Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2054535330', 'doi': 'https://doi.org/10.1371/journal.pone.0043331', 'title': 'Global Transcriptome Analysis of the Scorpion Centruroides noxius: New Toxin Families and Evolutionary Insights from an Ancestral Scorpion Species', 'display_name': 'Global Transcriptome Analysis of the Scorpion Centruroides noxius: New Toxin Families and Evolutionary Insights from an Ancestral Scorpion Species', 'publication_year': 2012, 'publication_date': '2012-08-17', 'ids': {'openalex': 'https://openalex.org/W2054535330', 'doi': 'https://doi.org/10.1371/journal.pone.0043331', 'mag': '2054535330', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22912855', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3422302'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0043331', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043331&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043331&type=printable', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050009238', 'display_name': 'Martha Rendón‐Anaya', 'orcid': 'https://orcid.org/0000-0002-8047-223X'}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}, {'id': 'https://openalex.org/I68368234', 'display_name': 'Center for Research and Advanced Studies of the National Polytechnic Institute', 'ror': 'https://ror.org/009eqmr18', 'country_code': 'MX', 'type': 'facility', 'lineage': ['https://openalex.org/I59361560', 'https://openalex.org/I68368234']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Martha Rendón-Anaya', 'raw_affiliation_strings': ['Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), Cuernavaca, Morelos, México', 'Laboratorio Nacional de Genómica para la Biodiversidad, Centro de Investigación y de Estudios Avanzados (CINVESTAV), Irapuato, Guanajuato, México'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), Cuernavaca, Morelos, México', 'institution_ids': ['https://openalex.org/I8961855']}, {'raw_affiliation_string': 'Laboratorio Nacional de Genómica para la Biodiversidad, Centro de Investigación y de Estudios Avanzados (CINVESTAV), Irapuato, Guanajuato, México', 'institution_ids': ['https://openalex.org/I68368234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054768445', 'display_name': 'Luis Delaye', 'orcid': 'https://orcid.org/0000-0003-4193-2720'}, 'institutions': [{'id': 'https://openalex.org/I68368234', 'display_name': 'Center for Research and Advanced Studies of the National Polytechnic Institute', 'ror': 'https://ror.org/009eqmr18', 'country_code': 'MX', 'type': 'facility', 'lineage': ['https://openalex.org/I59361560', 'https://openalex.org/I68368234']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Luis Delaye', 'raw_affiliation_strings': ['Departamento de Ingeniería Genética, Centro de Investigación y de Estudios Avanzados [CINVESTAV], Irapuato, Guanajuato, México'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Ingeniería Genética, Centro de Investigación y de Estudios Avanzados [CINVESTAV], Irapuato, Guanajuato, México', 'institution_ids': ['https://openalex.org/I68368234']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032759906', 'display_name': 'Lourival D. Possani', 'orcid': 'https://orcid.org/0000-0001-6357-2661'}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Lourival D. Possani', 'raw_affiliation_strings': ['Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, UNAM, Cuernavaca, Morelos, Mexico.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, UNAM, Cuernavaca, Morelos, Mexico.', 'institution_ids': ['https://openalex.org/I8961855']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5004095859', 'display_name': 'Alfredo Herrera‐Estrella', 'orcid': 'https://orcid.org/0000-0002-4589-6870'}, 'institutions': [{'id': 'https://openalex.org/I68368234', 'display_name': 'Center for Research and Advanced Studies of the National Polytechnic Institute', 'ror': 'https://ror.org/009eqmr18', 'country_code': 'MX', 'type': 'facility', 'lineage': ['https://openalex.org/I59361560', 'https://openalex.org/I68368234']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Alfredo Herrera-Estrella', 'raw_affiliation_strings': ['Laboratorio Nacional de Genómica para la Biodiversidad, Centro de Investigación y de Estudios Avanzados (CINVESTAV), Irapuato, Guanajuato, México'], 'affiliations': [{'raw_affiliation_string': 'Laboratorio Nacional de Genómica para la Biodiversidad, Centro de Investigación y de Estudios Avanzados (CINVESTAV), Irapuato, Guanajuato, México', 'institution_ids': ['https://openalex.org/I68368234']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1805, 'currency': 'USD', 'value_usd': 1805, 'provenance': 'doaj'}, 'apc_paid': {'value': 1805, 'currency': 'USD', 'value_usd': 1805, 'provenance': 'doaj'}, 'fwci': 7.117, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 78, 'citation_normalized_percentile': {'value': 0.999953, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '7', 'issue': '8', 'first_page': 'e43331', 'last_page': 'e43331'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11353', 'display_name': 'Venomous Animal Envenomation and Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11353', 'display_name': 'Venomous Animal Envenomation and Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11818', 'display_name': 'Nicotinic Acetylcholine Receptors Study', 'score': 0.9781, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/scorpion-venoms', 'display_name': 'Scorpion Venoms', 'score': 0.79208267}, {'id': 'https://openalex.org/keywords/telson', 'display_name': 'Telson', 'score': 0.6053389}, {'id': 'https://openalex.org/keywords/buthidae', 'display_name': 'Buthidae', 'score': 0.53449243}, {'id': 'https://openalex.org/keywords/scorpion-toxin', 'display_name': 'Scorpion toxin', 'score': 0.5123106}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8532076}, {'id': 'https://openalex.org/C2777884321', 'wikidata': 'https://www.wikidata.org/wiki/Q19125', 'display_name': 'Scorpion', 'level': 3, 'score': 0.8352418}, {'id': 'https://openalex.org/C2910159647', 'wikidata': 'https://www.wikidata.org/wiki/Q19125', 'display_name': 'Scorpion Venoms', 'level': 4, 'score': 0.79208267}, {'id': 'https://openalex.org/C2779448229', 'wikidata': 'https://www.wikidata.org/wiki/Q3386847', 'display_name': 'Venom', 'level': 2, 'score': 0.6697628}, {'id': 'https://openalex.org/C162317418', 'wikidata': 'https://www.wikidata.org/wiki/Q252857', 'display_name': 'Transcriptome', 'level': 4, 'score': 0.6425556}, {'id': 'https://openalex.org/C2778913507', 'wikidata': 'https://www.wikidata.org/wiki/Q952557', 'display_name': 'Telson', 'level': 4, 'score': 0.6053389}, {'id': 'https://openalex.org/C2776611219', 'wikidata': 'https://www.wikidata.org/wiki/Q132129', 'display_name': 'Buthidae', 'level': 4, 'score': 0.53449243}, {'id': 'https://openalex.org/C2776676993', 'wikidata': 'https://www.wikidata.org/wiki/Q7435406', 'display_name': 'Scorpion toxin', 'level': 4, 'score': 0.5123106}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.4519874}, {'id': 'https://openalex.org/C78458016', 'wikidata': 'https://www.wikidata.org/wiki/Q840400', 'display_name': 'Evolutionary biology', 'level': 1, 'score': 0.4485421}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.41334763}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.39566723}, {'id': 'https://openalex.org/C90856448', 'wikidata': 'https://www.wikidata.org/wiki/Q431', 'display_name': 'Zoology', 'level': 1, 'score': 0.16975114}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.13560453}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.13294405}, {'id': 'https://openalex.org/C84766238', 'wikidata': 'https://www.wikidata.org/wiki/Q25364', 'display_name': 'Crustacean', 'level': 2, 'score': 0.06636998}, {'id': 'https://openalex.org/C67206012', 'wikidata': 'https://www.wikidata.org/wiki/Q666115', 'display_name': 'Carapace', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019143', 'descriptor_name': 'Evolution, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010802', 'descriptor_name': 'Phylogeny', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012605', 'descriptor_name': 'Scorpions', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D014118', 'descriptor_name': 'Toxins, Biological', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015723', 'descriptor_name': 'Gene Library', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016013', 'descriptor_name': 'Likelihood Functions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008800', 'descriptor_name': 'Mexico', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008957', 'descriptor_name': 'Models, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058977', 'descriptor_name': 'Molecular Sequence Annotation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012605', 'descriptor_name': 'Scorpions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013045', 'descriptor_name': 'Species Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014118', 'descriptor_name': 'Toxins, Biological', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014118', 'descriptor_name': 'Toxins, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0043331', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043331&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/78142bd226114ee2a4ad3074ca5b736f', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3422302', 'pdf_url': 'https://europepmc.org/articles/pmc3422302?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422302', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22912855', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0043331', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043331&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14', 'score': 0.88}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 55, 'referenced_works': ['https://openalex.org/W1525649833', 'https://openalex.org/W1545751589', 'https://openalex.org/W1579440051', 'https://openalex.org/W1966266513', 'https://openalex.org/W1967210387', 'https://openalex.org/W1967959869', 'https://openalex.org/W1969018883', 'https://openalex.org/W1973027447', 'https://openalex.org/W1974937986', 'https://openalex.org/W1975814181', 'https://openalex.org/W1976069053', 'https://openalex.org/W1977259479', 'https://openalex.org/W1977651069', 'https://openalex.org/W1985899388', 'https://openalex.org/W1990133426', 'https://openalex.org/W1992670328', 'https://openalex.org/W1996771340', 'https://openalex.org/W1998469753', 'https://openalex.org/W2002893301', 'https://openalex.org/W2004659266', 'https://openalex.org/W2006196344', 'https://openalex.org/W2007058896', 'https://openalex.org/W2016485425', 'https://openalex.org/W2018935710', 'https://openalex.org/W2020175197', 'https://openalex.org/W2023864483', 'https://openalex.org/W2031549439', 'https://openalex.org/W2033178128', 'https://openalex.org/W2038411922', 'https://openalex.org/W2072619702', 'https://openalex.org/W2078174444', 'https://openalex.org/W2080552208', 'https://openalex.org/W2088722891', 'https://openalex.org/W2102649026', 'https://openalex.org/W2111211467', 'https://openalex.org/W2116895571', 'https://openalex.org/W2128114769', 'https://openalex.org/W2130865131', 'https://openalex.org/W2132926880', 'https://openalex.org/W2137015675', 'https://openalex.org/W2139134537', 'https://openalex.org/W2140099453', 'https://openalex.org/W2141506506', 'https://openalex.org/W2144654387', 'https://openalex.org/W2146273335', 'https://openalex.org/W2148350911', 'https://openalex.org/W2151673628', 'https://openalex.org/W2155804510', 'https://openalex.org/W2159957100', 'https://openalex.org/W2160416298', 'https://openalex.org/W2160508108', 'https://openalex.org/W2164154943', 'https://openalex.org/W2192557100', 'https://openalex.org/W2208566223', 'https://openalex.org/W4231029285'], 'related_works': ['https://openalex.org/W886305219', 'https://openalex.org/W4367053455', 'https://openalex.org/W3092146295', 'https://openalex.org/W3037789861', 'https://openalex.org/W2894007837', 'https://openalex.org/W2809101427', 'https://openalex.org/W2565396082', 'https://openalex.org/W2466972008', 'https://openalex.org/W2461124270', 'https://openalex.org/W2119204609'], 'abstract_inverted_index': {'Scorpion': [0], 'venoms': [1], 'have': [2], 'been': [3, 25], 'studied': [4], 'for': [5], 'decades,': [6], 'leading': [7], 'to': [8, 27, 120, 123], 'the': [9, 28, 47, 76, 80, 87, 108, 140, 146, 195, 203, 220, 232, 248, 251, 261, 268, 276], 'identification': [10], 'of': [11, 13, 30, 46, 79, 114, 142, 145, 160, 181, 194, 219, 234, 250, 270], 'hundreds': [12], 'different': [14, 68], 'toxins': [15, 124], 'with': [16, 54], 'medical': [17, 286], 'and': [18, 35, 85, 91, 101, 132, 175, 185, 192, 205, 212, 222, 237, 240, 244, 287], 'pharmacological': [19, 236], 'implications.': [20], 'However,': [21], 'little': [22], 'emphasis': [23], 'has': [24], 'given': [26], 'description': [29], 'these': [31, 229], 'arthropods': [32], 'from': [33, 72, 75, 86, 285], 'cellular': [34, 221], 'evolutionary': [36, 288], 'perspectives.': [37, 289], 'In': [38], 'this': [39, 169, 258], 'report,': [40], 'we': [41], 'describe': [42], 'a': [43, 55, 216, 281], 'transcriptomic': [44], 'analysis': [45, 159], 'Mexican': [48], 'scorpion': [49, 81, 129, 252, 277], 'Centruroides': [50, 278], 'noxius': [51, 279], 'Hoffmann,': [52, 280], 'performed': [53], 'pyrosequencing': [56], 'platform.': [57], 'Three': [58], 'independent': [59], 'sequencing': [60, 211], 'experiments': [61], 'were': [62, 99, 118], 'carried': [63], 'out,': [64], 'each': [65], 'including': [66], 'three': [67, 96], 'cDNA': [69], 'libraries': [70], 'constructed': [71], 'RNA': [73, 149], 'extracted': [74], 'whole': [77], 'body': [78], 'after': [82, 92, 186], 'telson': [83], 'removal,': [84], 'venom': [88, 93, 187], 'gland': [89], 'before': [90, 184], 'extraction.': [94], 'Over': [95], 'million': [97], 'reads': [98], 'obtained': [100, 256], 'assembled': [102, 196], 'in': [103, 127, 168, 172, 202, 228, 257, 275], 'almost': [104], '19000': [105], 'isogroups.': [106], 'Within': [107], 'telson-specific': [109], 'sequences,': [110], '72': [111], 'isogroups': [112, 197], '(0.4%': [113], 'total': [115], 'unique': [116], 'transcripts)': [117], 'found': [119], 'be': [121], 'similar': [122], 'previously': [125], 'reported': [126], 'other': [128], 'species,': [130, 170], 'spiders': [131], 'sea': [133], 'anemones.': [134], 'The': [135, 254], 'annotation': [136, 213], 'pipeline': [137], 'also': [138], 'revealed': [139], 'presence': [141], 'important': [143], 'elements': [144], 'small': [147], 'non-coding': [148], 'processing': [150], 'machinery,': [151], 'as': [152, 154], 'well': [153], 'microRNA': [155], 'candidates.': [156], 'A': [157], 'phylogenomic': [158], 'concatenated': [161], 'essential': [162], 'genes': [163, 271], 'evidenced': [164], 'differential': [165], 'evolution': [166], 'rates': [167], 'particularly': [171], 'ribosomal': [173], 'proteins': [174], 'proteasome': [176], 'components.': [177], 'Additionally,': [178], 'statistical': [179], 'comparison': [180], 'transcript': [182], 'abundance': [183], 'extraction': [188], 'showed': [189], 'that': [190, 225, 265, 272], '3%': [191], '2%': [193], 'had': [198], 'higher': [199], 'expression': [200], 'levels': [201], 'active': [204], 'replenishing': [206], 'gland,': [207], 'respectively.': [208], 'Thus,': [209], 'our': [210], 'strategies': [214], 'provide': [215], 'general': [217], 'view': [218], 'molecular': [223], 'processes': [224], 'take': [226], 'place': [227], 'arthropods,': [230], 'allowed': [231], 'discovery': [233], 'new': [235], 'biotechnological': [238], 'targets': [239], 'uncovered': [241], 'several': [242], 'regulatory': [243], 'metabolic': [245], 'responses': [246], 'behind': [247], 'assembly': [249], 'venom.': [253], 'results': [255], 'report': [259], 'represent': [260], 'first': [262], 'high-throughput': [263], 'study': [264], 'thoroughly': [266], 'describes': [267], 'universe': [269], 'are': [273], 'expressed': [274], 'highly': [282], 'relevant': [283], 'organism': [284]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2054535330', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 11}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 12}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2025-01-11T08:59:46.467826', 'created_date': '2016-06-24'}