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485, 488, 2943, 2969], 'protein': [4, 166, 486, 575, 1186, 1318, 2957, 3299, 3737], 'signaling': [5, 16, 167, 178, 344, 549], '(RGS)': [6, 168], 'domain': [7, 45, 95, 169, 207, 257, 1108, 1116, 1121, 1238, 1327, 1347, 1813, 2355, 2522, 2602, 2674, 2756, 2794, 2897, 2917, 2932, 3185, 3359], 'Axin,': [9, 144, 171, 306, 324], 'a': [10, 19, 150, 172, 181, 312, 327, 338, 383, 573, 765, 1107, 1185, 1230, 1243, 1247, 1301, 1317, 2013, 2118, 2238, 2361, 2526, 2633, 2847, 2952, 2960, 3063, 3091, 3150, 3241, 3441, 3454], 'negative': [11, 173, 339], 'regulator': [12, 174, 340], 'the': [14, 49, 52, 61, 77, 84, 87, 93, 108, 155, 158, 176, 211, 214, 223, 239, 246, 249, 255, 270, 317, 320, 330, 342, 547, 552, 641, 650, 697, 708, 720, 725, 753, 757, 773, 900, 920, 926, 931, 976, 982, 987, 991, 1058, 1062, 1065, 1075, 1084, 1091, 1119, 1190, 1236, 1254, 1325, 1334, 1345, 1353, 1356, 1365, 1413, 1476, 1559, 1589, 1616, 1793, 1797, 1802, 1808, 1811, 1828, 1855, 1860, 1872, 1914, 1919, 1923, 1928, 1944, 1973, 1978, 1983, 1987, 2000, 2063, 2080, 2087, 2103, 2107, 2112, 2256, 2305, 2315, 2332, 2347, 2353, 2461, 2520, 2529, 2578, 2600, 2661, 2672, 2680, 2683, 2690, 2700, 2709, 2754, 2761, 2766, 2770, 2773, 2786, 2792, 2799, 2882, 2886, 2895, 2915, 2930, 2935, 2939, 2948, 2955, 2965, 3010, 3051, 3084, 3104, 3117, 3123, 3131, 3158, 3172, 3183, 3196, 3216, 3250, 3294, 3298, 3306, 3323, 3327, 3357, 3363, 3374, 3378, 3390, 3411, 3415, 3469, 3483, 3486, 3524, 3531, 3560, 3568, 3605, 3613, 3652, 3655, 3667, 3673, 3689, 3721, 3867, 3879], 'Wnt': [15, 177, 343, 548], 'pathway,': [17, 179], 'made': [18, 180], 'complex': [20, 182, 2239, 2362, 2527, 2849], 'with': [21, 35, 48, 58, 103, 117, 125, 183, 197, 210, 220, 265, 279, 287, 707, 937, 986, 1069, 1319, 1338, 1352, 1371, 1584, 1612, 1627, 1631, 1640, 1659, 1662, 1667, 1683, 1777, 1792, 1801, 1816, 1827, 1851, 1859, 1877, 1918, 1932, 1940, 1977, 2019, 2023, 2067, 2092, 2102, 2111, 2117, 2240, 2255, 2260, 2289, 2342, 2363, 2374, 2454, 2460, 2511, 2528, 2539, 2595, 2607, 2679, 2694, 2760, 2785, 2798, 2909, 2934, 3009, 3135, 3162, 3171, 3213, 3410, 3440, 3573, 3619, 3686], 'full-length': [22, 184, 2505, 3223], 'adenomatous': [23, 185, 472, 477], 'polyposis': [24, 186, 473], 'coli': [25, 187, 1473], '(APC)': [26, 188], 'in': [27, 38, 112, 154, 189, 200, 274, 316, 447, 716, 899, 1090, 1234, 1602, 1820, 1885, 1943, 1954, 2250, 2304, 2314, 2331, 2366, 2392, 2446, 2534, 2581, 2632, 2802, 2815, 2894, 2914, 3062, 3090, 3149, 3175, 3396, 3535, 3617, 3629, 3661, 3717, 3728, 3824, 3831], 'COS,': [28, 190, 1835, 2367], '293,': [29, 191, 1836, 2368], 'and': [30, 99, 130, 132, 147, 192, 261, 292, 294, 309, 389, 392, 453, 460, 612, 771, 889, 978, 1083, 1088, 1102, 1114, 1198, 1250, 1310, 1361, 1407, 1409, 1423, 1425, 1449, 1456, 1465, 1482, 1493, 1500, 1512, 1528, 1571, 1588, 1615, 1629, 1642, 1644, 1665, 1685, 1771, 1804, 1839, 1854, 1883, 1896, 1913, 1972, 1990, 2025, 2069, 2096, 2106, 2115, 2294, 2308, 2317, 2369, 2390, 2394, 2398, 2448, 2506, 2572, 2589, 2660, 2705, 2718, 2739, 2769, 2772, 2804, 2852, 3048, 3060, 3066, 3128, 3142, 3201, 3234, 3326, 3377, 3423, 3426, 3482, 3522, 3631, 3659, 3730, 3826, 3834, 3854, 3860], 'L': [31, 193, 1421, 2370], 'cells': [32, 194, 936, 1427, 1678, 1841, 2009, 2064, 2081, 2252, 2371, 2450, 2591, 3398, 3419], 'but': [33, 56, 195, 218, 609, 806, 929, 1192, 2312, 2326, 2723, 2746, 2790, 3189, 3354], 'not': [34, 57, 196, 219, 562, 606, 1072, 1096, 1193, 2313, 2327, 2452, 2593, 2651, 2747, 2758, 2791, 2912, 3080, 3155, 3190, 3204, 3211, 3332, 3355, 3370, 3434, 3684], 'truncated': [36, 198, 903, 2385, 2401, 2507], 'APC': [37, 199, 794, 895, 939, 1059, 1068, 1080, 1087, 1360, 1417, 1579, 1590, 1817, 1931, 2166, 2241, 2301, 2325, 2339, 2365, 2383, 2404, 2444, 2508, 2533, 2579, 2613, 2693, 2764, 2800, 3007, 3049, 3127, 3202, 3219, 3233, 3248, 3289, 3366, 3624, 3656, 3681, 3694, 3736, 3825], 'SW480': [39, 201, 1424, 2393, 2447, 2588, 2803], 'or': [40, 202, 1951, 2022, 2085], 'DLD-1': [41, 203, 1426, 1840, 2395, 2449, 2590, 2805], 'cells.': [42, 114, 204, 276, 2536, 2806], 'RGS': [44, 94, 206, 256, 1120, 1179, 1237, 1326, 1346, 1560, 1812, 2348, 2354, 2521, 2601, 2673, 2755, 2793, 2810, 2887, 2896, 2916, 2931, 2956, 3184, 3358], 'directly': [46, 123, 208, 285, 603, 1350, 1402, 2130, 2163, 2605, 2677, 2976], 'interacted': [47, 102, 209, 264], 'region': [50, 78, 85, 212, 240, 247, 1354, 2681, 2762, 3296, 3350], 'containing': [51, 60, 79, 86, 213, 222, 241, 248, 1355, 1578, 2682, 2765, 3322, 3670], '20-amino': [53, 81, 215, 243], 'acid': [54, 63, 82, 216, 225, 244, 799], 'repeats': [55, 64, 90, 217, 226, 252, 801, 813, 928, 1358, 2659, 2685, 2768, 2983, 3012, 3325], 'that': [59, 121, 133, 143, 221, 283, 295, 305, 385, 693, 710, 751, 897, 1109, 1187, 1228, 1251, 1297, 1311, 1344, 1362, 1400, 1410, 2128, 2161, 2382, 2399, 2519, 2577, 2671, 2788, 2880, 2905, 2929, 2951, 2974, 3174, 3247, 3348, 3462, 3518, 3523, 3576, 3610, 3679, 3711, 3733], '15-amino': [62, 224, 798], 'APC,': [66, 145, 228, 307, 471, 762, 1405, 2570, 2608, 3664], 'although': [67, 229, 3103, 3195], 'both': [68, 230, 2504, 2737, 3140], 'regions': [69, 231], 'are': [70, 232, 705, 814, 1095, 2783, 2891, 2911, 2947, 3169, 3222, 3649, 3713, 3811], 'known': [71, 233, 2381], 'to': [72, 74, 92, 234, 236, 254, 605, 769, 772, 816, 819, 975, 1100, 1112, 1189, 1304, 1316, 1332, 1404, 1475, 2132, 2165, 2406, 2625, 2644, 2653, 2721, 2726, 2736, 2744, 2748, 2779, 2821, 2978, 3058, 3072, 3088, 3139, 3147, 3180, 3187, 3191, 3207, 3218, 3293, 3352, 3356, 3367, 3380, 3467, 3651, 3700, 3703, 3705, 3816, 3822, 3865], 'bind': [73, 235, 817, 2652, 3206, 3704], 'β-catenin.': [75, 161, 237, 323, 700, 1078, 1368, 1416, 2243, 2780, 3055, 3472], 'In': [76, 238, 887, 1098], 'seven': [80, 242, 804, 2629], 'repeats,': [83, 245, 2631, 2704, 2713, 2776], 'latter': [88, 250, 2710], 'five': [89, 251], 'bound': [91, 253, 2624, 2720, 2725, 2735, 2743, 3057, 3146], 'Axin.': [97, 259, 3706], 'Axin': [98, 106, 122, 260, 268, 284, 446, 456, 537, 557, 570, 711, 1089, 1233, 1252, 1308, 1321, 1401, 3381, 3838], 'β-catenin': [100, 111, 131, 148, 262, 273, 293, 310, 617, 644, 653, 723, 760, 820, 945, 973, 985, 1070, 1082, 1094, 1483, 1670, 1805, 1933, 2133, 2162, 2286, 2328, 2337, 2408, 2789, 3015, 3134, 3141, 3177, 3209, 3253, 3334, 3353, 3368, 3375, 3490, 3519, 3527, 3536, 3563, 3582, 3616, 3725, 3820, 3827], 'simultaneously': [101, 263, 3205], 'APC.': [104, 266, 2364, 2687, 3620], 'Furthermore,': [105, 267, 2733, 3114, 3225], 'stimulated': [107, 269], 'degradation': [109, 271, 698, 1092, 3561], 'COS': [113, 275, 1677, 2008, 2251, 3397, 3418], 'Taken': [115, 277, 1369, 2537, 3193, 3571], 'together': [116, 278, 1370, 2538, 3572], 'our': [118, 280, 690, 1372, 2261, 2540, 3574], 'recent': [119, 281, 1373, 2262], 'observations': [120, 282, 1374, 2263, 2463, 2541, 2787, 3575], 'interacts': [124, 286, 1351, 2606, 2678, 2933, 3008], 'glycogen': [126, 288, 468], 'synthase': [127, 289, 469], 'kinase-3β': [128, 290], '(GSK-3β)': [129, 291], 'it': [134, 296, 1312, 1411, 2157, 2926, 3153], 'promotes': [135, 297, 613, 3578], 'GSK-3β-dependent': [136, 298, 614, 3579], 'phosphorylation': [137, 299, 615, 642, 754, 3477, 3487, 3533, 3580, 3722], 'β-catenin,': [139, 301, 611, 1406, 2571, 3129, 3208, 3235, 3393, 3475], 'these': [140, 302, 1397, 2400, 3236, 3647, 3680], 'results': [141, 303, 691, 1295, 1398, 2517, 2669, 2782, 2946, 3168, 3173, 3346, 3460, 3607, 3677], 'suggest': [142, 304, 692, 2518, 3609], 'GSK-3β,': [146, 308, 467, 602, 756], 'make': [149, 311, 2906, 3240], 'tetrameric': [151, 313], 'complex,': [152, 314], 'resulting': [153, 315], 'regulation': [156, 318], 'stabilization': [159, 321, 1414, 3391], 'which': [325, 556, 763, 1235, 1320, 1624, 2627, 2655, 2698, 2707, 2777, 2980, 3121, 3137, 3300, 3665], 'is': [326, 382, 599, 647, 764, 1071, 1110, 1117, 1239, 2380, 2384, 2575, 2927, 3369, 3480, 3520, 3528, 3537], 'product': [328], 'mouse': [331], 'Fused': [332, 381], 'locus,': [333], 'has': [334, 561, 748, 1106, 1180, 1225, 2158, 2565, 2812, 2854, 2959, 3228, 3244, 3464, 3514, 3708], 'been': [335, 563, 749, 1181, 1226, 2159, 2813, 2855, 3245, 3515, 3627, 3709], 'identified': [336, 568, 1183, 2814], 'as': [337, 572, 1184, 1242, 1532, 1690, 2035, 2587, 2616, 3428], 'pathway': [345], '(1Zeng': [346, 502, 1122, 1259], 'L.': [347, 503, 847, 1007, 1123, 1260, 2193, 2490], 'Fagotto': [348, 504, 730, 1124, 1261], 'F.': [349, 366, 505, 522, 731, 1125, 1142, 1262, 1279], 'Zhang': [350, 506, 1126, 1263], 'T.': [351, 507, 1127, 1264, 1433, 1713, 3846], 'Hsu': [352, 508, 1128, 1265], 'W.': [353, 509, 1013, 1129, 1266], 'Vasicek': [354, 510, 1130, 1267], 'T.J.': [355, 511, 1131, 1268], 'Perry': [356, 512, 1132, 1269], 'III': [357, 513, 1133, 1270], 'W.L.': [358, 514, 1134, 1271], 'Lee': [359, 515, 1135, 1272], 'J.J.': [360, 516, 1136, 1273], 'Tilghman': [361, 517, 1137, 1274], 'S.M.': [362, 518, 1138, 1275], 'Gumbiner': [363, 519, 734, 1139, 1276], 'B.M.': [364, 520, 735, 1140, 1277], 'Costantini': [365, 521, 1141, 1278], 'Cell.': [367, 523, 1043, 1143, 1280, 2865], '1997;': [368, 524, 785, 910, 1144, 1211, 1281, 1757, 2414, 2830, 2866, 3259, 3315, 3340, 3551, 3639, 3757, 3780, 3801], '90:': [369, 525, 1145, 1282], '181-192Abstract': [370, 526, 1146, 1283], 'Full': [371, 373, 527, 529, 877, 879, 1047, 1049, 1147, 1149, 1214, 1216, 1284, 1286, 1702, 1704, 1730, 1732, 1760, 1762, 2223, 2225, 2833, 2835, 2869, 2871, 3032, 3034], 'Text': [372, 374, 528, 530, 878, 880, 1048, 1050, 1148, 1150, 1215, 1217, 1285, 1287, 1703, 1705, 1731, 1733, 1761, 1763, 2224, 2226, 2834, 2836, 2870, 2872, 3033, 3035], 'PDF': [375, 531, 881, 1051, 1151, 1218, 1288, 1706, 1734, 1764, 2227, 2837, 2873, 3036], 'PubMed': [376, 406, 417, 435, 532, 593, 635, 663, 685, 742, 841, 856, 882, 966, 1018, 1052, 1152, 1174, 1219, 1289, 1392, 1551, 1707, 1735, 1765, 2057, 2151, 2187, 2202, 2228, 2281, 2438, 2484, 2499, 2559, 2838, 2874, 3002, 3037, 3283, 3508, 3554, 3600, 3760, 3783, 3804], 'Scopus': [377, 418, 436, 533, 594, 636, 664, 686, 743, 842, 857, 883, 967, 1019, 1053, 1153, 1175, 1220, 1290, 1393, 1552, 1708, 1736, 1766, 2058, 2152, 2188, 2203, 2229, 2282, 2439, 2485, 2500, 2560, 2839, 2875, 3003, 3038, 3284, 3509, 3555, 3601, 3761, 3784, 3805], '(793)': [378, 534, 1154, 1291], 'Google': [379, 407, 420, 438, 535, 596, 638, 666, 688, 745, 788, 844, 859, 885, 913, 969, 1021, 1055, 1155, 1177, 1222, 1292, 1395, 1554, 1710, 1738, 1768, 2060, 2154, 2190, 2205, 2231, 2284, 2417, 2441, 2487, 2502, 2562, 2841, 2877, 3005, 3040, 3262, 3286, 3318, 3343, 3511, 3557, 3603, 3642, 3763, 3786, 3807], 'Scholar).': [380, 439, 597, 639, 746, 789, 886, 914, 970, 1056, 1178, 1223, 1293, 1555, 1769, 2061, 2155, 2442, 2842, 2878, 3006, 3041, 3287, 3319, 3344, 3512, 3558, 3643, 3808], 'mutation': [384], 'causes': [386], 'dominant': [387], 'skeletal': [388], 'neurological': [390], 'defects': [391, 396], 'recessive': [393], 'lethal': [394], 'embryonic': [395], 'including': [397, 923], 'neuroectodermal': [398], 'abnormalities': [399], '(2Reed': [400], 'S.C.': [401], 'Genetics.': [402], '1937;': [403], '22:': [404], '1-13Crossref': [405], 'Scholar,': [408, 421, 667, 845, 860, 1022, 1156, 1711, 1739, 2191, 2206, 2488, 3764, 3787], '3Gluecksohn-Schoenheimer': [409], 'S.': [410, 577, 579, 585, 619, 621, 627, 834, 868, 947, 961, 1034, 1158, 1160, 1166, 1376, 1378, 1384, 1535, 1537, 1543, 1715, 1717, 1745, 2038, 2052, 2135, 2137, 2143, 2180, 2214, 2265, 2267, 2273, 2419, 2433, 2477, 2543, 2545, 2551, 2986, 2988, 2994, 3023, 3264, 3278, 3584, 3586, 3592], 'J.': [411, 589, 631, 736, 871, 1000, 1032, 1038, 1170, 1207, 1208, 1388, 1547, 1696, 1724, 1754, 2147, 2217, 2277, 2555, 2826, 2827, 2998, 3026, 3544, 3550, 3596], 'Exp.': [412], 'Zool.': [413], '1949;': [414], '110:': [415], '47-76Crossref': [416], '(73)': [419], '4Jacobs-Cohen': [422], 'R.J.': [423], 'Spiegelman': [424], 'M.': [425, 671, 1005, 1024, 1028, 1030, 1719, 1743, 1749, 3494, 3793], 'Cookingham': [426], 'J.C.': [427], 'Bennett': [428], 'D.': [429, 677, 1009, 3500, 3746], 'Genet.': [430], 'Res.': [431], '1984;': [432], '43:': [433], '43-50Crossref': [434], '(33)': [437], 'Because': [440, 640, 1057, 2156, 2344], 'dorsal': [441, 713], 'injection': [442], 'wild': [444], 'type': [445], 'Xenopus': [448, 717], 'embryos': [449], 'blocks': [450, 1253], 'axis': [451, 500, 543, 559, 714, 726, 1249], 'formation': [452, 544, 560, 715], 'coinjection': [454], 'inhibits': [457, 712], 'Wnt8-,': [458], 'Dsh-,': [459], 'kinase-negative': [461], 'GSK-3β': [462, 608, 646, 1408, 3479, 3532, 3727], '1The': [463], 'abbreviations': [464], 'used': [465], 'are:': [466], 'kinase-3β;': [470], 'coli;': [474], 'FAP,': [475], 'familial': [476], 'polyposis;': [478], 'aa,': [479], 'amino': [480, 2387, 2923], 'acid(s);': [481], 'RGS,': [482, 1113], 'signaling;': [487], 'protein,': [489], 'GTP-binding': [490], 'protein;': [491, 496], 'GST,': [492], 'glutathioneS-transferase;': [493], 'MBP,': [494], 'maltose-binding': [495], 'HA,': [497], 'hemagglutinin.': [498], '-induced': [499], 'duplication': [501, 727], 'Scholar),': [536, 689, 1396, 2232, 2285, 2503, 2563, 3604], 'could': [538, 3239, 3564], 'exert': [539], 'its': [540, 1772, 3476, 3701], 'effects': [541], 'on': [542, 1871, 1927, 2012, 3054, 3130, 3837], 'by': [545, 555, 601, 645, 755, 803, 1336, 1567, 1911, 1969, 1996, 3430, 3478, 3567], 'inhibiting': [546], 'pathway.': [550, 3570], 'However,': [551, 2648, 2900], 'molecular': [553], 'mechanism': [554, 1303], 'regulates': [558, 1412, 3389], 'shown.': [564], 'We': [565, 2124, 2971, 3843, 3863], 'have': [566, 1329, 2125, 2972, 3626, 3734], 'recently': [567, 2126, 3517], 'rat': [569], '(rAxin)': [571], 'GSK-3β-interacting': [574], '(5Ikeda': [576, 618, 1375, 1534, 2134, 2264, 2542, 2985, 3583], 'Kishida': [578, 620, 1159, 1377, 1536, 1714, 1744, 2136, 2266, 2544, 2987, 3585], 'Yamamoto': [580, 622, 1161, 1379, 1538, 2138, 2268, 2546, 2989, 3587], 'H.': [581, 583, 623, 625, 1042, 1162, 1164, 1380, 1382, 1539, 1541, 1741, 2139, 2141, 2269, 2271, 2547, 2549, 2990, 2992, 3540, 3588, 3590, 3755, 3774], 'Murai': [582, 624, 1163, 1381, 1540, 2140, 2270, 2548, 2991, 3589], 'Koyama': [584, 626, 1165, 1383, 1542, 1716, 2142, 2272, 2550, 2993, 3591], 'Kikuchi': [586, 628, 1167, 1385, 1544, 1722, 1752, 2144, 2274, 2552, 2995, 3593], 'A.': [587, 629, 962, 1168, 1386, 1447, 1545, 1693, 1723, 1753, 2053, 2145, 2275, 2434, 2553, 2996, 3279, 3542, 3546, 3594, 3850], 'EMBO': [588, 630, 1169, 1387, 1546, 2146, 2276, 2554, 2997, 3549, 3595], '1998;': [590, 632, 1171, 1389, 1548, 2148, 2278, 2556, 2999, 3597], '17:': [591, 633, 1172, 1390, 1549, 2149, 2279, 2557, 3000, 3598], '1371-1384Crossref': [592, 634, 1173, 1391, 1550, 2150, 2280, 2558, 3001, 3599], '(1101)': [595, 637, 1176, 1394, 1553, 2153, 2283, 2561, 3004, 3602], 'rAxin': [598, 694, 704, 1105, 1349, 1363, 1617, 1770, 1815, 1926, 2129, 2236, 2524, 2564, 2604, 2676, 2695, 2796, 2919, 3047, 3200, 3214, 3227, 3388, 3463, 3577, 3611], 'phosphorylated': [600], 'binds': [604, 1188, 1403, 2131, 2164, 2778, 2977, 3138, 3186, 3351], 'only': [607], 'also': [610, 3099], 'essential': [648], 'for': [649, 1074, 1314, 1842, 1900, 1960, 2073, 2569, 2921, 3126, 3215, 3232, 3372, 3726, 3857, 3870, 3878], 'down-regulation': [651, 758, 1076, 1366, 3470, 3614], '(6Miller': [654], 'J.R.': [655, 673, 3496], 'Moon': [656, 678, 3501], 'R.T.': [657, 679, 3502], 'Genes': [658, 680, 3503], 'Dev.': [659, 681, 3504], '1996;': [660, 682, 1015, 1044, 1699, 1727, 3505], '10:': [661, 683, 3506], '2527-2539Crossref': [662], '(607)': [665], '7Yost': [668], 'C.': [669, 3492], 'Torres': [670, 3493], 'Miller': [672, 3495], 'Huang': [674, 3497], 'E.': [675, 1457, 3498, 3797, 3855], 'Kimelman': [676, 3499], '1443-1454Crossref': [684, 3507], '(1018)': [687, 3510], 'may': [695, 1328, 3382, 3697, 3839], 'induce': [696], 'These': [701, 1294, 1597, 2443, 2516, 2668, 2781, 3167, 3459], 'actions': [702], 'consistent': [706, 2784, 3170], 'observation': [709], 'embryos,': [718], 'because': [719], 'accumulation': [721], 'induces': [724], '(8Funayama': [728], 'N.': [729, 3741, 3772], 'McCrea': [732], 'P.': [733, 781, 836, 870, 906, 955, 2046, 2182, 2216, 2410, 2427, 2479, 3025, 3255, 3272, 3311, 3336, 3635, 3791, 3799], 'Cell': [737], 'Biol.': [738, 872, 1209, 1697, 1725, 1755, 2218, 2828, 3027], '1995;': [739, 874, 963, 2054, 2220, 2435, 3029, 3280], '128:': [740], '959-968Crossref': [741], '(500)': [744], 'It': [747, 1224, 2379, 2574, 3243, 3513, 3707], 'shown': [750, 1227, 2160, 3246], 'besides': [752], 'requires': [761], 'tumor': [766], 'suppressor': [767], 'linked': [768], 'FAP': [770, 888, 3630], 'initiation': [774], 'sporadic': [776], 'human': [777, 3841], 'colorectal': [778, 890, 2582], 'cancer': [779, 3632, 3696, 3732], '(9Polakis': [780, 905, 2409, 3254, 3310, 3335, 3634], 'Biochim.': [782, 907, 2411, 3256, 3312, 3337, 3636], 'Biophys.': [783, 908, 2412, 3257, 3313, 3338, 3637], 'Acta.': [784, 909, 2413, 3258, 3314, 3339, 3638], '1332:': [786, 911, 2415, 3260, 3316, 3341, 3640], 'F127-F147PubMed': [787, 912, 2416, 3261, 3317, 3342, 3641], 'middle': [791], 'portion': [792], 'contains': [795, 2346, 2628, 2656, 2699, 2708, 2981, 3122, 3301], 'three': [796, 2657, 2711, 3237, 3304], 'successive': [797], '(aa)': [800], 'followed': [802], 'related': [805], 'distinct': [807, 2566, 3229], '20-aa': [808, 927, 1357, 2630, 2663, 2684, 2703, 2712, 2775, 3307, 3329, 3674], 'repeats.': [809, 933, 3675], 'Both': [810, 2716], 'types': [811], 'able': [815], 'independently': [818], '(10Rubinfeld': [821, 2167, 2464], 'B.': [822, 824, 849, 862, 864, 951, 953, 2042, 2044, 2168, 2170, 2195, 2208, 2210, 2423, 2425, 2465, 2467, 2492, 3017, 3019, 3268, 3270, 3753, 3776, 3789], 'Souza': [823, 863, 950, 2041, 2169, 2209, 2422, 2466, 3018, 3267], 'Albert': [825, 865, 948, 2039, 2171, 2211, 2420, 2468, 3020, 3265, 3794], 'I.': [826, 866, 949, 2040, 2172, 2212, 2421, 2469, 3021, 3266, 3795], 'Müller': [827, 2173, 2470], 'O.': [828, 1040, 1747, 2174, 2471], 'Chamberlain': [829, 2175, 2472], 'S.H.': [830, 2176, 2473], 'Masiarz': [831, 2177, 2474], 'F.R.': [832, 2178, 2475], 'Munemitsu': [833, 867, 2179, 2213, 2476, 3022], 'Polakis': [835, 869, 954, 2045, 2181, 2215, 2426, 2478, 3024, 3271, 3798], 'Science.': [837, 852, 2183, 2198, 2480, 2495, 3756, 3779, 3800], '1993;': [838, 853, 2184, 2199, 2481, 2496], '262:': [839, 854, 2185, 2200, 2482, 2497], '1731-1734Crossref': [840, 2186, 2483], '(1177)': [843, 2189, 2486], '11Su': [846, 2192, 2489], 'Vogelstein': [848, 2194, 2491, 3752, 3775], 'Kinzler': [850, 2196, 2493, 3750, 3777], 'K.W.': [851, 2197, 2494, 3751, 3778], '1734-1737Crossref': [855, 2201, 2498], '(1115)': [858, 2204, 2501], '12Rubinfeld': [861, 2207], 'Chem.': [873, 1210, 1698, 1726, 1756, 2219, 2829, 3028], '270:': [875, 2221, 3030], '5549-5555Abstract': [876, 2222, 3031], '(298)': [884, 2230, 3039], 'cancers,': [891], 'most': [892, 924, 3671], 'patients': [893, 3633], 'carry': [894], 'mutations': [896, 3484, 3648, 3692, 3714, 3823, 3830], 'result': [898, 3660], 'expression': [901], 'proteins': [904, 918, 1468, 1908, 1993, 2619, 2811, 2936, 3238], 'Almost': [915, 3644], 'all': [916, 3645], 'mutant': [917, 938, 1231], 'lack': [919], 'C-terminal': [921, 2530, 3668], 'half': [922, 2531, 3669], 'retain': [930, 1061], '15-aa': [932, 2658, 2767, 3324], 'Colorectal': [934], 'carcinoma': [935, 2583], 'contain': [940], 'large': [941], 'amounts': [942, 3405], 'monomeric': [944], '(13Munemitsu': [946, 2037], 'Rubinfeld': [952, 2043, 2424, 3269], 'Proc.': [956, 2047, 2428, 3273], 'Natl.': [957, 2048, 2429, 3274], 'Acad.': [958, 2049, 2430, 3275], 'Sci.': [959, 2050, 2431, 3276], 'U.': [960, 2051, 2432, 3277], '92:': [964, 2055, 2436, 3281], '3046-3050Crossref': [965, 2056, 2437, 3282], '(955)': [968, 2059, 2440, 3285], 'accumulated': [972], 'translocates': [974], 'nucleus,': [977], 'this': [979, 1115, 1645, 3349], 'translocation': [980], 'involves': [981], 'association': [983], 'transcription': [988], 'enhancers': [989], 'lymphocyte': [992], 'enhancer': [993], 'binding': [994, 1315, 2567, 2961, 3052, 3085, 3102, 3124, 3217, 3230, 3364, 3379], 'factor/T': [995], 'cell': [996, 2584, 3861], 'factor': [997], 'family': [998, 2808, 2958], '(14Behrens': [999], 'von': [1001], 'Kries': [1002], 'J.P.': [1003], 'Kühl': [1004], 'Bruhn': [1006], 'Wedlich': [1008], 'Grosschedl': [1010], 'R.': [1011, 3548, 3749], 'Birchmeier': [1012], 'Nature.': [1014], '382:': [1016], '638-642Crossref': [1017], '(2595)': [1020], '15Molenaar': [1023], 'van': [1025, 3744], 'de': [1026, 3747], 'Wetering': [1027], 'Oosterwegel': [1029], 'Peterson-Maduro': [1031], 'Godsave': [1033], 'Korinek': [1035, 3769], 'V.': [1036, 3739, 3770], 'Roose': [1037], 'Destrée': [1039], 'Clevers': [1041, 3754, 3773], '86:': [1045], '391-399Abstract': [1046], '(1618)': [1054], 'mutants': [1060, 1774, 1865, 2246, 2445, 2580, 2611, 2801, 3625, 3682], 'β-catenin-binding': [1063, 1103, 3197, 3835], 'activity,': [1064], 'interaction': [1066, 1809, 1929, 2691, 3132, 3159], 'sufficient': [1073, 3371], 'How': [1079], 'down-regulates': [1081, 3249], 'relationship': [1085], 'between': [1086], 'clear.': [1097], 'addition': [1099], 'GSK-3β-': [1101], 'sites,': [1104], 'homologous': [1111], 'called': [1118], '5Ikeda': [1157], 'originally': [1182], 'GTP-': [1191], 'GDP-bound': [1194], 'form': [1195, 2881], 'Gα': [1197, 1203], 'stimulates': [1199, 1364, 3612], 'GTP': [1200], 'hydrolysis': [1201], '(16Dohlman': [1204, 2823], 'H.G.': [1205, 2824], 'Thorner': [1206, 2825], '272:': [1212, 1758, 2831], '3871-3874Abstract': [1213, 2832], '(450)': [1221, 2840], 'ΔRGS,': [1229], 'deleted,': [1240], 'acts': [1241, 1299], 'potent': [1244], 'dorsalizer,': [1245], 'producing': [1246], 'secondary': [1248], 'axis-inducing': [1255], 'activity': [1256, 1309, 1331, 3290, 3466], 'ΔRGS': [1258, 1298], 'indicate': [1296, 1399, 3347, 3461, 3678], 'through': [1300, 2242], 'dominant-negative': [1302], 'inhibit': [1305], 'an': [1306, 1330, 2004, 3465], 'endogenous': [1307], 'competes': [1313], 'normally': [1322], 'interacts.': [1323], 'Therefore,': [1324, 2753, 2925, 3042, 3362, 3559, 3688, 3829], 'transmit': [1333], 'signal': [1335], 'interacting': [1337], 'other': [1339, 2937, 2963], 'protein(s).': [1340], 'Here': [1341], 'we': [1342, 2233, 2350, 3043, 3115], 'report': [1343], 'cDNA,': [1418], '293': [1419], 'cells,': [1420, 1422, 2396], 'were': [1428, 1469, 1485, 1502, 1514, 1530, 1593, 1688, 1775, 1790, 1799, 1849, 1857, 1875, 1909, 1916, 1975, 1994, 2017, 2065, 2082, 2100, 2109, 2253, 2451, 2509, 2614, 2714, 3070, 3408], 'kindly': [1429], 'supplied': [1430], 'from': [1431, 1471, 1487, 1504, 1515, 2819, 3414], 'Drs.': [1432, 3845], 'Akiyama': [1434], '(Osaka': [1435], 'University,': [1436, 1453, 1460], 'Suita,': [1437], 'Japan),': [1438, 1446, 1455, 1462], 'K.': [1439, 3848], 'Morishita': [1440], '(Daiichi': [1441], 'Pharmaceutical': [1442], 'Co.': [1443], 'Ltd.,': [1444], 'Tokyo,': [1445], 'Nagafuchi': [1448], 'Sh.': [1450, 3852], 'Tsukita': [1451], '(Kyoto': [1452], 'Kyoto,': [1454], 'Tahara': [1458, 3856], '(Hiroshima': [1459], 'Hiroshima,': [1461], 'respectively.': [1463, 1498], 'GST': [1464, 1989], 'MBP': [1466, 1906, 1991, 2617], 'fusion': [1467, 1907, 1992, 2618], 'purified': [1470, 2615], 'Escherichia': [1472], 'according': [1474], "manufacturer's": [1477], 'instructions.': [1478], 'anti-APC': [1480, 1803, 1861], '(Ab-1)': [1481], 'antibodies': [1484], 'purchased': [1486, 1503], 'Oncogene': [1488], 'Science': [1489], 'Inc.': [1490, 1506], '(Cambridge,': [1491], 'MA)': [1492], 'Transduction': [1494], 'Laboratories': [1495], '(Lexington,': [1496], 'KY),': [1497], '[35S]Methionine': [1499], '[35S]cysteine': [1501, 2070], 'Amersham': [1505], '(Buckinghamshire,': [1507], 'United': [1508], 'Kingdom).': [1509], 'Other': [1510], 'materials': [1511], 'chemicals': [1513], 'commercial': [1516], 'sources.': [1517], 'pEF-BOS-Myc/rAxin': [1518, 2026], '(full-length),': [1519, 1521, 1608, 2291], 'pBSKS/rAxin': [1520, 1609, 1637], 'pBJ-Myc/rAxin-(1–229),': [1522], 'pEF-BOS-Myc/rAxin-(1–713),': [1523], 'pBJ-Myc/rAxin-(298–713),': [1524], 'pEF-BOS/Myc-rAxin-(298–506),': [1525], 'pBJ-Myc/rAxin-(713–832),': [1526], 'pGEX-2T/β-catenin,': [1527], 'pMAL-c2/rAxin-(298–506)': [1529], 'constructed': [1531], 'described': [1533, 1601, 1691, 2036], 'To': [1556, 1575, 1605, 1634, 1653, 2597, 2688, 3385, 3473], 'construct': [1557, 1576, 1606, 1635, 1654], 'pGEX-2T/RGS,': [1558], 'cDNA': [1561, 1591, 1618, 1671], 'fragment': [1562, 1619, 1646, 1672, 3321], 'encoding': [1563], 'rAxin-(89–216)': [1564], 'was': [1565, 1582, 1610, 1620, 1625, 1638, 1647, 1657, 1673, 1818, 1825, 1934, 1938, 1967, 2033, 2287, 2302, 2329, 2340, 2372, 2642, 3107, 3291, 3401, 3450], 'synthesized': [1566], 'polymerase': [1568], 'chain': [1569], 'reaction': [1570, 1889, 1958], 'inserted': [1572, 1594, 1621, 1648, 1674], 'into': [1573, 1595, 1622, 1649, 1675], 'pGEX-2T.': [1574, 1652], 'pMAL-c2': [1577], 'mutants,': [1580], 'pMKITneo/APC': [1581], 'digested': [1583, 1611, 1626, 1639, 1658, 1666], 'various': [1585, 1878, 1947, 2609], 'restriction': [1586], 'enzymes,': [1587], 'fragments': [1592], 'pMAL-c2.': [1596], 'procedures': [1598], 'will': [1599], 'be': [1600, 2645, 3073, 3383, 3565, 3698], 'detail': [1603], 'elsewhere.': [1604], 'pMAL-c2/rAxin': [1607], 'SmaI': [1613, 1641, 1650], 'andEcoRV,': [1614], 'pMALc-2,': [1623], 'XbaI': [1628], 'blunted': [1630, 1661], 'Klenow': [1632, 1663], 'fragment.': [1633], 'pGEX-2T/rAxin-(1–529),': [1636], 'PvuII,': [1643], 'cut': [1651], 'pCGN/β-catenin,': [1655], 'pBSSK/β-catenin': [1656], 'XhoI,': [1660], 'fragment,': [1664], 'XbaI.': [1668], 'pCGN.': [1676], '(10-cm': [1679], 'diameter': [1680, 2015], 'dish)': [1681, 2016], 'transfected': [1682, 2018], 'pBJ-': [1684], 'pEF-BOS-derived': [1686], 'plasmids': [1687, 3859], 'lysed': [1689, 2083], '(17Kikuchi': [1692], 'Williams': [1694], 'L.T.': [1695], '271:': [1700, 1728], '588-594Abstract': [1701], '(63)': [1709], '18Hinoi': [1712], 'Ikeda': [1718, 1742], 'Matsuura': [1720, 1750], 'Y.': [1721, 1751], '19710-19716Abstract': [1729], '(36)': [1737], '19Murai': [1740], 'Ishida': [1746], 'Okazaki-Kishida': [1748], '10483-10490Abstract': [1759], '(56)': [1767], 'deletion': [1773, 1864, 2245, 2610], 'tagged': [1776], 'Myc': [1778], 'epitope': [1779], 'at': [1780, 1845, 1903, 1963, 2076, 2086, 2386, 3302, 3812], 'their': [1781, 3101, 3858, 3882], 'N': [1782], 'termini.': [1783], 'lysates': [1785, 1829, 2099, 3416], '(160–800': [1786], 'μg': [1787, 1831], 'protein)': [1789, 1833], 'immunoprecipitated': [1791, 2101, 2254, 3409], 'anti-Myc': [1794, 2257], 'antibody,': [1795, 2105], 'then': [1796], 'precipitates': [1798, 1856, 1915, 1974, 2108], 'probed': [1800, 1858, 1917, 1976, 2110], 'antibodies.': [1806], 'When': [1807, 1922, 3448], 'examined': [1819, 2234, 2351, 3045, 3116], 'vitro,': [1821], '1': [1822, 1897, 2297, 2322, 2377, 2457, 2514], 'μm': [1823], 'GST-RGS': [1824, 1848, 2375, 2455, 2623, 2649, 2717, 2742], 'incubated': [1826, 1876, 1939], '(200': [1830], 'L,': [1837], 'SW480,': [1838], '2': [1843, 1901, 1961, 2621, 2637, 2666, 2731, 2751], 'h': [1844, 1902, 1962, 3445], '4': [1846, 1904, 1964, 3444], '°C.': [1847, 1905, 1965, 2078], 'precipitated': [1850, 1910, 1968, 1988], 'glutathione-Sepharose': [1852, 1970], '4B,': [1853, 1971], 'antibody.': [1862, 1921, 1980, 2258], 'Various': [1863, 2244], 'MBP-APC': [1867], '(0.5–10': [1868], 'pmol)': [1869], 'immobilized': [1870], 'amylose': [1873], 'resin': [1874], 'concentrations': [1879, 1948], 'GST-RGS,': [1881], 'GST-rAxin-(1–529),': [1882], 'GST-β-catenin': [1884, 1966, 2512, 2719, 2734, 3056, 3089, 3161], '100': [1886, 1955], 'μl': [1887, 1956], 'mixture': [1890, 1959], '(20': [1891], 'mm': [1892, 1898], 'Tris/HCl': [1893], '(pH': [1894], '7.5)': [1895], 'dithiothreitol)': [1899], 'centrifugation,': [1912], 'anti-GST': [1920], 'effect': [1924, 3118], 'examined,': [1935], '50': [1936], 'nmGST-β-catenin': [1937], '250': [1941], 'nmMBP-APC-(959–1338)': [1942], 'presence': [1945], 'MBP-rAxin-(298–506)': [1950, 3059, 3082, 3110], 'MBP-rAxin': [1952, 3097], '(full-length)': [1953, 2307, 3098], 'anti-MBP': [1979], 'Where': [1981], 'specified,': [1982], 'relative': [1984], 'intensities': [1985], 'quantitated': [1995], 'densitometric': [1997], 'tracing': [1998], 'stained': [2001], 'sheets': [2002], 'using': [2003], 'NIH': [2005], 'image': [2006, 2122], 'program.': [2007], '(60–70%': [2010], 'confluent': [2011], '35-mm': [2014], 'pCGN/β-catenin': [2020, 2024], 'alone': [2021, 3422], '(full-length).': [2027], 'After': [2028], '60': [2029], 'h,': [2030], 'pulse-chase': [2031, 3394], 'analysis': [2032, 3395, 3432], 'performed': [2034], 'Briefly,': [2062], 'pulse-labeled': [2066], '[35S]methionine': [2068], '(50': [2071], 'μCi/ml)': [2072], '30': [2074], 'min': [2075], '37': [2077], 'Then': [2079], 'immediately': [2084], 'indicated': [2088], 'times': [2089], 'following': [2090], 'incubation': [2091], 'excess': [2093], 'unlabeled': [2094], 'methionine': [2095], 'cysteine.': [2097], 'anti-HA': [2104, 2113, 3412], 'antibody': [2114, 3413], 'analyzed': [2116], 'Fuji': [2119], 'BAS': [2120], '2000': [2121], 'analyzer.': [2123], 'found': [2127, 2973], 'whether': [2235, 2352, 2599, 3046, 3387], 'makes': [2237, 2360, 2525], 'Myc-rAxin': [2248, 2290, 2306, 3427, 3449], 'expressed': [2249], 'Consistent': [2259, 2459], 'coprecipitated': [2288, 2341, 2373, 2453, 2510], 'Myc-rAxin-(1–713),': [2292], 'Myc-rAxin-(298–713),': [2293], 'Myc-rAxin-(298–506)': [2295, 2318], '(Fig.': [2296, 2321, 2376, 2456, 2513, 2620, 2636, 2665, 2730, 2750, 3094, 3111, 3164, 3446, 3457], 'A).': [2298, 2323, 2622, 3096, 3113], 'Among': [2299], 'them,': [2300], 'detected': [2303, 2330], 'Myc-rAxin-(1–713)': [2309], 'immune': [2310, 2319, 2334], 'complexes,': [2311], 'Myc-rAxin-(298–713)': [2316], 'complexes': [2320], 'Unexpectedly,': [2324], 'Myc-rAxin-(1–229)': [2333], 'complex.': [2335, 3242], 'Neither': [2336], 'nor': [2338], 'Myc-rAxin-(713–832).': [2343], 'rAxin-(1–229)': [2345], 'domain,': [2349], 'itself': [2356], '(amino': [2357], 'acids': [2358, 2388], '89–216)': [2359], 'B).': [2378, 2458, 2515, 2638, 2667, 3166], '1337': [2389], '1427': [2391], 'respectively,': [2397], 'forms': [2402], 'fail': [2405], 'down-regulate': [2407, 3333, 3474], 'Scholar,13Munemitsu': [2418, 3263], 'previous': [2462], 'intact': [2535], 'sites': [2568, 3125, 3198, 3231, 3836], 'GSK-3β.': [2573], 'notable': [2576], 'lines': [2585], 'such': [2586], 'do': [2592, 3203, 3683], 'associate': [2594], 'rAxin.': [2596, 2899, 3143, 3361, 3687], 'examine': [2598], 'MBP-APC-(1211–2075),': [2626], 'dose-dependent': [2634, 3064, 3092, 3151], 'manner': [2635, 3093], 'TheK': [2639], 'd': [2640, 3068], 'value': [2641], 'calculated': [2643, 3071], '115': [2646], 'nm.': [2647], 'did': [2650, 3154], 'MBP-APC-(959–1338)': [2654, 3061, 3087], 'first': [2662, 2771, 2949, 3328], 'repeat': [2664, 3308, 3330], 'show': [2670], 'characterize': [2689], 'further,': [2696], 'MBP-APC-(1211–1787),': [2697, 2722, 3136], 'former': [2701], 'four': [2702], 'MBP-APC-(1788–2075),': [2706], 'purified.': [2715], 'they': [2724, 3221], 'MBP-APC-(1788–2075)': [2727], 'less': [2728, 3108], 'efficiently': [2729], 'C).': [2732, 2752], 'MBP-APC-(1211–1495)': [2738, 2749], 'MBP-APC-(1475–1787),': [2740], 'whereas': [2741], 'MBP-APC-(1475–1787)': [2745], 'does': [2757, 3210, 3331], 'interact': [2759, 3685], 'second': [2774], 'associated': [2797], 'A': [2807], 'eukaryotic': [2816], 'species': [2817], 'ranging': [2818], 'yeast': [2820], 'mammals': [2822], 'three-dimensional': [2844], 'structure': [2845], 'stable': [2848], 'RGS4': [2851, 2890, 2904], 'Gαi1': [2853, 2910], 'determined': [2856], '(20Tesmer': [2857], 'J.J.G.': [2858], 'Berman': [2859], 'D.M.': [2860], 'Gilman': [2861], 'A.G.': [2862], 'Sprang': [2863], 'S.R.': [2864], '89:': [2867], '251-261Abstract': [2868], '(687)': [2876], 'Residues': [2879], 'hydrophobic': [2883], 'core': [2884], 'box': [2888], 'well': [2892], 'conserved': [2893, 2913], '11': [2901], 'residues': [2902], 'direct': [2907], 'contact': [2908], 'except': [2920], 'one': [2922], 'acid.': [2924], 'conceivable': [2928], 'than': [2938, 2964, 3109], 'α': [2940, 2966], 'subunit': [2941, 2967], 'proteins.': [2944, 2970, 3224], 'Our': [2945, 3345, 3676], 'demonstration': [2950], 'member': [2953], 'partner': [2962], 'rAxin-(298–506)': [2975], 'β-catenin-(175–423),': [2979], 'armadillo': [2982, 3011], '2–7': [2984], '2–10': [3013], '(12Rubinfeld': [3016], 'next': [3044], 'share': [3050], 'site': [3053, 3488, 3534, 3723], 'manner,': [3065, 3152], 'theirK': [3067], 'values': [3069], '227': [3074], 'nmand': [3075], '273': [3076], 'nm,': [3077], 'respectively': [3078], '(data': [3079, 3433], 'shown).': [3081], 'inhibited': [3083, 3100], '3': [3095, 3112, 3165], 'inhibitory': [3105], 'efficiency': [3106], 'rAxin-(1–529),': [3120], 'Although': [3144, 3403], 'GST-rAxin-(1–529)': [3145], 'MBP-APC-(1211–1787)': [3148, 3163], 'affect': [3156], 'significantly': [3157], 'APC-(1211–1787)': [3176], 'prefers': [3178], 'APC-(1211–1495)': [3179], 'APC-(1475–1787);': [3181], 'inversely': [3182], 'APC-(1475–1787)': [3188], 'APC-(1211–1495).': [3192], 'together,': [3194], 'compete': [3212], 'when': [3220, 3530], 'since': [3226], 'level': [3251], 'This': [3288], 'localized': [3292], 'central': [3295], 'least': [3303, 3813], 'sequence': [3309, 3658, 3719], 'decreasing': [3373], 'level,': [3376], 'necessary.': [3384], 'investigate': [3386], 'expressing': [3399, 3420], 'HA-β-catenin': [3400, 3407, 3421, 3425, 3437, 3452], 'performed.': [3402], 'equivalent': [3404], 'coexpressing': [3424], 'assessed': [3429], 'immunoblot': [3431], 'shown),': [3435], 'pulse-labeled.': [3436], 'gradually': [3438], 'decreased': [3439], 'half-life': [3442, 3456], '4).': [3447, 3458], 'cotransfected,': [3451], 'exhibited': [3453], 'shorter': [3455], 'stimulate': [3468], 'required,': [3481], 'stabilize': [3489], '(7Yost': [3491], 'reported': [3516, 3628, 3710], 'ubiquitinated': [3521], 'ubiquitination': [3525], 'abolished': [3529], 'mutated': [3538], '(21Aberle': [3539], 'Bauer': [3541], 'Stappert': [3543], 'Kispert': [3545], 'Kemler': [3547], '16:': [3552], '3797-3804Crossref': [3553], '(2160)': [3556], 'regulated': [3566], 'ubiquitination-proteasome': [3569], 'present': [3606], 'strongly': [3608], 'cooperation': [3618], 'Literally': [3621], 'hundreds': [3622], 'confined': [3650], '5′-half': [3653], 'coding': [3657], 'truncation': [3662], 'lacks': [3666], 'reason': [3690], 'why': [3691], 'cause': [3695, 3840], 'due': [3699, 3821], 'inability': [3702], 'there': [3712, 3810], 'serine': [3716], 'consensus': [3718], 'melanoma': [3729], 'colon': [3731], 'normal': [3735], '(22Korinek': [3738], 'Barker': [3740, 3771], 'Morin': [3742], 'P.J.': [3743, 3766], 'Wichen': [3745], 'Weger': [3748], '275:': [3758, 3781, 3802], '1784-1787Crossref': [3759], '(2935)': [3762], '23Morin': [3765], 'Sparks': [3767], 'A.B.': [3768], '1787-1790Crossref': [3782], '(3504)': [3785], '24Rubinfeld': [3788], 'Robbins': [3790], 'El-Gamil': [3792], 'Porfiri': [3796], '1790-1792Crossref': [3803], '(1135)': [3806], 'Thus,': [3809], 'two': [3814], 'ways': [3815], 'increase': [3817], 'levels': [3818], 'itself.': [3828], 'APC-,': [3832], 'GSK-3β-,': [3833], 'cancer.': [3842], 'thank': [3844, 3866], 'Akiyama,': [3847], 'Morishita,': [3849], 'Nagafuchi,': [3851], 'Tsukita,': [3853], 'lines.': [3862], 'wish': [3864], 'Research': [3868], 'Center': [3869], 'Molecular': [3871], 'Medicine,': [3872, 3877], 'Hiroshima': [3873], 'University': [3874], 'School': [3875], 'use': [3880], 'facilities.': [3883]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2051032088', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 21}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 15}], 'updated_date': '2025-01-12T20:37:50.642572', 'created_date': '2016-06-24'}