Advances and Challenges in Basic and Translational Research on Clusterin

Name: Work Video:
Duration: 3 min 30 s
Description: Clusterin (CLU), known by several other names, has recently drawn much attention because of its association with cancer promotion and metastasis ( [1][1]– [3][2]). First discovered as serum apolipoprotein J with chaperoning properties for protein stabilization, CLU also can exist within the cell
Ioannis P. Trougakos; Julie Y. Djeu; Efstathios S. Gonos; David A. Boothman
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Boothman', 'raw_affiliation_strings': ['4Departments of Oncology and Pharmacology, Program in Cell Stress and Cancer Nanomedicine, Laboratory of Molecular Stress Responses, University of Texas Southwestern Medical Center, Dallas, Texas'], 'affiliations': [{'raw_affiliation_string': '4Departments of Oncology and Pharmacology, Program in Cell Stress and Cancer Nanomedicine, Laboratory of Molecular Stress Responses, University of Texas Southwestern Medical Center, Dallas, Texas', 'institution_ids': ['https://openalex.org/I867280407']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.117, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 99, 'citation_normalized_percentile': {'value': 0.999943, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 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