Publication Information

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'https://openalex.org/W731244'], 'related_works': ['https://openalex.org/W4206543625', 'https://openalex.org/W3160935903', 'https://openalex.org/W3141381135', 'https://openalex.org/W2890216096', 'https://openalex.org/W2671342613', 'https://openalex.org/W2108613687', 'https://openalex.org/W2034598207', 'https://openalex.org/W1992892304', 'https://openalex.org/W1981766448', 'https://openalex.org/W1829401748'], 'abstract_inverted_index': {'IL-33/IL-1F11': [0, 212], 'is': [1, 17, 213, 229, 425, 482, 1273, 1436, 1577, 1607, 2139, 2153, 2173, 2275, 2394, 2401, 2534, 2567, 3173, 3268, 3297, 3711, 3963, 3976, 3989, 4008, 4014, 4110, 4146, 4262, 4287, 4293, 4301], 'a': [2, 45, 63, 139, 160, 167, 214, 257, 275, 351, 372, 379, 426, 932, 1578, 1726, 1931, 2166, 2177, 2392, 2395, 2413, 2611, 2684, 2715, 2730, 2846, 3900, 3906, 3918, 3992, 4134, 4242, 4288, 4508], 'new': [3, 57, 161, 215, 269, 373, 427], 'member': [4, 216, 428], 'of': [5, 20, 35, 50, 126, 174, 183, 196, 207, 217, 232, 247, 262, 338, 386, 395, 408, 419, 429, 505, 1438, 1507, 1581, 1745, 1859, 1906, 1933, 1956, 2134, 2145, 2234, 2322, 2461, 2470, 2511, 2592, 2600, 2633, 2683, 2705, 2718, 2737, 2748, 2765, 2826, 2834, 2898, 2917, 2948, 2953, 2964, 2984, 3093, 3260, 3277, 3301, 3386, 3390, 3405, 3478, 3507, 3607, 3641, 3653, 3706, 3899, 3971, 3987, 4037, 4107, 4194, 4218, 4271, 4303, 4502, 4519], 'the': [6, 18, 73, 81, 124, 149, 180, 197, 205, 218, 230, 285, 293, 336, 361, 392, 409, 417, 430, 1274, 1430, 2030, 2132, 2142, 2232, 2319, 2450, 2462, 2509, 2589, 2598, 2620, 2628, 2636, 2702, 2763, 2769, 2823, 2893, 2899, 2908, 2915, 2951, 2970, 2982, 3074, 3123, 3176, 3274, 3283, 3291, 3298, 3383, 3402, 3406, 3508, 3604, 3648, 3651, 3665, 3703, 3726, 3914, 3968, 3984, 3996, 4035, 4104, 4124, 4184, 4192, 4216, 4250, 4256, 4266, 4499, 4517], 'IL-1': [7, 23, 127, 219, 235, 339, 431, 1441, 1518, 4520], 'family': [8, 220, 432, 1928, 4521], 'ligand': [9, 19, 221, 231, 433, 1275], 'and': [10, 22, 40, 79, 91, 107, 116, 136, 141, 158, 222, 234, 252, 291, 303, 319, 328, 348, 353, 370, 525, 739, 934, 940, 1440, 1512, 1586, 1606, 1690, 1734, 1741, 1851, 1912, 1925, 1938, 2027, 2033, 2151, 2236, 2453, 2687, 2724, 2761, 2776, 2822, 2830, 2836, 2926, 2930, 3044, 3061, 3071, 3077, 3082, 3086, 3108, 3120, 3175, 3380, 3500, 3573, 3582, 3590, 3717, 3748, 3913, 4011, 4023, 4043, 4057, 4068, 4083, 4127, 4137, 4225, 4236, 4254, 4269, 4276, 4297, 4299, 4470, 4497, 4526], 'provokes': [11, 223], 'T': [12, 224, 489, 497], 'helper-type': [13, 225], 'immune': [14, 192, 226, 404, 519, 1910, 2708], 'responses.': [15, 193, 227, 405], 'IL-33': [16, 51, 162, 170, 184, 208, 228, 263, 374, 382, 396, 420, 481, 819, 928, 1431, 1746, 1854, 1907, 1913, 2325, 2614, 2720, 2733, 2749, 2842, 2954, 2965, 2988, 3079, 3182, 3204, 3463, 3496, 3510, 3578, 3586, 3655, 3972, 4045, 4056, 4059, 4070, 4108, 4227, 4238], 'ST2': [21, 233, 1277, 1439, 1576, 1850, 4240], 'receptor': [24, 236, 1293, 1432, 1442, 1494, 4252], 'accessory': [25, 237, 1443], 'protein': [26, 84, 238, 296, 944, 1444, 1514, 2036, 2179, 2993, 3055], '(IL-1RAcP)': [27, 239, 1445], 'that': [28, 52, 179, 240, 264, 391, 434, 927, 1575, 1844, 2226, 2273, 2833, 2967, 3041, 3170, 3249, 3273, 3571, 3650, 4028, 4103, 4182, 4233, 4247, 4292], 'triggers': [29, 241], 'nuclear': [30, 242, 439, 500, 935, 1502], 'factor-κ': [31, 243, 501, 1503], 'light': [32, 244, 502, 1504], 'chain': [33, 245, 503, 1505], 'enhancer': [34, 246, 504, 1506], 'activated': [36, 248, 506, 1508], 'B': [37, 249, 507, 1509], 'cells': [38, 250, 535, 673, 1510, 1583, 1611, 1730, 2760, 2936, 3085, 3256, 3502, 4087], '(NF-κB)': [39, 251, 1511], 'MAPK': [41, 253], 'signaling.': [42, 254], 'We': [43, 68, 255, 280, 2755], 'discovered': [44, 256, 437, 1289, 2613], 'novel': [46, 258, 2685, 2716], 'short': [47, 259, 3919, 4185], 'splice': [48, 163, 260, 375, 2593, 2615, 2721, 3737], 'variant': [49, 261, 2616, 2722], 'was': [53, 104, 112, 166, 265, 316, 324, 378, 435, 1287, 2739, 2843, 2955, 2979, 3056, 3101, 3109, 3408, 3483, 3587, 3593, 3657, 3700, 4076], 'termed': [54, 266], 'spIL-33.': [55, 267, 3097], 'The': [56, 88, 101, 120, 172, 268, 300, 313, 332, 384, 2681, 2735, 2839, 2961, 3098, 3639, 4066, 4140, 4210], 'spIL-33': [58, 70, 83, 90, 103, 122, 177, 198, 270, 282, 295, 302, 315, 334, 389, 410, 2634, 2686, 2693, 2706, 2725, 2738, 2757, 2827, 2891, 3045, 3076, 3988, 4007, 4067, 4195, 4204, 4224, 4235, 4248, 4272], 'lacks': [59, 271, 2619, 2892], 'exon': [60, 272, 2621, 2630, 2766, 3931], '3': [61, 273, 2037, 2622, 2631, 2767, 4280], 'containing': [62, 274, 3995], 'proposed': [64, 276, 2637, 3286, 3997], 'caspase-1': [65, 277, 2278, 2638, 2771, 2949, 2968, 3060, 3094, 3105, 3179, 3278, 3998, 4018], 'cleavage': [66, 278, 2181, 2233, 2639, 2772, 3095, 3275, 3302, 3389, 3999, 4019, 4036], 'site.': [67, 279], 'isolated': [69, 281], 'cDNA': [71, 283, 2747], 'from': [72, 284, 441, 2391, 2412, 2750, 3265, 3580, 3603, 3978, 4050, 4061], 'Huh7': [74, 286, 2759], 'human': [75, 287, 510, 1587, 2605, 2719, 2752, 2922, 2976, 3498, 3661, 3716, 4081, 4274], 'hepatocarcinoma': [76, 288], 'cell': [77, 289, 2753, 3267, 3662], 'line': [78, 290], 'expressed': [80, 292, 1608, 1849], 'recombinant': [82, 89, 102, 121, 294, 301, 314, 333, 2991, 3042, 3053, 3075, 3099, 3462, 4038, 4054, 4223], 'in': [85, 114, 138, 209, 297, 326, 350, 421, 487, 1584, 1908, 1936, 1961, 2029, 2324, 2398, 2604, 2623, 2694, 2707, 2758, 2914, 2924, 2932, 2950, 2957, 2985, 3037, 3113, 3181, 3254, 3258, 3400, 3497, 3733, 3740, 3930, 3991, 4004, 4079, 4150, 4199, 4273, 4295], 'Escherichia': [86, 298], 'coli.': [87, 299], 'pro-IL-33': [92, 304, 2274, 2835, 2901, 2992, 3043, 3100, 3172, 3253, 3263, 3387, 3407, 3479, 4040, 4075], 'were': [93, 305, 2828, 3047, 3091, 3458, 4030, 4060, 4071], 'not': [94, 306, 2164, 3048, 3102, 3111, 3280, 4015, 4031, 4048, 4077], 'cleaved': [95, 307, 3049, 3103], 'by': [96, 188, 308, 400, 533, 1855, 2277, 2445, 2537, 2981, 3050, 3059, 3104, 3178, 3206, 3303, 3388, 3410, 3485, 3595, 3647, 3668, 4112, 4222], 'caspase-1,': [97, 309, 3051], 'unlike': [98, 310], 'IL-18': [99, 311, 2237, 3067, 4439, 4527], '(IL-1F4).': [100, 312], 'constitutively': [105, 168, 175, 317, 380, 387, 2691, 2731, 4009], 'active,': [106, 318, 3174, 4073], 'spIL-33-induced': [108, 150, 320, 362], 'inflammatory': [109, 210, 321, 422, 823, 1732, 1921, 1939, 2146, 2227, 2848, 2910, 2918, 3088, 3115, 4206, 4219], 'cytokine': [110, 151, 322, 363, 933, 2849, 3734], 'production': [111, 323, 4217], 'caspase-1-independent': [113, 325], 'HMC-1': [115, 327, 3081, 4082], 'Raw': [117, 329, 2934, 3083, 4085], '264.7': [118, 330, 2935, 3084, 4086], 'cells.': [119, 331, 3584], 'induced': [123, 335, 3087, 4221], 'phosphorylation': [125, 337], 'receptor-associated': [128, 340, 1519, 1522], 'kinase': [129, 341], '(IRAK1),': [130, 342], 'NF-κB,': [131, 343, 499], 'p38': [132, 344], 'MAPK,': [133, 135, 345, 347], 'p44/42': [134, 346], 'JNK': [137, 349], 'time-': [140, 352], 'dose-dependent': [142, 354], 'manner.': [143, 355], 'Anti-ST2': [144, 356], 'monoclonal': [145, 357, 4212], 'antibody': [146, 358, 4213], 'specifically': [147, 359, 3057], 'blocked': [148, 360], 'production.': [152, 364], 'In': [153, 365], 'this': [154, 366, 2607, 2710, 3454, 3537], 'study,': [155, 367, 2608, 2711, 3455], 'we': [156, 368, 2609, 2712, 2743, 4029, 4188, 4245], 'identified': [157, 369], 'characterized': [159, 371, 2610, 2728, 3902], 'variant,': [164, 376], 'which': [165, 377, 1286, 2386, 2465, 2618, 2978, 3090, 3296, 3482, 3493, 3962], 'active': [169, 176, 381, 388, 2692, 2732, 3064, 3112, 4010, 4078], 'isoform.': [171, 383, 2734], 'existence': [173, 385, 2682], 'suggests': [178, 390], 'biological': [181, 393, 2590, 2824, 3384, 3403, 3505, 4121, 4128, 4258, 4306, 4500], 'activity': [182, 394, 2825, 3385, 3404, 3506, 4013, 4193, 4501], 'could': [185, 397, 4506], 'be': [186, 398, 485, 1916, 2156, 2170, 3645, 4507], 'triggered': [187, 399], 'diverse': [189, 401], 'stimulations': [190, 402], 'during': [191, 403], 'Further': [194, 406, 3201], 'investigation': [195, 407, 4261], 'expression': [199, 411, 4138, 4267], 'pattern': [200, 412, 4268], 'may': [201, 413, 929, 3644], 'contribute': [202, 414], 'to': [203, 415, 484, 1853, 1915, 1919, 2149, 2155, 2169, 2408, 2467, 2508, 2570, 2745, 2906, 3122, 3536, 3926, 3965, 4033, 4190, 4201, 4264], 'understanding': [204, 416, 2599], 'involvement': [206, 418], 'disorders.': [211, 423], 'IntroductionIL-33': [424], 'originally': [436, 1288], 'as': [438, 826, 931, 1280, 1290, 1501, 2159, 2176, 2449, 2729, 2845, 2921, 3744, 4241, 4284, 4331, 4524], 'factor': [440, 937, 1523], 'high': [442, 941, 1857], 'endothelial': [443, 513, 3501], 'venules': [444], '(1Baekkevold': [445], 'E.S.': [446], 'Roussigné': [447], 'M.': [448, 460, 594, 647, 683, 788, 792, 808, 956, 1058, 1110, 1131, 1221, 1223, 1241, 1309, 1343, 1543, 1659, 1663, 1679, 1694, 1696, 1714, 1812, 1873, 1971, 1973, 2011, 2043, 2045, 2197, 2294, 2480, 2546, 2656, 2793, 2865, 3009, 3141, 3361, 3512, 3843, 4309, 4334, 4336, 4340, 4419, 4475], 'Yamanaka': [449], 'T.': [450, 588, 598, 614, 677, 687, 742, 950, 960, 976, 1050, 1087, 1089, 1093, 1169, 1206, 1394, 1409, 1413, 1415, 1417, 1748, 1820, 3543, 3612, 3673, 3755, 3777, 3878, 4445, 4447, 4477], 'Johansen': [451], 'F.E.': [452], 'Jahnsen': [453], 'F.L.': [454], 'Amalric': [455], 'F.': [456, 838, 2063, 3779], 'Brandtzaeg': [457], 'P.': [458, 906, 1114, 1341, 1977, 1995, 2059, 2366, 2482, 3229, 3341, 3434, 3775], 'Erard': [459], 'Haraldsen': [461], 'G.': [462, 561, 645, 709, 840, 1031, 1116, 1202, 1307, 1335, 1469, 1541, 1619, 1773, 1883, 1979, 2076, 2195, 2241, 2292, 2360, 2575, 2654, 2791, 2863, 3007, 3139, 3223, 3335, 3428, 3936, 4155], 'Girard': [463, 1032, 1154, 2332, 3186, 3307], 'J.P.': [464, 1033, 1155, 2333, 3187, 3308], 'Am.': [465], 'J.': [466, 543, 548, 563, 600, 633, 649, 689, 710, 763, 770, 962, 1069, 1098, 1140, 1178, 1210, 1242, 1262, 1295, 1311, 1345, 1453, 1458, 1529, 1545, 1620, 1634, 1641, 1715, 1774, 1787, 1794, 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'PubMed': [476, 553, 580, 608, 627, 667, 697, 715, 734, 755, 782, 814, 847, 869, 917, 970, 989, 1013, 1042, 1075, 1104, 1145, 1161, 1190, 1215, 1247, 1268, 1329, 1349, 1368, 1380, 1401, 1424, 1463, 1488, 1563, 1601, 1625, 1653, 1685, 1720, 1761, 1779, 1806, 1834, 1896, 1949, 2001, 2022, 2108, 2126, 2217, 2249, 2263, 2314, 2342, 2380, 2436, 2497, 2527, 2554, 2582, 2676, 2813, 2885, 3029, 3161, 3196, 3243, 3317, 3355, 3373, 3448, 3530, 3565, 3634, 3695, 3769, 3796, 3831, 3890, 3957, 4176, 4321, 4346, 4370, 4404, 4434, 4465, 4492], 'Scopus': [477, 554, 581, 609, 628, 668, 698, 716, 735, 756, 783, 815, 848, 870, 918, 971, 990, 1014, 1043, 1076, 1105, 1146, 1162, 1191, 1216, 1248, 1269, 1330, 1350, 1369, 1381, 1402, 1425, 1464, 1489, 1564, 1602, 1626, 1654, 1686, 1721, 1762, 1780, 1807, 1835, 1897, 1950, 2002, 2023, 2109, 2127, 2218, 2250, 2264, 2315, 2343, 2381, 2437, 2498, 2528, 2555, 2583, 2677, 2814, 2886, 3030, 3162, 3197, 3244, 3318, 3356, 3374, 3449, 3531, 3566, 3635, 3696, 3770, 3797, 3832, 3891, 3958, 4177, 4322, 4347, 4371, 4405, 4435, 4466, 4493], '(373)': [478], 'Google': [479, 556, 583, 611, 630, 670, 700, 718, 737, 758, 785, 817, 850, 872, 920, 973, 992, 1016, 1045, 1078, 1107, 1148, 1164, 1193, 1218, 1250, 1271, 1332, 1352, 1371, 1383, 1404, 1427, 1466, 1491, 1566, 1604, 1628, 1656, 1688, 1723, 1764, 1782, 1809, 1837, 1899, 1952, 2004, 2025, 2111, 2129, 2220, 2252, 2266, 2317, 2345, 2383, 2439, 2500, 2530, 2557, 2585, 2679, 2816, 2888, 3032, 3164, 3199, 3246, 3320, 3358, 3376, 3451, 3533, 3568, 3637, 3698, 3772, 3799, 3834, 3858, 3875, 3893, 3960, 4179, 4324, 4349, 4373, 4407, 4437, 4468, 4495], 'Scholar).': [480, 818, 921, 1428, 1492, 1567, 1838, 1900, 1953, 2221, 2267, 2440, 2501, 2531, 2558, 2586, 2680, 2889, 3033, 3200, 3377, 3452, 3534, 3638, 3894, 4325], 'considered': [483, 2154], 'critical': [486, 3993], 'inducing': [488, 3114], 'helper': [490], '(Th)': [491], '3The': [492], 'abbreviations': [493], 'used': [494, 2140], 'are:': [495], 'Th,': [496], 'helper;': [498], 'cells;': [508], 'HUVEC,': [509], 'umbilical': [511], 'vein': [512], 'cell;': [514], 'NK,': [515], 'natural': [516], 'killer.': [517], '2-type': [518], 'responses': [520], 'like': [521, 938, 3480], 'immunity': [522], 'against': [523], 'nematodes': [524], 'allergic': [526, 1920], 'diseases': [527, 2699], 'with': [528, 1958, 1963, 2597, 2696, 2832, 3460, 3487, 3702, 4183, 4196], 'IL-3,': [529], 'IL-4,': [530, 1737], 'and/or': [531, 1526], 'IL-13': [532], 'Th2': [534, 1582], '(2Chackerian': [536, 1446], 'A.A.': [537, 1447], 'Oldham': [538, 636, 1298, 1448, 1532, 2186, 2283, 2645, 2782, 2854, 2998, 3130], 'E.R.': [539, 1449], 'Murphy': [540, 640, 1115, 1302, 1450, 1536, 2190, 2287, 2649, 2786, 2858, 3002, 3134], 'E.E.': [541, 1451], 'Schmitz': [542, 1452], 'Pflanz': [544, 1454], 'S.': [545, 592, 618, 681, 746, 794, 954, 980, 1062, 1068, 1083, 1097, 1120, 1233, 1339, 1357, 1374, 1386, 1407, 1455, 1477, 1665, 1706, 1752, 1828, 2070, 2417, 2419, 2486, 3522, 3559, 3628, 3689, 3783, 3802, 3812, 3839, 3853, 4378, 4390, 4392, 4417, 4441], 'Kastelein': [546, 656, 1318, 1456, 1552, 2206, 2303, 2665, 2802, 2874, 3018, 3150], 'R.A.': [547, 657, 1319, 1457, 1553, 2207, 2304, 2666, 2803, 2875, 3019, 3151, 3553, 3622, 3683], 'Immunol.': [549, 604, 693, 711, 773, 865, 966, 1009, 1141, 1181, 1211, 1243, 1459, 1621, 1644, 1716, 1775, 1797, 1887, 2244, 3561, 3630, 3691, 3871, 4366, 4461], '2007;': [550, 712, 844, 1039, 1072, 1460, 1622, 1776, 1831], '179:': [551, 713, 1461, 1623, 1777], '2551-2555Crossref': [552, 1462], '(432)': [555, 1465], 'Scholar,': [557, 584, 612, 631, 701, 759, 786, 851, 873, 974, 993, 1017, 1046, 1079, 1108, 1149, 1165, 1194, 1219, 1251, 1333, 1353, 1372, 1384, 1405, 1467, 1657, 1765, 1783, 1810, 2112, 2253, 2346, 3321, 3359, 3773, 3800, 3835, 3859, 3876], '3Guo': [558], 'L.': [559, 1021, 1027, 1029, 2053], 'Wei': [560], 'Zhu': [562], 'Liao': [564], 'W.': [565, 571, 3822, 3880], 'Leonard': [566], 'W.J.': [567], 'Zhao': [568], 'K.': [569, 590, 602, 679, 691, 767, 796, 802, 804, 806, 952, 964, 1052, 1081, 1085, 1091, 1095, 1235, 1237, 1239, 1411, 1638, 1667, 1673, 1675, 1677, 1708, 1710, 1712, 1791, 1818, 1981, 2088, 2096, 2364, 3227, 3339, 3432, 3545, 3551, 3555, 3614, 3620, 3624, 3675, 3681, 3685, 4453, 4455], 'Paul': [570], 'Proc.': [572, 1034, 1360, 2334, 3188, 3309, 3788, 3949, 4168, 4426, 4484], 'Natl.': [573, 1035, 1361, 2335, 3189, 3310, 3789, 3950, 4169, 4427, 4485], 'Acad.': [574, 1036, 1362, 2258, 2336, 3190, 3311, 3790, 3951, 4170, 4428, 4486], 'Sci.': [575, 1037, 1363, 2259, 2337, 2523, 3191, 3312, 3791, 3952, 4171, 4429, 4487], 'U.S.A.': [576, 1038, 1364, 2338, 3192, 3313, 3792, 3953, 4172, 4430, 4488], '2009;': [577, 624, 726, 752, 986, 1142, 1182, 1758, 1888, 2339, 2372, 3193, 3235, 3314, 3347, 3365, 3440, 3527, 3562, 3631, 3692], '106:': [578, 2340, 3194, 3315], '13463-13468Crossref': [579], '(305)': [582], '4Kondo': [585], 'Y.': [586, 639, 675, 948, 1060, 1301, 1535, 1822, 2189, 2286, 2423, 2648, 2785, 2857, 3001, 3133, 3516, 3869, 3934, 4153], 'Yoshimoto': [587, 676, 949], 'Yasuda': [589, 678, 951], 'Futatsugi-Yumikura': [591, 680, 953], 'Morimoto': [593, 682, 955], 'Hayashi': [595, 684, 957], 'N.': [596, 620, 685, 748, 958, 982, 1023, 1054, 1122, 1129, 1153, 1754, 1816, 2080, 3547, 3616, 3677, 3865, 3942, 4161, 4357], 'Hoshino': [597, 686, 959], 'Fujimoto': [599, 688, 961], 'Nakanishi': [601, 690, 963, 1090], 'Int.': [603, 692, 864, 965], '2008;': [605, 694, 774, 811, 866, 967, 1158, 1244, 1485, 1645, 1682, 1717, 1798, 2246], '20:': [606, 695, 867, 968], '791-800Crossref': [607, 696, 969], '(404)': [610, 699, 972], '5Pecaric-Petkovic': [613, 975], 'Didichenko': [615, 743, 977, 1749], 'S.A.': [616, 744, 978, 1750], 'Kaempfer': [617, 745, 979, 1751], 'Spiegl': [619, 747, 981, 1753], 'Dahinden': [621, 749, 983, 1755], 'C.A.': [622, 750, 984, 1756, 1942, 2255, 3759, 3785, 4481], 'Blood.': [623, 751, 985, 1757], '113:': [625, 753, 987, 1759], '1526-1534Crossref': [626, 754, 988, 1760], '(344)': [629, 757, 991, 1763], '6Schmitz': [632], 'Owyang': [634, 1296, 1530, 2184, 2281, 2643, 2780, 2852, 2996, 3128], 'A.': [635, 1001, 1124, 1231, 1297, 1337, 1531, 1704, 2185, 2282, 2644, 2781, 2853, 2997, 3129, 3824, 3845, 3867, 4338, 4415, 4443, 4451, 4479], 'E.': [637, 641, 1204, 1299, 1303, 1533, 1537, 2118, 2187, 2191, 2284, 2288, 2646, 2650, 2783, 2787, 2855, 2859, 2999, 3003, 3131, 3135, 3549, 3618, 3679, 4353, 4386, 4388], 'Song': [638, 1300, 1534, 2188, 2285, 2647, 2784, 2856, 3000, 3132], 'McClanahan': [642, 1304, 1538, 2192, 2289, 2651, 2788, 2860, 3004, 3136], 'T.K.': [643, 1305, 1539, 2193, 2290, 2652, 2789, 2861, 3005, 3137], 'Zurawski': [644, 1306, 1540, 2194, 2291, 2653, 2790, 2862, 3006, 3138], 'Moshrefi': [646, 1308, 1542, 2196, 2293, 2655, 2792, 2864, 3008, 3140], 'Qin': [648, 1310, 1544, 2198, 2295, 2657, 2794, 2866, 3010, 3142], 'Li': [650, 1312, 1546, 2200, 2297, 2659, 2796, 2868, 3012, 3144], 'X.': [651, 1313, 1547, 2201, 2298, 2660, 2797, 2869, 3013, 3145], 'Gorman': [652, 1314, 1548, 2202, 2299, 2661, 2798, 2870, 3014, 3146], 'D.M.': [653, 1315, 1549, 2203, 2300, 2662, 2799, 2871, 3015, 3147], 'Bazan': [654, 1316, 1550, 2204, 2301, 2663, 2800, 2872, 3016, 3148], 'J.F.': [655, 1317, 1551, 2205, 2302, 2664, 2801, 2873, 3017, 3149], 'Immunity.': [658, 725, 1320, 1554, 2208, 2305, 2371, 2667, 2804, 2876, 3020, 3152, 3234, 3346, 3364, 3439, 3760], '2005;': [659, 1321, 1555, 2019, 2209, 2306, 2433, 2551, 2668, 2805, 2877, 3021, 3153, 3761], '23:': [660, 1322, 1556, 2210, 2307, 2669, 2806, 2878, 3022, 3154], '479-490Abstract': [661, 1323, 1557, 2211, 2308, 2670, 2807, 2879, 3023, 3155], '(2763)': [669, 1331, 1565, 2219, 2316, 2678, 2815, 2887, 3031, 3163], 'Scholar),': [671, 719, 738, 1629, 1689, 2005, 2026, 2318, 3165, 3961, 4180, 4350, 4374, 4408, 4438, 4469], 'mast': [672, 1610, 3583], '(4Kondo': [674, 947], '7Allakhverdi': [702, 1766], 'Z.': [703, 1613, 1767, 1863, 1975, 2425], 'Smith': [704, 862, 1482, 1614, 1768, 1866], 'D.E.': [705, 863, 1483, 1615, 1769, 1867], 'Comeau': [706, 854, 1616, 1770, 1864], 'M.R.': [707, 855, 1617, 1771, 1865, 3806, 4359], 'Delespesse': [708, 1618, 1772, 1882], '2051-2054Crossref': [714, 1624, 1778], '(409)': [717, 1627, 1781], 'basophils': [720, 1692], '(8Sullivan': [721], 'B.M.': [722], 'Locksley': [723], 'R.M.': [724], '30:': [727, 1213], '12-20Abstract': [728], '(95)': [736], 'eosinophils': [740, 1630], '(5Pecaric-Petkovic': [741, 1747], '9Cherry': [760, 1784], 'W.B.': [761, 1632, 1785], 'Yoon': [762, 856, 1633, 1786, 3756], 'Bartemes': [764, 1172, 1635, 1788], 'K.R.': [765, 1173, 1636, 1789], 'Iijima': [766, 1637, 1790], 'Kita': [768, 1176, 1639, 1792], 'H.': [769, 798, 800, 999, 1056, 1064, 1171, 1177, 1227, 1640, 1669, 1671, 1700, 1793, 1814, 1824, 2009, 2072, 2082, 2090, 2431, 3514, 3518, 3520, 3557, 3626, 3687, 3861, 4421, 4449, 4457, 4459], 'Allergy': [771, 1179, 1642, 1795, 1885], 'Clin.': [772, 1180, 1643, 1796, 1886, 4364], '121:': [775, 1646, 1799], '1484-1490Abstract': [776, 1647, 1800], '(395)': [784, 1655, 1808], '10Suzukawa': [787, 1658], 'Koketsu': [789, 1224, 1660, 1697], 'R.': [790, 861, 1208, 1225, 1355, 1661, 1698, 1983, 1991, 2055, 2094, 2102, 2478, 3810, 3837, 3841, 3884], 'Iikura': [791, 1057, 1222, 1662, 1695], 'Nakae': [793, 1067, 1232, 1664, 1705, 1827, 3558, 3627, 3688], 'Matsumoto': [795, 1666], 'Nagase': [797, 1226, 1668, 1699], 'Saito': [799, 1063, 1670, 1823, 3556, 3625, 3686], 'Matsushima': [801, 1234, 1672, 1707], 'Ohta': [803, 1236, 1674, 1709], 'Yamamoto': [805, 1238, 1676, 1711], 'Yamaguchi': [807, 1240, 1678, 1713, 4446], 'Lab.': [809, 1680, 1829], 'Invest.': [810, 1681, 1830], '88:': [812, 1683], '1245-1253Crossref': [813, 1684], '(165)': [816, 1687], 'also': [820, 924, 3110, 4282], 'induces': [821, 2387, 2458], 'non-Th2': [822], 'cytokines': [824, 1733, 1861, 2919, 3116, 3742, 4220, 4329], 'such': [825, 1500, 2448, 2920, 3743, 4330, 4523], 'TNFα,': [827, 2928], 'IL-1β,': [828], 'or': [829, 1284, 3597], 'IL-6': [830], '(11Moulin': [831], 'D.': [832, 836, 859, 886, 997, 1137, 1475, 1479, 1593, 1869, 1993, 2057, 2427, 4473], 'Donzé': [833], 'O.': [834], 'Talabot-Ayer': [835, 1478], 'Mézin': [837], 'Palmer': [839, 2240], 'Gabay': [841, 1480, 2242], 'C.': [842, 1133, 1151, 1229, 1481, 1702, 2243, 2331, 2358, 3185, 3221, 3306, 3333, 3426, 4411, 4413, 4529, 4531], 'Cytokine.': [843, 1484, 3827], '40:': [845], '216-225Crossref': [846], '(263)': [849, 1351], '12Smithgall': [852], 'M.D.': [853, 1473], 'B.R.': [857], 'Kaufman': [858, 2547], 'Armitage': [860], '1019-1030Crossref': [868], '(480)': [871], '13Verri': [874], 'Jr.,': [875, 2067], 'W.A.': [876], 'Souto': [877], 'F.O.': [878], 'Vieira': [879], 'S.M.': [880], 'Almeida': [881], 'S.C.': [882], 'Fukada': [883], 'S.Y.': [884, 3753], 'Xu': [885, 996, 1136, 1592], 'Alves-Filho': [887], 'J.C.': [888, 3818], 'Cunha': [889, 909], 'T.M.': [890], 'Guerrero': [891], 'A.T.': [892], 'Mattos-Guimaraes': [893], 'R.B.': [894, 3814], 'Oliveira': [895], 'F.R.': [896], 'Teixeira': [897], 'M.M.': [898], 'Silva': [899], 'J.S.': [900], 'McInnes': [901, 1134], 'I.B.': [902, 1135], 'Ferreira': [903], 'S.H.': [904, 3751, 3787, 4483], 'Louzada-Junior': [905], 'Liew': [907, 1006, 1138], 'F.Y.': [908, 1007, 1139], 'F.Q.': [910], 'Ann.': [911, 2016, 2256], 'Rheum.': [912, 1997, 2017, 2104, 2122, 3886], 'Dis.': [913, 2018], '2010;': [914], '69:': [915], '1697-1703Crossref': [916], '(203)': [919], 'It': [922, 1568, 2222], 'has': [923, 1569, 1841, 2223, 2270, 2726, 3167, 3905, 3917, 4133], 'been': [925, 1570, 1842, 2224, 2271, 2727, 3168], 'reported': [926, 1843, 2844, 3169, 3248, 3570], 'act': [930], 'transcription': [936], 'IL-1β': [939, 1957, 2138, 2150, 2235, 4409, 4525], 'mobility': [942], 'group': [943], 'B1': [945], '(HMGB1)': [946], '14Brint': [994], 'E.K.': [995], 'Liu': [998, 1874], 'Dunne': [1000], 'McKenzie': [1002, 1260], 'A.N.': [1003, 1261], "O'Neill": [1004], 'L.A.': [1005], 'Nat.': [1008, 2576], '2004;': [1010, 1598, 1946, 2123, 2579], '5:': [1011, 2580], '373-379Crossref': [1012], '(431)': [1015], '15Carriere': [1018], 'V.': [1019, 1589, 4380], 'Roussel': [1020], 'Ortega': [1022, 1152], 'Lacorre': [1024], 'D.A.': [1025], 'Americh': [1026], 'Aguilar': [1028], 'Bouche': [1030], '104:': [1040], '282-287Crossref': [1041], '(761)': [1044], '16Ho': [1047], 'L.H.': [1048], 'Ohno': [1049, 1819, 3539, 3669], 'Oboki': [1051, 1817, 3544, 3613, 3674], 'Kajiwara': [1053, 1815, 3546, 3615, 3676], 'Suto': [1055, 1813], 'Okayama': [1059, 1821], 'Akira': [1061, 1096], 'Galli': [1065, 1825], 'S.J.': [1066, 1826, 2370, 3233, 3345, 3438], 'Leukocyte': [1070], 'Biol.': [1071, 4394], '82:': [1073], '1481-1490Crossref': [1074], '(241)': [1077], '17Hoshino': [1080], 'Kashiwamura': [1082], 'Kuribayashi': [1084], 'Kodama': [1086], 'Tsujimura': [1088], 'Matsuyama': [1092, 3515], 'Takeda': [1094], 'Exp.': [1099, 1263, 4365], 'Med.': [1100, 1264], '1999;': [1101, 4431], '190:': [1102], '1541-1548Crossref': [1103], '(163)': [1106], '18Kurowska-Stolarska': [1109], 'Stolarski': [1111], 'B.': [1112, 1126, 1967, 1985, 1989, 3851, 3882, 4313, 4384], 'Kewin': [1113], 'Corrigan': [1117], 'C.J.': [1118], 'Ying': [1119], 'Pitman': [1121], 'Mirchandani': [1123], 'Rana': [1125], 'van': [1127], 'Rooijen': [1128], 'Shepherd': [1130], 'McSharry': [1132], '183:': [1143, 3563, 3632, 3693], '6469-6477Crossref': [1144], '(533)': [1147], '19Moussion': [1150], 'PLoS': [1156], 'One.': [1157], '3:': [1159], 'e3331Crossref': [1160], '(877)': [1163], '20Rank': [1166], 'M.A.': [1167], 'Kobayashi': [1168], 'Kozaki': [1170], 'Squillace': [1174], 'D.L.': [1175, 2100], '123:': [1183, 1889], '1047-1054Abstract': [1184], '(298)': [1192], '21Senn': [1195], 'K.A.': [1196], 'McCoy': [1197], 'K.D.': [1198], 'Maloy': [1199], 'K.J.': [1200, 1877], 'Stark': [1201], 'Fröhli': [1203], 'Rülicke': [1205], 'Klemenz': [1207], 'Eur.': [1209], '2000;': [1212, 1265, 2524], '1929-1938Crossref': [1214], '(50)': [1217], '22Suzukawa': [1220], 'Tamura': [1228, 1701], 'Komiya': [1230, 1703], '181:': [1245, 1718], '5981-5989Crossref': [1246, 1719], '(253)': [1249, 1722], '23Townsend': [1252], 'M.J.': [1253, 1591], 'Fallon': [1254], 'P.G.': [1255], 'Matthews': [1256], 'D.J.': [1257, 1390, 2092, 3808], 'Jolin': [1258], 'H.E.': [1259], '191:': [1266], '1069-1076Crossref': [1267], '(407)': [1270], 'Scholar).IL-33': [1272], 'for': [1276, 1434, 1572, 2141, 2231, 2405, 3577, 4512], '(also': [1278], 'known': [1279, 1727, 2225, 2841, 2900, 4283], 'IL-1RL1,': [1281], 'DER4,': [1282], 'Fit-1,': [1283], 'T1),': [1285], 'an': [1291, 2402, 2406, 3063, 3927], 'orphan': [1292], '(6Schmitz': [1294, 1528, 2182, 2279, 2641, 2778, 2850, 2994, 3126], '24Bergers': [1334], 'Reikerstorfer': [1336], 'Braselmann': [1338], 'Graninger': [1340], 'Busslinger': [1342], 'EMBO': [1344], '1994;': [1346, 4343], '13:': [1347], '1176-1188Crossref': [1348], '25Klemenz': [1354], 'Hoffmann': [1356], 'Werenskiold': [1358], 'A.K.': [1359], '1989;': [1365, 1377], '86:': [1366], '5708-5712Crossref': [1367], '(150)': [1370], '26Tominaga': [1373], 'FEBS': [1375, 4341], 'Lett.': [1376, 4342], '258:': [1378], '301-304Crossref': [1379], '(320)': [1382], '27Tominaga': [1385], 'Jenkins': [1387], 'N.A.': [1388], 'Gilbert': [1389], 'Copeland': [1391], 'N.G.': [1392, 2074], 'Tetsuka': [1393, 1416], 'Biochim.': [1395, 1418], 'Biophys.': [1396, 1419, 3524], 'Acta.': [1397, 1420], '1991;': [1398], '1090:': [1399], '1-8Crossref': [1400], '(71)': [1403], '28Tominaga': [1406], 'Yokota': [1408], 'Yanagisawa': [1410], 'Tsukamoto': [1412], 'Takagi': [1414], '1992;': [1421], '1171:': [1422], '215-218Crossref': [1423], '(54)': [1426], 'Thus,': [1429, 2587, 4187, 4504], 'complex': [1433, 1495], 'signaling': [1435, 1498], 'composed': [1437], '29Palmer': [1468], 'Lipsky': [1470], 'B.P.': [1471], 'Smithgall': [1472], 'Meininger': [1474], 'Siu': [1476], '42:': [1486], '358-364Crossref': [1487], '(140)': [1490], 'This': [1493, 2161, 2400, 2532, 4100, 4230], 'activates': [1496, 4205], 'downstream': [1497], 'molecules': [1499], 'activation': [1513, 2952], '1': [1515, 3472], '(AP-1)': [1516], 'through': [1517, 4208], 'kinase,': [1520], 'TNF': [1521], '6': [1524], '(TRAF6),': [1525], 'MAPKs': [1527], 'established': [1571], 'several': [1573, 2388, 2512, 2958, 4328], 'years': [1574], 'selective': [1579], 'marker': [1580, 2144], 'mouse': [1585, 2927, 2933, 3718, 4084, 4197], '(30Trajkovic': [1588], 'Sweet': [1590], 'Cytokine': [1594], 'Growth': [1595], 'Factor': [1596], 'Rev.': [1597, 2245, 2577], '15:': [1599], '87-95Crossref': [1600], '(144)': [1603], 'Scholar)': [1605, 1724, 2130, 3247, 3569, 3699, 4496], 'on': [1609, 2690, 2975, 3096, 3203, 3660, 4017], '(7Allakhverdi': [1612], '(9Cherry': [1631], 'even': [1691, 2506], '(22Suzukawa': [1693], 'without': [1725, 3503], 'ligand.': [1728], 'These': [1729], 'produce': [1731], 'chemokines,': [1735], 'including': [1736, 1923, 2514, 2541], 'IL-5,': [1738], 'IL-6,': [1739, 2929], 'IL-13,': [1740], 'IL-8': [1742, 2923, 4332], 'under': [1743], 'stimulation': [1744], '31Iikura': [1811], '87:': [1832], '971-978Crossref': [1833], '(312)': [1836], 'Recently,': [1839], 'it': [1840, 2172, 2269, 3166, 4300], 'circulating': [1845], 'CD34+': [1846], 'hematopoietic': [1847], 'progenitors': [1848], 'responded': [1852], 'releasing': [1856], 'levels': [1858], 'Th2-associated': [1860, 1909, 2847], '(32Allakhverdi': [1862], 'Toy': [1868], 'Endam': [1870], 'L.M.': [1871], 'Desrosiers': [1872], 'Y.J.': [1875], 'Howie': [1876], 'Denburg': [1878], 'J.A.': [1879, 3944, 4163], 'Gauvreau': [1880], 'G.M.': [1881], '472-478Abstract': [1890], '(191)': [1898], 'Such': [1901], 'observations': [1902], 'suggest': [1903], 'potential': [1904, 4509], 'roles': [1905, 1935], 'responses,': [1911], 'seems': [1914], 'closely': [1917], 'related': [1918], 'diseases,': [1922, 2513], 'asthma': [1924], 'atopic': [1926], 'dermatitis.IL-1': [1927], 'members': [1929], 'play': [1930], 'variety': [1932], 'pathological': [1934], 'autoimmune': [1937, 2698], 'disorders': [1940], '(33Dinarello': [1941], 'Curr.': [1943], 'Opin.': [1944], 'Pharmacol.': [1945], '4:': [1947], '378-385Crossref': [1948], '(174)': [1951], 'A': [1954, 3070], 'blockade': [1955], 'IL-1R': [1959], 'antagonist': [1960], 'patients': [1962, 2695], 'rheumatoid': [1964], 'arthritis': [1965], '(34Bresnihan': [1966], 'Alvaro-Gracia': [1968], 'J.M.': [1969, 3940, 4159, 4382], 'Cobby': [1970], 'Doherty': [1972], 'Domljan': [1974], 'Emery': [1976], 'Nuki': [1978], 'Pavelka': [1980], 'Rau': [1982], 'Rozman': [1984], 'Watt': [1986], 'I.': [1987, 2041, 2421, 2476], 'Williams': [1988], 'Aitchison': [1990], 'McCabe': [1992], 'Musikic': [1994], 'Arthritis': [1996, 2103, 2121, 3885], '1998;': [1998, 2260, 3872], '41:': [1999], '2196-2204Crossref': [2000], '(927)': [2003], 'ankylosing': [2006], 'spondylitis': [2007], '(35Haibel': [2008], 'Rudwaleit': [2010], 'Listing': [2012], 'Sieper': [2014], '64:': [2020], '296-298Crossref': [2021], '(187)': [2024], 'mutations': [2028], 'NACHT,': [2031], 'LRR,': [2032], 'PYD': [2034], 'domain-containing': [2035], '(NALP3)': [2038], 'gene': [2039, 2415], '(36Aksentijevich': [2040], 'Nowak': [2042], 'Mallah': [2044], 'Chae': [2046], 'J.J.': [2047, 2098], 'Watford': [2048], 'W.T.': [2049], 'Hofmann': [2050], 'S.R.': [2051], 'Stein': [2052], 'Russo': [2054], 'Goldsmith': [2056], 'Dent': [2058], 'Rosenberg': [2060], 'H.F.': [2061], 'Austin': [2062], 'Remmers': [2064], 'E.F.': [2065], 'Balow': [2066], 'J.E.': [2068], 'Rosenzweig': [2069], 'Komarow': [2071], 'Shoham': [2073], 'Wood': [2075], 'Jones': [2077], 'Mangra': [2079], 'Carrero': [2081], 'Adams': [2083], 'B.S.': [2084], 'Moore': [2085], 'T.L.': [2086], 'Schikler': [2087], 'Hoffman': [2089], 'Lovell': [2091], 'Lipnick': [2093], 'Barron': [2095], "O'Shea": [2097], 'Kastner': [2099], 'Goldbach-Mansky': [2101], '2002;': [2105, 3793, 3828], '46:': [2106], '3340-3348Crossref': [2107], '(588)': [2110], '37Hawkins': [2113], 'P.N.': [2114], 'Lachmann': [2115], 'H.J.': [2116], 'Aganna': [2117], 'McDermott': [2119], 'M.F.': [2120], '50:': [2124], '607-612Crossref': [2125], '(449)': [2128], 'relieves': [2131], 'symptoms': [2133], 'these': [2135, 3396, 3642], 'diseases.': [2136], 'Therefore,': [2137], 'immunological': [2143], 'diseases.IL-33,': [2147], 'similarly': [2148], 'IL-18,': [2152], 'formed': [2157, 2444], 'intracellularly': [2158], 'pro-IL-33.': [2160], 'pro-form': [2162], 'does': [2163, 3279], 'have': [2165, 3398], 'signal': [2167, 2820, 2911, 3908, 3920, 4142], 'peptide': [2168, 3909, 3921, 4143], 'secreted;': [2171], 'released': [2174, 3264, 3588], 'extracellularly': [2175], 'mature': [2178, 2389, 2837, 3065, 3078, 3495, 4044, 4055, 4058, 4069, 4105, 4226, 4237], 'after': [2180], 'caspases': [2228, 2323, 3251], 'are': [2229, 2443, 2561, 3575, 3731, 3896], 'necessary': [2230, 4263], '(38Arend': [2238], 'W.P.': [2239], '223:': [2247], '20-38Crossref': [2248], '(634)': [2251], '39Dinarello': [2254], 'N.Y.': [2257], '856:': [2261], '1-11Crossref': [2262], '(419)': [2265], 'Although': [2268, 2890, 3709, 4244], 'suggested': [2272, 2966, 3272, 3475], 'processed': [2276, 2503, 3058, 4111], 'exact': [2320], 'role': [2321, 2591, 2704, 2947], 'biology': [2326], 'still': [2327], 'remains': [2328], 'controversial': [2329, 2956], '(40Cayrol': [2330, 3184, 3305], '9021-9026Crossref': [2341, 3195, 3316], '(529)': [2344, 2382, 3198, 3245, 3319, 3357, 3450], '41Lüthi': [2347, 3322], 'A.U.': [2348, 3211, 3323, 3416], 'Cullen': [2349, 3212, 3324, 3417], 'S.P.': [2350, 3213, 3325, 3418], 'McNeela': [2351, 3214, 3326, 3419], 'E.A.': [2352, 3215, 3327, 3420], 'Duriez': [2353, 3216, 3328, 3421], 'P.J.': [2354, 3217, 3329, 3422], 'Afonina': [2355, 3218, 3330, 3423], 'I.S.': [2356, 3219, 3331, 3424], 'Sheridan': [2357, 3220, 3332, 3425], 'Brumatti': [2359, 3222, 3334, 3427], 'Taylor': [2361, 3224, 3336, 3429], 'R.C.': [2362, 3225, 3337, 3430], 'Kersse': [2363, 3226, 3338, 3431], 'Vandenabeele': [2365, 3228, 3340, 3433], 'Lavelle': [2367, 3230, 3342, 3435], 'E.C.': [2368, 3231, 3343, 3436], 'Martin': [2369, 3232, 3344, 3437], '31:': [2373, 3236, 3348, 3366, 3441], '84-98Abstract': [2374, 3237, 3349, 3442], 'Scholar).Alternative': [2384], 'splicing,': [2385], 'mRNAs': [2390, 2504], 'pre-mRNA,': [2393], 'frequent': [2396], 'process': [2397, 2533, 3252], 'eukaryotes.': [2399], 'efficient': [2403], 'method': [2404], 'organism': [2407], 'form': [2409, 4106], 'various': [2410, 2538, 2751], 'proteins': [2411, 2472, 3046, 3464], 'single': [2414], '(42Stamm': [2416], 'Ben-Ari': [2418], 'Rafalska': [2420], 'Tang': [2422], 'Zhang': [2424], 'Toiber': [2426], 'Thanaraj': [2428], 'T.A.': [2429, 2519, 3938, 3948, 4157, 4167], 'Soreq': [2430], 'Gene.': [2432], '344:': [2434], '1-20Crossref': [2435], '(674)': [2438], 'Numerous': [2441], 'transcripts': [2442], 'cis-regulatory': [2446], 'elements': [2447], 'promoter,': [2451], 'enhancer,': [2452], 'repressor': [2454], 'control.': [2455], 'Alternative': [2456], 'splicing': [2457, 2566, 3929, 3969, 3985], 'structural': [2459], 'differences': [2460], 'translated': [2463, 2987], 'proteins,': [2464], 'leads': [2466], 'functional': [2468, 2602], 'changes': [2469], 'produced': [2471], '(43Kriventseva': [2473], 'E.V.': [2474], 'Koch': [2475], 'Apweiler': [2477], 'Vingron': [2479], 'Bork': [2481], 'Gelfand': [2483], 'M.S.': [2484], 'Sunyaev': [2485], 'Trends': [2487], 'Genet.': [2488, 2578], '19:': [2490], '124-128Abstract': [2491], '(179)': [2499], 'Alternatively': [2502], 'can': [2505, 2595], 'lead': [2507], 'induction': [2510, 2916], 'cancers': [2515], '(44Philips': [2516], 'A.V.': [2517], 'Cooper': [2518], 'Cell.': [2520], 'Mol.': [2521], 'Life': [2522], '57:': [2525], '235-249Crossref': [2526], '(108)': [2529], 'tightly': [2535], 'regulated': [2536, 2569], 'stress': [2539, 2544], 'conditions,': [2540], 'endoplasmic': [2542], 'reticulum': [2543], '(45Schröder': [2545], 'R.J.': [2548], 'Mutat.': [2549], 'Res.': [2550, 3525], '569:': [2552], '29-63Crossref': [2553], '(1369)': [2556], 'Furthermore,': [2559], 'there': [2560, 3710], 'many': [2562], 'reports': [2563], 'suggesting': [2564], 'alternative': [2565, 3928], 'efficiently': [2568, 4148], 'accomplish': [2571], 'specialized': [2572], 'tasks': [2573], '(46Ast': [2574], '773-782Crossref': [2581], '(427)': [2584], 'characterizing': [2588], 'variants': [2594, 3730, 3738], 'help': [2596], 'their': [2601], 'application': [2603], 'diseases.In': [2606], 'newly': [2612], '(spIL-33),': [2617, 2723], 'its': [2624, 2904, 3591, 4012], 'coding': [2625], 'region.': [2626], 'Interestingly,': [2627, 3034], 'deleted': [2629], 'region': [2632, 3970, 3994], 'contains': [2635], 'site': [2640, 2773, 3276, 3284, 3300, 4000], 'further': [2688, 4260], 'study': [2689, 2963, 3202, 3474], 'different': [2697, 4051, 4277], 'will': [2700], 'reveal': [2701], 'precise': [2703], 'responses.DISCUSSIONIn': [2709], 'first': [2713, 2962], 'demonstrated': [2714], 'isoform': [2717, 4132, 4145], 'discovery': [2736], 'carried': [2740, 3658], 'out': [2741, 3659], 'while': [2742], 'attempted': [2744], 'isolate': [2746], 'lines.': [2754], 'found': [2756], 'revealed': [2762], 'lack': [2764], 'at': [2768, 3282, 3290, 3725], 'predicted': [2770, 2980], '(Figs.': [2774], '1B': [2775], '2)': [2777], 'Scholar).The': [2817], 'molecular': [2818], 'structure,': [2819], 'transduction,': [2821], 'studied': [2829], 'compared': [2831], 'IL-33.': [2838], 'previously': [2840], '42': [2894], 'amino': [2895, 2971, 3292, 3391, 3727, 3911, 3923], 'acids': [2896], '(Arg74–Gly115)': [2897], '(Fig.': [2902, 3068, 3106, 3117, 4020, 4041, 4228], '2),': [2903], 'ability': [2905], 'activate': [2907], 'typical': [2909], 'pathways': [2912], 'resulted': [2913], 'HMC': [2925], 'MIP-2': [2931], '(FIGURE': [2937, 4088], '4,': [2938, 3069, 3118, 4006, 4021, 4089], 'FIGURE': [2939, 2941, 2943, 2945, 4090, 4092, 4094, 4096, 4098], '5,': [2940, 4091], '6,': [2942, 4093], '7,': [2944, 4095], '8).The': [2946], 'previous': [2959], 'studies.': [2960], 'cleaves': [2969], 'acid': [2972, 3293, 3392, 3728], 'residue': [2973], '(Asp110–Ser111)': [2974, 3287], 'pro-IL-33,': [2977, 3261, 3492, 4513], 'incubation': [2983], 'vitro': [2986], 'rather': [2989, 3289], 'than': [2990, 4181], 'our': [3035, 3456, 4053], 'results': [3036, 3180, 3643], 'Fig.': [3038, 4005], '4A': [3039], 'showed': [3040, 4027], 'but': [3052, 3288, 3967, 4074], 'pro-IL-18': [3054], 'became': [3062], '18-kDa': [3066], 'B).': [3072], 'Moreover,': [3073], 'stimulated': [3080], 'cytokines,': [3089], 'independent': [3092], '4A)': [3107], 'C': [3119, 4022], 'D).Contrary': [3121], 'initial': [3124], 'report': [3125, 3667], 'full-length': [3171], 'processing': [3177, 3205, 3477, 3656, 4304, 4510], 'inactivation': [3183, 3259], 'Luthi': [3207], 'et': [3208, 3540, 3670], 'al.': [3209, 3541, 3671], '(41Lüthi': [3210, 3415], 'apoptotic': [3250, 3255], 'resulting': [3257], 'whereas': [3262, 3664], 'necrotic': [3266], 'spontaneously': [3269], 'active.': [3270], 'They': [3271], 'occur': [3281], 'initially': [3285], 'residues': [3294, 3393], 'Asp178–Gly179,': [3295], 'consensus': [3299], 'caspase-3': [3304, 3379], '50Lamkanfi': [3360], 'Dixit': [3362], 'V.M.': [3363], '5-7Abstract': [3367], '(93)': [3375], 'Apoptotic': [3378], '-7': [3381], 'destroy': [3382], 'Asp178–Gly179.': [3394], 'Nevertheless,': [3395], 'studies': [3397], 'performed': [3399, 3459, 3701], 'vitro;': [3401], 'shown': [3409, 3484, 4003], 'only': [3411, 3722], 'NFκ-B': [3412], 'luciferase': [3413], 'assay': [3414], 'Unlike': [3453, 3982], 'experiments': [3457], 'HPLC-purified': [3461], '(endotoxin': [3465], 'level': [3466], 'below': [3467], '0.3': [3468], 'enzyme': [3469, 4511], 'units': [3470], 'per': [3471], 'μg).Another': [3473], 'calpain-dependent': [3476, 3654], 'IL-1α,': [3481], 'treatment': [3486], 'calcium': [3488], 'ionophore.': [3489], 'Calpain': [3490], 'processes': [3491, 4327, 4516], 'produces': [3494], 'epithelial': [3499], 'proving': [3504], 'calpain-cleaved': [3509], '(51Hayakawa': [3511], 'Hayakawa': [3513], 'Tamemoto': [3517], 'Okazaki': [3519], 'Tominaga': [3521], 'Biochem.': [3523], 'Commun.': [3526], '387:': [3528], '218-222Crossref': [3529], '(61)': [3532], 'Contrary': [3535], 'result,': [3538], '(52Ohno': [3542, 3611, 3672], 'Morii': [3548, 3617, 3678], 'Aozasa': [3550, 3619, 3680], 'Flavell': [3552, 3621, 3682], 'Okumura': [3554, 3623, 3684], '7890-7897Crossref': [3564, 3633, 3694], '(129)': [3567, 3636, 3697], 'caspase-1/8': [3572], 'calpain': [3574], 'dispensable': [3576], 'release': [3579], 'macrophage': [3581], 'Murine': [3585], 'spontaneously,': [3589], 'secretion': [3592], 'increased': [3594], 'LPS': [3596], 'phorbol': [3598], '12-myristate': [3599], '13-acetate': [3600], 'plus': [3601], 'ionomycin': [3602], 'peritoneal': [3605, 3704], 'macrophages': [3606, 3705], 'caspase-1-deficient': [3608, 3707], 'BALB/c': [3609], 'mice': [3610], 'discrepancy': [3640], 'explained': [3646], 'fact': [3649], 'experiment': [3652], 'lines,': [3663], 'conflicting': [3666], 'mice.': [3708], 'significant': [3712], 'sequence': [3713], 'homology': [3714], 'between': [3715], 'IL-33,': [3719, 3966], 'they': [3720], 'share': [3721, 4239], '55%': [3723], 'identity': [3724], 'level.Splice': [3729], 'atypical': [3732], 'genes,': [3735], 'yet': [3736], 'exist': [3739], 'some': [3741], 'IL-15,': [3745, 3903, 3983], 'IL-1F7,': [3746], 'IL-32,': [3747], 'VEGF': [3749], '(49Kim': [3750], 'Han': [3752], 'Azam': [3754, 3776, 4476], 'D.Y.': [3757], 'Dinarello': [3758, 3784, 4480], '22:': [3762], '131-142Abstract': [3763], '(485)': [3771], '53Bufler': [3774], 'Gamboni-Robertson': [3778], 'Reznikov': [3780], 'L.L.': [3781], 'Kumar': [3782], 'Kim': [3786, 4482], '99:': [3794], '13723-13728Crossref': [3795], '(200)': [3798], '54Kumar': [3801], 'Hanning': [3803], 'C.R.': [3804], 'Brigham-Burke': [3805], 'Rieman': [3807], 'Lehr': [3809], 'Khandekar': [3811], 'Kirkpatrick': [3813], 'Scott': [3815], 'G.F.': [3816], 'Lee': [3817], 'Lynch': [3819], 'F.J.': [3820], 'Gao': [3821], 'Gambotto': [3823], 'Lotze': [3825], 'M.T.': [3826], '18:': [3829], '61-71Crossref': [3830], '(211)': [3833], '55Meazza': [3836], 'Verdiani': [3838], 'Biassoni': [3840], 'Coppolecchia': [3842], 'Gaggero': [3844], 'Orengo': [3846], 'A.M.': [3847], 'Colombo': [3848], 'M.P.': [3849], 'Azzarone': [3850], 'Ferrini': [3852], 'Oncogene.': [3854], '1996;': [3855, 4367], '12:': [3856], '2187-2192PubMed': [3857], '56Nishimura': [3860], 'Washizu': [3862], 'Nakamura': [3864], 'Enomoto': [3866], 'Yoshikai': [3868], '160:': [3873], '936-942PubMed': [3874], '57Pufe': [3877], 'Petersen': [3879], 'Tillmann': [3881], 'Mentlein': [3883], '2001;': [3887, 4462], '44:': [3888], '1082-1088Crossref': [3889], '(161)': [3892], 'There': [3895], 'two': [3897], 'isoforms': [3898, 4118], 'well': [3901], 'one': [3904, 3916], 'long': [3907, 4141], '(48': [3910], 'acids)': [3912, 3924], 'other': [3915, 4113], '(21': [3922], 'due': [3925], '5': [3932], '(58Tagaya': [3933, 4152], 'Kurys': [3935, 4154], 'Thies': [3937, 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