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156, 198, 350, 440, 835, 1201, 4520, 4553, 4585], 'underlying': [5, 199, 1163], 'store-mediated': [6, 56, 82, 102, 134, 148, 163, 200, 250, 276, 296, 328, 342, 357, 394, 881, 3259], 'Ca2+': [7, 46, 57, 61, 83, 103, 135, 149, 164, 201, 240, 251, 255, 277, 297, 329, 343, 358, 412, 649, 662, 666, 882, 939, 995, 1015, 1049, 1145, 1191, 1236, 1289, 1635, 1960, 2015, 2024, 2218, 2251, 2268, 2833, 2872, 2881, 2960, 3023, 3067, 3082, 3094, 3141, 3169, 3216, 4065, 4076, 4117, 4291, 4301, 4311, 4455, 4492, 4496, 4502, 4509, 4528, 4706], 'entry': [8, 58, 84, 150, 165, 202, 252, 278, 344, 359, 396, 415, 650, 667, 883, 996, 1016, 1050, 1192, 1237, 1290, 1961, 2219, 2834, 3011, 3024, 3083, 3142, 3217, 3261, 4066, 4077, 4452, 4503], 'has': [9, 203, 582, 806, 907, 1232, 1238, 2722, 3210, 3628, 4486, 4533, 4701], 'been': [10, 204, 583, 807, 875, 908, 1239, 2723, 3101, 3211, 3263, 3629, 4411, 4441], 'investigated': [11, 205], 'in': [12, 166, 206, 360, 885, 994, 1000, 1165, 1196, 1500, 1572, 1613, 1625, 1645, 1657, 1675, 1762, 1779, 1801, 1817, 1835, 1855, 1938, 1999, 2009, 2033, 2086, 2269, 2408, 2475, 2478, 2492, 2495, 2502, 2575, 2642, 2645, 2659, 2662, 2719, 2775, 2783, 2799, 2808, 2827, 2888, 2906, 2913, 2923, 2973, 2979, 2991, 2999, 3040, 3096, 3133, 3149, 3165, 3257, 3292, 3336, 3417, 3420, 3435, 3443, 3487, 3568, 3571, 3624, 3727, 3730, 3782, 3960, 4136, 4244, 4249, 4312, 4396, 4416, 4472, 4586, 4603, 4606, 4638, 4662, 4682], 'human': [13, 207, 406, 1997, 2044, 2162, 2300, 2762, 2814, 3889, 4049, 4258, 4587, 4604], 'platelets': [14, 167, 208, 361, 893, 1197, 1395, 1616, 1691, 1755, 1786, 1830, 1919, 1998, 2045, 2115, 2163, 2196, 2245, 2340, 2477, 2494, 2507, 2644, 2661, 2763, 2815, 2894, 3097, 3256, 3289, 3419, 3440, 3570, 3625, 3890, 4050, 4141, 4166, 4259, 4373, 4605, 4684, 4691], 'through': [15, 209, 913, 937], 'a': [16, 32, 70, 172, 210, 226, 264, 366, 470, 558, 591, 674, 802, 837, 850, 916, 922, 934, 990, 1007, 1020, 1132, 1257, 1262, 1296, 1547, 1719, 1867, 2006, 2030, 2051, 2087, 2449, 2503, 2616, 2668, 2706, 2776, 2828, 2907, 3046, 3293, 3390, 3436, 3444, 3541, 3894, 3961, 4061, 4392, 4467, 4491, 4495, 4512, 4542, 4550, 4591, 4607, 4639, 4702], 'combination': [17, 211], 'cytoskeletal': [19, 213, 4565], 'modifications.': [20, 214], 'Inhibition': [21, 215], 'actin': [23, 67, 128, 217, 261, 322, 869, 983, 1004, 1039, 1205, 1214, 1218, 1253, 1284, 2057, 2066, 2083, 2110, 2136, 2141, 2177, 2186, 2278, 2681, 2717, 2729, 3038, 3052, 3073, 3595, 3794, 3827, 3964, 4132, 4597, 4601, 4631], 'polymerization': [24, 218, 2058, 2137, 2279, 2677, 3228, 3591, 4133, 4602, 4632], 'by': [25, 43, 171, 219, 237, 365, 441, 474, 673, 809, 1017, 1034, 1075, 1216, 1227, 1241, 1321, 1453, 1489, 1664, 1789, 1833, 2138, 2220, 2275, 2838, 2916, 3014, 3025, 3190, 3230, 3631, 3657, 4068, 4078, 4179, 4274, 4318, 4388, 4443, 4521, 4633], 'cytochalasin': [26, 98, 220, 292, 397, 1272, 2346, 2513], 'D': [27, 221, 398, 1273, 1358, 2104, 2204, 2347, 2514, 3090, 3114, 3121, 3155, 3183, 3246, 3268, 3324, 3430, 3475, 3581, 3656, 3698, 3725, 3760, 4694], 'or': [28, 222, 555, 733, 1144, 2208, 2242, 2289, 2350, 2360, 2375, 2517, 2527, 2542, 2853, 3122, 3248, 3329, 3428, 3480, 3579, 4494, 4549, 4695], 'latrunculin': [29, 223, 1277, 1370, 2130, 2167, 2211, 2243, 2286, 2355, 2522, 3201, 3206, 3242, 3315, 3424, 3466, 3575, 4627, 4696], 'A': [30, 144, 224, 338, 727, 1361, 1371, 1380, 1959, 2039, 2168, 2212, 2291, 2356, 2371, 2523, 2538, 3107, 3207, 3243, 3958, 4059, 4072, 4130, 4146, 4171, 4270, 4284, 4322, 4325, 4332, 4380, 4421, 4437, 4485, 4697, 4708], 'had': [31, 225, 2105, 2866, 3100, 3262, 4410, 4440], 'biphasic': [33, 227, 4703], 'time-dependent': [34, 228, 2088, 4608], 'effect': [35, 229, 1031, 1234, 2107, 2183, 2868, 2876, 2968, 3110, 3164, 3757, 4298, 4329, 4489, 4613, 4704], 'on': [36, 230, 610, 849, 1135, 2108, 2184, 2292, 2869, 2877, 2969, 3093, 3251, 3761, 4116, 4131, 4299, 4333, 4540, 4614, 4705], 'Ca2+entry,': [37, 231], 'showing': [38, 232], 'an': [39, 107, 233, 301, 1836, 2132, 2247, 3728, 3786, 4389], 'initial': [40, 234, 2930, 2976], 'potentiation': [41, 235], 'followed': [42, 236, 4387], 'inhibition': [44, 100, 138, 238, 294, 332, 2092, 2276, 2909], 'entry.': [47, 104, 136, 241, 298, 330, 3068, 4707], 'Moreover,': [48, 242, 1271], 'addition': [49, 243, 1631, 1654, 1990, 2020, 2395, 2427, 2562, 2594, 3152, 3204, 3240, 3368, 3519, 3719, 4445], 'these': [51, 245, 1251, 2229, 3180, 4714], 'agents': [52, 246, 1280, 2230, 4715], 'after': [53, 91, 247, 285, 1193, 1291, 1629, 1652, 2093, 2425, 2592, 2804, 2846, 2936, 2983, 3098, 3129, 3208, 3366, 3517, 4367, 4413, 4438, 4569, 4624], 'induction': [54, 248], 'inhibited': [59, 145, 253, 339, 4173, 4271], 'influx': [62, 256, 560, 1636, 3095, 4532], 'mechanism.': [63, 257], 'Jasplakinolide,': [64, 258], 'which': [65, 116, 185, 259, 310, 379, 442, 614, 867, 938, 1305, 2059, 2675, 3258, 3589, 4191, 4522, 4629], 'reorganizes': [66, 260], 'filaments': [68, 262, 1005, 1219, 1254, 2067, 2682, 2730, 3039, 3596, 3965], 'into': [69, 263, 741, 1006, 1318], 'tight': [71, 265, 1008], 'cortical': [72, 266, 1038, 2716, 3051, 3793], 'layer': [73, 267, 1009], 'adjacent': [74, 268], 'to': [75, 122, 189, 269, 316, 383, 450, 617, 626, 654, 670, 877, 986, 1011, 1156, 1585, 1695, 1771, 1890, 1995, 2025, 2061, 2120, 2140, 2411, 2463, 2578, 2630, 2725, 2945, 3115, 3339, 3349, 3404, 3490, 3500, 3555, 3647, 3740, 3789, 3829, 4142, 4151, 4237, 4579, 4635], 'plasma': [77, 183, 271, 377, 388, 419, 1449, 1472], 'membrane,': [78, 184, 272, 378], 'prevented': [79, 97, 131, 273, 291, 325, 3754, 4599], 'activation': [80, 132, 146, 274, 326, 340, 914, 1189, 3065, 4474, 4500, 4570], 'but': [85, 151, 279, 345, 839, 4156, 4475], 'did': [86, 152, 280, 346, 3619, 4285, 4294, 4448], 'not': [87, 153, 281, 347, 3219, 3620, 4124, 4160, 4286, 4449, 4476], 'modify': [88, 282, 3622, 4450], 'this': [89, 155, 283, 349, 643, 862, 1200, 1230, 3147, 4414], 'process': [90, 284, 4514], 'its': [92, 286], 'activation.': [93, 287, 1292], 'In': [94, 288, 401, 859, 904, 977, 1150, 1983, 2225, 2794, 2863, 2955, 3751, 3950], 'addition,': [95, 289, 905, 2795, 3752], 'jasplakinolide': [96, 290, 400, 1887, 2365, 2532], 'D-induced': [99, 293], 'Calyculin': [105, 299, 1379, 4071], 'A,': [106, 300, 1278, 2131, 2287, 3316, 3425, 3467, 3576, 3770, 3893, 4190, 4628], 'inhibitor': [108, 302, 2055, 3897, 4595], 'protein': [110, 304, 3900], 'serine/threonine': [111, 305, 3895], 'phosphatases': [112, 306, 3901], '1': [113, 307, 1514, 1650, 1681, 1812, 2170, 2214, 2232, 2349, 2358, 2361, 2516, 2525, 2528, 2926, 3157, 3352, 3503, 3902, 4261, 4382, 4394, 4431], 'and': [114, 175, 308, 369, 460, 599, 602, 664, 789, 798, 845, 871, 924, 1028, 1048, 1198, 1268, 1276, 1302, 1347, 1359, 1369, 1427, 1445, 1461, 1465, 1498, 1518, 1526, 1563, 1566, 1582, 1689, 1853, 1880, 1928, 2040, 2222, 2298, 2422, 2430, 2455, 2589, 2597, 2622, 2678, 2727, 2842, 2994, 3060, 3091, 3244, 3309, 3363, 3371, 3395, 3460, 3514, 3522, 3546, 3592, 3723, 3804, 3817, 3903, 4091, 4105, 4252, 4480, 4560, 4568], '2': [115, 309, 1479, 1860, 2373, 2540, 2890, 3003, 3904, 4052, 4148], 'activates': [117, 311, 4530], 'translocation': [118, 312], 'existing': [120, 314], 'F-actin': [121, 315, 1685, 2294, 2432, 2445, 2473, 2490, 2599, 2612, 2640, 2657, 2781, 2800, 3186, 3227, 3253, 3373, 3386, 3415, 3524, 3537, 3566, 3666, 3732, 4154, 4177, 4616], 'cell': [124, 318, 403, 887, 2734, 3042], 'periphery': [125, 319, 3043], 'without': [126, 320, 1222, 2180, 2967, 3161, 3249, 4112, 4610], 'inducing': [127, 321], 'polymerization,': [129, 323, 4598], 'also': [130, 324], 'Finally,': [137, 331, 3642], 'vesicular': [140, 334, 872, 1136, 4194], 'transport': [141, 335, 1140, 4195, 4243, 4336, 4471], 'with': [142, 181, 336, 375, 642, 773, 1102, 1429, 1478, 1520, 1558, 1794, 1811, 1821, 1922, 1977, 2046, 2129, 2164, 2200, 2228, 2258, 2261, 2343, 2389, 2471, 2488, 2510, 2556, 2638, 2655, 2764, 2806, 2822, 2851, 2895, 3213, 3247, 3305, 3413, 3456, 3564, 3743, 3767, 3798, 3884, 3891, 3956, 4057, 4167, 4266, 4320, 4376, 4433, 4466, 4626, 4664, 4692, 4713], 'brefeldin': [143, 337, 1360, 4269, 4321, 4331, 4370, 4379, 4400, 4420, 4436, 4484], 'alter': [154, 348, 4287], 'once': [157, 351, 1235, 3626], 'initiated.': [158, 352], 'These': [159, 353, 1246, 3196, 4659], 'data': [160, 354, 1962], 'suggest': [161, 355, 1248], 'that': [162, 356, 604, 648, 665, 731, 783, 910, 1022, 1181, 1199, 1210, 1249, 1260, 1281, 1295, 2134, 2265, 3741, 3811, 3898, 4255, 4308, 4483, 4680], 'may': [168, 362, 608, 920, 1138, 1202, 1306], 'be': [169, 363, 618, 671, 878, 4365], 'mediated': [170, 364, 1226], 'reversible': [173, 367, 840, 925, 4338], 'trafficking': [174, 368, 852, 1137], 'coupling': [176, 370, 462, 465, 587, 776, 804, 980, 1025, 1047, 1225, 4552, 4584], 'endoplasmic': [179, 373, 390, 596], 'reticulum': [180, 374, 391, 597], 'shows': [186, 380, 3108], 'close': [187, 381, 985, 1263], 'parallels': [188, 382], 'events': [191, 385], 'mediating': [192, 386], 'secretion.': [193, 387, 1001], 'membrane': [389, 420, 928], 'inositol': [392], '1,4,5-trisphosphate': [393], 'calcium': [395, 559, 606, 3260], 'thapsigargin': [399, 1348, 4180], 'many': [402, 3951], 'types,': [404], 'including': [405, 892, 3953], 'platelets,': [407, 3954], 'depletion': [408, 746, 797, 1195, 1242, 4506], 'intracellular': [411, 2254, 2884, 4121, 4242, 4305, 4335, 4470, 4508], 'stores': [413, 447, 564, 663, 2255, 2272, 3173, 4122, 4315, 4510, 4529], 'induces': [414, 2676, 3590], 'Ca2+across': [417], '(PM)1': [421], '(1.Sage': [422], 'S.O.': [423, 542, 897, 1174, 1406], 'Reast': [424], 'R.': [425, 694], 'Rink': [426], 'T.J.': [427], 'Biochem.': [428, 507, 631, 1706, 3708, 3839, 4012, 4037], 'J.': [429, 486, 502, 506, 508, 525, 543, 632, 898, 965, 1175, 1407, 1598, 1701, 1737, 1906, 2693, 3607, 3681, 3860, 3934, 3995, 4010, 4026, 4038, 4202, 4214, 4219, 4342, 4349], '1990;': [430, 489, 4352], '265:': [431, 490], '675-680Crossref': [432], 'PubMed': [433, 495, 512, 534, 552, 573, 636, 686, 700, 722, 764, 829, 974, 1067, 1095, 1126, 1416, 1607, 1713, 1748, 1915, 2076, 2155, 2702, 2755, 3616, 3690, 3713, 3847, 3871, 3921, 3945, 3985, 4016, 4042, 4208, 4230, 4355, 4654, 4675], 'Scopus': [434, 513, 574, 637, 687, 701, 723, 765, 830, 1068, 1096, 1127, 1608, 1714, 1749, 2077, 2156, 2756, 3714, 3848, 3872, 3922, 3946, 3986, 4017, 4043, 4209, 4231, 4356, 4655, 4676], '(116)': [435], 'Google': [436, 496, 515, 535, 553, 576, 639, 689, 703, 725, 767, 832, 957, 975, 1070, 1098, 1129, 1417, 1610, 1716, 1751, 1916, 2079, 2158, 2703, 2758, 3617, 3691, 3716, 3850, 3874, 3924, 3948, 3988, 4019, 4045, 4211, 4233, 4358, 4657, 4678], 'Scholar).': [437, 640, 726, 768, 833, 903, 976, 1071, 1418, 1611, 1752, 2159, 2759, 3717, 3875, 3949, 4046, 4658], 'However,': [438, 4163, 4518], 'filling': [444, 4524], 'state': [445, 4525], 'is': [448, 615, 651, 668, 771, 781, 792, 1032, 1100, 1310, 2705, 3076, 3693, 3822, 4337, 4464, 4511, 4685], 'communicated': [449], 'PM': [452, 601, 628, 743, 791, 847, 988, 1013, 1320, 2738, 3062, 3831, 3886, 3968, 4559], 'remains': [453], 'unclear.': [454, 4535], 'Hypotheses': [455], 'have': [456, 874, 1168, 3809, 4296], 'considered': [457], 'both': [458, 3721], 'indirect': [459], 'direct': [461, 586, 1297, 4551], 'mechanisms.': [463], 'Indirect': [464], 'assumes': [466], 'existence': [468], 'diffusible': [471, 675, 4543], 'messenger': [472, 580, 4544], 'generated': [473], 'storage': [476], 'organelles': [477], 'such': [478, 4531], 'as': [479, 997, 1019, 1256, 1398, 1639, 1894, 1936, 2382, 2436, 2448, 2458, 2549, 2603, 2615, 2625, 3045, 3221, 3223, 3296, 3334, 3377, 3389, 3398, 3447, 3485, 3528, 3540, 3549, 4406, 4490, 4578], 'cyclic': [480], 'GMP': [481], '(2.Pandol': [482], 'S.J.': [483], 'Schoeffield-Payne': [484], 'M.S.': [485], 'Biol.': [487, 526, 544, 966, 1408, 1599, 1738, 1907, 2694, 3608, 3682, 3861, 3935, 4204, 4220, 4351], 'Chem.': [488, 527, 545, 967, 1409, 1600, 1739, 1908, 2695, 3609, 3683, 3862, 3936, 4221], '12846-12853Abstract': [491], 'Full': [492, 531, 549, 717, 719, 759, 761, 824, 826, 971, 1062, 1064, 1090, 1092, 1121, 1123, 1413, 1604, 1743, 1745, 1912, 2699, 2750, 2752, 3613, 3687, 3844, 3866, 3868, 3916, 3918, 3940, 3942, 3980, 3982, 4225, 4227], 'Text': [493, 532, 550, 718, 720, 760, 762, 825, 827, 972, 1063, 1065, 1091, 1093, 1122, 1124, 1414, 1605, 1744, 1746, 1913, 2700, 2751, 2753, 3614, 3688, 3845, 3867, 3869, 3917, 3919, 3941, 3943, 3981, 3983, 4226, 4228], 'PDF': [494, 533, 551, 721, 763, 828, 973, 1066, 1094, 1125, 1415, 1606, 1747, 1914, 2701, 2754, 3615, 3689, 3846, 3870, 3920, 3944, 3984, 4229], 'Scholar),': [497, 516, 554, 1917, 2080, 2704, 3618, 4234, 4359, 4679], 'cytochrome': [498], 'P-450': [499], 'metabolites': [500], '(3.Alvarez': [501], 'Montero': [503], 'M.': [504, 710, 752, 1114, 1595, 3855, 3929, 3993, 3997, 4001, 4009, 4024], 'Garcia-Sancho': [505], '1991;': [509, 528], '274:': [510, 3864, 3938], '193-197Crossref': [511], '(144)': [514], 'tyrosine': [517], 'kinases': [518], '(4.Vostal': [519], 'J.G.': [520, 4340], 'Jackson': [521], 'W.L.': [522], 'Shulman': [523], 'N.R.': [524, 2146, 4645], '266:': [529], '16911-16916Abstract': [530], 'Scholar,': [536, 690, 704, 958, 3851, 3925, 3989, 4020, 4212], '5.Sargeant': [537], 'P.': [538, 1402], 'Farndale': [539, 1403], 'R.W.': [540, 1404], 'Sage': [541, 896, 1173, 1405], '1993;': [546, 570, 954, 1410], '268:': [547, 1411], '18151-18156Abstract': [548, 1412], 'release': [556, 2013, 2249, 2879, 3167, 4118, 4302], 'factor': [561], 'from': [562, 623, 1329, 1351, 1363, 1373, 1382, 1423, 1533, 2016, 2252, 2672, 2882, 2941, 3170, 4119, 4303, 4546], 'depleted': [563], '(6.Radriamanpita': [565], 'C.': [566, 1703], 'Tsien': [567, 711, 753, 1115, 1596], 'R.Y.': [568, 712, 754, 1116, 1597], 'Nature.': [569, 2072, 4671], '364:': [571], '809-813Crossref': [572], '(789)': [575], 'Scholar);': [577], 'however,': [578], 'no': [579, 1233, 2106, 2796, 2867, 4487], 'molecule': [581, 676], 'identified.': [584], 'Alternatively,': [585], '(conformational': [588], 'coupling)': [589], 'proposes': [590], 'physical': [592, 838, 851, 1258, 4555], 'interaction': [593, 841, 926, 1264, 1298, 3057, 4556], 'between': [594, 786, 842, 927, 1026, 1265, 1299, 3058, 3801, 4557], '(ER)': [598], 'considers': [603], 'some': [605, 645], 'sensitivity': [607], 'reside': [609], 'InsP3': [612, 657], 'receptor,': [613], 'thought': [616], 'responsible': [619], 'for': [620, 880, 1187, 1455, 1482, 1495, 1649, 1673, 1782, 1791, 1808, 1847, 1942, 1957, 2118, 2169, 2205, 2213, 2231, 2348, 2357, 2366, 2372, 2378, 2403, 2515, 2524, 2533, 2539, 2545, 2570, 2709, 2768, 2816, 2848, 2899, 3033, 3064, 3078, 3156, 3649, 3665, 3824, 4051, 4147, 4260, 4381, 4391, 4407, 4430, 4469, 4698], 'transmitting': [621], 'information': [622], 'ER': [625, 788, 844, 855, 1027, 1143, 1267, 1301, 3059, 3803, 4548], '(7.Berridge': [629], 'B.J.': [630], '1995;': [633, 4013, 4039], '312:': [634], '1-11Crossref': [635], '(1050)': [638], 'Consistent': [641], 'model,': [644, 981], 'studies': [646, 3808, 4666], 'indicate': [647, 4254], 'closely': [652], 'localized': [653], 'sites': [655], 'where': [656, 1963, 3037], 'evokes': [658], 'emptying': [659], 'unlikely': [669], 'activated': [672, 1240, 1690, 1761, 3630, 3762, 4442], '(8.Petersen': [677], 'C.C.': [678], 'Berridge': [679], 'M.J.': [680], 'Pflügers': [681], 'Arch.': [682, 3707], '1996;': [683, 1710, 1740], '432:': [684], '286-292Crossref': [685], '(59)': [688], '9.Pareck': [691], 'A.B.': [692], 'Penner': [693], 'Physiol.': [695, 899, 1176], 'Rev.': [696], '1997;': [697, 3841], '77:': [698], '901-930Crossref': [699], '(1294)': [702], '10.Yao': [705], 'Y.': [706, 748, 1110, 2148, 4005, 4022, 4647], 'Ferrer-Montiel': [707, 749, 1111], 'A.V.': [708, 750, 1112], 'Montal': [709, 751, 1113], 'Cell.': [713, 755, 820, 1058, 1086, 1117, 2746, 3912, 3976, 4011], '1999;': [714, 756, 821, 900, 1059, 1087, 1118, 1177, 2747, 3863, 3913, 3937, 3977], '98:': [715, 757, 822, 1060, 1088, 1119, 2748, 3914, 3978], '475-485Abstract': [716, 758, 1120], '(232)': [724, 766, 1128], 'different': [728, 886, 4564, 4699], 'model': [729, 777, 805, 1073, 1133], 'suggests': [730, 1294], 'Ca2+channels': [732], 'membrane-': [734], 'bound': [735], 'activator': [736], 'molecules': [737], 'are': [738, 1185, 2443, 2456, 2610, 2623, 3384, 3396, 3535, 3547, 4134, 4538], 'exocytotically': [739], 'incorporated': [740], 'upon': [744, 2256], 'store': [745, 796, 1194], '(10.Yao': [747, 1109], 'This': [769, 834, 1030, 1293, 4462], 'hypothesis': [770, 1104], 'compatible': [772, 1101, 4465], 'conformational': [775], 'only': [778], 'if': [779], 'it': [780, 906, 998, 4295], 'assumed': [782], 'link': [785], 'mechanically': [793], 'weak': [794], 'before': [795, 2393, 2419, 2560, 2586, 3360, 3511, 4567], 'strong': [799], 'afterward.': [800], 'Recently,': [801], 'secretion-like': [803, 979], 'proposed': [808], 'Patterson': [810, 1076], 'et': [811, 1077, 1107, 1590], 'al.': [812, 1078, 1108, 1591], '(11.Patterson': [813, 1051, 1079, 2739, 3905, 3969], 'R.L.': [814, 1052, 1080, 2740, 3906, 3970], 'van': [815, 1053, 1081, 2741, 3907, 3971], 'Rossum': [816, 1054, 1082, 2742, 3908, 3972], 'D.B.': [817, 1055, 1083, 2743, 3909, 3973], 'Gill': [818, 963, 1056, 1084, 2744, 3910, 3974], 'D.L.': [819, 944, 964, 1057, 1085, 2745, 3911, 3975], '487-499Abstract': [823, 1061, 1089, 2749, 3915, 3979], '(387)': [831, 1069, 1097, 2757, 3923, 3987], 'involves': [836], 'based': [848, 1134], 'toward': [856, 1147], 'PM.': [858, 1029, 1149, 1270, 3806], 'support': [860, 1139], 'hypothesis,': [863], 'small': [864, 917, 1182], 'GTP-binding': [865, 918, 1183], 'proteins,': [866], 'modulate': [868], 'reorganization': [870], 'trafficking,': [873], 'shown': [876, 909, 1169, 2724, 2887, 3132, 3810, 4135, 4248], 'important': [879], '(SMCE)': [884], 'types': [888], '(e.g.': [889], '12,': [890], '13)': [891], '(14.Rosado': [894, 1171], 'J.A.': [895, 1172, 4218], '520:': [901, 1178], '20-21Google': [902, 1179], 'GTP,': [911], 'possibly': [912], 'protein,': [919], 'activate': [921], 'rapid': [923], 'surfaces': [929], 'involving': [930, 4554], 'formation': [932, 2085, 2179, 3188], 'prefusion': [935], 'pore': [936], 'ions': [940], 'can': [941, 1287], 'flow': [942], '(15.Gill': [943], 'Ghosh': [945, 961], 'T.K.': [946, 962], 'Short': [947], 'A.D.': [948], 'Waldron': [949], 'R.T.': [950], 'Handb.': [951], 'Exp.': [952], 'Pharmacol.': [953], '108:': [955], '625-649Crossref': [956], '16.Rys-Sikora': [959], 'K.E.': [960], '1994;': [968, 1909, 2696, 3610, 3684], '269:': [969, 1910, 2697, 3611, 3685, 3711], '31607-31613Abstract': [970], 'cytoskeleton': [984, 1215, 2718, 3053, 3781, 3795], 'plays': [989], 'key': [991], 'regulatory': [992], 'role': [993, 2713, 4468], 'does': [999], 'Redistribution': [1002], 'subjacent': [1010], 'prevents': [1014, 1220, 1261, 2081], 'acting': [1018], 'barrier': [1021, 1259, 3047], 'blocks': [1023], 'reversed': [1033, 3184], 'disassembly': [1035], 'layer,': [1040], 'thus': [1041], 'providing': [1042], 'reestablishment': [1044], 'suggested': [1074], 'Scholar)': [1099, 1130, 1180, 1717, 3692], 'Yao': [1106], 'because': [1131, 3659], 'channels': [1146, 1317], 'present': [1152], 'study': [1153, 3775, 4238], 'we': [1154, 3008, 3084, 3784, 3887, 4360], 'sought': [1155], 'expand': [1157], 'our': [1158, 4573], 'understanding': [1159], 'mechanisms': [1162], 'SMCE': [1164, 1221, 2037, 2236, 2826, 3099, 3160, 3209, 3627, 3763, 3783, 4363, 4409, 4439, 4479], 'platelets.': [1166, 3117, 4588], 'We': [1167, 1207], 'previously': [1170, 1400, 1720], 'proteins': [1184, 3821, 3883], 'required': [1186, 3077, 3823], 'involve': [1203], 'cytoskeleton.': [1206], 'report': [1208], 'here': [1209], 'modification': [1211, 1231], 'stabilizing': [1217], 'affecting': [1223], 'chemical': [1224], 'InsP3;': [1228], 'however': [1229], 'stores.': [1245, 2018, 2885], 'results': [1247, 2126, 3197, 3959, 4247, 4403, 4574], 'under': [1250, 2438, 2605, 3298, 3379, 3449, 3530], 'conditions': [1252, 3181], 'act': [1255, 3044], '(Cyt': [1274], 'D)': [1275], 'two': [1279], 'disrupt': [1282], 'filament': [1285, 2084, 2111, 2178, 2187, 3074, 3187], 'network,': [1286], 'reverse': [1288], 'PM,': [1304], 'need': [1307], 'mechanical': [1308], 'support,': [1309], 'more': [1311], 'likely': [1312], 'than': [1313, 3695], 'incorporation': [1315], 'vesicle': [1322], 'fusion.': [1323], 'Fura-2': [1324], 'acetoxymethyl': [1325], 'ester': [1326], '(fura-2/AM)': [1327], 'was': [1328, 1381, 1421, 1450, 1473, 1531, 1617, 1637, 1692, 1864, 1882, 1930, 1949, 1967, 1981, 2273, 2434, 2601, 2802, 2835, 2938, 2966, 2986, 3125, 3143, 3332, 3347, 3375, 3483, 3498, 3526, 4159, 4235, 4316], 'Texas': [1330], 'Fluorescence': [1331, 1530], '(Austin,': [1332], 'TX).': [1333], 'Apyrase': [1334], '(grade': [1335], 'V),': [1336], 'aspirin,': [1337], 'bovine': [1338, 1523, 1824], 'serum': [1339, 1524, 1825], 'albumin,': [1340], 'paraformaldehyde,': [1341], 'Nonidet': [1342, 1797], 'P-40,': [1343], 'fluorescein': [1344, 1814, 1925], 'isothiocyanate-labeled': [1345, 1815, 1926], 'phalloidin': [1346, 1816, 1895, 1937], '(TG)': [1349], 'were': [1350, 1362, 1372, 1390, 1396, 1469, 1486, 1574, 1760, 1769, 1787, 1805, 1831, 1875, 1920, 2127, 2341, 2386, 2415, 2508, 2553, 2582, 3198, 3290, 3302, 3356, 3441, 3453, 3507, 3644, 4374, 4622], 'Sigma': [1352], '(Poole,': [1353], 'Dorset,': [1354], 'U.': [1355, 1366, 1385, 1556, 1845], 'K.).': [1356, 1367, 1386], 'Cyt': [1357, 2049, 2103, 2203, 2240, 2284, 3089, 3113, 3120, 3154, 3182, 3245, 3319, 3323, 3426, 3429, 3470, 3474, 3577, 3580, 3655, 3697, 3724, 3759, 4589, 4693], 'Calbiochem': [1364], '(Nottingham,': [1365, 1384], 'Jasplakinolide': [1368], 'Molecular': [1374], 'Probes': [1375], '(Leiden,': [1376], 'Netherlands).': [1378], 'Alexis': [1383], 'All': [1387], 'other': [1388, 2101, 3586], 'reagents': [1389], 'analytical': [1392], 'grade.': [1393], 'Fura-2-loaded': [1394], 'prepared': [1397, 1452], 'described': [1399, 2407, 2437, 2574, 2604, 3297, 3335, 3378, 3448, 3486, 3529], '(5.Sargeant': [1401], 'Briefly,': [1419, 1753], 'blood': [1420], 'obtained': [1422, 2128], 'healthy': [1424], 'drug-free': [1425], 'volunteers': [1426], 'mixed': [1428], 'one-sixth': [1430], 'volume': [1431], 'acid/citrate': [1433], 'dextrose': [1434], 'anticoagulant': [1435], 'containing': [1436, 1503, 2925], '(in': [1437, 1504], 'mm)': [1438, 1505], '85': [1439], 'sodium': [1440], 'citrate,': [1441], '78': [1442], 'citric': [1443], 'acid': [1444], '111': [1446], 'd-glucose.': [1447], 'Platelet-rich': [1448, 1471], 'then': [1451, 1487, 1806, 2387, 2554, 3303, 3454], 'centrifugation': [1454, 1490, 1834], '5': [1456, 1512, 2417, 2584, 2852, 3358, 3509, 4457], 'min': [1457, 1497, 1628, 1651, 1793, 1810, 2095, 2122, 2207, 2233, 2359, 2526, 2770, 2818, 2850, 2901, 3128, 3311, 3462, 4053, 4149], 'at': [1458, 1475, 1491, 1543, 1568, 1850, 1877, 1883, 1932, 2002, 2172, 2197, 2732, 2771, 2819, 2902, 3146, 3966, 4054, 4098, 4263, 4384], '700': [1459], '×g': [1460, 1852], '100': [1462, 2369, 2536, 4143, 4168, 4267, 4377, 4434], 'μm': [1463, 1480, 1813, 1924, 2023, 2048, 2166, 2202, 2210, 2345, 2354, 2364, 2398, 2512, 2521, 2531, 2565, 2766, 2855, 2897, 3119, 3314, 3318, 3322, 3327, 3465, 3469, 3473, 3478, 4268, 4378, 4435], 'aspirin': [1464], '40': [1466, 1527, 2094, 2121, 2206, 2351, 2518], 'μg/ml': [1467, 1528], 'apyrase': [1468], 'added.': [1470], 'incubated': [1474, 1807, 1921, 2342, 2509], '37': [1476, 1544, 2003, 2173, 2198, 2772, 2820, 2903, 4055, 4264, 4385], '°C': [1477, 1545, 2004, 2174, 2199, 2773, 2821, 2904, 4056, 4265, 4386], 'fura-2/AM': [1481], '45': [1483], 'min.': [1484, 1784], 'Cells': [1485, 2385, 2552, 3301, 3452], 'collected': [1488, 1832], '350': [1492], '×': [1493, 1757, 1861], 'g': [1494], '20': [1496], 'resuspended': [1499, 1854], 'HEPES-buffered': [1501, 1763], 'saline': [1502, 1781, 1819], '145': [1506], 'NaCl,': [1507], '10': [1508, 1510, 1783, 1792, 1923, 2047, 2201, 2344, 2363, 2511, 2530, 2765, 2854, 2896, 3118, 3317, 3321, 3326, 3468, 3472, 3477], 'HEPES,': [1509], 'd-glucose,': [1511], 'KCl,': [1513], 'MgSO4,': [1515], 'pH': [1516], '7.45,': [1517], 'supplemented': [1519, 1820], '0.1%': [1521], '(w/v)': [1522, 1777, 1823], 'albumin': [1525], 'apyrase.': [1529], 'recorded': [1532], '1.5-ml': [1534], 'aliquots': [1535], 'magnetically': [1537], 'stirred': [1538, 2000], 'platelet': [1539, 1767], 'suspension': [1540, 1768], '(108': [1541], 'cells/ml)': [1542, 1759], 'using': [1546, 1576, 1619, 1866, 1951, 3103, 3200], 'Cairn': [1548], 'Research': [1549, 1552], 'Spectrophotometer': [1550], '(Cairn': [1551], 'Ltd.,': [1553], 'Sittingbourne,': [1554], 'Kent,': [1555], 'K.)': [1557, 1846], 'excitation': [1559], 'wavelengths': [1560], '340': [1562], '380': [1564], 'nm': [1565, 1993, 2391, 2558, 2949, 2990, 2998, 3307, 3458, 4144, 4169], 'emission': [1567, 1881], '500': [1569], 'nm.': [1570, 1885], 'Changes': [1571], '[Ca2+]i': [1573, 1646, 2034, 2914, 2932, 2980], 'monitored': [1575], 'fura-2': [1578], '340/380': [1579], 'fluorescence': [1580, 1869], 'ratio': [1581], 'calibrated': [1583], 'according': [1584, 1694], 'method': [1587], 'Grynkiewicz': [1589], '(17.Grynkiewicz': [1592], 'G.': [1593], 'Poenie': [1594], '1985;': [1601], '260:': [1602], '3440-3450Abstract': [1603], '(80)': [1609, 3715], 'Ca2+influx': [1612], 'TG-induced': [1614, 2176, 4300, 4600], 'store-depleted': [1615, 3116], 'estimated': [1618], 'integral': [1621, 1641, 1668], 'rise': [1624, 1644, 2972], '[Ca2+]ifor': [1626], '2.5': [1627], 'CaCl2.': [1633], 'Thrombin-evoked': [1634], 'measured': [1638, 1865], 'above': [1647, 2934, 2981], 'basal': [1648, 2453, 2620, 2935, 2982, 3394, 3545, 4615], 'thrombin': [1656, 2920, 3015], 'presence': [1659], 'external': [1661, 1679, 2027, 2959], 'Ca2+,': [1662, 1988, 2429, 2596, 3370, 3521], 'corrected': [1663], 'subtraction': [1665], 'over': [1669], 'same': [1671, 1892, 1934, 2380, 2547], 'period': [1672, 2381, 2548, 4415], 'stimulation': [1674, 2257, 2805, 2985], 'absence': [1677, 1985, 2480, 2497, 2647, 2664, 2957, 3422, 3573, 4398, 4418], 'Ca2+(with': [1680], 'mm': [1682, 2927, 2962], 'EGTA).': [1683], 'content': [1686, 2112, 2188, 2295, 2433, 2446, 2454, 2474, 2491, 2600, 2613, 2621, 2641, 2658, 2782, 2801, 3254, 3374, 3387, 3416, 3525, 3538, 3567, 3733, 4617], 'resting': [1688, 2476, 2643, 2870, 4289, 4683], 'determined': [1693, 2435, 2602, 3376, 3527], 'modifications': [1697, 4566], '(18.Molony': [1698], 'L.': [1699, 4199], 'Ng-Sikorski': [1700], 'Hellberg': [1702], 'Andersson': [1704], 'T.': [1705, 1728, 4007, 4028, 4030], 'Biophys.': [1707, 3709], 'Res.': [1708], 'Commun.': [1709], '223:': [1711], '612-617Crossref': [1712], '(13)': [1715], 'published': [1721], 'procedure': [1722], '(19.Hartwig': [1723], 'J.H.': [1724], 'Kung': [1725], 'S.': [1726, 3833, 3835, 3837, 3857, 3931, 4216], 'Kovacsovics': [1727], 'Janmey': [1729], 'P.A.': [1730], 'Cantley': [1731], 'L.C.': [1732], 'Stossel': [1733], 'T.P.': [1734], 'Toker': [1735], 'A.': [1736, 2150, 3202, 3853, 3927, 4371, 4401, 4649], '271:': [1741], '32986-32993Abstract': [1742], '(120)': [1750], 'washed': [1754], '(2': [1756], '108': [1758], 'saline.': [1764, 1803, 1857], 'Samples': [1765, 1874, 2414, 2581, 3355, 3506], 'transferred': [1770], '200': [1772, 1992, 2390, 2557, 3306, 3457], 'μl': [1773], 'ice-cold': [1775], '3%': [1776], 'formaldehyde': [1778], 'phosphate-buffered': [1780, 1802, 1818, 1856], 'Fixed': [1785], 'permeabilized': [1788], 'incubation': [1790, 1828, 4390], '0.025%': [1795], '(v/v)': [1796], 'P-40': [1798], 'detergent': [1799], 'dissolved': [1800], 'Platelets': [1804], '30': [1809, 2367, 2423, 2534, 2590, 2769, 2817, 2849, 2900, 3364, 3515], '0.5%': [1822], 'albumin.': [1826], 'After': [1827], 'MSE': [1837], 'Micro-Centaur': [1838], 'Centrifuge': [1839], '(MSE': [1840], 'Scientific': [1841], 'Instruments,': [1842], 'Crawley,': [1843], 'Sussex,': [1844], '90': [1848], 's': [1849, 2418, 2424, 2585, 2591, 3359, 3365, 3510, 3516], '3,000': [1851], 'Staining': [1858], '107': [1862], 'cells/ml': [1863], 'Perkin-Elmer': [1868], 'spectrophotometer': [1870], '(Perkin-Elmer,': [1871], 'Norwalk,': [1872], 'CT).': [1873], 'excited': [1876], '496': [1878], 'nm,': [1879, 4107], '516': [1884], 'Because': [1886, 4327], '(JP)': [1888], 'binds': [1889, 2060], 'site': [1893], '(20.Bubb': [1896, 2683, 3597, 3671], 'M.R.': [1897, 2684, 3598, 3672], 'Senderowicz': [1898, 2685, 3599, 3673], 'A.M.J.': [1899, 2686, 3600, 3674], 'Sausville': [1900, 2687, 3601, 3675], 'E.A.': [1901, 2688, 3602, 3676], 'Duncan': [1902, 2689, 3603, 3677], 'K.L.K.': [1903, 2690, 3604, 3678], 'Korn': [1904, 2691, 3605, 3679], 'E.D.': [1905, 2692, 3606, 3680], '14869-14871Abstract': [1911, 2698, 3612, 3686], 'fixed': [1918], 'phalloidin,': [1927], 'JP': [1929, 1943, 2721, 2767, 2823, 2865, 2898, 2965, 3019, 3092, 3250, 3658, 3664, 3722, 3744, 3753], 'added': [1931, 3126, 3333, 3348, 3484, 3499], 'time': [1935], 'control': [1940, 2992], 'samples': [1941], 'experiments.': [1944], 'Analysis': [1945], 'statistical': [1947], 'significance': [1948], 'performed': [1950], "Student's": [1952, 1964], 'unpaired': [1953], 't': [1954, 3137], 'test': [1955, 1966, 3648], 'except': [1956], 'calyculin': [1958, 2290, 3892, 3957, 4058, 4129, 4145, 4170], 'pairedt': [1965], 'used.': [1968, 1982], 'For': [1969], 'multiple': [1970], 'comparison,': [1971], 'one-way': [1972], 'analysis': [1973], 'variance': [1975], 'combined': [1976], 'Dunnett': [1979], 'tests': [1980], 'extracellular': [1987, 4454], 'TG': [1994, 2259, 2392, 2421, 2559, 2588, 2807, 3191, 3214, 3231, 3362, 3513, 3633, 4069, 4447], 'fura-2-loaded': [1996], 'cuvettes': [2001], 'evoked': [2005, 2915], 'prolonged': [2007], 'elevation': [2008, 2912, 2933, 2978], '[Ca2+]ibecause': [2010], 'internal': [2017, 2271, 3172, 4314], 'Subsequent': [2019, 3151], '300': [2022, 2397, 2564, 3345, 3496, 4106], 'medium': [2028, 2924, 3295, 3351, 3446, 3502], 'induced': [2029, 3229, 4067, 4178], 'sustained': [2031], 'increase': [2032, 2798, 3729, 4152, 4175], 'indicative': [2035], '(Fig.1,': [2038], 'D).': [2041], 'Pretreatment': [2042, 2812], 'D,': [2050, 2285, 2891, 3320, 3427, 3471, 3578, 4590], 'widely': [2052, 4592], 'utilized': [2053], 'membrane-permeant': [2054, 4594], 'barbed': [2063], 'end': [2064], '(26.Fox': [2068, 4667], 'J.E.B.': [2069, 4668], 'Phillips': [2070, 4669], 'D.R.': [2071, 4670], '1981;': [2073, 4672], '292:': [2074, 4673], '650-652Crossref': [2075, 4674], '(147)': [2078, 4677], 'TG-evoked': [2082, 2217, 2235, 2825, 2878, 3166], 'manner,': [2089], 'reaching': [2090], 'complete': [2091], 'treatment': [2097, 2847, 2892, 3955, 4256, 4625, 4689], '(TableI).': [2098, 2811], 'On': [2099, 3584], 'hand,': [2102, 3587], 'unstimulated': [2114, 2190, 2297, 2784], 'when': [2116], 'treated': [2117, 2388, 2555, 3888], 'up': [2119], '(Table': [2123, 2192, 3232, 3734, 3746, 4181, 4618], 'I).': [2124, 2193, 2793, 4619], 'Similar': [2125, 4620], 'agent': [2133], 'inhibits': [2135, 3899, 4193, 4630], 'binding': [2139, 3661, 4634], 'monomers': [2142], '(27.Spector': [2143, 4642], 'I.': [2144, 4138, 4643], 'Shochet': [2145, 4644], 'Kashman': [2147, 4646], 'Groweiss': [2149, 4648], 'Science.': [2151, 4650], '1983;': [2152, 4651], '219:': [2153, 4652], '493-495Crossref': [2154, 4653], '(615)': [2157, 4656], 'Treatment': [2160, 2194, 2760, 4047, 4427], '3': [2165, 2209, 2353, 2520, 3106, 3127, 3135, 3139, 3175, 3310, 3313, 3461, 3464, 3769], 'h': [2171, 2215, 3158, 3353, 3504, 4262, 4383, 4395, 4432], 'abolished': [2175, 3215], 'having': [2181, 3162, 4113, 4611], 'any': [2182, 2875, 3163, 4297, 4612], 'cells': [2191, 2785, 2810, 2993, 3001, 4429], 'reduced': [2216, 2836, 2939, 3021, 4074], '50': [2221, 3701], '65%,': [2223], 'respectively.': [2224], 'contrast,': [2226, 2864], 'preincubation': [2227, 4319, 4710], 'increased': [2234], '(Fig.': [2237, 2280, 2831, 3002, 3174, 4323, 4422, 4456], '1,': [2238], 'A–F).': [2239], 'D-': [2241], 'A-treated': [2244], 'showed': [2246], 'identical': [2248], 'compared': [2260, 2470, 2487, 2637, 2654, 3412, 3563], 'untreated': [2262], 'cells,': [2263, 3952], 'indicating': [2264, 4307], 'accumulation': [2266, 4309], 'unaffected': [2274, 4317], '1,A-F).Table': [2281], 'IEffects': [2282], 'JP,': [2288, 2667, 2856, 3328, 3479, 3588], 'TG-stimulated': [2299, 4272], 'plateletsStimulatory': [2301], 'agentControlCyt': [2302], 'DLatrunculin': [2303], 'AJPCalyculin': [2304], 'A1': [2305], 'min40': [2306], 'min1': [2307, 2308], 'h%': [2309], 'basalNone100.0': [2311, 3272], '±': [2312, 2314, 2316, 2318, 2320, 2322, 2324, 2326, 2328, 2330, 2332, 2334, 2336, 2338, 2840, 2844, 2943, 2947, 2988, 2996, 3027, 3273, 3275, 3277, 3279, 3281, 3283, 3285, 3287, 3400, 3551, 4080, 4083, 4086, 4089, 4093, 4276], '0.0100.4': [2313], '3.0100.1': [2315], '3.2100.5': [2317], '2.0100.4': [2319], '2.0179.7': [2321], '3.3*107.4': [2323], '4.1TG133.7': [2325], '4.6128.3': [2327], '3.898.9': [2329], '4.1**129.9': [2331], '4.099.7': [2333], '2.3**177.5': [2335], '4.4**109.8': [2337], '5.9**Human': [2339], 'min,': [2352, 2368, 2374, 2519, 2535, 2541], 'h,': [2362, 2529], 'nmcalyculin': [2370, 2537], 'vehicles': [2377, 2544], 'controls.': [2384, 2551], 'CaCl2,': [2399, 2566], 'following': [2400, 2567, 4504], 'protocol': [2402, 2569], 'measurement': [2404, 2571], '[Ca2+],': [2406, 2573], 'legend': [2410, 2577, 3338, 3489], 'Fig.': [2412, 2579, 2889, 3105, 3134, 3340, 3491, 3768, 4250], '1.': [2413, 2580], 'removed': [2416, 2583, 3357, 3508], 'adding': [2420, 2587, 3112, 3361, 3512, 3632], '"Experimental': [2439, 2606, 3017, 3299, 3380, 3450, 3531], 'Procedures."': [2440, 2607, 3300, 3381, 3451, 3532], 'Values': [2441, 2608, 3382, 3533], 'given': [2442, 2609, 3383, 3534], 'expressed': [2447, 2614, 3388, 3539], 'percentage': [2450, 2617, 3391, 3542], 'presented': [2457, 2624, 3397, 3548], 'mean': [2459, 2626, 3399, 3550], '±S.E.': [2460, 2627], 'four': [2462, 2629, 3403, 3554], 'six': [2464, 2631, 3405, 3556], 'separate': [2465, 2632, 3406, 3557], 'determinations.': [2466, 2633, 3407, 3558], '*,p': [2467, 2634], '<': [2468, 2485, 2635, 2652, 2790, 2861, 3030, 3410, 3561, 4110, 4187], '0.01': [2469, 2486, 2636, 2653], 'inhibitors.': [2482, 2499, 2649, 2666], '**,': [2483, 2650], 'p': [2484, 2651, 2789, 3409, 3560, 3636, 4186], 'TG-activated': [2493, 2660, 3418, 3569], 'Open': [2500, 3433], 'table': [2501, 3434], 'new': [2504, 3437, 4576], 'tab': [2505, 3438], 'Human': [2506, 3439, 4372], 'cell-permeant': [2669], 'peptide': [2670], 'isolated': [2671], 'Jaspis': [2673], 'johnstoni': [2674], 'stabilization': [2679, 3593], 'useful': [2707], 'tool': [2708], 'studying': [2710], 'further': [2711, 2797, 3776, 4393], 'SMCE.': [2720, 4245], 'elongate': [2726], 'organize': [2728], 'exclusively': [2731], 'periphery,': [2735], 'near': [2736], 'resulted': [2774, 2905, 3726], 'significant': [2777, 4114], 'enhancement': [2778], '(n': [2786, 2858, 2950, 4095, 4278], '=': [2787, 2859, 2951, 3005, 3138, 3177, 3194, 3235, 3637, 3640, 3668, 3700, 3737, 3749, 3772, 4096, 4184, 4279, 4425, 4460], '4;': [2788], '0.001;': [2791], 'Table': [2792, 4137], 'observed': [2803, 3742, 4623], 'JP-treated': [2809, 3000], 'attenuates': [2824], 'concentration-dependent': [2829, 4062], 'manner': [2830, 4609], '2,A–C).': [2832], 'significantly': [2837, 2940, 3020, 3621, 4073, 4172], '48.9': [2839], '4.0': [2841], '77.7': [2843], '5.4%': [2845], 'respectively': [2857, 4108], '6;p': [2860], '0.001).': [2862, 2954, 3031, 4188], 'cytosolic': [2871, 4290], 'levels': [2873], 'nor': [2874, 4293], 'As': [2886, 3032, 3131], 'substantial': [2908], 'physiological': [2918], 'agonist': [2919, 2937, 2984], '(0.5': [2921], 'unit/ml)': [2922], 'Ca2+.': [2928], 'peak': [2931, 2977], '1,000': [2942], '60': [2944], '328': [2946], '22': [2948], '6;': [2952, 4185, 4280], 'p<': [2953, 4281], '(1': [2961, 4711], 'EGTA': [2963], 'added),': [2964], 'thrombin-evoked': [2971, 3022], '[Ca2+]i.': [2974], '233': [2987, 2995], '12': [2989], '19': [2997], 'E;n': [3004], '6).': [3006, 3195, 4426], 'If': [3007], 'consider': [3009], 'Ca2+stimulated': [3013], '(see': [3016], 'Procedures"),': [3018], '67.1': [3026], '1.8%': [3028], '(p': [3029, 4109], 'secretory': [3035], 'pathway,': [3036], 'preventing': [3048], 'exocytosis,': [3049], 'might': [3054, 4364], 'prevent': [3055], 'necessary': [3063], 'To': [3069, 3774, 3876], 'investigate': [3070], 'whether': [3071, 3791, 4362], 'network': [3075], 'maintenance': [3080, 4477], 'studied': [3085], 'effects': [3087, 4115, 4127, 4621], 'stimulated': [3102, 3145, 3189, 3212, 3304, 3455], 'TG.': [3104, 3130], 'vehicle': [3124, 3331, 3482], 'A(control': [3136], 'min)': [3140, 4712], 'clearly': [3144], 'point': [3148], 'time.': [3150], 'blocked': [3159], 'A;n': [3176], '4).': [3178, 3641, 3750, 3773, 4461], 'Under': [3179], '(TableII;': [3192], 'n': [3193, 3234, 3639, 3736, 3748, 3771, 4183, 4424, 4459], 'confirmed': [3199], '(data': [3218, 4123], 'shown)': [3220], 'well': [3222], 'completely': [3224], 'reversing': [3225], 'II;': [3233, 3735], '4).Table': [3236], 'IIEffect': [3237], 'preactivatedStimulatory': [3264], 'agentControlLatrunculin': [3265], 'ACyt': [3266], 'DCyt': [3267], '+': [3269, 3431, 3582], 'JP%': [3270], '0.0100.0': [3274, 3276, 3278], '0.0TG132.6': [3280], '2.2100.6': [3282], '2.9*104.0': [3284], '4.4*194.7': [3286], '2.5*Human': [3288], 'suspended': [3291, 3442], 'Ca2+-free': [3294, 3445], 'TG,': [3308, 3459], 'later': [3312, 3463], 'plus': [3325, 3476], '3.': [3341, 3492], 'CaCl2': [3342, 3493], '(final': [3343, 3494], 'concentration': [3344, 3495], 'μm)': [3346, 3497], 'later.': [3354, 3505], 'S.E.': [3401, 3552], '*,': [3408, 3559], '0.05': [3411, 3562], 'JP.': [3432, 3583], 'Ca2+entry': [3623, 4273], '(Fig.3': [3634, 3764], 'B;': [3635], '0.085,': [3638], 'experiments': [3643], 'carried': [3645], 'out': [3646], 'reversal': [3650], 'action': [3653], 'affinity': [3662], '(KD': [3667, 3699], '15': [3669], 'nm)': [3670, 3702], 'greater': [3694], '(21.Urbanik': [3703], 'E.': [3704, 3999], 'Ware': [3705], 'B.R.': [3706], '1989;': [3710], '181-187Crossref': [3712], 'Simultaneous': [3718], '4)': [3738], 'similar': [3739], 'alone': [3745], 'I;': [3747, 4182], 'inhibitory': [3756], 'C;': [3765], 'compare': [3766], 'involvement': [3778, 4240], 'used': [3785, 4236, 4593], 'independent': [3787], 'means': [3788], 'check': [3790], 'could': [3796], 'interfere': [3797], 'communication': [3800], 'Recent': [3807], 'phosphorylation': [3812], 'moesin,': [3815], 'ezrin,': [3816], 'radixin': [3818], 'family': [3819], 'mediation': [3825], 'cross-linking': [3828], '(22.Tsukita': [3832], 'Yonemura': [3834], 'Tsuikita': [3836], 'Trends': [3838], 'Sci.': [3840], '22:': [3842], '53-58Abstract': [3843], '(274)': [3849], '23.Hishiya': [3852, 3926], 'Ohnishi': [3854, 3928], 'Tamura': [3856, 3930], 'Nakamura': [3858, 3932], 'F.': [3859, 3933, 4034], '26705-26712Abstract': [3865, 3939], '(43)': [3873, 3947], 'induce': [3877], 'phosphorylation-dependent': [3878], 'association': [3879], 'actin-binding': [3882], 'phosphatase': [3896], 'condensation': [3962], '24.Shinoki': [3990], 'N.': [3991, 4036], 'Sakon': [3992, 4023], 'Kambayashi': [3994, 4025], 'Ikeda': [3996], 'Oiki': [3998], 'Okuyama': [4000], 'Fujitana': [4002], 'K.': [4003, 4032], 'Yano': [4004], 'Kawasaki': [4006, 4027], 'Monden': [4008], '59:': [4014], '368-375Crossref': [4015], '(24)': [4018], '25.Yano': [4021], 'Senda': [4029], 'Tanaka': [4031], 'Yamada': [4033], 'Shibata': [4035], '307:': [4040], '439-449Crossref': [4041], '(64)': [4044], 'caused': [4060], 'reduction': [4063], '(Fig.4).': [4070], 'store-regulated': [4075], '26.8': [4079], '6.9,': [4081], '55.1': [4082], '3.9,': [4084], '67.2': [4085], '3.1,': [4087], '69.3': [4088], '4.0,': [4090], '72.3': [4092], '1.3%': [4094], '6)': [4097], 'concentrations': [4099], '3,': [4101], '10,': [4102], '30,': [4103], '100,': [4104], '0.05)': [4111], 'shown).': [4125], 'Exposure': [4139], 'appeared': [4150], 'content,': [4155], 'difference': [4158], 'statistically': [4161], 'significant.': [4162], 'pretreatment': [4164], 'Brefeldin': [4189, 4283], 'specifically': [4192], '(28.Miller': [4196], 'S.G.': [4197], 'Carnell': [4198], 'Moore': [4200], 'H.H.': [4201], 'Cell': [4203, 4350], '1992;': [4205], '118:': [4206], '267-283Crossref': [4207], '(174)': [4210], '29.Dong': [4213], 'Gao': [4215], 'López': [4217], '1998;': [4222], '273:': [4223], '31449-31454Abstract': [4224], '(63)': [4232], '5,A': [4251], 'B,': [4253], '78.2': [4275], '6.1%': [4277], '0.01).': [4282], 'level,': [4292], 'stores,': [4306], '5,': [4324], 'andB).': [4326], '(30.Donaldson': [4339], 'Lippincott-Schwartz': [4341], 'Bloom': [4343], 'G.S.': [4344], 'Kreis': [4345], 'T.E.': [4346], 'Klausner': [4347], 'R.D.': [4348], '111:': [4353], '2295-2306Crossref': [4354], '(292)': [4357], 'examined': [4361], 'reactivated': [4366, 4412], 'removal': [4368], 'preincubated': [4375], 'indicated': [4404], 'that,': [4405], 'secretion,': [4408], '5C;': [4423], 'D;': [4458], 'finding': [4463], 'furthermore': [4481], 'indicates': [4482], 'nonspecific': [4488], 'chelator': [4493], 'channel': [4497], 'blocker.': [4498], 'signaling': [4513], 'great': [4516], 'relevance.': [4517], 'remained': [4534], 'Current': [4536], 'hypotheses': [4537], 'centered': [4539], 'either': [4541], 'released': [4545], 'ER.': [4562], 'Using': [4563], 'SMCE,': [4572], 'provide': [4575], 'insights': [4577], 'monomeric': [4636], 'G-actin': [4637], '1:1': [4640], 'complex': [4641], 'findings': [4660], 'showed,': [4661], 'agreement': [4663], 'previous': [4665], '"treadmilling"': [4681], 'extremely': [4686], 'slow.': [4687], 'Interestingly,': [4688], 'times': [4700], 'short': [4709], 'increases': [4716], 'SM': [4717]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2054675070', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-16T08:52:46.606512', 'created_date': '2016-06-24'}