Publication Information

{'id': 'https://openalex.org/W2057303408', 'doi': 'https://doi.org/10.1117/12.297790', 'title': '<title>Photodynamically induced cell cycle and gene expression changes: precursors of apoptosis introduction?</title>', 'display_name': '<title>Photodynamically induced cell cycle and gene expression changes: precursors of apoptosis introduction?</title>', 'publication_year': 1997, 'publication_date': '1997-12-29', 'ids': {'openalex': 'https://openalex.org/W2057303408', 'doi': 'https://doi.org/10.1117/12.297790', 'mag': '2057303408'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1117/12.297790', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S183492911', 'display_name': 'Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE', 'issn_l': '0277-786X', 'issn': ['0277-786X', '1996-756X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315543', 'host_organization_name': 'SPIE', 'host_organization_lineage': ['https://openalex.org/P4310315543'], 'host_organization_lineage_names': ['SPIE'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'proceedings-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5083958762', 'display_name': 'Barbara Krammer', 'orcid': 'https://orcid.org/0000-0001-5972-5258'}, 'institutions': [{'id': 'https://openalex.org/I182212641', 'display_name': 'University of Salzburg', 'ror': 'https://ror.org/05gs8cd61', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I182212641']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Barbara E. Krammer', 'raw_affiliation_strings': ['University of Salzburg Austria'], 'affiliations': [{'raw_affiliation_string': 'University of Salzburg Austria', 'institution_ids': ['https://openalex.org/I182212641']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018681266', 'display_name': 'Thomas Verwanger', 'orcid': 'https://orcid.org/0000-0003-2651-8898'}, 'institutions': [{'id': 'https://openalex.org/I182212641', 'display_name': 'University of Salzburg', 'ror': 'https://ror.org/05gs8cd61', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I182212641']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Thomas Verwanger', 'raw_affiliation_strings': ['University of Salzburg Austria'], 'affiliations': [{'raw_affiliation_string': 'University of Salzburg Austria', 'institution_ids': ['https://openalex.org/I182212641']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5005952534', 'display_name': 'Gerlinde Schnitzhofer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I182212641', 'display_name': 'University of Salzburg', 'ror': 'https://ror.org/05gs8cd61', 'country_code': 'AT', 'type': 'education', 'lineage': ['https://openalex.org/I182212641']}], 'countries': ['AT'], 'is_corresponding': False, 'raw_author_name': 'Gerlinde Schnitzhofer', 'raw_affiliation_strings': ['University of Salzburg Austria'], 'affiliations': [{'raw_affiliation_string': 'University of Salzburg Austria', 'institution_ids': ['https://openalex.org/I182212641']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.380749, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 55, 'max': 62}, 'biblio': {'volume': '3191', 'issue': None, 'first_page': '96', 'last_page': '106'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10957', 'display_name': 'Photodynamic Therapy Research Studies', 'score': 0.992, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10957', 'display_name': 'Photodynamic Therapy Research Studies', 'score': 0.992, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.963, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11440', 'display_name': 'Click Chemistry and Applications', 'score': 0.9561, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.8169546}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.7990397}, {'id': 'https://openalex.org/C2781018059', 'wikidata': 'https://www.wikidata.org/wiki/Q207609', 'display_name': 'Oncogene', 'level': 4, 'score': 0.67316353}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.5812439}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.5793788}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.5289697}, {'id': 'https://openalex.org/C105696609', 'wikidata': 'https://www.wikidata.org/wiki/Q1068809', 'display_name': 'Cell cycle checkpoint', 'level': 4, 'score': 0.47557202}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.47190958}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.45995274}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.44886577}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.41437572}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.40505776}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.40404627}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3479386}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.15463144}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1117/12.297790', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S183492911', 'display_name': 'Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE', 'issn_l': '0277-786X', 'issn': ['0277-786X', '1996-756X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315543', 'host_organization_name': 'SPIE', 'host_organization_lineage': ['https://openalex.org/P4310315543'], 'host_organization_lineage_names': ['SPIE'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.65, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3161809393', 'https://openalex.org/W3107603624', 'https://openalex.org/W3032526538', 'https://openalex.org/W3022642502', 'https://openalex.org/W2561416304', 'https://openalex.org/W2387704253', 'https://openalex.org/W2193001123', 'https://openalex.org/W2120086268', 'https://openalex.org/W1995228374', 'https://openalex.org/W1972085353'], 'abstract_inverted_index': {'Photodynamic': [0], 'tumor': [1, 161], 'therapy': [2], 'is': [3, 12], 'able': [4], 'to': [5, 21, 61, 88, 132], 'induce': [6], 'apoptosis': [7], 'with': [8, 47, 55], 'many': [9], 'photosensitizers.': [10], 'Apoptosis': [11], 'based': [13], 'on': [14], 'changes': [15, 93], 'in': [16, 40, 59, 94, 136, 163, 177, 182], 'gene': [17, 190], 'expression': [18, 33, 75, 191], 'and': [19, 38, 42, 49, 91, 124, 153, 180, 192], 'correlated': [20], 'cell': [22, 56, 83, 129], 'cycle': [23, 57, 84, 130], 'activities.': [24], 'In': [25], 'this': [26], 'study,': [27], 'therefore,': [28], 'quantitative': [29], 'determination': [30], 'of': [31, 34, 68, 81, 96, 109, 122, 140, 144, 151, 158, 160, 170], 'the': [32, 35, 82, 89, 97, 133, 141, 145, 149, 168, 178, 183], '(proto)oncoges': [36], 'c-myc': [37, 123], 'bcl-2': [39, 152], 'normal': [41, 196], 'transformed': [43, 146], 'fibroblasts': [44], 'following': [45], 'PDT': [46, 176], 'ALA': [48], 'low': [50, 174], 'dose': [51, 175], 'irradiation': [52], 'was': [53], 'connected': [54], 'analysis': [58], 'order': [60], 'investigate,': [62], 'if': [63, 79, 92], 'a': [64, 156], 'risk': [65, 117, 157], 'for': [66], 'occurrence': [67], 'secondary': [69], 'tumors': [70], 'by': [71, 118, 148, 173], 'irreversibly': [72], 'increased': [73], 'oncogene': [74], 'can': [76], 'be': [77], 'found,': [78], 'phases': [80], 'show': [85, 113, 187], 'selective': [86, 128], 'sensitivity': [87, 131], 'therapy,': [90], 'one': [95], 'two': [98], 'or': [99, 105], 'both': [100], 'parameters': [101], 'may': [102], 'either': [103], 'precede': [104], 'prepare': [106], 'an': [107], 'introduction': [108, 169], 'apoptosis.': [110], 'The': [111], 'results': [112], '(1)': [114], 'no': [115, 127], 'mutagenic': [116], 'timely': [119], 'limited': [120], 'overexpression': [121], 'bcl-2,': [125], '(2)': [126], 'therapy;': [134], 'but,': [135], 'contrary,': [137], 'sustained': [138], 'increase': [139], 'proliferative': [142, 193], 'activity': [143], 'cells': [147, 186], 'interaction': [150], 'c-myc,': [154], 'indicating': [155], 'promotion': [159], 'regrowth': [162], 'sublethally': [164], 'damaged': [165], 'areas,': [166], '(3)': [167], 'apoptotic': [171], 'processes': [172], 'cytoplasm/mitochondria': [179], 'less': [181], 'nucleus.': [184], 'Transformed': [185], 'higher': [188], 'constitutive': [189], 'activities': [194], 'than': [195], 'cells.': [197]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2057303408', 'counts_by_year': [], 'updated_date': '2024-12-08T11:04:16.043919', 'created_date': '2016-06-24'}