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3465, 3548, 3593, 3602, 3626, 3641, 4063, 4072, 4133], 'low': [15, 237, 1055, 1597, 1608, 2650, 2811], 'fluid': [16, 24, 238, 246, 537, 678, 1042, 4049], 'shear': [17, 25, 195, 239, 247, 417, 538, 679, 768, 813, 871, 885, 2630, 2652, 2663, 4172, 4182], 'stress,': [18, 240, 814, 1310], 'whereas': [19, 241, 751], 'laminar': [20, 68, 111, 129, 157, 200, 242, 290, 333, 351, 379, 422, 640, 670, 757, 949, 962, 1002, 1103, 1753, 1778, 1828, 1866, 1890, 2619, 2627, 2718, 2852, 2883, 3333, 3510, 3526, 3572, 3662, 3714, 3727, 3980, 4014, 4027, 4098, 4115, 4160, 4179], 'high': [23, 245, 675, 753, 2813], 'stress': [26, 71, 196, 248, 293, 418, 539, 680, 769, 872, 886, 1519, 1672, 2631, 2653, 2664, 3336, 3529, 4183], 'are': [27, 249, 486, 665, 759, 809, 820, 951, 1097, 2818, 3088], 'athero-protective.': [28, 250, 760], 'We': [29, 104, 251, 326, 998, 1807], 'have': [30, 252, 742, 1740, 2339], 'identified': [31, 253, 1741, 3544, 3563], 'a': [32, 145, 192, 213, 254, 367, 414, 435, 489, 541, 743, 938, 1172, 1177, 1319, 1411, 1494, 1512, 1524, 1789, 1873, 2113, 2203, 2263, 2364, 2369, 2459, 2586, 2605, 2613, 2648, 2659, 2673, 2899, 3011, 3027, 3061, 3130, 3149, 3202, 3401, 3479, 3585, 3606, 3968], 'set': [33, 255, 1790], 'genes': [35, 80, 205, 257, 302, 427, 799, 1080, 1222, 1743, 1795, 1825, 1882, 3502, 3565, 3589, 3614, 3637, 3664, 4004, 4039], 'including': [36, 258, 1236, 1311, 1324, 1907, 3590], 'NAD(P)H:quinone': [37, 259, 468, 1259], 'oxidoreductase-1': [38, 260, 469], '(NQO1),': [39, 261], 'heme': [40, 262, 462, 1090], 'oxygenase-1': [41, 263, 463, 1091], '(HO-1),': [42, 264, 1092], 'ferritin': [43, 265, 1468, 1698, 3591, 3761, 3792], '(heavy': [44, 266, 3110, 3118, 3592, 3762], 'light': [46, 268, 3594], 'chains),': [47, 269, 3595], 'microsomal': [48, 270, 1799, 3599], 'epoxide': [49, 271, 1800, 3114, 3600], 'hydrolase,': [50, 272, 1801, 3601], 'glutathione': [51, 273, 1237], 'S-transferase,': [52, 274], 'γ-glutamylcysteine': [54, 276, 1805, 3603], 'synthase,': [55, 277], 'whose': [56, 278, 1744], 'expression': [57, 166, 183, 279, 388, 405, 766, 969, 1008, 1049, 1544, 1745, 1787, 1877, 1909, 2321, 2429, 3717, 3984, 4035, 4092, 4109, 4154], 'is': [58, 280, 565, 642, 727, 1171, 1214, 1379, 1493, 1666, 1746, 1813, 2458, 2742, 3627], 'induced': [59, 281, 1050], 'by': [60, 282, 647, 667, 767, 812, 822, 1051, 1102, 1107, 1749, 2388, 2439, 2749, 2914, 2962, 2975, 3010, 3033, 3041, 3263, 3357, 3507, 3545, 3632, 3993, 4011], 'exposure': [61, 107, 283, 329, 892, 956, 1037, 1304, 1751, 1773, 2570, 3508, 4012, 4023], 'prolonged': [63, 285, 1750], 'physiological': [64, 286, 946], 'levels': [65, 287, 676, 754, 947, 3092, 3989, 4130, 4170, 4191], 'steady': [67, 289, 756], '(shear': [70, 292, 3335, 3528], '=': [72, 294, 3337, 3530], '20': [73, 295, 3338, 3531], 'dyn/cm2)': [74, 296, 2657, 3339, 3532], 'endothelial': [76, 194, 298, 416, 456, 460, 484, 764, 867, 894, 942, 959, 1010, 1039, 1059, 1094, 1700, 1763, 1775, 1839, 1884, 1941, 2622, 2643, 2692, 3719], 'cells': [77, 100, 299, 322, 457, 461, 485, 868, 895, 960, 1011, 1040, 1060, 1594, 1701, 1764, 1776, 1840, 1942, 1985, 3328, 3643], '(EC).': [78, 300], 'These': [79, 186, 301, 408, 862, 1794, 1862, 3703, 4019], 'contain': [81, 303], 'an': [82, 207, 304, 429, 1380, 1504, 1663, 2336, 2931, 3616], 'antioxidant': [83, 204, 305, 426, 448, 1158, 1234, 1403, 1427, 1434, 1881], 'response': [84, 197, 306, 419, 449, 479, 1159, 1168, 1669, 4096, 4113, 4158], 'element': [85, 307, 450, 480, 1160, 1169, 1175, 1816, 2128, 2279], '(ARE)': [86, 308], 'or': [87, 125, 149, 169, 309, 347, 371, 391, 739, 1053, 1853, 2454, 2558, 2591, 2635, 2699, 2720, 2855, 3340, 3443, 3456, 3523, 3618, 3656], 'ARE-like': [88, 310, 3619, 3657], 'transcriptional': [89, 115, 134, 141, 209, 311, 337, 356, 363, 431, 1782, 1843, 3608, 3620], 'regulatory': [90, 312, 1174, 3609, 3621, 3658], 'sequence': [91, 313, 1179, 2908, 2921, 3561, 3651, 3722], 'their': [93, 315, 4079], 'promoters': [94, 316, 3583], 'generally': [96, 318], 'function': [97, 319, 3638], 'protect': [99, 321, 3642], 'against': [101, 323, 1384, 3249, 3495], 'oxidant': [102, 324, 1518], 'stress.': [103, 325, 3634, 3646, 4173], 'demonstrate': [105, 327, 1809], 'that': [106, 328, 731, 934, 1000, 1307, 1420, 1499, 1501, 1772, 1810, 1826, 1865, 1902, 2372, 2609, 2665, 2817, 2843, 2872, 3063, 3503, 3566, 3709, 3979, 4022], 'EC': [109, 331], 'activates': [113, 335, 1780], 'ARE-mediated': [114, 336, 4055], 'activity.': [116, 338, 3440, 3499], 'Mutation': [117, 339], 'ARE': [120, 190, 342, 412, 1213, 1300, 1422, 1812, 2006, 2115, 2127, 2265, 2278, 3617, 3655, 3669], 'from': [121, 343, 494, 888, 1302, 1702, 1917, 2217, 2710, 2714, 2879, 2893, 2935, 2948, 3081, 3253, 3355, 3517, 3539, 3552, 3644, 3660, 3726, 3975, 4102, 4119], 'either': [122, 344, 2577, 3332], 'NQO1': [124, 131, 159, 168, 346, 353, 381, 390, 1822, 1835, 1852, 2010, 2084, 2118, 2420, 2433, 3732, 4062, 4082, 4094, 4132, 4156, 4189], 'HO-1': [126, 133, 348, 355, 1438, 1502, 1546, 1591, 1824, 2199, 2212, 2268, 3822, 3850, 4064, 4111, 4134], 'promoter': [127, 160, 349, 382, 1819, 2047, 2200, 2213, 2472, 3625], 'abolished': [128, 350], 'flow-induced': [130, 158, 352, 380, 1829, 3715], 'activation.': [135, 357], 'Expression': [136, 358], 'antisense': [138, 360, 2337], 'Nrf2': [139, 154, 170, 361, 376, 392, 467, 1854, 2327, 2333, 2367], '(a': [140, 362, 2423], 'factor': [142, 364, 804, 1844, 1846], 'for': [143, 365, 745, 2723, 2738, 2833, 2846, 2870, 2906, 2987, 3070, 3098, 3140, 3343, 3391, 3470, 3533, 3557, 4016, 4029, 4078], 'ARE),': [144, 366, 2036], 'dominant': [146, 368, 2365], 'negative': [147, 369, 2366], 'Nrf2,': [148, 370], 'cytoplasmic': [151, 373, 2424], 'inhibitor': [152, 374, 465, 2425], '(Keap1/INrf2)': [155, 377], 'inhibited': [156, 171, 378, 393, 1855], 'activation': [161, 175, 202, 383, 397, 424, 1857], 'EC.': [163, 185, 385, 407], 'In': [164, 386, 658, 944, 1078, 1660, 1766, 2805, 4127], 'addition,': [165, 387, 1079, 1661], 'tumor': [172, 394, 475], 'necrosis': [173, 395, 476], 'factor-α-induced': [174, 396], 'VCAM-1': [177, 399, 1006, 1048, 1859, 2471], '(vascular': [178, 400], 'cell': [179, 401, 445, 904, 3351], 'adhesion': [180, 402, 446, 905, 909, 973], 'molecule-1)': [181, 403], 'gene': [182, 404, 765, 1007, 1830, 1836, 1860, 1912, 2085, 2094, 2334, 2462, 2477, 2971, 3716, 4056, 4083], 'data': [187, 409, 1863, 2922], 'define': [188, 410], 'as': [191, 413, 633, 652, 801, 1165, 1410, 1437, 1523, 1755, 3090, 3285, 3639], 'novel': [193, 214, 415, 436], 'element.': [198, 420], 'Furthermore,': [199, 421, 1849, 3635], 'via': [206, 428, 1429, 1517, 3211], 'ARE-dependent': [208, 430, 1834], 'mechanism': [210, 218, 432, 440, 1383, 1405], 'may': [211, 433, 770, 873, 1424, 1521, 1868, 1893, 3712], 'represent': [212, 434, 2026], 'athero-protective': [215, 437, 1870], 'anti-inflammatory': [217, 439, 952], 'vasculature.': [221, 443], 'vascular': [444, 548, 555, 903, 1552, 1593, 1905], 'molecule-1': [447, 906], 'chloramphenicol': [451, 2090, 3380, 3396], 'acetyltransferase': [452, 2091], 'glutathioneS-transferase': [453], 'human': [454, 458, 1761, 2009, 2083, 2198, 2211, 2432, 2470], 'aortic': [455, 1762], 'microvascular': [459, 1940], 'cytosolic': [464], 'NF-E2-related': [470, 1845], 'factor-2': [471], 'reactive': [472, 1312], 'oxygen': [473, 1313], 'species': [474, 1314], 'factor-α': [477], 'electrophile': [478, 1167, 1385], 'reverse': [481, 2963], 'transcriptase': [482, 2964], 'Vascular': [483], 'tangential': [490], 'shearing': [491], 'force': [492], 'resulting': [493, 887], 'over': [499, 2690], 'lumenal': [501], 'surface': [502], 'vessel': [505], 'wall': [506], '(1Nerem': [507, 1012], 'R.M.': [508, 514, 918, 920, 1013, 1019, 1142, 1954, 2493, 2518, 2520, 2541], 'Alexander': [509, 921, 1014, 1143, 2490, 2521, 2542], 'R.W.': [510, 922, 1015, 1144, 2491, 2522, 2543], 'Chappell': [511, 1016, 1137, 2536], 'D.C.': [512, 914, 1017, 1138, 2514, 2537], 'Medford': [513, 919, 1018, 1953, 2492, 2519], 'Varner': [515, 915, 1020, 2515], 'S.E.': [516, 916, 1021, 2516], 'Taylor': [517, 1022], 'W.R.': [518, 1023], 'Am.': [519, 854, 989, 1024], 'J.': [520, 787, 855, 980, 990, 1025, 1113, 1440, 1451, 1624, 1640, 1710, 1721, 2059, 2099, 2232, 2494, 2794, 3232, 3236, 3413, 3745, 3776, 3837, 3840, 3865, 3868, 3914], 'Med.': [521, 1026, 1267, 2796], 'Sci.': [522, 836, 1027, 1122, 1200, 1247, 1285, 1357, 1577, 2147, 2350, 3691, 3890, 3952], '1998;': [523, 925, 1028, 1149, 2525, 2548], '316:': [524, 1029], '169-175Crossref': [525, 1030], 'PubMed': [526, 590, 610, 690, 710, 791, 843, 928, 995, 1031, 1073, 1129, 1152, 1189, 1207, 1254, 1271, 1292, 1345, 1364, 1396, 1462, 1487, 1536, 1584, 1630, 1655, 1691, 1730, 1960, 2070, 2108, 2136, 2154, 2243, 2357, 2500, 2528, 2551, 2767, 2800, 3241, 3679, 3698, 3756, 3787, 3817, 3845, 3873, 3897, 3925, 3941, 3959], 'Scopus': [527, 591, 611, 691, 711, 792, 844, 929, 1032, 1074, 1130, 1153, 1190, 1208, 1255, 1272, 1293, 1346, 1365, 1397, 1463, 1488, 1537, 1585, 1631, 1656, 1692, 1961, 2071, 2137, 2155, 2244, 2358, 2501, 2529, 2552, 2768, 2801, 3242, 3680, 3699, 3757, 3788, 3818, 3846, 3874, 3898, 3926, 3942, 3960], '(170)': [528, 1033], 'Google': [529, 593, 613, 624, 693, 713, 724, 794, 846, 860, 931, 996, 1034, 1076, 1132, 1155, 1192, 1210, 1257, 1274, 1295, 1348, 1367, 1399, 1465, 1490, 1539, 1587, 1633, 1658, 1694, 1731, 1963, 2073, 2109, 2139, 2157, 2246, 2360, 2503, 2531, 2554, 2770, 2803, 3244, 3682, 3701, 3759, 3790, 3820, 3848, 3876, 3900, 3928, 3944, 3962], 'Scholar).': [530, 625, 725, 795, 861, 997, 1035, 1077, 1156, 1211, 1296, 1368, 1400, 1491, 1540, 1588, 1659, 1695, 1732, 2074, 2110, 2361, 2504, 2555, 2804, 3245, 3429, 3702], 'The': [531, 1157, 1212, 1369, 2172, 2295, 2402, 2505, 2596, 3394, 3430, 4066], 'nature': [532], 'magnitude': [534], 'this': [536, 1402, 1887, 2807], 'play': [540], 'key': [542], 'role': [543, 1507, 4047], 'maintenance': [546], 'integrity': [549], 'development': [553, 747], 'diseases.': [556], 'For': [557, 796, 1541, 2618, 2638, 3049, 3300, 3346], 'example,': [558, 797, 1542], 'nonrandom': [560], 'distribution': [561], 'atherosclerotic': [563, 749, 779, 1604], 'due': [566], 'at': [567, 816, 1988, 2672, 2826, 3014, 3077, 4162], 'least': [568, 3078], 'part': [570], 'local': [572], 'alterations': [573], 'hemodynamic': [575], 'forces': [576], 'impinging': [577], 'on': [578, 2582, 2744, 3026, 3143, 3195, 3309, 4060, 4168], '(2Asakura': [581, 681], 'T.': [582, 584, 682, 684, 1241, 1279, 1351, 1557, 2052, 3738, 3769, 3884], 'Karino': [583, 683], 'Circ.': [585, 685, 923, 1147, 1955, 2523, 2546], 'Res.': [586, 686, 924, 1148, 1956, 2524, 2547, 2763], '1990;': [587, 687], '66:': [588, 688], '1045-1066Crossref': [589, 689], '(732)': [592, 692], 'Scholar,': [594, 614, 694, 714, 847, 1133, 1349, 1634, 2532, 3683], '3Cornhill': [595, 695], 'J.F.': [596, 696], 'Akins': [597, 697], 'D.': [598, 698, 1115, 1442, 1638], 'Hutson': [599, 699], 'M.': [600, 700, 984, 1617, 1646, 1712, 2231, 2489, 2760, 3228], 'Chandler': [601, 701], 'A.B.': [602, 702], 'Atherosclerosis.': [603, 703], '1980;': [604, 704], '35:': [605, 705], '77-86Abstract': [606, 706], 'Full': [607, 707, 1457, 1459, 1727, 2065, 2067, 2105, 2238, 2240, 3751, 3753, 3782, 3784, 3920, 3922], 'Text': [608, 708, 1458, 1460, 1728, 2066, 2068, 2106, 2239, 2241, 3752, 3754, 3783, 3785, 3921, 3923], 'PDF': [609, 709, 1461, 1729, 2069, 2107, 2242, 3755, 3786, 3924], '(93)': [612, 712], '4Montenegro': [615, 715], 'M.R.': [616, 716], 'Eggen': [617, 717], 'D.A.': [618, 718], 'Lab.': [619, 719], 'Invest.': [620, 720, 1626, 2496], '1968;': [621, 721], '18:': [622, 722], '586-593PubMed': [623, 723], 'At': [626], 'sites': [627, 2044, 2255, 2412, 2448], 'vulnerable': [628], 'lesion': [630, 1605], 'formation': [631, 1606], 'such': [632, 651, 800, 1436], 'branch': [634], 'points,': [635], 'bifurcations,': [636], 'curvatures,': [638], 'unidirectional': [639], 'disturbed,': [643], 'with': [644, 673, 1176, 1757, 1974, 2629, 2658, 3094, 3282, 3317, 3375, 3576, 3666, 4041, 4176, 4181], 'characterized': [646, 666], 'complex': [648], 'patterns': [650, 672], 'reversal.': [657], 'contrast,': [659, 945, 4128], 'lesion-protected': [660], 'more': [668], 'uniform': [669], 'relatively': [674, 752, 3568, 4140], 'It': [726], 'now': [728], 'well': [729], 'accepted': [730], 'oscillatory': [740, 897, 935, 1108, 2639, 2662], 'predilection': [744], 'lesions,': [750], 'Differential': [761, 2861], 'regulation': [762, 1837, 4053], 'be': [771, 1100, 3630], 'involved': [772, 1225], 'focal': [775], 'localization': [776], 'early': [778], '(5Resnick': [781], 'N.': [782, 1140, 1619, 2479, 2539, 3827, 3855], 'Gimbrone': [783, 1116], 'M.A.,': [784, 1117], 'Jr.': [785, 1118], 'FASEB': [786], '1995;': [788, 1251, 1289, 1361, 2062, 3748, 3779, 3894], '9:': [789], '874-882Crossref': [790], '(473)': [793], 'pro-atherogenic': [798], 'platelet-derived': [802], 'growth': [803, 1927], 'monocyte': [806, 1045, 1600], 'chemoattractant': [807], 'protein-1': [808], 'transiently': [810, 3315], 'up-regulated': [811, 1101, 1667, 3631], 'peak': [815], '1.5': [817], 'h,': [818], 'followed': [821, 3009], 'sustained': [823], 'down-regulation': [824, 966], '(6Shyy': [825], 'Y.J.': [826, 2793], 'Hsieh': [827, 1560], 'H.J.': [828], 'Usami': [829], 'S.': [830, 832, 838, 1124, 1202, 1249, 1287, 1359, 1446, 1528, 1573, 1579, 2149, 2352, 2783, 2791, 3693, 3892, 3954], 'Chien': [831], 'Proc.': [833, 1119, 1197, 1244, 1282, 1354, 1574, 2144, 2347, 3688, 3887, 3949], 'Natl.': [834, 1120, 1198, 1245, 1283, 1355, 1575, 2145, 2348, 3689, 3888, 3950], 'Acad.': [835, 1121, 1199, 1246, 1284, 1356, 1576, 2146, 2349, 3690, 3889, 3951], 'U.': [837, 1123, 1201, 1248, 1286, 1358, 1578, 2148, 2351, 3692, 3891, 3953], 'A.': [839, 988, 1125, 1203, 1250, 1288, 1360, 1580, 2150, 2353, 3226, 3694, 3831, 3839, 3859, 3867, 3893, 3955], '1994;': [840, 1186, 1342, 1393, 2133, 3676, 3938], '91:': [841], '4678-4682Crossref': [842], '(324)': [845], '7Hsieh': [848], 'H.J.,': [849], 'Li,': [850], 'N.Q.': [851], 'Frangos': [852], 'J.A.': [853], 'Physiol.': [856, 991], '1991;': [857, 3238], '260:': [858], 'H642-H646PubMed': [859], 'initial': [863, 2985], 'responses': [864, 877, 1553], 'cultured': [866, 1924, 1967], 'applied': [870], 'reflect': [874], 'vivo': [876], 'temporal': [880], 'spatial': [882], 'changes': [883], 'flow.': [890, 2572], 'Prolonged': [891, 955], 'results': [899, 964, 1301, 3087, 3974, 4032], 'up-regulation': [901], '(VCAM-1),1': [907], 'intercellular': [908, 972], 'molecule-1,': [910, 974], 'E-selectin': [912, 976], '(8Chappell': [913, 2513], 'Nerem': [917, 1141, 2517, 2540], '82:': [926, 1150, 2526, 2549], '532-539Crossref': [927, 2527], '(471)': [930, 2530], 'Scholar),': [932, 1258, 1275], 'suggesting': [933], 'imparts': [937], 'proinflammatory': [939], 'phenotype': [940], 'cells.': [943, 1885], 'anti-adhesive.': [954], 'murine': [958, 2326, 2332], 'VCAM-1,': [971], '(9Korenaga': [977], 'R.': [978, 1064, 2344, 2483, 3833, 3861], 'Ando': [979], 'Kosaki': [981], 'K.': [982, 1615, 1636, 1644, 1714, 2227], 'Isshiki': [983], 'Takada': [985], 'Y.': [986, 1470, 1563, 1642, 1650, 1674, 2056, 2096, 3742, 3773, 3800], 'Kamiya': [987], '1997;': [992, 1204, 1627, 1957, 2151, 2764, 2797, 3695, 3917, 3956], '273:': [993], 'C1506-C1515Crossref': [994], 'reported': [999], 'chronic': [1001], 'suppresses': [1004, 1595], 'interleukin-1β-induced': [1005], 'Similarly,': [1036, 4107], 'inhibits': [1044, 1603], 'adherence': [1046], 'TNF-α': [1052], 'oxidized': [1054, 1596], 'density': [1056, 1598, 1609], 'lipoprotein': [1057, 1610], '(10Tsao': [1061], 'P.S.': [1062], 'Buitrago': [1063], 'Chan': [1065], 'J.R.': [1066], 'Cooke': [1067], 'J.P.': [1068], 'Circulation.': [1069, 1651], '1996;': [1070, 1126, 2354], '94:': [1071, 1205, 2152, 3696, 3957], '1682-1689Crossref': [1072], '(259)': [1075], 'encoding': [1081, 1223], 'antioxidants': [1083, 3640], 'manganese': [1084], 'superoxide': [1085, 1088], 'dismutase,': [1086, 1089], 'Cu,Zn': [1087], 'nitric-oxide': [1095], 'synthase': [1096, 3109, 3604], 'demonstrated': [1098], 'but': [1105], 'not': [1106], '(11Topper': [1110], 'J.N.': [1111], 'Cai': [1112], 'Falb': [1114], '93:': [1127, 2355], '10417-10422Crossref': [1128], '(724)': [1131], '12De': [1134, 2533], 'Keulenaer': [1135, 2534], 'G.W.': [1136, 2535], 'Ishizaka': [1139, 2538], 'Griendling': [1145, 2544], 'K.K.': [1146, 2545], '1094-1101Crossref': [1151, 2550], '(533)': [1154, 2553], '(ARE),': [1161], 'also': [1162, 1417, 4166], 'referred': [1163], '(EpRE),': [1170], 'cis-acting': [1173, 1815], 'core': [1178], '5′-RTGACNNNGC-3′': [1181], '(13Jaiswal': [1182, 1338, 1389, 2129, 3672], 'A.K.': [1183, 1263, 1339, 1390, 2058, 2098, 2130, 2346, 3234, 3673, 3744, 3775, 3935], 'Biochem.': [1184, 1340, 1391, 1531, 2131, 3237, 3674, 3936], 'Pharmacol.': [1185, 1341, 1392, 1532, 2132, 3675, 3937], '48:': [1187, 1343, 1394, 2134, 3677, 3939], '439-444Crossref': [1188, 1344, 1395, 2135, 3678, 3940], '(224)': [1191, 1347, 1398, 2138, 3681, 3943], 'Scholar,14Wasserman': [1193, 2140, 3945], 'W.W.': [1194, 2141, 3685, 3946], 'Fahl': [1195, 2142, 3686, 3947], 'W.E.': [1196, 2143, 3687, 3948], '5361-5366Crossref': [1206, 2153, 3697, 3958], '(633)': [1209, 2156, 3700, 3961], 'present': [1215, 1768], '5′-flanking': [1218], 'regions': [1219], 'several': [1221, 3549], 'enzymes': [1224, 1374], 'phase': [1228, 1372, 3432], 'II': [1229, 1373, 3648], 'metabolism': [1230], 'xenobiotics': [1232], 'proteins': [1235, 1435], 'S-transferase': [1238], '(GST)': [1239], '(15Prestera': [1240, 1278], 'Talalay': [1242, 1280, 1352, 3885], 'P.': [1243, 1281, 1353, 3886], '92:': [1252, 1290, 1362, 2498, 3895], '8965-8969Crossref': [1253, 1291, 1363, 3896], '(219)': [1256, 1294, 1366, 3899], 'oxidoreductase': [1260], '(NQO1)': [1261], '(16Jaiswal': [1262], 'Free': [1264], 'Radic.': [1265], 'Biol.': [1266, 1452, 1483, 1687, 1722, 2060, 2100, 2233, 3746, 3777, 3813, 3915], '2000;': [1268, 1484, 1533, 1688, 3814, 3842, 3870], '29:': [1269], '254-262Crossref': [1270], '(386)': [1273], 'glucuronosyltransferase': [1277], 'Activation': [1297], 'cellular': [1303], 'insults': [1306], 'induce': [1308], 'oxidative': [1309, 1387, 1671, 3633, 3645], '(ROS),': [1315], 'ionizing': [1316], 'radiation,': [1317], 'variety': [1320, 1513], 'chemical': [1322], 'entities': [1323], 'electrophilic': [1325], 'compounds,': [1326], 'lipid': [1327], 'peroxides,': [1328], 'antioxidants,': [1329], 'Michael': [1330], 'reaction': [1331, 2390], 'acceptors,': [1332], 'redox-cycling': [1333, 1377], 'polyaromatic': [1334], 'hydrocarbons,': [1335], 'quinones': [1337], '15Prestera': [1350], 'ability': [1370], 'conjugate': [1376], 'chemicals': [1378], 'important': [1381, 1505], 'protective': [1382, 1506], 'toxicity': [1388], 'Although': [1401], 'defense': [1404], 'has': [1406, 1416, 2509], 'been': [1407, 1418, 2340, 2510], 'studied': [1408], 'extensively': [1409], 'hepatic': [1412], 'detoxification': [1413], 'mechanism,': [1414], 'it': [1415], 'suggested': [1419], 'pathway': [1423, 1892], 'contribute': [1425, 1894], 'defenses': [1428], 'induction': [1430], 'other': [1432], 'ARE-regulated': [1433, 1792, 1879], '(17Alam': [1439], 'Stewart': [1441], 'Touchard': [1443], 'C.': [1444, 2485, 3835, 3863], 'Boinapally': [1445], 'Choi': [1447], 'A.M.': [1448, 1621], 'Cook': [1449], 'J.L.': [1450], 'Chem.': [1453, 1723, 2061, 2101, 2234, 3747, 3778, 3916], '1999;': [1454], '274:': [1455], '26071-26078Abstract': [1456], '(1069)': [1464], 'Scholar)': [1466, 1964, 2158, 2247, 2771], '(18Tsuji': [1469, 1673], 'Ayaki': [1471, 1675, 3801], 'H.': [1472, 1559, 1648, 1676, 2229, 3802], 'Whitman': [1473, 1677, 3803], 'S.P.': [1474, 1678, 3804], 'Morrow': [1475, 1679, 3805], 'C.S.': [1476, 1680, 3806], 'Torti': [1477, 1479, 1681, 1683, 3807, 3809], 'S.V.': [1478, 1682, 3808], 'F.M.': [1480, 1684, 3415, 3810], 'Mol.': [1481, 1685, 3811], 'Cell.': [1482, 1686, 3812], '20:': [1485, 1689, 3815], '5818-5827Crossref': [1486, 1690, 3816], '(246)': [1489, 1693, 3819], 'There': [1492], 'considerable': [1495], 'body': [1496], 'evidence': [1498], 'suggests': [1500], 'plays': [1503], 'pathogenesis': [1510], 'diseases': [1515], 'mediated': [1516], 'serve': [1522], 'therapeutic': [1525], 'target': [1526], '(19Immenschuh': [1527], 'Ramadori': [1529], 'G.': [1530, 1706, 3912], '60:': [1534], '1121-1128Crossref': [1535], '(271)': [1538], 'targeted': [1543], 'prevents': [1547], 'pulmonary': [1549], 'inflammatory': [1550, 1911], 'hypoxia': [1555], '(20Minamino': [1556], 'Christou': [1558], 'C.M.': [1561], 'Liu': [1562, 2792], 'Dhawan': [1564], 'V.': [1565], 'Abraham': [1566], 'N.G.': [1567], 'Perrella': [1568], 'M.A.': [1569, 3909], 'Mitsialis': [1570], 'S.A.': [1571], 'Kourembanas': [1572], '2001;': [1581, 1652, 2235], '98:': [1582], '8798-8803Crossref': [1583], '(336)': [1586], 'Induction': [1589], 'lipoprotein-induced': [1599], 'transmigration': [1601], 'receptor': [1611], 'knockout': [1612], 'mice': [1613], '(21Ishikawa': [1614], 'Navab': [1616], 'Leitinger': [1618], 'Fogelman': [1620], 'Lusis': [1622], 'A.J.': [1623], 'Clin.': [1625, 2495], '100:': [1628], '1209-1216Crossref': [1629], '(255)': [1632], '22Ishikawa': [1635], 'Sugawara': [1637], 'Goto': [1639], 'Watanabe': [1641], 'Kawamura': [1643], 'Shiomi': [1645], 'Itabe': [1647], 'Maruyama': [1649], '104:': [1653], '1831-1836Crossref': [1654], '(116)': [1657], 'ferritin,': [1662, 1803], 'iron': [1664], 'sequestrant,': [1665], 'Overexpression': [1696], 'protects': [1699], 'oxidant-mediated': [1703], 'cytolysis': [1704], '(23Balla': [1705], 'Jacob': [1707], 'H.S.': [1708], 'Balla': [1709], 'Rosenberg': [1711], 'Nath': [1713], 'Apple': [1715], 'F.': [1716, 2789], 'Eaton': [1717], 'J.W.': [1718], 'Vercellotti': [1719], 'G.M.': [1720], '1992;': [1724, 2102], '267:': [1725, 2103], '18148-18153Abstract': [1726], 'Through': [1733], 'analysis': [1735, 2916, 3562], 'subtraction': [1737, 2705, 2740, 3515, 3977], 'libraries,': [1738], 'we': [1739, 1770, 3512, 4058], 'numerous': [1742], 'significantly': [1747], 'increased': [1748, 4034, 4100, 4117, 4187], 'compared': [1756, 3093, 3575, 3665, 4040, 4175], 'static': [1758, 2578, 2721, 2857, 3341, 3521, 4042, 4137, 4177], 'culture': [1759, 2589, 3522], '(HAEC).': [1765], 'study,': [1769], 'report': [1771], 'ARE-driven': [1781], 'activity': [1783, 3475], 'increases': [1785], 'genes.': [1793, 4065], 'include': [1796], 'NQO1,': [1797, 3596], 'HO-1,': [1798, 3597], 'GST,': [1802, 3598], 'synthase.': [1806], 'further': [1808, 3071, 3991], 'mediates': [1827], 'expression.': [1831, 1861, 4084], 'Laminar': [1832], 'flow-mediated,': [1833], 'involves': [1841], '2': [1847, 3163, 4089, 4125], '(Nrf2).': [1848], 'co-expression': [1850], 'TNF-α-induced': [1856], 'suggest': [1864], 'exert': [1869], 'effects': [1871, 4067], 'through': [1872], 'coordinated': [1874], 'increase': [1875], 'intracellular': [1880], 'Therefore,': [1886], 'newly': [1888], 'described': [1889, 1945, 2224, 2341, 2512, 2748, 3221], 'flow-regulated': [1891], 'modulation': [1897], 'oxidation-reduction': [1899], '(redox)-sensitive': [1900], 'processes': [1901], 'result': [1903], 'dysfunction,': [1906], 'products.': [1913], 'HAEC': [1914, 2557, 2715, 2949, 3137, 3518, 4025], 'were': [1915, 1932, 1944, 1966, 1986, 2037, 2159, 2179, 2280, 2302, 2437, 2560, 2574, 2624, 2645, 2702, 2708, 2844, 2873, 2888, 2904, 2912, 2927, 2982, 3039, 3058, 3138, 3191, 3208, 3261, 3272, 3304, 3314, 3329, 3353, 3398, 3460, 3466, 3493, 3504, 3543, 3555, 3567, 3990, 4005, 4076], 'obtained': [1916], 'Clonetics,': [1918], 'Inc.': [1919, 3257], '(San': [1920], 'Diego,': [1921], 'CA)': [1922], 'EGM-2': [1926], 'medium': [1928], '(Clonetics,': [1929, 1982], 'Inc.).': [1930, 1983], 'Cells': [1931, 2573], 'used': [1933, 2175, 2298, 2508, 2866, 3069, 3101, 3467], 'between': [1934, 2667, 2821], 'passages': [1935], '5': [1936, 2988, 3366, 3376, 3384, 4185], '9.': [1938], 'Human': [1939], '(HMEC)': [1943], 'previously': [1946, 2225, 2342, 2511, 3222], '(24Chen': [1947], 'X.L.': [1948], 'Tummala': [1949], 'P.E.': [1950], 'Olliff': [1951], 'L.': [1952], '80:': [1958], '305-311Crossref': [1959], '(32)': [1962], 'modified': [1969], 'MCDB': [1970], '131': [1971], '(Invitrogen)': [1972], 'supplemented': [1973], '10%': [1975, 3196], 'fetal': [1976], 'bovine': [1977], 'serum': [1978], 'EGM': [1980], 'Singlequots': [1981], 'All': [1984, 3490], 'maintained': [1987, 2581], '37': [1989], '°C': [1990, 2984, 2994, 2999, 3005], 'under': [1991, 3449], '5%': [1992], 'CO2.': [1993], 'To': [1994, 2111, 2195, 2261, 2362, 2418, 3500, 3971, 4044], 'construct': [1995, 2419], 'p3xARE/Luc': [1996], 'p3xmutARE/Luc,': [1998], 'tandem': [1999], 'repeats': [2000], 'double-stranded': [2002], 'oligonucleotides': [2003], 'spanning': [2004], 'promoter,': [2011, 2119, 2269, 3458], '5′-CAGTCACAGTGACTCAGCAGAATC-3′': [2012], '(for': [2013, 2020], 'wild': [2014], 'type': [2015], 'ARE)': [2016], '5′-CAGTCACAG': [2018], 'TGACTCATAAGAATC': [2019], 'mutated': [2021, 2114, 2160, 2264, 2281], 'ARE,': [2022], 'underlined': [2024, 2184, 2308], 'sequences': [2025, 2847, 3097], 'mutation': [2027], 'conserved': [2029, 2122, 2272], 'nucleotides': [2030, 2124, 2274], 'GC': [2031, 2123, 2187, 2273, 2311, 3736, 3767, 3798, 3825, 3853, 3882, 3905, 3933], 'TA': [2033, 2162, 2185, 2189, 2283, 2313], 'introduced': [2038], 'into': [2039, 2250, 2407, 2443, 2604, 2960], 'SacI': [2041], 'BglII': [2043], 'PGL3': [2046, 2257], 'plasmid': [2048, 2259], '(Promega': [2049], 'Corp.)': [2050], '(25Xie': [2051], 'Belinsky': [2053, 3739, 3770], 'M.,': [2054, 3740, 3771], 'Xu,': [2055, 3741, 3772], 'Jaiswal': [2057, 2097, 2345, 3233, 3743, 3774], '270:': [2063, 3749, 3780], '6894-6900Abstract': [2064, 3750, 3781], '(128)': [2072, 3758, 3789], 'pNQO1CAT1.55': [2075], 'contains': [2076, 2373, 3615], 'coordinates': [2077, 2464], '−1550': [2078], '+110': [2080], 'cloned': [2086, 2249, 2406, 2442], 'upstream': [2087], '(CAT)': [2092], 'reporter': [2093, 2461, 3481], '(26Li': [2095], '15097-15104Abstract': [2104], 'generate': [2112, 2196, 2262, 2363, 2416, 2452], 'pNQO1CAT1.55mARE,': [2120], 'using': [2163, 2221, 2284, 2391, 2726, 2950, 3043, 3265, 3290, 3321, 3400, 3478], 'GeneTailor': [2164, 2286], 'mutagenesis': [2165, 2178, 2287, 2301], 'kit': [2166, 2288, 2731, 2863], 'according': [2167, 2289, 3294, 3484], "manufacturer's": [2169, 2292, 3296, 3487], 'instruction': [2170], '(Invitrogen).': [2171, 2294, 2952], 'PCR': [2173, 2296, 2389], 'primers': [2174, 2223, 2297], '5′-CGCAGTCACAGTGACTCATAAGAATCTGAGCC-3′': [2180], '(forward': [2181, 2305, 2396], 'primer,': [2182, 2306], 'represents': [2186, 2310], 'mutation)': [2190, 2314], '5′-TGAGTCACTGTGACTGCGAATTTGGAAGGC-3′': [2192], '(reverse': [2193, 2317, 2400], 'primer).': [2194, 2318, 2401], 'construct,': [2201], 'pHO-1Luc4.0,': [2202], 'DNA': [2204, 2219, 2370, 2907, 2920, 3558, 3560], 'fragment': [2205, 2371, 2404, 2934], 'containing': [2206, 2323, 2463, 2599, 3152], '4.0': [2207], 'kilobases': [2208], 'region': [2214, 2377], 'was': [2215, 2386, 2405, 2602, 2610, 2683, 2865, 2946, 2958, 2973, 3024, 3068, 3075, 3220, 3251, 3372, 3433, 3476, 4165], 'PCR-amplified': [2216], 'genomic': [2218], '(Promega)': [2220], 'specific': [2222], '(27Kataoka': [2226], 'Handa': [2228], 'Nishizawa': [2230], '276:': [2236], '34074-34081Abstract': [2237], '(115)': [2245], 'MluI': [2252], 'XhoI': [2254, 2411], 'basic': [2258, 2380], '(Promega).': [2260, 3489], 'pHO-1Luc4.0mARE,': [2270], 'inverted': [2277], 'instructions': [2293, 3297, 3488], '5′-GGCGGATTTTGC': [2303], 'TAGATTTTATTGAGTCACCA-3′': [2304], 'AT': [2309], '5′-TGTTTCCCTTCCGCCTAAAACGATCTAAAA-3′': [2316], 'LNCX-Nrf2': [2319], '(an': [2320], 'vector': [2322], 'full-length': [2325, 2431], 'gene)': [2328], 'LNCX-Nrf2R': [2330], '(containing': [2331], 'orientation)': [2338], '(28Venugopal': [2343], '14960-14965Crossref': [2356], '(929)': [2359], 'mutant,': [2368], "Cap'nCollar": [2375], 'homology': [2376], 'leucine-zipper': [2381], 'domain': [2382], '(amino': [2383], 'acids': [2384], '399–598)': [2385], 'amplified': [2387, 2403], 'following': [2393], 'primers:': [2394], '5′-ATGTCACCAGCTCAAGGGCACAGTGC-3′': [2395], 'primer)': [2397], '5′-CCATCCTCCCGAACCTAGTT-3′': [2399], 'NheI': [2409], 'pcDNA3': [2414, 2450], 'pcDNA3DN-Nrf2.': [2417], 'Keap1/INrf2': [2422, 2435], 'Nrf2)': [2427], 'mammalian': [2428], 'vectors,': [2430], 'cDNA': [2436, 2961, 3057, 3514], 'generated': [2438], 'RT-PCR': [2440, 2978, 3103], 'HindIII': [2445], 'XbaI': [2447], 'pcDNA3NQO1': [2453], 'pcDNA3Keap1/INrf2,': [2455], 'respectively.': [2456], 'p85VCAM/CAT': [2457], 'chimeric': [2460], '−85': [2465], '+12': [2467], 'linked': [2473], 'CAT': [2476, 3349, 3439, 3491], '(29Marui': [2478], 'Offermann': [2480], 'M.K.': [2481], 'Swerlick': [2482], 'Kunsch': [2484], 'Rosen': [2486], 'C.A.': [2487], 'Ahmad': [2488], '1993;': [2497], '1866-1874Crossref': [2499], '(978)': [2502], 'system': [2507, 3483], 'Briefly,': [2556], 'HMEC': [2559, 3271, 3303, 3313, 3356], 'seeded': [2561], 'onto': [2562], 'gelatin-coated': [2563, 3310], 'glass': [2564, 2583, 2597, 3311], 'slides': [2565, 2584], 'grown': [2567, 3273, 3305], 'overnight': [2568], 'before': [2569], 'conditions': [2579, 2981, 3342], '(cells': [2580], '150-cm2': [2587], 'tissue': [2588], 'dish)': [2590], 'conditions.': [2595], 'plate': [2598], 'monolayer': [2601], 'inserted': [2603], 'parallel-plate': [2606], 'chamber': [2608], 'installed': [2611], 'closed': [2614], 'loop': [2615], 'system.': [2617], 'experiments,': [2621, 2641, 3302], 'monolayers': [2623, 2644], 'subjected': [2625, 3192, 3407, 3524], '+20': [2633], 'dyn/cm2': [2634, 2671, 4186], '+5': [2636, 2668], 'dyn/cm2.': [2637], 'very': [2649], 'mean': [2651, 2680], '(less': [2654], 'than': [2655], '0.5': [2656], 'superimposed': [2660], 'instantaneous': [2661], 'cycled': [2666], '−5': [2670], 'periodicity': [2674], '1': [2676, 3146, 3166, 3169, 3172, 3175, 3184], 'Hz.': [2677], 'This': [2678, 2736], 'small': [2679], 'component': [2682], 'included': [2684], 'ensure': [2686], 'adequate': [2687], 'media': [2688], 'exchange': [2689], 'monolayer.': [2693], 'After': [2694, 2837, 3017], 'indicated': [2696, 3286, 3319], 'times,': [2697], 'RNA': [2698, 2712, 2823, 2945, 2957, 3084], 'protein': [2700, 3206, 3369], 'samples': [2701, 2824, 3188, 3464], 'collected.': [2703], 'Suppression': [2704], 'hybridization': [2706, 2903], 'libraries': [2707, 2741, 2842, 2887, 3516, 3978], 'prepared': [2709, 3354], 'total': [2711, 2956], 'collected': [2713, 2947], 'cultures': [2722, 4138], '48': [2724, 3534, 4017, 4030, 4105, 4122, 4163], 'h': [2725, 3325, 4031, 4123, 4164], 'Clontech': [2728], 'PCR-SelectTM': [2729], 'Subtraction': [2730], '(Clontech,': [2732], 'Palo': [2733], 'Alto,': [2734], 'CA).': [2735], 'method': [2737, 2746, 2808], 'creating': [2739], 'based': [2743], 'first': [2747, 3707], 'von': [2750], 'Stein': [2751, 2755], 'et': [2752, 2774], 'al.': [2753, 2775], '(30von': [2754], 'O.D.': [2756], 'Thies': [2757], 'W.G.': [2758], 'Hofmann': [2759], 'Nucleic': [2761], 'Acids': [2762], '25:': [2765], '1469-1477Crossref': [2766], '(176)': [2769], 'Mueller': [2773], '(31Mueller': [2776], 'C.G.': [2777], 'Rissoan': [2778], 'M.C.': [2779], 'Salinas': [2780], 'B.': [2781], 'Ait-Yahia': [2782], 'Ravel': [2784], 'O.': [2785], 'Bridon': [2786], 'J.M.': [2787], 'Briere': [2788], 'Lebecque': [2790], 'Exp.': [2795], '186:': [2798], '655-663Crossref': [2799], '(75)': [2802], 'general,': [2806], '"subtracts"': [2809], 'both': [2810], 'abundance': [2814], 'mRNA': [2815, 2941, 3988, 4135, 4190], 'populations': [2816], 'common': [2820, 3607], 'two': [2822], 'while': [2825], 'same': [2828, 3083], 'time': [2829, 4144], 'equalizing': [2830], 'enriching': [2832], 'differentially': [2834, 2874, 3505], 'expressed': [2835, 2848, 3089, 3448, 3506, 3537], 'sequences.': [2836], 'construction': [2838], 'subtracted': [2841], 'enriched': [2845, 3541], 'population': [2854], 'population,': [2858], 'PCR-Select': [2860], 'Screening': [2862], '(Clontech)': [2864], 'rapidly': [2868], 'screen': [2869], 'clones': [2871, 2878, 2897, 3538, 3551], 'expressed.': [2875], 'Approximately': [2876], '800': [2877], 'each': [2880, 2894, 2940, 2970, 3050, 3056, 3540, 3553], 'flow-enriched': [2884, 3573], 'static-enriched': [2886, 3578], 'hybridized': [2889], 'probes': [2891], 'created': [2892], 'library.': [2895, 3579], 'Individual': [2896], 'demonstrating': [2898], 'differential': [2900, 3546], 'pattern': [2901], 'selected': [2905, 3556], 'analysis.': [2909, 2979], 'Clone': [2910], 'identities': [2911], 'determined': [2913, 3040, 3262], 'BLAST': [2915], 'GenBankTM': [2919], 'base.': [2923], 'Oligonucleotide': [2924], 'primer': [2925, 3051, 3099], 'pairs': [2926, 3100], 'designed': [2928], 'amplify': [2930], '∼500-base': [2932], 'pair': [2933], '3′': [2937], 'end': [2938], '(Table': [2942], 'I).': [2943], 'Total': [2944], 'Trizol': [2951], '3': [2953], 'μg': [2954, 3367, 3385], 'reverse-transcribed': [2959], '(Invitrogen),': [2965], 'level': [2968], 'product': [2972], 'measured': [2974, 3477], 'semi-quantitative': [2976, 3994], 'end-point': [2977], 'Cycling': [2980], '95': [2983], 'denaturation': [2986, 2995], 'min,': [2989], '26': [2990], 'cycles': [2991], '94': [2993], '(20': [2996, 3007], 's),': [2997, 3002, 3008], '55': [2998], 'annealing': [3000], '(30': [3001], '72': [3004, 3015], 'extension': [3006, 3013], '7-min': [3012], '°C.': [3016], 'amplification,': [3018], '15': [3019], 'μl': [3020], 'sample': [3023, 3074, 3371], 'electrophoresed': [3025], '1.5%': [3028], 'agarose': [3029], 'gel': [3030], 'stained': [3032], 'ethidium': [3034], 'bromide.': [3035], 'Relative': [3036, 3258], 'band': [3037, 3259], 'intensities': [3038, 3260], 'densitometry': [3042, 3264], 'Bio-Rad': [3045, 3267], 'Quantity': [3046, 3268], 'ONE': [3047], 'software.': [3048, 3270], 'pair,': [3052], 'serial': [3053], 'dilutions': [3054], 'assayed,': [3059], 'dilution': [3062], 'resulted': [3064], 'linear': [3066], 'amplification': [3067], 'experiments.': [3072], 'Each': [3073, 3611], 'assayed': [3076], 'three': [3079], 'times': [3080], 'sample,': [3085], 'relative': [3091], 'β-actin.Table': [3095], 'IDNA': [3096], 'analysisGene': [3104], 'nameGenBank™': [3105], 'Accession': [3106], 'NumberPrimer': [3107], 'sequenceγ-Glutamylcysteine': [3108], 'subunit)M90656F-TGAGGCCAACATGCGAAAAC': [3111], 'R-AAATCACTCCCCAGCGACAATCHeme': [3112], 'oxygenase-1XM_009946F-TTGCTGTAGGGCTTTATGCR-CTGCATTTGAGGCTGAGCCMicrosomal': [3113], 'hydrolaseNM_000120F-CTGGCCCGGCTCTTTCTACGA': [3115], 'R-CAGCAGCTCCACATCCCTCTCAGlutathioneS-transferaseXM_012235F-GTTTTTGCCAATCCAGAAGAC': [3116], 'R-GCTCCCCTCCTACCTAAAATCNQO1J03934F-CCTGGCCCTTGCAATCTTCTACR-CAGCTCGGTCCAATCCCTTCAFerritin': [3117], 'chain)NM_002032F-CTGGCCACTGACAAAAATGACC': [3119], 'R-AACGGCACTTAAGGAATCTGGAFerritin': [3120], '(light': [3121, 3793], 'chain)M10119F-GCGCGAGGGCTACGAG': [3122], 'R-CTATTGGCTGGAGGGAGAGGβ-ActinXM_004814F-ATCGGCGGCTCCATCCR-GGGGCACGAAGGCTCATCF,': [3123], 'forward;': [3124, 3134], 'R,': [3125, 3135], 'reverse.': [3126, 3136], 'Open': [3127, 3965], 'table': [3128, 3966], 'new': [3131, 3969], 'tab': [3132, 3970], 'F,': [3133], 'lysed': [3139], '30': [3141], 'min': [3142], 'ice': [3144], 'ml': [3147], 'lysis': [3150], 'buffer': [3151], '0.5%': [3153], 'Nonidet': [3154], 'P-40,': [3155], '50': [3156], 'mmHepes,': [3157], 'pH': [3158, 3364], '7.3,': [3159], '150': [3160], 'mm': [3161, 3164, 3176, 3180, 3185], 'NaCl,': [3162], 'EDTA,': [3165], 'μg/ml': [3167, 3170, 3173], 'aprotinin,': [3168], 'leupeptin,': [3171], 'pepstatin,': [3174], 'phenylmethylsulfonyl': [3177], 'fluoride,': [3178], '0.1': [3179], 'sodium': [3181], 'orthovanadate,': [3182], 'NaF.': [3186], 'Protein': [3187], '(15': [3189], 'μg)': [3190], 'electrophoresis': [3194], 'SDS-PAGE': [3197], 'gels': [3198], 'transferred': [3200], 'nitrocellulose': [3203], 'membrane.': [3204], 'Antibody-bound': [3205], 'bands': [3207], 'then': [3209, 3373], 'visualized': [3210], 'horseradish': [3212], 'peroxidase-dependent': [3213], 'chemiluminescence': [3214], '(Amersham': [3215, 3381, 3389], 'Biosciences).': [3216], 'Rabbit': [3217], 'anti-NQO1': [3218], 'antibody': [3219, 3248], '(32Shaw': [3223], 'P.M.': [3224], 'Reiss': [3225], 'Adesnik': [3227], 'Nebert': [3229], 'D.W.': [3230], 'Schembri': [3231], 'Eur.': [3235], '195:': [3239], '171-176Crossref': [3240], '(58)': [3243], 'Mouse': [3246], 'monoclonal': [3247], 'β-tubulin': [3250], 'purchased': [3252], 'Santa': [3254], 'Cruz': [3255], 'Biotechnology': [3256], 'One': [3269], '60–70%': [3275], 'confluence': [3276, 3308], '6-well': [3278], 'plates': [3279], 'transfected': [3281, 3316], 'various': [3283, 3392], 'plasmids': [3284, 3320], 'figure': [3288], 'legends': [3289], 'SuperFect': [3291, 3322], 'transfection': [3292, 3471], 'reagent': [3293], '(Qiagen,': [3298], 'Inc).': [3299], '60%': [3307], 'plates.': [3312], 'reagents.': [3323], '24': [3324, 3344], 'after': [3326], 'transfection,': [3327], 'h.': [3345, 3535, 4018, 4106], 'determination': [3347], 'activity,': [3350], 'extracts': [3352], 'rapid': [3358], 'freeze-thaw': [3359], '0.25': [3361], 'm': [3362], 'Tris,': [3363], '8.0.': [3365], 'per': [3370], 'incubated': [3374], 'μCi': [3377], '14C-labeled': [3379], 'Biosciences)': [3382, 3390], 'ofn-butyryl': [3386], 'coenzyme': [3387], 'A': [3388], 'times.': [3393], 'acetylated': [3395], 'forms': [3397], 'extracted': [3399], '2:1': [3402], 'mixture': [3403], '2,6,10,14-tetramethylpentadecane:xylenes': [3405], 'centrifugation': [3409], '(33Kinston': [3410], 'R.E.': [3411], 'Sheen': [3412], 'Ausubel': [3414], 'Current': [3416], 'Prtotocols': [3417], 'Molecular': [3419], 'Biology.': [3420], 'John': [3421], 'Wiley': [3422], '&': [3423], 'Sons,': [3424], 'Inc.,': [3425], 'New': [3426], 'York1995:': [3427], '9.7.1Google': [3428], 'organic': [3431], 'removed': [3434], 'counted': [3436], 'determine': [3438], 'Plasmids': [3441], 'pRL-TK': [3442], 'pRL-SV40': [3444], '(Renilla': [3445], 'luciferase': [3446, 3474, 3480, 3498], 'constitutively': [3447], 'control': [3451], 'thymidine': [3454], 'kinase': [3455], 'SV40': [3457], 'respectively)': [3459], 'co-transfected': [3461], 'all': [3463, 4001], 'normalize': [3469], 'efficiency.': [3472], 'Renilla': [3473, 3497], 'assay': [3482], 'activities': [3492], 'normalized': [3494], 'identify': [3501], 'flow,': [3511], 'constructed': [3513], 'kept': [3519], 'Differentially': [3536], 'library': [3542, 3554, 3574], 'hybridization,': [3547], 'hundred': [3550], 'sequencing.': [3559], 'many': [3564], 'abundant': [3569], 'Analysis': [3580], 'subset': [3586], 'these': [3588, 3613, 3636, 3986], 'revealed': [3605], 'feature.': [3610], 'element(s)': [3622], 'its': [3624], 'known': [3628], 'Table': [3647], 'shows': [3649], 'alignment': [3652, 3723], 'elements': [3659], 'flow-inducible': [3663], 'consensus': [3668], 'sequence,': [3670], 'RTGACNNNGC': [3671], '14Wasserman': [3684], 'observations': [3704, 4020], 'provide': [3705], 'suggestion': [3708], 'AREs': [3711, 3725], 'mediate': [3713], 'cells.Table': [3720], 'IIDNA': [3721], 'regulated': [3729], 'genesGenes': [3730], 'SequencesReferencesHuman': [3731], 'gcagtcaca': [3733], 'GTGAC': [3734, 3765, 3796, 3823, 3880, 3903], 'tea': [3735], 'agaatct25Xie': [3737, 3768], 'ScholarMurine': [3760, 3791, 3877], 'chain)': [3763, 3794], 'cctcc': [3764], 'tca': [3766, 3797, 3824, 3852, 3904], 'tcagc': [3795], 'agaac18Tsuji': [3799], 'ScholarHuman': [3821, 3849, 3901], 'a62Li': [3826, 3854], 'Venkatesan': [3828, 3856], 'M.I.': [3829, 3857], 'Miguel': [3830, 3858], 'Kaplan': [3832, 3860], 'Gujuluva': [3834, 3862], 'Alam': [3836, 3864], 'Nel': [3838, 3866], 'Immunol.': [3841, 3869], '165:': [3843, 3871], '3393-3401Crossref': [3844, 3872], '(257)': [3847, 3875], 'ATGAC': [3851, 3931], 'GST': [3878], 'gctaatg': [3879], 'aaa': [3881], 'aactt15Prestera': [3883], 'γ-glutamylcysteinecagcctcccc': [3902], 'gcttt63Mulcahy': [3906], 'R.T.': [3907], 'Wartman': [3908], 'Bailey': [3910], 'H.H.': [3911], 'J.J.': [3913], '272:': [3918], '7445-7454Abstract': [3919], '(418)': [3927], 'ScholarConsensus': [3929], 'nnnn': [3930], 'nnn': [3932], 'nnn13Jaiswal': [3934], 'Scholar': [3963], 'G': [3964], 'confirm': [3972, 4021], 'our': [3973], 'induces': [3982], 'genes,': [3987], 'evaluated': [3992, 4077], 'RT-PCR.': [3995], 'As': [3996, 4085, 4148, 4174], 'shown': [3997, 4086, 4149], 'Fig.': [3999, 4088, 4151], '1,': [4000], 'induced,': [4006], 'although': [4007], 'varying': [4009], 'degrees,': [4010], 'ARE-containing': [4037], 'cytoprotective': [4038], 'controls.': [4043], 'characterize': [4045], 'expression,': [4057], 'focused': [4059], 'time,': [4069], 'rates,': [4071], 'types': [4073], 'contribution': [4080], 'A,': [4090], 'progressively': [4101, 4118], '12': [4103], '6': [4120], '(Fig.': [4124, 4146], 'B).': [4126], 'remained': [4139], 'constant': [4141], 'throughout': [4142], 'course': [4145], '2).': [4147], '3,': [4152], 'dependent': [4167], 'cultures,': [4178], '∼7-fold.': [4192], 'Incr': [4193]}, 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