Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2056062196', 'doi': 'https://doi.org/10.1016/0005-2760(74)90057-5', 'title': 'The effect of tryptophan administration on fatty acid synthesis in the liver of the fasted normal rat', 'display_name': 'The effect of tryptophan administration on fatty acid synthesis in the liver of the fasted normal rat', 'publication_year': 1974, 'publication_date': '1974-09-01', 'ids': {'openalex': 'https://openalex.org/W2056062196', 'doi': 'https://doi.org/10.1016/0005-2760(74)90057-5', 'mag': '2056062196', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4416225'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0005-2760(74)90057-5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210194106', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism', 'issn_l': '0005-2760', 'issn': ['0005-2760', '1879-145X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110328760', 'display_name': 'Takehiko Sakurai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I137975476', 'display_name': 'Shinshu University', 'ror': 'https://ror.org/0244rem06', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I137975476']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takehiko Sakurai', 'raw_affiliation_strings': ['Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan', 'institution_ids': ['https://openalex.org/I137975476']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103498422', 'display_name': 'Shoko Miyazawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I137975476', 'display_name': 'Shinshu University', 'ror': 'https://ror.org/0244rem06', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I137975476']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shoko Miyazawa', 'raw_affiliation_strings': ['Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan', 'institution_ids': ['https://openalex.org/I137975476']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111436584', 'display_name': 'Yasuko Shindo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I137975476', 'display_name': 'Shinshu University', 'ror': 'https://ror.org/0244rem06', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I137975476']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yasuko Shindo', 'raw_affiliation_strings': ['Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan', 'institution_ids': ['https://openalex.org/I137975476']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5084472017', 'display_name': 'Takashi Hashimoto', 'orcid': 'https://orcid.org/0000-0002-8398-5479'}, 'institutions': [{'id': 'https://openalex.org/I137975476', 'display_name': 'Shinshu University', 'ror': 'https://ror.org/0244rem06', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I137975476']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takashi Hashimoto', 'raw_affiliation_strings': ['Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Faculty of Medicine, Shinshu University, Matsumoto, Japan', 'institution_ids': ['https://openalex.org/I137975476']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.169, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 17, 'citation_normalized_percentile': {'value': 0.791133, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '360', 'issue': '3', 'first_page': '275', 'last_page': '288'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12267', 'display_name': 'Diet and metabolism studies', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12267', 'display_name': 'Diet and metabolism studies', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12964', 'display_name': 'Diet, Metabolism, and Disease', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11027', 'display_name': 'Metabolism and Genetic Disorders', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2776706248', 'wikidata': 'https://www.wikidata.org/wiki/Q181003', 'display_name': 'Tryptophan', 'level': 3, 'score': 0.7351836}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5833223}, {'id': 'https://openalex.org/C2778772119', 'wikidata': 'https://www.wikidata.org/wiki/Q6058862', 'display_name': 'Fatty liver', 'level': 3, 'score': 0.5141671}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5009332}, {'id': 'https://openalex.org/C2780765947', 'wikidata': 'https://www.wikidata.org/wiki/Q12033531', 'display_name': 'Administration (probate law)', 'level': 2, 'score': 0.47494557}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.45641616}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.44544566}, {'id': 'https://openalex.org/C543025807', 'wikidata': 'https://www.wikidata.org/wiki/Q61476', 'display_name': 'Fatty acid', 'level': 2, 'score': 0.41986722}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.37470978}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2289601}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.1021831}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C17744445', 'wikidata': 'https://www.wikidata.org/wiki/Q36442', 'display_name': 'Political science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199539241', 'wikidata': 'https://www.wikidata.org/wiki/Q7748', 'display_name': 'Law', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005227', 'descriptor_name': 'Fatty Acids', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014364', 'descriptor_name': 'Tryptophan', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000085', 'descriptor_name': 'Acetates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000085', 'descriptor_name': 'Acetates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000244', 'descriptor_name': 'Adenosine Diphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000244', 'descriptor_name': 'Adenosine Diphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000249', 'descriptor_name': 'Adenosine Monophosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000249', 'descriptor_name': 'Adenosine Monophosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000409', 'descriptor_name': 'Alanine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000409', 'descriptor_name': 'Alanine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002250', 'descriptor_name': 'Carbon Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002784', 'descriptor_name': 'Cholesterol', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D002784', 'descriptor_name': 'Cholesterol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002855', 'descriptor_name': 'Chromatography, Thin Layer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002952', 'descriptor_name': 'Citric Acid Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002952', 'descriptor_name': 'Citric Acid Cycle', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005215', 'descriptor_name': 'Fasting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005227', 'descriptor_name': 'Fatty Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005230', 'descriptor_name': 'Fatty Acids, Nonesterified', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005230', 'descriptor_name': 'Fatty Acids, Nonesterified', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D005990', 'descriptor_name': 'Glycerol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005990', 'descriptor_name': 'Glycerol', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008055', 'descriptor_name': 'Lipids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008055', 'descriptor_name': 'Lipids', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010743', 'descriptor_name': 'Phospholipids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010743', 'descriptor_name': 'Phospholipids', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D011768', 'descriptor_name': 'Pyruvate Dehydrogenase Complex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011768', 'descriptor_name': 'Pyruvate Dehydrogenase Complex', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011804', 'descriptor_name': 'Quinolines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014280', 'descriptor_name': 'Triglycerides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014280', 'descriptor_name': 'Triglycerides', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D014316', 'descriptor_name': 'Tritium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014364', 'descriptor_name': 'Tryptophan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014867', 'descriptor_name': 'Water', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0005-2760(74)90057-5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210194106', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism', 'issn_l': '0005-2760', 'issn': ['0005-2760', '1879-145X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4416225', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'score': 0.82, 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1254243414', 'https://openalex.org/W1482173162', 'https://openalex.org/W1484792585', 'https://openalex.org/W1490093099', 'https://openalex.org/W1493348989', 'https://openalex.org/W1511849515', 'https://openalex.org/W1513897103', 'https://openalex.org/W152486275', 'https://openalex.org/W1546324685', 'https://openalex.org/W1554239817', 'https://openalex.org/W1561383634', 'https://openalex.org/W1580313770', 'https://openalex.org/W1586878603', 'https://openalex.org/W1595308056', 'https://openalex.org/W1595878159', 'https://openalex.org/W1605667197', 'https://openalex.org/W1676193473', 'https://openalex.org/W1695034058', 'https://openalex.org/W1801184284', 'https://openalex.org/W181688216', 'https://openalex.org/W188363953', 'https://openalex.org/W1966809029', 'https://openalex.org/W1978760370', 'https://openalex.org/W1982690950', 'https://openalex.org/W1995599692', 'https://openalex.org/W1995957659', 'https://openalex.org/W2027461488', 'https://openalex.org/W2030574571', 'https://openalex.org/W2045183285', 'https://openalex.org/W2049737902', 'https://openalex.org/W2056617009', 'https://openalex.org/W2064857927', 'https://openalex.org/W2074968465', 'https://openalex.org/W2081145387', 'https://openalex.org/W2168526937', 'https://openalex.org/W2280456359', 'https://openalex.org/W2942507508', 'https://openalex.org/W403031918', 'https://openalex.org/W62898540'], 'related_works': ['https://openalex.org/W656753012', 'https://openalex.org/W2564874675', 'https://openalex.org/W2423942488', 'https://openalex.org/W2392315405', 'https://openalex.org/W2119281094', 'https://openalex.org/W2092897512', 'https://openalex.org/W203553400', 'https://openalex.org/W1993111975', 'https://openalex.org/W1850217954', 'https://openalex.org/W1522685369'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2056062196', 'counts_by_year': [{'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-12-11T13:04:04.826659', 'created_date': '2016-06-24'}