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684, 715], 'R.': [223, 242, 1129], 'VON': [225], 'ALBERT,': [226], 'H.-H.': [227], '(1980)': [228], 'Pharmacokinetics': [229, 244, 698, 774, 1110], 'benzodiazepines—Short-acting': [231], 'versus': [232], 'long-acting.': [233], 'Arzneim.-Forsch.,': [234], '30,': [235, 573, 922], '875–': [236], '881.': [237], 'D.D.': [239, 324, 696, 725, 751], '(1981).': [243, 410, 558, 752, 911, 1164], 'hypnotic': [246], 'drugs.': [247, 677], 'In': [248, 275], 'Psychopharmacology': [249], 'Sleep,': [251], 'ed.': [252], 'D.W.': [253], 'Wheatley,': [254], 'pp.': [255, 286], '135–': [256], '153.': [257], 'New': [258, 1004], 'York:': [259, 1005], 'Raven': [260], 'Press.': [261, 291], 'CASTLEDEN,': [262, 292], 'C.M.': [263], 'GEORGE,': [265, 294], 'C.F.': [266], '(1979).': [267, 491, 868, 1091, 1109], 'Increased': [268, 302], 'sensitivity': [269, 303], 'benzodiazepines': [271], 'in': [272, 306, 332, 344, 368, 389, 460, 494, 565, 590, 596, 621, 629, 662, 673, 707, 777, 854, 873, 950, 974, 992, 1019, 1096, 1115, 1138, 1172, 1204], 'elderly.': [274, 431, 445, 496, 875, 1020, 1117], 'Drugs': [276, 428], 'Elderly,': [279], 'eds.': [280], 'J.': [281, 346, 420, 473, 540, 600, 639, 709, 741, 822, 857, 877, 900, 1160, 1182, 1206], 'Crooks': [282], 'I.H.': [284], 'Stevenson,': [285], '169–': [287], '178.': [288], 'London:': [289], 'Macmillan': [290], 'C.M.,': [293], 'C.F.,': [295], 'MARCER,': [296], 'D.': [297, 968], 'HALLETT,': [299], 'C.': [300, 965], '(1977).': [301, 427], 'nitrazepam': [305, 329, 459, 706, 776, 1016], 'old': [307], 'Br.': [309, 446, 472, 678, 740, 876], 'med.': [310, 447, 679], 'J.,': [311, 319, 448, 680, 689, 691, 797, 805], '1,': [312, 681], '10–': [313], '12.': [314], 'DE': [315, 1158], 'BOER,': [316], 'A.G.,': [317, 608], 'RÖST-KAISER,': [318], 'BRACHT,': [320], 'H.': [321, 617, 1087], 'Assay': [326], 'underivatized': [328], 'clonazepam': [331], 'plasma': [333], 'capillary': [335], 'gas': [336], 'chromatography': [337], 'applied': [338], 'pharmacokinetic': [340], 'bioavailability': [342, 700], 'studies': [343], 'humans.': [345, 708], 'Chromatogr.,': [347], '145,': [348], '105–': [349], '114.': [350], 'DESMOND,': [351, 927, 1028], 'P.V.,': [352, 928, 1029], 'PATWARDHAN,': [353, 1024], 'R.V.,': [354, 1025], 'SCHENKER,': [355, 834, 936, 1032, 1058, 1131], 'S.': [356, 835, 937, 1033, 1059, 1132], 'SPEEG,': [358, 1035], 'K.V.': [359], 'Jr.': [360], '(1980).': [361, 386, 888, 969, 1038], 'Cimetidine': [362, 1039], 'impairs': [363], 'elimination': [365, 851, 870], 'chlordiazepoxide': [367, 1072], 'man.': [369, 663, 856, 951, 1205], 'Ann.': [370, 1144], 'Intern.': [371, 1145], 'Med.,': [372, 1146], '93,': [373], '266–': [374], '268.': [375], 'ALLEN,': [376, 454, 481, 505], 'DIVOLL': [377, 482, 506], 'M.,': [378, 402, 483, 507, 526, 550, 579, 612, 720], 'GREENBLATT,': [379, 403, 451, 479, 503, 523, 547, 576, 987, 1080, 1107], 'D.J.,': [380, 404, 480, 504, 524, 548, 577, 1081], 'HARMATZ,': [381, 405, 486, 508, 527, 551, 582], 'J.S.': [382, 406, 487, 509, 528, 583], 'SHADER,': [384, 408, 489, 511, 530, 556, 585, 1104], 'R.I.': [385, 409, 490, 512, 531, 557, 586, 1105], 'Desmethyldiazepam': [387], 'kinetics': [388, 493, 589], 'elderly': [391, 568], 'after': [392, 631, 781], 'oral': [393, 703, 733, 784], 'prazepam.': [394], '28,': [398], '196–': [399], '202.': [400], 'DIVOLL,': [401, 525, 549, 578], 'gender': [415], 'temazepam.': [419], 'pharm.': [421], 'Sci.,': [422], '70,': [423], '1104–': [424], '1108.': [425], 'EDITORIAL.': [426], 'Lancet,': [432, 1021], 'ii,': [433], '693–': [434], '694.': [435], 'EVANS,': [436], 'J.G.': [437], 'JARVIS,': [439], 'E.H.': [440], '(1972).': [441, 1197], 'Nitrazepam': [442], '4,': [449], '487.': [450], 'D.J.': [452, 988, 1108], 'M.D.': [455, 1193], 'Toxicity': [457], 'elderly:': [462], 'report': [464], 'from': [465], 'Boston': [467, 998], 'collaborative': [468, 999], 'drug': [469, 625, 1000, 1113], 'surveillance': [470, 1001], 'program.': [471], 'clin.': [474, 640, 742, 823, 858, 878, 901, 1183], 'Pharmac.,': [475, 641, 743, 824, 879, 902, 1208], '5,': [476], '407–': [477], '413.': [478], 'LOCKNISAR,': [484], 'A.,': [485, 833, 963], 'Lorazepam': [492], '103–': [501], '113.': [502], '(1980a).': [513], 'Diazepam': [514], 'determinants.': [516], '27,': [520], '301–': [521], '312.': [522], '(1980b).': [532], 'Oxazepam': [533], 'kinetics:': [534], 'effects': [535, 562, 940, 991, 1114], 'sex.': [539], 'exp.': [542, 602], '215,': [544], '86–': [545], '91.': [546], 'J.S.,': [552], 'MACLAUGHLIN,': [553], 'D.S.': [554], 'Kinetics': [559], 'clinical': [561, 1112], 'flurazepam': [564], 'young': [566], 'noninsomniacs.': [569], '475–': [574], '486.': [575], 'ABERNETHY,': [580], 'D.R.,': [581], '(1982).': [587, 1012], 'Antipyrine': [588], 'elderly-prediction': [592], 'age-related': [594], 'changes': [595], 'benzodiazepine': [597], 'oxidizing': [598], 'capactiy.': [599], '220,': [604], '120–': [605], '126.': [606], 'HILDEBRANDT,': [607], 'ROOTS,': [609], 'I.,': [610, 803], 'SPECK,': [611], 'SAALFRANK,': [613], 'K.': [614, 1011], 'KEWITZ,': [616], '(1975).': [618, 839], 'Evaluation': [619], 'vivo': [622], 'parameters': [623], 'metabolizing': [626], 'enzyme': [627, 972, 1202], 'activity': [628], 'man': [630], 'administration': [632], 'clemastine,': [634], 'phenobarbital': [635], 'or': [636], 'placebo.': [637], 'Eur.': [638, 821, 899], '8,': [642], '327–': [643], '336.': [644], 'HUFFMAN,': [645], 'D.H.,': [646], 'SHOEMAN,': [647], 'D.W.,': [648], 'PENTIKÁINEN,': [649], 'P.': [650, 867], 'AZARNOFF,': [652], 'D.L.': [653], '(1973).': [654], 'effect': [656, 816, 841], 'spironolactone': [658], 'antipyrine': [660, 1170], 'metabolism': [661], 'Pharmacology,': [664], '10,': [665, 712], '338–': [666], '344.': [667], 'HURWITZ,': [668], 'N.': [669], '(1969).': [670], 'Predisposing': [671], 'factors': [672], 'adverse': [674], 'reactions': [675], '536–': [682], '539.': [683], 'R.,': [685, 716, 767], 'HOGENDOORN,': [686], 'J.J.H.,': [687], 'DINGEMANSE,': [688], 'HERMANS,': [690], 'BOEIJINGA,': [692, 721], 'J.K.': [693, 722], '(1982a).': [697], 'intravenous,': [702], 'rectal': [705], 'Pharmacokin.': [710], 'Biopharm.,': [711], '231–': [713], '245.': [714], 'VAN': [717], 'DER': [718], 'GRAAFF,': [719], '(1982b).': [726], 'Influence': [727, 889], 'sex,': [729], 'menstrual': [730], 'cycle': [731], 'contraception': [734], '13,': [744], '319–': [745], '324.': [746], 'KANGAS,': [747, 762, 792], 'L.': [748], 'Pharmacokin.,': [758], '6,': [759], '346–': [760], '366.': [761], 'L.,': [763, 793], 'ALLONEN,': [764], 'H.,': [765], 'LAMMINTAUSTA,': [766], 'SALONEN,': [768], 'M.': [769, 807], 'PEKKARINEN,': [771], 'A.': [772], '(1979a).': [773], 'saliva': [778], 'serum': [780], 'single': [783], 'dose.': [785], 'Acta': [786], 'Tox.,': [788, 1186], '45,': [789], '20–': [790], '24.': [791], 'IISALO,': [794], 'E.,': [795, 1157], 'KANTO,': [796], 'LEHTINEN,': [798], 'V.,': [799], 'PYNNÖNEN,': [800], 'S.,': [801], 'RUIKKA,': [802], 'SALMINEN,': [804], 'SILLANPÄÄ,': [806], 'SYVÄLAHTI,': [809], '(1979b).': [811], 'Human': [812], 'nitrazepam:': [815], 'disease.': [820], '163–': [826], '170.': [827], 'KLOTZ,': [828, 863, 883, 906], 'U.,': [829], 'AVANT,': [830], 'G.R.,': [831, 1054, 1127], 'HOYUMPA,': [832], 'WILKINSON,': [837, 933, 1053, 1126], 'G.R.': [838, 934], 'disease': [846, 945, 1067], 'diazepam': [853, 915], 'adult': [855], 'Invest.,': [859], '55,': [860], '347–': [861], '359.': [862], 'U.': [864, 884, 907], 'MÜJLLER-SEYDLITZ,': [866], 'Altered': [869], 'desmethyldiazepam': [872, 896], '7,': [880], '119–': [881], '120.': [882], 'REIMANN,': [886, 909], 'I.': [887, 910], 'cimetidine': [891, 1168], 'oxazepam.': [898, 1046], '18,': [903], '517–': [904], '520.': [905], 'Elevation': [912], 'steady-state': [914], 'levels': [916], 'cimetidine.': [918], '513–': [923], '517.': [924], 'KRAUSS,': [925], 'J.W.,': [926], 'MARSHALL,': [929], 'J.P.,': [930, 959], 'JOHNSON,': [931, 1030, 1128], 'R.F.,': [932, 1031], 'ageing': [942], 'oflorazepam': [949], '24,': [955, 1209], '411–': [956], '419.': [957], 'MIGUET,': [958], 'VUITTON,': [960], 'D.,': [961], 'THEBAULT-LUCAS,': [962], 'JOANNE,': [964], 'DHUMEAUX,': [967], 'Spironolactone': [970, 1198], 'induction': [973], 'patients': [975, 1173], 'alcoholic': [977], 'cirrhosis.': [979, 1097, 1143], 'Gasteroenterlogy,': [980], '78,': [981], '996–': [982], '1000.': [983], 'MILLER,': [984], 'R.R.': [985], '(1976).': [989, 1133], 'Drug': [990], 'hospitalized': [993], 'patients:': [994], 'experiences': [995], 'program,': [1002], '1966–1975.': [1003], 'John': [1006], 'Sons.': [1009], 'MORGAN,': [1010], 'low-dose': [1015], 'performance': [1018], 'i,': [1022], '516.': [1023], 'YARBOROUGH,': [1026], 'G.W.,': [1027], 'K.V.,': [1036], 'jr': [1037], 'spares': [1040], 'glucuronidation': [1042], 'lorazepam': [1044], 'Gastroenterology,': [1047, 1074], '79,': [1048], '912–': [1049], '916.': [1050], 'ROBERTS,': [1051], 'R.K.,': [1052], 'BRANCH,': [1055], 'R.A.': [1056], 'parenchymal': [1065], '(Librium).': [1073], '75,': [1075], '479–': [1076], '485.': [1077], 'SELLERS,': [1078], 'E.M.,': [1079], 'GILES,': [1082], 'H.G.,': [1083], 'NARANJO,': [1084], 'C.A.,': [1085], 'KAPLAN,': [1086], 'MACLEOD,': [1089], 'S.M.': [1090], 'Chlordiazepoxide': [1092], 'oxazepam': [1094, 1137], '240–': [1102], '246.': [1103], 'Psychopharmac.': [1118], 'Bull.,': [1119], '8–': [1121], '14.': [1122], 'SHULL,': [1123], 'H.J.': [1124], 'Jr.,': [1125], 'Normal': [1134], 'acute': [1139], 'viral': [1140], 'hepatitis': [1141], '84,': [1147], '420–': [1148], '425.': [1149], 'STAIGER,': [1150], 'C.H.,': [1151, 1153], 'MANNER,': [1152], 'CZYGAN,': [1154], 'P.,': [1155], 'WALTER,': [1156], 'VRIES,': [1159], 'WEBER,': [1162], 'without': [1176], 'liver.': [1180], 'Int.': [1181], 'Ther.': [1185], '19,': [1187], '561–': [1188], '564.': [1189], 'TAYLOR,': [1190], 'S.A.,': [1191], 'RAWLINS,': [1192], 'SMITH,': [1195], 'S.E.': [1196], '—': [1199], 'weak': [1201], 'inducer': [1203], 'Pharm.': [1207], '578–': [1210], '579.': [1211], 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