Publication Information

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'https://openalex.org/W2038445236', 'https://openalex.org/W2016442940', 'https://openalex.org/W2002812554', 'https://openalex.org/W1995532774', 'https://openalex.org/W1990149642'], 'abstract_inverted_index': {'C-reactive': [0, 199, 486, 520, 528, 652, 660, 750, 793, 843, 1178, 1330, 1408, 1625, 1633, 1675, 1712, 2047, 4326, 4334], 'protein': [1, 148, 200, 347, 458, 521, 529, 653, 661, 751, 794, 844, 1179, 1219, 1271, 1331, 1409, 1626, 1634, 1676, 1713, 1913, 2048, 2415, 2652, 3780, 4207, 4240, 4327, 4335], '(CRP)': [2, 201], 'is': [3, 202, 539, 548, 1091, 1249, 1572, 1647, 2990, 3009, 3029, 4139, 4256], 'present': [4, 203, 543, 806, 856, 1861, 3631], 'in': [5, 25, 35, 45, 53, 67, 69, 77, 135, 189, 197, 204, 224, 234, 244, 252, 266, 268, 276, 334, 388, 396, 405, 424, 440, 444, 465, 478, 492, 544, 551, 561, 589, 595, 625, 807, 826, 857, 885, 928, 988, 1011, 1047, 1131, 1155, 1157, 1305, 1340, 1383, 1413, 1428, 1466, 1504, 1548, 1566, 1576, 1602, 1610, 1645, 1657, 1685, 1723, 1816, 1835, 1856, 1877, 2077, 2167, 2243, 2313, 2385, 2409, 2472, 2556, 2592, 2657, 2665, 2680, 2687, 2705, 2710, 2773, 2802, 2981, 3037, 3168, 3209, 3252, 3293, 3324, 3337, 3381, 3420, 3455, 3486, 3591, 3606, 3632, 3657, 3699, 3721, 3728, 3778, 3812, 3869, 3898, 3912, 3922, 4054, 4058, 4081, 4136, 4292, 4314], 'the': [6, 57, 78, 193, 205, 256, 277, 392, 401, 406, 450, 460, 552, 629, 827, 954, 959, 1102, 1108, 1128, 1172, 1182, 1243, 1269, 1293, 1302, 1306, 1346, 1540, 1565, 1581, 1592, 1603, 1768, 1782, 1790, 1812, 1831, 1839, 1860, 1867, 2009, 2017, 2220, 2333, 2469, 2495, 2525, 2633, 2637, 2711, 2715, 2734, 2744, 2803, 2816, 2842, 2977, 3022, 3033, 3049, 3069, 3073, 3091, 3115, 3140, 3150, 3156, 3169, 3178, 3188, 3194, 3210, 3225, 3231, 3257, 3267, 3275, 3294, 3304, 3338, 3342, 3366, 3369, 3371, 3382, 3392, 3461, 3464, 3466, 3477, 3487, 3560, 3588, 3601, 3613, 3633, 3638, 3668, 3722, 3729, 3759, 3773, 3875, 3890, 4034, 4038, 4047, 4055, 4167, 4193, 4228, 4274, 4293], 'atherosclerotic': [7, 27, 206, 226, 545, 887, 1349, 1836, 2315], 'plaques': [8, 207], 'and': [9, 23, 42, 64, 80, 118, 126, 154, 178, 208, 222, 241, 263, 279, 317, 325, 353, 377, 410, 422, 442, 547, 592, 634, 641, 709, 711, 757, 795, 822, 845, 883, 926, 930, 933, 948, 963, 986, 1016, 1076, 1110, 1202, 1336, 1418, 1464, 1473, 1502, 1539, 1544, 1654, 1677, 1699, 1838, 1848, 1874, 1898, 1944, 1951, 1971, 2016, 2035, 2139, 2184, 2273, 2278, 2422, 2454, 2514, 2532, 2558, 2611, 2653, 2673, 2751, 2780, 2792, 2974, 3041, 3053, 3200, 3204, 3218, 3228, 3242, 3291, 3303, 3313, 3340, 3358, 3391, 3474, 3506, 3528, 3712, 3810, 3819, 3833, 3892, 3930, 4100, 4212, 4223, 4255, 4263, 4304], 'appears': [10, 209, 472], 'to': [11, 114, 145, 174, 182, 210, 313, 344, 373, 381, 453, 467, 473, 506, 541, 734, 736, 753, 799, 849, 952, 1107, 1133, 1268, 1291, 1579, 1590, 1649, 1788, 1823, 1853, 1865, 2091, 2111, 2348, 2356, 2456, 2561, 2621, 2661, 2830, 2849, 2969, 2992, 3020, 3031, 3098, 3265, 3273, 3317, 3360, 3443, 3445, 3599, 3647, 3671, 3758, 3859, 3888, 3901, 4270, 4310], 'promote': [12, 211, 823, 1650], 'atherogenesis.': [13, 212], 'Intraplaque': [14, 213], 'CRP': [15, 38, 60, 72, 90, 107, 130, 166, 196, 214, 237, 259, 271, 289, 306, 329, 365, 395, 509, 538, 583, 627, 701, 729, 879, 1083, 1161, 1164, 1287, 1426, 1460, 1497, 1596, 1766, 1815, 1847, 1870, 2072, 2107, 2670, 2678, 2997, 3320, 3806], 'colocalizes': [16, 215, 880], 'with': [17, 85, 99, 112, 138, 216, 284, 298, 311, 337, 556, 563, 597, 881, 990, 1013, 1049, 1081, 1159, 1801, 2205, 2238, 2337, 2350, 2370, 2432, 2508, 2520, 2530, 2564, 2731, 2986, 3055, 3126, 3172, 3197, 3240, 3334, 3377, 3389, 3472, 3495, 3618, 3682, 3701, 3882, 3916, 3932, 4235, 4250, 4258, 4284], 'oxidized': [18, 217, 737, 755, 768, 808, 858, 2237, 2355], 'low': [19, 218, 738, 923, 1163, 1803, 2310, 2473], 'density': [20, 219, 739, 924, 2154, 2311, 2474], 'lipoprotein': [21, 220, 740, 2312, 2475, 3535], '(OxLDL)': [22, 221, 741], 'macrophages': [24, 83, 136, 172, 223, 282, 335, 371, 884, 927, 1248, 2435, 2753, 3349, 3578, 3768], 'human': [26, 86, 165, 225, 285, 364, 680, 716, 886, 1223, 1341, 1467, 1506, 1549, 1595, 1940, 2026, 2118, 2168, 2314, 2386, 2426, 2433, 2443, 2566, 2572, 3413, 3813, 4276, 4315, 4346], 'lesions.': [28, 227], 'Matrix': [29, 228], 'metalloproteinase-9': [30, 229, 985, 1007, 1046, 1338], '(MMP-9)': [31, 230, 1008], 'has': [32, 231, 621, 730, 874, 1288, 1598, 2826, 4282, 4307], 'been': [33, 51, 232, 250, 622, 732, 875, 1289, 1599, 1615, 1851, 2827, 4308], 'implicated': [34, 233], 'plaque': [36, 183, 235, 382, 454, 553, 590, 1429], 'rupture.': [37, 236, 455], 'promotes': [39, 238, 511, 530, 635, 662, 1635, 4336], 'OxLDL': [40, 62, 75, 105, 169, 239, 261, 274, 304, 368, 882, 1849, 1872, 2367, 2407, 2691, 2719, 3039, 3160, 3322, 3593, 3608], 'uptake': [41, 63, 76, 103, 121, 170, 240, 262, 275, 302, 320, 369, 825, 1873, 2424, 2536, 2720, 3040, 3323, 3628, 3718], 'MMP': [43, 179, 242, 378, 1245, 1300], 'induction': [44, 243], 'vitro;': [46, 245], 'however,': [47, 246], 'these': [48, 247, 1808, 1857], 'have': [49, 248, 1614, 1850], 'not': [50, 159, 249, 358, 1826, 2089, 2109, 2479, 3010, 3756], 'investigated': [52, 251, 3612], 'vivo.': [54, 253, 3325], 'We': [55, 254, 3610], 'examined': [56, 255, 3581], 'effect': [58, 257, 1386, 1541, 1593, 1791, 1813, 1868, 2252, 3614, 3763], 'of': [59, 104, 195, 258, 303, 394, 403, 408, 420, 449, 463, 554, 582, 631, 674, 704, 713, 762, 767, 802, 852, 916, 961, 983, 1005, 1041, 1043, 1089, 1101, 1112, 1127, 1272, 1295, 1299, 1308, 1348, 1378, 1387, 1425, 1537, 1542, 1564, 1575, 1584, 1594, 1682, 1770, 1792, 1814, 1842, 1869, 1901, 2008, 2045, 2106, 2192, 2215, 2222, 2253, 2309, 2335, 2405, 2468, 2498, 2600, 2636, 2639, 2646, 2714, 2725, 2737, 2749, 2776, 2800, 2813, 2815, 2841, 2847, 2902, 2965, 2967, 2979, 2996, 3002, 3048, 3072, 3079, 3090, 3096, 3123, 3143, 3155, 3183, 3187, 3207, 3230, 3247, 3256, 3271, 3281, 3310, 3368, 3394, 3399, 3435, 3463, 3532, 3553, 3573, 3587, 3615, 3761, 3772, 3841, 3905, 3953, 3961, 4040, 4074, 4107, 4169, 4174, 4206, 4261], 'on': [61, 260, 1546, 1798, 1807, 1818, 1871, 2051, 2256, 2604, 2733, 2743, 3068, 3149, 3352, 3525, 3626, 3764, 3927, 3942, 4079, 4198, 4210], 'MMP-9': [65, 133, 264, 332, 1090, 1103, 1129, 1156, 1250, 1843, 1875, 3042, 3765, 3836, 3967, 4217, 4220], 'production': [66, 265, 630, 703, 1339], 'vivo': [68, 190, 267, 389, 1577, 1817, 2688, 4059], 'Wistar': [70, 269, 2578], 'rats.': [71, 270, 2716], 'significantly': [73, 92, 272, 291, 549], 'increased': [74, 93, 102, 132, 273, 292, 301, 331, 1010], 'peritoneal': [79, 278, 2712, 2752, 2804, 2817, 3348, 3767], 'sterile': [81, 280, 2675, 2682, 3024, 3063, 3124], 'pouch': [82, 281, 2676, 2823, 2845, 2905, 3025, 3045, 3094, 3141, 3170, 3189, 3211, 3259, 3261, 3277, 3295, 3577, 3595, 3713, 3723, 3974, 4180, 4294], 'compared': [84, 98, 137, 283, 297, 336, 2985, 3617], 'serum': [87, 286, 1044, 1941], 'albumin': [88, 287, 1942], '(huSA).': [89, 288], 'also': [91, 290, 510, 731, 1149, 1845, 3580, 3694, 4268], 'intracellular': [94, 293, 3436, 3583], 'cholesteryl': [95, 294, 3437, 3554, 3584], 'ester': [96, 295, 1928, 3438, 3585, 4078], 'accumulation': [97, 296, 3380, 3552], 'huSA.': [100, 299], 'The': [101, 300, 1605, 1985, 1998, 2103, 2213, 2251, 2402, 2450, 2540, 2617, 2628, 2739, 2797, 2878, 2900, 2939, 3062, 3174, 3185, 3202, 3235, 3279, 3489, 3551, 3567, 3732, 3749, 3853, 3908, 3937, 3976, 4179, 4238, 4289], 'by': [106, 110, 122, 143, 171, 305, 309, 321, 342, 370, 585, 682, 715, 1093, 1209, 1794, 2031, 2152, 2196, 2219, 2303, 2425, 2445, 2476, 2537, 2632, 2747, 3119, 3181, 3192, 3299, 3386, 3536, 3558, 3629, 3743, 4172, 4233, 4298], 'was': [108, 141, 307, 340, 1863, 1892, 1982, 1992, 2002, 2023, 2144, 2194, 2217, 2236, 2346, 2354, 2368, 2412, 2630, 2692, 2708, 2728, 2806, 3136, 3166, 3297, 3384, 3482, 3556, 3597, 3693, 3719, 3747, 3844, 3864, 3910, 3939, 3947, 4161, 4241, 4248, 4296], 'inhibited': [109, 308], 'pretreatment': [111, 310], 'antibodies': [113, 312, 1958, 3643, 3750], 'CD32,': [115, 314, 1949, 3648], 'CD64,': [116, 315, 3649, 3661], 'CD36,': [117, 316, 1950, 3650], 'fucoidin,': [119, 318, 3685], 'suggesting': [120, 319], 'both': [123, 322, 754], 'scavenger': [124, 323, 3687], 'receptors': [125, 324], 'Fc-γ': [127, 326], 'receptors.': [128, 327], 'Furthermore,': [129, 328, 1740], 'treatment': [131, 330, 1769], 'activity': [134, 333, 1503, 2000, 2404, 4313], 'huSA,': [139, 338], 'which': [140, 339, 2912, 4247], 'abrogated': [142, 341], 'inhibitors': [144, 343, 3785, 4043], 'p38': [146, 345, 1911, 4101], 'mitogen-activated': [147, 346, 1912], 'kinase,': [149, 348], 'extracellular': [150, 349, 1379, 1419, 1919], 'signal-regulated': [151, 350, 1420, 1920], 'kinase': [152, 162, 351, 361, 1421, 1914, 1921, 1937, 4103], '(ERK),': [153, 352], 'nuclear': [155, 354], 'factor': [156, 355, 643, 3288], '(NF)-κB': [157, 356], 'but': [158, 357, 1844, 2478, 3013, 4142], 'Jun': [160, 359, 1935], 'N-terminal': [161, 360, 1936], '(JNK)': [163, 362, 1938], 'before': [164, 363, 3678], 'treatment.': [167, 366], 'Because': [168, 367], 'contributes': [173, 181, 372, 380], 'foam': [175, 374, 3423, 3538], 'cell': [176, 375, 830, 1334, 1833, 3311, 3424, 3574, 3842, 4194], 'formation': [177, 376, 960, 2901, 3154, 3531, 4039], 'release': [180, 379, 677, 1294, 1876, 3280], 'instability,': [184, 383], 'this': [185, 384, 3328, 4280], 'study': [186, 385, 1862, 2970], 'provides': [187, 386, 2906], 'novel': [188, 387], 'evidence': [191, 390, 399, 2114], 'for': [192, 391, 1345, 1471, 1767, 1882, 2014, 2282, 2505, 2534, 2625, 2648, 2699, 2718, 2794, 3254, 3362, 3418, 3452, 3582, 3817, 3835, 3885, 3965, 4057, 4186, 4200, 4208, 4216], 'role': [194, 393, 1088, 2775, 3417], 'atherosclerosis.': [198, 397], 'Increasing': [398], 'supports': [400], 'involvement': [402, 1427], 'inflammation': [404, 423, 2848, 3097], 'pathogenesis': [407], 'atherosclerosis': [409, 441, 479], 'acute': [411, 934, 1050, 1686], 'coronary': [412, 587, 992, 1134, 1658], 'syndromes': [413], '(ACSs)': [414], '(1.Croce': [415], 'K.': [416, 570, 696, 1022, 1371, 1375], 'Libby': [417, 1456, 3802], 'P.': [418, 1457, 2294, 3803], 'Intertwining': [419], 'thrombosis': [421], 'atherosclerosis.Curr.': [425], 'Opin.': [426], 'Hematol.': [427], '2007;': [428, 2124, 2892, 2953, 3543], '14:': [429], '55-61Crossref': [430], 'PubMed': [431, 497, 613, 687, 724, 777, 817, 867, 942, 1071, 1142, 1190, 1237, 1281, 1359, 1393, 1437, 1482, 1522, 1558, 1694, 1733, 1775, 2061, 2132, 2181, 2268, 2327, 2399, 2489, 2859, 2895, 2956, 3108, 3430, 3546, 3828, 4088, 4116, 4153], 'Scopus': [432, 498, 614, 688, 725, 778, 818, 868, 943, 1000, 1072, 1143, 1191, 1238, 1282, 1360, 1394, 1438, 1483, 1523, 1559, 1695, 1734, 1776, 2133, 2269, 2328, 2490, 2896, 2957, 3431, 3547, 3829, 4089, 4117, 4154], '(231)': [433], 'Google': [434, 500, 535, 616, 667, 690, 727, 780, 820, 870, 945, 1002, 1074, 1145, 1193, 1240, 1284, 1362, 1396, 1440, 1485, 1525, 1561, 1640, 1697, 1736, 1778, 2062, 2135, 2182, 2271, 2330, 2400, 2492, 2790, 2860, 2898, 2959, 3109, 3433, 3549, 3831, 4091, 4119, 4156, 4341], 'Scholar).': [435, 501, 536, 617, 728, 871, 1003, 1146, 1194, 1285, 1641, 2063, 2331, 2401, 2493, 2899, 3550, 4157], 'Monocyte/macrophages': [436], 'are': [437, 504, 950, 1009, 1105, 1206, 1679, 1830, 2088, 2108, 2542, 3306, 3569, 4105], 'pivotal': [438], 'cells': [439, 759, 1211, 1303, 2438, 2451, 2527, 2568, 2801, 3208, 3232, 3236, 3372, 3383, 3440, 3467, 3490, 3630, 3724, 4318], 'participate': [443], 'all': [445, 1563, 2686], 'stages,': [446], 'from': [447, 678, 1247, 1301, 1886, 1893, 1906, 1947, 1961, 1983, 1993, 2003, 2025, 2115, 2146, 2149, 2441, 2569, 2585, 2768, 2998, 3114, 3457, 3492, 3564, 3770], 'initiation': [448], 'fatty': [451], 'streak': [452], 'C-': [456], 'reactive': [457, 638, 919], '(CRP),': [459], 'prototypic': [461], 'marker': [462, 489], 'inflammation,': [464], 'addition': [466], 'being': [468], 'a': [469, 763, 1078, 1086, 1152, 1573, 1802, 2046, 2357, 2593, 2605, 2681, 2963, 3076, 3127, 3245, 3502, 3686, 3870, 3928, 3943, 3950, 3957, 3973, 4244, 4299], 'risk': [470, 488], 'marker,': [471], 'be': [474, 542, 953, 1824, 1854, 2916], 'an': [475, 522, 654, 1423, 1600, 1627, 1785, 2300, 2597, 2903, 2907, 3080, 4328], 'active': [476], 'participant': [477], '(2.Jialal': [480], 'I.': [481, 518, 650, 698, 1170, 1443, 1490, 1623, 2102, 2160, 2162, 2246, 2378, 2380, 2464, 3789, 4064, 4324], 'Devaraj': [482, 515, 647, 1620, 2096, 4321], 'S.': [483, 514, 516, 646, 648, 1030, 1124, 1166, 1317, 1619, 1621, 2097, 2158, 2296, 2376, 3521, 4320, 4322, 4361], 'Venugopal': [484], 'S.K.': [485], 'protein:': [487], 'or': [490, 525, 599, 657, 1630, 3651, 3656, 3698, 3751, 4159, 4331], 'mediator': [491], 'atherothrombosis?.Hypertension.': [493], '2004;': [494, 1434, 1555, 1730, 3427], '44:': [495], '6-11Crossref': [496], '(495)': [499], 'Much': [502], 'data': [503, 1578, 1606, 2084], 'accumulating': [505], 'suggest': [507], 'that': [508, 624, 877, 957, 1097, 2067, 2085, 2349, 2994, 3480], 'atherothrombosis': [512], '(3.Verma': [513, 645, 1618, 4319], 'Jialal': [517, 649, 1169, 1622, 2101, 2161, 2379, 4323], 'Is': [519, 651, 1624, 4325], 'innocent': [523, 655, 1628, 4329], 'bystander': [524, 656, 1629, 4330], 'proatherogenic': [526, 658, 1631, 4332], 'culprit?': [527, 659, 1632, 4333], 'atherothrombosis.Circulation.': [531, 663, 1636, 4337], '2006;': [532, 664, 939, 1063, 1390, 1479, 1637, 1772, 3825, 4338], '113:': [533, 665, 1638, 4339], '2135-2150PubMed': [534, 666, 1639, 4340], 'Also,': [537, 1085, 1286, 2234, 2717], 'known': [540, 3268], 'lesions': [546, 888, 1837], 'higher': [550], 'patients': [555, 596, 989, 1012, 1048], 'unstable': [557, 600, 931, 1054], 'angina': [558, 565, 601, 932, 1018, 1055, 1059], 'pectoris': [559, 566, 1056], 'than': [560], 'those': [562], 'stable': [564, 598, 929, 1058], '(4.Ishikawa': [567], 'T.': [568, 572, 580, 1026, 1034, 1319, 1323, 1367, 1369, 1373, 1672, 2863, 2924, 3408], 'Hatakeyama': [569], 'Imamura': [571], 'Shibata': [573], 'Y.': [574, 576, 578, 1032, 1407, 4066, 4128], 'Hikichi': [575], 'Asada': [577], 'Eto': [579], 'Involvement': [581], 'obtained': [584, 1885, 1960, 2148, 2584], 'directional': [586], 'atherectomy': [588], 'instability': [591], 'developing': [593, 3899], 'restenosis': [594], 'pectoris.Am.': [602, 1060], 'J.': [603, 996, 1061, 1215, 1445, 1455, 1530, 1664, 2784, 3791, 3801, 4145], 'Cardiol.': [604, 1062, 1478, 3824, 4112], '2003;': [605, 1139], '91:': [606], '287-292Abstract': [607], 'Full': [608, 610, 1066, 1068, 1232, 1234, 1354, 1356, 1517, 1519, 2058, 2127, 2129, 2176, 2178, 2322, 2324, 2394, 2396], 'Text': [609, 611, 1067, 1069, 1233, 1235, 1355, 1357, 1518, 1520, 2059, 2128, 2130, 2177, 2179, 2323, 2325, 2395, 2397], 'PDF': [612, 1070, 1236, 1358, 1521, 2060, 2131, 2180, 2326, 2398], '(94)': [615], 'To': [618, 3326, 3635, 3838], 'date,': [619], 'it': [620, 873, 1547, 3028], 'shown': [623, 4309], 'monocytes,': [626], 'induces': [628, 1332, 1461, 3807], 'inflammatory': [632, 675, 2075, 2832, 2889, 2913, 2950], 'cytokines': [633, 3283], 'monocyte': [636], 'chemotaxis,': [637], 'oxygen': [639], 'species,': [640], 'tissue': [642, 1683, 1899, 2909], 'expression': [644, 712, 1412, 1501, 1536, 2166, 2384], 'Scholar,': [668, 691, 781, 1363, 1397, 1441, 1486, 1526, 2861, 4092, 4120], '5.Ballou': [669], 'C.P.': [670], 'Lozanski': [671], 'G.': [672, 1168, 1488, 1496, 1534, 3410, 4126, 4349], 'Induction': [673], 'cytokine': [676], 'cultured': [679, 1505], 'monocytes': [681, 4347], 'CRP.Cytokine.': [683], '1992;': [684, 2855, 3104], '4:': [685], '361-368Crossref': [686], '(307)': [689], '6.Galve-de': [692], 'Rochemonteix': [693], 'B.': [694, 967, 1118, 2875, 2936, 4068, 4070], 'Wiktorowicz': [695], 'Kushner': [697], 'Dayer': [699], 'J.M.': [700], 'increases': [702, 1498, 1714], 'IL-1': [705, 707], 'alpha,': [706], 'beta,': [708], 'TNF-alpha': [710], 'mRNA': [714], 'alveolar': [717], 'macrophages.J.': [718, 2170, 2388], 'Leukoc.': [719], 'Biol.': [720, 813, 863, 1227, 1277, 1433, 2053, 2264, 2317, 2786, 3542], '1993;': [721], '53:': [722], '439-445Crossref': [723], '(109)': [726], 'reported': [733, 876, 1151, 1290, 1648, 1852], 'bind': [735, 798, 848], '(7.Chang': [742], 'M.K.': [743], 'Binder': [744], 'C.J.': [745, 1217, 2248], 'Torzewski': [746], 'M.': [747, 890, 1038, 1213, 1313, 1325, 1329, 1494, 1662, 1670, 2865, 2926, 4351, 4355, 4363], 'Witztum': [748], 'J.L.': [749], 'binds': [752], 'LDL': [756, 2141, 2193, 2199, 2235, 2257, 2353, 2420], 'apoptotic': [758], 'through': [760, 1416, 2186], 'recognition': [761], 'common': [764], 'ligand:': [765], 'phosphorylcholine': [766], 'phospholipids.Proc.': [769], 'Natl.': [770], 'Acad.': [771], 'Sci.': [772, 1389], 'USA.': [773], '2002;': [774, 4085], '99:': [775], '13043-13048Crossref': [776], '(430)': [779], '8.Van': [782], 'Tits': [783, 833], 'L.': [784, 834, 1260, 1405, 1492, 2043, 3406], 'Graaf': [785, 835], 'J.de': [786, 836], 'Toenhake': [787, 837], 'H.': [788, 838, 1028, 1036, 1315, 1321, 3517], 'Heerde': [789, 839], 'W.Van': [790, 840], 'Stalenhoef': [791, 841], 'A.': [792, 842, 969, 1024, 1122, 1311, 2869, 2930, 4072, 4359, 4367], 'annexin': [796, 846], 'A5': [797, 847], 'distinct': [800, 850], 'sites': [801, 851], 'negatively': [803, 853], 'charged': [804, 854], 'phospholipids': [805, 855], 'low-density': [809, 859], 'lipoprotein.Arterioscler.': [810, 860], 'Thromb.': [811, 861, 1431, 2262, 3540], 'Vasc.': [812, 862, 1432, 2263, 3541], '2005;': [814, 864, 997, 1187, 1514, 4150], '25:': [815, 865], '717-722Crossref': [816, 866], '(63)': [819, 869, 1192], 'Scholar)': [821, 1075, 1698, 1737, 1779, 2183, 2272, 2791, 3110, 3832, 4342], 'its': [824, 2074, 2663, 3387, 3906], 'monocyte/macrophage-like': [828], 'U937': [829, 1414], 'line': [831], '(8.Van': [832], 'Importantly,': [872, 1195], 'intraplaque': [878, 917], '(9.Meuwissen': [889], 'Van': [891, 902], 'der': [892, 903], 'Wal': [893], 'A.C.': [894], 'Niessen': [895], 'H.W.': [896], 'Koch': [897], 'K.T.': [898], 'De': [899], 'Winter': [900], 'R.J.': [901], 'Loos': [904], 'C.M.': [905], 'Rittersma': [906], 'S.Z.': [907], 'Chamuleau': [908], 'S.A.': [909], 'Tijssen': [910], 'J.G.': [911], 'Becker': [912], 'A.E.': [913], 'et': [914, 1039, 1742, 1764], 'al.Colocalisation': [915], 'C': [918, 1220], 'protein,': [920], 'complement,': [921], 'oxidised': [922], 'lipoprotein,': [925], 'myocardial': [935, 1051, 1651, 1687], 'infarction.J.': [936, 1688], 'Clin.': [937, 1184, 1512, 2484], 'Pathol.': [938], '59:': [940], '196-201Crossref': [941], '(79)': [944], 'Scholar).Plaque': [946], 'rupture': [947], 'erosion': [949], 'believed': [951], 'key': [955], 'events': [956, 3035], 'trigger': [958], 'thrombus': [962], 'subsequent': [964], 'ACSs': [965], '(10.Zeng': [966], 'Prasan': [968], 'Fung': [970], 'K.C.': [971], 'Solanki': [972], 'V.': [973, 1755, 4357, 4365], 'Bruce': [974], 'D.': [975, 979, 1020], 'Freedman': [976], 'S.B.': [977], 'Brieger': [978], 'Elevated': [980], 'circulating': [981], 'levels': [982, 1042, 1180, 2018], 'matrix': [984, 1006, 1045, 1263, 1337, 1380, 1462, 1499, 3808], '-2': [987], 'symptomatic': [991], 'artery': [993, 1135, 1659, 1701, 1721], 'disease.Int.': [994], 'Med.': [995, 1138, 1513, 1690], '35:': [998], '331-335Crossref': [999], '(84)': [1001], 'Levels': [1004], 'heart': [1014], 'failure': [1015], 'ACS/unstable': [1017], '(11.Fukuda': [1019], 'Shimada': [1021], 'Tanaka': [1023], 'Kusuyama': [1025], 'Yamashita': [1027], 'Ehara': [1029], 'Nakamura': [1031], 'Kawarabayashi': [1033], 'Iida': [1035], 'Yoshiyama': [1037], 'al.Comparison': [1040], 'infarction': [1052], 'versus': [1053, 1057, 1162], '97:': [1064], '175-180Abstract': [1065], '(107)': [1073], 'exhibit': [1077], 'strong': [1079], 'correlation': [1080], 'high': [1082, 1160, 1176, 2769], 'levels.': [1084], 'causal': [1087], 'supported': [1092], 'genetic': [1094], 'studies': [1095], 'showing': [1096], 'functional': [1098], 'promoter': [1099], 'variations': [1100], 'gene': [1104, 1130], 'related': [1106], 'presence': [1109], 'severity': [1111, 2880, 2941], 'cardiovascular': [1113], 'disease': [1114], '(12.Morgan': [1115], 'A.R.': [1116], 'Zhang': [1117, 1400], 'Tapper': [1119], 'W.': [1120, 1532], 'Collins': [1121], 'Ye': [1123], 'Haplotypic': [1125], 'analysis': [1126], 'relation': [1132], 'disease.J.': [1136], 'Mol.': [1137, 1276], '81:': [1140], '321-326Crossref': [1141], '(108)': [1144], 'Our': [1147], 'group': [1148, 3991, 3994, 3997, 4006, 4015, 4024], 'earlier': [1150], 'significant': [1153], 'increase': [1154], 'subjects': [1158], '(13.Devaraj': [1165], "O'Keefe": [1167], 'Defining': [1171], 'proinflammatory': [1173, 1582, 3269], 'phenotype': [1174], 'using': [1175, 2189, 2448, 2511, 3075, 3511, 3725, 3972, 4203, 4213, 4273], 'sensitive': [1177], 'as': [1181, 1784, 1953, 1955, 2029, 2372, 2460, 2544, 2756, 2962, 3007, 3015, 3403, 3501, 3710, 3736, 3786, 3949, 3989, 4052, 4189, 4227, 4243, 4279, 4287, 4343, 4345], 'biomarker.J.': [1183], 'Endocrinol.': [1185], 'Metab.': [1186, 1729], '90:': [1188], '4549-4554Crossref': [1189], 'MMP-1': [1196, 1411], '(a': [1197, 1200, 1204, 1251], 'collagenase),': [1198], 'MMP-2': [1199, 1897, 4262, 4272, 4275, 4286], 'gelatinase),': [1201], 'MMP-3': [1203], 'stromelysin)': [1205], 'predominantly': [1207], 'secreted': [1208, 1246], 'endothelial': [1210, 1224, 1333, 1468, 1551, 2120, 3814, 4317], '(14.Nguyen': [1212], 'Arkell': [1214], 'Jackson': [1216], 'Activated': [1218], 'directly': [1221, 3138], 'activates': [1222], 'gelatinase': [1225], 'A.J.': [1226, 2837, 3086], 'Chem.': [1228, 2054, 2318], '2000;': [1229, 1278, 2319], '275:': [1230, 2320], '9095-9098Abstract': [1231], '(83)': [1239], 'Scholar),': [1241, 2960], 'whereas': [1242], 'major': [1244], 'gelatinase)': [1252], '(15.Winberg': [1253], 'J.O.': [1254], 'Kolset': [1255], 'S.O.': [1256], 'Berg': [1257], 'E.': [1258], 'Uhlin-Hansen': [1259], 'Macrophages': [1261, 1821], 'secrete': [1262], 'metalloproteinase': [1264, 1381], '9': [1265], 'covalently': [1266], 'linked': [1267], 'core': [1270], 'chondroitin': [1273], 'sulphate': [1274], 'proteoglycans.J.': [1275], '304:': [1279], '669-680Crossref': [1280], '(78)': [1283], 'induce': [1292, 4311], 'various': [1296, 3282, 4042], 'different': [1297, 2419, 2644], 'forms': [1298], 'involved': [1304, 3036, 3605], 'process': [1307], 'atherogenesis': [1309, 2772], '(16.Nabata': [1310], 'Kuroki': [1312], 'Ueba': [1314], 'Hashimoto': [1316], 'Umemoto': [1318], 'Wada': [1320], 'Yasu': [1322], 'Saito': [1324], 'Momomura': [1326], 'S.I.': [1327], 'Kawakami': [1328], 'apoptosis': [1335], 'mononuclear': [1342, 2567], 'cells:': [1343, 1469, 3815], 'implications': [1344, 1470, 3816], 'destabilization': [1347], 'plaque.Atherosclerosis.': [1350], '2008;': [1351], '196:': [1352], '129-135Abstract': [1353], '(70)': [1361], '17.Abe': [1364], 'N.': [1365, 1447, 3793, 4062], 'Osanai': [1366], 'Fujiwara': [1368], 'Kameda': [1370], 'Matsunaga': [1372], 'Okumura': [1374], 'CRP-induced': [1376, 1535, 3966], 'upregulation': [1377], 'inducer': [1382], 'macrophages:': [1384], 'inhibitory': [1385], 'fluvastatin.Life': [1388], '78:': [1391], '1021-1028Crossref': [1392], '(48)': [1395], '18.Williams': [1398], 'T.N.': [1399], 'C.X.': [1401], 'Game': [1402], 'B.A.': [1403, 2250], 'He': [1404], 'Huang': [1406], 'stimulates': [1410], 'histiocytes': [1415], 'Fc[gamma]RII': [1417], 'pathway:': [1422], 'implication': [1424], 'destabilization.Arterioscler.': [1430], '24:': [1435, 1731], '61-66Crossref': [1436], '(105)': [1439], '19.Montero': [1442], 'Orbe': [1444, 3790], 'Varo': [1446, 3792], 'Beloqui': [1448, 3794], 'O.': [1449, 3795], 'Monreal': [1450, 3796], 'J.I.': [1451, 2286, 3797], 'Rodríguez': [1452, 3798], 'J.A.': [1453, 1459, 1706, 1761, 3799, 3805], 'Díez': [1454, 3800], 'Páramo': [1458, 3804], 'metalloproteinase-1': [1463, 1902, 3809], '-10': [1465, 3811], 'clinical': [1472, 3818], 'subclinical': [1474, 3820], 'atherosclerosis.J.': [1475, 3821], 'Am.': [1476, 3822], 'Coll.': [1477, 3823], '47:': [1480, 3826], '1369-1378Crossref': [1481, 3827], '(161)': [1484, 3830], '20.Doronzo': [1487], 'Russo': [1489], 'Mattiello': [1491], 'Trovati': [1493], 'Anfossi': [1495], 'metalloproteinase-2': [1500], 'vascular': [1507, 1550], 'smooth': [1508], 'muscle': [1509], 'cells.J.': [1510, 2121], 'Lab.': [1511], '146:': [1515], '287-298Abstract': [1516], '(32)': [1524], '21.Lin': [1527], 'R.': [1528, 1704], 'Liu': [1529], 'Gan': [1531], 'Yang': [1533], 'CD40-CD40L': [1538], 'lovastatin': [1543], 'fenofibrate': [1545], 'cells.Biol.': [1552], 'Pharm.': [1553], 'Bull.': [1554], '27:': [1556, 3544], '1537-1543Crossref': [1557], '(55)': [1560], 'Scholar).Despite': [1562], 'vitro': [1567], 'reports': [1568], 'cited': [1569], 'above,': [1570], 'there': [1571, 3481], 'paucity': [1574], 'support': [1580], 'effects': [1583, 1797, 2076, 2087, 2105, 2664, 3270], 'CRP.': [1585, 3173], 'A': [1586, 2259, 2811, 3522], 'valid': [1587], 'animal': [1588, 2622, 2634], 'model': [1589, 1787, 2825, 2846, 2919, 3095, 3596, 3775], 'test': [1591, 1789, 2651], '(hCRP)': [1597], 'issue': [1601], 'literature.': [1604], 'concerning': [1607], 'hCRP': [1608, 1643, 1793, 2649, 3272, 3616, 3679, 4160], 'transgene': [1609], 'apolipoprotein': [1611], 'E-deficient': [1612], 'mice': [1613], 'largely': [1616], 'inconsistent': [1617], 'However,': [1642], 'administration': [1644, 2647, 2966, 2978], 'rats': [1646, 2579, 2618, 2658, 2740, 3050, 3074, 3175, 3339, 3493, 3623, 3669, 3771, 3977, 3986, 4175], 'infarct': [1652, 1656, 1716, 1799], 'size': [1653, 1717, 1800], 'cerebral': [1655, 1700, 1715, 1720], 'ligation': [1660], '(22.Griselli': [1661], 'Herbert': [1663], 'Hutchinson': [1665], 'W.L.': [1666], 'Taylor': [1667], 'K.M.': [1668], 'Sohail': [1669], 'Krausz': [1671], 'Pepys': [1673, 1709, 1741], 'M.B.': [1674, 1710, 1745], 'complement': [1678], 'important': [1680, 1825, 2991], 'mediators': [1681], 'damage': [1684], 'Exp.': [1689, 2785], '1999;': [1691], '190:': [1692], '1733-1740Crossref': [1693], '(446)': [1696], 'occlusion': [1702, 1722], '(23.Gill': [1703], 'Kemp': [1705], 'Sabin': [1707], 'C.': [1708], 'Human': [1711], 'after': [1718, 3153, 4037, 4166], 'middle': [1719], 'adult': [1724], 'rats.J.': [1725], 'Cereb.': [1726], 'Blood': [1727], 'Flow': [1728], '1214-1218Crossref': [1732], '(123)': [1735], 'models,': [1738], 'respectively.': [1739, 1978], 'al.': [1743], '(24.Pepys': [1744], 'Hirschfield': [1746], 'G.M.': [1747], 'Tennent': [1748], 'G.A.': [1749], 'Gallimore': [1750], 'J.R.': [1751, 2288], 'Kahan': [1752], 'M.C.': [1753], 'Bellotti': [1754], 'Hawkins': [1756], 'P.N.': [1757], 'Ley': [1758], 'S.V.': [1759], 'Aquilina': [1760], 'Robinson': [1762], 'C.V.': [1763], 'al.Targeting': [1765], 'CVD.Nature.': [1771], '440:': [1773], '1217-1221Crossref': [1774], '(559)': [1777], 'recently': [1780], 'validated': [1781], 'rat': [1783, 1819, 2843, 3092, 4137, 4259, 4285], 'appropriate': [1786], 'blocking': [1795, 3642], "CRP's": [1796, 3762], 'molecular': [1804], 'weight': [1805, 2698], 'inhibitor.Based': [1806], 'data,': [1809], 'we': [1810, 2065, 3018, 3330], 'explored': [1811], 'macrophages.': [1820, 3234], 'appear': [1822], 'only': [1827, 3011, 3497], 'because': [1828, 1846, 3027], 'they': [1829], 'predominant': [1832], 'type': [1834, 3590, 3604, 3640], 'main': [1840], 'source': [1841], 'colocalized': [1855], 'cells.': [1858, 2551, 2810, 3740], 'Thus,': [1859, 3017], 'designed': [1864], 'investigate': [1866, 3032], 'vivo.MATERIALS': [1878], 'AND': [1879], 'METHODSGelatin': [1880], 'gels': [1881, 3876, 4211], 'zymography': [1883, 3861, 4188], 'were': [1884, 1905, 1946, 1959, 2012, 2019, 2429, 2439, 2452, 2501, 2528, 2554, 2583, 2590, 2613, 2619, 2659, 2741, 2754, 3051, 3066, 3176, 3190, 3233, 3237, 3263, 3350, 3373, 3441, 3468, 3509, 3579, 3665, 3705, 3715, 3734, 3755, 3776, 3856, 3877, 3970, 3978, 4044, 4184, 4196, 4267], 'Invitrogen.': [1887], 'Coomassie': [1888, 3918], 'Brilliant': [1889, 3919], 'Blue': [1890, 3920], 'R-250': [1891, 3921], 'Sigma': [1894], 'Chemical': [1895], 'Co.': [1896], 'inhibitor': [1900], '(TIMP-1)': [1903], 'ELISA': [1904, 3300, 4277], 'R&D': [1907], 'Biosystems.': [1908], 'SB203580': [1909, 3999], '[a': [1910, 1934], '(MAPK)': [1915], 'inhibitor],': [1916, 1924, 1939], 'PD098059': [1917, 4008], '[an': [1918], '(ERK)': [1922], '1/2': [1923], 'caffeic': [1925, 4075], 'acid': [1926, 4076], 'phenehthyl': [1927], '(CAPE)': [1929], '(an': [1930], 'NF-κB': [1931, 1999, 4305, 4312], 'inhibitor),': [1932], 'SP600125': [1933, 4017], '(huSA),': [1943], 'fucoidin': [1945, 3752], 'Sigma.': [1948], 'CD64': [1952], 'well': [1954, 4344], 'isotype': [1956], 'control': [1957, 2655], 'BD': [1962], 'Biosciences': [1963], '(San': [1964], 'Jose,': [1965], 'CA),': [1966, 1977], 'Cell': [1967, 3741], 'Sciences': [1968], '(Canton,': [1969], 'MA),': [1970], 'Santa': [1972], 'Cruz': [1973], 'Biotechnology': [1974], '(Santa': [1975], 'Cruz,': [1976], '2,2-Azobis-2-amidino-propane': [1979], 'dihydrochloride': [1980], '(AAPH)': [1981], 'WAKO.': [1984], 'fluorescent': [1986], 'probe': [1987], '1,1′-dioctadecyl-3,3,3′,3′': [1988], 'tetramethylindocarbocyanide': [1989], 'perchlorate': [1990], '(DiI)': [1991], 'Molecular': [1994], 'Probes': [1995], '(Eugene,': [1996], 'OR).': [1997], 'kit': [2001, 4281], 'Active': [2004], 'Motif': [2005], '(Carlsbad,CA).': [2006], 'All': [2007, 2552], 'reagents': [2010], 'used': [2011, 2408, 2660, 2793, 2828, 3264, 3598, 3754, 3834, 4185, 4242, 4269], 'tested': [2013], 'endotoxin,': [2015], '<0.06': [2020], 'ng/ml': [2021], 'consistently.hCRP': [2022], 'purified': [2024], 'ascitic/pleural': [2027], 'fluids': [2028, 3000], 'described': [2030, 2373, 2461, 2757, 3344, 3404, 3787, 4053, 4190], 'Du': [2032, 2098], 'Clos,': [2033], 'Zlock,': [2034], 'Marnell': [2036, 2042], '(25.Du': [2037], 'Clos': [2038, 2099], 'T.W.': [2039, 2100], 'Zlock': [2040], 'L.T.': [2041], 'Definition': [2044], 'binding': [2049], 'determinant': [2050], 'histones.J.': [2052], '1991;': [2055, 2486], '266:': [2056], '2167-2171Abstract': [2057], 'Recently,': [2064], 'showed': [2066], 'our': [2068, 2410], 'in-house': [2069], 'purified,': [2070], 'dialyzed': [2071], 'mediates': [2073], 'TLR4': [2078, 2116], 'knockdown': [2079, 2117], 'cells,': [2080, 3222], 'providing': [2081], 'further': [2082, 2795, 3636], 'cogent': [2083], 'CRP-mediated': [2086, 3038, 3159, 3592, 3607], 'attributable': [2090, 2110], 'endotoxin': [2092, 2112, 3008], 'contamination': [2093], '(26.Dasu': [2094], 'M.R.': [2095], 'biological': [2104], 'contamination:': [2113], 'aortic': [2119, 4316], 'Lipid': [2122, 2171, 2389], 'Res.': [2123, 2172, 2390, 3426, 4111], '48:': [2125], '509-512Abstract': [2126], '(60)': [2134], 'Scholar).LDL': [2136], 'preparation,': [2137], 'oxidation,': [2138], 'labelingNative': [2140], '(density,': [2142], '1.019–1.063)': [2143], 'isolated': [2145, 2440, 2755, 3347, 3491, 3769], 'plasma': [2147], 'healthy': [2150, 2442, 2571], 'donors': [2151], 'sequential': [2153], 'gradient': [2155], 'ultracentrifugation': [2156], '(27.Devaraj': [2157, 2375], 'Hugou': [2159, 2377], 'Alpha-tocopherol': [2163, 2381], 'decreases': [2164, 2382], 'CD36': [2165, 2383], 'monocyte-derived': [2169, 2387, 2427, 2434], '2001;': [2173, 2391, 2787, 4113], '42:': [2174, 2392], '521-527Abstract': [2175, 2393], 'desalted': [2185], 'Econopak': [2187], 'columns': [2188], 'PBS.': [2190, 3378], 'Oxidation': [2191], 'performed': [2195, 2431, 2555, 3341, 3971], 'incubating': [2197], 'native': [2198], '(1': [2200, 3448, 4000, 4018], 'mg': [2201], 'protein/ml)': [2202, 2518], 'at': [2203, 2503, 2596, 2641, 3111, 3244, 3396, 3675, 3866, 3879, 3895, 4049, 4163], '37°C': [2204, 2504, 3896], 'freshly': [2206], 'prepared': [2207, 2510], 'AAPH': [2208, 2690], '(5': [2209, 2241], 'mM': [2210], 'final': [2211], 'concentration).': [2212], 'extent': [2214, 2359], 'oxidation': [2216, 2336], 'determined': [2218, 3557], 'amount': [2221, 3563], 'thiobarbituric': [2223], 'acid-reactive': [2224], 'substances': [2225, 2980], '(28': [2226], '±': [2227, 2340, 2361, 2602], '8': [2228, 2283], 'nmol': [2229, 2342, 2363], 'malondialdehyde': [2230], '(MDA)': [2231], 'equivalents/mg': [2232, 2344, 2365], 'protein).': [2233, 2366], 'cupric': [2239], 'sulfate': [2240], 'μM': [2242], 'PBS)': [2244], '(28.Jialal': [2245], 'Fuller': [2247], 'Huet': [2249], 'alpha-tocopherol': [2254], 'supplementation': [2255, 2766], 'oxidation.': [2258], 'dose-response': [2260], 'study.Arterioscler.': [2261], '1995;': [2265], '15:': [2266], '190-198Crossref': [2267], '(341)': [2270], 'myeloperoxidase': [2274], '(MPO;': [2275], '30': [2276, 3886], 'nM)': [2277], 'water': [2279, 2612], '(100': [2280], 'μM)': [2281], 'h': [2284, 2507, 2607, 3454, 3677, 3708, 4165, 4177], '(29.Heller': [2285], 'Crowley': [2287], 'Hazen': [2289], 'S.L.': [2290], 'Salvay': [2291], 'D.M.': [2292], 'Wagner': [2293], 'Pennathur': [2295], 'Heinecke': [2297], 'J.W.': [2298], 'p-Hydroxyphenylacetaldehyde,': [2299], 'aldehyde': [2301], 'generated': [2302], 'myeloperoxidase,': [2304], 'modifies': [2305], 'phospholipid': [2306], 'amino': [2307], 'groups': [2308, 3982], 'intima.J.': [2316], '9957-9962Abstract': [2321], '(71)': [2329], 'Although': [2332], 'degree': [2334], 'copper': [2338], '(27': [2339], '5': [2341, 3622], 'MDA': [2343, 2364], 'protein)': [2345, 2656, 2727], 'similar': [2347], 'AAPH,': [2351, 2513], 'MPO-modified': [2352], 'lesser': [2358], '(15': [2360], '6': [2362], 'labeled': [2369], 'DiI': [2371, 2535, 3379], 'previously': [2374, 2462, 2758], 'specific': [2403, 3602, 4050, 4300], 'DiI-labeled': [2406], 'experiments': [2411, 2553, 3969], '13.1': [2413], 'μmol/mg': [2414], '(n': [2416, 3620, 3983], '=': [2417, 2703, 3621, 3984], '3': [2418, 3219], 'preparations).CRP': [2421], 'DiI-OxLDL': [2423, 2509, 2722, 3162, 3314, 3332, 3627, 3717], 'macrophagesExperiments': [2428], 'first': [2430, 3611], '(HMDMs).': [2436], 'Mononuclear': [2437], 'volunteers': [2444, 2573], 'density-gradient': [2446], 'centrifugation': [2447], 'Ficoll-Hypaque.': [2449], 'plated': [2453, 3351], 'allowed': [2455, 3359, 3442], 'differentiate': [2457], 'into': [2458, 2888, 2911, 2949, 3139, 3667, 3980, 4046], 'HMDMs': [2459, 2500], '(30.Jialal': [2463], 'Grundy': [2465], 'S.M.': [2466], 'Preservation': [2467], 'endogenous': [2470], 'antioxidants': [2471], 'ascorbate': [2477], 'probucol': [2480], 'during': [2481], 'oxidative': [2482], 'modification.J.': [2483], 'Invest.': [2485], '87:': [2487], '597-601Crossref': [2488], '(193)': [2491], 'On': [2494, 4033], '7th': [2496], 'day': [2497, 2736, 2746, 3152, 3180, 4036], 'culture,': [2499], 'incubated': [2502, 3894], '24': [2506], 'copper,': [2512], 'MPO': [2515], '(50': [2516, 3163], 'μg': [2517, 2724, 3840, 4205], 'along': [2519, 2730, 3171, 3333, 3681], 'huSA/hCRP': [2521], '(25': [2522, 3133], 'μg/ml).': [2523], 'After': [2524, 3873], 'incubation,': [2526, 3370, 3465], 'washed': [2529, 3238, 3374, 3469, 3878], 'PBS': [2531, 3241, 3473], 'analyzed': [2533], 'flow': [2538, 3726], 'cytometry.': [2539], 'results': [2541, 3305, 3568, 3733], 'expressed': [2543, 3307, 3570, 3735], 'mean': [2545], 'fluorescence': [2546, 3395], 'intensity': [2547], '(MFI)': [2548], 'per': [2549, 2574, 3308, 3571, 3624, 3673, 3738, 3987], '105': [2550, 3250, 3739], 'duplicate': [2557, 3456], 'repeated': [2559], 'three': [2560, 2570], 'five': [2562, 3672], 'times': [2563, 3376, 3471], 'pooled': [2565], 'experiment.Animal': [2575], 'treatmentMale': [2576], 'hooded': [2577], '(weighing': [2580], '125–150': [2581], 'g)': [2582], 'Charles': [2586], 'River': [2587], 'Laboratories.': [2588], 'Animals': [2589], 'housed': [2591], 'controlled': [2594], 'environment': [2595], 'ambient': [2598], 'temperature': [2599, 3881], '21': [2601], '2°C': [2603], '12': [2606], 'light/dark': [2608], 'cycle.': [2609], 'Food': [2610], 'provided': [2614], 'ad': [2615], 'libitum.': [2616], 'acclimatized': [2620], 'housing': [2623], 'conditions': [2624], '1': [2626, 3248], 'week.': [2627], 'protocol': [2629, 3082], 'approved': [2631], 'committee': [2635], 'University': [2638], 'California': [2640], 'Davis.': [2642], 'Two': [2643], 'routes': [2645], '(hCRP': [2650], 'huSA': [2654, 3619, 4158], 'examine': [2662, 2831, 3266, 3318], 'vivo:': [2666], 'i)': [2667], 'intraperitoneal': [2668, 2987, 3774], 'model,': [2669, 2677, 3026], 'administered': [2671, 2679], 'intraperitoneally;': [2672], 'ii)': [2674], 'air': [2683, 2822, 2844, 2904, 3044, 3064, 3093, 3125, 3258, 3276], 'pouch.': [2684, 3157, 3634], 'For': [2685, 3158], 'experiments,': [2689, 2721, 3161], 'used.Intraperitoneal': [2693], 'modelhCRP/huSA': [2694], '(20': [2695, 4182], 'mg/kg': [2696, 4001, 4010, 4019, 4028], 'body': [2697, 4002, 4011, 4020, 4029], '2': [2700, 3363, 3453, 3676, 4164], 'days,': [2701], 'n': [2702], '4': [2704, 3985], 'each': [2706, 3458], 'group)': [2707, 3625, 3674, 3988], 'injected': [2709, 2729, 3137, 3167, 3331, 3494, 3666, 3695, 4045, 4162], 'cavity': [2713, 2805, 2910], '(500': [2723], 'total': [2726, 2798, 2812, 3205, 3505, 3565], 'hCRP/huSA': [2732, 3132, 3335], '2nd': [2735], 'injection.': [2738], 'euthanized': [2742, 3177, 3706], '3rd': [2745, 3151, 4035], 'overdose': [2748, 3182], 'pentobarbital,': [2750], '(31.Kang': [2759], 'B.P.': [2760], 'Mehta': [2761], 'U.': [2762], 'Bansal': [2763], 'M.P.': [2764], 'Selenium': [2765], 'protects': [2767], 'fat': [2770], 'diet-induced': [2771], 'rats:': [2774], 'mitogen': [2777], 'stimulated': [2778], 'lymphocytes': [2779], 'macrophage': [2781, 3414, 3422, 3537], 'NO': [2782], 'production.Indian': [2783], '39:': [2788], '793-797PubMed': [2789], 'analysis.': [2796], 'number': [2799, 3206], '∼5–7': [2807], '×': [2808, 3220, 3249, 3449], '106': [2809, 3221, 3450], '75–80%': [2814], 'aspirate': [2818], 'contained': [2819], 'CD68-positive': [2820], 'cells.Sterile': [2821], 'modelThis': [2824], 'widely': [2829], 'responses': [2833], '(32.Davies': [2834, 3083], 'D.E.': [2835, 3084], 'Stevens': [2836, 3085], 'Houston': [2838, 3087], 'J.B.': [2839, 3088], 'Use': [2840, 3089], 'evaluate': [2850, 3099], 'regional': [2851, 3100], 'drug': [2852, 3101], 'delivery.Agents': [2853, 3102], 'Actions.': [2854, 3103], 'Spec': [2856, 3105], 'No:': [2857, 3106], 'C109-C111Crossref': [2858, 3107], '33.Laragione': [2862], 'Brenner': [2864, 2925], 'Yarlett': [2866, 2927], 'N.C.': [2867, 2928], 'Mello': [2868, 2929], 'Miller': [2870, 2931], 'E.J.': [2871, 2932], 'Metz': [2872, 2933], 'C.N.': [2873, 2934], 'Sherry': [2874, 2935], 'Gulko': [2876, 2937], 'P.S.': [2877, 2938], 'arthritis': [2879, 2940], 'quantitative': [2881, 2942], 'trait': [2882, 2943], 'locus': [2883, 2944], 'Cia7': [2884, 2945], 'regulates': [2885, 2946], 'neutrophil': [2886, 2947], 'migration': [2887, 2948], 'sites.Genes': [2890, 2951], 'Immun.': [2891, 2952], '8:': [2893, 2954], '147-153Crossref': [2894, 2955], '(5)': [2897, 2958], 'optimal': [2908], 'stimuli': [2914, 2968], 'can': [2915], 'introduced.': [2917], 'This': [2918], 'offers': [2920], 'several': [2921], 'advantages': [2922], '(33.Laragione': [2923], 'such': [2961, 3006], 'site': [2964], 'local': [2971], 'cellular': [2972], 'responses,': [2973], 'potentially': [2975], 'permits': [2976], 'much': [2982], 'lower': [2983], 'amounts': [2984], 'administration.': [2988], 'It': [2989], 'emphasize': [2993], 'isolation': [2995], 'pleural/ascitic': [2999], 'free': [3001, 3507, 3561], 'potent': [3003], 'interfering': [3004], 'contaminants': [3005], 'laborious': [3012], 'expensive': [3014], 'well.': [3016, 4288], 'chose': [3019], 'use': [3021, 4060], 'confined': [3023], 'cost-effective': [3030], 'mechanistic': [3034], 'production.Sterile': [3043], 'formationThe': [3046], 'backs': [3047], 'shaved': [3052], 'cleaned': [3054], 'alcohol': [3056], 'swabs': [3057], 'under': [3058, 3476], 'mild': [3059], 'isoflurane': [3060], 'sedation.': [3061], 'pouches': [3065, 4048], 'made': [3067, 3191], 'dorsal': [3070], 'surface': [3071], 'slight': [3077], 'modification': [3078], 'established': [3081], '∼1.5': [3112], 'inches': [3113], 'mid': [3116], 'neck': [3117], 'subcutaneously': [3118], 'injecting': [3120], '20': [3121, 4204], 'ml': [3122, 3217], '23': [3128], 'gauge': [3129], 'needle': [3130], 'syringe.': [3131], 'μg/ml': [3134, 3164, 3645, 3691], 'intrapouch)': [3135, 3165, 3646], 'cavities': [3142], 'lightly': [3144], 'restrained': [3145], '(hand-held)': [3146], 'conscious': [3147], 'animals': [3148], 'next': [3179], 'pentobarbital.': [3184], 'washouts': [3186], 'deflating': [3193], 'pouch,': [3195], 'irrigating': [3196], 'normal': [3198], 'saline,': [3199], 'aspiration.': [3201], 'volume': [3203], 'fluid': [3212, 3296], 'remained': [3213], 'fairly': [3214], 'constant': [3215], '(4–5': [3216], 'respectively)': [3223], 'over': [3224], 'time': [3226], 'period,': [3227], '76%': [3229], 'twice': [3239], 'resuspended': [3243], 'concentration': [3246, 4291], 'cells/ml': [3251], 'RPMI': [3253], 'analysis.Validation': [3255], 'modelThe': [3260], 'exudates': [3262, 3714, 4181, 4266, 4295], 'validate': [3274], 'model.': [3278, 3975], '[interleukin-1': [3284], '(IL-1),': [3285], 'tumor': [3286], 'necrosis': [3287], '(TNF),': [3289], 'IL-8,': [3290], 'IL-6]': [3292], 'measured': [3298, 3385, 3720, 4297], '(R&D': [3301], 'Systems),': [3302], 'milligram': [3309, 3572], 'protein.CRP': [3312], 'uptakeWe': [3315], 'aimed': [3316], 'whether': [3319], 'enhances': [3321, 3412], 'achieve': [3327], 'aim,': [3329], 'intraperitoneally': [3336], 'assays': [3343], 'below.Di-OxLDL': [3345], 'uptakeThe': [3346, 3594], '24-well': [3353], 'plates': [3354, 3447], '(1×': [3355], '104': [3356], 'cells)': [3357], 'adhere': [3361, 3444], 'h.': [3364], 'At': [3365, 3460], 'end': [3367, 3462], 'two': [3375, 3470], 'extraction': [3388, 3781], 'isopropanol': [3390], 'determination': [3393], 'excitation/emission': [3397], 'wavelengths': [3398], '532/564': [3400], 'nm,': [3401], 'respectively,': [3402], '(34.Li': [3405], 'Sawamura': [3407], 'Renier': [3409], 'Glucose': [3411], 'LOX-1': [3415, 3419], 'expression:': [3416], 'glucose-induced': [3421], 'formation.Circ.': [3425], '94:': [3428], '892-901Crossref': [3429], '(140)': [3432], 'Scholar).Analysis': [3434], 'accumulationThe': [3439], '12-well': [3446], 'cells/well)': [3451], 'rat.': [3459], 'air-dried': [3475], 'hood': [3478], 'so': [3479], 'no': [3483], 'residual': [3484], 'moisture': [3485], 'wells.': [3488], 'vehicle': [3496], '(no': [3498], 'OxLDL)': [3499], 'served': [3500], 'control.': [3503], 'Both': [3504], 'cholesterol': [3508, 3562], 'quantitated': [3510], 'gas': [3512], 'chromatography': [3513], '(35.Yancey': [3514], 'P.G.': [3515], 'Yu': [3516], 'Linton': [3518], 'M.F.': [3519], 'Fazio': [3520], 'pathway': [3523], 'dependent': [3524, 4141], 'apoE,': [3526], 'apoAI,': [3527], 'ABCA1': [3529], 'determines': [3530], 'buoyant': [3533], 'high-density': [3534], 'cells.Arterioscler.': [3539], '1123-1131Crossref': [3545], '(45)': [3548], 'esters': [3555], 'subtracting': [3559], 'cholesterol.': [3566], 'protein.': [3575], 'Additionally,': [3576, 3684, 4192], 'accumulation.Involvement': [3586], 'receptor': [3589, 3603, 3639, 4134], 'explore': [3600], 'uptake.': [3609], 'delineate': [3637], 'involved,': [3641], '(10': [3644, 3690], 'irrelevant': [3652], 'IgG': [3653, 4226, 4254], 'either': [3654, 3696], 'alone': [3655, 3697], 'combination': [3658, 3700], '(CD32': [3659], '+': [3660, 3663, 4004, 4013, 4022, 4031], 'CD32': [3662], 'CD36)': [3664], '(three': [3670], 'injection': [3680, 4168], 'DiI-OxLDL.': [3683], 'receptor-A': [3688], 'agonist': [3689], 'intrapouch),': [3692], 'anti-CD36': [3702], 'antibody.': [3703], 'Rats': [3704], '12–16': [3707, 4176], 'later': [3709], 'described,': [3711], 'collected.': [3716], 'cytometry': [3727], 'phycoerythrin': [3730], 'channel.': [3731], 'MFI': [3737], 'viability': [3742], 'trypan': [3744], 'blue': [3745, 3959], 'exclusion': [3746], '>90%.': [3748], 'concentrations': [3753, 4051], 'toxic': [3757], 'animals.Determination': [3760], 'productionThe': [3766], 'lysed': [3777], 'mammalian': [3779], 'reagent': [3782], 'including': [3783], 'protease': [3784], '(19.Montero': [3788], 'activity.': [3837], '10': [3839], 'lysates': [3843, 4195], 'added': [3845], '5×': [3846], 'SDS': [3847, 3891], 'sample': [3848], 'buffer': [3849, 3884, 3900], 'without': [3850], 'reducing': [3851], 'agent.': [3852], 'unheated': [3854], 'samples': [3855], 'then': [3857, 3940], 'applied': [3858], 'gelatin': [3860, 3955, 4187], 'gels.': [3862], 'Electrophoresis': [3863], 'run': [3865, 4197], '100': [3867], 'V': [3868], 'cold': [3871], 'room.': [3872], 'electrophoresis,': [3874], 'room': [3880], 'renaturing': [3883], 'min': [3887], 'remove': [3889], 'subsequently': [3893], 'overnight': [3897], 'allow': [3902], 'proteinase': [3903], 'digestion': [3904], 'substrate.': [3907], 'gel': [3909, 3938], 'rinsed': [3911], 'distilled': [3913], 'water,': [3914], 'stained': [3915, 3962], '0.25%': [3917], 'methanol-acetic': [3923, 3933], 'acid-water': [3924, 3934], '(30:10:60,': [3925], 'v/v/v)': [3926], 'shaker,': [3929], 'destained': [3931], '(10:10:80,': [3935], 'v/v/v).': [3936], 'photographed': [3941], 'light': [3944], 'box.': [3945], 'Proteolysis': [3946], 'detected': [3948, 4249], 'white': [3951], 'zone': [3952], 'digested': [3954], 'against': [3956], 'dark': [3958], 'background': [3960], 'gelatin.Mechanistic': [3963], 'insights': [3964], 'releaseThese': [3968], 'divided': [3979], 'six': [3981], 'follows:': [3990], '1,': [3992], 'huSA;': [3993], '2,': [3995], 'hCRP;': [3996, 4005, 4014, 4023], '3,': [3998], 'weight)': [4003, 4012, 4021, 4030], '4,': [4007], '(0.5': [4009], '5,': [4016], '6,': [4025], 'CAPE': [4026], '(0.2': [4027], 'hCRP.': [4032], 'pouches,': [4041], 'literature': [4056], '(36.Elmali': [4061], 'Ayan': [4063], 'Türköz': [4065], 'Mizrak': [4067], 'Germen': [4069], 'Bora': [4071], 'Effect': [4073], 'phenethyl': [4077], 'cartilage': [4080], 'experimental': [4082], 'osteoarthritis.Rheumatol.': [4083], 'Int.': [4084], '22:': [4086], '222-226Crossref': [4087], '(13)': [4090], '37.Fryer': [4093], 'R.M.': [4094, 4130], 'Hsu': [4095], 'A.K.': [4096], 'Gross': [4097], 'G.J.': [4098], 'ERK': [4099], 'MAP': [4102], 'activation': [4104], 'components': [4106], 'opioid-induced': [4108], 'delayed': [4109], 'cardioprotection.Basic': [4110], '96:': [4114], '136-142Crossref': [4115], '(102)': [4118], '38.Lasley': [4121], 'R.D.': [4122], 'Keith': [4123], 'B.J.': [4124], 'Kristo': [4125], 'Yoshimura': [4127], 'Mentzer': [4129], 'Delayed': [4131], 'adenosine': [4132], 'A1': [4133], 'preconditioning': [4135], 'myocardium': [4138], 'MAPK': [4140], 'iNOS': [4143], 'independent.Am.': [4144], 'Physiol.': [4146, 4149], 'Heart': [4147], 'Circ.': [4148], '289:': [4151], 'H785-H791Crossref': [4152], '(27)': [4155], 'inhibitors,': [4170], 'followed': [4171, 4232], 'euthanization': [4173], 'later.': [4178], 'μl)': [4183], 'previously.': [4191], 'SDS-PAGE': [4199], 'Western': [4201], 'blotting': [4202], 'loading': [4209, 4245], 'primary': [4214], 'antibody': [4215, 4230], 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