Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2053595048', 'doi': 'https://doi.org/10.1016/j.gene.2013.10.054', 'title': 'Restriction enzyme cutting site distribution regularity for DNA looping technology', 'display_name': 'Restriction enzyme cutting site distribution regularity for DNA looping technology', 'publication_year': 2013, 'publication_date': '2013-11-06', 'ids': {'openalex': 'https://openalex.org/W2053595048', 'doi': 'https://doi.org/10.1016/j.gene.2013.10.054', 'mag': '2053595048', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24211387'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.gene.2013.10.054', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75702506', 'display_name': 'Gene', 'issn_l': '0378-1119', 'issn': ['0378-1119', '1879-0038'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044022801', 'display_name': 'Ying Shang', 'orcid': 'https://orcid.org/0000-0002-8119-6433'}, 'institutions': [{'id': 'https://openalex.org/I52158045', 'display_name': 'China Agricultural University', 'ror': 'https://ror.org/04v3ywz14', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I52158045']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ying Shang', 'raw_affiliation_strings': ['Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'institution_ids': ['https://openalex.org/I52158045']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100331348', 'display_name': 'Nan Zhang', 'orcid': 'https://orcid.org/0009-0004-3415-4072'}, 'institutions': [{'id': 'https://openalex.org/I52158045', 'display_name': 'China Agricultural University', 'ror': 'https://ror.org/04v3ywz14', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I52158045']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Nan Zhang', 'raw_affiliation_strings': ['Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'institution_ids': ['https://openalex.org/I52158045']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103166505', 'display_name': 'Pengyu Zhu', 'orcid': 'https://orcid.org/0000-0003-1612-2419'}, 'institutions': [{'id': 'https://openalex.org/I52158045', 'display_name': 'China Agricultural University', 'ror': 'https://ror.org/04v3ywz14', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I52158045']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Pengyu Zhu', 'raw_affiliation_strings': ['Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'institution_ids': ['https://openalex.org/I52158045']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100438253', 'display_name': 'Yunbo Luo', 'orcid': 'https://orcid.org/0000-0001-5346-5870'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yunbo Luo', 'raw_affiliation_strings': ['The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049698883', 'display_name': 'Kunlun Huang', 'orcid': 'https://orcid.org/0000-0002-2350-5859'}, 'institutions': [{'id': 'https://openalex.org/I52158045', 'display_name': 'China Agricultural University', 'ror': 'https://ror.org/04v3ywz14', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I52158045']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Kunlun Huang', 'raw_affiliation_strings': ['Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China', 'institution_ids': []}, {'raw_affiliation_string': 'Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'institution_ids': ['https://openalex.org/I52158045']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058694330', 'display_name': 'Wenying Tian', 'orcid': None}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenying Tian', 'raw_affiliation_strings': ['The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063844874', 'display_name': 'Wentao Xu', 'orcid': 'https://orcid.org/0000-0002-2302-8490'}, 'institutions': [{'id': 'https://openalex.org/I52158045', 'display_name': 'China Agricultural University', 'ror': 'https://ror.org/04v3ywz14', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I52158045']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Wentao Xu', 'raw_affiliation_strings': ['Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China'], 'affiliations': [{'raw_affiliation_string': 'The Supervision, Inspection and Testing Center of Genetically Modified Organisms, Ministry of Agriculture, Beijing 100083, China', 'institution_ids': []}, {'raw_affiliation_string': 'Laboratory of Food Safety, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China', 'institution_ids': ['https://openalex.org/I52158045']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5049698883', 'https://openalex.org/A5063844874'], 'corresponding_institution_ids': ['https://openalex.org/I52158045', 'https://openalex.org/I52158045'], 'apc_list': {'value': 2940, 'currency': 'USD', 'value_usd': 2940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.129, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.474227, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 72, 'max': 76}, 'biblio': {'volume': '534', 'issue': '2', 'first_page': '222', 'last_page': '228'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10878', 'display_name': 'CRISPR and Genetic Engineering', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10878', 'display_name': 'CRISPR and Genetic Engineering', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12929', 'display_name': 'Animal Genetics and Reproduction', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11426', 'display_name': 'Genetically Modified Organisms Research', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/restriction-site', 'display_name': 'Restriction site', 'score': 0.7268344}, {'id': 'https://openalex.org/keywords/restriction-fragment', 'display_name': 'Restriction fragment', 'score': 0.6470058}, {'id': 'https://openalex.org/keywords/restriction-digest', 'display_name': 'Restriction digest', 'score': 0.54643184}, {'id': 'https://openalex.org/keywords/restriction-map', 'display_name': 'Restriction map', 'score': 0.5383663}], 'concepts': [{'id': 'https://openalex.org/C128319531', 'wikidata': 'https://www.wikidata.org/wiki/Q219715', 'display_name': 'Restriction enzyme', 'level': 3, 'score': 0.8135237}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7987178}, {'id': 'https://openalex.org/C58301748', 'wikidata': 'https://www.wikidata.org/wiki/Q1074969', 'display_name': 'Restriction site', 'level': 4, 'score': 0.7268344}, {'id': 'https://openalex.org/C84289048', 'wikidata': 'https://www.wikidata.org/wiki/Q7316314', 'display_name': 'Restriction fragment', 'level': 3, 'score': 0.6470058}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.5598012}, {'id': 'https://openalex.org/C2889275', 'wikidata': 'https://www.wikidata.org/wiki/Q7316313', 'display_name': 'Restriction digest', 'level': 4, 'score': 0.54643184}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.53889745}, {'id': 'https://openalex.org/C170673058', 'wikidata': 'https://www.wikidata.org/wiki/Q780686', 'display_name': 'Restriction map', 'level': 4, 'score': 0.5383663}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.42601818}, {'id': 'https://openalex.org/C168007829', 'wikidata': 'https://www.wikidata.org/wiki/Q857299', 'display_name': 'Restriction fragment length polymorphism', 'level': 4, 'score': 0.4202603}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.16136563}, {'id': 'https://openalex.org/C22744801', 'wikidata': 'https://www.wikidata.org/wiki/Q172778', 'display_name': 'Plasmid', 'level': 3, 'score': 0.13906598}, {'id': 'https://openalex.org/C49105822', 'wikidata': 'https://www.wikidata.org/wiki/Q176996', 'display_name': 'Polymerase chain reaction', 'level': 3, 'score': 0.11024591}], 'mesh': [{'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004262', 'descriptor_name': 'DNA Restriction Enzymes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016678', 'descriptor_name': 'Genome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017360', 'descriptor_name': 'Arabidopsis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017360', 'descriptor_name': 'Arabidopsis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004262', 'descriptor_name': 'DNA Restriction Enzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008025', 'descriptor_name': 'Ligases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008025', 'descriptor_name': 'Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012275', 'descriptor_name': 'Oryza', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012275', 'descriptor_name': 'Oryza', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012984', 'descriptor_name': 'Software', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.gene.2013.10.054', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75702506', 'display_name': 'Gene', 'issn_l': '0378-1119', 'issn': ['0378-1119', '1879-0038'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24211387', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W1531456299', 'https://openalex.org/W1605670969', 'https://openalex.org/W1971713880', 'https://openalex.org/W1975870959', 'https://openalex.org/W2004209173', 'https://openalex.org/W2021167041', 'https://openalex.org/W2032065355', 'https://openalex.org/W2045003429', 'https://openalex.org/W2048628486', 'https://openalex.org/W2054981715', 'https://openalex.org/W2059103079', 'https://openalex.org/W2071580868', 'https://openalex.org/W2079991336', 'https://openalex.org/W2098842766', 'https://openalex.org/W2103803613', 'https://openalex.org/W2114570899', 'https://openalex.org/W2117717704', 'https://openalex.org/W2125383928', 'https://openalex.org/W2141623415', 'https://openalex.org/W2146025633', 'https://openalex.org/W2159686532', 'https://openalex.org/W2172157322', 'https://openalex.org/W35318297'], 'related_works': ['https://openalex.org/W4241230163', 'https://openalex.org/W4235228633', 'https://openalex.org/W3199198580', 'https://openalex.org/W2267879925', 'https://openalex.org/W2153259318', 'https://openalex.org/W2146845516', 'https://openalex.org/W2077097444', 'https://openalex.org/W2028702152', 'https://openalex.org/W2000439691', 'https://openalex.org/W1999469577'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2053595048', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-12-16T07:44:52.467640', 'created_date': '2016-06-24'}