Publication Information

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'Medical': [69, 86, 103, 120, 137, 154, 171, 188, 205, 222], 'College,': [70, 87, 104, 121, 138, 155, 172, 189, 206, 223], 'Saitama,': [71, 88, 105, 122, 139, 156, 173, 190, 207, 224], 'Japan': [72, 89, 106, 123, 140, 157, 174, 191, 208, 225], 'Search': [73, 90, 107, 124, 141, 158, 175, 192, 209, 226], 'for': [74, 91, 108, 125, 142, 159, 176, 193, 210, 227, 447, 454, 462, 476, 484, 684, 793, 838, 1029, 1192], 'more': [75, 92, 109, 126, 143, 160, 177, 194, 211, 228, 1834], 'papers': [76, 93, 110, 127, 144, 161, 178, 195, 212, 229], 'by': [77, 94, 111, 128, 145, 162, 179, 196, 213, 230, 362, 410, 427, 432, 443, 450, 459, 472, 480, 499, 1330, 1886], 'this': [78, 95, 112, 129, 146, 163, 180, 197, 214, 231], 'author': [79, 96, 113, 130, 147, 164, 181, 198, 215, 232], ',': [80, 97, 114, 131, 148, 165, 182, 199], 'MomiyamaYukihiko': [82], 'Momiyama': [83, 1236, 1269], 'OhmoriReiko': [99], 'Ohmori': [100, 1234, 1271], 'YonemuraAtsushi': [116], 'Yonemura': [117], 'AyaoriMakoto': [133], 'Ayaori': [134, 1210, 1563], 'OguraMasatsune': [150], 'Ogura': [151, 1571], 'SawadaShojiro': [167], 'Sawada': [168], 'KusuharaMasatoshi': [184], 'Kusuhara': [185, 1212, 1242, 1279], 'NakamuraHaruo': [201], 'OhsuzuFumitaka': [218], 'Originally': [233, 2094], 'published1': [234], 'Aug': [235], '2006https://doi.org/10.1161/01.ATV.0000229701.42828.73Arteriosclerosis,': [236], 'Biology.': [240], '2006;26:e129–e130To': [241], 'the': [242, 280, 304, 335, 609, 634, 652, 786, 816, 824, 918, 997, 1052, 1077, 1114, 1254, 1773, 1797, 1806], 'EditorHigh': [243], 'levels': [244, 265, 289, 347, 407, 424, 491, 496, 549, 559, 579, 604, 624, 795, 822, 875, 885, 1083, 1126, 1250, 1287, 1497, 1687, 1766, 1881], 'osteopontin': [246, 1249, 1289, 1328, 1496, 1638, 1686, 1768, 1880], '(OPN)': [247], 'mRNA': [248, 318, 328, 896, 907], 'proteins': [250, 1194], 'were': [251, 368, 372, 381, 393, 408, 425, 441, 470, 497, 529, 1069], 'reported': [252, 262, 286, 993], 'atherosclerotic': [254, 1102, 1171, 1197], 'plaques.1,2': [255], 'OPN-transgenic': [256], 'mice': [257, 1220], 'developed': [258], 'marked': [259], 'atherosclerosis.3': [260], 'We': [261, 284], 'plasma': [263, 288, 345, 711, 820, 873, 923, 935, 1118, 1124, 1286, 1495, 1685, 1879, 1934], 'OPN': [264, 291, 299, 317, 327, 346, 406, 413, 490, 548, 558, 623, 637, 655, 821, 895, 906, 924, 936, 953, 958, 984, 1000, 1011, 1082, 1098, 1125, 1133], 'be': [267, 848, 853, 962, 1014, 1062, 1136], 'high': [268, 287, 419], 'patients': [270, 293, 351, 367, 392, 511, 533, 1291, 1378, 1506, 1689], 'with': [271, 279, 294, 563, 640, 785, 823, 844, 989, 1003, 1094, 1253, 1292, 1374, 1379, 1500, 1507, 1541, 1682, 1690, 1730, 1882, 1933, 1997], 'coronary': [272, 1259, 1296, 1883, 1888, 1926], 'artery': [273, 1260, 1642, 1927], 'disease': [274, 1504], '(CAD)': [275], 'correlate': [278, 562, 988], 'severity': [281], 'CAD.4': [283], 'also': [285], 'restenosis.5': [295], 'These': [296], 'suggest': [297], 'that': [298, 641, 796, 1004], 'plays': [300], 'a': [301, 977, 1035, 1166, 1222, 1321], 'role': [302], 'development': [305], 'atherosclerosis.': [307], 'In': [308, 859, 871, 891], 'vitro,': [309, 892], 'Takemoto': [310, 1306, 1343], 'et': [311], 'al6': [312], 'demonstrated': [313, 929], 'statins': [314, 837, 868, 893, 921, 1020, 1028, 1763], 'reduce': [316, 934], 'cultured': [320, 898], 'aortic': [321, 899, 1332], 'smooth': [322, 900, 1333], 'muscle': [323, 901, 1334], 'cells': [324, 902], 'upregulated': [326, 905], 'aorta': [330, 909], 'diabetic': [332, 911, 1943], 'rats.We': [333], 'investigated': [334], 'effects': [336, 835, 857, 866, 1018, 1026, 1140, 1348], '20': [338], 'mg/d': [339, 342], 'versus': [340], '5': [341], 'atorvastatin': [343, 931, 943, 1080, 1121], '40': [349], 'hypercholesterolemic': [350, 1128, 1414], 'without': [352], 'any': [353, 1087], 'history': [354], 'cardiovascular': [356, 839, 1030], 'disease.': [357, 1261], 'Our': [358, 926, 1058], 'study': [359, 927, 1032, 1093], 'was': [360, 386, 401, 507, 588, 614, 649, 695, 707, 1033, 1043], 'approved': [361, 1054], 'institutional': [363], 'ethics': [364], 'committee.': [365], 'If': [366, 388], 'taking': [369], 'statins,': [370], 'these': [371], 'discontinued.': [373], 'After': [374, 524, 568, 759], '4-week': [375], 'washout': [376], 'period,': [377], 'fasting': [378, 710], 'blood': [379, 399, 527, 698, 727], 'samples': [380, 528, 1068], 'taken': [382, 530, 1070], 'after': [383, 403, 877, 887, 1294, 1640], 'informed': [384], 'consent': [385], 'obtained.': [387], 'LDL-cholesterol': [389, 417, 493, 564, 578, 586, 660, 946], '>150': [390], 'mg/dL,': [391], 'randomized': [394], 'either': [396], 'dose.': [397], 'Repeat': [398], 'sampling': [400], 'scheduled': [402], '6-month': [404, 469, 888, 930], 'treatment.': [405], 'measured': [409, 426], 'ELISA': [411], '(Human': [412], 'assay': [414], 'kit,': [415], 'IBL).': [416], 'sensitivity': [420], 'C-reactive': [421, 1372], 'protein': [422, 1373], '(hsCRP)': [423], 'direct': [428], 'enzymatic': [429], 'method': [430], 'BNII': [433], 'nephelometer': [434], '(Dade': [435], 'Behring).': [436], 'Differences': [437, 465], 'between': [438, 466, 487, 553, 651, 966], '2': [439, 554, 617, 967, 1509, 1942], 'groups': [440, 555], 'evaluated': [442, 471, 498, 1885], 'unpaired': [444], 't': [445, 474], 'test': [446, 453, 461, 475, 483], 'continuous': [448], 'variables,': [449], 'Mann–Whitney': [451], 'U': [452], 'nonparametric': [455], 'variables': [456, 478], '(hsCRP),': [457], 'χ2': [460], 'categorical': [463], 'variables.': [464], 'baseline': [467, 1072], 'paired': [473], 'parametric': [477], 'Wilcoxon': [481], 'rank': [482], 'hsCRP.': [485], 'Correlations': [486], 'changes': [488], 'or': [494, 565, 656, 678, 703, 716], 'other': [495, 1065], 'Pearson': [500], 'correlation': [501, 648], 'coefficient.': [502], 'A': [503, 1324, 1352, 1803], 'probability': [504], 'value': [505, 783], '<0.05': [506], 'considered': [508], 'significant.Of': [509], '50': [510], 'randomized,': [512], '6': [513, 525, 569, 760, 771, 777], 'withdrew': [514], 'their': [516], 'own': [517], 'accord,': [518], '4': [520], 'had': [521], 'adverse': [522], 'events.': [523], 'months,': [526], '18': [532], '20-mg': [535, 573, 591, 598, 620, 940, 950, 1041, 1120], 'dose': [536, 541, 595, 621, 629, 951, 1042, 1055], '22': [538], '5-mg': [540, 575, 594, 600, 628, 942], 'group.': [542, 596], 'At': [543], 'baseline,': [544], 'risk': [545], 'factors': [546], 'did': [550, 560, 630, 969, 986], 'not': [551, 561, 631, 970, 987, 1061, 1112], 'differ': [552], '(Table': [556, 571], '1).': [557], 'hsCRP': [566, 603, 612, 643, 657, 685, 794, 828, 874, 948, 1006], 'levels.': [567, 925, 937, 954], 'months': [570], '2),': [572], 'doses': [576, 601, 968], 'reduced': [577, 602, 622, 894, 945, 952, 1123], '(−47%': [580], '−35%).': [582], 'The': [583, 597, 619, 955, 981, 1008, 1130, 1722, 2052], 'degree': [584, 610, 635, 956, 982, 998], 'reduction': [587, 613, 638, 644, 658, 818, 826, 959, 985, 1001, 1009, 1131, 1370], 'greater': [589, 849], 'than': [592, 850, 1836], '(−44%': [605], '−44%),': [607], 'but': [608, 964], 'similar': [615], 'groups.': [618], '(−19%,': [625], 'P<0.05),': [626], 'whereas': [627], '(−7%).': [632], 'Notably,': [633], 'correlated': [639, 1002], '(r=0.51)': [645], '(Figure).': [646], 'No': [647], 'found': [650], 'degrees': [653], 'reduction.': [661, 1007], 'TABLE': [662], '1.': [663], 'Baseline': [664, 774, 780], 'Demographic': [665], 'Laboratory': [667], 'Characteristics20-mg': [668], 'Dose': [669, 671, 765, 767], '(n=18)5-mg': [670, 766], '(n=22)P': [672], 'ValueData': [673], 'are': [674, 688, 788, 797, 1251, 1498], 'presented': [675, 689, 789, 798], 'as': [676, 690, 697, 709, 790, 799, 992, 1045, 1104, 1106], 'mean±SD': [677], 'numbers': [679], '(%)': [680], 'patients,': [682, 1648, 1944], 'except': [683, 792], 'levels,': [686, 949], 'which': [687], 'median': [691, 800], '(interquartile': [692, 801], 'range).': [693], 'Hypertension': [694, 1649], 'defined': [696, 708], 'pressures': [699], '≥140/90': [700], 'mm': [701, 729], 'Hg': [702], 'medication.': [705], 'Diabetes': [706, 1945], 'glucose': [712], 'level': [713], '≥126': [714], 'mg/dL': [715], 'treatment.Age,': [718], 'years61±864±6NSMales7': [719], '(39%)6': [720], '(27%)NSBody': [721], 'mass': [722], 'index,': [723], 'kg/m225±325±2NSHypertension6': [724], '(33%)8': [725], '(36%)NSSystolic': [726], 'pressure,': [728], 'Hg126±13125±11NSCurrent': [730], 'smoker1': [731], '(6%)2': [732], '(9%)NSDiabetes': [733], 'mellitus4': [734], '(22%)3': [735], '(14%)NSFasting': [736], 'glucose,': [737, 806], 'mg/dL113±3399±11NSPrior': [738], 'statin': [739, 845], 'use6': [740], '(33%)9': [741], '(41%)NSLDL-cholesterol,': [742], 'mg/dL196±37201±38NSTriglycerides,': [743], 'mg/dL169±58147±55NSHDL-cholesterol,': [744], 'mg/dL60±1664±14NShsCRP,': [745], 'mg/L0.71': [746], '(0.68–0.91)0.65': [747], '(0.35–2.03)NSCreatinine,': [748], 'mg/dL0.69±0.140.74±0.10NSOsteopontin,': [749], 'ng/mL751±272761±259NSTABLE': [750], '2.': [751], 'Serum': [752, 881, 1458, 1532], 'Lipids,': [753], 'hsCRP,': [755, 808], 'Months': [761], 'Treatment20-mg': [764], '(n=22)20-mg': [768], 'vs': [769], '5-mgAfter': [770], 'monthsChange': [772, 778], 'From': [773, 779], '(%)P': [775, 781], 'Value*After': [776], 'Value**P': [782], 'compared': [784], 'baseline.Data': [787], 'mean±SD,': [791], 'range).LDL-cholesterol,': [802], 'mg/dL104±28−47%<0.001130±35−35%<0.001<0.001Triglycerides,': [803], 'mg/dL113±32−33%<0.001131±56−11%NS<0.05HDL-cholesterol,': [804], 'mg/dL63±17+4%NS64±13+1%NSNSFasting': [805], 'mg/dL118±37+5%NS98±80%NSNSMedian': [807], 'mg/L0.40': [809], '(0.30–0.49)−44%<0.0010.36': [810], '(0.22–0.77)−44%<0.001NSOsteopontin,': [811], 'ng/mL611±266−19%<0.05711±215−7%NSNSDownload': [812], 'figureDownload': [813], 'PowerPointCorrelation': [814], 'percent': [817, 825], 'levels.Several': [829], 'large': [830], 'clinical': [831, 1088], 'trials': [832], 'showed': [833, 862], 'beneficial': [834, 1025], 'diseases.7': [840], 'Clinical': [841, 1469, 1551, 1608, 1733, 1948, 2055], 'benefits': [842], 'observed': [843], 'appeared': [846, 960], 'what': [851], 'might': [852], 'expected': [854], 'from': [855, 1595, 1772], 'lipid-altering': [856], 'alone.': [858], 'vitro': [860, 1598], 'studies': [861], 'some': [863], 'non-lipid': [864], 'pleiotropic': [865, 1017, 1139], 'atherosclerosis.7': [870], 'vivo,': [872], 'decreased': [876, 886], '8-week': [878], 'cerivastatin': [879, 1375], 'treatment.8': [880], 'matrix': [882, 1419], 'metalloproteinase': [883], '(MMP)-9': [884], 'pravastatin': [889, 1411], 'treatment.9': [890], 'abnormally': [904], 'rats.6': [912], 'However,': [913, 1109], 'no': [914], 'report': [915], 'has': [916], 'shown': [917], 'effect': [919, 1078], 'first': [928], 'treatment': [932, 1122, 1839], 'Although': [938], 'both': [939], 'markedly': [944], 'dose-dependent,': [963], 'difference': [965], 'reach': [971], 'statistical': [972], 'significance,': [973], 'probably': [974], 'because': [975, 1049], 'small': [978, 1036], 'sample': [979], 'size.': [980], 'LDL-C': [990], 'reduction,': [991], 'hsCRP.8': [995], 'Interestingly,': [996], 'production': [1012, 1134], 'may': [1013, 1022, 1060, 1135], 'one': [1015, 1137], 'contribute': [1023], 'diseases.Our': [1031], 'number': [1037], 'Japanese': [1039], 'patients.': [1040, 1129], 'used': [1044], 'high-dose': [1046], 'atorvastatin,': [1048], 'it': [1050], 'is': [1051, 1096, 1099, 1156, 1165, 1833], 'maximal': [1053], 'Japan.': [1057], 'results': [1059], 'applicable': [1063], 'ethnicities.': [1066], 'Blood': [1067], 'at': [1071], '6-month.': [1074], 'To': [1075], 'validate': [1076], 'provide': [1086], 'end': [1089], 'point': [1090], 'correlations,': [1091], 'further': [1092], 'follow-up': [1095], 'needed.': [1097], 'synthesized': [1100], 'plaques': [1103], 'well': [1105], 'mineralized': [1107], 'tissues.': [1108], 'we': [1110], 'could': [1111], 'determine': [1113], 'main': [1115], 'source': [1116], 'OPN.Thus,': [1119], 'statins.DisclosuresNone.1': [1142], 'Giachelli': [1143], 'CM,': [1144, 1181], 'Bae': [1145], 'N,': [1146, 1215, 1274, 1366, 1521, 1818, 1820, 1868, 1958, 1966], 'Almeida': [1147], 'M,': [1148, 1211, 1213, 1243, 1280, 1307, 1309, 1344, 1396, 1444, 1477, 1483, 1564, 1572, 1578, 1617, 1623, 1659, 1669, 1705, 1715, 1856, 1905, 2031], 'Denhardt': [1149], 'DT,': [1150], 'Alpers': [1151], 'CE,': [1152], 'Schwartz': [1153], 'SM.': [1154], 'elevated': [1157, 1765], 'during': [1158], 'neointima': [1159], 'formation': [1160], 'rat': [1162, 1331], 'arteries': [1163], 'novel': [1167], 'component': [1168], 'human': [1170, 1196], 'plaques.': [1172, 1198], 'J': [1173, 1199, 1337, 1422, 1631, 1676, 1720, 1922, 2035], 'Clin': [1174, 1200], 'Invest.': [1175, 1201], '1993;': [1176], '92:': [1177], '1686–1696.CrossrefMedlineGoogle': [1178], 'Scholar2': [1179], 'Shanahan': [1180], 'Cary': [1182], 'NRB,': [1183], 'Metcalfe': [1184], 'JC,': [1185], 'Weissberg': [1186], 'PL.': [1187], 'High': [1188, 1285], 'expression': [1189, 1329], 'genes': [1191], 'calcification-regulating': [1193], '1994;': [1202], '93:': [1203], '2393–2402.CrossrefMedlineGoogle': [1204], 'Scholar3': [1205], 'Isoda': [1206], 'K,': [1207, 1278, 1311, 1446, 1566, 1671, 1978], 'Kamezawa': [1208], 'Y,': [1209, 1237, 1270, 1317, 1574, 1621, 1913, 1915], 'Tada': [1214], 'F.': [1217, 1247, 1284], 'transgenic': [1219], 'fed': [1221], 'high-cholesterol': [1223], 'diet': [1224], 'develop': [1225], 'early': [1226], 'fatty-streak': [1227], 'lesions.': [1228], 'Circulation.': [1229, 1382], '2003;': [1230, 1263], '107:': [1231], '679–681.LinkGoogle': [1232], 'Scholar4': [1233], 'R,': [1235, 1241, 1268, 1272, 1390, 1402], 'Taniguchi': [1238, 1275], 'H,': [1239, 1245, 1276, 1282, 1562, 1576, 1625, 1747, 1911], 'Takahashi': [1240], 'associated': [1252, 1499], 'presence': [1255], 'extent': [1257], 'Atherosclerosis.': [1262], '170:': [1264], '333–337.CrossrefMedlineGoogle': [1265], 'Scholar5': [1266], 'Kato': [1267], 'Arakawa': [1277], 'restenosis': [1293], 'percutaneous': [1295], 'intervention.': [1297], 'Arterioscler': [1298, 1355], 'Thromb': [1299, 1356], 'Vasc': [1300, 1357], 'Biol.': [1301, 1358], '2006;': [1302], '26:': [1303], 'e1–e2.LinkGoogle': [1304], 'Scholar6': [1305], 'Kitahara': [1308], 'Yokote': [1310], 'Asaumi': [1312], 'S,': [1313, 1481, 1525, 1568, 1749, 1870, 1917, 1976], 'Take': [1314], 'A,': [1315, 1388, 1785, 1822, 1824, 1858, 1962, 1964, 1972, 2021], 'Saito': [1316], 'Mori': [1318], 'S.': [1319], 'NK-104,': [1320], '3-hydroxy-4-methilglutaryl': [1322], 'coenzyme': [1323, 1351], 'reductase': [1325, 1353], 'inhibitor,': [1326], 'reduces': [1327], 'cells.': [1335], 'Br': [1336], 'Pharmacol.': [1338], '2001;': [1339, 1359, 1383, 1424], '133:': [1340], '83–88.CrossrefMedlineGoogle': [1341], 'Scholar7': [1342], 'Liao': [1345], 'JK.': [1346], 'Pleiotropic': [1347], '3-hydroxy-3-methylglutaryl': [1350], 'inhibitors.': [1354], '21:': [1360], '1712–1719.CrossrefMedlineGoogle': [1361], 'Scholar8': [1362], 'Ridker': [1363], 'PM,': [1364], 'Rifai': [1365], 'Lowenthal': [1367], 'SP.': [1368], 'Rapid': [1369], 'among': [1376], '785': [1377], 'primary': [1380], 'hyprecholesterolemia.': [1381], '103:': [1384], '1191–1193.CrossrefMedlineGoogle': [1385], 'Scholar9': [1386], 'Kalela': [1387], 'Laaksonen': [1389], 'Lehtimaki': [1391], 'T,': [1392, 1398, 1580, 1584, 1619, 1627, 1629, 1661, 1667, 1707, 1713, 1862, 1960], 'Koivu': [1393], 'TA,': [1394], 'Hoyhtya': [1395], 'Janatuinen': [1397], 'Pollanen': [1399], 'P,': [1400, 1404, 1974], 'Vesalainen': [1401], 'Saikku': [1403], 'Knuuit': [1405], 'J,': [1406, 1436, 1438, 1448, 1450, 1479, 1663, 1709, 1745, 1751, 1909, 2015, 2033], 'Nikkari': [1407], 'ST.': [1408], 'Effect': [1409], 'mildly': [1413], 'young': [1415], 'men': [1416], 'serum': [1418], 'metalloproteinases.': [1420], 'Am': [1421], 'Cardiol.': [1423], '88:': [1425], '173–175.CrossrefMedlineGoogle': [1426], 'Scholar': [1427], 'Previous': [1428], 'Back': [1429], 'top': [1431], 'Next': [1432], 'FiguresReferencesRelatedDetailsCited': [1433], 'By': [1434], 'Bartosińska': [1435], 'Przepiórka-Kosińska': [1437], 'Sarecka-Hujar': [1439], 'B,': [1440, 2019], 'Raczkiewicz': [1441], 'D,': [1442, 1487, 1665, 1711, 1866], 'Kowal': [1443], 'Chyl-Surdacka': [1445], 'Bartosiński': [1447], 'Kosiński': [1449], 'Krasowska': [1451], 'D': [1452, 1756], 'Chodorowska': [1454], 'G': [1455, 1489, 2038], '(2021)': [1456], 'Concentration': [1459], 'Metabolic': [1461], 'Syndrome': [1462], 'Male': [1464], 'Psoriatic': [1465], 'Patients,': [1466], 'Journal': [1467, 1606, 1693, 1844, 1891, 2001, 2053], 'Medicine,': [1470], '10.3390/jcm10040755,': [1471], '10:4,': [1472], '(755)': [1473], 'Wang': [1474], 'C,': [1475, 2025, 2029], 'He': [1476], 'Peng': [1478], 'Li': [1480], 'Long': [1482], 'Chen': [1484], 'W,': [1485], 'Liu': [1486], 'Yang': [1488], 'Zhang': [1491], 'L': [1492], '(2020)': [1493], 'Increased': [1494, 2049], 'nonalcoholic': [1501], 'fatty': [1502], 'liver': [1503], 'type': [1508, 1941], 'diabetes': [1510], 'mellitus,': [1511], 'Cytokine,': [1512], '10.1016/j.cyto.2019.154837,': [1513], '125,': [1514], '(154837),': [1515], 'Online': [1516, 1557, 1654, 1700, 1740, 1780, 1813, 1851, 1900, 1953, 2010, 2062, 2080], 'publication': [1517, 1558, 1655, 1701, 1741, 1781, 1814, 1852, 1901, 1954, 2011, 2063, 2081], 'date:': [1518, 1559, 1656, 1702, 1742, 1782, 1815, 1853, 1902, 1955, 2012, 2064, 2082], '1-Jan-2020.': [1519], 'Kadoglou': [1520, 1817, 1957], 'Kottas': [1522], 'G,': [1523, 1582, 1787, 1968], 'Lampropoulos': [1524], 'Vitta': [1526, 1969], 'I': [1527], 'Liapis': [1529, 1828, 1982], 'C': [1530, 1829, 1983], '(2013)': [1531], 'Fetuin-A,': [1535], 'Osteoprotegerin': [1536], 'Coronary': [1542], 'Artery': [1543], 'Disease:': [1544], 'Effects': [1545], 'Statin': [1547], '(HMGCoA-Reductase': [1548], 'Inhibitor)': [1549], 'Therapy,': [1550], 'Drug': [1552], 'Investigation,': [1553], '10.1007/s40261-013-0157-y,': [1554], '34:3,': [1555], '(165-171),': [1556], '1-Mar-2014.': 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