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[418], 'et': [421, 1018, 1422, 1746], 'al.': [422, 1747], '(1979).': [423], 'The': [424, 489, 1385], 'matrix': [425, 1720], 'protein': [426], 'determines': [428], 'sensitivity': [431, 2091], '42,': [438], '3021–3024.': [439], '10.1099/0022-1317-42-1-189': [440], 'Web': [441, 591], '9': [445], 'Smith,': [449], 'H.,': [451, 822, 1213, 1524, 1568, 1830], 'Hall,': [452, 1197, 1701], 'Betts,': [455, 776, 2007, 2045], '(1988).': [461, 789, 1794], 'Genetic': [462, 625], 'basis': [463], 'resistance': [465, 533, 649, 873], 'emerging': [468], 'during': [469, 753, 846, 1181, 1355, 1492, 1544, 1584], 'treatment': [470, 758, 984, 1236, 1270, 1392, 2061, 2116], 'infection.': [474, 1102], '62,': [477], '1508–1512.': [478], '10.1128/JVI.62.5.1508-1512.1988': [479], '10': [484, 545, 657], 'mechanism': [490], 'action': [492, 537], 'against': [497], 'in,': [500, 571, 954, 1005, 1681], 'Concepts': [501], 'Viral': [503, 1009], 'Pathogenesis,': [504], 'Volume': [505], 'III,': [506], 'ed.': [507, 581, 630, 961, 1013, 1683], 'Notkins': [511], 'Oldstone,': [516], 'pp.': [517, 585, 634, 966, 1020, 1692], '561–567.': [518], 'Springer-Verlag,': [519, 636], 'Berlin.': [520, 637], 'Google': [521, 549, 639, 661, 972, 1026, 1599, 1698, 2004, 2038], '11': [523], 'Drug': [532, 980], 'mechanisms': [535], 'on': [538, 1456, 1878, 1930, 1966], 'Resp.': [543, 655], '(Suppl': [546, 658], '12A),': [547, 659], 'S52–S61.': [548], '12': [551], 'Grambas,': [555, 1644], 'Bennett,': [558], '(1991).': [561, 1348, 1536, 1650, 1962, 1986, 2082], 'rimantadine.': [570, 615, 1238, 1359, 1396, 1427], 'Advances': [572], 'Molecular': [574], 'Biology': [575], 'Targeted': [577], 'Treatment': [578], 'AIDS,': [580], 'Kumar,': [584], '345–353.': [586], 'Plenum,': [587], 'New': [588, 1024, 1696], 'York.': [589, 1025, 1697], '10.1007/978-1-4684-5928-9_32': [590], '13': [595], '(1992).': [603, 1618], 'Emergence': [604, 746, 1307, 1537, 1575], 'transmission': [606, 1310, 1540], 'In,': [616], 'Current': [617, 914], 'Topics': [618], 'Microbiology': [620], 'Immunology,': [622], 'Vol.': [623], '176:': [624], 'Diversity': [626], 'RNA': [628], 'Viruses,': [629], 'Holland,': [633], '119–130.': [635], '10.1007/978-3-642-77011-1_8': [638], '14': [641], 'Significance': [646], 'S62–S67.': [660], '15': [663], 'Webster,': [664, 710, 742, 1676], 'Kawaoka,': [667], 'Y.,': [668], 'Bean,': [669, 703], 'Beard,': [672, 736], 'Brugh,': [676, 739], '(1985).': [678, 913], 'Chemotherapy': [679], 'vaccination:': [681], 'possible': [683, 1539], 'strategy': [684], 'control': [687, 1847, 1989], 'highly': [689], 'virulent': [690], '55,': [695], '173–176.': [696], '10.1128/JVI.55.1.173-176.1985': [697], '16': [702], 'Threlkeld,': [706], 'Biologic': [714], 'potential': [715], 'amantadine-resistant': [717, 748, 1542, 1577], 'avian': [723, 750, 1753], 'model.': [724], '1050–1056.': [729], '10.1093/infdis/159.6.1050': [730], '17': [735], 'W.,': [738, 827, 1251, 1439, 1474, 1516], '(1987).': [745, 942, 1122, 1230, 1261, 2022], 'H5N2': [749], 'simulated': [755], 'layer': [756], 'flock': [757], 'program.': [759], 'Avian': [760], '31,': [762, 1139], '533–537.': [763], '10.2307/1590736': [764], '17a': [769], 'Sears,': [770, 1115, 1150], 'Clements,': [773, 1119, 1153, 1168], 'L.,': [775, 1155, 1158, 1204, 1222, 1609, 1742, 1833, 1956], 'Maassab,': [779], 'V.,': [781], 'Murphy,': [782, 1672, 1737], 'Synder,': [786], 'Comparison': [790], 'live': [792], 'attenuated': [793, 1760], 'H1N1': [794], 'H3N2': [796], 'cold-adapted': [797], 'avian-human': [799], 'reassortant': [802], 'inactivated': [805], 'vaccine': [807], 'adults.': [809], '158,': [813], '1209–1219.': [814], '10.1093/infdis/158.6.1209': [815], '18': [820, 886, 2124], 'Heider,': [821], 'Adamczyk,': [823], 'Presber,': [825], 'Schroeder,': [828], 'C.,': [829, 1037, 1040, 1076, 1637, 1916], 'Feldblum,': [830], 'Indulen,': [833], '(1981).': [836, 1708, 2059], 'Occurrence': [837], 'amantadine-': [839], 'rimantadine-resistant': [841, 1312, 1653], '1980': [848], 'epidemic.': [849, 1185], 'Acta': [850], '25,': [852], '395–400.': [853], '19': [858], 'Pemberton,': [859], 'M.,': [861, 1164, 1207], 'Jennings,': [862], 'R.,': [863, 903, 1073, 1081, 1160, 1201, 1526, 1739, 1824, 1827], '(1986).': [871, 1844, 2110], 'Amantadine': [872], 'clinical': [875], '(H3N2)': [878, 1657], '(H1N1)': [880], 'isolates.': [882], '(Suppl.': [887, 2125], 'B),': [888, 2126], '135–140.': [889], 'PubMedWeb': [890, 994], '20': [894], 'Bektimirov,': [895], 'T.': [896, 1781, 1823], 'A.,': [897, 1216, 1376, 1776, 1818], 'Jr.,': [901, 1786], 'Dolin,': [902, 1072, 1200, 2020], 'Galasso,': [904], 'Krylov,': [907], 'V.': [908], 'status': [915], 'anti-influenza-A': [921], 'agents:': [922], 'Memorandum': [923], 'from': [924, 1752], 'WHO': [926], 'meeting.': [927], 'Bull.': [928, 1502], 'WHO,': [929, 1503], '63,': [930], '51–56.': [931], 'PubMedGoogle': [932], '21': [934], 'Tominack,': [935], 'Rimantadine': [943, 1795], 'hydrochloride': [944, 947, 1056, 1455, 1489, 1929], 'use': [948, 1357, 2088], 'infections.': [953, 1973, 2120], 'Infectious': [955], 'Disease': [956], 'Clinics': [957], 'North': [959], 'America,': [960], 'Moellering,': [965], '459–478.': [967], 'Saunders,': [970], 'Philadelphia.': [971], '22': [974], '(1990).': [979, 1002, 1171, 1415, 1574, 1679, 1874], 'therapy.': [981], 'Prophylaxis': [982], 'influenza.': [986], 'Engl.': [988, 1104, 1319], 'Med.,': [990, 1106, 1321, 1429, 1628], '322,': [991], '443–450.': [992], '10.1056/NEJM199002153220706': [993], '22a': [998], 'Respiratory': [1003], 'diseases.': [1004], 'Antiviral': [1006, 1062, 1397, 2023, 2098], 'Diseases': [1010], 'Man,': [1012], 'Galasso': [1017], 'al.,': [1019], '327–372.': [1021], 'Raven': [1022, 1694], 'Press,': [1023, 1695], '23': [1028], 'Reuman,': [1029, 1905], 'Bernstein,': [1032, 1908], 'D.': [1033, 1117, 1157, 1206, 1382, 1570, 1611, 1689, 1741, 1909, 2017], 'I.,': [1034, 1373, 1910], 'Keefer,': [1035], 'Young,': [1038, 1914], 'E.': [1039, 1229, 1375, 1379, 1512, 1744, 1915], 'Sherwood,': [1041, 1917], 'Schiff,': [1045, 1921], 'Efficacy': [1049], 'safety': [1051], 'low': [1053], 'dosage': [1054], 'prophylaxis': [1058, 1098, 1796], 'Res.,': [1063, 1398], '11,': [1064, 1399], '27–40.': [1065], '10.1016/0166-3542(89)90018-1': [1066], '24': [1071], 'Reichman,': [1074], 'Madore,': [1077, 1211], 'P.,': [1079, 1521, 1821, 1913, 2044], 'Maynard,': [1080], 'Linton,': [1082], 'Webber-Jones,': [1086], '(1982).': [1088, 1748], 'controlled': [1090], 'trial': [1091], '307,': [1107], '580–584.': [1108], '10.1056/NEJM198209023071002': [1109], '25': [1114], 'Protective': [1123, 1451], 'efficacy': [1124, 1175], 'low-dose': [1126, 1177], 'adults': [1129, 1180], 'challenged': [1130], 'wild-type': [1132], '1470–1473.': [1140], '10.1128/AAC.31.10.1470': [1141], '26': [1146], 'Brady,': [1147], 'Pacini,': [1156], 'Samorodin,': [1159], 'DePamphilis,': [1161], 'Oakes,': [1163, 1300], 'Soo,': [1165, 1304], 'Safety': [1172], 'prophylactic': [1174], '34,': [1189, 1977], '1633–1636.': [1190], '10.1128/AAC.34.9.1633': [1191], '27': [1196], 'Gala,': [1202], 'Markovitz,': [1205], 'Zhang,': [1208], 'Y.': [1209], 'Q.,': [1210], 'Disney,': [1214], 'Talpey,': [1217], 'Green,': [1220], 'Francis,': [1223], 'Pichichero,': [1227], 'Children': [1231], 'infection:': [1235], 'Pediatrics,': [1239], '80,': [1240], '275–282.': [1241], '10.1542/peds.80.2.275': [1242], '28': [1247], 'Thompson,': [1248], 'Fleet,': [1250], 'Lawrence,': [1252], 'E.,': [1253, 1255, 1513, 1566, 1865], 'Pierce,': [1254], 'Morris,': [1256], 'Wright,': [1259], 'comparison': [1263], 'acetaminophen': [1265], 'infection': [1274], 'children.': [1276], 'Med.': [1278, 1941, 1975, 2070], '21,': [1280], '10.1002/jmv.1890210308': [1282], '29': [1287], 'Clover,': [1294, 1339, 1777, 1951], 'apparent': [1309], 'families.': [1317], '321,': [1322], '1696–1702.': [1323], '10.1056/NEJM198912213212502': [1324], '30': [1329], 'Sperber,': [1333], 'Pyke,': [1346], 'Recovery': [1349], 'drugresistant': [1351], 'therapeutic': [1356], '35,': [1363], '1741–1747.': [1364], '10.1128/AAC.35.9.1741': [1365], '31': [1370], 'Kubar,': [1371], 'O.': [1372], 'Brjantseva,': [1374], 'Nikitina,': [1377], 'Zlydnikov,': [1381], 'drug-resistance': [1389], '313–316.': [1400], '10.1016/0166-3542(89)90041-7': [1401], '32': [1406], 'Bricaire,': [1407], 'Hannoun,': [1409], 'Boissel,': [1412], 'Prevention': [1416, 1987], 'de': [1417, 1426], 'la': [1418], 'grippe': [1419], 'Efficacite': [1421], 'tolerance': [1423], 'du': [1424], 'chlorhydrate': [1425], 'Presse': [1428], '19,': [1430], '69–72.': [1431], '33': [1436], 'Galbraith,': [1437, 1472], 'Schild,': [1443, 1478], 'Watson,': [1447, 1482], '(1969).': [1450, 1485], 'effect': [1452, 1926], '1-adamantanamine': [1454, 1488], 'family': [1461, 1500], 'environment.': [1462, 1501], 'Lancet,': [1463], '1026–1028.': [1465], '10.1016/S0140-6736(69)90639-4': [1466], '34': [1471], 'Study': [1486], 'used': [1490], 'prophylactically': [1491], 'Hong': [1494], 'Kong': [1495], 'epidemic': [1497], '41,': [1504], '677–682.': [1505], '35': [1510], 'Mast,': [1511], 'Harmon,': [1514], 'Gravenstein,': [1517], 'Wu,': [1519], 'Arden,': [1522], 'Circo,': [1525], 'Tyszka,': [1527], 'Kendal,': [1529, 2079], 'Davis,': [1533, 1960], 'nursing': [1545, 1582, 1624], 'home': [1546], 'outbreaks': [1547], '(H3N2).': [1551], 'Am.': [1552, 2069], 'Epidemiol.,': [1554], '134,': [1555], '988–997.': [1556], '10.1093/oxfordjournals.aje.a116184': [1557], '36': [1562], 'Roumillat,': [1563], 'Rocha,': [1565], 'Regnery,': [1567], 'Wells,': [1569], 'Cox,': [1572], 'N.,': [1573, 1785], 'homes': [1583], '1989–90': [1586], 'season': [1588], '(Abstr': [1589], 'P34–42).': [1590], '8th': [1591], 'International': [1592], 'Congress': [1593], 'Virology,': [1595, 1682], 'Berlin,': [1596], '321.': [1598], '36a': [1601], 'Degelau,': [1602], 'Somani,': [1604], 'K.,': [1606, 1867], 'Cooper,': [1607], 'Guay,': [1610], 'Crossley,': [1615], 'Amantadine-resistant': [1619], 'facility.': [1625], 'Arch.': [1626], 'Intern.': [1627], '152,': [1629], '390–392.': [1630], '37': [1635], 'Sweet,': [1636], 'Jakeman,': [1641], 'Virulence': [1651], 'human': [1654, 1755, 2094], 'ferrets.': [1660], '164,': [1664], '969–972.': [1665], '10.1093/infdis/164.5.969': [1666], '38': [1671], 'Orthomyxo-viruses.': [1680], 'Fields': [1687], 'Knipe,': [1691], '1091–1152.': [1693], '39': [1700], 'Air,': [1705], 'Variation': [1709], 'nucleotide': [1711], 'sequences': [1712], 'N-terminal': [1716], 'regions': [1717], 'nonstructural': [1722], 'proteins': [1723], '38,': [1730], '1–7.': [1731], '40': [1736, 2001], 'Sly,': [1740], 'Tierney,': [1743], 'Reassortant': [1749], 'derived': [1751], 'immunogenic': [1762], 'monkeys.': [1764], 'Science,': [1765], '218,': [1766], '1330–1332.': [1767], '10.1126/science.6183749': [1768], '41': [1773], 'Crawford,': [1774], 'Abell,': [1780], 'Ramsey,': [1783], 'Glezen,': [1787, 1819], 'children:': [1798], 'follow-up': [1800], 'study.': [1801], 'Pediatr.': [1802], '7,': [1805], '379–383.': [1806], '10.1097/00006454-198806000-00002': [1807], '42': [1812], 'Kasel,': [1816], 'Cate,': [1822], 'Six,': [1825], 'Taber,': [1828], 'Frank,': [1831], 'Greenberg,': [1834], 'Zahradnik,': [1837], 'Keitel,': [1841], 'Influenza:': [1845], 'Its': [1846], 'persons': [1849], 'populations.': [1851], '153,': [1855], '431–440.': [1856], '10.1093/infdis/153.3.431': [1857], '43': [1862], 'Herrmann,': [1863], 'West,': [1866], 'Bruns,': [1868], 'Ennis,': [1871], 'Effect': [1875, 1963], 'cytotoxic': [1879], 'T': [1880], 'lymphocyte': [1881], 'responses': [1882], 'immunity': [1884], 'reinfection': [1886], 'mice': [1888], 'infected': [1889], '161,': [1897], '180–184.': [1898], '10.1093/infdis/161.2.180': [1899], '44': [1904], 'Keely,': [1911], 'Differential': [1925], 'systemic': [1932], 'local': [1934], 'immune': [1935, 1968], 'response': [1936, 1969], '27,': [1943], '137–141.': [1944], '10.1002/jmv.1890270213': [1945], '45': [1950], 'Waner,': [1954], 'Becker,': [1957], '68–73.': [1978], '10.1002/jmv.1890340112': [1979], '46': [1984], 'ACIP': [1985], 'influenza:': [1991], 'recommendations': [1992], 'Immunization': [1995], 'Practices': [1996], 'Advisory': [1997], 'Committee': [1998], '(ACIP).': [1999], 'MMWR,': [2000], '(no.': [2002], 'RR-6).': [2003], '47': [2006], 'Treanor,': [2010], 'Graman,': [2013], 'Bentley,': [2016], 'agents': [2024, 2114], 'prevent': [2026], 'or': [2027], 'treat': [2028], 'elderly.': [2032], 'Respir.': [2034], '8,': [2036], 'S56–S59.': [2037], '48': [2040], 'Van': [2041], 'Voris,': [2042], 'Christmas,': [2051], 'Successful': [2060], 'naturally': [2063], 'occurring': [2064], 'A/USSR/77': [2066], 'H1N1.': [2067], 'Assoc.,': [2071], '245,': [2072], '1128–1131.': [2073], '49': [2078], 'Short': [2083], 'communication.': [2084], 'Reference': [2085], 'Chem.': [2099], '115–118.': [2102], '10.1177/095632029100200207': [2103], 'CASGoogle': [2104], '50': [2106], 'Combinations': [2111], 'antiviral': [2113], '177–183.': [2127], 'Citing': [2132], 'Literature': [2133], 'Volume2,': [2134], 'Issue2June': [2135], '1992Pages': [2136], 'ReferencesRelatedInformation': [2138]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2055521109', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-09T08:00:35.769166', 'created_date': '2016-06-24'}