Title: Chronic atropine treatment causes increase in VIP receptors in rat cerebral cortex
Abstract: Chronic atropine treatment (14 days, 20 mg × day−1 × kg−1 SC) caused a 75% increase in the number of VIP receptors in the rat cerebral cortex. The affinity of these receptors for 125I-VIP was not altered significantly by the atropine treatment. The same treatment led to a 20% decrease in VIP tissue levels. Muscarinic receptor number was also increased by 26%. The results indicate that interactions between VIP- and muscarinic receptors may be of importance in the rat cerebral cortex.
Publication Year: 1984
Publication Date: 1984-03-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 24
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