, 615, 720, 804, 832, 861, 1051, 1162, 1171, 1213, 1224, 1474, 1509, 1596, 1610, 1666, 1715, 1822, 1847, 1879, 1930, 2076, 2242, 2356, 2373, 2518, 2593, 2618, 2681, 2772, 2880, 2901, 3006, 3154, 3188, 3277, 3328, 3336, 3394, 3426, 3437, 3448, 3450, 3499, 3508, 3596, 3614, 3633, 3663, 3773, 3937, 3969, 3993, 4184, 4257, 4293, 4372, 4507, 4513, 4516, 4567, 4618, 4651, 4678, 4681, 5068, 5073, 5122, 5369], 'cells,': [12, 138, 2376, 4172, 4186, 4509], 'tissues,': [13, 139, 4376], 'animals.': [15, 141], 'A': [16, 142, 3431, 4368], 'wide': [17, 143], 'range': [18, 144], 'of': [19, 106, 145, 232, 273, 293, 328, 709, 733, 800, 936, 1033, 1107, 1138, 1199, 1207, 1255, 1262, 1270, 1279, 1286, 1293, 1298, 1305, 1329, 1363, 1395, 1397, 1411, 1488, 1530, 1652, 1668, 1705, 1871, 1875, 1883, 2011, 2045, 2071, 2078, 2099, 2144, 2186, 2192, 2199, 2208, 2347, 2382, 2443, 2454, 2494, 2571, 2580, 2622, 2678, 2768, 2780, 2837, 2890, 2896, 2909, 2955, 3030, 3053, 3075, 3102, 3132, 3179, 3228, 3263, 3292, 3346, 3358, 3367, 3405, 3421, 3433, 3502, 3511, 3527, 3560, 3603, 3609, 3628, 3636, 3702, 3707, 3764, 3778, 3785, 3793, 3810, 3832, 3840, 3856, 3873, 3894, 3932, 3972, 3988, 4052, 4130, 4283, 4370, 4525, 4532, 4559, 4572, 4590, 4602, 4648, 4660, 4708, 4858, 4879, 5076, 5141, 5179, 5196, 5200, 5276, 5310, 5322, 5346], 'physiological': [20, 104, 146, 230, 5305], 'molecular': [22, 148, 1133], 'biological': [23, 149], 'evidence': [24, 100, 150, 226, 1047, 2945, 3166, 5083, 5106], 'suggests': [25, 151], 'that': [26, 29, 50, 63, 86, 101, 152, 155, 176, 189, 212, 227, 278, 922, 1036, 1113, 1183, 1698, 2448, 2458, 2508, 2829, 2872, 2947, 3114, 3147, 3563, 3587, 3626, 3723, 3784, 3831, 3849, 3881, 3893, 3915, 3929, 3980, 4024, 4049, 4189, 4271, 4310, 4318, 4330, 4381, 4396, 4498, 4510, 4519, 4542, 4555, 4626, 4641, 4701, 4716, 5032, 5044, 5084, 5107, 5115, 5137, 5208, 5219, 5268, 5326, 5342], 'the': [27, 33, 59, 98, 102, 107, 115, 123, 153, 159, 185, 224, 228, 233, 241, 249, 274, 290, 318, 482, 486, 591, 728, 949, 1136, 1143, 1193, 1244, 1315, 1326, 1345, 1422, 1468, 1475, 1492, 1586, 1602, 1614, 1621, 1638, 1669, 1699, 1792, 1795, 1844, 1887, 1931, 2005, 2016, 2029, 2057, 2061, 2069, 2079, 2082, 2100, 2167, 2172, 2271, 2279, 2293, 2379, 2424, 2492, 2589, 2596, 2756, 2906, 2910, 2952, 3026, 3047, 3061, 3079, 3085, 3103, 3145, 3162, 3224, 3255, 3290, 3339, 3343, 3355, 3412, 3418, 3464, 3469, 3475, 3487, 3500, 3509, 3528, 3565, 3575, 3607, 3610, 3629, 3634, 3703, 3720, 3724, 3750, 3761, 3765, 3776, 3799, 3841, 3847, 3850, 3861, 3867, 3882, 3906, 3927, 3930, 3933, 3952, 3967, 3970, 3984, 3994, 4025, 4032, 4050, 4053, 4128, 4148, 4174, 4178, 4280, 4319, 4328, 4550, 4556, 4586, 4591, 4594, 4598, 4603, 4606, 4627, 4638, 4657, 4714, 4862, 4868, 4880, 4941, 5030, 5037, 5056, 5060, 5074, 5085, 5099, 5134, 5138, 5142, 5153, 5223, 5273, 5277, 5304, 5320, 5339, 5343, 5347, 5401], 'receptors': [28, 37, 121, 154, 163, 247, 319, 520, 2295, 2425, 2590, 3119, 3197, 4175, 4321], 'mediate': [30, 156, 2877, 4387], 'these': [31, 157, 321, 329, 1108, 2581, 2873, 3583, 4538, 4702, 5201, 5311, 5336], 'effects,': [32, 158, 4728], '(AR': [38, 164], 'GR,': [40, 166, 1038, 2666, 3269, 3503], 'respectively),': [41, 167], 'influence': [42, 168, 2249, 4845], 'each': [43, 92, 169, 218, 1126, 1271, 2200, 2250, 3298, 4503, 4846], "other's": [44, 93, 170, 219, 1127, 2251, 4504, 4847], 'transcriptional': [45, 60, 124, 171, 186, 250, 291, 857, 1128, 1194, 2252, 2420, 2502, 2953, 3072, 3092, 3111, 3737, 3863, 3883, 3944, 4505, 4551, 4859, 5371], 'activity.': [46, 94, 172, 220, 1568, 3073, 5372], 'We': [47, 173, 1175, 2238, 2264, 2583, 2605, 3598, 4046, 4495, 4553, 5373, 5392], 'now': [48, 174], 'show': [49, 175], 'coexpressed': [51, 177, 3187], 'AR': [52, 178, 793, 931, 1114, 1263, 1400, 1616, 1640, 1700, 1838, 2002, 2020, 2046, 2145, 2153, 2193, 2245, 2287, 2316, 2409, 2435, 2498, 2521, 2547, 2562, 2891, 3042, 3168, 3180, 3258, 3330, 3406, 3488, 3491, 3538, 3561, 3566, 3588, 3759, 3788, 3828, 3916, 3989, 4027, 4137, 4197, 4273, 4333, 4382, 4499, 4530, 4573, 4633, 4665, 4684, 4720, 4734, 4840, 5051], 'GR': [54, 180, 795, 929, 944, 1058, 1116, 1256, 1398, 1737, 1836, 2106, 2110, 2147, 2155, 2187, 2247, 2289, 2301, 2372, 2416, 2428, 2437, 2501, 2523, 2539, 2549, 2564, 2617, 2769, 2844, 2893, 3044, 3170, 3182, 3260, 3382, 3408, 3466, 3476, 3512, 3590, 3640, 3794, 3833, 3897, 3918, 4135, 4243, 4275, 4331, 4384, 4501, 4533, 4575, 4642, 4722, 4736, 4842, 4980], 'indeed': [55, 181], 'do': [56, 89, 182, 215, 4322, 4710, 4723, 4843], 'interact': [57, 183, 1119, 2592], 'at': [58, 74, 122, 184, 200, 248, 717, 933, 1142, 1192, 1221, 1447, 1453, 1941, 1981, 2254, 2432, 2438, 2451, 2504, 2555, 2568, 2578, 3152, 3243, 3789, 3951, 4034, 4042, 4065, 4089, 4110, 4142, 4285, 4534, 4549, 4565, 4637, 4705, 4717, 4741, 5331], 'level': [61, 187, 719, 4287], 'this': [64, 190, 1150, 1653, 2830, 3099, 3157, 3742, 3938, 3955, 5045, 5177, 5220, 5390], 'interaction': [65, 118, 191, 244, 716, 1141, 2143, 2879, 3063, 3087, 3158, 4548, 5048, 5325], 'is': [66, 192, 2834, 3159, 3836, 3853, 3879, 3941, 3976, 4059, 4063, 4697, 4851, 4938, 5034, 5081, 5104, 5146, 5204, 5214, 5269], 'correlated': [67, 193, 611], 'with': [68, 194, 612, 1156, 1232, 1252, 1276, 1340, 1490, 1516, 1637, 1712, 1823, 1843, 1959, 2068, 2089, 2152, 2161, 2183, 2205, 2270, 2286, 2378, 2491, 3023, 3098, 3126, 3194, 3219, 3307, 3411, 3556, 3666, 3733, 3900, 4114, 4296, 4597, 4876], 'their': [69, 120, 195, 246, 280, 721, 805, 856, 1189, 2682, 3273, 3300, 3504, 4397, 4546, 5383], 'ability': [70, 196], 'to': [71, 114, 197, 240, 284, 503, 511, 595, 602, 714, 811, 848, 1053, 1124, 1181, 1324, 1331, 1344, 1421, 1440, 1467, 1528, 1576, 1580, 1948, 2034, 2226, 2231, 2256, 2262, 2371, 2463, 2586, 2610, 2770, 2904, 3059, 3113, 3338, 3523, 3712, 3748, 3818, 3866, 3942, 3947, 3959, 3966, 3978, 4138, 4289, 4314, 4569, 4614, 4645, 4699, 4933, 5036, 5050, 5055, 5133, 5148, 5157, 5185, 5194, 5206, 5211, 5314], 'form': [72, 198], 'heterodimers': [73, 199, 4676, 4930, 5066, 5120], 'a': [75, 201, 326, 797, 812, 817, 1132, 1178, 1364, 1417, 1634, 1661, 1777, 1880, 1949, 1996, 2072, 2342, 2418, 2441, 2506, 2513, 2569, 2675, 2758, 2777, 2835, 2959, 3311, 3316, 3384, 3452, 3807, 3973, 3981, 4043, 4090, 4111, 4143, 4258, 4286, 4619, 4654, 4690, 4706, 4743, 4781, 4855, 5123, 5266, 5323, 5332, 5365], 'common': [76, 202, 813], 'DNA': [77, 203, 286, 814, 926, 1330, 1811, 5154, 5355], 'site,': [78, 204], 'vitro': [80, 206, 1597], 'vivo.': [83, 209, 3172], 'Furthermore,': [84, 210, 2824, 3447, 4292, 5102], 'mutants': [85, 211, 2108, 2113, 3055, 3134, 3178, 3201, 3709, 3859, 3875, 4277, 4298, 4304, 4528, 5279], 'cannot': [87, 213], 'heterodimerize': [88, 214, 1059, 3151, 3591, 4512], 'not': [90, 216, 846, 2461, 2526, 3083, 3136, 3380, 3495, 3579, 3825, 3946, 4265, 4323, 4385, 4711, 4724, 4814, 4844, 5147], 'inhibit': [91, 217, 603, 726, 1125, 4502], 'These': [95, 221, 706, 3141, 3717, 3910, 4325], 'observations': [96, 222, 2381, 3718, 5042, 5312], 'provide': [97, 223, 2341], 'first': [99, 225], 'are': [112, 238, 610, 1808, 2259, 3392, 4400, 4563, 4635, 5192], 'due': [113, 239, 2462, 3522], 'direct': [116, 242, 1168, 2838, 4934, 5108, 5180], 'physical': [117, 243, 1169, 2839], 'between': [119, 245, 2614, 2841, 4977, 5182], 'level.': [125, 251, 1147, 1195, 4552], 'have': [257, 332, 2114, 4496, 4581, 4726], 'profound': [258], 'on': [260, 1401, 2413, 2529, 2532, 2913, 2957, 3078, 3645, 3669, 3814, 4056, 4181, 4390, 4593, 4605, 5152, 5389], 'metabolism,': [261], 'animal': [262], 'behavior,': [263], 'cellular': [265, 4391], 'proliferation.': [266, 517], 'They': [267], 'act': [268, 484, 589, 4334], 'through': [269, 485, 590, 1121, 2620, 3705, 3905, 3922, 4576], 'intracellular': [270], 'receptors,': [271, 2175, 2456, 3442], 'members': [272, 4878], 'nuclear': [275, 4863, 4881, 5038, 5061, 5100], 'receptor': [276, 488, 593, 777, 779, 786, 951, 1599, 2163, 2915, 3256, 3616, 3643, 3670, 3729, 3767, 3939, 3949, 4057, 4061, 4116, 4871, 4882, 5062, 5065, 5091, 5117, 5150, 5159, 5190, 5209, 5224, 5329, 5370], 'superfamily,': [277], 'exert': [279], 'by': [282, 852, 1243, 1407, 1585, 1659, 1703, 1820, 1830, 1977, 1985, 1994, 2056, 2066, 2150, 2266, 2365, 2764, 2775, 3116, 3323, 3371, 3497, 3525, 3574, 3731, 3798, 3838, 3886, 4031, 4191, 4195, 4523, 4632, 4664, 4674, 4861, 4940, 5354], 'binding': [283, 3302, 3337, 3368, 4117, 5210], 'specific': [285, 3375, 3454], 'sites': [287, 1807, 4118, 4120], 'modulating': [289], 'activity': [292, 932, 1582, 2233, 2338, 2361, 2412, 2431, 2503, 2543, 2916, 2954, 3016, 3035, 3093, 3112, 3644, 3711, 3730, 3763, 3777, 3792, 3813, 3864, 3884, 4039, 4058, 4062, 4129, 4141, 4685, 4740, 5275], 'linked': [294], 'genes': [295, 4649], '(for': [296], 'review': [297], 'see': [298, 3459, 5286], 'Ref.': [299, 2918, 4072, 5287], '1Truss': [300], 'M.': [301, 303, 357, 374, 378, 395, 444, 459, 555, 640, 670, 685, 755, 902, 1088, 1295, 1375, 2013, 2320, 2389, 2470, 4347, 4459, 4474, 5012, 5377, 5396], 'Beato': [302], 'Endocr.': [304], 'Rev.': [305], '1993;': [306, 891, 958, 982, 1552, 2307, 4010, 4249, 4966], '14:': [307], '459-479Crossref': [308], 'PubMed': [309, 349, 366, 387, 402, 419, 438, 453, 475, 547, 562, 581, 632, 647, 664, 679, 701, 749, 771, 877, 894, 915, 961, 985, 1008, 1078, 1100, 1388, 1555, 1692, 1769, 1920, 2136, 2310, 2333, 2402, 2483, 2645, 2701, 2723, 2750, 2799, 2821, 2863, 2937, 2983, 3693, 4013, 4162, 4219, 4239, 4252, 4363, 4417, 4434, 4453, 4468, 4490, 4758, 4771, 4806, 4836, 4903, 4923, 4951, 4969, 5002, 5024, 5241, 5261], 'Scopus': [310, 350, 367, 388, 403, 420, 439, 454, 476, 548, 563, 582, 633, 648, 665, 680, 702, 750, 772, 878, 895, 916, 962, 986, 1009, 1079, 1101, 1389, 1556, 1693, 1770, 2137, 2311, 2334, 2403, 2484, 2646, 2702, 2751, 2800, 2864, 2938, 2984, 3694, 4014, 4163, 4220, 4253, 4364, 4418, 4435, 4454, 4469, 4491, 4759, 4772, 4807, 4904, 4924, 4952, 4970, 5003, 5025, 5242, 5262], '(588)': [311], 'Google': [312, 352, 369, 390, 405, 422, 441, 456, 478, 550, 565, 584, 635, 650, 667, 682, 704, 752, 774, 880, 897, 918, 964, 988, 1011, 1026, 1081, 1103, 1391, 1558, 1695, 1772, 1921, 2139, 2313, 2336, 2405, 2486, 2648, 2663, 2704, 2724, 2753, 2802, 2822, 2866, 2940, 2986, 3001, 3661, 3696, 4016, 4086, 4106, 4165, 4222, 4240, 4255, 4366, 4420, 4437, 4456, 4471, 4493, 4761, 4774, 4809, 4837, 4906, 4926, 4954, 4972, 5005, 5027, 5174, 5244, 5264, 5301], 'Scholar).': [313, 479, 585, 705, 775, 842, 919, 1027, 1104, 1392, 1559, 1773, 2140, 2406, 2664, 2754, 2823, 2867, 3002, 4017, 4166, 4367, 4494, 4810, 4927, 4973, 5175, 5302], 'Several': [314], 'mammalian': [315, 1988], 'tissues': [316, 330], 'coexpress': [317], 'for': [320, 943, 1135, 1167, 1188, 1480, 1500, 1564, 1938, 2345, 2894, 3167, 3212, 3297, 3400, 3547, 3736, 4121, 4584, 4872, 5098, 5272, 5382, 5398], 'two': [322, 1034, 1507, 1531, 2294, 4320], 'hormones,': [323], 'number': [327], 'they': [331, 2258, 2574, 2600, 4511, 5317], '(2Monder': [335, 533, 618, 4403], 'C.': [336, 534, 619, 4404, 4786], 'Sakai': [337, 535, 620, 4405], 'R.R.': [338, 536, 621, 4406], 'Miroff': [339, 537, 622, 4407], 'Y.': [340, 538, 623, 4408], 'Blanchard': [341, 343, 539, 541, 624, 626, 4409, 4411], 'D.C.': [342, 540, 625, 4410], 'R.J.': [344, 465, 542, 627, 691, 761, 4412, 4480], 'Endocrinology.': [345, 398, 543, 558, 628, 643, 4413], '1994;': [346, 384, 544, 629, 1094, 4360, 4414, 5018], '134:': [347, 545, 630, 4415], '1193-1198Crossref': [348, 546, 631, 4416], '(121)': [351, 549, 634, 4419], 'Scholar,': [353, 370, 391, 406, 423, 442, 457, 551, 566, 636, 651, 668, 683, 753, 881, 898, 965, 989, 1012, 1082, 2649, 2705, 2725, 2803, 2987, 4223, 4421, 4438, 4457, 4472, 4907, 4955, 5006, 5245], '3Sjogren': [354], 'J.': [355, 372, 413, 432, 448, 575, 658, 674, 743, 827, 993, 1016, 1063, 1754, 1911, 2121, 2630, 2653, 2713, 2714, 2811, 2812, 2848, 2922, 2968, 2991, 3651, 3678, 4076, 4096, 4208, 4359, 4428, 4447, 4463, 4913, 4987, 5164, 5253, 5257, 5291], 'Li': [356], 'Bjorntorp': [358, 379], 'P.': [359, 380, 4355, 4798], 'Biochim.': [360, 381], 'Biophys.': [361, 382], 'Acta.': [362, 383], '1995;': [363, 874, 1005, 1075, 1766, 2133, 2642, 2860, 2934, 2980, 3690, 4236, 4833, 4897, 4917, 4999], '1244:': [364], '117-120Crossref': [365], '(33)': [368], '4Sjogren': [371], 'Weck': [373], 'Nilsson': [375], 'A.': [376, 427, 570, 738, 885, 911, 1004, 1074, 1384, 1765, 2132, 2329, 2398, 2479, 2641, 2709, 2807, 2859, 2933, 2979, 3689, 4004, 4199, 4229, 4349, 4442, 4826, 4998, 5237], 'Ottosson': [377], '1224:': [385], '17-21Crossref': [386], '(16)': [389], '5Dahlberg': [392, 552, 637], 'E.': [393, 461, 553, 638, 687, 757, 2729, 3278, 4476], 'Snochowski': [394, 554, 639], 'Gustafsson': [396, 556, 641, 2710, 2742, 2808, 5229], 'J.A.': [397, 557, 642, 2743, 5230], '1981;': [399, 559, 644], '108:': [400, 560, 645], '1431-1440Crossref': [401, 561, 646], '(74)': [404, 564, 649], '6Smith': [407, 652, 4422], 'R.G.': [408, 431, 574, 653, 742, 4423, 4446], 'Syms': [409, 654, 4424], 'A.J.': [410, 425, 568, 655, 736, 883, 900, 1373, 2318, 2387, 2468, 4425, 4440], 'Norris': [411, 428, 571, 656, 739, 4426, 4443], 'J.S.': [412, 429, 572, 657, 740, 4427, 4444], 'Steroid': [414, 433, 576, 659, 744, 4429, 4448], 'Biochem.': [415, 434, 577, 660, 745, 4430, 4449], '1984;': [416, 661, 4431], '20:': [417, 662, 4432], '277-281Crossref': [418, 663, 4433], '(44)': [421, 666, 4436], '7Syms': [424, 567, 4439], 'Nag': [426, 569, 737, 4441], 'Smith': [430, 573, 741, 4445], '1987;': [435, 578, 746, 4450], '28:': [436, 579, 747, 4451], '109-116Crossref': [437, 580, 748, 4452], '(24)': [440, 583, 751, 4455], '8Mayer': [443, 669, 4458], 'Rosen': [445, 466, 671, 692, 762, 4460, 4481], 'F.': [446, 467, 672, 693, 763, 977, 1092, 4000, 4461, 4482, 5016], 'Am.': [447, 673, 4462], 'Physiol.': [449, 675, 4464], '1975;': [450, 676, 4465], '229:': [451, 677, 4466], '1381-1386Crossref': [452, 678, 4467], '(87)': [455, 681, 4470], '9Mayer': [458, 684, 754, 4473], 'Shafrir': [460, 686, 756, 4475], 'Kaiser': [462, 688, 758, 4477], 'N.': [463, 689, 759, 4478], 'Milholland': [464, 690, 760, 4479], 'Metabolism.': [468, 694, 764, 4483], '1976;': [469, 695, 765, 4484], '25:': [470, 696, 766, 4485], '157-167Abstract': [471, 697, 767, 4486], 'Full': [472, 698, 768, 1097, 1917, 2720, 2818, 4214, 4216, 4487, 4803, 4900, 4920, 5021], 'Text': [473, 699, 769, 1098, 1918, 2721, 2819, 4215, 4217, 4488, 4804, 4901, 4921, 5022], 'PDF': [474, 700, 770, 1099, 1919, 2722, 2820, 4218, 4489, 4805, 4902, 4922, 5023], '(43)': [477, 703, 773, 4492], 'For': [480, 1595, 2171, 4124, 4608], 'example,': [481, 4125, 4609], 'androgens': [483, 710, 734, 4560, 4592, 4661], '(AR)': [489], '1The': [490], 'abbreviations': [491], 'used': [492, 1177, 1321, 2606, 2886], 'are:ARandrogen': [493], 'receptorGRglucocorticoid': [494], 'receptorDBDDNA-binding': [495], 'domainHREhormone': [496], 'response': [497, 783, 819, 2421], 'elementMRmineralocorticoid': [498], 'receptorCATchloramphenicol': [499], 'acetyltransferaseHAhemagglutininPCRpolymerase': [500], 'chain': [501, 791], 'reaction': [502, 792, 1848, 1932, 1944, 3438], 'stimulate': [504], 'protein': [505, 599, 1577, 1636, 1655, 1739, 2228, 3332, 3422, 5360], 'synthesis': [506], 'skeletal': [508, 597], 'muscle': [509, 514, 598, 605], 'increase': [512], 'smooth': [513, 604], 'prostate': [516, 607], 'Additionally,': [518], 'may': [521, 5053], 'be': [522, 849, 3057, 3521, 3572, 3819, 4672, 4694, 5315, 5352], 'involved': [523, 4650], 'directly': [524, 1120, 3242, 3592], 'or': [525, 1267, 1837, 1893, 2091, 2196, 2292, 2351, 2465, 2961, 3090, 3198, 3315, 3639, 4302, 4729, 4780, 5359], 'indirectly': [526], 'triggering': [528], 'aggressive': [529], 'dominant': [530], 'male': [531, 616], 'behavior': [532, 614], 'In': [586, 1105, 2407, 2440, 3096, 3806, 4018, 4167, 4653, 5198], 'contrast,': [587, 2408], 'glucocorticoids': [588, 712, 725, 4562, 4604], '(GR)': [594], 'cause': [596], 'degradation': [600], 'proliferation': [608, 4394], 'submissive': [613], 'rats': [617], 'appear': [713, 847], 'reflect': [715], 'some': [718, 862], 'signaling': [722, 4398], 'pathways': [723, 4399], 'since': [724, 855], 'both': [727, 2227, 2260, 3009, 3441, 3564, 4196, 4272, 4737], 'proliferative': [729], 'anabolic': [731, 4629], '(7Syms': [735], 'DNA-binding': [780, 806, 1839, 3549], 'domain': [781, 5267], 'hormone': [782, 818], 'element': [784, 820], 'mineralocorticoid': [785, 950], 'chloramphenicol': [787, 1367], 'acetyltransferase': [788, 1368], 'hemagglutinin': [789, 1649], 'polymerase': [790], 'display': [796], 'high': [798, 2676], 'degree': [799, 2677], 'sequence': [801, 1341, 1639, 1664, 2679], 'homology,': [802], 'particularly': [803], 'domains': [807, 1604, 1840], '(DBDs),': [808], 'bind': [810, 1041, 4931, 5121], 'site': [815, 2075, 3314, 3319, 4784, 5178], 'termed': [816], '(HRE)': [821], '(10Pearce': [822], 'D.': [823, 825, 954, 971, 997, 1020, 1067, 1548, 1758, 2125, 2303, 2634, 2657, 2852, 2926, 2972, 2995, 3655, 3682, 4080, 4100, 4245, 4991, 5168, 5295], 'Schlondorff': [824], 'Bonventre': [826], 'Molecular': [828], 'Nephrology:': [829], 'Kidney': [830], 'Function': [831], 'Health': [833], 'Disease.': [835], 'Marcel': [836], 'Dekker,': [837], 'Inc.,': [838], 'New': [839], 'York1995:': [840], '525-533Google': [841], 'Receptor': [843], 'specificity': [844], 'does': [845, 4813, 5097], 'determined': [850, 1406, 2149, 4939], 'primarily': [851, 4932], 'protein-DNA': [853], 'interaction,': [854], 'activities': [858, 2253, 2524, 2565, 3221, 3303, 4506], 'differ': [859, 2566, 5067], 'markedly': [860, 2567, 3641], 'contexts': [863], '(Fig.1': [864], 'Refs.': [866], '11Rundlett': [867], 'S.E.': [868, 3227], 'Miesfeld': [869], 'R.L.': [870], 'Mol.': [871, 888, 980, 1021, 2658, 2996, 3656, 4007, 4081, 4101, 4234, 4831, 5169, 5296], 'Cell.': [872, 889, 4008, 4799, 4896, 4916], 'Endocrinol.': [873, 981, 1022, 2659, 2997, 3657, 4082, 4102, 4235, 4832, 5170, 5297], '109:': [875], '1-10Crossref': [876], '(52)': [879], '12Adler': [882], 'Scheller': [884], 'Robins': [886, 903, 1376, 2321, 2390, 2471, 5378, 5397], 'D.M.': [887, 904, 1377, 2322, 2391, 2472], 'Biol.': [890, 1912, 2715, 2813, 4009, 4209], '13:': [892, 1095, 4011, 4361, 5019], '6326-6335Crossref': [893], '(93)': [896], '13Adler': [899], 'Danielsen': [901, 1374, 2319, 2388, 2469], 'Proc.': [905, 998, 1068, 1378, 1759, 2126, 2323, 2392, 2473, 2635, 2853, 2927, 2973, 3683, 4992, 5231], 'Natl.': [906, 999, 1069, 1379, 1760, 2127, 2324, 2393, 2474, 2636, 2854, 2928, 2974, 3684, 4993, 5232], 'Acad.': [907, 1000, 1070, 1380, 1761, 2128, 2325, 2394, 2475, 2637, 2855, 2929, 2975, 3685, 4994, 5233], 'Sci.': [908, 1001, 1071, 1381, 1762, 2129, 2326, 2395, 2476, 2638, 2856, 2930, 2976, 3686, 4995, 5234], 'U.': [909, 1002, 1072, 1382, 1763, 2130, 2327, 2396, 2477, 2639, 2857, 2931, 2977, 3687, 4996, 5235, 5249], 'S.': [910, 1003, 1073, 1383, 1764, 2131, 2328, 2397, 2478, 2640, 2858, 2932, 2978, 3688, 4345, 4794, 4997, 5236], '1992;': [912, 1385, 2330, 2399, 2480], '89:': [913, 1386, 2331, 2400, 2481], '11660-11663Crossref': [914, 1387, 2332, 2401, 2482], '(132)': [917, 1390, 2335, 2404, 2485], 'It': [920, 3878, 3975, 4696], 'appears': [921, 3436, 3958, 5114, 5184], 'factors': [923, 5361], 'other': [924, 3080, 3548, 3968, 4718], 'than': [925, 2544, 2554, 3017, 3036, 3783, 3821, 3892, 4667], 'affinity': [927], 'control': [928], 'different': [934], 'types': [935], 'HREs,': [937, 2572], 'as': [938, 1042, 1247, 1310, 1322, 1544, 1633, 1674, 1749, 2038, 2179, 2527, 2531, 2671, 2882, 3004, 3038, 3202, 3424, 3543, 3803, 4183, 4261, 4335, 4341, 4610, 4854, 5095], 'has': [939, 1048, 2826, 3544, 3618, 3990, 4981], 'been': [940, 2097, 2115, 2827, 3545, 3991, 4982], 'described': [941, 1248, 1545, 1675, 1750, 2039, 2116, 2169, 2180, 3546, 4983], 'previously': [942, 1546, 2117, 4263, 4343], 'its': [946, 3387, 3667, 3734, 4038], 'close': [947], 'relative,': [948], '(MR)': [952], '(14Pearce': [953, 1547, 2302, 4244], 'Yamamoto': [955, 1549, 1686, 2304, 2693, 2740, 2791, 4156, 4246, 4752], 'K.R.': [956, 1550, 1687, 2305, 2694, 2741, 2792, 4157, 4247, 4753], 'Science.': [957, 1551, 2306, 2746, 4158, 4248, 4754, 4947], '259:': [959, 1553, 2308, 4250], '1161-1165Crossref': [960, 1554, 2309, 4251], '(399)': [963, 1557, 2312, 4254], '15Rupprecht': [966], 'R.': [967, 1086, 1683, 2731, 2745, 5010], 'Arriza': [968], 'J.L.': [969], 'Spengler': [970], 'Reul': [972, 1089, 5013], 'J.M.': [973, 1090, 5014], 'Evans': [974, 4894, 4914, 4962], 'R.M.': [975, 4895, 4915, 4946, 4963], 'Holsboer': [976, 1091, 5015], 'Damm': [978], 'K.': [979, 2707, 2735, 2805, 4911, 4961], '7:': [983, 4967], '597-603Crossref': [984], '(120)': [987], '16Liu': [990, 2919, 3675], 'W.-H.': [991, 1014, 1061, 1752, 2119, 2628, 2651, 2846, 2920, 2966, 2989, 3649, 3676, 4074, 4094, 4985, 5162, 5289], 'Wang': [992, 1015, 1062, 1753, 2120, 2629, 2652, 2847, 2921, 2967, 2990, 3650, 3677, 4075, 4095, 4986, 5163, 5290], 'Sauter': [994, 1064, 1755, 2122, 2631, 2849, 2923, 2969, 3679, 4988], 'N.K.': [995, 1065, 1756, 2123, 2632, 2850, 2924, 2970, 3680, 4989], 'Pearce': [996, 1019, 1066, 1757, 2124, 2633, 2656, 2851, 2925, 2971, 2994, 3654, 3681, 4079, 4099, 4990, 5167, 5294], '92:': [1006, 1076, 1767, 2134, 2643, 2861, 2935, 2981, 3691, 5000], '12480-12484Crossref': [1007, 1077, 1768, 2135, 2644, 2862, 2936, 2982, 3692, 5001], '(205)': [1010, 1080, 1771, 2138, 2647, 2865, 2939, 2985, 3695, 5004], '17Liu': [1013, 2650, 2988, 4073, 5288], 'Yu': [1017, 2654, 2992, 3652, 4077, 4097, 5165, 5292], 'G.-Q.': [1018, 2655, 2993, 3653, 4078, 4098, 5166, 5293], '1996;': [1023, 2660, 2998, 3658, 4083, 4103, 4211, 5171, 5298], '10:': [1024, 2661, 2999, 3659, 4084, 4104, 5172, 5299], '1399-1406PubMed': [1025, 2662, 3000, 3660, 4085, 4105, 5173, 5300], 'HREs': [1028, 1161, 1403, 2255, 2511, 3647, 4036, 4068, 4709, 4719, 5213], 'contain': [1029], 'imperfect': [1030], 'palindromes': [1031], 'composed': [1032], 'half-sites': [1035, 3321], 'AR,': [1037, 2366, 2665, 3749], 'MR': [1040, 1056, 2615, 2668, 2842, 3638, 4978], 'head-to-head': [1043, 5124], 'homodimers,': [1044], 'recent': [1046], 'suggested': [1049, 3719, 4342], 'that,': [1050], 'addition': [1052, 1704], 'homodimer': [1054, 2773, 3361, 3390, 3467, 3489, 3539, 3567], 'formation,': [1055, 3067, 3245, 3402], '(16Liu': [1060, 1751, 2118, 2627, 2845, 2965, 4984], '18Trapp': [1083, 5007], 'T.': [1084, 2727, 4957, 5008], 'Rupprecht': [1085, 5009], 'Castren': [1087, 5011], 'Neuron.': [1093, 5017], '1457-1462Abstract': [1096, 5020], '(264)': [1102, 5026], 'view': [1106], 'observations,': [1109, 5079, 5202], 'it': [1110, 2459, 2825, 2869, 5096, 5113, 5203], 'seemed': [1111, 2870], 'plausible': [1112], 'might': [1117, 3520, 4580, 4671, 4693, 5351], 'also': [1118, 1176, 1405, 1657, 2224, 2499, 3796, 4047, 4269, 4670, 5129, 5270], 'heterodimer': [1122, 1184, 2612, 3066, 3244, 3401, 3445, 3472, 3530, 3533, 3570, 3601, 4521, 4543, 4577, 4622, 4975], 'formation': [1123, 1185, 2493, 2613, 2774, 3534, 3602, 4522, 4544, 4623, 4850, 4976], 'activities,': [1129], 'thus': [1130, 3536, 5363], 'providing': [1131, 5399], 'basis': [1134, 5309], 'observation': [1137], 'an': [1139, 1311, 1485, 1831, 1894, 2495, 2607, 3557, 3901, 4816], 'inhibitory': [1140, 1190, 2496, 3902, 3961, 4402, 4547, 4703, 5187, 5344], 'cell': [1144], 'tissue': [1146], 'To': [1148, 3240, 3287, 3398, 3739], 'examine': [1149, 3740], 'possibility,': [1151], 'we': [1152, 2446, 2885, 3246, 3585, 4126, 4187, 4268, 4308], 'performed': [1153, 3247], 'co-transfection': [1154], 'experiments': [1155, 3449, 4169, 4295], 'various': [1157, 3403], 'AR-specific': [1158], 'GR-specific': [1160], 'cultured': [1163, 4378, 4508], 'cells': [1164, 1202, 1497, 1537, 2176, 2269, 2298, 4379, 4514], 'tested': [1166, 3600, 4127], 'interactions': [1170, 4704], 'gel': [1172, 1953, 3248, 3356], 'shift': [1173, 1834, 3249], 'assays.': [1174], 'genetic': [1179], 'approach': [1180, 2608], 'demonstrate': [1182, 2575, 2611], 'was': [1186, 1308, 1320, 1404, 1456, 1494, 1656, 1673, 1701, 1745, 1818, 1828, 1928, 1992, 2026, 2064, 2148, 2362, 2460, 2489, 2762, 3192, 3333, 3369, 3462, 3506, 3755, 3769, 3780, 3795, 3816, 3890, 4028, 4040, 4193, 4312], 'essential': [1187], '60–80%': [1196], 'confluent': [1197], 'monolayers': [1198], 'monkey': [1200], 'CV-1b': [1201, 2268, 2297, 2375, 3189, 4185], '(Cell': [1203], 'Culture': [1204], 'Facility,': [1205], 'University': [1206, 1297], 'California,': [1208], 'San': [1209], 'Francisco)': [1210], 'were': [1211, 1241, 1464, 1472, 1498, 1504, 1526, 1538, 1542, 1562, 1574, 1608, 1618, 1789, 1813, 1841, 1946, 2054, 2086, 2159, 2177, 2219, 2223, 2239, 2426, 2525, 3186, 3210, 3217, 3275, 3281, 3304, 3409, 3479, 3494, 3554], 'grown': [1212], '5%': [1214, 1233, 1435], 'CO2,': [1215], '95%': [1216], 'air': [1217], '(relative': [1218], 'humidity,': [1219], '90%)': [1220], '37': [1222, 1510], '°C': [1223, 1511], "Dulbecco's": [1225], 'modified': [1226], "Eagle's": [1227], 'medium': [1228, 1433, 1476, 1489], 'H-16': [1229], '(Mediatech)': [1230], 'supplemented': [1231], 'fetal': [1234], 'calf': [1235], 'serum': [1236, 1437, 1493, 1877], '(Life': [1237, 1249], 'Technologies,': [1238, 1250], 'Inc.).': [1239], 'Cells': [1240, 1471, 1503, 2158], 'transfected': [1242, 2160, 2178, 2348, 2374, 2455], 'LipofectAMINE': [1245], 'method': [1246], 'Inc.),': [1251], '100': [1253, 1260, 1268, 1284, 1448, 1454, 1873, 3204], 'ng': [1254, 1261, 1269, 1278, 1285, 1304, 1410, 1870, 1874, 2185, 2191, 2198, 2207], 'expression': [1257, 1264, 1272, 1989, 2164, 2188, 2194, 2201, 2346], 'plasmid': [1258, 1265, 1273, 1281, 1288, 1307, 1319, 1413, 1622, 2030, 2093, 2202, 2210], '(6RGR),': [1259], '(6RAR),': [1266], 'together,': [1274, 2203, 4537], 'along': [1275, 2204], '50': [1277, 1409, 1731, 1733, 2206], 'reporter': [1280, 1287, 1335, 1356, 1370, 1412, 2209, 2360, 2507, 2963], 'TAT1-TATA': [1282, 1336, 2282, 2414, 3815], 'C′Δ9': [1289, 1357, 2274, 2359, 2433, 5403], '(a': [1290, 2008], 'kind': [1291], 'gift': [1292, 2010], 'Diane': [1294, 2012, 5376, 5395], 'Robins,': [1296], 'Michigan,': [1299], 'Ann': [1300], 'Arbor,': [1301], 'MI).': [1302], '20': [1303, 1853, 1884, 2184, 2190], 'RSV-β-gal': [1306], 'included': [1309, 1929], 'internal': [1312], 'standard,': [1313], 'BlueScript': [1316], 'KS−': [1317], 'vector': [1318, 1990, 2006, 2017], 'carrier': [1323], 'bring': [1325], 'total': [1327, 1881, 3419], 'amount': [1328, 3420], '1': [1332, 1858, 1866, 1970], 'μg.': [1333], 'contains': [1337, 1358, 1416, 2509], 'one': [1338, 1529, 1784, 3964, 4595], 'HRE': [1339, 1419, 1779, 1786, 1796, 1846, 2273, 2281, 3301, 3313, 3318, 3353, 3415, 4092, 4113], 'TGTACAGGATGTTCT': [1342], 'fused': [1343, 1420], 'Drosophila': [1346, 1424], 'alcohol': [1347, 1425], 'dehydrogenase': [1348, 1426], 'minimal': [1349, 1427, 2514], 'promoter': [1350, 1428], '(−33/+4)': [1351], 'driving': [1352, 1429, 2512], 'luciferase': [1353, 1430, 1565, 1570, 2284], 'expression.': [1354, 1431], 'Slp': [1359], 'enhancer': [1360], 'sequences': [1361], 'upstream': [1362], 'thymidine': [1365], 'kinase': [1366], '(CAT)': [1369], 'gene': [1371, 2964], '(13Adler': [1372, 2317, 2386, 2467], 'effect': [1394, 3668, 3903, 4051, 4692, 5345], 'cotransfection': [1396, 2151, 3101, 4168, 4294], 'multimerized': [1402, 3646], 'using': [1408, 2032, 3046, 3348, 3373], 'TAT3-TATA,': [1414, 2505], 'which': [1415, 1484, 2095, 2257, 3451], 'trimerized': [1418], 'same': [1423, 2597, 2831, 2874, 3048, 3743, 4179, 4639], 'Fresh': [1432], 'containing': [1434, 1477, 3272, 3309, 3440, 4146], 'stripped': [1436], '(charcoal': [1438], 'treated': [1439], 'remove': [1441], 'endogenous': [1442, 2300], 'steroids)': [1443], 'penicillin': [1445], 'G': [1446], 'units/ml': [1449], 'streptomycin': [1451], 'sulfate': [1452, 1708], 'μg/ml': [1455], 'added': [1457, 1495, 1527, 3211], '18': [1458], 'h': [1459, 1535], 'before': [1460], 'transfection.': [1461], 'Lipid-DNA': [1462], 'complexes': [1463, 1479], 'prepared': [1465, 1543], 'according': [1466], "manufacturer's": [1469], 'manual.': [1470], 'incubated': [1473, 1499], 'DNA-lipid': [1478], '5': [1481, 1728, 3396, 3516, 4070], 'h,': [1482], 'after': [1483], 'equal': [1486], 'volume': [1487, 1882], 'twice': [1491], '16': [1501], 'h.': [1502, 3214], 'then': [1505, 1710, 2087, 3051], 'washed': [1506], 'times': [1508], 'phosphate-buffered': [1512], 'saline,': [1513], 'refed': [1515], 'fresh': [1517], 'medium.': [1518], 'Corticosterone': [1519, 2212], '(100': [1520, 1524, 2213], 'nm)': [1521, 1525, 2214, 2218], 'dihydrotestosterone': [1523, 2216, 3209], 'identical': [1532], 'transfections;': [1533], '24': [1534, 3213], 'later,': [1536], 'harvested': [1539], 'extracts': [1541, 1561], 'assayed': [1563], 'CAT': [1567, 1572, 2276], 'Both': [1569], 'values': [1573, 2222, 3216], 'normalized': [1575, 2225, 3218], 'content': [1578, 2229], 'β-galactosidase': [1581, 2232, 3220], '(expression': [1583], 'driven': [1584], 'Rous': [1587], 'sarcoma': [1588], 'virus': [1589], 'promoter)': [1590], 'without': [1591, 2234], 'any': [1592, 2235], 'significant': [1593, 2236], 'difference.': [1594, 2237], 'measurements,': [1598], 'DBDs': [1600, 3274], 'lacking': [1601], 'ligand-binding': [1603], 'N': [1606, 5225], 'termini': [1607], 'expressed': [1609, 1626, 1746, 3276, 4870], 'bacteria.': [1611], 'Sequences': [1612], 'encoding': [1613], 'rat': [1615, 2001], 'DBD': [1617, 1670, 2062, 2080, 2104, 2683, 3163, 3331, 3562, 3594, 3611, 3630, 3725, 3842, 3907, 3934, 3985, 4818, 4942, 5086, 5143, 5348], 'cloned': [1619], 'into': [1620, 2015, 2028, 3620, 3757, 4170], 'pET-14b': [1623], '(Novagen)': [1624], 'inEscherichia': [1627], 'coli': [1628, 3279], 'strain': [1629], 'BL21': [1630], '(DE3)': [1631], 'pLysS': [1632], 'recombinant': [1635, 1654, 1738], 'residues': [1641, 2875], '535–623': [1642], '(89': [1643], 'residues,': [1644], '11.0': [1645], 'kDa).': [1646], 'An': [1647], 'influenza': [1648], '(HA)/epitope-tagged': [1650], 'version': [1651], 'obtained': [1658, 2055, 2065, 3115, 3555], 'introducing': [1660], 'three': [1662, 2510, 3229, 3324], 'HA-epitope': [1663], 'fragment': [1665, 2003], 'front': [1667, 2077], 'region.': [1671], 'Purification': [1672], '(19Freedman': [1676], 'L.P.': [1677, 1900, 2692, 2737, 2790], 'Luisi': [1678], 'B.F.': [1679, 2686, 2784], 'Korszun': [1680], 'Z.R.': [1681], 'Basavappa': [1682], 'Sigler': [1684, 2695, 2793], 'P.B.': [1685, 2696, 2794], 'Nature.': [1688, 2697, 2795], '1988;': [1689, 4948], '334:': [1690], '543-546Crossref': [1691], '(349)': [1694], 'Scholar),': [1696, 1922, 2487, 4087, 4107, 5028, 5265], 'except': [1697, 2182], 'precipitated': [1702], '45%': [1706], 'ammonium': [1707], 'redissolved': [1711], 'dialyzed': [1714], 'HEGDZ50': [1716], '(20': [1717], 'mm': [1718, 1723, 1729, 1734, 1851, 1854, 1859, 1867, 1964, 1967, 1971], 'Hepes,': [1719], 'pH': [1720, 1856, 1973], '7.5,': [1721], '0.5': [1722, 1960], 'EDTA,': [1724, 1860, 1972], '10%': [1725, 1861], '(v/v)': [1726], 'glycerol,': [1727, 1862], 'dithiothreitol,': [1730, 1868], 'μmZnSO4,': [1732], 'NaCl).': [1735], 'Rat': [1736], 'T7X556': [1740], '(179': [1741], 'residues;': [1742], '19.0': [1743], 'kDa)': [1744, 3271], 'purified': [1748, 3283], 'TAT0.5': [1775, 1798], '(containing': [1776, 1783], 'single': [1778, 3349, 3413, 4091], 'half-site)': [1780], 'TAT1.0': [1782, 1801], 'full': [1785, 1806, 3352], 'site)': [1787], 'probes': [1788], 'excised': [1790], 'from': [1791, 2004, 3582, 3963], 'plasmids': [1793, 2165, 5402], 'possessing': [1794], 'sequences:': [1797], '(TATCACGGATGTTCT)': [1799], '(TGTACAGGATGTTCT)': [1802], '(the': [1803], 'half-': [1804], 'underlined).': [1809], 'fragments': [1812, 2085], 'gel-purified': [1814], 'ethanol-precipitated.': [1816], 'Probe': [1817], '32P-end-labeled': [1819], 'filling': [1821], 'Klenow': [1824], '(Boehringer': [1825], 'Mannheim).': [1826], 'Binding': [1827], 'quantified': [1829], 'electrophoretic': [1832], 'mobility': [1833, 3345], 'assay.': [1835], 'mixed': [1842, 3410], '32P-labeled': [1845], 'buffer': [1849], '(50': [1850], 'NaCl,': [1852], 'Tris·HCl,': [1855, 1965], '7.9,': [1857], '0.1%': [1863], 'Nonidet': [1864], 'P-40,': [1865], '200': [1869], 'poly(dI-dC),': [1872], 'bovine': [1876], 'albumin)': [1878], 'μl.': [1885], 'Either': [1886], 'anti-HA': [1888, 3576], '(influenza': [1889], 'hemagglutinin)': [1890], 'monoclonal': [1891, 1896, 3455], 'antibody': [1892, 3457, 3577], 'anti-GR': [1895, 3456], 'antibody,': [1897], 'BuGR': [1898, 3498, 3526], '(20Eisen': [1899], 'Reichman': [1901], 'M.E.': [1902], 'Thompson': [1903], 'E.B.': [1904], 'Gametchu': [1905], 'B.': [1906], 'Harrison': [1907], 'R.W.': [1908], 'Eisen': [1909], 'H.J.': [1910, 4353, 4788], 'Chem.': [1913, 2716, 2814, 4210], '1985;': [1914], '260:': [1915], '11805-11810Abstract': [1916], 'directed': [1923], 'against': [1924], 'amino': [1925], 'acids': [1926], '407–420,': [1927], 'mixtures': [1933, 1945, 3439], 'where': [1934, 2599, 5189], 'indicated.': [1935], 'After': [1936], 'incubation': [1937], '15': [1939], 'min': [1940], 'room': [1942, 1982], 'temperature,': [1943, 1983], 'applied': [1947, 3747], '8.5%': [1950], 'nondenaturing': [1951], 'polyacrylamide': [1952], '(37.5:1,': [1954], 'acrylamide/bisacrylamide;': [1955], 'National': [1956], 'Diagnostics)': [1957], 'buffered': [1958], '×': [1961], 'TBE': [1962], '(44.5': [1963], '44.5': [1966], 'boric': [1968], 'acid,': [1969, 4874, 4886], '8),': [1974], 'resolved': [1976], 'electrophoresis': [1978], '(250': [1979], 'V)': [1980], 'followed': [1984], 'autoradiography.': [1986], '6RAR': [1991, 2031, 2090], 'made': [1993], 'inserting': [1995], '2.8-kilobase': [1997], 'pairXba': [1998], 'I-Xba': [1999], 'I': [2000], 'pCMV5': [2007], 'generous': [2009], 'Robins)': [2014], '6R.': [2018], 'point': [2021, 2107, 2836, 2897], 'mutation': [2022, 3754, 3982, 4033], '(Arg-581': [2023], '→': [2024, 3752], 'Asp)': [2025], 'introduced': [2027, 3756], 'PCR': [2033, 2067, 2084], 'generate': [2035], 'AR/R581D': [2036, 2051, 3779, 3812, 3887], 'mutant': [2037, 2052, 2352, 3029, 3766, 4026, 4134], 'previously.': [2040, 3805], 'N-terminal': [2042, 2102, 2111, 2173, 2887, 3183, 3671], 'deletion': [2043, 2112, 2174, 2888, 3184, 3672], 'derivatives': [2044, 2889, 3185, 3673], 'wild': [2047, 2349, 3018, 3070, 3117, 3195, 3714, 3786, 3822, 3868, 3895, 4131, 4290, 4315], 'type': [2048, 2350, 3019, 3071, 3118, 3196, 3715, 3787, 3823, 3869, 3896, 4132], '(ARΔN)': [2049], '(ARΔN/R581D)': [2053], 'following': [2058, 2166], 'steps.': [2059], 'First,': [2060], 'region': [2063], 'introduction': [2070, 2621, 2895], 'Bgl': [2073], 'II': [2074], 'region;': [2081], 'resulting': [2083, 4677, 4929], 'religated': [2088], '6RAR/R581D': [2092], 'fragments,': [2094], 'had': [2096, 2410, 2540, 2601, 3013, 3033], 'deleted': [2098], 'entire': [2101, 5057], 'regions.': [2105], 'Thein': [2141], 'vivo': [2142, 2594, 2619, 2881, 3155], 'complementary': [2156, 2623, 3054, 3104, 3708, 3857, 4297, 4526], 'mutants.': [2157], 'full-length': [2162, 2914, 3604, 3637, 3758], 'procedures': [2168], 'above.': [2170], 'above': [2181], 'plasmid,': [2189, 2195], '10': [2197], 'TAT3-TATA.': [2211, 3024, 3790, 4535], '(1000': [2217], 'used.': [2220], 'Luciferase': [2221, 3215], 'initially': [2240, 3305], 'interested': [2241], 'asking': [2243], 'if': [2244, 3741], 'could': [2248, 3571, 4278], 'able': [2261, 3058], 'bind.': [2263], 'began': [2265], 'transfecting': [2267], 'androgen-specific': [2272], '(driving': [2275, 2283], 'expression)': [2277, 2285], 'GR-responsive': [2280], 'either': [2290, 2958, 3310, 4742], 'alone': [2291, 3898], 'together.': [2296], 'lack': [2299], 'Scholar)': [2314, 2337, 3662, 4241, 4256, 4775, 4838], 'therefore': [2340], 'null': [2343], 'background': [2344], 'receptors.': [2353, 3605, 4864, 5039, 5101], 'As': [2354, 2516, 3326, 3771], 'shown': [2355, 2517, 2763, 2900, 3005, 3327, 3393, 3425, 3772, 3804], 'Fig.': [2357, 2519, 2902, 3007, 3427, 3699, 3774, 5281], '1A,': [2358], 'strongly': [2363, 3143, 3443, 4540], 'induced': [2364, 2417], 'but': [2367, 4395, 5155], 'responded': [2368], 'only': [2369, 4386], 'marginally': [2370], 'consistent': [2377, 2490, 3899], 'prior': [2380], 'Adler': [2383], 'et': [2384, 3623], 'al.': [2385, 3624, 4022], 'marginal': [2411], 'while': [2415, 2434, 3130, 3871, 4037, 4173], 'robust': [2419], '(Fig.1B).': [2422], 'When': [2423, 4683], 'coexpressed,': [2427], 'inhibited': [2429, 2436, 2500, 2548], 'AR-induced': [2430], 'TAT1-TATA.': [2439], 'series': [2442], 'titration': [2444], 'experiments,': [2445, 3811, 4020], 'found': [2447, 3817, 4023, 4188, 4270, 4309], 'inhibition': [2449, 2577, 3920, 4531, 4571], 'occurred': [2450], 'all': [2452, 2579], 'levels': [2453, 4612], 'suggesting': [2457, 4317], 'squelching': [2464], 'occlusion': [2466], 'heterodimer.': [2497, 3974], 'promoter.': [2515], '1C,': [2520], 'disparate': [2528], 'TAT3': [2530], 'TAT1': [2533, 2556], 'C′Δ9,': [2535], 'although,': [2536], 'like': [2537, 3830], 'TAT1,': [2538], 'considerably': [2541], 'more': [2542, 2552], 'AR.': [2545], 'Again,': [2546], 'activity,': [2550], 'albeit': [2551], 'modestly': [2553], '(Fig.': [2557, 3120, 3137, 3482, 4069], '1C,AR': [2558], '+': [2559, 3124, 3128, 3139, 3888, 4300, 4306], 'GR).': [2560], 'Thus,': [2561, 2868, 3003, 3581, 3827], 'variety': [2570, 4369], 'mutual': [2576, 2603, 3919, 4570], 'sites.': [2582], 'next': [2584], 'sought': [2585], 'determine': [2587], 'whether': [2588], 'physically': [2591], 'under': [2595], 'conditions': [2598], 'demonstrated': [2602, 2828, 2946, 3354, 3370, 3383, 3625, 4497], 'inhibition.': [2604], 'developed': [2609], 'salt': [2624, 2781, 2948, 3049, 3176, 3199, 3800], 'bridge': [2625, 2949, 3177, 3200, 3801], 'mutations': [2626, 2898, 2912, 2950, 3802, 4055], '(as': [2669, 2899], 'well': [2670, 3039], 'progesterone': [2672], 'receptor)': [2673, 4669], 'share': [2674], 'homology': [2680], 'regions': [2684, 3595], '(21Luisi': [2685, 2783], 'Xu': [2687, 2785], 'W.X.': [2688, 2786], 'Otwinowski': [2689, 2787], 'Z.': [2690, 2788], 'Freedman': [2691, 2736, 2789], '1991;': [2698, 2717, 2796, 2815, 5238], '352:': [2699, 2797], '497-505Crossref': [2700, 2798], '(1232)': [2703, 2801], '22Dahlman-Wright': [2706, 2804], 'Wright': [2708, 2806], 'J.-A.': [2711, 2809], 'Carlstedt-Duke': [2712, 2810], '266:': [2718, 2816], '3107-3112Abstract': [2719, 2817], '23Hard': [2726], 'Kellenbach': [2728], 'Boelens': [2730], 'Maler': [2732], 'B.A.': [2733], 'Dahlman': [2734], 'Carlstedt': [2738], 'D.J.': [2739, 4893], 'Kaptein': [2744], '1990;': [2747, 4159, 4755, 4800], '249:': [2748, 4160, 4756], '157-160Crossref': [2749], '(453)': [2752], 'Within': [2755], 'DBD,': [2757], 'conserved': [2759], 'Arg-Asn-Asp': [2760], 'motif': [2761], 'x-ray': [2765], 'crystallographic': [2766], 'analysis': [2767], 'participate': [2771], 'forming': [2776], 'reciprocal': [2778, 4691], 'pair': [2779, 2833], 'bridges': [2782], 'salt-bridge': [2832, 3858, 4276, 4527], 'contact': [2840, 3957, 5181], 'likely': [2871], 'would': [2876, 3082], 'AR-GR': [2878, 3471, 3529, 3569], 'well.': [2883], 'Initially': [2884], '2)': [2903], 'avoid': [2905], 'confounding': [2907], 'dimer': [2911, 3295, 3612, 3631, 3726, 3843, 3851, 3908, 3935, 3986, 4054, 4819, 4943, 5087, 5144, 5278, 5349], '(see': [2917, 3284], 'Scholar': [2941, 3697], 'below).': [2943], 'Previous': [2944], 'decrease': [2951], 'GRΔN': [2956, 3020, 3125, 3150], 'TAT1-': [2960], 'TAT3-containing': [2962], '3,': [3008, 3121], 'GRΔN/R479D': [3010], 'GRΔN/D481R': [3012], 'much': [3014], 'lower': [3015, 3034, 3820, 3891], 'when': [3021, 4337], 'cotransfected': [3022, 3193], 'Similarly,': [3025], 'homologous': [3027], 'Arg-Asp': [3028], 'ARΔN,': [3031], 'ARΔN/R581D,': [3032], 'ARΔN': [3037, 3123, 3148], '(Fig.3).': [3040], 'If': [3041], 'heterodimerized': [3045], 'bridge,': [3050], 'coexpression': [3052, 3131, 3706, 3872, 4524], 'should': [3056, 3094], 'reestablish': [3060, 3084], 'ionic': [3062, 3086], 'restore': [3065], 'consequently,': [3069], 'Coexpression': [3074, 3855], 'noncomplementary': [3076, 3874], 'mutants,': [3077, 3105], 'hand,': [3081], 'little': [3089, 5105], 'no': [3091, 5082], 'result.': [3095], 'keeping': [3097, 3417], 'prediction,': [3100], 'ARΔN/R581D': [3106, 3127], 'GRΔN/D481R,': [3108], 'fully': [3109], 'restored': [3110], 'compare': [3122, 3514], 'GRΔN/D481R)': [3129], 'non-complememtary': [3133], 'did': [3135, 3876], '3,ARΔN/R581D': [3138], 'GRΔN/R479D).': [3140], 'data': [3142, 4539, 5128, 5337], 'support': [3144, 3926, 4327, 5132], 'idea': [3146, 3848, 3928, 5031, 5136], 'TAT3-TATA': [3153, 3191, 4182], 'mediated': [3160, 4631, 4663], 'via': [3161, 3593], 'region.Figure': [3164], '3Genetic': [3165], 'interactionin': [3171], 'Complementary': [3173], 'non-complementary': [3175, 4303], 'cells.': [3190], 'shown.': [3203], 'nmcorticosterone': [3205], '1000': [3207], 'nm': [3208], 'represent': [3223], 'mean': [3225], '±': [3226], 'independent': [3230], 'experiments.View': [3231], 'Large': [3232], 'Image': [3233], 'Figure': [3234], 'ViewerDownload': [3235], 'Hi-res': [3236], 'image': [3237], 'Download': [3238], '(PPT)': [3239], 'look': [3241, 3399], 'assays': [3250], 'usingE.': [3251], 'coli-expressed': [3252], 'proteins': [3253, 3262], 'encompassing': [3254], 'DBDs.': [3257], 'truncated': [3261], 'differing': [3264], 'size': [3265, 3435], '(AR,': [3266], '11': [3267], 'kDa;': [3268], '19': [3270], 'partially': [3282], '"Experimental': [3285, 3460], 'Procedures").': [3286], 'unequivocally': [3288], 'identify': [3289], 'positions': [3291], 'monomer': [3293, 3359, 3388, 3477, 3492, 3541], 'bands': [3296, 3347, 3391, 3493], 'receptor,': [3299, 4867], 'analyzed': [3306], 'oligonucleotides': [3308, 3341, 3378], 'half': [3312], 'whole': [3317, 4373], '(two': [3320], 'separated': [3322], 'nucleotides).': [3325], 'Fig.4A,': [3329], 'highly': [3334, 3453, 5215], 'active': [3335], 'HRE-containing': [3340], 'relative': [3344], 'half-site': [3350, 5092, 5357], 'versus': [3351], 'locations': [3357], '(comparelanes': [3362], '3': [3363, 5282], '4).': [3365], 'Specificity': [3366], 'competition': [3372], 'cold': [3374], 'nonspecific': [3377], '(data': [3379, 3578, 3824, 4264], 'shown).': [3381, 3580, 3826, 4266], 'similar': [3385, 4288, 4655, 4727], 'result;': [3386], 'lanes': [3395, 3429, 3484, 3515], 'and6.': [3397], 'amounts': [3404], 'full-site': [3414], 'probe,': [3416], 'constant,': [3423], '4B,': [3428], '2–12.': [3430], 'band': [3432, 3473, 3478], 'intermediate': [3434, 3470], 'supporting': [3444, 3846], 'formation.': [3446, 4578], '(BuGR,': [3458], 'Procedures")': [3461], 'included,': [3463], 'upper': [3465], 'band,': [3468], 'complete': [3480], 'supershifted': [3481, 3496, 3573], '4C,': [3483], '5–7).': [3485], 'Although': [3486], 'absence': [3501], 'intensity': [3505], 'reduced': [3507], 'presence': [3510], '(Fig.4C,': [3513], '6).': [3518], 'This': [3519, 4579], 'stabilization': [3524], 'consequently': [3531], 'favoring': [3532], 'depleting': [3537], 'bands,': [3542], 'proteins.': [3550], 'Similar': [3551], 'supershift': [3552], 'results': [3553, 3911, 4180, 4326], 'HA/epitope-tagged': [3558], 'derivative': [3559], 'results,': [3584], 'conclude': [3586], 'vitro.': [3597], 'last': [3599], 'Recently,': [3606, 4974], 'role': [3608, 3931, 5140, 5368], 'interface': [3613, 3632, 3727, 3852, 3936, 3987, 4820, 4944, 5088, 5145, 5350], 'steroid': [3615, 5064, 5116], 'function': [3617], 'come': [3619], 'question.': [3621], 'Liu': [3622], 'disruption': [3627, 3839], 'context': [3635, 3971, 5075], 'increased': [3642, 3837, 4064], '(17Liu': [3648, 4093, 5161], 'striking': [3664], 'contrast': [3665], '(Ref.': [3674], '3).': [3700], 'Restoration': [3701], 'contacts': [3704], 'decreased': [3710, 4041, 4088], 'near': [3713], 'levels.': [3716], 'surprising': [3721], 'conclusion': [3722], 'restrains': [3728], 'interfering': [3732], 'capacity': [3735], 'synergy.': [3738], 'principle': [3744], '"constrained': [3745], 'self-synergy"': [3746], 'Arg-581': [3751], 'Asp': [3753], 'synergistic': [3762], '(AR/R581D)': [3768], 'examined.': [3770], '5,': [3775, 5284], '4-fold': [3781], 'greater': [3782], 'potentiated': [3797], 'parallel': [3808], 'set': [3809], 'self-synergy,': [3829, 3945], 'MR,': [3835], 'interfaces,': [3844], 'further': [3845, 3925, 5131], 'inhibitory.': [3854], 'returned': [3860], 'elevated': [3862], 'back': [3865], 'level,': [3870], 'not.': [3877], 'notable': [3880], 'elicited': [3885], 'GR/D481R': [3889], 'transmitted': [3904], 'interface.': [3909], 'strengthen': [3912], 'our': [3913, 5077], 'hypothesis': [3914, 4329], 'proceeds': [3921], 'heterodimerization': [3923, 5033], 'subfamily': [3940], 'limit': [3943], 'stabilize': [3948, 5149], 'occupancy': [3950, 5151, 5330], 'HRE,': [3953], 'i.e.': [3954], 'protein-protein': [3956], 'transmit': [3960], 'information': [3962, 5188], 'subunit': [3965], 'interesting': [3977, 5205], 'note': [3979, 4700, 5207], 'within': [3983], 'implicated': [3992], 'human': [3995], 'disease,': [3996], "Reifenstein's": [3997], 'syndrome': [3998], '(24Kaspar': [3999], 'Klocker': [4001], 'H.': [4002, 4227, 4351, 4796, 4824, 5255], 'Denninger': [4003], 'Cato': [4005, 4356, 4791], 'A.C.': [4006, 4357, 4792], '7850-7858Crossref': [4012], '(40)': [4015], 'transfection': [4019], 'Kasparet': [4021], 'surprisingly': [4029], 'unaffected': [4030, 4109], 'paired': [4035], 'simple': [4044, 4067, 4782], 'HRE.': [4045, 5334], 'find': [4048], 'context-dependent;': [4060], 'multiple': [4066, 5212], 'complex': [4112], 'interspersed': [4115], 'non-receptor': [4122], 'factors.': [4123], 'repress': [4139, 4279, 4738], 'AP-1': [4140, 4192, 4281, 4339, 4739, 4783], 'composite': [4144, 4744], 'GRE': [4145, 4745], 'reporter,': [4147], 'plfG': [4149], '(25Diamond': [4150, 4746], 'M.I.': [4151, 4747], 'Miner': [4152, 4748], 'J.N.': [4153, 4749], 'Yoshinaga': [4154, 4750], 'S.K.': [4155, 4751], '1266-1272Crossref': [4161, 4757], '(1068)': [4164, 4760], 'F9': [4171], 'showed': [4176], 'qualitatively': [4177], 'activation': [4190, 4282, 4340], 'repressed': [4194], '(26Bubulya': [4198], 'Wise': [4200], 'S.C.': [4201], 'Shen': [4202], 'X.Q.': [4203], 'Burmeister': [4204], 'L.A.': [4205], 'Shemshedini': [4206], 'L.': [4207], '271:': [4212], '24583-24589Abstract': [4213], '(96)': [4221], '27Kallio': [4224], 'P.J.': [4225, 4822], 'Poukka': [4226, 4823], 'Moilanen': [4228, 4825], 'Janne': [4230, 4827], 'O.A.': [4231, 4828], 'Palvimo': [4232, 4829], 'J.J.': [4233, 4830], '9:': [4237, 4834], '1017-1028Crossref': [4238, 4835], 'ligand-dependent': [4259], 'manner': [4260], 'reported': [4262], 'Interestingly,': [4267], 'transcription': [4284, 4647], 'type.': [4291], '(AR/R581D': [4299, 4305], 'GR/D481R)': [4301], 'GR/R479D),': [4307], 'repression': [4311, 4812], 'comparable': [4313], 'type,': [4316], 'heterodimerize.': [4324], 'monomers': [4336], 'repressing': [4338], '(28Heck': [4344], 'Kullmann': [4346], 'Gast': [4348], 'Ponta': [4350, 4795], 'Rahmsdorf': [4352, 4787], 'Herrlich': [4354, 4797], 'EMBO': [4358, 5256], '4087-4095Crossref': [4362], '(466)': [4365], 'studies': [4371], 'animals,': [4374], 'isolated': [4375], 'suggest': [4380, 4541, 5043, 5338], 'opposite': [4388], 'metabolism': [4392], 'mutually': [4401], 'vitro,': [4517], 're-establishing': [4520], 'restores': [4529], 'Taken': [4536], 'underlies': [4545], 'propose': [4554], 'due,': [4564], 'least': [4566], 'part,': [4568], 'important': [4582, 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