Title: Evaluation of Acute Myocardial Infarction with Late Enhancement Pattern on MRI Compared with 201Tl and 99mTc-Hydroxymethylenediphosphonate (HMDP) Dual Single Photon Emission Computed Tomography (SPECT) Images
Abstract: The purpose of this study is to evaluate reperfused acute myocardial infarction with late enhancement (LE) pattern on contrast-enhanced magnetic resonance imaging compared with myocardial single photon emission computed tomography (SPECT) images. Materials and Methods: Magnetic resonance and 201Tl and 99mTc-hydroxymethylenediphosphonate SPECT images were obtained from 40 patients within 6 days of reperfused myocardial infarction. We assessed the myocardial LE pattern using the true fast imaging with steady-state free precession sequence after the injection of Gd-DTPA. Patients were classified into 3 groups: group 1 included patients with localized endocardial enhancement; group 2, patients with transmural enhancement; and group 3, patients with LE and a residual defect. Results: There were 9 patients (23%) in group 1, 15 (38%) in group 2, and 15 (38%) in group 3. In 1 patient, LE was not detected (3%). The %201Tl uptake for the infarcted area was 60.7 ± 7.2 (mean ± SD) for group 1, 49.5 ± 12.3 (P < 0.05 vs. group 1) for group 2, and 36.9 ± 8.2 (P < 0.0001 vs. group 1, P = 0.005 vs. group 2) for group 3. An overlap pattern of 201Tl and 99mTc was observed in 9 of the group1 patients (100%) and 9 of the group 2 patients (60%), but was not evident in group 3 (0%). Conclusions: LE with residual defect is an important indicator of microvascular obstruction after reperfusion therapy.
Publication Year: 2007
Publication Date: 2007-11-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 8
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