Detection of<i>BRAF</i><sup>V600E</sup>Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing

Name: Work Video:
Duration: 3 min 30 s
Dongjun Jeong; Yujun Jeong; Sungche Lee; Hyeran Lee; Wanju Lee; Hyungjoo Kim; Doosan Park; Soyoung Park; Wenxia Mu; Hyun‐Deuk Cho; Mee‐Hye Oh; Sungsoo Lee; Seung‐Ha Yang; Chang‐Jin Kim
{'id': 'https://openalex.org/W2051050264', 'doi': 'https://doi.org/10.4132/koreanjpathol.2012.46.1.61', 'title': 'Detection of<i>BRAF</i><sup>V600E</sup>Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing', 'display_name': 'Detection of<i>BRAF</i><sup>V600E</sup>Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing', 'publication_year': 2012, 'publication_date': '2012-01-01', 'ids': {'openalex': 'https://openalex.org/W2051050264', 'doi': 'https://doi.org/10.4132/koreanjpathol.2012.46.1.61', 'mag': '2051050264', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23109980', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3479705'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4132/koreanjpathol.2012.46.1.61', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S130264985', 'display_name': 'The Korean Journal of Pathology', 'issn_l': '1738-1843', 'issn': ['1738-1843', '2092-8920'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319411', 'host_organization_name': 'Korean Society of Pathologists & the Korean Society for Cytopathology', 'host_organization_lineage': ['https://openalex.org/P4310319411'], 'host_organization_lineage_names': ['Korean Society of Pathologists & the Korean Society for Cytopathology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.4132/koreanjpathol.2012.46.1.61', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5036729023', 'display_name': 'Dongjun Jeong', 'orcid': 'https://orcid.org/0000-0001-8180-5668'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Dongjun Jeong', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042904119', 'display_name': 'Yujun Jeong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yujun Jeong', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069314807', 'display_name': 'Sungche Lee', 'orcid': 'https://orcid.org/0000-0001-5324-7777'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sungche Lee', 'raw_affiliation_strings': ['Senior Undergraduate, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Senior Undergraduate, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102973370', 'display_name': 'Hyeran Lee', 'orcid': 'https://orcid.org/0000-0003-0722-419X'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyeran Lee', 'raw_affiliation_strings': ['Senior Undergraduate, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Senior Undergraduate, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057747088', 'display_name': 'Wanju Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Wanju Lee', 'raw_affiliation_strings': ['College of Medical Sciences, Soonchunhyang University, Asan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'College of Medical Sciences, Soonchunhyang University, Asan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101794541', 'display_name': 'Hyungjoo Kim', 'orcid': 'https://orcid.org/0000-0003-1627-4797'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyungjoo Kim', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075230519', 'display_name': 'Doosan Park', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Doosan Park', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100417986', 'display_name': 'Soyoung Park', 'orcid': 'https://orcid.org/0000-0002-6144-7813'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Soyoung Park', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077775423', 'display_name': 'Wenxia Mu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Wenxia Mu', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026462102', 'display_name': 'Hyun‐Deuk Cho', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyun-Deuk Cho', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025574564', 'display_name': 'Mee‐Hye Oh', 'orcid': 'https://orcid.org/0000-0002-2395-1752'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Mee-Hye Oh', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033375010', 'display_name': 'Sungsoo Lee', 'orcid': 'https://orcid.org/0000-0001-8998-9510'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sung Soo Lee', 'raw_affiliation_strings': ['Department of Preventive Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Preventive Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022749998', 'display_name': 'Seung‐Ha Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Seung-Ha Yang', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101454525', 'display_name': 'Chang‐Jin Kim', 'orcid': 'https://orcid.org/0000-0002-9440-4721'}, 'institutions': [{'id': 'https://openalex.org/I24541011', 'display_name': 'Soonchunhyang University', 'ror': 'https://ror.org/03qjsrb10', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I24541011']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Chang-Jin Kim', 'raw_affiliation_strings': ['Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Soonchunhyang University College of Medicine, Cheonan, Korea.', 'institution_ids': ['https://openalex.org/I24541011']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.315, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.935912, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '46', 'issue': '1', 'first_page': '61', 'last_page': '61'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10329', 'display_name': 'Thyroid Cancer Diagnosis and Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10329', 'display_name': 'Thyroid Cancer Diagnosis and Treatment', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10583', 'display_name': 'Cancer-related Molecular Pathways', 'score': 0.956, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/v600e', 'display_name': 'V600E', 'score': 0.75090057}, {'id': 'https://openalex.org/keywords/peptide-nucleic-acid', 'display_name': 'Peptide nucleic acid', 'score': 0.5068677}, {'id': 'https://openalex.org/keywords/thyroid-nodules', 'display_name': 'Thyroid Nodules', 'score': 0.41058296}], 'concepts': [{'id': 'https://openalex.org/C2993294228', 'wikidata': 'https://www.wikidata.org/wiki/Q13632630', 'display_name': 'Thyroid carcinoma', 'level': 3, 'score': 0.7631618}, {'id': 'https://openalex.org/C2776470698', 'wikidata': 'https://www.wikidata.org/wiki/Q21851559', 'display_name': 'V600E', 'level': 4, 'score': 0.75090057}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.63705724}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.59677905}, {'id': 'https://openalex.org/C526584372', 'wikidata': 'https://www.wikidata.org/wiki/Q16399', 'display_name': 'Thyroid', 'level': 2, 'score': 0.5731836}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.5483296}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5113601}, {'id': 'https://openalex.org/C2777343594', 'wikidata': 'https://www.wikidata.org/wiki/Q412152', 'display_name': 'Peptide nucleic acid', 'level': 3, 'score': 0.5068677}, {'id': 'https://openalex.org/C176944494', 'wikidata': 'https://www.wikidata.org/wiki/Q1415380', 'display_name': 'Point mutation', 'level': 4, 'score': 0.45351806}, {'id': 'https://openalex.org/C2779399171', 'wikidata': 'https://www.wikidata.org/wiki/Q1483951', 'display_name': 'Malignancy', 'level': 2, 'score': 0.4477772}, {'id': 'https://openalex.org/C2779022025', 'wikidata': 'https://www.wikidata.org/wiki/Q53829', 'display_name': 'Thyroid nodules', 'level': 3, 'score': 0.41058296}, {'id': 'https://openalex.org/C24107716', 'wikidata': 'https://www.wikidata.org/wiki/Q123619', 'display_name': 'Nucleic acid', 'level': 2, 'score': 0.31527668}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.29711354}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.26020053}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.25896}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.10129526}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.4132/koreanjpathol.2012.46.1.61', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S130264985', 'display_name': 'The Korean Journal of Pathology', 'issn_l': '1738-1843', 'issn': ['1738-1843', '2092-8920'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319411', 'host_organization_name': 'Korean Society of Pathologists & the Korean Society for Cytopathology', 'host_organization_lineage': ['https://openalex.org/P4310319411'], 'host_organization_lineage_names': ['Korean Society of Pathologists & the Korean Society for Cytopathology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3479705', 'pdf_url': 'https://europepmc.org/articles/pmc3479705?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479705', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23109980', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4132/koreanjpathol.2012.46.1.61', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S130264985', 'display_name': 'The Korean Journal of Pathology', 'issn_l': '1738-1843', 'issn': ['1738-1843', '2092-8920'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319411', 'host_organization_name': 'Korean Society of Pathologists & the Korean Society for Cytopathology', 'host_organization_lineage': ['https://openalex.org/P4310319411'], 'host_organization_lineage_names': ['Korean Society of Pathologists & the Korean Society for Cytopathology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.57, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1539993673', 'https://openalex.org/W1562442816', 'https://openalex.org/W1755477811', 'https://openalex.org/W1800883185', 'https://openalex.org/W1842332833', 'https://openalex.org/W1933537883', 'https://openalex.org/W1967511948', 'https://openalex.org/W1967911512', 'https://openalex.org/W1976593786', 'https://openalex.org/W2009344449', 'https://openalex.org/W2023914805', 'https://openalex.org/W2025577953', 'https://openalex.org/W2030067547', 'https://openalex.org/W2042213687', 'https://openalex.org/W2062170395', 'https://openalex.org/W2066467575', 'https://openalex.org/W2074435495', 'https://openalex.org/W2078212012', 'https://openalex.org/W2082047081', 'https://openalex.org/W2084548165', 'https://openalex.org/W2090880516', 'https://openalex.org/W2091910297', 'https://openalex.org/W2099938880', 'https://openalex.org/W2100409527', 'https://openalex.org/W2103255787', 'https://openalex.org/W2104658211', 'https://openalex.org/W2140777372', 'https://openalex.org/W2153480461', 'https://openalex.org/W2171003891', 'https://openalex.org/W2171379946', 'https://openalex.org/W4231372799'], 'related_works': ['https://openalex.org/W4321252293', 'https://openalex.org/W3009148087', 'https://openalex.org/W2997507453', 'https://openalex.org/W2902514062', 'https://openalex.org/W2586300812', 'https://openalex.org/W2104570330', 'https://openalex.org/W2083786241', 'https://openalex.org/W2075234005', 'https://openalex.org/W2051050264', 'https://openalex.org/W1995219003'], 'abstract_inverted_index': {'Papillary': [0], 'thyroid': [1, 6, 60, 74, 126], 'carcinoma': [2], '(PTC)': [3], 'of': [4, 15, 20, 33, 46, 58, 88, 97, 102, 110, 163], 'the': [5, 8, 31, 44, 89, 100, 103, 113, 129, 161, 164], 'is': [7, 157], 'most': [9], 'common': [10], 'endocrine': [11], 'malignancy.': [12], 'High': [13], 'prevalence': [14], 'an': [16], 'activating': [17], 'point': [18], 'mutation': [19, 48, 80, 132, 166], 'BRAF': [21], 'gene,': [22], 'BRAF(V600E),': [23], 'has': [24], 'been': [25], 'reported': [26], 'in': [27, 49, 51, 167, 169], 'PTC.': [28], 'We': [29], 'assessed': [30], 'efficiency': [32], 'peptide': [34], 'nucleic': [35], 'acid': [36], 'clamp': [37], 'real-time': [38], 'polymerase': [39], 'chain': [40], 'reaction': [41], '(PNAcqPCR)': [42], 'for': [43, 78, 99, 160], 'detection': [45, 101, 162], 'BRAF(V600E)': [47, 79, 104, 114, 165], 'PTC': [50], 'comparison': [52], 'with': [53, 135, 152], 'direct': [54], 'sequencing': [55], '(DS).A': [56], 'total': [57], '265': [59], 'lesions': [61, 70, 122], 'including': [62], '200': [63], 'PTCs,': [64], '5': [65, 117], 'follicular': [66, 118], 'carcinomas,': [67, 119], '60': [68], 'benign': [69, 121], 'and': [71, 83, 86, 123, 147], '10': [72, 124], 'normal': [73, 125], 'tissues': [75, 127], 'were': [76, 92], 'tested': [77], 'by': [81], 'PNAcqPCR': [82, 90, 155], 'DS.The': [84], 'sensitivity': [85], 'accuracy': [87], 'method': [91, 156], 'both': [93], 'higher': [94], 'than': [95], 'those': [96], 'DS': [98], 'mutation.': [105, 130], 'In': [106], 'clinical': [107, 137, 171], 'samples,': [108], '89%': [109], 'PTCs': [111, 168], 'harbored': [112], 'mutation,': [115], 'whereas': [116], '50': [120], 'lacked': [128], 'The': [131], 'was': [133], 'associated': [134], 'aggressive': [136], 'behaviors': [138], 'as': [139], 'extrathyroid': [140], 'invasion': [141], '(p=0.015),': [142], 'lymph': [143], 'node': [144], 'metastasis': [145], '(p=0.002)': [146], 'multiple': [148], 'tumor': [149], 'numbers': [150], '(p=0.016)': [151], 'statistical': [153], 'significance.The': [154], 'efficiently': [158], 'applicable': [159], 'a': [170], 'setting.': [172]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2051050264', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-10T05:38:34.762549', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
