Publication Information

{'id': 'https://openalex.org/W2053908667', 'doi': 'https://doi.org/10.1097/qai.0b013e3181938fc9', 'title': 'A Randomized, Open-Label Study of a Nucleoside Analogue Reverse Transcriptase Inhibitor-Sparing Regimen in Antiretroviral-Naive HIV-Infected Patients', 'display_name': 'A Randomized, Open-Label Study of a Nucleoside Analogue Reverse Transcriptase Inhibitor-Sparing Regimen in Antiretroviral-Naive HIV-Infected Patients', 'publication_year': 2009, 'publication_date': '2009-02-23', 'ids': {'openalex': 'https://openalex.org/W2053908667', 'doi': 'https://doi.org/10.1097/qai.0b013e3181938fc9', 'mag': '2053908667', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19242263'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1097/qai.0b013e3181938fc9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S157460402', 'display_name': 'JAIDS Journal of Acquired Immune Deficiency Syndromes', 'issn_l': '1525-4135', 'issn': ['1525-4135', '1944-7884'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1097/qai.0b013e3181938fc9', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5061614395', 'display_name': 'Marianne Harris', 'orcid': 'https://orcid.org/0000-0002-9056-4533'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': True, 'raw_author_name': 'Marianne Harris', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018441519', 'display_name': 'Hélène C. F. Côté', 'orcid': 'https://orcid.org/0000-0002-0399-5141'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Hélène Côté', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087644688', 'display_name': 'Claudia Ochoa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Claudia Ochoa', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018167374', 'display_name': 'Clotilde Allavena', 'orcid': 'https://orcid.org/0000-0003-1010-1270'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Clotilde Allavena', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004612964', 'display_name': 'Eugènia Negredo', 'orcid': 'https://orcid.org/0000-0001-5298-1734'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Eugenia Negredo', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112550292', 'display_name': 'Anona Thorne', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': True, 'raw_author_name': 'Anona Thorne', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061097917', 'display_name': 'Pedro Cahn', 'orcid': 'https://orcid.org/0000-0002-9381-1931'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Pedro Cahn', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053198362', 'display_name': 'Carlos Zala', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Carlos Zala', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110215337', 'display_name': 'François Raffi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Francois Raffi', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I4210106546', 'https://openalex.org/I141945490', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028130303', 'display_name': 'Bonaventura Clotet', 'orcid': 'https://orcid.org/0000-0003-3232-4598'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Bonaventura Clotet', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046341729', 'display_name': 'Joel Singer', 'orcid': 'https://orcid.org/0000-0003-4936-4086'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': True, 'raw_author_name': 'Joel Singer', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074441717', 'display_name': 'Julio Montaner', 'orcid': 'https://orcid.org/0000-0002-6201-9829'}, 'institutions': [{'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}, {'id': 'https://openalex.org/I4210106546', 'display_name': 'Fundación Huésped', 'ror': 'https://ror.org/01p47g940', 'country_code': 'AR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210106546']}, {'id': 'https://openalex.org/I4210153460', 'display_name': 'Hospital Universitari Germans Trias i Pujol', 'ror': 'https://ror.org/04wxdxa47', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I157913058', 'https://openalex.org/I4210153292', 'https://openalex.org/I4210153460']}], 'countries': ['AR', 'CA', 'ES'], 'is_corresponding': False, 'raw_author_name': 'Julio Montaner', 'raw_affiliation_strings': ['Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia'], 'affiliations': [{'raw_affiliation_string': 'Canadian HIV Trials Network, Vancouver, British Columbia, Canada, †Department of Pathology and Laboratory Medicine University of British Columbia, Vancouver, British Columbia, Canada, ‡Department of Infectious Disease Fundacion Huesped, University of Buenos Aires, Buenos Aires, Argentina, §Department of Infectious Diseases and Department of Clinical Research Nantes University Hospital Hotel Dieu, Nantes, France, ¶HIV Unit and Iriscaixa Foundation, Hospital Universitari "Germans Trias i Pujol" Badalona, Barcelona, Spain #Department of Medicine University of British Columbia Vancouver, British Columbia', 'institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5061614395', 'https://openalex.org/A5112550292', 'https://openalex.org/A5046341729'], 'corresponding_institution_ids': ['https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460', 'https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460', 'https://openalex.org/I141945490', 'https://openalex.org/I4210106546', 'https://openalex.org/I4210153460'], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.510226, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 82, 'max': 83}, 'biblio': {'volume': '50', 'issue': '3', 'first_page': '335', 'last_page': '337'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11655', 'display_name': 'HIV-related health complications and treatments', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/2711', 'display_name': 'Emergency Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nevirapine', 'display_name': 'Nevirapine', 'score': 0.7924843}, {'id': 'https://openalex.org/keywords/regimen', 'display_name': 'Regimen', 'score': 0.73364866}, {'id': 'https://openalex.org/keywords/ritonavir', 'display_name': 'Ritonavir', 'score': 0.6679289}, {'id': 'https://openalex.org/keywords/lopinavir', 'display_name': 'Lopinavir', 'score': 0.6143244}, {'id': 'https://openalex.org/keywords/lopinavir/ritonavir', 'display_name': 'Lopinavir/ritonavir', 'score': 0.56434304}, {'id': 'https://openalex.org/keywords/reverse-transcriptase-inhibitor', 'display_name': 'Reverse-transcriptase inhibitor', 'score': 0.556353}, {'id': 'https://openalex.org/keywords/abacavir', 'display_name': 'Abacavir', 'score': 0.54088503}, {'id': 'https://openalex.org/keywords/mitochondrial-toxicity', 'display_name': 'Mitochondrial toxicity', 'score': 0.50671655}], 'concepts': [{'id': 'https://openalex.org/C2779130552', 'wikidata': 'https://www.wikidata.org/wiki/Q263713', 'display_name': 'Nevirapine', 'level': 5, 'score': 0.7924843}, {'id': 'https://openalex.org/C2780216070', 'wikidata': 'https://www.wikidata.org/wiki/Q198504', 'display_name': 'Zidovudine', 'level': 4, 'score': 0.7786182}, {'id': 'https://openalex.org/C2781413609', 'wikidata': 'https://www.wikidata.org/wiki/Q7308373', 'display_name': 'Regimen', 'level': 2, 'score': 0.73364866}, {'id': 'https://openalex.org/C2777869810', 'wikidata': 'https://www.wikidata.org/wiki/Q422631', 'display_name': 'Lamivudine', 'level': 4, 'score': 0.71435916}, {'id': 'https://openalex.org/C2779298103', 'wikidata': 'https://www.wikidata.org/wiki/Q422618', 'display_name': 'Ritonavir', 'level': 5, 'score': 0.6679289}, {'id': 'https://openalex.org/C2777182164', 'wikidata': 'https://www.wikidata.org/wiki/Q422585', 'display_name': 'Lopinavir', 'level': 5, 'score': 0.6143244}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6071117}, {'id': 'https://openalex.org/C2781392899', 'wikidata': 'https://www.wikidata.org/wiki/Q422618', 'display_name': 'Lopinavir/ritonavir', 'level': 5, 'score': 0.56434304}, {'id': 'https://openalex.org/C2777351918', 'wikidata': 'https://www.wikidata.org/wiki/Q421559', 'display_name': 'Reverse-transcriptase inhibitor', 'level': 5, 'score': 0.556353}, {'id': 'https://openalex.org/C2909970146', 'wikidata': 'https://www.wikidata.org/wiki/Q421559', 'display_name': 'Nucleoside Reverse Transcriptase Inhibitor', 'level': 5, 'score': 0.54613376}, {'id': 'https://openalex.org/C2779465607', 'wikidata': 'https://www.wikidata.org/wiki/Q304330', 'display_name': 'Abacavir', 'level': 5, 'score': 0.54088503}, {'id': 'https://openalex.org/C2777071529', 'wikidata': 'https://www.wikidata.org/wiki/Q12796879', 'display_name': 'Mitochondrial toxicity', 'level': 3, 'score': 0.50671655}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.44518256}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.42078137}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.41884828}, {'id': 'https://openalex.org/C142462285', 'wikidata': 'https://www.wikidata.org/wiki/Q2528140', 'display_name': 'Viral load', 'level': 3, 'score': 0.34200108}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.31441593}, {'id': 'https://openalex.org/C2993143319', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral therapy', 'level': 4, 'score': 0.14690977}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.10143921}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.0817754}, {'id': 'https://openalex.org/C2780593183', 'wikidata': 'https://www.wikidata.org/wiki/Q6844', 'display_name': 'Hepatitis B virus', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D017320', 'descriptor_name': 'HIV Protease Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D018894', 'descriptor_name': 'Reverse Transcriptase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018791', 'descriptor_name': 'CD4 Lymphocyte Count', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017320', 'descriptor_name': 'HIV Protease Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017320', 'descriptor_name': 'HIV Protease Inhibitors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D061466', 'descriptor_name': 'Lopinavir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019829', 'descriptor_name': 'Nevirapine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019829', 'descriptor_name': 'Nevirapine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D019829', 'descriptor_name': 'Nevirapine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D011744', 'descriptor_name': 'Pyrimidinones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011744', 'descriptor_name': 'Pyrimidinones', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D011744', 'descriptor_name': 'Pyrimidinones', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D018894', 'descriptor_name': 'Reverse Transcriptase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018894', 'descriptor_name': 'Reverse Transcriptase Inhibitors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D019438', 'descriptor_name': 'Ritonavir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019438', 'descriptor_name': 'Ritonavir', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D019438', 'descriptor_name': 'Ritonavir', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D019562', 'descriptor_name': 'Viral Load', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1097/qai.0b013e3181938fc9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S157460402', 'display_name': 'JAIDS Journal of Acquired Immune Deficiency Syndromes', 'issn_l': '1525-4135', 'issn': ['1525-4135', '1944-7884'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://journals.lww.com/jaids/fulltext/2009/03010/a_randomized,_open_label_study_of_a_nucleoside.16.aspx', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19242263', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1097/qai.0b013e3181938fc9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S157460402', 'display_name': 'JAIDS Journal of Acquired Immune Deficiency Syndromes', 'issn_l': '1525-4135', 'issn': ['1525-4135', '1944-7884'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.78, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 10, 'referenced_works': ['https://openalex.org/W1989924554', 'https://openalex.org/W1991485152', 'https://openalex.org/W2008681391', 'https://openalex.org/W2041841997', 'https://openalex.org/W2044748199', 'https://openalex.org/W2130312329', 'https://openalex.org/W2136097824', 'https://openalex.org/W2137768386', 'https://openalex.org/W2162769217', 'https://openalex.org/W2317283086'], 'related_works': ['https://openalex.org/W3162888079', 'https://openalex.org/W3035595114', 'https://openalex.org/W3014800957', 'https://openalex.org/W2959634722', 'https://openalex.org/W2576465868', 'https://openalex.org/W2407014618', 'https://openalex.org/W2400222829', 'https://openalex.org/W2162955592', 'https://openalex.org/W2100483898', 'https://openalex.org/W2015441944'], 'abstract_inverted_index': {'To': [0], 'the': [1, 45, 131, 149, 154, 165, 253, 262, 273, 278, 325, 338, 363, 420, 425, 430, 433, 492, 525, 529, 563, 594, 618, 626, 669, 677, 703, 728, 737, 762, 798, 805, 842, 853, 877, 884, 893, 904, 909, 920, 925, 954, 964, 973, 1036, 1041, 1050, 1062, 1087, 1092, 1113, 1119, 1125], 'Editor:': [2], 'A': [3], 'decrease': [4], 'in': [5, 83, 94, 127, 272, 331, 334, 432, 497, 520, 593, 598, 603, 617, 625, 639, 709, 720, 727, 745, 778, 797, 804, 856, 863, 883, 897, 919, 940, 972, 1013, 1017, 1071, 1080, 1103], 'ratio': [6, 85, 340, 482, 750, 1077], 'of': [7, 17, 38, 48, 60, 153, 164, 244, 252, 341, 400, 438, 528, 540, 556, 584, 600, 614, 644, 656, 668, 676, 705, 751, 764, 845, 858, 880, 889, 906, 963, 978, 1007, 1038, 1065, 1089, 1095, 1184, 1190, 1198, 1204, 1211, 1216, 1241, 1244], 'mitochondrial': [8, 18, 890], 'DNA': [9, 12], 'to': [10, 64, 80, 89, 162, 250, 324, 544, 560, 581, 648, 660, 673, 715, 743, 754, 776, 786, 818, 826, 870, 903, 931, 983, 996, 1002, 1046, 1110], 'nuclear': [11], '(mtDNA:nDNA),': [13], 'a': [14, 53, 346, 538, 553, 937, 997, 1003], 'possible': [15], 'marker': [16], 'toxicity,': [19], 'might': [20, 41], 'be': [21, 42, 819, 871, 901, 1054, 1098], 'expected': [22], 'with': [23, 32, 67, 78, 87, 110, 117, 504, 552, 612, 653, 666, 683, 736, 741, 774, 873, 892, 1026, 1029], 'nucleoside': [24], 'analogue': [25], 'reverse': [26], 'transcriptase': [27], 'inhibitors': [28], '(NRTIs)': [29], 'but': [30], 'not': [31, 512, 824, 848, 917, 1053], 'NRTI-sparing': [33, 56, 530, 806, 843, 955, 1093], 'regimens.1-3': [34], 'The': [35, 58, 102, 138, 266, 886, 1107, 1170], 'dyslipidemic': [36], 'effects': [37, 47, 859, 946], 'lopinavir/ritonavir': [39], '(LPV/r)4,5': [40], 'counteracted': [43], 'by': [44, 148, 234, 345, 537, 834, 992], 'beneficial': [46], 'nevirapine': [49], '(NVP),6,7': [50], 'making': [51], 'this': [52, 61, 128, 604, 898, 1014], 'potentially': [54], 'attractive': [55], 'option.': [57], 'objective': [59], 'study': [62, 103, 129, 139, 401, 427, 439, 588, 838, 899, 913, 926, 1114, 1122], 'was': [63, 232, 269, 322, 343, 445, 464, 475, 483], 'compare': [65], 'NVP/LPV/r': [66], '2': [68, 254, 613, 655, 965, 1042], 'NRTI-based': [69, 894], 'regimens,': [70, 533], 'zidovudine/lamivudine': [71], '(ZDV/3TC)': [72], 'plus': [73, 182, 211, 222], 'either': [74, 123, 251, 787, 962], 'NVP': [75, 183, 212, 691, 1039, 1059], 'or': [76, 382, 575, 586, 631, 684, 782, 790], 'LPV/r,': [77], 'respect': [79, 88, 742, 775], '48-week': [81], 'changes': [82, 93, 730, 744, 777, 1070], 'mtDNA:nDNA': [84, 342, 434, 481, 487, 509, 861, 941], 'and': [86, 92, 99, 141, 246, 305, 310, 365, 372, 407, 428, 479, 488, 517, 623, 711, 733, 756, 802, 822, 944, 957, 1009, 1021, 1074, 1116, 1124, 1186, 1214, 1228], 'efficacy,': [90], 'safety,': [91], 'metabolic': [95], 'parameters': [96], 'over': [97, 290, 852], '48': [98, 518, 717, 789, 928], '96': [100, 291, 791, 828, 993], 'weeks.': [101], 'enrolled': [104], 'medically': [105], 'stable': [106], 'antiretroviral-naive': [107, 840], 'HIV-infected': [108], 'adults': [109], 'HIV': [111, 312, 454, 986, 1127, 1176], 'RNA': [112, 313, 455, 987], '>5000': [113], 'copies': [114, 457, 989], 'per': [115, 458, 467, 699, 990], 'milliliter,': [116, 459], 'no': [118], 'upper': [119], 'CD4': [120, 132, 307, 461, 473, 693], 'limit': [121], 'for': [122, 135, 261, 293, 329, 370, 419, 424, 429, 491, 546, 562, 949, 958, 1056], 'gender,': [124], 'as': [125, 353, 386, 610, 664, 908, 1100], 'enrollment': [126], 'predated': [130], 'threshold': [133], 'recommendations': [134], 'starting': [136, 706], 'NVP.8': [137], 'protocol': [140], 'subject': [142], 'informed': [143], 'consent': [144], 'form': [145], 'were': [146, 159, 285, 358, 378, 413, 417, 441, 590, 636, 725, 770, 814, 823, 916, 947, 970, 1023, 1078], 'approved': [147], 'Research': [150, 205, 1218], 'Ethics': [151], 'Boards': [152], 'participating': [155], 'institutions.': [156], 'Eligible': [157], 'patients': [158, 431, 503, 602, 616, 881, 950, 980, 1115], 'randomized': [160, 392, 647, 659, 672, 982], 'equally': [161], '1': [163, 398, 585, 652], '3': [166, 245, 421, 493, 574, 630, 643, 670], 'treatment': [167, 422, 522], 'arms:': [168], 'LPV/r': [169, 223, 267, 1033, 1066], '533/133': [170], 'mg': [171, 185, 199, 214, 219, 225, 259], '[4': [172], 'Kaletra': [173, 227], 'capsules': [174], '(Abbott': [175], 'Laboratories,': [176], 'North': [177], 'Chicago,': [178], 'IL)]': [179], 'twice': [180, 195, 209, 215, 220, 229], 'daily': [181, 210, 221, 260], '200': [184, 213, 258], '[1': [186, 200], 'Viramune': [187], 'tablet': [188, 203], '(Boehringer': [189], 'Ingelheim': [190], 'Pharmaceuticals': [191], 'Inc,': [192], 'Ridgefield,': [193], 'CT)]': [194], 'daily;': [196, 216], 'ZDV/3TC': [197, 217, 564, 801, 907], '300/150': [198, 218], 'Combivir': [201], 'film-coated': [202], '(GlaxoSmithKline,': [204], 'Triangle': [206], 'Park,': [207], 'NC)]': [208], '400/100': [224], '(3': [226, 650], 'capsules)': [228], 'daily.': [230], 'Randomization': [231], 'stratified': [233], 'country': [235], '(Canada,': [236], 'France,': [237], 'Spain,': [238], 'Argentina)': [239], 'using': [240, 362, 380], 'variable': [241], 'block': [242], 'sizes': [243], '6.': [247], 'Patients': [248, 284], 'allocated': [249], 'NVP-containing': [255, 1082], 'regimens': [256, 855, 895], 'received': [257], 'first': [263], '14': [264], 'days.': [265], 'dose': [268, 399], 'adjusted': [270], 'upwards': [271], 'LPV/r/NVP': [274, 547, 595, 649, 846, 984, 1027, 1096], 'arm,': [275, 596, 1015], 'based': [276, 1085], 'on': [277, 860, 953, 1067, 1086], 'pharmacokinetic': [279], 'interaction': [280], 'between': [281, 360, 515, 731, 739, 772], 'these': [282, 812, 867], 'agents.9': [283], 'evaluated': [286], 'at': [287, 396, 702, 808, 1118], 'regular': [288], 'intervals': [289], 'weeks': [292, 519, 929], 'complete': [294], 'blood': [295, 321, 507], 'cell': [296, 308, 462, 694], 'counts,': [297], 'chemistry': [298], 'including': [299], 'liver': [300, 686], 'enzymes,': [301], 'lactate,': [302], 'fasting': [303], 'glucose': [304, 783], 'lipids,': [306], 'count,': [309], 'plasma': [311], '(Roche': [314], 'Amplicor': [315], 'assay': [316, 352], 'version': [317], '1.5).': [318], 'Venous': [319], 'whole': [320, 426, 506], 'shipped': [323], 'British': [326, 1180, 1191, 1194, 1245, 1248], 'Columbia': [327, 1192, 1246, 1249], 'Centre': [328], 'Excellence': [330], 'HIV/AIDS': [332], 'Laboratory': [333, 1187], 'Vancouver,': [335, 1179, 1193, 1247], 'Canada,': [336], 'where': [337], 'relative': [339], 'determined': [344], 'semiquantitative': [347], 'real-time': [348], 'polymerase': [349], 'chain': [350], 'reaction-based': [351], 'described': [354], 'previously.2,3': [355], 'Continuous': [356], 'variables': [357, 377], 'compared': [359, 379, 551, 611, 665], 'groups': [361, 423, 494, 740], 'Kruskal-Wallis': [364], 'Wilcoxon': [366], 'rank': [367], 'sum': [368], 'tests': [369], '3-group': [371], '2-group': [373], 'comparisons,': [374], 'respectively.': [375], 'Categorical': [376], 'χ2': [381], 'Fisher': [383], 'exact': [384], 'test,': [385], 'appropriate.': [387], 'Safety': [388], 'analysis': [389], 'included': [390, 882, 918], 'all': [391, 1112], 'subjects': [393, 412, 765, 914], 'who': [394, 680, 915, 951, 960], 'took': [395, 961], 'least': [397], 'drug.': [402], 'Between': [403], 'February': [404], '3,': [405], '2003,': [406], 'July': [408], '8,': [409], '2004,': [410], '77': [411], 'enrolled.': [414], 'Baseline': [415], 'characteristics': [416], 'similar': [418, 948], 'analysis.': [435, 885], 'Overall,': [436], '75%': [437], 'participants': [440], 'male,': [442], 'median': [443, 460, 472, 480, 539, 554], 'age': [444], '37': [446], 'years': [447], '[interquartile': [448], 'range': [449], '(IQR)': [450], '33-42],': [451], '58%': [452], 'had': [453, 692, 985], '>75,000': [456], 'count': [463], '210': [465], 'cells': [466, 698], 'cubic': [468, 700], 'millimeter': [469, 701], '(IQR': [470, 477, 542, 558], '130-271),': [471], 'fraction': [474], '16%': [476], '10-20),': [478], '1.93': [484], '(IQR:': [485], '1.70-2.08).': [486], 'efficacy': [489], 'results': [490, 868], 'are': [495, 718, 766, 1043], 'shown': [496, 719, 936], 'Table': [498, 721], '1.': [499, 722], 'Among': [500], '26': [501, 601, 615, 979], 'unselected': [502], 'available': [505], 'samples,': [508], 'ratios': [510, 862], 'did': [511, 847], 'change': [513, 939], 'significantly': [514], 'baseline': [516, 714, 732, 785], 'any': [521, 850], 'arm.': [523, 628], 'In': [524], '2-way': [526], 'comparison': [527], 'vs.': [531], 'NRTI-containing': [532], 'mtDNA:': [534], 'nDNA': [535], 'decreased': [536, 803], '3%': [541], '−19': [543], '3)': [545], '(n': [548, 567], '=': [549, 568, 571], '7)': [550], 'increase': [555], '11%': [557], '−5': [559], '24)': [561], 'arms': [565, 773, 799], 'combined': [566], '19;': [569], 'P': [570], '0.16).': [572], 'Grade': [573, 629], 'grade': [576, 632], '4': [577, 608, 633], 'adverse': [578, 634, 932, 1011, 1063], 'events': [579, 635, 1012], 'leading': [580], 'permanent': [582], 'discontinuation': [583], 'more': [587, 1004, 1024], 'drugs': [589], 'predominantly': [591], 'observed': [592, 638, 726, 771, 896, 971], 'occurring': [597], '9': [599], 'arm': [605, 620, 807], '(5': [606], 'rash,': [607], 'transaminitis),': [609, 654], 'NVP/ZDV/3TC': [619, 661], '(both': [621], 'rashes)': [622], '0/25': [624], 'LPV/r/ZDV/3TC': [627], 'frequently': [637], 'women': [640, 646, 658, 671, 679], 'receiving': [641], 'NVP:': [642], '6': [645, 977], 'rashes,': [651], '10': [657], '(2': [662], 'rashes),': [663], 'none': [667], 'LPV/r/ZDV/3TC.': [674], 'Two': [675], '5': [678], 'experienced': [681], 'rash': [682, 1008, 1020], 'without': [685], 'enzyme': [687], 'elevations': [688], 'while': [689], 'taking': [690], 'counts': [695], 'above': [696], '250': [697], 'time': [704], 'NVP.': [707], 'Changes': [708], 'lipids': [710], 'lactate': [712], 'from': [713, 784], 'week': [716, 734, 788, 809, 827], 'Similar': [723], 'trends': [724], 'lipid': [729], '96,': [735], 'differences': [738, 769, 813, 969], 'high-density': [746], 'lipoprotein': [747, 780], 'cholesterol': [748, 753, 781, 1073], '(HDL),': [749], 'total': [752, 1075], 'HDL,': [755], 'triglycerides': [757], 'remaining': [758], 'statistically': [759], 'significant,': [760], 'although': [761], 'numbers': [763], 'smaller.': [767], 'No': [768], 'low-density': [779], '(P': [792, 829], '>': [793, 830], '0.2).': [794], 'Lactate': [795], 'increased': [796], 'containing': [800], '48;': [810], 'however,': [811, 866, 1049], 'likely': [815], 'too': [816], 'small': [817], 'clinically': [820], 'relevant': [821], 'sustained': [825], '0.2).TABLE': [831], '1:': [832], 'Results': [833], 'Treatment': [835], 'ArmIn': [836], 'our': [837, 1090], 'among': [839], 'adults,': [841], 'regimen': [844, 956, 1094], 'demonstrate': [849], 'advantages': [851], 'ZDV/3TC-containing': [854], 'terms': [857], 'peripheral': [864], 'blood;': [865], 'need': [869], 'interpreted': [872], 'some': [874], 'caution': [875], 'given': [876], 'limited': [878], 'number': [879], 'apparent': [887], 'lack': [888], 'toxicity': [891, 1037], 'may': [900, 934, 1034, 1052, 1060], 'due': [902, 930, 995], 'selection': [905], 'NRTI': [910], 'backbone.': [911], 'Also,': [912], 'mtDNA': [921], 'analysis,': [922], 'having': [923], 'left': [924], 'before': [927], 'events,': [933], 'have': [935], 'greater': [938], 'ratio.': [942], 'Virologic': [943], 'immunologic': [945], 'remained': [952], 'those': [959], 'ZDV/3TC-based': [966], 'regimens.': [967], 'However,': [968, 1084], 'intent-to-treat': [974], 'analysis:': [975], 'only': [976], '(23%)': [981], '<50': [988], 'milliliter': [991], 'weeks,': [994], 'high': [998], 'dropout': [999], 'rate': [1000], 'related': [1001], 'frequent': [1005], 'occurrence': [1006], 'hepatic': [1010], 'especially': [1016], 'women.': [1018], 'NVP-related': [1019], 'hepatitis': [1022], 'common': [1025], 'than': [1028], 'NVP/ZDV/3TC,': [1030], 'suggesting': [1031], 'that': [1032], 'potentiate': [1035], 'when': [1040], 'administered': [1044], 'together': [1045], 'naive': [1047], 'patients;': [1048], 'same': [1051], 'true': [1055], 'treatment-experienced': [1057], 'patients.10-12': [1058], 'counteract': [1061], 'impact': [1064], 'lipids:': [1068], 'favorable': [1069], 'HDL': [1072], 'cholesterol:HDL': [1076], 'seen': [1079], 'both': [1081], 'arms.': [1083], 'findings': [1088], 'study,': [1091], 'cannot': [1097], 'recommended': [1099], 'first-line': [1101], 'therapy': [1102], 'treatment-naive': [1104], 'patients.': [1105], 'ACKNOWLEDGMENTS': [1106], 'authors': [1108], 'wish': [1109], 'thank': [1111], 'staff': [1117], 'CTN': [1120, 1171], '177': [1121, 1172], 'sites': [1123], 'Canadian': [1126], 'Trials': [1128, 1177], 'Network.': [1129], 'Marianne': [1130], 'Harris,': [1131], 'MD*': [1132], 'Hélène': [1133], 'Côté,': [1134], 'PhD†': [1135], 'Claudia': [1136], 'Ochoa,': [1137], 'MD‡': [1138, 1155], 'Clotilde': [1139], 'Allavena,': [1140], 'MD§': [1141], 'Eugenia': [1142], 'Negredo,': [1143], 'MD,': [1144, 1151, 1158, 1162], 'PhD¶': [1145, 1163], 'Anona': [1146], 'Thorne,': [1147], 'MSc*': [1148], 'Pedro': [1149], 'Cahn,': [1150], 'PhD‡': [1152], 'Carlos': [1153], 'Zala,': [1154], 'Francois': [1156], 'Raffi,': [1157], 'PhD§': [1159], 'Bonaventura': [1160], 'Clotet,': [1161], 'Joel': [1164], 'Singer,': [1165], 'PhD*': [1166], 'Julio': [1167], 'Montaner,': [1168], 'MD#': [1169], 'Study': [1173], 'Team': [1174], '*Canadian': [1175], 'Network': [1178], 'Columbia,': [1181, 1195], 'Canada': [1182, 1196], '†Department': [1183], 'Pathology': [1185], 'Medicine': [1188, 1242], 'University': [1189, 1203, 1220, 1243], '‡Department': [1197], 'Infectious': [1199, 1212], 'Disease': [1200], 'Fundacion': [1201], 'Huesped': [1202], 'Buenos': [1205, 1207], 'Aires': [1206], 'Aires,': [1208], 'Argentina': [1209], '§Department': [1210], 'Diseases': [1213], 'Department': [1215], 'Clinical': [1217], 'Nantes': [1219], 'Hospital': [1221, 1231], 'Hotel': [1222], 'Dieu,': [1223], 'Nantes,': [1224], 'France': [1225], '¶HIV': [1226], 'Unit': [1227], 'Iriscaixa': [1229], 'Foundation': [1230], 'Universitari': [1232], '"Germans': [1233], 'Trias': [1234], 'i': [1235], 'Pujol"': [1236], 'Badalona,': [1237], 'Barcelona,': [1238], 'Spain': [1239], '#Department': [1240]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2053908667', 'counts_by_year': [{'year': 2022, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-08T22:50:25.718967', 'created_date': '2016-06-24'}