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['https://openalex.org/W2390927849', 'https://openalex.org/W2375108256', 'https://openalex.org/W2329067096', 'https://openalex.org/W2063697082', 'https://openalex.org/W2063538786', 'https://openalex.org/W2009035188', 'https://openalex.org/W2002540382', 'https://openalex.org/W2001930607', 'https://openalex.org/W1983031293', 'https://openalex.org/W1969018539'], 'abstract_inverted_index': {'Kv4': [0, 21, 32, 143, 196, 211, 232, 243, 354, 407, 640, 663, 799, 913, 1053, 1066, 1172, 1291, 1778, 1805, 1817, 3607], 'potassium': [1, 212, 423], 'channels': [2, 197, 213, 408, 560, 1011, 1173, 1779, 1818], 'regulate': [3, 214, 441, 1017], 'action': [4, 215, 479, 520], 'potentials': [5, 216, 521], 'in': [6, 26, 114, 131, 187, 217, 237, 325, 342, 398, 646, 651, 673, 723, 804, 824, 915, 976, 1003, 1153, 1421, 1460, 1470, 1733, 1757, 1767, 1819, 2298, 2323, 2336, 2346, 2503, 2722, 2733, 2788, 2860, 2951, 3011, 3036, 3149, 3154, 3227, 3262, 3343, 3395, 3401, 3423, 3440, 3457, 3471, 3481, 3489, 3497, 3505, 3515, 3522, 3592, 3645, 3682, 3753, 3757, 3841, 3850, 3875, 3969, 4002, 4085, 4131, 4165, 4233], 'neurons': [7, 218, 724, 825, 977, 3304, 3367, 3392, 3525], 'and': [8, 29, 61, 79, 100, 122, 153, 192, 198, 219, 240, 272, 290, 311, 333, 364, 403, 409, 435, 443, 570, 581, 649, 720, 823, 975, 1007, 1021, 1158, 1165, 1174, 1287, 1339, 1606, 1661, 1676, 1689, 1743, 1801, 1814, 1853, 1872, 1878, 2053, 2070, 2076, 2084, 2087, 2169, 2182, 2270, 2359, 2515, 2554, 2571, 2653, 2713, 2725, 2761, 2778, 2801, 2803, 2830, 2925, 2963, 3014, 3041, 3075, 3144, 3162, 3194, 3236, 3277, 3350, 3421, 3449, 3556, 3583, 3697, 3724, 3765, 3777, 3790, 3822, 3836, 3844, 3858, 3869, 3894, 3905, 3917, 3924, 3985, 4023, 4073, 4271, 4314, 4355], 'cardiac': [9, 220, 442, 465, 478, 647, 674, 805, 916, 1466, 1474, 1660], 'myocytes.': [10, 221], 'Co-expression': [11, 86, 222, 297, 3588], 'of': [12, 31, 82, 87, 93, 129, 158, 172, 195, 207, 223, 242, 293, 298, 304, 340, 369, 383, 406, 418, 452, 472, 476, 518, 563, 567, 653, 661, 671, 912, 1005, 1025, 1051, 1065, 1167, 1171, 1178, 1214, 1290, 1418, 1449, 1457, 1639, 1642, 1659, 1669, 1679, 1686, 1700, 1720, 1745, 1752, 1777, 1783, 1804, 1816, 2291, 2583, 2615, 2655, 2736, 2824, 2873, 2919, 2943, 2988, 3051, 3141, 3168, 3347, 3354, 3362, 3365, 3520, 3596, 3603, 3615, 3635, 3662, 3679, 3718, 3738, 3750, 3761, 3774, 3813, 3824, 3854, 3861, 3865, 3958, 3980, 3983, 4005, 4021, 4031, 4050, 4063, 4067, 4089, 4237, 4247, 4254, 4266, 4297, 4307, 4310, 4319, 4323, 4334, 4342, 4363, 4381], 'EF': [13, 224, 1304], 'hand-containing': [14, 225, 1305], 'Ca2+-binding': [15, 226, 1295, 1306], 'proteins': [16, 227, 2882, 3653], 'termed': [17, 228], 'KChIPs': [18, 73, 186, 229, 284, 397, 1281, 1293, 1450, 1727, 1786, 2360, 2405, 4151, 4346], 'with': [19, 230, 668, 795, 1341, 1610, 2105, 2305, 2353, 2388, 2491, 2549, 2555, 2638, 2649, 3017, 3067, 3213, 3232, 3255, 3317, 3419, 3433, 3533, 3665, 3685, 3714, 3740, 3801, 3805, 3816, 3826, 3834, 3884, 3896, 3929, 4008, 4012, 4157, 4163, 4190, 4227, 4250, 4280, 4339], 'pore-forming': [20, 231, 569], 'α': [22, 84, 233, 295, 572, 642, 1067, 1806], 'subunits': [23, 234, 573, 643, 1014, 1068, 1807], 'causes': [24, 89, 111, 235, 300, 322], 'changes': [25, 113, 236, 324], 'the': [27, 76, 105, 126, 135, 156, 170, 190, 204, 238, 287, 316, 337, 346, 367, 381, 401, 415, 473, 477, 516, 669, 1018, 1026, 1061, 1162, 1176, 1215, 1465, 1636, 1640, 1653, 1667, 1673, 1710, 1734, 1773, 1793, 1798, 1811, 2061, 2102, 2106, 2247, 2362, 2398, 2463, 2475, 2504, 2646, 2650, 2804, 2815, 2964, 3049, 3072, 3174, 3177, 3275, 3279, 3287, 3294, 3308, 3313, 3330, 3355, 3482, 3593, 3601, 3611, 3636, 3676, 3686, 3698, 3715, 3725, 3758, 3772, 3775, 3778, 3802, 3806, 3811, 3859, 3930, 3956, 3977, 3981, 4003, 4029, 4068, 4149, 4174, 4228, 4234, 4294, 4308, 4311, 4374], 'gating': [28, 239], 'amplitude': [30, 241, 1177], 'currents': [33, 244, 1420], '(An,': [34, 245], 'W.': [35, 246, 679, 703, 1625, 1844, 1850, 2044, 2050, 2160, 2166], 'F.,': [36, 247], 'Bowlby,': [37, 248], 'M.': [38, 249, 548, 614, 827, 847, 883, 1074, 1113, 1129, 1186, 1243, 1259, 1313, 1487, 1541, 1551, 1831, 1837, 1838, 2031, 2037, 2038, 2115, 2147, 2153, 2154, 2197, 2600, 4204], 'R.,': [39, 250], 'Betty,': [40, 251], 'M.,': [41, 252], 'Cao,': [42, 253, 1849, 2049, 2165], 'J.,': [43, 254], 'Ling,': [44, 255], 'H.': [45, 256, 606, 685, 705, 943], 'P.,': [46, 257], 'Mendoza,': [47, 258], 'G.,': [48, 259], 'Hinson,': [49, 260], 'J.': [50, 59, 64, 261, 270, 275, 493, 549, 598, 710, 729, 751, 785, 852, 885, 924, 964, 982, 994, 1076, 1103, 1188, 1233, 1315, 1357, 1438, 1497, 1543, 1826, 1848, 1854, 1936, 1985, 2007, 2026, 2048, 2054, 2117, 2142, 2164, 2170, 2200, 2227, 2375, 2446, 2603, 2675, 2691, 2891], 'W.,': [51, 57, 262, 268], 'Mattsson,': [52, 263], 'K.': [53, 63, 264, 274, 764, 768, 1828, 1929, 2028, 2144, 2419, 4100], 'I.,': [54, 265], 'Strassle,': [55, 266, 1845, 2045, 2161], 'B.': [56, 267, 449, 620, 707, 728, 1594, 1843, 2043, 2159], 'Trimmer,': [58, 269, 1856, 2056, 2172], 'S.,': [60, 271], 'Rhodes,': [62, 273, 1827, 2027, 2143], '(2000)': [65, 276], 'Nature': [66, 277], '403,': [67, 278], '553–556).': [68, 279], 'Here': [69, 280], 'we': [70, 281, 1664, 3609, 3688], 'show': [71, 282], 'that': [72, 124, 164, 283, 335, 375, 637, 1015, 1058, 1684, 1716, 1772, 1808, 2843, 3292, 3632, 4034, 4079, 4345], 'profoundly': [74, 285], 'affect': [75, 286, 4349, 4373], 'intracellular': [77, 288, 1674, 3642, 3677, 3794, 3814], 'trafficking': [78, 103, 289, 314, 1675, 1723], 'molecular': [80, 127, 193, 201, 291, 338, 404, 412, 1637, 1654, 1677, 1736, 1802], 'properties': [81, 128, 292, 339, 1737, 1795], 'Kv4.2': [83, 115, 130, 152, 175, 294, 326, 341, 363, 386, 1680, 1701, 1756, 2358, 2403, 2478, 2483, 3052, 3586, 3620, 3623, 3643, 3667, 3680, 3693, 3696, 3723, 3739, 3762, 3767, 3786, 3795, 3815, 3835, 3848, 3855, 3866, 3962, 3988, 4072, 4132, 4164, 4241, 4267, 4277, 4301, 4320, 4335, 4350, 4366, 4382], 'subunits.': [85, 296], 'KChIPs1–3': [88, 299, 4159, 4324], 'a': [90, 200, 301, 411, 469, 1047, 1226, 1342, 1471, 1583, 1696, 1714, 1721, 1730, 1956, 1963, 2324, 2412, 2543, 2620, 2633, 2639, 2762, 2789, 2931, 2969, 2995, 3263, 3300, 3318, 3344, 3506, 3646, 3746, 3754, 3852, 3999, 4017, 4040, 4080, 4144, 4170, 4244], 'dramatic': [91, 205, 302, 416, 1761, 1788, 3755], 'redistribution': [92, 303, 1699], 'Kv4.2,': [94, 305, 1746, 2874, 3719], 'releasing': [95, 306], 'intrinsic': [96, 307, 2505], 'endoplasmic': [97, 308, 1388, 1410], 'reticulum': [98, 309], 'retention': [99, 310], 'allowing': [101, 312], 'for': [102, 185, 203, 313, 396, 414, 798, 1755, 1858, 2058, 2174, 2357, 2728, 2791, 2811, 2880, 2975, 2998, 3025, 3071, 3146, 3199, 3219, 3269, 3414, 3460, 3491, 3562, 3585, 3650, 3695, 3722, 4046], 'to': [104, 181, 315, 392, 440, 1060, 1225, 1284, 1473, 1522, 1650, 1695, 1706, 1748, 2470, 2473, 2709, 2798, 2820, 2864, 2948, 3093, 3166, 3182, 3272, 3274, 3286, 3312, 3329, 3332, 3473, 3487, 3590, 3599, 3771, 3967, 3974, 4060, 4293, 4360], 'cell': [106, 317, 1022, 1711, 1799, 2476, 2657, 3659, 3784, 4175], 'surface.': [107, 318], 'KChIP': [108, 166, 208, 319, 377, 419, 1299, 1344, 1426, 1657, 1670, 1765, 1775, 3604], 'co-expression': [109, 320, 1427, 1671, 1685, 3605, 4064, 4124, 4322, 4341, 4370], 'also': [110, 321, 1424, 1578, 1728, 1797, 1953, 2099, 4142, 4182, 4337, 4348], 'fundamental': [112, 323], 'steady-state': [116, 327, 3970, 4331, 4378], 'expression': [117, 328, 660, 914, 1459, 2355, 3971, 3990, 3997, 4096, 4134, 4313, 4332, 4379], 'levels,': [118, 329], 'phosphorylation,': [119, 330, 1740], 'detergent': [120, 331, 1741, 2471, 2499, 2715, 2784, 2944, 3909], 'solubility,': [121, 332, 1742], 'stability': [123, 334, 3050], 'reconstitute': [125, 336], 'native': [132, 343, 1758, 4298], 'cells.': [133, 344, 1759, 3878], 'Interestingly,': [134, 345, 4028], 'KChIP4a': [136, 347, 1216, 3837, 3892, 3986, 4123, 4141, 4218, 4369], 'isoform,': [137, 348], 'which': [138, 349, 1462, 1608, 3703], 'exhibits': [139, 350], 'unique': [140, 351, 1227], 'effects': [141, 150, 167, 352, 361, 378, 531, 1213, 1348, 1668, 1770, 1789, 2509, 3602, 3960, 3982, 4014, 4025, 4092], 'on': [142, 151, 353, 362, 532, 1349, 1672, 1709, 1790, 2342, 2542, 2632, 2731, 2832, 2968, 2994, 3043, 3283, 3305, 3502, 3527, 3579, 3606, 3961, 3987, 4093, 4257, 4365], 'channel': [144, 355, 1028], 'gating,': [145, 356], 'does': [146, 357], 'not': [147, 358, 1646, 1692, 1791, 3839, 4054, 4058, 4126, 4372], 'exert': [148, 359], 'these': [149, 165, 360, 376, 1769], 'negatively': [154, 365], 'influences': [155, 366], 'impact': [157, 368, 1810], 'other': [159, 370, 1222, 2881, 3975, 4150], 'KChIPs.': [160, 371], 'We': [161, 372, 1043, 1682, 1912, 1952, 2023, 3630], 'provide': [162, 199, 373, 410], 'evidence': [163, 374, 635], 'occur': [168, 379], 'through': [169, 380], 'masking': [171, 382, 1719], 'an': [173, 182, 384, 393, 1915, 2737, 2821, 3133, 3862, 4225, 4251], 'N-terminal': [174, 385, 1063], 'hydrophobic': [176, 387], 'domain.': [177, 388], 'These': [178, 389], 'studies': [179, 390, 1340, 4088], 'point': [180, 391], 'essential': [183, 394, 1447, 3156, 3187, 3229], 'role': [184, 395, 1448], 'determining': [188, 399], 'both': [189, 400, 1285, 3851, 4071], 'biophysical': [191, 402, 1794], 'characteristics': [194, 405, 1024, 1678, 1749, 1803], 'basis': [202, 413, 4045], 'phenotype': [206, 417, 1641], 'knockout': [209, 420, 1517, 1644], 'mice.': [210, 421], 'Voltage-gated': [422, 582], 'or': [424, 565, 639, 2341, 2387, 2392, 2490, 2507, 2559, 2836, 3245, 3463, 3622, 3628, 3743, 3891, 4156, 4162, 4283, 4377], 'Kv': [425, 559, 1010], 'channels,': [426, 1702, 3608], 'specifically': [427], 'those': [428, 1753], 'mediating': [429], 'low': [430], 'threshold,': [431], 'rapidly': [432], 'inactivating': [433], 'Ito': [434, 467, 645, 672, 1006, 1467], 'IA': [436, 513, 650, 722], 'currents,': [437], 'are': [438, 561, 1219, 1294, 4274], 'known': [439, 4055], 'neuronal': [444, 1662, 3183], 'membrane': [445, 3652], 'excitability,': [446, 1663], 'respectively': [447], '(1Hille': [448], 'Ionic': [450], 'Channels': [451], 'Excitable': [453], 'Membranes.': [454], '3rd': [455], 'Ed.': [456], 'Sinauer': [457], 'Associates,': [458], 'Inc.,': [459, 587], 'Sunderland,': [460], 'MA2001:': [461], '136-139Google': [462], 'Scholar).': [463, 507, 558, 633, 792, 908, 1042, 1150, 1211, 1280, 1366, 1445, 1515, 1911, 1951, 2022, 2140, 2237, 2613, 2706, 2917, 3131, 3389, 4122, 4215], 'In': [464, 508, 2707, 4216], 'cells,': [466, 1155], 'is': [468, 802, 1645, 3938, 4053, 4057, 4278, 4291], 'major': [470], 'determinant': [471], 'falling': [474], 'phase': [475], 'potential': [480], '(2Oudit': [481], 'G.Y.': [482], 'Kassiri': [483], 'Z.': [484, 1890], 'Sah': [485], 'R.': [486, 760, 1105, 1235], 'Ramirez': [487], 'R.J.': [488], 'Zobel': [489], 'C.': [490, 683, 1619, 1835, 2035, 2151, 4202], 'Backx': [491], 'P.H.': [492, 1495], 'Mol.': [494, 4205], 'Cell.': [495, 1502, 1560, 4206], 'Cardiol.': [496], '2001;': [497, 996, 1503, 3382, 4208], '33:': [498], '851-872Abstract': [499], 'Full': [500, 838, 930, 932, 1506, 1508, 1564, 1566, 1942, 1944, 2013, 2015, 2381, 2432, 2434, 2452, 2454, 2681, 2697, 2699, 2897, 3122, 3124, 4113, 4115], 'Text': [501, 839, 931, 933, 1507, 1509, 1565, 1567, 1943, 1945, 2014, 2016, 2382, 2433, 2435, 2453, 2455, 2682, 2698, 2700, 2898, 3123, 3125, 4114, 4116], 'PDF': [502, 840, 934, 1510, 1568, 1946, 2017, 2383, 2436, 2456, 2683, 2701, 2899, 3126, 4117], 'PubMed': [503, 629, 697, 734, 756, 774, 790, 820, 841, 857, 873, 904, 935, 953, 970, 987, 999, 1038, 1095, 1146, 1207, 1276, 1334, 1443, 1511, 1569, 1601, 1631, 1907, 1947, 1990, 2018, 2136, 2206, 2233, 2384, 2437, 2457, 2609, 2684, 2702, 2900, 2913, 3105, 3127, 3385, 4118, 4211], 'Scopus': [504, 555, 630, 698, 716, 735, 775, 842, 874, 905, 936, 954, 971, 1039, 1096, 1147, 1208, 1277, 1335, 1363, 1512, 1570, 1602, 1632, 1908, 1948, 1991, 2019, 2137, 2207, 2234, 2438, 2458, 2610, 2703, 2914, 3106, 3128, 3386, 4119, 4212], '(170)': [505], 'Google': [506, 557, 632, 700, 718, 737, 757, 777, 791, 821, 844, 858, 876, 907, 938, 956, 973, 988, 1000, 1041, 1098, 1149, 1210, 1279, 1337, 1365, 1444, 1514, 1572, 1604, 1634, 1910, 1950, 1993, 2021, 2139, 2209, 2236, 2385, 2440, 2460, 2612, 2685, 2705, 2901, 2916, 3108, 3130, 3388, 4121, 4214], 'hippocampal': [509, 3088, 3169, 3175, 3223], 'pyramidal': [510], 'neurons,': [511], 'dendritic': [512, 721], 'can': [514, 1016], 'limit': [515], 'peak': [517], 'back-propagating': [519], 'as': [522, 524, 1575, 1581, 1647, 1886, 1969, 2589, 2665, 2875, 3299, 3370, 3808, 3940, 4065], 'well': [523], 'modulate': [525], 'incoming': [526], 'synaptic': [527], 'information,': [528], 'exerting': [529], 'profound': [530], 'information': [533], 'processing': [534, 2936], '(3Johnston': [535], 'D.': [536, 602, 612, 691, 1123, 1253, 1555, 2216], 'Hoffman': [537], 'D.A.': [538], 'Magee': [539], 'J.C.': [540], 'Poolos': [541], 'N.P.': [542], 'Watanabe': [543], 'S.': [544, 1141, 1271, 1840, 1855, 2040, 2055, 2156, 2171, 2220, 2421, 3378, 4102], 'Colbert': [545], 'C.M.': [546], 'Migliore': [547], 'Physiol.': [550, 711, 1358], '(Lond.).': [551, 712, 1359], '2000;': [552, 787, 901, 967, 984, 1092, 1204, 1331, 1987, 2010, 2133, 2203, 2449, 2606, 2694, 3119], '525:': [553], '75-81Crossref': [554], '(212)': [556, 1992, 3129], 'composed': [562], 'homo-': [564], 'heterotetramers': [566], 'transmembrane': [568], 'voltage-sensing': [571], '(4Chandy': [574], 'K.G.': [575], 'Gutman': [576], 'G.A.': [577, 3097], 'North': [578], 'R.A.': [579], 'Ligand-': [580], 'Ion': [583], 'Channels.': [584], 'CRC': [585], 'Press,': [586], 'Boca': [588], 'Raton,': [589], 'FL1995:': [590], '1-71Google': [591], 'Scholar,': [592, 701, 738, 758, 778, 845, 859, 877, 939, 957, 989, 1099, 1994, 2210, 2441, 2686, 2902, 3109], '5Coetzee': [593], 'W.A.': [594, 1590], 'Amarillo': [595], 'Y.': [596, 623, 762, 1127, 1257, 1491, 1493, 1617, 2000], 'Chiu': [597], 'Chow': [599], 'A.': [600, 610, 1142, 1272, 1433, 1832, 2032, 2148], 'Lau': [601], 'McCormack': [603], 'T.': [604, 742, 780, 1537], 'Moreno': [605], 'Nadal': [607], 'M.S.': [608], 'Ozaita': [609], 'Pountney': [611], 'Saganich': [613], 'Vega-Saenz': [615], 'de': [616], 'Miera': [617], 'E.': [618, 923, 961, 2193, 2222, 2596], 'Rudy': [619, 727], 'Ann.': [621], 'N.': [622, 746], 'Acad.': [624, 1138, 1268], 'Sci.': [625, 1139, 1269], '1999;': [626, 713, 771, 1598], '868:': [627], '233-285Crossref': [628], '(977)': [631], 'Available': [634], 'suggests': [636], 'Shal': [638], 'family': [641, 664, 800, 1050], 'underlie': [644], 'myocytes,': [648], 'dendrites': [652], 'many': [654], 'central': [655], 'nervous': [656], 'system': [657], 'neurons.': [658, 3170], 'The': [659, 1212, 1297, 1446, 1760, 2480, 2783, 2978, 3031, 3171, 3222, 3568, 3792, 4044, 4288, 4304], 'specific': [662, 797], 'mRNAs': [665], 'correlates': [666], 'precisely': [667, 3705], 'level': [670, 3972, 4380], 'myocytes': [675, 806, 917], '(6Dixon': [676], 'J.E.': [677], 'Shi': [678, 1930], 'Wang': [680, 866], 'H.S.': [681], 'McDonald': [682], 'Yu': [684], 'Wymore': [686], 'R.S.': [687], 'Cohen': [688], 'I.S.': [689], 'McKinnon': [690], 'Circ.': [692, 815, 948], 'Res.': [693, 816, 949, 3101], '1996;': [694, 1904, 1939, 2429, 4110], '79:': [695, 732], '659-668Crossref': [696], '(393)': [699], '7Guo': [702], 'Xu': [704, 942], 'London': [706], 'Nerbonne': [708, 813, 946, 980, 992], 'J.M.': [709, 814, 947, 981, 993, 1559], '521:': [714], '587-599Crossref': [715], '(191)': [717], 'Scholar)': [719, 822, 974, 1001, 2386], '(8Serodio': [725], 'P.': [726, 1115, 1245], 'Neurophysiol.': [730], '1998;': [731, 753, 950, 1035, 1628], '1081-1091Crossref': [733], '(300)': [736], '9Song': [739], 'W.J.': [740], 'Tkatch': [741], 'Baranauskas': [743, 781], 'G.': [744, 782, 889, 1080, 1192, 1319, 1931, 2121, 2368, 2417, 2668, 2884, 4098], 'Ichinohe': [745], 'Kitai': [747], 'S.T.': [748, 3111, 3376], 'Surmeier': [749, 783], 'D.J.': [750, 784], 'Neurosci.': [752, 770, 786, 853, 983, 995, 1439, 4207], '18:': [754], '3124-3137Crossref': [755], '10Shibata': [759], 'Wakazono': [761], 'Nakahira': [763, 2418, 4099], 'Trimmer': [765, 809, 850, 896, 1087, 1199, 1326, 1901, 1934, 2128, 2198, 2225, 2373, 2426, 2444, 2601, 2673, 2689, 2889, 3116, 3379, 4107], 'J.S.': [766, 810, 851, 897, 1031, 1088, 1200, 1327, 1902, 1935, 2129, 2199, 2226, 2374, 2427, 2445, 2602, 2674, 2690, 2890, 3117, 3380, 4108], 'Ikenaka': [767], 'Dev.': [769], '21:': [772, 997], '87-93Crossref': [773], '(34)': [776], '11Tkatch': [779], '20:': [788, 985], '579-588Crossref': [789], 'Robust': [793], 'staining': [794, 2552, 2582, 3613, 3644, 3661, 3709, 3721, 3768, 3787, 3857, 4038, 4186, 4219], 'antibodies': [796, 1875, 1883, 2179, 2274, 2284, 2519, 3459, 3485, 3668, 3898, 3933], 'members': [801], 'observed': [803, 1754, 2511, 3670, 4048, 4084, 4275, 4338], '(12Barry': [807], 'D.M.': [808, 941], 'Merlie': [811], 'J.P.': [812, 1972, 1998], '1995;': [817, 854], '77:': [818], '361-369Crossref': [819], '(13Sheng': [826], 'Tsaur': [828], 'M.L.': [829, 861], 'Jan': [830, 832], 'Y.N.': [831], 'L.Y.': [833], 'Neuron.': [834, 2428, 3118, 4109], '1992;': [835], '9:': [836], '271-284Abstract': [837], '(400)': [843], '14Maletic-Savatic': [846], 'Lenn': [848], 'N.J.': [849], '15:': [855], '3840-3851Crossref': [856], '15Tsaur': [860], 'Chou': [862], 'C.C.': [863], 'Shih': [864], 'Y.H.': [865], 'H.L.': [867], 'FEBS': [868], 'Lett.': [869], '1997;': [870, 927], '400:': [871], '215-220Crossref': [872], '(52)': [875], '16An': [878], 'W.F.': [879, 1070, 1135, 1182, 1265, 1309, 2111], 'Bowlby': [880, 1071, 1183, 1310, 2112], 'M.R.': [881, 1072, 1184, 1311, 2113], 'Betty': [882, 1073, 1112, 1185, 1242, 1312, 2114], 'Cao': [884, 1075, 1102, 1187, 1232, 1314, 2116], 'Ling': [886, 1077, 1189, 1316, 2118], 'H.P.': [887, 1078, 1190, 1317, 2119], 'Mendoza': [888, 1079, 1191, 1318, 2120], 'Hinson': [890, 1081, 1193, 1320, 2122], 'J.W.': [891, 1082, 1194, 1321, 2123], 'Mattsson': [892, 1083, 1195, 1322, 2124], 'K.I.': [893, 1084, 1109, 1196, 1239, 1323, 1533, 2125], 'Strassle': [894, 1085, 1197, 1324, 1895, 2126], 'B.W.': [895, 1086, 1198, 1325, 1896, 2127], 'Rhodes': [898, 1089, 1130, 1201, 1260, 1328, 1899, 1932, 2130, 2422, 4103], 'K.J.': [899, 1090, 1117, 1131, 1202, 1247, 1261, 1329, 1900, 1933, 2131, 2423, 4104], 'Nature.': [900, 1091, 1203, 1330, 1597, 2132], '403:': [902, 1093, 1205, 1332, 2134], '553-556Crossref': [903, 1094, 1206, 1333, 2135], '(834)': [906, 1097, 1209, 1336, 2138], 'Moreover,': [909, 3656, 4358], 'experimental': [910], 'knockdown': [911], '(17Johns': [918], 'D.C.': [919, 963], 'Nuss': [920], 'H.B.': [921], 'Marban': [922, 960], 'Biol.': [925, 1937, 2008, 2202, 2229, 2376, 2447, 2605, 2676, 2692, 2892], 'Chem.': [926, 1938, 2009, 2377, 2448, 2677, 2693, 2893], '272:': [928], '31598-31603Abstract': [929], '(144)': [937], '18Barry': [940], 'Schuessler': [944], 'R.B.': [945, 1481], '83:': [951], '560-567Crossref': [952], '(253)': [955], '19Hoppe': [958], 'U.C.': [959], 'Johns': [962], 'Clin.': [965], 'Invest.': [966], '105:': [968], '1077-1084Crossref': [969], '(64)': [972, 1364], '(20Malin': [978], 'S.A.': [979, 991], '5191-5199Crossref': [986], '21Malin': [990], '8004-8014Crossref': [998], 'results': [1002], 'suppression': [1004], 'IA,': [1008], 'respectively.Many': [1009], 'contain': [1012], 'auxiliary': [1013], 'biophysical,': [1019], 'biochemical,': [1020], 'biological': [1023, 1800], 'resultant': [1027], 'complexes': [1029], '(22Trimmer': [1030], 'Curr.': [1032], 'Opin.': [1033], 'Neurobiol.': [1034], '8:': [1036], '370-374Crossref': [1037], '(95)': [1040], 'have': [1044, 1665, 1823], 'recently': [1045, 1824, 2024], 'described': [1046, 1887, 1970, 2186, 2590, 2666, 2878, 3371, 4193], 'highly': [1048], 'related': [1049], 'four': [1052, 1303], 'Channel': [1054], 'Interacting': [1055], 'Proteins': [1056, 3521], '(KChIPs1–4)': [1057], 'binds': [1059], 'cytoplasmic': [1062, 1722, 1918, 2492], 'domain': [1064, 1919, 2933], '(16An': [1069, 1181, 1308, 2110], '23Holmqvist': [1100], 'M.H.': [1101, 1231], 'Hernandez-Pineda': [1104, 1234], 'Jacobson': [1106, 1236], 'M.D.': [1107, 1237], 'Carroll': [1108, 1238], 'Sung': [1110, 1240], 'M.A.': [1111, 1241], 'Ge': [1114, 1244], 'Gilbride': [1116, 1246], 'Brown': [1118, 1248], 'M.E.': [1119, 1121, 1249, 1251], 'Jurman': [1120, 1250], 'Lawson': [1122, 1252], 'Silos-Santiago': [1124, 1254], 'I.': [1125, 1255, 1545, 1829, 2029, 2145], 'Xie': [1126, 1256], 'Covarrubias': [1128, 1258], 'Distefano': [1132, 1262], 'P.S.': [1133, 1263], 'An': [1134, 1264, 2255], 'Proc.': [1136, 1266], 'Natl.': [1137, 1267], 'U.': [1140, 1270], '2002;': [1143, 1273, 1360, 1440, 1561, 2230], '99:': [1144, 1274], '1035-1040Crossref': [1145, 1275], '(152)': [1148, 1278, 2459, 2704], 'When': [1151], 'co-expressed': [1152, 4279], 'heterologous': [1154, 1422], 'KChIP1,': [1156, 1687, 3625, 3741, 4281], 'KChIP2,': [1157, 1688, 3626, 3742, 3901], 'KChIP3': [1159, 1516, 1576, 3744, 3889, 3922], 'dramatically': [1160, 1809], 'alter': [1161], 'inactivation': [1163, 1170, 1350], 'kinetics': [1164], 'rate': [1166], 'recovery': [1168], 'from': [1169, 1221, 1703, 2101, 2246, 2262, 2277, 2286, 2321, 2660, 3138, 3203, 4148], 'boost': [1175], 'obtained': [1179, 2245, 2261, 2276], 'current': [1180, 1468], 'splice': [1217], 'variant': [1218], 'distinct': [1220, 3873, 4147, 4264], 'KChIPs,': [1223, 3976, 4343], 'due': [1224, 3966, 4059], 'N': [1228], 'terminus': [1229], '(23Holmqvist': [1230], 'may': [1282, 1717, 4347], 'contribute': [1283], 'constitutive': [1286], 'dynamic': [1288], 'regulation': [1289, 1417, 1658], 'channels.': [1292, 1681], 'proteins.': [1296], 'conserved': [1298], 'core': [1300], 'region': [1301], 'contains': [1302], 'motifs': [1307], 'Scholar),': [1338, 1573, 1605, 1635, 2461], 'minimal': [1343], 'isoform': [1345], 'suggest': [1346, 1771], 'Ca2+-dependent': [1347], '(24Patel': [1351], 'S.P.': [1352], 'Campbell': [1353], 'D.L.': [1354, 2906], 'Strauss': [1355], 'H.C.': [1356, 1477], '545:': [1361], '5-11Crossref': [1362], 'Cyclic': [1367], 'AMP-dependent': [1368, 1378, 1400], 'protein': [1369, 1379, 1401, 2109, 2989, 3057, 3701, 4249], 'kinase': [1370], '(PKA)': [1371], '1The': [1372], 'abbreviations': [1373, 1395], 'used': [1374, 1396, 2859], 'are:': [1375, 1397], 'PKA,': [1376, 1398], 'cyclic': [1377, 1399], 'kinase;': [1380, 1402], 'AP,': [1381, 1403], 'alkaline': [1382, 1404, 3020], 'phosphatase;': [1383, 1405], 'PBS,': [1384, 1406, 3420, 3516], 'phosphate-buffered': [1385, 1407, 3402], 'saline;': [1386, 1408], 'ER,': [1387, 1409, 3687], 'reticulum;': [1389, 1411], 'EGFP,': [1390, 1412], 'enhanced': [1391, 1413], 'green': [1392, 1414, 2557], 'fluorescent': [1393, 1415], 'protein.1The': [1394], 'protein.': [1416], 'Kv4.2-encoded': [1419], 'cells': [1423, 2295, 2586, 2616, 2662, 2712, 2717, 3061, 3617, 3639, 3664, 3691, 3780, 3832, 3846, 3880, 3914, 4007, 4033, 4069, 4167, 4181, 4239], 'requires': [1425], '(25Schrader': [1428], 'L.A.': [1429], 'Anderson': [1430, 1973], 'A.E.': [1431, 1974, 1996], 'Mayne': [1432], 'Pfaffinger': [1434, 1981, 2003], 'P.J.': [1435, 1982, 2004], 'Sweatt': [1436, 1983, 2005], 'J.D.': [1437, 1613, 1984, 2006], '22:': [1441], '10123-10133Crossref': [1442], 'was': [1451, 2098, 2244, 2260, 2485, 2510, 2587, 2786, 2809, 2818, 2858, 2921, 2946, 2961, 2966, 2981, 3136, 3180, 3327, 3358, 3368, 3669, 3681, 3797, 3964, 3991, 4083, 4220], 'acutely': [1452], 'demonstrated': [1453], 'by': [1454, 2361, 2487, 2923, 2983, 2992, 3053, 3078, 3211, 3479, 3572, 3810], 'genetic': [1455], 'ablation': [1456], 'KChIP2': [1458, 3887, 3920, 3984, 3996], 'mice,': [1461], 'completely': [1463], 'eliminated': [1464], 'resulting': [1469, 2805], 'predisposition': [1472], 'arrhythmias': [1475], '(26Kuo': [1476], 'Cheng': [1478], 'C.F.': [1479], 'Clark': [1480], 'Lin': [1482, 1484], 'J.J.': [1483, 4200], 'J.L.': [1485], 'Hoshijima': [1486], 'Nguyen-Tran': [1488], 'V.T.': [1489], 'Gu': [1490], 'Ikeda': [1492], 'Chu': [1494], 'Ross': [1496], 'Giles': [1498], 'W.R.': [1499], 'Chien': [1500], 'K.R.': [1501], '107:': [1504], '801-813Abstract': [1505], '(383)': [1513], 'mice': [1518, 2103], 'exhibit': [1519, 3872, 4243], 'reduced': [1520], 'sensitivity': [1521], 'pain': [1523], '(27Cheng': [1524], 'H.Y.': [1525], 'Pitcher': [1526], 'G.M.': [1527], 'Laviolette': [1528], 'S.R.': [1529], 'Whishaw': [1530], 'I.Q.': [1531], 'Tong': [1532], 'Kockeritz': [1534], 'L.K.': [1535], 'Wada': [1536], 'Joza': [1538], 'N.A.': [1539], 'Crackower': [1540], 'Goncalves': [1542], 'Sarosi': [1544], 'Woodgett': [1546], 'J.R.': [1547, 1596], 'Oliveira-dos-Santos': [1548], 'A.J.': [1549], 'Ikura': [1550], 'van': [1552], 'der': [1553], 'Kooy': [1554], 'Salter': [1556], 'M.W.': [1557], 'Penninger': [1558], '108:': [1562, 3383], '31-43Abstract': [1563], '(238)': [1571], 'although': [1574, 4179], 'has': [1577, 2876], 'been': [1579, 2877], 'identified': [1580], 'DREAM,': [1582], 'calcium-dependent': [1584], 'transcription': [1585], 'factor': [1586], '(28Carrion': [1587], 'A.M.': [1588, 2189, 2592], 'Link': [1589], 'Ledo': [1591], 'F.': [1592, 1851, 2051, 2167, 4198], 'Mellstrom': [1593], 'Naranjo': [1595], '398:': [1599], '80-84Crossref': [1600], '(488)': [1603], 'calsenilin,': [1607], 'interacts': [1609], 'presenilins': [1611], '(29Buxbaum': [1612], 'Choi': [1614], 'E.K.': [1615], 'Luo': [1616], 'Lilliehook': [1618], 'Crowley': [1620], 'A.C.': [1621], 'Merriam': [1622], 'D.E.': [1623, 3113, 3374], 'Wasco': [1624], 'Nat.': [1626], 'Med.': [1627], '4:': [1629], '1177-1181Crossref': [1630], '(301)': [1633], 'pathophysiology': [1638], 'this': [1643, 3842, 4047], 'clear.In': [1648], 'order': [1649], 'better': [1651], 'understand': [1652], 'mechanisms': [1655], 'underlying': [1656], 'investigated': [1666], 'found': [1683, 3631], 'KChIP3,': [1690, 3627, 3903], 'but': [1691, 1796, 3804, 4056], 'KChIP4a,': [1693, 3906], 'leads': [1694], 'conspicuous': [1697], 'subcellular': [1698, 3759, 4145], 'being': [1704, 1707], 'ER-retained': [1705, 3651], 'expressed': [1708, 4070, 4153, 4160, 4248], 'surface,': [1712], 'via': [1713], 'mechanism': [1715], 'involve': [1718], 'and/or': [1724, 2404], 'solubility': [1725], 'determinant.': [1726], 'induce': [1729, 1787], 'striking': [1731], 'transformation': [1732], 'overall': [1735], '(expression': [1738], 'level,': [1739], 'stability)': [1744], 'leading': [1747], 'more': [1750], 'typical': [1751, 3649], 'differences': [1762, 2868, 3968], 'between': [1763, 2512, 2869], 'different': [1764, 2870], 'isoforms': [1766], 'inducing': [1768], 'precise': [1774], 'composition': [1776], 'impacts': [1780], 'diverse': [1781], 'aspects': [1782], 'function.': [1784], 'Thus': [1785], 'only': [1792], 'function,': [1812], 'abundance,': [1813], 'distribution': [1815, 3760, 4146, 4172], 'excitable': [1820], 'cells.EXPERIMENTAL': [1821], 'PROCEDURESAntibodies—We': [1822], '2K.': [1825, 2025, 2141], 'Carroll,': [1830, 2030, 2146], 'Sung,': [1833, 2033, 2149], 'L.': [1834, 1841, 1846, 1894, 2034, 2041, 2046, 2150, 2157, 2162], 'Doliveira,': [1836, 2036, 2152], 'Monaghan,': [1839, 2039, 2155], 'Burke,': [1842, 2042, 2158], 'Buchwalder,': [1847, 2047, 2163], 'An,': [1852, 2052, 2168], 'submitted': [1857, 2057, 2173], 'publication.': [1859, 2059, 2175], 'generated': [1860, 1885, 1914, 1955, 2060, 2100], 'anti-Kv4.2': [1861, 1916], 'ectodomain': [1862], '(S1-S2': [1863], 'linker,': [1864], 'amino': [1865], 'acids': [1866, 1921], '209–225': [1867], 'CGSSPGHIKELPSGERY)': [1868], 'rabbit': [1869, 1924, 1959, 2257, 2494], 'polyclonal': [1870, 1925, 1960, 2258, 2495, 2956], '(Kv4.2e)': [1871], 'mouse': [1873, 2064, 2093, 2177, 2239, 2271, 2466], 'monoclonal': [1874, 1882, 2065, 2094, 2178, 2240, 2467], '(K57/1': [1876], '(IgG1)': [1877, 2069, 2075, 2184], 'K57/40': [1879], '(IgG3)).': [1880], 'Mouse': [1881], 'were': [1884, 2185, 2275, 2285, 2296, 2334, 2351, 2406, 2520, 2537, 2564, 2617, 2663, 2718, 3007, 3033, 3065, 3090, 3209, 3225, 3260, 3310, 3338, 3393, 3431, 3454, 3466, 3500, 3530, 3570, 3881, 3927, 4325, 4336], 'previously': [1888, 1913, 1954, 2187, 2879, 3253, 3295, 3372, 4192], '(31Bekele-Arcuri': [1889], 'Matos': [1891], 'M.F.': [1892], 'Manganas': [1893, 2190, 2593], 'Monaghan': [1897], 'M.M.': [1898], 'Neuropharmacology.': [1903], '35:': [1905], '851-865Crossref': [1906], '(101)': [1909], 'C-terminal': [1917], '(amino': [1920], '484–502': [1922], 'CLEKTTNHEFVDEQVFEES)': [1923], 'antibody': [1926, 1961, 2241, 2259, 2468, 2496, 2958], 'Kv4.2C': [1927, 2957], '(32Nakahira': [1928], '271:': [1940], '7084-7089Abstract': [1941], '(125)': [1949], 'phosphorylation': [1957, 2871], 'site-specific': [1958], 'against': [1962], 'synthetic': [1964], 'peptide': [1965], 'containing': [1966, 2742, 3158, 3189, 3511], 'phosphoserine-552': [1967], '(CT-PKA)': [1968], '(33Adams': [1971], 'Varga': [1975], 'A.W.': [1976], 'Dineley': [1977], 'K.T.': [1978], 'Cook': [1979, 2001], 'R.G.': [1980, 2002], 'Neurochem.': [1986], '75:': [1988], '2277-2287Crossref': [1989], '34Anderson': [1995], 'Adams': [1997], 'Qian': [1999], '275:': [2011, 2450, 2695], '5337-5346Abstract': [2012], '(113)': [2020], 'following': [2062, 2498], 'anti-KChIP': [2063], 'antibodies:': [2066], 'anti-KChIP1': [2067], '(K55/7': [2068], 'K55/29': [2071], '(IgG2a)),': [2072], 'anti-KChIP2': [2073], '(K60/41': [2074], 'K60/73': [2077], '(IgG1)),': [2078, 2086], 'anti-KChIP3': [2079], '(K66/29': [2080], '(IgG2a),': [2081, 2083, 2097], 'K66/38': [2082], 'K90A/19': [2085], 'anti-KChIP4': [2088], '(1G2': [2089], '(IgG2a)).': [2090], 'A': [2091, 3005], 'pan-KChIP': [2092], 'antibody,': [2095, 3477], 'K55/82': [2096], 'immunized': [2104], 'KChIP1': [2107, 3885, 3918], 'fusion': [2108], 'Anti-PSD-95': [2176], 'K28/43': [2180], '(IgG2a)': [2181, 2243], 'K28/86': [2183], '(35Tiffany': [2188, 2591], 'L.N.': [2191, 2443, 2594, 2688], 'Kim': [2192, 2595], 'Hsueh': [2194, 2597], 'Y.P.': [2195, 2598], 'Sheng': [2196, 2599], 'Cell': [2201, 2228, 2604], '148:': [2204, 2607], '147-158Crossref': [2205, 2608], '(149)': [2208, 2611], '36Rasband': [2211], 'M.N.': [2212], 'Park': [2213], 'E.W.': [2214], 'Zhen': [2215], 'Arbuckle': [2217], 'M.I.': [2218], 'Poliak': [2219], 'Peles': [2221], 'Grant': [2223], 'S.G.': [2224], '159:': [2231], '663-672Crossref': [2232], '(71)': [2235], 'Anti-GAD': [2238], 'GAD-6': [2242], 'Developmental': [2248], 'Studies': [2249], 'Hybridoma': [2250], 'Bank,': [2251], 'Iowa': [2252], 'City,': [2253], 'IA.': [2254], 'anti-calnexin': [2256], 'Stressgen': [2263], '(Vancouver,': [2264], 'British': [2265], 'Columbia,': [2266], 'Canada).': [2267], 'Fluorescent': [2268], 'species-specific': [2269], 'isotype-specific': [2272], 'secondary': [2273, 2283, 3484], 'Molecular': [2278, 4235], 'Probes': [2279], '(Eugene,': [2280], 'OR).': [2281], 'Horseradish-peroxidase-conjugated': [2282], 'ICN': [2287], '(Aurora,': [2288], 'OH).Immunofluorescence': [2289], 'Analyses': [2290], 'Transfected': [2292], 'COS-1': [2293, 2585, 2656, 2711, 3060, 3616, 3638, 3690, 3877, 3879, 3913, 4166], 'Cells—COS-1': [2294], 'grown': [2297], "Dulbecco's": [2299], 'modified': [2300], "Eagle's": [2301], 'medium': [2302, 3157, 3179, 3185, 3188, 3230, 3357], '(Invitrogen)': [2303, 2391], 'supplemented': [2304, 3231], '10%': [2306, 3159, 3233], 'newborn': [2307], 'calf': [2308, 3018], 'serum': [2309, 3161, 3235], '(Hyclone': [2310], 'Laboratories,': [2311], 'Logan,': [2312], 'UT),': [2313], '50': [2314, 2317], 'units/ml': [2315], 'penicillin,': [2316], 'μg/ml': [2318, 2767, 2770, 2773, 2776], 'streptomycin': [2319], '(both': [2320], 'Invitrogen)': [2322], 'humidified': [2325, 3264, 3345], 'incubator': [2326, 3265], 'at': [2327, 2794, 2972, 3001, 3028, 3216, 3266, 3340, 3558, 3565, 3745, 4016, 4026, 4042, 4135, 4269, 4383], '37': [2328, 3029, 3217, 3341], '°C': [2329, 2974, 3218, 3342], 'under': [2330, 2539, 2566], '5%': [2331, 2855, 3267, 3351], 'CO2.': [2332, 3352], 'Cells': [2333, 2350, 2401, 2536, 2548, 3453, 3465], 'maintained': [2335, 3339], 'plastic': [2337, 2347, 3247, 3306, 3528], 'tissue': [2338, 3151, 3248, 3289], 'culture': [2339, 3135, 3152, 3249, 3290, 3356], 'dishes': [2340, 3250, 3529], 'poly-l-lysine-coated': [2343], 'glass': [2344], 'coverslips': [2345, 3242, 3280, 3499], 'Petri': [2348], 'dishes.': [2349], 'transfected': [2352, 2661, 3779, 3876, 3883], 'mammalian': [2354], 'vectors': [2356], 'calcium': [2363], 'phosphate': [2364], 'precipitation': [2365], 'method': [2366], '(37Shi': [2367, 2667, 2883], 'Kleinklaus': [2369, 2669, 2885], 'A.K.': [2370, 2670, 2886], 'Marrion': [2371, 2671, 2887], 'N.V.': [2372, 2672, 2888], '1994;': [2378, 2678, 2894], '269:': [2379, 2679, 2895], '23204-23211Abstract': [2380, 2680, 2896], 'LipofectAMINE': [2389], '2000': [2390], 'Polyfect': [2393], '(Qiagen)': [2394], 'transfection': [2395], 'reagents': [2396], 'using': [2397, 2411, 2522, 2645, 2927], "manufacturers'": [2399], 'protocols.': [2400], 'expressing': [2402, 3618, 3692, 3847, 3915, 4240], 'stained': [2407, 3895, 3928], '48': [2408], 'h': [2409, 3000, 3027, 3063, 3271, 3462], 'post-transfection': [2410, 3064], 'surface': [2413, 2477, 2551, 3660, 3785, 3856, 3989, 4010, 4037, 4095, 4133, 4312, 4367], 'immunofluorescence': [2414, 2541, 2581, 3612, 3708], 'protocol': [2415], '(38Shi': [2416, 4097], 'Hammond': [2420, 4101], 'Schechter': [2424, 4105], 'L.E.': [2425, 4106], '16:': [2430, 4111], '843-852Abstract': [2431, 4112], '(333)': [2439, 4120], '39Manganas': [2442, 2687], '29685-29693Abstract': [2451, 2696], 'applying': [2462], 'ectodomain-directed': [2464], 'K57/1': [2465], 'prior': [2469, 3165], 'permeabilization': [2472], 'detect': [2474], 'pool.': [2479], 'total': [2481, 2556, 3055], 'cellular': [2482, 3056], 'pool': [2484, 3678, 3796, 3864, 4246], 'detected': [2486, 2521], 'EGFP': [2488, 3941], 'fluorescence': [2489, 2558, 3942], 'directed': [2493], 'Kv4.2N': [2497], 'permeabilization.': [2500, 3910], 'No': [2501], 'difference': [2502], 'localization': [2506, 3717, 3937, 3963], 'KChIP-induced': [2508], 'wild': [2513], 'type': [2514], 'EGFP-tagged': [2516], 'Kv4.2.Bound': [2517], 'primary': [2518, 3085, 3458, 3476], 'Alexa': [2523, 2531], '594-conjugated': [2524], 'goat': [2525, 2533], 'anti-mouse': [2526], 'IgG': [2527], 'and,': [2528], 'if': [2529], 'needed,': [2530], '488-conjugated': [2532], 'anti-rabbit': [2534], 'IgG.': [2535], 'viewed': [2538], 'indirect': [2540], 'Zeiss': [2544, 2621, 2634], 'Axioskop': [2545, 2635], '2': [2546, 2636, 2772, 2792], 'microscope.': [2547], 'detectable': [2550, 3658, 4009, 4036, 4129], '(red)': [2553], 'staining,': [2560], 'indicating': [2561], 'successful': [2562], 'transfection,': [2563], 'scored': [2565], 'narrow': [2567], 'wavelength': [2568], 'Texas': [2569], 'Red': [2570], 'fluorescein': [2572], 'filter': [2573], 'sets,': [2574], 'respectively.': [2575], 'For': [2576, 2813, 3303], 'some': [2577], 'experiments': [2578], 'standard': [2579], 'double': [2580, 3720], 'permeabilized': [2584, 3422, 3912], 'performed': [2588, 2664, 2922, 3369], 'Images': [2614], 'captured': [2618], 'into': [2619], 'Axiocam': [2622], '(Oberkochen,': [2623], 'Germany)': [2624], 'cooled': [2625], 'CCD': [2626], '24-bit': [2627], 'color': [2628], 'digital': [2629], 'camera': [2630], 'mounted': [2631, 3501], 'microscope': [2637, 3503], '100×,': [2640], '1.4': [2641], 'numerical': [2642], 'aperture': [2643], 'objective,': [2644], 'software': [2647], 'supplied': [2648], 'camera.Immunoprecipitation,': [2651], 'SDS-PAGE,': [2652], 'Immunoblotting—Analyses': [2654], 'lysates': [2658], 'prepared': [2659, 3091, 3137], 'brief,': [2708], 'harvest': [2710], 'prepare': [2714], 'lysates,': [2716], 'first': [2719], 'washed': [2720, 3008, 3417, 3468, 3531], 'twice': [2721, 3418, 3532], 'ice-cold': [2723, 2738, 2952, 3534], 'PBS': [2724], 'then': [2726, 3015, 3034, 3076, 3278, 3455, 3467], 'lysed': [2727], '5': [2729, 2752, 3147, 3547, 3550], 'min': [2730, 2793, 3564], 'ice': [2732], '1': [2734, 2758, 2769, 2949, 2999, 3256, 3333, 3492, 3764, 3789], 'ml': [2735, 2950], 'lysis': [2739, 2953, 3012], 'buffer': [2740, 2829, 3013, 3040], 'solution': [2741, 3510, 3536], 'TBS': [2743], '(10': [2744], 'mm': [2745, 2748, 2753, 2759, 2780, 3196, 3409, 3442, 3447, 3538, 3541, 3544, 3548, 3551], 'Tris,': [2746, 3443], '150': [2747, 3446], 'NaCl,': [2749, 3407, 3448, 3539], 'pH': [2750, 3412, 3444, 3517, 3553], '8.0),': [2751], 'EDTA,': [2754], '0.4%': [2755], 'Triton': [2756, 3426, 3451], 'X-100,': [2757], 'iodoacetamide,': [2760], 'protease': [2763], 'inhibitor': [2764], 'mixture': [2765, 2965], '(2': [2766], 'aprotinin,': [2768], 'leupeptin,': [2771], 'antipain,': [2774], '10': [2775, 3408, 3947], 'benzamidine,': [2777], '0.2': [2779], 'phenylmethylsulfonyl': [2781], 'fluoride).': [2782], 'lysate': [2785, 2817, 2945], 'centrifuged': [2787, 3557], 'microcentrifuge': [2790], '13,000': [2795], '×': [2796, 3560], 'g': [2797, 3561], 'pellet': [2799], 'nuclei': [2800], 'debris,': [2802], 'supernatant': [2806], '(cleared': [2807], 'lysate)': [2808], 'saved': [2810], 'analysis.': [2812], 'immunoblots,': [2814], 'cleared': [2816], 'added': [2819, 3328], 'equal': [2822], 'volume': [2823], '2×': [2825], 'reducing': [2826, 3037, 3574], 'SDS': [2827, 2861, 3038, 3575, 4258], 'sample': [2828, 3039, 3576], 'fractionated': [2831], '9': [2833], '(for': [2834, 2838], 'Kv4.2)': [2835], '15%': [2837], 'KChIPs)': [2839], 'SDS-polyacrylamide': [2840, 3045], 'gels.': [2841], 'Note': [2842], '"lauryl': [2844], 'sulfate"': [2845], '(Sigma': [2846], 'L-5750;': [2847], '69%': [2848], 'lauryl': [2849], 'sulfate': [2850], '(SDS),': [2851], '26%': [2852], 'myristyl': [2853], 'sulfate,': [2854], 'cetyl': [2856], 'sulfate)': [2857], 'gel': [2862], 'recipes': [2863], 'accentuate': [2865], 'electrophoretic': [2866], 'mobility': [2867], 'states': [2872], '40Ward': [2903], 'G.E.': [2904], 'Garbers': [2905], 'Vacquier': [2907], 'V.D.': [2908], 'Science.': [2909], '1985;': [2910], '227:': [2911], '768-770Crossref': [2912], '(62)': [2915], 'Quantitation': [2918], 'immunoreactivity': [2920], 'densitometry': [2924], 'analysis': [2926], 'Image': [2928, 3950], 'J': [2929], 'software,': [2930], 'public': [2932], 'Java': [2934], 'image': [2935], 'program': [2937], '(rsb.info.nih.gov/ij/index.html).For': [2938], 'immunoprecipitation': [2939], 'reactions,': [2940], '200': [2941], 'μl': [2942, 2987], 'diluted': [2947], 'buffer.': [2954], 'Affinity-purified': [2955], '(5': [2959], 'μg)': [2960], 'added,': [2962], 'incubated': [2967, 3016, 3261, 3456], 'tube': [2970, 2996], 'rotator': [2971, 2997], '4': [2973, 3002, 3270, 3566], '16': [2976, 3026], 'h.': [2977, 3493], 'antibody-antigen': [2979], 'complex': [2980], 'immobilized': [2982], 'adsorption': [2984], 'onto': [2985, 3239], '15': [2986, 3220, 3415], 'A-agarose': [2990], '(Pierce)': [2991], 'incubation': [2993, 3480], '°C.': [3003, 3030, 3567], 'Protein': [3004], 'beads': [3006, 3032], 'six': [3009], 'times': [3010, 3074, 3470], 'intestinal': [3019], 'phosphatase': [3021], '(AP,': [3022], '0.1': [3023, 3195, 3512], 'unit/ml)': [3024], 'resuspended': [3035], 'analyzed': [3042, 3077, 3610], '9%': [3044], 'gels.Cycloheximide': [3046], 'Treatment—To': [3047], 'evaluate': [3048], 'blocking': [3054], 'synthesis,': [3058], 'cultured': [3059, 3145, 3366, 3391, 3526], '24': [3062], 'treated': [3066], 'cycloheximide': [3068], '(100': [3069], 'μg/ml)': [3070], 'indicated': [3073, 3809], 'immunoblotting.Primary': [3079], 'Rat': [3080], 'Hippocampal': [3081], 'Neuronal': [3082], 'Cultures—Low': [3083], 'density': [3084], 'embryonic': [3086, 3204], 'rat': [3087, 3207, 4299], 'cultures': [3089, 3298], 'according': [3092], 'established': [3094, 3296], 'protocols': [3095], '(41Banker': [3096], 'Cowan': [3098], 'W.M.': [3099], 'Brain': [3100], '1977;': [3102], '126:': [3103], '397-425Crossref': [3104], '(947)': [3107], '42Lim': [3110], 'Antonucci': [3112], 'Scannevin': [3114], 'R.H.': [3115], '25:': [3120], '385-397Abstract': [3121], 'Briefly,': [3132, 3390], 'astrocyte': [3134, 3178, 3297, 3320], 'cerebral': [3139], 'hemispheres': [3140], 'neonatal': [3142], 'rats': [3143], 'days': [3148], '6-well': [3150, 3288], 'plates': [3153, 3291], 'minimum': [3155, 3228], 'horse': [3160, 3234], '0.6%': [3163], 'glucose': [3164, 3238], 'plating': [3167], 'day': [3172, 3205], 'before': [3173], 'dissection,': [3176], 'changed': [3181, 3311, 3359], 'maintenance': [3184], '(minimum': [3186], 'N2': [3190], 'supplements,': [3191], '0.1%': [3192, 3424, 3450], 'ovalbumin,': [3193], 'sodium': [3197, 3410], 'pyruvate)': [3198], 'conditioning.': [3200], 'Hippocampi': [3201], 'dissected': [3202], '18': [3206], 'embryos': [3208], 'dissociated': [3210], 'treatment': [3212], '0.25%': [3214], 'trypsin': [3215], 'min.': [3221], 'preparation': [3224], 'plated': [3226], '0.06%': [3237], '22-mm': [3240], 'square': [3241], '(72': [3243], 'cells/mm2)': [3244, 3252], '60-cm': [3246], '(177': [3251], 'coated': [3254], 'mg/ml': [3257, 3513], 'poly-l-lysine.': [3258], 'Neurons': [3259], 'CO2': [3268], 'attach': [3273], 'coverslips,': [3276], 'transferred,': [3281], 'inverted': [3282], 'wax': [3284], 'pedestals,': [3285], 'contained': [3293], 'feeder': [3301], 'layer.': [3302], 'dishes,': [3307], 'media': [3309, 3315, 3331], 'serum-free': [3314], 'conditioned': [3316], 'separate': [3319], 'culture.': [3321], 'After': [3322, 3494], '3': [3323, 3461, 4354], 'days,': [3324], 'cytosine': [3325], 'arabinoside': [3326], 'μm': [3334], 'final': [3335], 'concentration.': [3336], 'Cultures': [3337], 'atmosphere': [3346], '95%': [3348], 'air': [3349], 'One-half': [3353], 'weekly.Immunofluorescence': [3360], 'Staining': [3361], 'Cultured': [3363, 3523], 'Neurons—Staining': [3364], '(43Antonucci': [3373], 'Lim': [3375], 'Vassanelli': [3377], 'Neuroscience.': [3381], '69-81Crossref': [3384], '(97)': [3387], 'fixed': [3394], '3%': [3396, 3399], '(w/v)': [3397, 3436], 'paraformaldehyde,': [3398], 'sucrose': [3400], 'saline': [3403], '(PBS,': [3404], '0.15': [3405], 'm': [3406], 'phosphate,': [3411], '7.4)': [3413], 'min,': [3416], '(v/v)': [3425, 3508], 'X-100.': [3427], 'Nonspecific': [3428], 'binding': [3429, 4195], 'sites': [3430], 'blocked': [3432], 'Blotto-T': [3434, 3472], '(4%': [3435], 'non-fat': [3437], 'dry': [3438], 'milk': [3439], '20': [3441], '8.0,': [3445], 'X-100).': [3452], 'overnight.': [3464], 'three': [3469, 3495], 'remove': [3474], 'excess': [3475], 'followed': [3478], 'appropriate': [3483], '(diluted': [3486], '1:2000': [3488], 'Blotto-T)': [3490], 'washes': [3496], 'PBS-T,': [3498], 'slides': [3504], '90%': [3507], 'glycerol': [3509], 'p-phenylenediamine': [3514], '9.0.Biochemical': [3518], 'Analysis': [3519], 'Neurons—Hippocampal': [3524], "Locke's": [3535], '(154': [3537], '5.6': [3540], 'KCl,': [3542], '2.3': [3543], 'CaCl2,1mm': [3545], 'MgCl2,': [3546], 'glucose,': [3549], 'HEPES,': [3552], '7.4),': [3554], 'harvested,': [3555], '12,000': [3559], '30': [3563], 'pellets': [3569], 'extracted': [3571], 'adding': [3573], 'buffer,': [3577], 'size-fractionated': [3578], '7.5%': [3580], 'SDS-acrylamide': [3581], 'gels,': [3582], 'immunoblotted': [3584], '(K57/1).RESULTSKChIP': [3587], 'Leads': [3589], 'Changes': [3591, 4232], 'Intracellular': [3594], 'Trafficking': [3595], 'Kv4.2—To': [3597], 'begin': [3598], 'address': [3600], 'pattern': [3614, 3648], 'either': [3619, 4154], 'alone': [3621, 3694, 3849, 4155, 4161, 4242], 'plus': [3624], 'KChIP4a.': [3629], 'virtually': [3633], 'all': [3634], 'Kv4.2-expressing': [3637, 4006, 4032], 'had': [3640, 4143], 'robust': [3641, 3783], 'perinuclear': [3647, 3707, 4221], '(Fig.': [3654, 3671, 3711, 3820, 3993, 4139, 4176, 4187, 4222, 4260, 4285, 4328, 4353], '1A).': [3655, 3672], 'no': [3657, 3733, 3798], 'intact': [3663], 'anti-ectodomain': [3666], 'To': [3673], 'determine': [3674, 3954], 'whether': [3675, 3955], 'fact': [3683], 'associated': [3684, 3800], 'double-labeled': [3689], 'resident': [3699], 'ER': [3700, 3716, 3803], 'calnexin,': [3702], 'yielded': [3704, 3998], 'co-localizing': [3706], 'patterns': [3710], '1F).': [3712], 'Consistent': [3713], 'Golgi': [3726], 'apparatus': [3727], 'marker': [3728], 'Lens': [3729, 3817], 'culinaris': [3730, 3818], 'agglutinin': [3731, 3819], 'revealed': [3732], 'overlap': [3734], '(Supplemental': [3735, 3828], 'Fig.': [3736, 3829], '1).Co-expression': [3737], 'Kv4:KChIP': [3747], 'cDNA': [3748, 4019], 'ratio': [3749, 4020], '2:1': [3751], 'resulted': [3752], 'change': [3756], '(Figs.': [3763, 3788, 3867], '2).': [3766, 3791], 'now': [3769, 3781], 'extended': [3770], 'periphery': [3773], 'cell,': [3776], 'displayed': [3782], 'residual': [3793], 'longer': [3799], 'Golgi,': [3807], 'co-localization': [3812, 3825], '1G)': [3821], 'loss': [3823], 'calnexin': [3827], '1).': [3830], 'However,': [3831, 4262], 'co-transfected': [3833], 'did': [3838, 4125, 4371], 'respond': [3840], 'manner': [3843], 'resembled': [3845], 'lack': [3853, 3957, 4049, 4062, 4362], 'presence': [3860], 'ER-localized': [3863], '1E': [3868], '2H).Fig.': [3870], '2KChIPs': [3871], 'localizations': [3874], 'transiently': [3882], '(A),': [3886], '(B),': [3888], '(C),': [3890], '(D)': [3893], 'KChIP-specific': [3897, 3932], '(KChIP1,': [3899], 'K55/7;': [3900], 'K60/41;': [3902], 'K90A/16;': [3904], '1G2)': [3907], 'after': [3908], 'E–H,': [3911], 'EGFP-Kv4.2': [3916, 3936], '(E),': [3919], '(F),': [3921], '(G),': [3923], 'KChIP4': [3925, 3959], '(H)': [3926], 'relevant': [3931], '(right': [3934], 'panels);': [3935], 'shown': [3939], '(left': [3943], 'panels).': [3944], 'Scale': [3945], 'bars,': [3946], 'μm.View': [3948], 'Large': [3949], 'Figure': [3951], 'ViewerDownload': [3952], '(PPT)To': [3953], 'simply': [3965], 'relative': [3973], 'dose': [3978, 4137, 4305, 4385], 'dependence': [3979, 4306], 'examined': [3992], '1H).': [3994], 'Increased': [3995, 4330], 'dose-dependent': [4000], 'increase': [4001], 'fraction': [4004], 'expression,': [4011, 4368], 'initial': [4013], 'apparent': [4015, 4252], 'KChIP2:Kv4.2': [4018], '1:128': [4022], 'maximal': [4024], '1:8–1:4.': [4027], 'percentage': [4030], 'exhibited': [4035, 4169, 4183], 'reached': [4039], 'plateau': [4041], '≈60%.': [4043], 'quantitative': [4051], 'response': [4052], 'simple': [4061], '>95%': [4066], 'KChIP2.': [4074], 'It': [4075], 'should': [4076], 'be': [4077], 'noted': [4078], 'similar': [4081, 4292, 4327, 4359], 'ceiling': [4082], 'our': [4086], 'previous': [4087], 'Kvβ': [4090], 'subunit': [4091], 'Kv1.2': [4094], 'yield': [4127], 'any': [4128, 4136, 4384], 'increases': [4130], 'tested': [4138], '1H).Interestingly,': [4140], 'when': [4152, 4276], 'Kv4.2.': [4158], 'generally': [4168], 'diffuse': [4171], 'throughout': [4173], '2,': [4177], 'A–C),': [4178], 'KChIP3-expressing': [4180], 'additional': [4184], 'nuclear': [4185], '2C)': [4188], 'consistent': [4189], 'its': [4191, 4361], 'DNA': [4194], 'function': [4196], '(44Spreafico': [4197], 'Barski': [4199], 'Farina': [4201], 'Meyer': [4203], '17:': [4209], '1-16Crossref': [4210], '(57)': [4213], 'contrast,': [4217], '2D),': [4223], 'suggesting': [4224, 4344], 'association': [4226], 'ER.KChIPs': [4229], 'Induce': [4230], 'Profound': [4231], 'Characteristics': [4236], 'Kv4.2—COS-1': [4238], 'single': [4245], 'mass': [4253], '65': [4255, 4270], 'kDa': [4256], 'gels': [4259], '3).': [4261], 'two': [4263], 'populations': [4265], 'protein,': [4268], '70': [4272], 'kDa,': [4273], '-2,': [4282], '-3': [4284], '3,': [4286], 'A–C).': [4287], '70-kDa': [4289], 'form': [4290], 'M': [4295, 4316, 4375], 'r': [4296, 4317, 4376], 'brain': [4300], '(see': [4302], 'below).': [4303, 4357], 'induction': [4309], 'increased': [4315, 4340], 'values': [4318], 'upon': [4321], 'quite': [4326], '3E).': [4329], 'levels': [4333], 'turnover': [4351], 'rates': [4352], 'see': [4356], 'effect': [4364], 'teste': [4386]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2054792009', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 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