TAZ Interacts with TTF-1 and Regulates Expression of Surfactant Protein-C

Name: Work Video:
Duration: 3 min 30 s
Kwon-Sik Park; Jeffrey A. Whitsett; Tina Di Palma; Jeong‐Ho Hong; Michael B. Yaffe; Mariastella Zannini
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'https://openalex.org/W2165432409', 'https://openalex.org/W2166180405', 'https://openalex.org/W2203435726', 'https://openalex.org/W2315096416', 'https://openalex.org/W2329456180', 'https://openalex.org/W4255164449', 'https://openalex.org/W4302775339', 'https://openalex.org/W94709363'], 'related_works': ['https://openalex.org/W4397007845', 'https://openalex.org/W2913537206', 'https://openalex.org/W2275510245', 'https://openalex.org/W2207139036', 'https://openalex.org/W2162151490', 'https://openalex.org/W2115050780', 'https://openalex.org/W2066353226', 'https://openalex.org/W2019460535', 'https://openalex.org/W2014235532', 'https://openalex.org/W1981740764'], 'abstract_inverted_index': {'Thyroid': [0, 223, 446], 'transcription': [1, 20, 224, 243, 447, 456, 520, 1619, 1939, 2552, 2621], 'factor-1': [2, 225, 448], '(TTF-1/Nkx-2.1)': [3, 226], 'is': [4, 221, 227, 444, 511, 566, 657, 1133, 1180, 1607, 3767, 4472], 'required': [5, 228, 1305], 'for': [6, 29, 229, 252, 972, 1182, 1306, 2150, 2250, 2317, 2320, 2328, 2335, 2340, 2351, 2432, 2455, 2549, 2629, 2661, 3175, 3268, 3343, 3360, 3518, 3580, 3638, 3702, 3726, 4217], 'formation': [7, 230], 'of': [8, 13, 21, 66, 71, 79, 85, 90, 109, 119, 123, 131, 143, 150, 157, 187, 197, 207, 216, 231, 236, 244, 289, 294, 302, 308, 313, 332, 342, 346, 354, 366, 373, 380, 410, 420, 430, 439, 514, 518, 578, 649, 671, 810, 970, 980, 1000, 1177, 1203, 1248, 1309, 1318, 1364, 1477, 1510, 1588, 1617, 1626, 1876, 1927, 1957, 2044, 2069, 2089, 2107, 2113, 2124, 2245, 2325, 2348, 2445, 2516, 2564, 2600, 2602, 2731, 2764, 2778, 2799, 2811, 2885, 2896, 2903, 2917, 2928, 2940, 2944, 2955, 3039, 3043, 3201, 3236, 3247, 3257, 3263, 3299, 3471, 3611, 3624, 3717, 3735, 3760, 3771, 3811, 3910, 3912, 3982, 4001, 4018, 4027, 4035, 4122, 4142, 4145, 4149, 4166, 4176, 4205, 4212, 4222, 4248, 4254, 4404, 4422, 4437, 4449, 4455, 4465, 4470], 'the': [9, 25, 64, 69, 75, 77, 83, 88, 139, 144, 148, 155, 170, 184, 194, 200, 214, 232, 248, 287, 292, 298, 300, 306, 311, 362, 367, 371, 378, 393, 407, 417, 423, 437, 515, 570, 579, 647, 665, 732, 742, 804, 808, 978, 997, 1001, 1050, 1171, 1193, 1246, 1307, 1310, 1316, 1328, 1371, 1379, 1450, 1460, 1474, 1504, 1518, 1580, 1909, 1928, 1932, 2073, 2090, 2114, 2169, 2261, 2456, 2463, 2472, 2476, 2534, 2562, 2598, 2612, 2671, 2808, 2812, 2893, 2897, 2904, 2925, 2929, 2941, 2952, 2956, 2965, 3029, 3033, 3040, 3044, 3254, 3388, 3401, 3465, 3469, 3472, 3510, 3689, 3708, 3718, 3724, 3733, 3745, 3756, 3763, 3809, 3916, 3933, 3941, 3944, 3959, 3979, 3990, 4002, 4006, 4016, 4019, 4052, 4064, 4074, 4085, 4112, 4120, 4123, 4146, 4150, 4164, 4167, 4174, 4203, 4257, 4273, 4291, 4300, 4307, 4363, 4367, 4419, 4430, 4435, 4450, 4463], 'lung': [10, 30, 104, 233, 253, 327, 460, 652, 973, 985, 1184, 2690, 3095, 3766, 3917, 3934, 4054, 4081, 4473], 'and': [11, 46, 82, 116, 126, 133, 165, 204, 234, 269, 305, 339, 349, 356, 388, 427, 575, 651, 654, 669, 741, 815, 819, 821, 988, 1060, 1072, 1080, 1146, 1174, 1186, 1251, 1355, 1361, 1506, 1582, 1638, 1647, 1861, 1866, 1883, 1904, 1944, 2082, 2129, 2131, 2146, 2148, 2154, 2162, 2203, 2242, 2420, 2424, 2435, 2466, 2475, 2497, 2518, 2533, 2606, 2627, 2664, 2679, 2684, 2698, 2726, 2804, 2839, 2889, 2921, 2949, 2973, 2996, 3032, 3035, 3050, 3083, 3102, 3162, 3166, 3228, 3270, 3301, 3327, 3346, 3349, 3362, 3371, 3395, 3475, 3501, 3509, 3558, 3677, 3697, 3730, 3777, 3798, 3808, 3845, 3985, 4059, 4062, 4071, 4106, 4130, 4171, 4219, 4250, 4266, 4298, 4425], 'differentiation': [12, 235], 'peripheral': [14, 237, 1867, 3983], 'respiratory': [15, 91, 140, 238, 314, 363, 573, 672, 1061, 1078, 2120, 3750, 3960, 3980, 4065], 'epithelial': [16, 92, 105, 114, 117, 141, 239, 315, 328, 337, 340, 364, 673, 1142, 1325, 2087, 2121, 3096, 3751, 4066], 'cells.': [17, 240, 1326, 2122, 3631, 3752, 4412], 'TTF-1': [18, 132, 198, 217, 241, 355, 421, 440, 643, 734, 806, 971, 1064, 1132, 1178, 1188, 1313, 1332, 1343, 1365, 1456, 1478, 1511, 1589, 1611, 1629, 2048, 2070, 2081, 2097, 2108, 2918, 2945, 3101, 3361, 3731, 3844, 4107, 4131, 4177, 4218, 4267, 4471], 'activates': [19, 242, 807], 'target': [22, 219, 245, 442, 1204, 1319, 1337, 1595, 1627], 'genes,': [23, 246], 'including': [24, 247, 738, 1076], 'surfactant': [26, 134, 249, 357, 465, 811, 1249, 1311, 3103, 3736, 3846, 4152], 'proteins': [27, 250, 812, 1592, 3104, 3304, 3615, 3684, 3747, 3847], 'critical': [28, 251, 968, 1181], 'function.': [31, 254], 'A': [32, 255, 2403, 3602, 4079], 'recently': [33, 256, 1821], 'identified': [34, 257, 1244], 'protein': [35, 127, 135, 258, 350, 358, 466, 825, 1250, 1255, 1949, 2879, 3318, 3442, 3588, 3626, 4004], 'TAZ': [36, 67, 80, 86, 97, 124, 152, 171, 181, 189, 208, 259, 290, 303, 309, 320, 347, 375, 394, 404, 412, 431, 1814, 1871, 1885, 1914, 1919, 2060, 2093, 2271, 2446, 2603, 2732, 2765, 2801, 2886, 3300, 3303, 3345, 3385, 3710, 3729, 3761, 3800, 3812, 3821, 3913, 3927, 3954, 3973, 4003, 4010, 4028, 4047, 4105, 4118, 4126, 4129, 4162, 4183, 4201, 4249, 4255, 4265, 4276, 4281, 4348, 4406, 4416, 4438, 4466], '(transcriptional': [37, 260, 1815], 'co-activator': [38, 261, 1816, 1924], 'with': [39, 58, 129, 174, 262, 281, 352, 397, 1590, 1603, 1614, 1631, 1817, 1942, 2053, 2096, 2343, 2390, 2426, 2588, 2666, 2784, 3186, 3219, 3335, 3393, 3452, 3544, 3565, 3621, 3653, 3769, 3816, 4041, 4135, 4238, 4245, 4357], 'PDZ-binding': [40, 49, 263, 272, 1818, 1906, 4308], 'motif)': [41, 264, 1819], 'contains': [42, 265, 1344, 1886, 1894], 'a': [43, 47, 210, 266, 270, 433, 512, 660, 1352, 1356, 1455, 1470, 1599, 1615, 1824, 1887, 1890, 1895, 1900, 1905, 1922, 2050, 2067, 2257, 2344, 2443, 2619, 2703, 2776, 3199, 3566, 3645, 3654, 3962, 4136, 4158, 4186, 4195, 4287], 'WW': [44, 267, 1929, 2099], 'domain': [45, 186, 268, 409, 1367, 1373, 1383, 1445, 1462, 1930, 1948, 2100], 'COOH-terminal': [48, 271, 1357, 1507, 1583, 1891, 4303], 'motif': [50, 273, 1907, 1936, 2046, 2106], 'that': [51, 169, 180, 274, 392, 403, 565, 983, 1370, 1610, 1893, 1912, 2079, 3098, 3770, 4210, 4347], 'are': [52, 275, 1304, 2084, 2478, 2521, 2631, 3087, 3840, 4268], 'proposed': [53, 276], 'to': [54, 183, 191, 277, 406, 414, 1069, 1340, 1378, 1448, 1593, 1898, 1931, 2102, 2109, 2168, 2543, 2596, 2702, 3295, 3329, 3464, 3467, 3507, 3529, 3618, 3742, 3842, 3998, 4157, 4194, 4294, 4365], 'mediate': [55, 278, 1449, 1586], 'its': [56, 279, 655, 1466, 3347, 3363, 4235], 'interactions': [57, 280, 1587, 3727], 'various': [59, 282, 1073, 2333, 4456], 'transcriptional': [60, 195, 283, 418, 1334, 1467, 1923, 1955, 4351, 4420, 4447, 4468], 'proteins.': [61, 284, 4459], 'To': [62, 285, 3753, 4460], 'determine': [63, 286, 3754, 4116], 'role': [65, 84, 288, 307, 969], 'in': [68, 74, 87, 101, 138, 291, 297, 310, 324, 361, 569, 659, 664, 977, 996, 1049, 1055, 1130, 1135, 1200, 1245, 1323, 1384, 1458, 1472, 1517, 1598, 1880, 2047, 2058, 2065, 2086, 2119, 2159, 2179, 2256, 2385, 2523, 2546, 2550, 2561, 2579, 2657, 2728, 2788, 2807, 2892, 2924, 2951, 2964, 3138, 3172, 3181, 3206, 3479, 3692, 3713, 3732, 3749, 3762, 3774, 3830, 3915, 3921, 3932, 3943, 3958, 3968, 3978, 3989, 4005, 4015, 4029, 4051, 4063, 4073, 4178, 4227, 4270, 4290, 4410], 'regulation': [70, 89, 206, 293, 312, 429, 1176, 3734], 'gene': [72, 93, 295, 316, 1053, 1596, 2115, 3031, 3737, 4369], 'expression': [73, 81, 94, 156, 296, 304, 317, 379, 644, 656, 809, 1597, 1877, 2601, 3222, 3470, 3758, 3911, 3942, 4221], 'lung,': [76, 299, 805, 2059], 'sites': [78, 301, 2599, 2810, 2895, 2927, 2954, 4000, 4216], 'were': [95, 318, 1512, 1878, 2138, 2157, 2206, 2268, 2312, 2357, 2369, 2422, 2609, 2655, 2677, 2692, 2841, 2974, 3054, 3136, 3167, 3179, 3196, 3217, 3266, 3278, 3293, 3308, 3333, 3373, 3409, 3477, 3540, 3635, 3649, 3685, 3780, 4039, 4132, 4243, 4260, 4283, 4408], 'assessed.': [96, 319], 'mRNA': [98, 125, 321, 348, 2061, 3801, 3813, 3822, 3914, 3928, 3955, 3974], 'was': [99, 322, 975, 1446, 1463, 1479, 1820, 2062, 2165, 2177, 2191, 2240, 2248, 2388, 2439, 2528, 2537, 2555, 2586, 2733, 2773, 2794, 2880, 2906, 2912, 2935, 3250, 3322, 3391, 3443, 3462, 3505, 3513, 3526, 3563, 3589, 3596, 3605, 3740, 3783, 3802, 3823, 3918, 3929, 3946, 3956, 3965, 3975, 3986, 3996, 4012, 4048, 4345], 'detected': [100, 323, 2057, 2064, 3803, 3825, 3931, 3957, 3967, 3976, 3988, 4013, 4049], 'immortalized': [102, 325, 3093], 'mouse': [103, 110, 145, 158, 326, 333, 368, 381, 459, 1862, 2185, 2800, 3045, 3094, 3765, 3789, 3832, 4008, 4031, 4037, 4151, 4168], 'cells,': [106, 115, 329, 338, 4229, 4272], 'primary': [107, 330, 1451, 4086], 'isolates': [108, 331], 'alveolar': [111, 334, 474, 1136, 2186, 3833], 'type': [112, 335, 475, 1137, 2187, 3834], 'II': [113, 336, 1138, 2188, 3835], 'cells': [118, 142, 341, 365, 668, 674, 1139, 2088, 2156, 2189, 2205, 3086, 3097, 3135, 3178, 3195, 3408, 3450, 3476, 3836, 4067, 4180, 4242], 'fetal': [120, 343, 2091, 2136, 2413, 2689, 3188, 3790, 4020, 4030, 4036, 4053], 'lung.': [121, 146, 344, 369, 1884, 2092, 4009, 4032], 'Sites': [122, 345], 'overlapped': [128, 351], 'those': [130, 353], 'C': [136, 359, 816], '(SP-C)': [137, 360], 'In': [147, 370, 731, 803, 2072, 2381, 2581, 3438], 'presence': [149, 372, 2043], 'TTF-1,': [151, 192, 374, 415, 454, 3227, 3772, 4251], 'synergistically': [153, 376, 4172], 'activated': [154, 377, 1315, 4185], 'SP-C-luciferase': [159, 382], 'reporter': [160, 383, 3210, 4137, 4160, 4368], 'constructs.': [161, 384], 'Mammalian': [162, 385, 3365], 'two-hybrid': [163, 386], 'assays': [164, 387, 3405], 'pull-down': [166, 389, 3603], 'experiments': [167, 390, 2968], 'demonstrated': [168, 179, 391, 402], 'directly': [172, 395, 1314, 3691], 'interacted': [173, 396, 2095], 'TTF-1.': [175, 188, 398, 411, 4239], 'Further,': [176, 399], 'deletion': [177, 400, 2946], 'analysis': [178, 401, 3312], 'binds': [182, 190, 405, 413, 1189], 'NH2-terminal': [185, 408, 1349, 1366, 1372, 1444, 1461, 1505, 2104], 'increasing': [193, 416, 4246], 'activity': [196, 215, 419, 438, 1179, 1308, 1335, 1453, 1483, 3272, 4121, 4165, 4204, 4352, 4421, 4441, 4469], 'on': [199, 218, 422, 441, 1336, 1623, 1938, 2374, 2584, 3324, 3644, 3707, 3793, 4256, 4439, 4467], 'SP-C': [201, 424, 2083, 2117, 3046, 4114, 4124, 4169, 4188, 4258, 4451], 'promoter.': [202, 425], 'Developmental': [203, 426], 'cell-selective': [205, 428], 'provides': [209, 432, 2049], 'mechanism': [211, 434], 'by': [212, 435, 1330, 2194, 2260, 2371, 2441, 2796, 2882, 2908, 2914, 2937, 3252, 3280, 3310, 3607, 3687, 3920, 4275, 4353], 'which': [213, 436, 1131, 1331, 1459, 1473, 3839], 'genes': [220, 443, 737, 1205, 1256, 1320], 'modulated.': [222, 445], '(TTF-1,': [449], '1The': [450], 'abbreviations': [451], 'used': [452, 2249, 2267, 2616, 2774, 2963, 3997], 'are:': [453], 'thyroid': [455, 650, 666], 'factor-1;': [457], 'MLE,': [458], 'epithelial;': [461], 'SP-A,': [462], 'SP-B,': [463, 818], 'SP-C,': [464], 'A,': [467, 813], 'B,': [468, 814], 'C;': [469], 'NFI,': [470], 'nuclear': [471, 1641, 1917], 'factor-I;': [472], 'AEII,': [473], 'II;': [476], 'RT,': [477], 'reverse': [478], 'transcription;': [479], 'CAT,': [480], 'chloramphenicol': [481, 4223], 'acetyltransferase;': [482], 'GST,': [483], 'glutathione': [484], 'S-transferase;': [485], 'GFP,': [486], 'green': [487], 'fluorescent': [488], 'protein;': [489, 497, 501, 504], 'EGFP,': [490], 'enhanced': [491, 4173, 4202], 'GFP;': [492], 'luc,': [493], 'luciferase;': [494], 'CBP,': [495], 'CREB-binding': [496], 'CREB,': [498], 'cAMP-response': [499], 'element-binding': [500], 'C/EBP,': [502], 'CCAAT/enhancer-binding': [503], 'E,': [505], 'embryonic': [506, 2416], 'day.': [507], 'also': [508, 993, 3824, 3966, 4184], 'termed': [509, 1192], 'T-EBP/Nkx2.1)': [510], 'member': [513], 'Nkx-2': [516], 'class': [517], 'homeodomain-containing': [519], 'factors': [521], '(1Civitareale': [522, 745], 'D.': [523, 583, 746, 936, 1093, 1099, 1209, 1213, 1419, 1764, 1832, 1965, 2003, 2849, 4316, 4375], 'Lonigro': [524, 747], 'R.': [525, 530, 554, 591, 748, 753, 791, 855, 938, 1114, 1226, 1260, 1285, 1397, 1428, 1532, 1553, 1560, 1653, 1660, 1834, 1967, 2851, 2981, 3009, 4318, 4377], 'Sinclair': [526, 749], 'A.J.': [527, 750], 'Di': [528, 552, 589, 751, 789, 1224, 1283, 1395, 1530, 1558, 1658, 3007], 'Lauro': [529, 553, 590, 752, 790, 1225, 1284, 1396, 1531, 1559, 1659, 3008], 'EMBO': [531, 555, 754, 1849, 1982, 2866, 4333, 4392], 'J.': [532, 556, 701, 720, 755, 836, 875, 899, 951, 1117, 1286, 1398, 1434, 1493, 1533, 1563, 1663, 1687, 1715, 1736, 1739, 1785, 1801, 1850, 1983, 2005, 2010, 2032, 2229, 2747, 2825, 2867, 3010, 3065, 3422, 3854, 3873, 3892, 4334, 4393], '1989;': [533, 756, 2828], '8:': [534, 757], '2537-2542Crossref': [535, 758], 'PubMed': [536, 560, 596, 618, 638, 690, 707, 726, 759, 798, 847, 864, 886, 910, 927, 962, 1022, 1042, 1123, 1164, 1233, 1269, 1297, 1409, 1438, 1497, 1544, 1574, 1674, 1698, 1726, 1750, 1771, 1809, 1854, 1987, 2021, 2037, 2234, 2649, 2721, 2753, 2834, 2871, 2990, 3021, 3076, 3129, 3433, 3860, 3879, 3903, 4338, 4397], 'Scopus': [537, 561, 619, 639, 691, 708, 727, 760, 799, 848, 865, 887, 911, 928, 963, 1023, 1043, 1124, 1165, 1234, 1270, 1298, 1410, 1439, 1498, 1545, 1575, 1675, 1699, 1727, 1751, 1772, 1810, 1855, 1988, 2022, 2038, 2235, 2650, 2722, 2754, 2872, 2991, 3022, 3077, 3130, 3434, 3861, 3880, 3904, 4339, 4398], '(326)': [538, 761], 'Google': [539, 563, 597, 621, 641, 693, 710, 729, 762, 781, 801, 850, 867, 889, 913, 930, 965, 1025, 1045, 1126, 1167, 1236, 1272, 1300, 1412, 1441, 1500, 1547, 1577, 1677, 1701, 1729, 1753, 1774, 1790, 1812, 1857, 1990, 1998, 2024, 2040, 2237, 2652, 2724, 2756, 2835, 2874, 2993, 3024, 3079, 3132, 3436, 3863, 3882, 3906, 4341, 4400], 'Scholar,': [540, 598, 622, 694, 711, 763, 782, 851, 868, 890, 914, 931, 1026, 1273, 1413, 1548, 1678, 1702, 1730, 1754, 1775, 1791, 1991, 1999, 2025, 3864, 3883], '2Guazzi': [541], 'S.': [542, 600, 632, 1004, 1036, 1103, 1156, 1215, 1219, 1223, 1430, 2713, 2816, 3124], 'Price': [543, 584, 785], 'M.': [544, 547, 585, 588, 676, 678, 767, 769, 771, 786, 788, 934, 1105, 1217, 1276, 1280, 1388, 1392, 1426, 1485, 1523, 1527, 1562, 1662, 1708, 1710, 1738, 1838, 1971, 1993, 2030, 2223, 2855, 3000, 3004, 3417, 4322, 4381], 'De': [545, 1424], 'Felice': [546, 587, 933, 1275, 1387, 1425, 1522, 2999], 'Damante': [548, 1277, 1389, 1431, 1524, 3001], 'G.': [549, 626, 682, 1030, 1207, 1278, 1390, 1415, 1432, 1525, 1758, 3002], 'Mattei': [550], 'M.G.': [551], '1990;': [557], '9:': [558, 1996], '3631-3639Crossref': [559], '(472)': [562], 'Scholar)': [564, 2725], 'selectively': [567], 'expressed': [568, 1322, 4269], 'developing': [571, 580, 3764, 4007], 'thyroid,': [572, 733, 987, 1059, 2066], 'epithelium,': [574, 3961], 'restricted': [576], 'areas': [577], 'brain': [581], '(3Lazzaro': [582], 'de': [586], 'Development.': [592], '1991;': [593, 2034], '113:': [594], '1093-1104Crossref': [595], '4Kimura': [599], 'Hara': [601, 1005], 'Y.': [602, 940, 1006, 1844, 1977, 2861, 4328, 4387], 'Pineau': [603, 1007], 'T.': [604, 765, 775, 1008, 1551, 1651, 1842, 1975, 2859, 4326, 4385], 'Fernandez-Salguero': [605, 1009], 'P.': [606, 624, 630, 1010, 1028, 1034, 2007], 'Fox': [607, 1011], 'C.H.': [608, 1012], 'Ward': [609, 1013], 'J.M.': [610, 1014, 1712, 2225], 'Gonzalez': [611, 1015], 'F.J.': [612, 1016], 'Genes': [613, 1017], 'Dev.': [614, 633, 1018, 1037, 1159, 2644, 2716], '1996;': [615, 704, 723, 902, 1019, 2750, 3068, 3857, 3876], '10:': [616, 1020], '60-69Crossref': [617, 1021], '(1013)': [620, 1024], '5Minoo': [623, 1027], 'Su': [625, 1029], 'Drum': [627, 1031], 'H.': [628, 784, 1032, 1084, 1088, 1095, 1097, 1282, 1394, 1529, 1684, 2820, 2822, 3006, 3889], 'Bringas': [629, 1033], 'Kimura': [631, 1035, 1155, 2712], 'Biol.': [634, 794, 837, 860, 876, 900, 952, 1038, 1160, 1265, 1287, 1399, 1534, 1564, 1664, 1688, 1716, 1740, 1767, 1805, 2011, 2645, 2717, 2826, 2986, 3011, 3066, 3423, 3893], '1999;': [635, 1039, 1787], '209:': [636, 1040], '60-71Crossref': [637, 1041], '(367)': [640, 1044], 'Scholar).': [642, 730, 802, 966, 1046, 1127, 1168, 1237, 1301, 1442, 1501, 1578, 1813, 1858, 2041, 2238, 2411, 2653, 2757, 2836, 2875, 3025, 3080, 3133, 3437, 3907, 4342, 4401], 'begins': [645], 'at': [646, 1908, 2140, 2332, 2415, 2462, 2471, 2558, 2694, 2775, 3169, 3198, 3400, 3515, 3521, 3583, 3591, 3641, 3699, 3804, 3826, 3936, 3949, 4056, 4068], 'onset': [648], 'formation,': [653], 'maintained': [658], 'highly': [661], 'regulated': [662], 'pattern': [663, 3759, 3909], 'follicular': [667], 'subsets': [670], '(6Boshart': [675], 'Klüppel': [677], 'Schmidt': [679], 'A.': [680, 1091, 1101, 1108, 1116, 1555, 1655, 1706, 1734, 1840, 1973, 2027, 2857, 3125, 3415, 4324, 4383], 'Schütz': [681], 'Luckow': [683], 'B.': [684, 1086, 1797], 'Gene': [685], '(Amst.).': [686], '1992;': [687, 795], '110:': [688], '129-130Crossref': [689], '(230)': [692], '7Stahlman': [695], 'M.T.': [696, 2001, 3849], 'Gray': [697, 3850], 'M.E.': [698, 3851], 'Whitsett': [699, 718, 832, 856, 873, 917, 949, 1157, 1261, 1488, 1685, 1782, 2642, 2714, 2745, 2982, 3117, 3418, 3852, 3871, 3890], 'J.A.': [700, 719, 833, 857, 874, 918, 950, 1158, 1262, 1489, 1686, 1783, 2643, 2715, 2746, 2983, 3118, 3419, 3853, 3872, 3891], 'Histochem.': [702, 721, 2748, 3855, 3874], 'Cytochem.': [703, 722, 2749, 3856, 3875], '44:': [705, 724, 2751, 3858, 3877], '673-678Crossref': [706, 3859], '(194)': [709, 3862], '8Zhou': [712, 3865], 'L.': [713, 715, 916, 1211, 1417, 1421, 1557, 1657, 2740, 2742, 3866, 3868], 'Lim': [714, 2741, 3867], 'Costa': [716, 2743, 3869], 'R.H.': [717, 2744, 3870], '1183-1193Crossref': [725, 2752, 3878], '(248)': [728, 2755, 3881], 'regulates': [735, 1333], 'thyroid-specific': [736], 'thyroglobulin,': [739], 'thyroperoxidase,': [740], 'sodium-iodide': [743], 'symporter': [744], '9Endo': [764], 'Kaneshige': [766], 'Nakazato': [768], 'Ohmori': [770], 'Harii': [772], 'N.': [773], 'Onaya': [774], 'Mol.': [776, 792, 858, 1263, 1765, 1804, 2984], 'Endocrinol.': [777], '1997;': [778, 924, 1494], '11:': [779], '1747-1755PubMed': [780], '10Francis-Lang': [783], 'Polycarpou-Schwarz': [787], 'Cell.': [793, 859, 1264, 1766, 2985], '12:': [796], '576-588Crossref': [797], '(210)': [800], '(SP-A,': [817], 'SP-C)': [820], 'Clara': [822, 1252], 'cell': [823, 1143, 1253, 3315, 3320, 3511], 'secretory': [824, 1254], '(11Bruno': [826], 'M.D.': [827], 'Bohinski': [828], 'R.J.': [829, 853, 1258, 2979], 'Huelsman': [830], 'K.M.': [831], 'Korfhagen': [834, 2640], 'T.R.': [835, 2641], 'Chem.': [838, 877, 901, 953, 1288, 1400, 1535, 1565, 1665, 1689, 1717, 1741, 2012, 2827, 3012, 3067, 3424, 3894], '1995;': [839, 878, 1289, 1401, 1536, 3013], '270:': [840, 879, 1290, 1402, 1537, 3014], '6531-6536Abstract': [841], 'Full': [842, 844, 881, 883, 905, 907, 957, 959, 1292, 1294, 1404, 1406, 1539, 1541, 1569, 1571, 1669, 1671, 1693, 1695, 1721, 1723, 1745, 1747, 2016, 2018, 2831, 3016, 3018, 3071, 3073, 3428, 3430, 3898, 3900], 'Text': [843, 845, 882, 884, 906, 908, 958, 960, 1293, 1295, 1405, 1407, 1540, 1542, 1570, 1572, 1670, 1672, 1694, 1696, 1722, 1724, 1746, 1748, 2017, 2019, 2832, 3017, 3019, 3072, 3074, 3429, 3431, 3899, 3901], 'PDF': [846, 885, 909, 961, 1296, 1408, 1543, 1573, 1673, 1697, 1725, 1749, 2020, 2833, 3020, 3075, 3432, 3902], '(240)': [849], '12Bohinski': [852], 'DiLauro': [854, 937, 1113, 1259, 2980], '1994;': [861, 1230, 1266, 1995, 2987], '14:': [862, 1267, 2988], '5671-5681Crossref': [863, 1268, 2989], '(486)': [866, 1271, 2992], '13Yan': [869], 'C.': [870, 1423, 1491, 1680, 1704, 1732, 1781, 3421, 3885], 'Sever': [871], 'Z.': [872, 1777], '24852-24857Abstract': [880], '(114)': [888], '14Kelly': [891], 'S.E.': [892, 942, 1150, 2637, 2707, 3058], 'Bachurski': [893, 945, 1778, 3059, 3113], 'C.J.': [894, 946, 1756, 1779, 3060, 3114], 'Burhans': [895, 3061], 'M.S.': [896, 3062], 'Glasser': [897, 1681, 2638, 3063, 3886], 'S.W.': [898, 1682, 2639, 3064, 3887], '271:': [903, 3069], '6881-6888Abstract': [904, 3070], '(218)': [912, 3078], '15Zhang': [915], 'Stripp': [919], 'B.R.': [920], 'Biochim.': [921], 'Biophys.': [922], 'Acta.': [923], '1350:': [925], '359-367Crossref': [926], '(127)': [929], '16de': [932], 'Silberschmidt': [935], 'Xu': [939, 2004], 'Wert': [941], 'Weaver': [943, 2197, 2226], 'T.E.': [944, 2227], 'Clark': [947, 3111], 'J.C.': [948, 1799, 3112], '2003;': [954, 1566, 1666, 1768], '278:': [955, 1567, 1667], '35574-35583Abstract': [956], '(136)': [964], 'The': [967, 1443, 1873, 2042, 2173, 2264, 2309, 2354, 2366, 2430, 2452, 2525, 2876, 2900, 2961, 3209, 3244, 3524, 3586, 3632, 3682, 3908, 4413], 'morphogenesis': [974, 1185], 'shown': [976, 1447, 2078, 4346], 'study': [979], 'TTF-1-null': [981], 'mice': [982, 992, 1129, 2137, 2212], 'lacked': [984], 'parenchyma,': [986], 'pituitary': [989], 'glands.': [990], 'TTF-null': [991], 'have': [994, 1242, 1368, 2077, 2458, 2969], 'defects': [995], 'ventral': [998], 'area': [999], 'forebrain': [1002], '(4Kimura': [1003], 'Clinically,': [1047], 'mutations': [1048], 'human': [1051, 1860], 'Ttf-1': [1052], 'result': [1054], 'central': [1056, 1888], 'nervous': [1057], 'system,': [1058], 'disorders.': [1062], 'Human': [1063], 'haploinsufficiency': [1065], 'has': [1066, 1374], 'been': [1067, 1243, 2970], 'linked': [1068, 4156], 'choreoathetosis,': [1070], 'hypothyroidism,': [1071], 'pulmonary': [1074, 1081, 1147, 3969], 'disorders': [1075], 'neonatal': [1077], 'distress': [1079], 'infections': [1082], '(17Krude': [1083], 'Schutz': [1085], 'Biebermann': [1087], 'von': [1089, 1106], 'Moers': [1090], 'Schnabel': [1092], 'Neitzel': [1094], 'Tonnies': [1096], 'Weise': [1098], 'Lafferty': [1100], 'Schwarz': [1102], 'DeFelice': [1104], 'Deimling': [1107], 'van': [1109], 'L': [1110], 'eghem': [1111], 'F.': [1112, 1221, 1828, 1961, 2845, 4312, 4371], 'Gruters': [1115], 'Clin.': [1118], 'Invest.': [1119], '2002;': [1120, 1161, 1690, 1718, 2231, 2718, 3895], '109:': [1121], '475-480Crossref': [1122], '(297)': [1125], 'Transgenic': [1128], 'overexpressed': [1134], 'caused': [1140], 'dose-dependent': [1141, 4261], 'hyperplasia,': [1144], 'emphysema,': [1145], 'inflammation': [1148], '(18Wert': [1149, 2706], 'Dey': [1151, 2708], 'C.R.': [1152, 2709], 'Blair': [1153, 2710], 'P.A.': [1154, 1830, 1963, 2711, 2847, 4314, 4373], '242:': [1162, 2719], '75-87Crossref': [1163, 2720], '(78)': [1166, 2723], 'Taken': [1169, 4444], 'together,': [1170, 4445], 'temporal,': [1172], 'spatial,': [1173], 'quantitative': [1175], 'normal': [1183], 'physiology.': [1187], 'an': [1190, 1348, 1945, 2103, 4206], 'element': [1191], 'NKX': [1194, 1239], 'binding': [1195, 1240, 1926, 1958, 2101, 3633, 4215, 4454], 'element(s),': [1196], 'containing': [1197, 2378, 3028, 3143, 3546, 3568, 3656], '5′-TNAAGTG-3′,': [1198], 'found': [1199], 'regulatory': [1201, 1624], 'regions': [1202, 1625], '(19Damante': [1206], 'Fabbro': [1208, 1418], 'Pellizzari': [1210, 1420], 'Civitareale': [1212], 'Guazzi': [1214], 'Polycarpou-Schwartz': [1216], 'Cauci': [1218], 'Quadrifoglio': [1220], 'Formisano': [1222, 1429], 'Nucleic': [1227], 'Acids': [1228], 'Res.': [1229], '22:': [1231], '3075-3083Crossref': [1232], '(104)': [1235, 1299, 1411, 1546, 3023], 'Multiple': [1238], 'element(s)': [1241], 'promoters': [1247, 1317, 1338, 2520, 4259], '(12Bohinski': [1257, 2978], '20De': [1274], 'Zannini': [1279, 1391, 1526, 1561, 1661, 3003], 'Francis-Lang': [1281, 1393, 1528, 3005], '26649-26656Abstract': [1291, 1403, 1538, 3015], 'These': [1302], 'elements': [1303], 'promoters.': [1312], 'when': [1321, 1515], 'non-respiratory': [1324], 'However,': [1327], 'mechanisms': [1329], 'remain': [1339], 'be': [1341], 'defined.': [1342], 'three': [1345, 3542], 'distinct': [1346, 3948], 'domains:': [1347], 'transactivation': [1350, 1452, 3192], 'domain,': [1351, 1903], 'DNA-binding': [1353], 'homeodomain,': [1354], 'activation': [1358, 1382, 1508, 2112, 4274], 'domain.': [1359], 'Structural': [1360], 'functional': [1362, 1375], 'studies': [1363, 3779], 'suggested': [1369], 'properties': [1376], 'similar': [1377], 'typical': [1380], 'acidic': [1381], 'VP16': [1385], '(20De': [1386, 1521, 2998], '21Tell': [1414], 'Perrone': [1416], 'Pucillo': [1422], 'Acquaviva': [1427], 'Biochem.': [1433, 1492], '1998;': [1435], '329:': [1436], '395-403Crossref': [1437], '(32)': [1440], 'because': [1454], 'mutant': [1457, 1471, 2947, 3302, 4417], 'deleted': [1464, 1480], 'lost': [1465, 4362], 'activity,': [1468], 'whereas': [1469, 4360, 4429], 'COOH': [1475, 1910], 'terminus': [1476, 1911], 'partially': [1481], 'reduced': [1482], '(22Ghaffari': [1484], 'Zeng': [1486], 'X.': [1487], 'Yan': [1490, 1780, 3420], '328:': [1495], '757-761Crossref': [1496], '(46)': [1499, 1752], 'Differences': [1502], 'between': [1503, 3728], 'domains': [1509, 1584], 'not': [1513, 2063, 3939, 3987, 4072], 'observed': [1514, 1879], 'tested': [1516], 'thyroglobulin': [1519], 'promoter': [1520, 2460, 2470, 2532, 2541, 3047, 4170, 4189, 4209, 4452], '23Di': [1549], 'Palma': [1550, 1650], 'Nitsch': [1552, 1556, 1652, 1656], 'Mascia': [1554, 1654], '3395-3402Abstract': [1568, 1668], '(124)': [1576, 1676], 'Thus,': [1579], 'NH2-': [1581], 'may': [1585, 1950, 4277], 'other': [1591, 1618], 'regulate': [1594, 1952, 2110], 'gene-specific': [1600], 'manner.': [1601], 'Consistent': [1602], 'this': [1604], 'concept,': [1605], 'it': [1606, 3739, 4344], 'increasingly': [1608], 'clear': [1609], 'functions': [1612, 1920], 'cooperatively': [1613], 'number': [1616, 2450], 'factors,': [1620], 'forming': [1621], 'complexes': [1622], 'genes.': [1628], 'interacts': [1630], 'Pax8,': [1632], 'GATA6,': [1633], 'STAT3,': [1634], 'retinoic': [1635], 'acid': [1636, 1935], 'receptor': [1637], 'associated': [1639], 'cofactors,': [1640], 'factor-I': [1642], '(NFI-B),': [1643], 'AP1': [1644], 'family': [1645], 'members,': [1646], 'BR22': [1648], '(23Di': [1649], '24Liu': [1679, 3884], 'Wan': [1683, 3888], '277:': [1691, 1719, 1788, 3896], '4519-4525Abstract': [1692, 3897], '(110)': [1700, 3905], '25Yan': [1703], 'Naltner': [1705, 1709, 1733], 'Martin': [1707], 'Fangman': [1711], 'Gurel': [1713], 'O.': [1714], '10967-10972Abstract': [1720], '(54)': [1728], '26Yan': [1731], 'Conkright': [1735, 2218], 'Ghaffari': [1737, 3416], '2001;': [1742, 1806], '276:': [1743], '21686-21691Abstract': [1744], '27Bachurski': [1755], 'Yang': [1757, 1794], 'Currier': [1759], 'T.A.': [1760], 'Gronstajski': [1761], 'R.M.': [1762], 'Hong': [1763], '23:': [1769], '9014-9024Crossref': [1770], '(55)': [1773], '28Sever-Chroneos': [1776], 'Am.': [1784, 1800, 2228], 'Physiol.': [1786, 2230], 'L79-L88PubMed': [1789], '29Yang': [1792], 'Y.S.': [1793], 'M.C.': [1795], 'Wang': [1796], 'Weissler': [1798], 'Respir.': [1802], 'Cell': [1803, 3081], '24:': [1807], '30-37Crossref': [1808], '(27)': [1811], 'discovered': [1822], 'as': [1823, 1921, 2213, 2269, 2313, 2358, 2396, 2479, 2615, 2633, 2736, 2975, 3411, 4355], '14-3-3-binding': [1825, 4292], 'molecule': [1826], '(30Kanai': [1827, 1960, 2844, 4311, 4370], 'Marignani': [1829, 1962, 2846, 4313, 4372], 'Sarbassova': [1831, 1964, 2002, 2848, 4315, 4374], 'Yagi': [1833, 1966, 2850, 4317, 4376], 'Hall': [1835, 1968, 2852, 4319, 4378], 'R.A.': [1836, 1969, 2853, 4320, 4379], 'Donowitz': [1837, 1970, 2854, 4321, 4380], 'Hisaminato': [1839, 1972, 2856, 4323, 4382], 'Fujiwara': [1841, 1974, 2858, 4325, 4384], 'Ito': [1843, 1976, 2860, 4327, 4386], 'Cantley': [1845, 1978, 2862, 4329, 4388], 'L.C.': [1846, 1979, 2863, 4330, 4389], 'Yaffe': [1847, 1980, 2008, 2864, 4331, 4390], 'M.B.': [1848, 1981, 2009, 2865, 4332, 4391], '2000;': [1851, 1984, 2013, 2868, 3425, 4335, 4394], '19:': [1852, 1985, 2869, 4336, 4395], '6778-6791Crossref': [1853, 1986, 2870, 4337, 4396], '(582)': [1856, 1989, 2873, 4340, 4399], 'Most': [1859], 'tissues,': [1863], 'except': [1864], 'thymus': [1865], 'blood': [1868], 'leukocytes,': [1869], 'express': [1870, 3099, 3843], 'mRNA.': [1872, 2604], 'highest': [1874], 'levels': [1875, 3829], 'kidney,': [1881], 'heart,': [1882], 'WW,': [1889], 'sequence': [1892, 2461], 'region': [1896, 2803, 2888, 2920, 2943, 3042, 4148], 'predicted': [1897], 'form': [1899], 'two-stranded': [1901], 'coiled-coil': [1902], 'localizes': [1913], 'into': [1915, 3397], 'discrete': [1916], 'foci.': [1918], 'through': [1925, 2098], '(L/P)PXY': [1933, 2045], 'amino': [1934, 2762], 'present': [1937, 2074], 'factors.': [1940], 'Interactions': [1941], '14-3-3': [1943], 'unknown': [1946], 'PDZ': [1947, 4457], 'therefore': [1951], 'trafficking': [1953], 'or': [1954, 3214, 3233, 3613, 4128], 'activities': [1956], 'partners': [1959], '31Sudol': [1992], 'Oncogene.': [1994], '2145-2152PubMed': [1997], '32Bedford': [2000], 'Leder': [2006], '275:': [2014, 3426], '10359-10369Abstract': [2015], '(66)': [2023], '33Lupas': [2026], 'Van': [2028], 'Dyke': [2029], 'Stock': [2031], 'Science.': [2033], '252:': [2035], '1162-1164Crossref': [2036], '(3482)': [2039], 'potential': [2051, 3725, 4236], 'interaction': [2052, 4237], 'TAZ.': [2054, 4046], 'Although': [2055, 3926, 3953], 'readily': [2056], 'site': [2068, 4293], 'activity.': [2071, 3297], 'study,': [2075], 'we': [2076], 'TAZ,': [2080, 2360], 'co-expressed': [2085], 'physically': [2094], 'LPPY': [2105], 'TTF-1-mediated': [2111], 'encoding': [2116, 3224, 3387], '(sftp-c)': [2118], 'Isolation': [2123], 'RNA': [2125, 2151, 2164, 2175, 2182, 2239, 2393, 2437, 3787], 'from': [2126, 2135, 2183, 2208, 2611, 3319, 3376, 3445, 3598, 3629, 3788, 3924, 4111], 'Mouse': [2127, 2412, 4113], 'Embryos': [2128], 'Cells,': [2130], 'Reverse': [2132], 'Transcription': [2133, 4110], '(RT)-PCR—Lungs': [2134], 'obtained': [2139, 2693, 3792], 'E11.5,': [2141, 3794], '12.5,': [2142, 2419], '13.5,': [2143, 3795], '15.5,': [2144, 3796], '16.5,': [2145, 3797], '17.0': [2147], 'lysed': [2149, 2158], 'preparation.': [2152], 'MLE-15': [2153, 3134, 3407, 4179, 4241, 4271, 4411], 'HeLa': [2155, 3177, 3194, 3314, 3630, 4228], 'Trizol': [2160], 'reagent,': [2161], 'total': [2163, 3245, 3625, 3786], 'extracted': [2166], 'according': [2167, 2542, 2701], "manufacturer's": [2170, 2672], 'specifications': [2171], '(Invitrogen).': [2172, 2263], 'final': [2174, 2345], 'pellet': [2176], 'dissolved': [2178], 'diethylpyrocarbonate-treated': [2180], 'water.': [2181], 'purified': [2184, 3444, 3831], '(AEII)': [2190], 'kindly': [2192], 'provided': [2193, 2255, 2259, 2545], 'Dr.': [2195, 3377], 'Timothy': [2196], '(Cincinnati': [2198, 3380], "Children's": [2199, 3381], 'Hospital,': [2200, 3382], 'Cincinnati,': [2201, 3383], 'OH),': [2202], 'AEII': [2204], 'prepared': [2207, 3628], '6-week-old': [2209], 'female': [2210], 'C57B/6': [2211], 'described': [2214, 2397, 2634, 2737, 2971, 3412], 'previously': [2215, 2398, 2635, 2738, 2843, 2972, 3056, 3413, 3617], '(34Rice': [2216], 'W.R.': [2217, 3110], 'J.J.': [2219], 'Na': [2220], 'C-L.': [2221], 'Ikegami': [2222], 'Shannon': [2224], '283:': [2232], 'L256-L264Crossref': [2233], '(142)': [2236], 'reverse-transcribed,': [2241], '1/20': [2243], 'volume': [2244], 'reverse-transcribed': [2246], 'product': [2247], 'subsequent': [2251, 2805, 2890, 2922], 'PCR': [2252, 2265, 2310, 2367, 2457, 2797, 2883, 2915, 2938], 'using': [2253, 2530, 2539, 2618, 3238, 3313, 3406, 3532, 3785], 'procedures': [2254, 2544], 'kit': [2258, 2548, 2622], 'manufacturer': [2262], 'primers': [2266, 2454], 'follows:': [2270, 2314, 2359, 2480, 2976], '5′': [2272, 2292, 2453, 2464, 2481, 4147], 'primer,': [2273, 2282, 2293, 2301, 2482, 2499], '5′-CGT': [2274], 'CCA': [2275, 2278], 'TCA': [2276, 2486, 2503, 2509], 'CTT': [2277], 'CCT': [2279, 2295], 'CG-3′;': [2280], '3′': [2281, 2467, 2473, 2498], '5′-ACT': [2283], 'GTA': [2284, 2296], 'GCA': [2285], 'CCC': [2286, 2288, 2485], 'TAA': [2287, 2484], 'CAG': [2289, 2493], 'G-3′;': [2290], 'β-actin': [2291], '5′-GTC': [2294], 'TGC': [2297, 2305], 'CTC': [2298], 'TGG': [2299], 'TC-3′;3′': [2300], '5′-TCG': [2302], 'TAC': [2303, 2501], 'TCC': [2304], 'TTG': [2306], 'CTG': [2307], 'AT-3′.': [2308], 'conditions': [2311], '95': [2315, 2326, 3700], '°C': [2316, 2327, 2339, 2350, 2560, 3643, 3701], '5': [2318, 3147, 3555, 3559], 'min': [2319, 3520, 3582, 3640, 3704], '1': [2321, 2329, 3158, 3487, 3493, 3670, 3673], 'cycle,': [2322], '30': [2323, 2336], 'cycles': [2324], 'min,': [2330], 'annealing': [2331, 2355], 'temperatures': [2334, 2356], 's,': [2337, 2342], '72': [2338, 2349], '30–40': [2341], 'extension': [2346], 'cycle': [2347], '7': [2352], 'min.': [2353], '58': [2361], '°C;': [2362], 'β-actin,': [2363], '60': [2364], '°C.': [2365, 3523, 3585, 3593], 'products': [2368], 'resolved': [2370, 3323], 'gel': [2372], 'electrophoresis': [2373], '1%': [2375, 2569], 'agarose': [2376], 'gels': [2377], 'ethidium': [2379], 'bromide.': [2380], 'Situ': [2382, 2401], 'Hybridization—Whole': [2383], 'mount': [2384], 'situ': [2386, 2582, 3775, 3922], 'hybridization': [2387, 2583, 2630, 3923], 'performed': [2389, 2556, 2587, 2734, 3410, 3606], 'digoxigenin-labeled': [2391], 'antisense': [2392, 2434, 2526, 2607], 'probes': [2394, 2438], 'essentially': [2395, 2632, 2735], '(35Wilkinson': [2399], 'D.G.': [2400], 'Hybridization:': [2402], 'Practical': [2404], 'Approach.': [2405], 'IRL': [2406], 'Press,': [2407], 'New': [2408], 'York1992:': [2409], '75-83Google': [2410], 'lungs': [2414, 3791, 3984, 4021, 4038], 'days': [2417], '11.5,': [2418], '13.5': [2421], 'dissected': [2423], 'fixed': [2425, 3251], '4%': [2427, 2785], 'paraformaldehyde/phosphate-buffered': [2428], 'saline.': [2429], 'template': [2431, 2614], 'making': [2433], 'sense': [2436, 2535], 'generated': [2440, 2610, 2795, 2881, 2913, 2936, 4284], 'amplifying': [2442], 'part': [2444], 'cDNA': [2447, 3386], '(GenBank™': [2448], 'accession': [2449], 'AJ299430).': [2451], 'T3': [2459, 2517, 2540], 'end': [2465], 'primer': [2468], 'T7': [2469, 2519, 2531], 'end,': [2474], 'sequences': [2477, 2515], '5′-AAT': [2483], 'CTA': [2487, 2504], 'AAG': [2488, 2511], 'GG': [2489, 2506], 'CAC': [2490, 2492], 'CAA': [2491, 2494], 'GTC': [2495], 'GTG-3′,': [2496], '5′-TAA': [2500], 'GAC': [2502], 'TAG': [2505], 'AGG': [2507], 'AAA': [2508], 'GGG': [2510], 'CGG': [2512], 'G-3′.': [2513], '(The': [2514], 'written': [2522], 'bold.)': [2524], 'probe': [2527, 2536], 'transcribed': [2529, 2538], 'Mega': [2547], 'vitro': [2551], '(Ambion).': [2553], 'Hybridization': [2554], 'overnight': [2557], '70': [2559], 'solution': [2563], '50%': [2565], 'formamide,': [2566], '5×': [2567], 'SSC,': [2568], 'SDS,': [2570], '50': [2571, 2575, 3572, 3577, 3657], 'μg/ml': [2572, 2576, 3148, 3151], 'yeast': [2573], 'tRNA,': [2574], 'heparin': [2577], 'sodium': [2578, 3156], 'diethylpyrocarbonate-H2O.': [2580], 'sections': [2585, 2676, 2783, 4034], '35S-nucleotide': [2589], 'labeled': [2590], '(1,000': [2591], 'Ci/nmol,': [2592], 'Amersham': [2593], 'Biosciences)': [2594], 'riboprobes': [2595, 2608], 'assess': [2597], 'Sense': [2605], 'same': [2613], 'above': [2617], 'Riboprobe': [2620], '(Promega,': [2623, 3273], 'Madison,': [2624, 3274], 'WI).': [2625, 3275], 'Conditions': [2626], 'solutions': [2628], '(36Wert': [2636], '1993;': [2646, 3126], '156:': [2647], '426-443Crossref': [2648], '(275)': [2651], 'Slides': [2654], 'dipped': [2656], 'KodakNTB2': [2658], 'emulsion,': [2659], 'exposed': [2660], '1–6': [2662], 'weeks,': [2663], 'developed': [2665], 'Kodak': [2667], 'D19': [2668], 'developer': [2669], 'following': [2670], 'protocols.': [2673], 'After': [2674, 3260, 3537], 'development,': [2675], 'examined': [2678], 'photographed': [2680], 'under': [2681], 'phase': [2682], 'optic': [2683], 'dark': [2685], 'field': [2686], 'illumination.': [2687], 'Immunohistochemistry—Mouse': [2688], 'tissues': [2691], 'different': [2695], 'developmental': [2696], 'stages': [2697], 'then': [2699, 3527], 'processed': [2700], 'standard': [2704], 'method': [2705], 'embedded': [2727], 'paraffin.': [2729], 'Immunostaining': [2730], '(8Zhou': [2739], 'Goat': [2758], 'polyclonal': [2759, 4043], 'antibody': [2760, 3338, 4044, 4087], 'against': [2761, 4045], 'acids': [2763], '(Santa': [2766], 'Cruz': [2767, 3341], 'Biotechnology,': [2768], 'Santa': [2769, 3340], 'Cruz,': [2770], 'CA;': [2771], 'sc-17230)': [2772], 'dilution': [2777], '1:25': [2779], 'after': [2780, 3306], 'blocking': [2781], 'tissue': [2782], 'horse': [2786], 'serum': [2787], 'phosphate-buffered': [2789], 'saline/0.2%': [2790], 'Triton': [2791, 3503, 3666], 'X-100.': [2792], 'Plasmids—pCMV-TAZ': [2793], 'amplification': [2798, 2884, 2916, 2939], 'coding': [2802, 2887, 2919, 2942], 'cloning': [2806, 2923], 'EcoRI-MluI': [2809], 'pCMV5': [2813], 'vector': [2814, 2932, 2959], '(37Andersson': [2815], 'Davis': [2817], 'D.L.': [2818], 'Dahlback': [2819], 'Jornvall': [2821], 'Russell': [2823], 'D.W.': [2824], '264:': [2829], '8222-8229Abstract': [2830], 'pEGFP-TAZ,': [2837], 'pEGFP-TAZ/S89A,': [2838], 'pEGFP-TAZ/-4': [2840], 'produced': [2842, 3305], 'GST·TAZ': [2877, 3562], 'fusion': [2878, 2905, 3473], 'subcloning': [2891], 'EcoRI-XhoI': [2894], 'pGEX-4T3': [2898], 'vector.': [2899], 'correct': [2901], 'frame': [2902], 'verified': [2907], 'DNA': [2909, 3037, 3249], 'sequencing.': [2910], '3xFLAG-TTF-1': [2911], 'EcoRV-BamHI': [2926], '3xFLAG': [2930, 2957], 'CMV-10': [2931, 2958], '(Sigma).': [2933, 2960, 3681], '3xFLAG-Δ3': [2934], 'Δ3': [2948, 2997], 'subcloned': [2950, 3396], 'NotI-XbaI': [2953], 'plasmids': [2962], 'transient': [2966], 'transfection': [2967, 3307], 'CMV-TTF-1': [2977], 'Scholar),': [2994], 'Δ14,': [2995], 'Reporter': [3026, 3084], 'constructs': [3027, 3211], 'luciferase': [3030, 3271, 4159], '4.8-': [3034], '0.32-kb': [3036], 'fragments': [3038], '5′-flanking': [3041], '(4.8': [3048, 4139], 'mSP-C-luc': [3049, 3213, 3216, 4427], '0.32': [3051, 3215, 4426], 'mSP-C-luc,': [3052], 'respectively)': [3053], 'made': [3055], '(14Kelly': [3057], 'Culture': [3082], 'Assays—MLE-15': [3085], 'cloned': [3088], 'SV40': [3089], 'large': [3090], 'T': [3091], 'antigen': [3092], 'endogenous': [3100], '(39Wikenheiser': [3105], 'K.A.': [3106], 'Vorbroker': [3107], 'D.K.': [3108], 'Rice': [3109], 'Oie': [3115], 'H.K.': [3116], 'Proc.': [3119], 'Natl.': [3120], 'Acad.': [3121], 'Sci.': [3122], 'U.': [3123], '90:': [3127], '11029-11033Crossref': [3128], '(294)': [3131], 'cultured': [3137, 3180], 'HITES': [3139], 'medium': [3140, 3185], '(RPMI': [3141], '1640': [3142], '10': [3144, 3150, 3547, 3569, 3581], 'mm': [3145, 3164, 3460, 3485, 3491, 3494, 3548, 3553, 3556, 3560, 3570, 3573, 3578, 3658, 3663, 3671, 3674], 'HEPES,': [3146], 'insulin,': [3149], 'transferrin,': [3152], '3': [3153, 3622], '×': [3154, 3159, 3203], '10-8m': [3155, 3160], 'selenite,': [3157], 'β-estradiol,': [3161], '200': [3163], 'l-glutamine)': [3165], 'seeded': [3168, 3197], '40–50%': [3170], 'confluence': [3171], '6-well': [3173, 3207], 'plates': [3174], 'transfection.': [3176], "Dulbecco's": [3182], 'modified': [3183], "Eagle's": [3184], '10%': [3187, 3668], 'calf': [3189], 'serum.': [3190], 'For': [3191], 'experiments,': [3193], 'density': [3200], '2': [3202], '105': [3204], 'cells/well': [3205], 'plates.': [3208], '4.8': [3212, 4143, 4424], 'co-transfected': [3218, 4134], 'empty': [3220, 3258], 'vector,': [3221], 'vectors': [3223], 'transactivators': [3225], '(TAZ,': [3226], 'their': [3229, 3721], 'variants;': [3230], 'see': [3231], '"Plasmids"),': [3232], '0.5': [3234, 3484, 3490], 'μg': [3235, 3610], 'pCMV-β-galactosidase': [3237], 'FuGENE': [3239], '6': [3240], '(Roche': [3241], 'Applied': [3242], 'Science).': [3243], 'amount': [3246, 3256], 'transfected': [3248, 4244, 4409], 'adding': [3253], 'corresponding': [3255], 'vectors.': [3259], '48': [3261], 'h': [3262], 'incubation,': [3264], 'lysates': [3265, 3321], 'assayed': [3267, 3279], 'β-galactosidase': [3269, 3296], 'Light': [3276], 'units': [3277, 3292], 'luminometry': [3281], '(Monolight': [3282], '3010,': [3283], 'Analytical': [3284], 'Luminescence': [3285], 'Laboratory,': [3286], 'San': [3287], 'Diego,': [3288], 'CA).': [3289], 'Relative': [3290], 'light': [3291], 'normalized': [3294], 'Levels': [3298], 'measured': [3309], 'immunoblot': [3311], 'lysates.': [3316], 'Total': [3317], '10–20%': [3325], 'SDS-PAGE': [3326, 3694], 'transferred': [3328], 'nitrocellulose': [3330], 'membrane.': [3331], 'Blots': [3332], 'incubated': [3334], 'goat': [3336, 4042], 'anti-GFP': [3337], '(1:100,': [3339], 'Biotechnology)': [3342], 'EGFP-tagged': [3344], 'variants': [3348], 'monoclonal': [3350], 'anti-TTF-1': [3351], 'Ab-1': [3352], '(clone': [3353], '8G7G3/1,': [3354], 'Neo': [3355], 'Markers,': [3356], 'Lab': [3357], 'Vision': [3358], 'Corp.)': [3359], 'variants.': [3364], 'Two-hybrid': [3366], 'System': [3367], 'Assays—The': [3368], 'reporters': [3369], 'pG5Luc': [3370], 'pM/TTF-1': [3372], 'kind': [3374], 'gifts': [3375], 'Cong': [3378], 'Yan,': [3379], 'OH).': [3384], 'full': [3389], 'length': [3390], 'cut': [3392], 'EcoRI': [3394, 3402], 'pVP16': [3398], '(Clontech)': [3399], 'site.': [3403], 'Transfection': [3404], '(38Naltner': [3414], '56-62Abstract': [3427], '(57)': [3435], 'Vitro': [3439], 'Protein': [3440, 3594], 'Interaction—GST·TAZ': [3441], 'BL21': [3446], '(DE)': [3447], 'LysS': [3448], 'bacterial': [3449], 'transformed': [3451], 'pGEX-TAZ.': [3453], 'At': [3454, 3971], 'A600': [3455], '=': [3456, 4094], '0.6,': [3457], 'isopropyl-1-thio-β-d-galactopyranoside': [3458], '(0.1': [3459], 'final)': [3461], 'added': [3463, 3506], 'culture': [3466], 'induce': [3468], 'protein,': [3474], 'resuspended': [3478], 'lysis': [3480], 'buffer': [3481, 3545, 3567, 3655, 3696], '(phosphate-buffered': [3482], 'saline,': [3483], 'EDTA,': [3486, 3557], 'mg/ml': [3488], 'lysozyme,': [3489], 'dithiothreitol,': [3492, 3672], 'phenylmethylsulfonyl': [3495, 3675], 'fluoride,': [3496, 3676], 'protease': [3497, 3678], 'inhibitors': [3498, 3679], 'diluted': [3499], '1:1000)': [3500], 'sonicated.': [3502], 'X-100': [3504], '1%,': [3508], 'extract': [3512, 3627], 'centrifuged': [3514], '40,000': [3516], 'rpm': [3517], '40': [3519], '4': [3522, 3584, 3609, 3642], 'supernatant': [3525], 'subjected': [3528], 'affinity': [3530], 'chromatography': [3531], 'glutathione-Sepharose': [3533], 'beads': [3534, 3539, 3620, 3690], '(Amersham': [3535], 'Biosciences).': [3536], 'binding,': [3538], 'washed': [3541, 3650], 'times': [3543, 3652], 'Tris-HCl,': [3549, 3574, 3659], 'pH': [3550, 3575, 3660], '8.0,': [3551, 3576], '100': [3552, 3662, 4095], 'NaCl,': [3554, 3579, 3664], 'dithiothreitol.': [3561], 'eluted': [3564, 3587, 3686], 'glutathione,': [3571], 'stored': [3590], '-80': [3592], 'concentration': [3595], 'judged': [3597], 'Coomassie': [3599], 'Blue': [3600], 'staining.': [3601], 'assay': [3604], 'incubating': [3608], 'GST': [3612], 'GST·TAZ-purified': [3614], 'bound': [3616, 3683], 'glutathione-agarose': [3619], 'mg': [3623], 'reactions': [3634], 'carried': [3636], 'out': [3637], '90': [3639], 'rotating': [3646], 'wheel.': [3647], 'Beads': [3648], 'several': [3651], '7.5,': [3661], '0.1%': [3665], 'x-100,': [3667], 'glycerol,': [3669], '(1:1000)': [3680], 'resuspending': [3688], '2×': [3693], 'sample': [3695], 'heating': [3698], '3–5': [3703], 'before': [3705], 'loading': [3706], 'gel.': [3709], 'Is': [3711], 'Expressed': [3712], 'Respiratory': [3714], 'Epithelial': [3715], 'Cells': [3716], 'Developing': [3719], 'Lung—Since': [3720], 'structures': [3722], 'indicate': [3723], 'expression,': [3738], 'relevant': [3741], 'test': [3743, 4461], 'whether': [3744, 3755, 4117, 4462], 'two': [3746], 'co-exist': [3748], 'temporal/spatial': [3757], 'consistent': [3768], 'RT-PCR,': [3773], 'hybridization,': [3776], 'immunohistochemical': [3778], 'performed.': [3781], 'RT-PCR': [3782], 'conducted': [3784], '18.0.': [3799], 'all': [3805], 'ages': [3806], 'tested,': [3807], 'level': [3810], 'gradually': [3814], 'increased': [3815, 4163, 4350, 4418], 'advancing': [3817], 'gestation': [3818], '(Fig.': [3819, 3837, 3951, 3993, 4022, 4181, 4198, 4262, 4442], '1A).': [3820], 'relatively': [3827], 'high': [3828], '1B),': [3838], 'known': [3841], '(7Stahlman': [3848], 'assessed': [3919], 'E11.5–18.0.': [3925], 'first': [3930], 'buds': [3935], 'E12.5': [3937, 4057, 4080], '(data': [3938], 'shown),': [3940], 'epithelium': [3945, 3981, 4017, 4055], 'more': [3947], 'E13.5': [3950, 4060], '1C).': [3952], 'diffuse': [3963], 'signal': [3964, 4091], 'mesenchyme.': [3970], 'E18.0,': [3972], 'primarily': [3977, 4014], 'conducting': [3991, 4075], 'airways': [3992, 4076], '1E).': [3994], 'Immunohistochemistry': [3995], 'identify': [3999], 'staining': [4011], '2,': [4023], 'B–D).Fig.': [4024], '2Immunohistochemical': [4025], 'detection': [4026], 'Paraffin': [4033], 'immunostained': [4040], 'mainly': [4050], '(B)': [4058], '(C)': [4061], 'E17.5': [4069], '(D)': [4070], '(Br,': [4077], 'bronchioles).': [4078], 'section': [4082], 'stained': [4083], 'without': [4084], 'showed': [4088], 'no': [4089], 'detectable': [4090], '(A).': [4092], 'Bars': [4093], 'μm.View': [4096], 'Large': [4097], 'Image': [4098], 'Figure': [4099], 'ViewerDownload': [4100], 'Hi-res': [4101], 'image': [4102], 'Download': [4103], '(PPT)': [4104], 'Synergistically': [4108], 'Activate': [4109], 'Promoter—To': [4115], 'influences': [4119], 'promoter,': [4125], 'alone': [4127], 'transiently': [4133], 'plasmid': [4138], 'mSP-C-luc)': [4140], 'consisting': [4141], 'kb': [4144], 'protein-C': [4153], 'gene,': [4154], 'Sftp-c,': [4155], 'gene.': [4161], 'effects': [4175, 4253, 4436, 4464], '3A).': [4182], 'smaller': [4187], 'fragment': [4190], '(0.32': [4191], 'mSP-C),': [4192], 'albeit': [4193], 'lesser': [4196], 'extent': [4197], '3B).': [4199], 'Likewise,': [4200], 'artificial': [4207], 'TTF-1-responsive': [4208], 'consists': [4211], 'five': [4213], 'consecutive': [4214], 'controls': [4220], 'acetyltransferase': [4224], '(CAT)': [4225], '(C5-CAT)': [4226], '2M.': [4230], 'Zannini,': [4231], 'unpublished': [4232], 'results.': [4233], 'supporting': [4234], 'When': [4240], 'amounts': [4247, 4403], 'stimulatory': [4252], '3E).': [4263, 4443], 'Since': [4264], 'represent': [4278], 'co-activation.': [4279], 'Two': [4280], 'mutants': [4282, 4407], 'previously,': [4285], 'substituting': [4286], 'serine': [4288], 'residue': [4289], 'alanine': [4295], '(TAZ': [4296], 'S89A)': [4297], 'deleting': [4299], 'last': [4301], 'four': [4302], 'residues': [4304], '(TAZ-4)': [4305], 'within': [4306], 'motif,': [4309], 'respectively': [4310], 'Previously,': [4343], 'S89A': [4349, 4415], '1.5–2-fold': [4354], 'compared': [4356], 'wild': [4358], 'type,': [4359], 'TAZ-4': [4361], 'ability': [4364], 'co-activate': [4366], 'Increasing': [4402], 'these': [4405], 'active': [4414], 'both': [4423], 'reporters,': [4428], 'inhibitory': [4431], 'mutant,': [4432], 'TAZ-4,': [4433], 'blocked': [4434], 'TTF-1-dependent': [4440], 'TAZ-mediated': [4446], 'co-activation': [4448], 'involves': [4453], 'domain-containing': [4458], 'cell-speci': [4474]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2049378557', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 12}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 13}, {'year': 2013, 'cited_by_count': 16}, {'year': 2012, 'cited_by_count': 14}], 'updated_date': '2024-12-18T09:38:27.785811', 'created_date': '2016-06-24'}
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