Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2056340939', 'doi': 'https://doi.org/10.1016/j.mce.2011.08.035', 'title': 'Nuclear hormone receptors: Allosteric switches', 'display_name': 'Nuclear hormone receptors: Allosteric switches', 'publication_year': 2012, 'publication_date': '2012-01-01', 'ids': {'openalex': 'https://openalex.org/W2056340939', 'doi': 'https://doi.org/10.1016/j.mce.2011.08.035', 'mag': '2056340939', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21906655'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.mce.2011.08.035', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191044671', 'display_name': 'Molecular and Cellular Endocrinology', 'issn_l': '0303-7207', 'issn': ['0303-7207', '1872-8057'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'editorial', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056247791', 'display_name': 'Iain J. McEwan', 'orcid': 'https://orcid.org/0000-0003-2087-0663'}, 'institutions': [{'id': 'https://openalex.org/I195460627', 'display_name': 'University of Aberdeen', 'ror': 'https://ror.org/016476m91', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I195460627']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'Iain J. McEwan', 'raw_affiliation_strings': ['School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2RS, Scotland, UK'], 'affiliations': [{'raw_affiliation_string': 'School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2RS, Scotland, UK', 'institution_ids': ['https://openalex.org/I195460627']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5056247791'], 'corresponding_institution_ids': ['https://openalex.org/I195460627'], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.815385, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '348', 'issue': '2', 'first_page': '345', 'last_page': '347'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10756', 'display_name': 'Mechanisms of Estrogen Receptor Signaling', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10756', 'display_name': 'Mechanisms of Estrogen Receptor Signaling', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11839', 'display_name': 'Management of Primary Aldosteronism', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11559', 'display_name': 'Role of Retinoic Acid in Biological Processes', 'score': 0.9849, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nuclear-receptors', 'display_name': 'Nuclear Receptors', 'score': 0.603203}, {'id': 'https://openalex.org/keywords/primary-aldosteronism', 'display_name': 'Primary Aldosteronism', 'score': 0.574867}, {'id': 'https://openalex.org/keywords/aldosterone', 'display_name': 'Aldosterone', 'score': 0.543514}, {'id': 'https://openalex.org/keywords/pml-nuclear-bodies', 'display_name': 'PML Nuclear Bodies', 'score': 0.535517}, {'id': 'https://openalex.org/keywords/differentiation-therapy', 'display_name': 'Differentiation Therapy', 'score': 0.506583}], 'concepts': [{'id': 'https://openalex.org/C166342909', 'wikidata': 'https://www.wikidata.org/wiki/Q845326', 'display_name': 'Allosteric regulation', 'level': 3, 'score': 0.850474}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.68312764}, {'id': 'https://openalex.org/C63932345', 'wikidata': 'https://www.wikidata.org/wiki/Q422500', 'display_name': 'Nuclear receptor', 'level': 4, 'score': 0.58805305}, {'id': 'https://openalex.org/C23589133', 'wikidata': 'https://www.wikidata.org/wiki/Q412005', 'display_name': 'Hormone receptor', 'level': 4, 'score': 0.50693876}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.46018228}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.44843006}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.41866928}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3335668}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.323802}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.28217304}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.23746124}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.13144484}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.100476325}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.093502164}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000494', 'descriptor_name': 'Allosteric Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006728', 'descriptor_name': 'Hormones', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006728', 'descriptor_name': 'Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046912', 'descriptor_name': 'Multiprotein Complexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046912', 'descriptor_name': 'Multiprotein Complexes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018160', 'descriptor_name': 'Receptors, Cytoplasmic and Nuclear', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D020218', 'descriptor_name': 'Response Elements', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.mce.2011.08.035', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191044671', 'display_name': 'Molecular and Cellular Endocrinology', 'issn_l': '0303-7207', 'issn': ['0303-7207', '1872-8057'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21906655', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger', 'score': 0.43}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1501286679', 'https://openalex.org/W1989444478', 'https://openalex.org/W1996127793', 'https://openalex.org/W2012324003', 'https://openalex.org/W2025919590', 'https://openalex.org/W2028605407', 'https://openalex.org/W2037505500', 'https://openalex.org/W2038208040', 'https://openalex.org/W2061357909', 'https://openalex.org/W2074522426', 'https://openalex.org/W2083054591', 'https://openalex.org/W2089409283', 'https://openalex.org/W2096594220', 'https://openalex.org/W2105259330', 'https://openalex.org/W2149044745'], 'related_works': ['https://openalex.org/W747883771', 'https://openalex.org/W4388227751', 'https://openalex.org/W4240468112', 'https://openalex.org/W3143659456', 'https://openalex.org/W2409183130', 'https://openalex.org/W2035029381', 'https://openalex.org/W1973309749', 'https://openalex.org/W167346798', 'https://openalex.org/W141312638', 'https://openalex.org/W121435057'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2056340939', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-08-13T23:43:34.562011', 'created_date': '2016-06-24'}