Publication Information

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846, 856, 877, 886, 894, 969, 977, 994, 1173, 1179, 1189, 1201, 1219, 1241, 1275, 1356, 1370, 1425, 1489, 1507, 1514, 1571, 1598, 1629, 1681, 1694, 1699, 1775, 1820, 1847, 1881, 1915, 1933, 1943, 1946, 1968, 1987, 2034, 2109], 'up': [96, 931], 'physicians': [99], 'determine': [101], 'most': [103, 1778], 'method': [105, 236, 976, 1072, 1506, 1570, 1619, 1774], 'an': [109, 393, 575, 604, 778, 801, 857, 1271, 1563, 1891], 'individual': [110, 962], 'basis.': [111], 'Microscopically': [112, 191, 2086], 'controlled': [113, 192, 510, 1157, 2055, 2087, 2148], 'surgery': [114, 193, 855, 1158, 1651, 2026, 2056, 2088, 2149], '(MCS)': [115], 'aims': [116], 'insure': [118, 188], 'complete': [119, 205, 242, 1859], 'removal': [120, 179, 207, 243, 280, 1861, 2091], 'malignancy': [123], '(R0': [124, 244], 'resection)': [125], 'histological': [127, 200, 238, 327, 363, 495, 731, 832, 999, 1391, 1471, 2030, 2048, 2069, 2072], 'confirmation': [128], 'while': [129], 'sparing': [130, 2144], 'as': [131, 137, 231, 233, 455, 674, 708, 1006, 1643, 1645, 1727, 1729, 1760], 'much': [132, 1620], 'adjacent': [135], 'tissue': [136, 216, 606, 619, 638, 667, 826, 876, 957, 1115, 1205, 1355, 1379, 1419, 1442, 1536, 1672, 1819, 1913, 2164], 'possible.': [138, 760, 1372], 'The': [139, 416, 527, 541, 590, 618, 991, 1177, 1287, 1399, 1512, 1584, 1771, 1869, 1979, 2032, 2115], 'subclinical': [140], 'extent': [141], 'skin': [143, 313, 1187, 2094], 'cancer': [144, 2095], 'often': [146], 'difficult': [147, 1021, 1656, 1686], 'assess': [149, 715, 1023, 2003], 'prior': [150, 465, 1865], 'therapy': [152], 'macroscopic': [156], 'appearances': [157], 'alone.': [158], 'There': [159], 'thus': [161, 1552, 1858], 'risk': [163], 'choosing': [165], 'margin': [167, 630, 1203, 1432, 2013], 'safety': [169], 'either': [172, 1301], 'too': [173, 176], 'large': [174, 282, 803, 946, 1594, 1609], 'small.': [177], 'Complete': [178], 'tumor': [182, 330, 597, 785, 930, 941, 1130, 1172, 1224, 1254, 1293, 1339, 1498, 1637, 1782, 1860, 1873], 'only': [185, 517, 547, 1934], 'way': [186], 'cure.': [190], 'performed': [195, 250, 353, 490, 859, 895, 1357, 1413], 'conjunction': [197], 'various': [199], 'processing': [201, 736, 893, 968, 1363, 2020], 'ensure': [204, 2007], 'surgical': [206, 229, 1692], 'tumor.': [210, 589, 905, 1211, 1923], 'In': [211, 478, 805, 818, 1119, 1166, 1212, 1235, 1256, 1473, 1924, 2011], 'all': [212, 1150, 1167], 'procedures,': [213], 'excised': [215, 1049, 1206, 1268, 1922], 'marked': [218, 965], 'for': [219, 296, 392, 545, 979, 998, 1149, 1191, 1277, 1387, 1470, 1574, 1652, 1683, 1823, 1838, 1993, 1995, 2089, 2143, 2176], 'precise': [220, 271], 'topographical': [221, 272, 655], 'orientation.': [222], 'These': [223, 670], 'procedures': [224, 370, 1887, 1967], 'differ': [225], 'terms': [227, 528, 1089], 'technique': [230, 421, 485, 542, 1062, 1080, 1200, 1376, 1628, 1693], 'well': [232, 996, 1728], 'sectioning': [239, 502, 1791], 'confirm': [241, 1890, 2129], 'resection).': [245], 'Histological': [246, 892, 967], 'techniques': [247, 1034, 1099, 1170, 1258, 1662, 1853], 'may': [248, 293, 307, 318, 614, 659, 836, 958, 1322, 1443, 1560, 1674, 1784], 'single,': [252], 'dual,': [253], 'multiple': [255], 'interventions.': [256], 'Immediate': [257], 'closure': [258, 303, 1852], 'wound': [261, 317, 342, 816, 1867], 'possible,': [263], 'especially': [264, 984, 1572, 1821], 'it': [266, 1457, 1488, 1524, 1559, 1631, 1846, 1942, 1945], 'interfere': [269], 'orientation': [273, 1347], 'any': [275, 724, 1117, 1669, 1910, 1962, 2008], 'potentially': [276], 'necessary': [277, 725], 're-excisions.': [278], 'For': [279, 654, 945, 1137, 1308, 1593, 1649], 'tumors': [283, 285, 947, 1009, 1684, 1840, 1925, 2135], 'at': [286, 346, 582, 1134, 1280, 1685, 1841, 1939, 2139, 2166], 'problematic': [287, 1871], 'sites,': [288], 'suitable': [290, 544, 978], 'protective': [291], 'bandage': [292], 'used': [295, 459, 516, 661, 1091, 1677, 1837, 2052], 'temporary': [297], 'coverage': [298], 'before': [299], 'final': [300], 'closure.': [301, 1193, 1868], 'Later': [302], 'defect': [306, 1192], 'plastic': [310], 'reconstruction,': [311], 'free': [312], 'grafting,': [314], 'allowed': [320], 'close': [322], 'by': [323, 411, 451, 548, 1302, 1359, 1414, 2037, 2044], 'secondary': [324], 'healing.': [325], 'If': [326, 1941], 'analysis': [328, 496], 'reveals': [329], 'extending': [331, 787], 'margins': [334, 374, 683, 795, 822, 1047, 1111, 1245, 1260, 1288, 1318, 1403, 1480, 2023], 'excision,': [336], 'affected': [338, 1876], 'border': [339], 'zone': [340, 1642], 'base': [343, 927, 1247, 1263, 1290, 1405, 1434], 'identified': [345], 'excision': [348, 470, 488, 602, 794, 1218], 'site': [349], 're-excision': [351, 756, 1240], 'aim': [356], 'R0': [358, 394, 1564, 1705, 1892, 2132], 'resection.': [359, 395], 'With': [360], 'regard': [361], 'analysis,': [364], 'distinction': [366], 'between': [369, 556, 1496, 1671, 1817, 1912, 2162], 'show': [372, 1113], 'no': [376, 386, 1052, 1815, 2160], 'gaps': [377, 387, 1547, 1604, 1670, 1816, 1911, 2161], 'those': [379], 'have': [381, 388, 399, 1733, 1738, 1927], 'gaps.': [383, 1118], 'Methods': [384, 1154], 'highest': [390], 'sensitivity': [391, 1597, 1899], 'Yet': [396], 'whether': [397, 1129], 'they': [398, 687, 835, 1093], 'significant': [401, 774], 'influence': [402], 'tumor-free': [404, 1641], 'survival': [405], 'has': [406, 563, 1146, 1421, 1566], 'yet': [408], 'been': [409, 1147, 1422, 1567], 'confirmed': [410, 981], 'prospective,': [412], 'randomized': [413], 'studies.': [415], 'usefulness': [417], 'chosen': [420], 'depends': [422, 733, 2121], 'expertise': [425, 1972], 'experience': [427, 2124], 'surgeon': [430, 1304, 1976, 1984, 2000, 2016, 2101], 'histologist,': [432], 'who': [433, 705, 2108], 'occasionally': [435], 'one': [436, 1658], 'same': [439], 'person.': [440], 'This': [441, 512, 975, 1229, 1459, 1503, 1569, 1794], 'procedure': [442, 473, 508, 513, 558, 768, 1068, 1239, 1460, 1932, 2120], 'was': [443, 475, 489, 497], 'introduced': [444], '1941': [446], 'United': [449, 525], 'States': [450], 'F.': [452], 'Mohs,': [453], 'initially': [454], 'chemosurgery.': [456], 'Originally': [457], 'Mohs': [458, 505, 1486], 'fixative': [461], 'zinc': [462], 'chloride': [463], 'paste': [464], 'performing': [467], 'actual': [469], 'very': [476, 1504, 1612, 1947], 'painful.': [477], '1974': [479], 'Tromovitch': [480], 'published': [481], 'cryostat': [484, 503, 649, 898, 954, 1026, 1792], 'which': [487, 845, 899, 1188, 1689], 'under': [491, 579, 840, 1510], 'local': [492, 570, 580, 1704, 2131], 'anesthesia': [493, 581], 'done': [498], 'rapid': [501, 1378, 1790], 'technique.': [504, 1528], 'called': [506], '“microscopically': [509], 'surgery.”': [511], 'currently': [515], 'certain': [519, 1991], 'specialized': [520], 'clinics,': [521], 'mainly': [522], 'States.': [526], '“Mohs’': [529, 533], 'micrographic': [530], 'surgery”': [531, 534], 'also': [536, 689, 698, 811, 837, 971, 1127, 1371, 1411, 1508, 1675, 1758, 2002, 2110], 'found': [537], 'literature.': [540], 'use': [546, 1585], 'specially': [549, 2099], 'trained': [550, 2046, 2100], 'dermatologic': [551], 'surgeons.': [552], 'One': [553, 851], 'key': [554], 'difference': [555], 'this': [557, 767, 798, 1618, 1627], 'others': [560], '(see': [561], '2.2)': [562], 'do': [565, 949], 'incision.': [568], 'Following': [569], 'curettage': [571], 'exophytic': [573], 'components,': [574], 'incision': [576, 746, 780, 783, 809, 821, 858, 1178, 1272, 1479, 1501, 1513, 1647, 2168], '45': [584], 'degree': [585, 1897], 'angle': [586], 'around': [587, 681, 1207], 'scalpel': [591, 658], 'angled': [593, 629, 779], 'away': [594], 'from': [595, 651, 925, 1243, 1266, 1333, 1534], 'so': [598, 626, 2074], 'circular': [601], 'removes': [603], 'upside-down': [605], 'cone.': [607], 'Depending': [608], 'its': [610], 'size,': [611], 'specimen': [613, 679, 1463], 'then': [615, 621, 1532, 1781, 1956], 'divided.': [617], 'pressed': [622], 'onto': [623], 'slide': [625], 'level': [632], 'base.': [635], 'Next': [636, 2267], 'embedded': [640], 'resulting': [643, 916], 'block': [644], 'cut': [646, 890, 1324], 'horizontally': [650], 'margin.': [653, 1502], 'orientation,': [656], 'place': [663], 'cuts': [664, 1519], 'situ.': [669], 'tiny': [671], 'incisions': [672, 2005], 'remain': [673], 'slight': [675], 'indentations': [676], 'wound;': [686], 'visible': [690, 1133], 'microscopic': [693], 'specimen.': [694], 'Dye': [695, 1344], 'marking': [696, 1345], 'common.': [699], 'Using': [700, 1373], 'automatic': [701], 'staining,': [702, 1297], 'surgeon,': [704], 'basically': [706], 'functions': [707], 'his': [709], 'her': [711], 'own': [712], 'dermatohistopathologist,': [713], 'can': [714, 747, 810, 942, 1340, 1393, 1410, 1589, 1889, 1955, 2001, 2017, 2079], 'sections': [717, 732, 908, 924, 1392, 1530, 1540, 1588, 1614, 1813, 2073], 'within': [718], 'hour': [720], 'immediately': [722, 2024], 'perform': [723, 2018], 're-excision.': [726], 'Correct': [727], 'interpretation': [728], 'greatly': [734], 'requires': [738, 2096], 'highly': [739, 1885], 'qualified': [740], 'laboratory': [741, 1306, 1417, 1469], 'personnel.': [742, 1307], 'Inadequate': [743], 'embedding': [744], 'produce': [748], 'incomplete': [749], 'incorrectly': [751], 'oriented': [752], 'margins.': [753, 817, 891, 1136, 1234, 2169], 'Reproducibility': [754], 'usually': [758, 1279], 'Given': [761], 'complexity': [763], 'time': [765, 973, 1427, 1622], 'involved,': [766], 'prone': [770], 'error.': [772], 'A': [773, 1329], 'drawback': [775], 'using': [777, 1225, 1516, 2060], 'components': [786, 1131, 1950], 'lower': [790, 1599], 'dermis.': [791], 'Increasing': [792], 'avoid': [797], 'results': [799], 'unnecessarily': [802], 'defect.': [804], 'addition,': [806], 'oblique': [808], 'complicate': [812], 'adaptation': [813], 'principle,': [819], 'three-dimensional': [820, 843, 936, 1110], 'removed': [825, 879, 1174], 'fully': [828], 'shown': [829], 'two-dimensional': [831], 'sections.': [833, 920, 1027, 1350], 'Thus': [834], 'subsumed': [839, 1509], 'term': [842, 1143], 'histology,': [844], 'discussed': [847], 'following.': [850], 'variation': [852], 'Mohs’': [854, 873, 1996], 'parallel': [860, 919], "skin's": [863], 'surface': [864, 1184], '(the': [865], '“Münchner”': [866], 'method)': [867], '(Burg': [868], 'Konz': [870], '1975).': [871], 'Unlike': [872], 'technique,': [874, 1487], 'cone': [882], 'shape,': [883], 'but': [884, 1424], 'rather': [885], 'cylinder-shaped': [887], 'perpendicularly': [889, 1181], 'enables': [900, 1632], 'assessment': [901, 1634], 'whole': [904], 'Micrometer-wide': [906], 'sequential': [907, 923, 1517], 'prepared': [910], '(maximum': [911], '10': [912], '=': [913], '0.001': [914], 'mm)': [915], 'numerous': [918], 'By': [921], 'evaluating': [922], 'epidermis,': [934], 'growth': [937, 1701, 2138], 'pattern': [938], 'assessed.': [944, 1483], 'fit': [951], 'slide,': [955], 'divided': [960], 'blocks': [963], 'topographically.': [966], 'necessarily': [970], 'more': [972, 1426, 1621, 1850, 1870, 1879], 'consuming.': [974, 1428, 1623], 'histologically': [980, 1958], 'epithelial': [982], 'tumors,': [983, 1657, 1825], 'basal': [985, 1713, 1720, 1907], 'cell': [986, 1018, 1714, 1721, 1755, 1802], 'carcinomas': [987, 1731], 'recurrent': [989, 1719, 1824], 'disease.': [990, 1770, 1807], '“Münchner': [992], 'method”': [993], 'less': [995, 1578], 'suited': [997, 1573], 'evaluation': [1000, 2033], 'superficial': [1002], 'precancerous': [1003], 'lesions': [1004], 'such': [1005], 'lentiginous': [1007, 1751], 'melanocytic': [1008], 'Paget': [1011, 1766, 1806], 'Bowen': [1013, 1769], 'disease,': [1014, 1767], 'given': [1015, 1600, 1780], 'pathological': [1017], 'structures': [1019], 'Various,': [1028], 'similar': [1029], 'alternatives': [1030], 'above-mentioned': [1033, 1366], 'described': [1036], 'literature:': [1039], 'La': [1040, 1237], 'Galette': [1041, 1238], '(Drepper': [1042], '1963)': [1043], 'histology': [1044, 1145, 1169, 1299, 2067], 'tissue,': [1050, 2146], 'gaps,': [1053], '“Tübinger': [1055], 'tort”': [1056], '(Breuninger': [1057, 1063], '1982),': [1058], 'Flunder': [1059], 'muffin': [1061], '1994,': [1064], 'Möhrle': [1065], '2006),': [1066], 'square': [1067, 1214, 1217], '(Johnson': [1069], '1997),': [1070], 'quadrant': [1071, 1408], '(Smeets': [1073], '2005),': [1074], 'Wallgraben': [1077, 1199], 'perimeter': [1079, 1197], '(Blum': [1081], '2004,': [1082], 'Mahoney': [1083], '2005).': [1084], 'Although': [1085], 'some': [1086], 'these': [1088, 1107, 1152], 'synonymously,': [1092], 'fact': [1095], 'refer': [1096], 'different': [1098], 'distinct': [1101], 'advantages': [1102, 1367], 'disadvantages.': [1104], 'All': [1105, 2050], 'involve': [1109, 1668], 'without': [1116, 1296, 1909], 'addition': [1120], 'central': [1123, 1284, 1335], 'section,': [1124], 'histo-pathologist': [1126], 'evaluates': [1128], 'purpose': [1139], 'simplification,': [1141], '3-D': [1144, 1168], 'proposed': [1148], 'methods.': [1153, 2114], 'microscopically': [1156, 2054, 2147], '(MCS).': [1159], '(Illustration:': [1160], 'Professor': [1161], 'Dr.': [1162, 2179, 2185, 2191, 2196, 2201, 2206, 2212, 2218, 2224, 2230, 2235, 2241, 2247, 2254], 'Helmut': [1163, 2249], 'Breuninger,': [1164, 2250], 'Tübingen).': [1165], 'en': [1175], 'bloc.': [1176], 'preferable': [1190], 'Only': [1194], 'situ': [1210, 1249], 'procedure,': [1215], 'remove': [1222], 'double-bladed': [1227], 'scalpel.': [1228], 'facilitates': [1230, 1346], 'separation': [1231], 'preliminarily': [1252], 'narrow': [1253], 'excision.': [1255], 'other': [1257], 'separated': [1265, 1431], 'tissue.': [1269], 'Intraoperatively': [1270], 'thread': [1274], 'placed': [1276, 1436], 'marking,': [1278], '12:00': [1281], 'o’clock': [1282], '(most': [1283], 'cranial': [1285], 'point).': [1286], 'embedded,': [1295], 'cassettes,': [1300], 'small': [1309, 1575], 'excisions': [1310, 1576], '(up': [1311], '2': [1313, 1388], 'cm': [1314], 'diameter)': [1316], 'underside': [1321], 'leveled': [1326], '(muffin': [1327], 'technique).': [1328], 'representative': [1330], 'section': [1331, 1773], 'taken': [1332, 2078, 2165], 'portion': [1336], 'aid': [1341, 2028], 'classification.': [1343], 'Usually': [1351], 'formalin': [1352, 1385], 'fixation': [1353, 1380], 'followed': [1358], 'paraffin': [1360, 1375, 1772, 1812], 'embedding.': [1361], 'Cryostat': [1362], '(with': [1364], 'disadvantages)': [1369], '60°': [1383], 'C': [1384, 1448], 'solution': [1386], 'hours,': [1389], 'ready': [1395], 'next': [1397], 'day.': [1398], 'preparation': [1400], '(“Tübinger': [1406], 'tort”,': [1407], 'technique)': [1409], 'histopathological': [1416], 'fixed,': [1423], 'First,': [1429], 'paraffin.': [1438], 'Next,': [1439], 'wax-like': [1441], 'heated': [1445], '65°': [1447], 'outer': [1451], 'side': [1452], 'slightly': [1453], 'bent': [1454], 'make': [1456], 'level.': [1458], 'allows': [1461], 'sent': [1466], 'analysis.': [1472, 2049], 'peripheral': [1475, 1661, 2012], 'method,': [1476, 2155], 'far': [1477, 1644], 'fewer': [1478], 'Similar': [1484], 'possible': [1491], 'evaluate': [1493], 'distance': [1495], 'common': [1505], 'MCS.': [1511], 'vertical': [1518], 'scalpel,': [1522], 'lending': [1523], 'name': [1526], 'bread-loaf': [1527], 'Representative': [1529], 'slices.': [1537], 'When': [1538], '1': [1542, 2272], 'mm': [1543, 1581], 'larger,': [1545], 'presumed,': [1550], 'depending': [1553], 'number': [1556, 1610], 'slices,': [1558, 1914], 'appear': [1561], 'resection': [1565, 1706, 1893, 2133], 'achieved.': [1568], 'measuring': [1577], 'than': [1579, 1788], '20': [1580], 'diameter.': [1583], 'thin': [1587, 1613], 'allow': [1590], 'higher': [1591], 'sensitivity.': [1592], 'excisions,': [1595], 'however,': [1596], 'increase': [1605], '–': [1606], 'unless': [1607], 'made,': [1616], 'An': [1624], 'advantage': [1625], 'thorough': [1633], 'architecture': [1638], 'border.': [1648], 'follow-up': [1650], 'R1': [1653], 'resections': [1654], '(3-D': [1663], 'histology)': [1664], 'slices': [1673], '(Table': [1678], '1).': [1679], 'MCS': [1680, 1808, 1834, 1966, 2113], 'indicated': [1682], 'sites': [1687, 1843, 2141], 'tissue-sparing': [1691], 'needed': [1695, 1856], 'when': [1697, 1845, 2157], 'there': [1698, 2158], 'aggressive': [1700], 'ensured.': [1709], 'Common': [1710], 'indications': [1711, 1759], 'include': [1712], 'carcinoma': [1715, 1756], '(especially': [1716], 'infiltrative': [1717, 2137], 'types),': [1718], 'carcinomas,': [1722], 'neural': [1724], 'infiltrating': [1725], 'variants,': [1726], 'spinocellular': [1730, 1799], 'infiltrated': [1734, 1928], 'subcutis': [1736], 'moderate': [1739], 'poor': [1741], 'differentiation.': [1742], 'Dermatofibrosarcoma': [1743], 'protu-berans,': [1744], 'lentigo': [1745, 1747, 1828], 'maligna,': [1746], 'maligna': [1748, 1829], 'melanoma,': [1749, 1752, 1830], 'acral': [1750], 'Merkel': [1754, 1801], 'erythroplasia': [1762], 'Queyrat,': [1764], 'extramammary': [1765, 1805], 'preferred': [1776], 'cases,': [1779, 2043], 'extensions': [1783], 'better': [1786], 'evaluated': [1787], 'procedures.': [1793], 'applies': [1795], 'particular': [1797], 'carcinoma,': [1800, 1803], '3D-histology': [1810], 'important': [1822, 1880], 'dermatofibrosarcoma': [1826], 'protuberans,': [1827], 'acrolentiginous': [1832], 'melanoma.': [1833], 'should': [1835], 'malignant': [1839, 2093], 'problem': [1842, 2140], 'expected': [1848], 'complex': [1851], 'will': [1854], 'ensured': [1864], 'site,': [1877], 'sensitive': [1886], 'high': [1896], '(3D': [1900], 'histology).': [1901], 'Visualization': [1902], 'lateral': [1905], 'margins,': [1908], 'independent': [1916], 'diameter': [1919], 'bone,': [1930], 'limited': [1936], 'use,': [1937], 'all.': [1940], 'used,': [1944], 'complicated.': [1948], 'Osseous': [1949], 'decalcified': [1953], 'examined.': [1959], 'Selection': [1960], 'above-named': [1965], 'cooperating': [1975], 'histologist.': [1978], '“personal': [1980], 'union”': [1981], 'histologist': [1986], 'even': [1988], 'relevant': [1989], 'countries': [1992], 'invoicing': [1994], 'surgery.': [1997], 'Ideally,': [1998], 'clinical-histopathological': [2009], 'correlation.': [2010], 'techniques,': [2014], 'after': [2025], 'laboratory.': [2031], 'generally': [2035], 'histopatho-logist,': [2039], 'special': [2042], 'surgeons': [2045], 'documented': [2059], 'drawings': [2061], '(e.g.,': [2062], "surgeon's": [2063], 'protocol,': [2064], 'requirements': [2065], 'analysis)': [2070], 'steps': [2077], 'readily': [2081], 'reconstructed': [2082], 'need': [2084], 'be.': [2085], 'qualified,': [2098], 'working': [2102], 'closely': [2103], 'together': [2104], 'histopathologist': [2107], 'familiar': [2111], 'selection': [2116], 'users.': [2127], 'To': [2128], 'represents': [2150], 'safe': [2152], 'proven': [2154], 'particularly': [2156], 'Expert': [2170], 'group': [2171], 'German': [2174], 'Society': [2175], 'Dermatosurgery': [2177], '(DGDC)': [2178], 'med.': [2180, 2186, 2192, 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