Title: The pathogenesis of chronic idiopathic urticaria: new evidence suggests an auto–immune basis and implications for treatment
Abstract: Clinical & Experimental AllergyVolume 24, Issue 7 p. 624-627 The pathogenesis of chronic idiopathic urticaria: new evidence suggests an auto–immune basis and implications for treatment M. HIDE, M. HIDE Onomichi General Hospital, Hiroshima, Japan.Search for more papers by this authorD. M. FRANCIS, D. M. FRANCIS St John's Institute of Dermatology, United Medical and Dental Schools, St Thomas’ Hospital, London. UKSearch for more papers by this authorC. E. H. GRATTAN, C. E. H. GRATTAN †Norfolk and Norwich Hospital. Norwich. UK.Search for more papers by this authorR. M. BARR, R. M. BARR St John's Institute of Dermatology, United Medical and Dental Schools, St Thomas’ Hospital, London. UKSearch for more papers by this authorR. K. WINKELMANN, R. K. WINKELMANN ‡Mayo Clinic Scottsdale, Arizona, USA.Search for more papers by this authorM. W. GREAVES, Corresponding Author M. W. GREAVES St John's Institute of Dermatology, United Medical and Dental Schools, St Thomas’ Hospital, London. UKProfessor M. W. Greaves, St John's Institute of Dermatology, St Thomas' Hospital, Lambeth Palace Road. London SE1 7EH, UK.Search for more papers by this author M. HIDE, M. HIDE Onomichi General Hospital, Hiroshima, Japan.Search for more papers by this authorD. M. FRANCIS, D. M. FRANCIS St John's Institute of Dermatology, United Medical and Dental Schools, St Thomas’ Hospital, London. UKSearch for more papers by this authorC. E. H. GRATTAN, C. E. H. GRATTAN †Norfolk and Norwich Hospital. Norwich. UK.Search for more papers by this authorR. M. BARR, R. M. BARR St John's Institute of Dermatology, United Medical and Dental Schools, St Thomas’ Hospital, London. UKSearch for more papers by this authorR. K. WINKELMANN, R. K. WINKELMANN ‡Mayo Clinic Scottsdale, Arizona, USA.Search for more papers by this authorM. W. GREAVES, Corresponding Author M. W. GREAVES St John's Institute of Dermatology, United Medical and Dental Schools, St Thomas’ Hospital, London. UKProfessor M. W. Greaves, St John's Institute of Dermatology, St Thomas' Hospital, Lambeth Palace Road. London SE1 7EH, UK.Search for more papers by this author First published: July 1994 https://doi.org/10.1111/j.1365-2222.1994.tb00965.xCitations: 61 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Champion RH, Roberts SOB, Carpenter RG. Roger JH. Urticaria and angio–oedema. A review of 554 patients. Br J Dermatol 1969: 81: 588– 97. 2 Juhlin L. Recurrent urticaria: a clinical investigation of 330 patients. Br J Dermatol 1981: 104: 369– 81. 3 Sibbald RG. Cheema AS, Lozinski A, Tarle S. Chronic urticaria: evaluation of the role of physical immunologic or other contributory factors. Int J Dermatol 1991; 30: 381– 6. 4 Leznoff A. Sussman GL. Syndrome of idiopathic chronic urticaria and angioedema with thyroid autoimmunity: A study of 90 patients. J Allergy Clin Immunol 1989; 84: 66– 71. 5 Natbony SF, Phillips ME, Elias JM, Godfrey HP, Kaplan AP. Histological studies of chronic idiopathic urticaria. J Allergy Clin Immunol 1983; 71: 177– 83. 6 Winkelmann RK. Reizner GT. Diffuse dermal neutrophils in urticaria. Human Pathol 1988; 19: 389– 93. 7 Elias J, Boss E, Kaplan AP. Studies of the cellular infiltrate of chronic urticaria: prominence of T–lymphocytes, monocytes and mast cells. J Allergy Clin Immunol 1986; 78: 914– 8. 8 Kaplan AP, Horokova Z. Katz SI. Assessment of tissue fluid histamine levels in patients with urticaria. J Allergy Clin Immunol 1978; 61: 350– 4. 9 Greaves M, Shuster S. Responses of the skin blood vessels to bradykinin histamine and 5–hydroxy–tryptamine. J Physiol 1967; 193: 255– 67. 10 Krause LB, Shuster S. Enhanced weal and flare response to histamine in chronic idiopathic urticaria. Br J Clin Pharimicol 1985; 20: 486– 8. 11 Juhlin L. Late phase cutaneous reaction to platelet activating factor and kallikrein in urticaria. Clin Exp Allergy 1990; 20:suppl 4: 9– 10. 12 Smith CH, Atkinson B, Morris RW et al. Cutaneous responses to vasoactive intestinal polypeptide in chronic idiopathic urticaria. Lancet 1992; 339: 91– 3. 13 Rorsman H. Basophilic leucopenia in different forms of urticaria. Acta Allergologica 1962; 17: 168– 84. 14 Greaves MW, Plummer VM, McLaughlan P, Stanworth DR. Serum and cell bound IgE in chronic urticaria. Clin Allergy 1974; 4: 265– 71. 15 Kern F, Lichtenstein LM. Defective histamine release in chronic urticaria. J Clin Invest 1976; 57: 1369– 77. 16 Grattan CEH. Wallington TB, Warin RP. Kennedy CTC, Uradfield JW. A serological mediator in chronic idiopathic urticaria–a clinical, immunological and histological evaluation. Br J Dermatol 1986; 114: 583– 90. 17 Grattan CEH, Boon AP, Eady RAJ, Winklemann RK. The pathology of the autologous serum skin test response in chronic urticaria resembles IgE–mediated late phase reaction. Int Arch Allergy Appl Immunol 1990; 93: 198– 204. 18 Grattan CEH, Francis DM, Hide M, Greaves MW. Detection of circulating histamine–releasing autoantibodies with functional properties of anti–lgE in chronic urticaria. Clin Exp Allergy 1992; 21: 695– 704. 19 Gruber BL, Baeza ML. Marchese MJ, Agnello V, Kaplan AP. Prevalence and functional role of anti–IgE auto–antibodies in urticarial syndromes. J Invest Dermatol 1988; 90: 213– 7. 20 Marone G. Casolaro V, Paganelli R, Quinti I. IgG anti–IgE from atopic dermatitis induces mediator release from basophils and mast cells. J Invest Dermatol 1989; 93: 246– 52. 21 Twena DM. Marshall JS, Haeney MR. Bell EB. A survey of non–atopic and atopic children and adults for the presence of anti–IgE autoantibodies. Clin Immunol Immumipathol 1989; 53: 40– 51. 22 Hide M, Francis DM, Grattan CEH et al. Auto–antibodies against the high affinity IgE receptors as a cause of histamine release in chronic urticaria. New Engl J Med 1993; 328: 1599– 604. 23 Grattan CEH, Francis DM, Slater NGP, Barlow RJ, Greaves MW. Plasmapheresis for severe unremitting chronic urticaria. Lancet 1992; 339: 1078– 80. 24 Zhang B, Roth RA. A region of the insulin receptor important for ligand binding (residues 450–601) is recognized by patients' autoimmune antibodies and inhibitory monoclonal antibodies. Proc Natl Acad Sci USA 1991; 88: 9858– 62. 25 Heinemann S, Bevan S, Kullberg R, Lindstrom J, Rice J. Modulation of the acetylcholine receptor by antibody against the receptor, Proc Natl Acad Sci USA 1977; 74: 3090– 9. 26 Smith BR, Hall R. Thyroid–stimulating immunoglobulins in Graves' disease. Lancet 1974; 2: 427– 31. 27 Witebsky E, Rose NR, Terplan K, Paine JR, Egan RW. Chronic thyroiditis and autoimmunization. J Am Med Assoc 1957; 164. 1439– 47. 28 Barlow RJ, Black AK, Greaves MW. Treatment of severe chronic urticaria with cyclosporin A. Eur J Dermatol 1993; 3: 273– 5. 29 Gelfand EW. Intervention in autoimmune disorders: creation of a niche for intravenous gamma globulin therapy. Clin Immunol Immunopathol 1989; 53: S1– 6. Citing Literature Volume24, Issue7July 1994Pages 624-627 ReferencesRelatedInformation
Publication Year: 1994
Publication Date: 1994-07-01
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 72
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