Title: Hypoparathyroidism, Pseudohypoparathyroidism, and Pseudo-Pseudohypoparathyroidism
Abstract: Hypoparathyroidism, pseudohypoparathyroidism, and pseudo-pseudohypoparathyroidism are a triad of progressively named and related disorders of interest to both the internist and the ophthalmologist. <h3>Hypoparathyroidism</h3> Hypoparathyroidism is most commonly of the secondary variety, following inadvertent removal or injury of the parathyroid glands during the course of thyroidectomy. Postoperative hypoparathyroidism occurs in approximately 1% of patients with thyrotoxicosis who undergo thyroid surgery.<sup>1</sup>Idiopathic hypoparathyroidism, characterized pathologically by the absence of parathyroid tissue or its replacement by fat, is much less common; Steinberg and Waldron,<sup>2</sup>reporting a case of their own, could find, in reviewing the literature, only 52 other cases. Idiopathic hypoparathyroidism affects both sexes equally; the average age at onset is 17, but the disease may occur as late as age 60.<sup>28</sup> In hypoparathyroidism of either the idiopathic or the postoperative type the decreased secretion or the absence of the parathyroid hormone results in a lowered serum calcium, an
Publication Year: 1961
Publication Date: 1961-02-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 12
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