Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2051551416', 'doi': 'https://doi.org/10.1093/carcin/16.3.491', 'title': 'The high hepatocarcinogen susceptibility of LEC rats is genetically independent of abnormal copper accumulation in the liver', 'display_name': 'The high hepatocarcinogen susceptibility of LEC rats is genetically independent of abnormal copper accumulation in the liver', 'publication_year': 1995, 'publication_date': '1995-01-01', 'ids': {'openalex': 'https://openalex.org/W2051551416', 'doi': 'https://doi.org/10.1093/carcin/16.3.491', 'mag': '2051551416', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7697803'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/carcin/16.3.491', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S184620562', 'display_name': 'Carcinogenesis', 'issn_l': '0143-3334', 'issn': ['0143-3334', '1460-2180'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109163823', 'display_name': 'Atsuo Hattori', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141882310', 'display_name': 'Sapporo Medical University', 'ror': 'https://ror.org/01h7cca57', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I141882310']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Atsuo Hattori', 'raw_affiliation_strings': ['Department of Pathology, Sapporo Medical University, School of Medicine, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Sapporo Medical University, School of Medicine, Japan.', 'institution_ids': ['https://openalex.org/I141882310']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082232407', 'display_name': 'Masakuni Sawaki', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Masakuni Sawaki', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030695740', 'display_name': 'Katsuhiko Enomoto', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Katsuhiko Enomoto', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005569788', 'display_name': 'Naoto Tsuzuki', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Naoto Tsuzuki', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112302678', 'display_name': 'Hiroshi Isomura', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Isomura', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082685387', 'display_name': 'Takashi Kojima', 'orcid': 'https://orcid.org/0000-0002-2554-8334'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Takashi Kojima', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071175900', 'display_name': 'Yoshihito Kamibayashi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yoshihito Kamibayashi', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111828096', 'display_name': 'Naoki Sugawara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141882310', 'display_name': 'Sapporo Medical University', 'ror': 'https://ror.org/01h7cca57', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I141882310']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Naoki Sugawara', 'raw_affiliation_strings': ['Department of Public Health, Sapporo Medical University School of MedicineS-1, W-17, Chuo-ku, Sapporo 060'], 'affiliations': [{'raw_affiliation_string': 'Department of Public Health, Sapporo Medical University School of MedicineS-1, W-17, Chuo-ku, Sapporo 060', 'institution_ids': ['https://openalex.org/I141882310']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107392063', 'display_name': 'Toshihiro Sugiyama', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I203765153', 'display_name': 'Akita University', 'ror': 'https://ror.org/03hv1ad10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I203765153']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Toshihiro Sugiyama', 'raw_affiliation_strings': ['Department of Biochemistry, Akita University School of MedicineAkita 010, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Akita University School of MedicineAkita 010, Japan', 'institution_ids': ['https://openalex.org/I203765153']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5102399942', 'display_name': 'Michio Mori', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Michio Mori', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4428, 'currency': 'USD', 'value_usd': 4428, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.828, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 12, 'citation_normalized_percentile': {'value': 0.596554, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 79, 'max': 80}, 'biblio': {'volume': '16', 'issue': '3', 'first_page': '491', 'last_page': '494'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10915', 'display_name': 'Trace Elements in Health', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10915', 'display_name': 'Trace Elements in Health', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C544778455', 'wikidata': 'https://www.wikidata.org/wiki/Q753', 'display_name': 'Copper', 'level': 2, 'score': 0.4699469}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3684157}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.35429364}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33596653}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.33206755}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.30936003}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003300', 'descriptor_name': 'Copper', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008114', 'descriptor_name': 'Liver Neoplasms, Experimental', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003300', 'descriptor_name': 'Copper', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003577', 'descriptor_name': 'Cytochrome P-450 Enzyme System', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003577', 'descriptor_name': 'Cytochrome P-450 Enzyme System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015786', 'descriptor_name': 'Cytochromes b5', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015786', 'descriptor_name': 'Cytochromes b5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008114', 'descriptor_name': 'Liver Neoplasms, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008114', 'descriptor_name': 'Liver Neoplasms, Experimental', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011916', 'descriptor_name': 'Rats, Inbred F344', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/carcin/16.3.491', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S184620562', 'display_name': 'Carcinogenesis', 'issn_l': '0143-3334', 'issn': ['0143-3334', '1460-2180'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7697803', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.69, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W657579294', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W1986764834', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'Journal': [0], 'Article': [1, 236], 'The': [2], 'high': [3], 'hepatocarcinogen': [4], 'susceptibility': [5], 'of': [6, 12, 152, 159, 183, 188], 'LEC': [7], 'rats': [8], 'is': [9], 'genetically': [10], 'independent': [11], 'abnormal': [13], 'copper': [14], 'accumulation': [15], 'in': [16], 'the': [17], 'liver': [18], 'Get': [19], 'access': [20], 'Atsuo': [21, 23], 'Hattori,': [22], 'Hattori': [24], '3': [25], '3To': [26], 'whom': [27], 'correspondence': [28], 'should': [29], 'be': [30], 'addressed': [31], 'Search': [32, 49, 66, 83, 100, 117, 134, 165, 192, 209], 'for': [33, 50, 67, 84, 101, 118, 135, 166, 193, 210], 'other': [34, 51, 68, 85, 102, 119, 136, 167, 194, 211], 'works': [35, 52, 69, 86, 103, 120, 137, 168, 195, 212], 'by': [36, 53, 70, 87, 104, 121, 138, 169, 196, 213], 'this': [37, 54, 71, 88, 105, 122, 139, 170, 197, 214], 'author': [38, 55, 72, 89, 106, 123, 140, 171, 198, 215], 'on:': [39, 56, 73, 90, 107, 124, 141, 172, 199, 216], 'Oxford': [40, 57, 74, 91, 108, 125, 142, 173, 200, 217], 'Academic': [41, 58, 75, 92, 109, 126, 143, 174, 201, 218], 'PubMed': [42, 59, 76, 93, 110, 127, 144, 175, 202, 219], 'Google': [43, 60, 77, 94, 111, 128, 145, 176, 203, 220], 'Scholar': [44, 61, 78, 95, 112, 129, 146, 177, 204, 221], 'Masakuni': [45, 47], 'Sawaki,': [46], 'Sawaki': [48], 'Katsuhiko': [62, 64], 'Enomoto,': [63], 'Enomoto': [65], 'Naoto': [79, 81], 'Tsuzuki,': [80], 'Tsuzuki': [82], 'Hiroshi': [96, 98], 'Isomura,': [97], 'Isomura': [99], 'Takashi': [113, 115], 'Kojima,': [114], 'Kojima': [116], 'Yoshihito': [130, 132], 'Kamibayashi,': [131], 'Kamibayashi': [133], 'Naoki': [147, 149], 'Sugawara,': [148], 'Sugawara': [150], '1Department': [151], 'Public': [153], 'Health,': [154], 'Sapporo': [155, 163], 'Medical': [156], 'University': [157, 186], 'School': [158, 187], 'MedicineS-1,': [160], 'W-17,': [161], 'Chuo-ku,': [162], '060': [164], 'Toshihiro': [178, 180], 'Sugiyama,': [179], 'Sugiyama': [181], '2Department': [182], 'Biochemistry,': [184], 'Akita': [185], 'MedicineAkita': [189], '010,': [190], 'Japan': [191], 'Michio': [205, 207], 'Mori': [206, 208], 'Carcinogenesis,': [222], 'Volume': [223], '16,': [224], 'Issue': [225], '3,': [226], 'March': [227, 234, 253], '1995,': [228], 'Pages': [229], '491–494,': [230], 'https://doi.org/10.1093/carcin/16.3.491': [231], 'Published:': [232, 251], '01': [233, 252], '1995': [235, 254], 'history': [237], 'Received:': [238], '26': [239], 'August': [240], '1994': [241, 246, 250], 'Revision': [242], 'received:': [243], '29': [244], 'November': [245], 'Accepted:': [247], '06': [248], 'December': [249]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2051551416', 'counts_by_year': [], 'updated_date': '2024-12-12T22:23:24.739688', 'created_date': '2016-06-24'}