Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2050722710', 'doi': 'https://doi.org/10.1128/jb.182.17.4696-4703.2000', 'title': 'Microarray-Based Identification of a Novel <i>Streptococcus pneumoniae</i> Regulon Controlled by an Autoinduced Peptide', 'display_name': 'Microarray-Based Identification of a Novel <i>Streptococcus pneumoniae</i> Regulon Controlled by an Autoinduced Peptide', 'publication_year': 2000, 'publication_date': '2000-09-01', 'ids': {'openalex': 'https://openalex.org/W2050722710', 'doi': 'https://doi.org/10.1128/jb.182.17.4696-4703.2000', 'mag': '2050722710', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10940007', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/111343'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jb.182.17.4696-4703.2000', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S133274750', 'display_name': 'Journal of Bacteriology', 'issn_l': '0021-9193', 'issn': ['0021-9193', '1067-8832', '1098-5530'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1128/jb.182.17.4696-4703.2000', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5011471587', 'display_name': 'Antoine de Saizieu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Antoine de Saizieu', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035950712', 'display_name': 'Christophe Gardès', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Christophe Gardès', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011212433', 'display_name': 'Nicholas Flint', 'orcid': 'https://orcid.org/0000-0003-1118-4223'}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Nicholas Flint', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062042335', 'display_name': 'Christian Wagner', 'orcid': 'https://orcid.org/0000-0001-7788-4594'}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Christian Wagner', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077297795', 'display_name': 'Markus Kamber', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Markus Kamber', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057937276', 'display_name': 'Timothy J. Mitchell', 'orcid': 'https://orcid.org/0000-0002-8309-5556'}, 'institutions': [{'id': 'https://openalex.org/I7882870', 'display_name': 'University of Glasgow', 'ror': 'https://ror.org/00vtgdb53', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I7882870']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Timothy J. Mitchell', 'raw_affiliation_strings': ['Infection and Immunity, University of Glasgow, Glasgow G12 8QQ, Scotland2'], 'affiliations': [{'raw_affiliation_string': 'Infection and Immunity, University of Glasgow, Glasgow G12 8QQ, Scotland2', 'institution_ids': ['https://openalex.org/I7882870']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087707404', 'display_name': 'Wolfgang Keck', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Wolfgang Keck', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000775853', 'display_name': 'Kurt E. Amrein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Kurt E. Amrein', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103812103', 'display_name': 'Roland Lange', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I118019719', 'display_name': 'Roche (Switzerland)', 'ror': 'https://ror.org/00by1q217', 'country_code': 'CH', 'type': 'company', 'lineage': ['https://openalex.org/I118019719']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Roland Lange', 'raw_affiliation_strings': ['Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and'], 'affiliations': [{'raw_affiliation_string': 'Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland,1 and', 'institution_ids': ['https://openalex.org/I118019719']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 17.449, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 236, 'citation_normalized_percentile': {'value': 0.999928, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '182', 'issue': '17', 'first_page': '4696', 'last_page': '4703'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10654', 'display_name': 'Management and Epidemiology of Pneumonia', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10654', 'display_name': 'Management and Epidemiology of Pneumonia', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Physiology and Genetics', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'Ribosome Structure and Translation Mechanisms', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/regulon', 'display_name': 'Regulon', 'score': 0.8649815}, {'id': 'https://openalex.org/keywords/response-regulator', 'display_name': 'Response regulator', 'score': 0.47761342}, {'id': 'https://openalex.org/keywords/rna-regulation', 'display_name': 'RNA Regulation', 'score': 0.470928}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8710966}, {'id': 'https://openalex.org/C62361671', 'wikidata': 'https://www.wikidata.org/wiki/Q1754612', 'display_name': 'Regulon', 'level': 4, 'score': 0.8649815}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.641907}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.5749845}, {'id': 'https://openalex.org/C2781196521', 'wikidata': 'https://www.wikidata.org/wiki/Q24965710', 'display_name': 'Response regulator', 'level': 4, 'score': 0.47761342}, {'id': 'https://openalex.org/C47289529', 'wikidata': 'https://www.wikidata.org/wiki/Q908550', 'display_name': 'Open reading frame', 'level': 4, 'score': 0.43394798}, {'id': 'https://openalex.org/C167625842', 'wikidata': 'https://www.wikidata.org/wiki/Q899763', 'display_name': 'Peptide sequence', 'level': 3, 'score': 0.43327203}, {'id': 'https://openalex.org/C165864922', 'wikidata': 'https://www.wikidata.org/wiki/Q411391', 'display_name': 'Regulation of gene expression', 'level': 3, 'score': 0.31800222}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005798', 'descriptor_name': 'Genes, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D018085', 'descriptor_name': 'Regulon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013296', 'descriptor_name': 'Streptococcus pneumoniae', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000483', 'descriptor_name': 'Alleles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001430', 'descriptor_name': 'Bacteriocins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001430', 'descriptor_name': 'Bacteriocins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004269', 'descriptor_name': 'DNA, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015964', 'descriptor_name': 'Gene Expression Regulation, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014644', 'descriptor_name': 'Genetic Variation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016680', 'descriptor_name': 'Genome, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071677', 'descriptor_name': 'Histidine Kinase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005810', 'descriptor_name': 'Multigene Family', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011494', 'descriptor_name': 'Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013296', 'descriptor_name': 'Streptococcus pneumoniae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013296', 'descriptor_name': 'Streptococcus pneumoniae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015533', 'descriptor_name': 'Transcriptional Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jb.182.17.4696-4703.2000', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S133274750', 'display_name': 'Journal of Bacteriology', 'issn_l': '0021-9193', 'issn': ['0021-9193', '1067-8832', '1098-5530'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111343', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10940007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jb.182.17.4696-4703.2000', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S133274750', 'display_name': 'Journal of Bacteriology', 'issn_l': '0021-9193', 'issn': ['0021-9193', '1067-8832', '1098-5530'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1566935054', 'https://openalex.org/W1574722357', 'https://openalex.org/W1590971388', 'https://openalex.org/W1763808251', 'https://openalex.org/W1943112463', 'https://openalex.org/W1971649516', 'https://openalex.org/W2002398424', 'https://openalex.org/W2013437656', 'https://openalex.org/W2042050496', 'https://openalex.org/W2044940816', 'https://openalex.org/W2047929024', 'https://openalex.org/W2061181988', 'https://openalex.org/W2063195137', 'https://openalex.org/W2069271664', 'https://openalex.org/W2071123327', 'https://openalex.org/W2071578025', 'https://openalex.org/W2074726414', 'https://openalex.org/W2075798531', 'https://openalex.org/W2080357982', 'https://openalex.org/W2088970163', 'https://openalex.org/W2093257123', 'https://openalex.org/W2094176470', 'https://openalex.org/W2114243074', 'https://openalex.org/W2130494035', 'https://openalex.org/W2134555745', 'https://openalex.org/W2146122066', 'https://openalex.org/W2149332722', 'https://openalex.org/W2152882631', 'https://openalex.org/W2159638147', 'https://openalex.org/W2160102371', 'https://openalex.org/W2164101095', 'https://openalex.org/W2167435540', 'https://openalex.org/W2169029990', 'https://openalex.org/W2170704198', 'https://openalex.org/W2403115227', 'https://openalex.org/W2764167475', 'https://openalex.org/W4247420482', 'https://openalex.org/W578366578', 'https://openalex.org/W644043563'], 'related_works': ['https://openalex.org/W307040268', 'https://openalex.org/W2894524071', 'https://openalex.org/W2218874127', 'https://openalex.org/W2116356176', 'https://openalex.org/W2103386164', 'https://openalex.org/W2073126679', 'https://openalex.org/W2058874218', 'https://openalex.org/W2030078651', 'https://openalex.org/W1976388816', 'https://openalex.org/W1786268878'], 'abstract_inverted_index': {'We': [0, 206], 'have': [1, 78], 'identified': [2, 72], 'in': [3, 40, 158], 'the': [4, 29, 35, 66, 79, 90, 95, 143, 159, 182, 186, 211, 216, 225], 'Streptococcus': [5], 'pneumoniae': [6], 'genome': [7], 'sequence': [8, 192, 218, 223], 'a': [9, 53, 58, 105, 113, 117, 138, 150, 190, 221], 'two-component': [10], 'system': [11, 55, 93], '(TCS13,': [12], 'Blp': [13, 67], '[bacteriocin-like': [14], 'peptide])': [15], 'which': [16], 'is': [17, 52, 87, 123, 210, 220], 'closely': [18], 'related': [19], 'to': [20, 81, 89, 142], 'quorum-sensing': [21], 'systems': [22], 'regulating': [23], 'cell': [24], 'density-dependent': [25], 'phenotypes': [26], 'such': [27], 'as': [28], 'development': [30], 'of': [31, 37, 65, 103, 110, 125, 131, 146, 153, 172, 181, 185, 201], 'genetic': [32], 'competence': [33], 'or': [34], 'production': [36], 'antimicrobial': [38], 'peptides': [39], 'lactic': [41], 'acid': [42], 'bacteria.': [43], 'In': [44], 'this': [45, 129], 'study': [46], 'we': [47, 71], 'present': [48], 'evidence': [49], 'that': [50, 56, 77, 86, 137, 208], 'TCS13': [51], 'peptide-sensing': [54], 'controls': [57], 'regulon': [59], 'including': [60], 'genes': [61, 188], 'encoding': [62], 'Blps.': [63], 'Downstream': [64], 'TCS': [68], '(BlpH': [69], 'R)': [70], 'open': [73], 'reading': [74], 'frames': [75], '(blpAB)': [76], 'potential': [80], 'encode': [82], 'an': [83], 'ABC': [84], 'transporter': [85], 'homologous': [88], 'ComA/B': [91], 'export': [92], 'for': [94, 213, 224], 'competence-stimulating': [96], 'peptide': [97, 115, 122], 'ComC.': [98], 'The': [99, 156], 'putative': [100], 'translation': [101], 'product': [102], 'blpC,': [104], 'small': [106], 'gene': [107, 175, 178], 'located': [108], 'downstream': [109], 'blpAB,': [111], 'has': [112], 'leader': [114, 121], 'with': [116], 'Gly-Gly': [118], 'motif.': [119], 'This': [120], 'typical': [124], 'precursors': [126], 'processed': [127, 144], 'by': [128, 163, 195], 'family': [130], 'transporters.': [132], 'Microarray-based': [133], 'expression': [134, 160], 'profiling': [135], 'showed': [136], 'synthetic': [139, 164], 'oligopeptide': [140], 'corresponding': [141, 174], 'form': [145], 'BlpC': [147], '(BlpC*)': [148], 'induces': [149], 'distinct': [151], 'set': [152], '16': [154], 'genes.': [155], 'changes': [157], 'profile': [161], 'elicited': [162], 'BlpC*': [165, 214], 'depend': [166], 'on': [167], 'BlpH': [168, 209], 'since': [169], 'insertional': [170], 'inactivation': [171], 'its': [173], 'abolishes': [176], 'differential': [177], 'induction.': [179], 'Comparison': [180], 'promoter': [183, 204], 'regions': [184], 'blp': [187], 'disclosed': [189], 'conserved': [191, 217], 'element': [193, 219], 'formed': [194], 'two': [196], 'imperfect': [197], 'direct': [198], 'repeats': [199], 'upstream': [200], 'extended': [202], '-10': [203], 'elements.': [205], 'propose': [207], 'sensor': [212], 'and': [215], 'recognition': [222], 'BlpR': [226], 'response': [227], 'regulator.': [228]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2050722710', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 11}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-09-09T13:19:22.885491', 'created_date': '2016-06-24'}