Publication Information

{'id': 'https://openalex.org/W2051757080', 'doi': 'https://doi.org/10.1186/1755-7682-4-28', 'title': 'Cellular viability effects of fatty acid amide hydrolase inhibition on cerebellar neurons', 'display_name': 'Cellular viability effects of fatty acid amide hydrolase inhibition on cerebellar neurons', 'publication_year': 2011, 'publication_date': '2011-01-01', 'ids': {'openalex': 'https://openalex.org/W2051757080', 'doi': 'https://doi.org/10.1186/1755-7682-4-28', 'mag': '2051757080', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21854612', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3171300'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1755-7682-4-28', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S99858142', 'display_name': 'International Archives of Medicine', 'issn_l': '1755-7682', 'issn': ['1755-7682'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316898', 'host_organization_name': 'International Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310316898'], 'host_organization_lineage_names': ['International Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.1186/1755-7682-4-28', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5000690699', 'display_name': 'Kathia Lueneberg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Kathia Lueneberg', 'raw_affiliation_strings': ['División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México'], 'affiliations': [{'raw_affiliation_string': 'División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México', 'institution_ids': ['https://openalex.org/I8961855']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053340050', 'display_name': 'Guadalupe Domínguez-Gómez', 'orcid': 'https://orcid.org/0000-0003-3906-4493'}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Guadalupe Domínguez', 'raw_affiliation_strings': ['División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México'], 'affiliations': [{'raw_affiliation_string': 'División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México', 'institution_ids': ['https://openalex.org/I8961855']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078181611', 'display_name': 'Óscar Arias-Carrión', 'orcid': 'https://orcid.org/0000-0002-9982-7571'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Oscar Arias-Carrión', 'raw_affiliation_strings': ['Department of Neurology, Philipps‐University Marburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Philipps‐University Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006841144', 'display_name': 'Marcela Palomero‐Rivero', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Marcela Palomero-Rivero', 'raw_affiliation_strings': ['Department of Neurology, Philipps‐University Marburg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, Philipps‐University Marburg, Germany', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077698849', 'display_name': 'Diana Millán‐Aldaco', 'orcid': 'https://orcid.org/0000-0001-5801-1595'}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Diana Millán-Aldaco', 'raw_affiliation_strings': ['División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México'], 'affiliations': [{'raw_affiliation_string': 'División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México', 'institution_ids': ['https://openalex.org/I8961855']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048475501', 'display_name': 'Julio Morán', 'orcid': 'https://orcid.org/0000-0003-4880-8597'}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Julio Morán', 'raw_affiliation_strings': ['División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México'], 'affiliations': [{'raw_affiliation_string': 'División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México', 'institution_ids': ['https://openalex.org/I8961855']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109207644', 'display_name': 'René Drucker-Colı́n', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I8961855', 'display_name': 'Universidad Nacional Autónoma de México', 'ror': 'https://ror.org/01tmp8f25', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I8961855']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'René Drucker-Colín', 'raw_affiliation_strings': ['División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México'], 'affiliations': [{'raw_affiliation_string': 'División de Neurociencias Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, México DF, México', 'institution_ids': ['https://openalex.org/I8961855']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5066484942', 'display_name': 'Eric Murillo-Rodrı́guez', 'orcid': 'https://orcid.org/0000-0001-9307-3783'}, 'institutions': [{'id': 'https://openalex.org/I3132536743', 'display_name': 'Anahuac Mayab University', 'ror': 'https://ror.org/014h2x849', 'country_code': 'MX', 'type': 'education', 'lineage': ['https://openalex.org/I3132536743']}], 'countries': ['MX'], 'is_corresponding': False, 'raw_author_name': 'Eric Murillo-Rodríguez', 'raw_affiliation_strings': ['División Ciencias de la Salud Universidad Anáhuac Mayab Mérida, Laboratorio de Neurociencias Moleculares e Integrativas Escuela de Medicina, Yucatán, México'], 'affiliations': [{'raw_affiliation_string': 'División Ciencias de la Salud Universidad Anáhuac Mayab Mérida, Laboratorio de Neurociencias Moleculares e Integrativas Escuela de Medicina, Yucatán, México', 'institution_ids': ['https://openalex.org/I3132536743']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.279, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.709111, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '4', 'issue': '1', 'first_page': '28', 'last_page': '28'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10414', 'display_name': 'Cannabis and Cannabinoid Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10414', 'display_name': 'Cannabis and Cannabinoid Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11207', 'display_name': 'Alcohol Consumption and Health Effects', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic function and diabetes', 'score': 0.9857, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/palmitoylethanolamide', 'display_name': 'Palmitoylethanolamide', 'score': 0.96994674}, {'id': 'https://openalex.org/keywords/anandamide', 'display_name': 'Anandamide', 'score': 0.91775}, {'id': 'https://openalex.org/keywords/viability-assay', 'display_name': 'Viability assay', 'score': 0.70803046}], 'concepts': [{'id': 'https://openalex.org/C2777767828', 'wikidata': 'https://www.wikidata.org/wiki/Q2159860', 'display_name': 'Palmitoylethanolamide', 'level': 5, 'score': 0.96994674}, {'id': 'https://openalex.org/C2781144285', 'wikidata': 'https://www.wikidata.org/wiki/Q21113274', 'display_name': 'Fatty acid amide hydrolase', 'level': 5, 'score': 0.9369463}, {'id': 'https://openalex.org/C2779783865', 'wikidata': 'https://www.wikidata.org/wiki/Q410228', 'display_name': 'Anandamide', 'level': 5, 'score': 0.91775}, {'id': 'https://openalex.org/C46721173', 'wikidata': 'https://www.wikidata.org/wiki/Q368952', 'display_name': 'Endocannabinoid system', 'level': 3, 'score': 0.71972424}, {'id': 'https://openalex.org/C53227056', 'wikidata': 'https://www.wikidata.org/wiki/Q189152', 'display_name': 'Viability assay', 'level': 3, 'score': 0.70803046}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.5574677}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.53855354}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.43644774}, {'id': 'https://openalex.org/C43759708', 'wikidata': 'https://www.wikidata.org/wiki/Q3749256', 'display_name': 'DNA fragmentation', 'level': 4, 'score': 0.41626102}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.40946406}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.35048568}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3375615}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.32229558}, {'id': 'https://openalex.org/C148001335', 'wikidata': 'https://www.wikidata.org/wiki/Q421237', 'display_name': 'Cannabinoid receptor', 'level': 4, 'score': 0.14654201}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2778938600', 'wikidata': 'https://www.wikidata.org/wiki/Q389934', 'display_name': 'Agonist', 'level': 3, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1755-7682-4-28', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S99858142', 'display_name': 'International Archives of Medicine', 'issn_l': '1755-7682', 'issn': ['1755-7682'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316898', 'host_organization_name': 'International Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310316898'], 'host_organization_lineage_names': ['International Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3171300', 'pdf_url': 'https://europepmc.org/articles/pmc3171300?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171300', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21854612', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/1755-7682-4-28', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S99858142', 'display_name': 'International Archives of Medicine', 'issn_l': '1755-7682', 'issn': ['1755-7682'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316898', 'host_organization_name': 'International Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310316898'], 'host_organization_lineage_names': ['International Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.69, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W1589105407', 'https://openalex.org/W1596533665', 'https://openalex.org/W1629776612', 'https://openalex.org/W1651476949', 'https://openalex.org/W1966440880', 'https://openalex.org/W1968086274', 'https://openalex.org/W1968583173', 'https://openalex.org/W1968917850', 'https://openalex.org/W1972207851', 'https://openalex.org/W1979963836', 'https://openalex.org/W1980151600', 'https://openalex.org/W1986932865', 'https://openalex.org/W1989073099', 'https://openalex.org/W2002347548', 'https://openalex.org/W2003661559', 'https://openalex.org/W2003673986', 'https://openalex.org/W2004848791', 'https://openalex.org/W2011607679', 'https://openalex.org/W2022285221', 'https://openalex.org/W2029492104', 'https://openalex.org/W2035343959', 'https://openalex.org/W2035376023', 'https://openalex.org/W2040634905', 'https://openalex.org/W2045011449', 'https://openalex.org/W2065679828', 'https://openalex.org/W2068567462', 'https://openalex.org/W2073030463', 'https://openalex.org/W2080222756', 'https://openalex.org/W2081786271', 'https://openalex.org/W2084965383', 'https://openalex.org/W2099617879', 'https://openalex.org/W2108294595', 'https://openalex.org/W2113864940', 'https://openalex.org/W2115282475', 'https://openalex.org/W2120773365', 'https://openalex.org/W2122605977', 'https://openalex.org/W2127560837', 'https://openalex.org/W2141374273', 'https://openalex.org/W2153753053', 'https://openalex.org/W2157400187', 'https://openalex.org/W2317618655'], 'related_works': ['https://openalex.org/W2805370393', 'https://openalex.org/W2105546002', 'https://openalex.org/W2073287729', 'https://openalex.org/W2051757080', 'https://openalex.org/W2050346904', 'https://openalex.org/W2048920761', 'https://openalex.org/W2045702564', 'https://openalex.org/W2013840000', 'https://openalex.org/W2001441318', 'https://openalex.org/W1973721274'], 'abstract_inverted_index': {'The': [0, 20], 'endocannabinoid': [1], 'anandamide': [2], '(ANA)': [3], 'participates': [4], 'in': [5, 46, 93], 'the': [6, 12, 29, 33, 52], 'control': [7], 'of': [8, 14, 22], 'cell': [9], 'death': [10, 109], 'inducing': [11], 'formation': [13], 'apoptotic': [15], 'bodies': [16], 'and': [17, 73], 'DNA': [18], 'fragmentation.': [19], 'aim': [21], 'this': [23], 'study': [24], 'was': [25, 76, 110], 'to': [26], 'evaluate': [27], 'whether': [28], 'ANA': [30], 'degrading': [31], 'enzyme,': [32], 'fatty': [34], 'acid': [35], 'amide': [36], 'hydrolase': [37], '(FAAH),': [38], 'would': [39], 'induce': [40], 'cellular': [41, 74, 94, 108, 122], 'death.': [42, 123], 'Experiments': [43], 'were': [44], 'performed': [45], 'cerebellar': [47], 'granule': [48], 'neurons': [49], 'cultured': [50, 82, 99], 'with': [51, 83, 100], 'FAAH': [53], 'inhibitor,': [54], 'URB597': [55, 84], '(25,': [56, 85], '50': [57, 86], 'or': [58, 70, 87, 104, 119], '100': [59, 88], 'nM)': [60, 89, 103], 'as': [61, 63, 67], 'well': [62], 'endogenous': [64], 'lipids': [65], 'such': [66], 'oleoylethanolamide': [68], '(OEA)': [69], 'palmitoylethanolamide': [71], '(PEA)': [72], 'viability': [75], 'determined': [77], 'by': [78], 'MTT': [79], 'test.': [80], 'Neurons': [81], 'displayed': [90], 'a': [91], 'decrease': [92], 'viability.': [95], 'In': [96], 'addition,': [97], 'if': [98], 'OEA': [101, 118], '(25': [102], 'PEA': [105, 120], '(100': [106], 'nM),': [107], 'found.': [111], 'These': [112], 'results': [113], 'further': [114], 'suggest': [115], 'that': [116], 'URB597,': [117], 'promote': [121]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2051757080', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-09T11:32:02.805620', 'created_date': '2016-06-24'}